Detailed information for compound 1027683

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1462.57 | Formula: C65H95N19O20
  • H donors: 21 H acceptors: 21 LogP: -6.49 Rotable bonds: 59
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1[nH]cnc1)CCCNC(=N)N)Cc1ccccc1)CCC(=O)O)C)CC(=O)O)Cc1ccccc1)CC(=O)N)C(C)C)CCC(=O)O)CO)N)C
  • InChi: 1S/C65H95N19O20/c1-6-33(4)51(67)63(103)83-46(30-85)62(102)77-40(20-22-49(89)90)57(97)84-52(32(2)3)64(104)82-44(27-47(66)86)61(101)80-43(25-36-16-11-8-12-17-36)60(100)81-45(28-50(91)92)58(98)74-34(5)54(94)75-39(19-21-48(87)88)56(96)79-42(24-35-14-9-7-10-15-35)59(99)76-38(18-13-23-72-65(69)70)55(95)78-41(53(68)93)26-37-29-71-31-73-37/h7-12,14-17,29,31-34,38-46,51-52,85H,6,13,18-28,30,67H2,1-5H3,(H2,66,86)(H2,68,93)(H,71,73)(H,74,98)(H,75,94)(H,76,99)(H,77,102)(H,78,95)(H,79,96)(H,80,101)(H,81,100)(H,82,104)(H,83,103)(H,84,97)(H,87,88)(H,89,90)(H,91,92)(H4,69,70,72)/t33-,34-,38-,39-,40-,41-,42-,43-,44-,45-,46-,51-,52-/m0/s1
  • InChiKey: POLCDODVJRUTDT-WSMVMQGPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0101 0.0094 0.0322
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0068 0.005 0.0172
Schistosoma mansoni glutamate synthase 0.0034 0.0005 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0073 0.0253
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0327 0.0392 0.1295
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0791 0.1005 0.3542
Leishmania major regulatory subunit of protein kinase a-like protein 0.0055 0.0033 0.0267
Loa Loa (eye worm) G-protein coupled receptor 0.0101 0.0094 0.0387
Brugia malayi F/Y-rich N-terminus family protein 0.0044 0.0018 0.0055
Trypanosoma brucei hypothetical protein, conserved 0.021 0.0237 0.1817
Brugia malayi hypothetical protein 0.0276 0.0325 0.114
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.015 0.0158 0.0554
Brugia malayi hypothetical protein 0.0082 0.0069 0.0233
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.156 0.2021 0.2021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.008 0.0065 0.0065
Brugia malayi Niemann-Pick C1 protein precursor 0.0208 0.0235 0.0821
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0018 0.019
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0073 0.0253
Loa Loa (eye worm) neuropeptide F receptor 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.1842 0.2394 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.0087 0.0357
Echinococcus multilocularis survival motor neuron protein 1 0.1054 0.1352 0.1352
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0003 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0124 0.0408
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis smad 0.0065 0.0046 0.0046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0004 0.0004
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0748 0.0949 0.2702
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0071 0.0241
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0085 0.0073 0.0551
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0094 0.0085 0.0295
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Entamoeba histolytica prolyl oligopeptidase family protein 0.0085 0.0073 0.0241
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0055 0.0033 0.0131
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0055 0.0033 0.0105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0418 0.0512 0.1692
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0056 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.132 0.1704 0.564
Leishmania major hypothetical protein, conserved 0.015 0.0158 0.1318
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0101 0.0094 0.0094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Echinococcus multilocularis nuclear receptor nhr 48 0.0373 0.0453 0.0453
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0003 0.0014
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.008 0.0065 0.0542
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0057 0.0036 0.0115
Echinococcus multilocularis dnaJ subfamily B 0.133 0.1718 0.1718
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.015 0.0158 0.052
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.012 0.0118 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.025 0.029 0.0826
Loa Loa (eye worm) phosphatidylinositol 3 0.1818 0.2362 0.9866
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0042 0.0015 0.0038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0059
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0037 0.0009 0.0059
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.0124 0.043
Leishmania major hypothetical protein, conserved 0.0055 0.0033 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0158 0.0548
Brugia malayi Importin beta-1 subunit 0.0124 0.0123 0.0426
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0329 0.0394 0.1383
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Leishmania major oligopeptidase b 0.0085 0.0073 0.0602
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0082 0.0069 0.0797
Brugia malayi conserved hypotetical protein 0.0373 0.0453 0.1591
Echinococcus multilocularis snurportin 1 0.132 0.1704 0.1704
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0101 0.0094 0.0387
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0048 0.0023 0.0023
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0005 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0101 0.0094 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0034 0.0111
Leishmania major diacylglycerol acyltransferase, putative 0.009 0.0079 0.0653
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2173 0.2832 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0007 0.0029
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0055 0.0033 0.0105
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.008 0.0065 0.0332
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0025
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.0062 0.0209
Echinococcus multilocularis sodium and chloride dependent glycine 0.0327 0.0392 0.0392
Brugia malayi Tachykinin-like peptides receptor 99D 0.0101 0.0094 0.0322
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0007 0.0053
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.1376
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0659 0.0831 0.2748
Loa Loa (eye worm) phosphatidylinositol 3 0.015 0.0158 0.0655
Toxoplasma gondii non-specific serine/threonine protein kinase 0.015 0.0158 0.1887
Echinococcus multilocularis protein patched 0.0089 0.0078 0.0078
Brugia malayi hypothetical protein 0.0188 0.0208 0.0727
Echinococcus multilocularis G-protein coupled receptor, putative 0.0101 0.0094 0.0094
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0194 0.0217 0.0217
Schistosoma mansoni hypothetical protein 0.0048 0.0023 0.0074
Plasmodium falciparum peptidase, putative 0.0085 0.0073 0.0844
Onchocerca volvulus 0.0048 0.0023 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0073 0.0247
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0101 0.0094 0.0094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Schistosoma mansoni rab6-interacting 0.0044 0.0018 0.0058
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0005 0.0028
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0034 0.0005 0.0013
Entamoeba histolytica hypothetical protein 0.01 0.0092 0.0311
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0055 0.0033 0.0105
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0018 0.0052
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0659 0.0831 0.2922
Schistosoma mansoni hypothetical protein 0.0101 0.0094 0.0307
Onchocerca volvulus 0.0055 0.0033 0.0125
Echinococcus multilocularis beta LACTamase domain containing family member 0.0229 0.0262 0.0262
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0068 0.005 0.0202
Trichomonas vaginalis DNA polymerase eta, putative 0.0107 0.0101 0.0348
Echinococcus multilocularis g-protein coupled receptor 0.0101 0.0094 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0127 0.0128 0.0977
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0013 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0023 0.0072
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0096 0.0087 0.0357
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Loa Loa (eye worm) phosphatidylinositol 3 0.015 0.0158 0.0655
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0373 0.0453 0.1591
Leishmania major DNA polymerase kappa, putative 0.0084 0.0072 0.0593
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0865 0.1103 0.3892
Onchocerca volvulus 0.0406 0.0496 0.2062
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1014 0.1301 0.4588
Onchocerca volvulus 0.0101 0.0094 0.0381
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.2173 0.2832 0.8067
Echinococcus granulosus RUN 0.0044 0.0018 0.0052
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.004 0.0013 0.0037
Trypanosoma cruzi NADH dehydrogenase, putative 0.0034 0.0005 0.0013
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.008 0.0065 0.0757
Leishmania major glycerol uptake protein, putative 0.0042 0.0015 0.0122
Echinococcus multilocularis importin subunit beta 1 0.0124 0.0123 0.0123
Echinococcus multilocularis protoporphyrinogen oxidase 0.0082 0.0069 0.0069
Brugia malayi nuclear receptor NHR-88 0.0791 0.1005 0.3542
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0055 0.0033 0.0033
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0023 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0791 0.1005 0.4194
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0101 0.0094 0.0307
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0004 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0791 0.1005 0.2862
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0055 0.0033 0.0105
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.2173 0.2832 0.2832
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.1067
Loa Loa (eye worm) hypothetical protein 0.0524 0.0652 0.2722
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.1272 0.1641 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Brugia malayi Hemopexin family protein 0.1048 0.1345 0.4743
Loa Loa (eye worm) TYRA-2 protein 0.0101 0.0094 0.0387
Schistosoma mansoni hypothetical protein 0.0086 0.0074 0.0241
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0023 0.0072
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0034 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.011 0.0105 0.0436
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0004 0.0011
Echinococcus granulosus allatostatin A receptor 0.0101 0.0094 0.0267
Trypanosoma brucei unspecified product 0.0099 0.0091 0.0696
Loa Loa (eye worm) serotonin transporter b 0.1842 0.2394 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.0554
Loa Loa (eye worm) isocitrate dehydrogenase 0.008 0.0065 0.0268
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.1091
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.0005 0.0006
Brugia malayi Melatonin receptor type 1A 0.0101 0.0094 0.0322
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.025 0.029 0.348
Echinococcus granulosus neuropeptide receptor A26 0.0607 0.0763 0.2172
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0436 0.0536 0.3551
Loa Loa (eye worm) hypothetical protein 0.0082 0.0069 0.0282
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus granulosus TGF beta signal transducer SmadC 0.0065 0.0046 0.0131
Schistosoma mansoni survival motor neuron protein 0.0215 0.0244 0.0805
Entamoeba histolytica hypothetical protein 0.015 0.0158 0.0542
Echinococcus multilocularis thioredoxin glutathione reductase 0.0298 0.0354 0.0354
Schistosoma mansoni neuropeptide F-like receptor 0.0101 0.0094 0.0307
Brugia malayi nuclear receptor NHR-88 0.0373 0.0453 0.1591
Echinococcus granulosus sex peptide receptor 0.0101 0.0094 0.0267
Schistosoma mansoni neuropeptide F-like receptor 0.0101 0.0094 0.0307
Loa Loa (eye worm) hypothetical protein 0.0269 0.0315 0.1311
Schistosoma mansoni opsin-like receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0013 0.0037
Echinococcus granulosus sterol O acyltransferase 1 0.0042 0.0015 0.0044
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0373 0.0453 0.0453
Schistosoma mansoni sodium/chloride dependent transporter 0.0327 0.0392 0.1295
Echinococcus multilocularis serotonin receptor 0.0101 0.0094 0.0094
Echinococcus granulosus o acyltransferase membrane bound domain 0.0042 0.0015 0.0044
Schistosoma mansoni adenoreceptor 0.0101 0.0094 0.0307
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0072 0.0244
Echinococcus multilocularis serine protein kinase ATM 0.015 0.0158 0.0158
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0327 0.0392 0.1376
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0019 0.0056
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0183 0.0201 0.0695
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0034 0.0005 0.0013
Plasmodium falciparum amino acid transporter, putative 0.0327 0.0392 0.4703
Schistosoma mansoni hypothetical protein 0.0048 0.0023 0.0074
Leishmania major phosphatidylinositol kinase related protein, putative 0.015 0.0158 0.1318
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0106 0.0367
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Brugia malayi Glycosylation related protein 12, isoform 0.0036 0.0007 0.0016
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.015 0.0158 0.1318
Loa Loa (eye worm) hypothetical protein 0.0109 0.0104 0.0432
Echinococcus granulosus sodium and chloride dependent glycine 0.0327 0.0392 0.1117
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0023 0.0136
Toxoplasma gondii hypothetical protein 0.0043 0.0017 0.0184
Echinococcus multilocularis neuropeptide receptor 0.0101 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0085 0.0073 0.0298
Chlamydia trachomatis protoporphyrinogen oxidase 0.0082 0.0069 0.1694
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0004 0.0004
Echinococcus granulosus G protein coupled receptor 139 0.0101 0.0094 0.0267
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Leishmania major glycerol uptake protein, putative 0.0042 0.0015 0.0122
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0055 0.0033 0.0183
Echinococcus granulosus lamin dm0 0.0112 0.0108 0.0308
Onchocerca volvulus 0.0101 0.0094 0.0381
Loa Loa (eye worm) hypothetical protein 0.0082 0.0069 0.0282
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0013 0.0037
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.1601
Loa Loa (eye worm) hypothetical protein 0.0418 0.0512 0.2134
Schistosoma mansoni growth hormone secretagogue receptor 0.0101 0.0094 0.0307
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0094 0.0085 0.0644
Plasmodium vivax hypothetical protein, conserved 0.0229 0.0262 0.3133
Mycobacterium tuberculosis Probable lipase LipD 0.0229 0.0262 0.1374
Schistosoma mansoni hypothetical protein 0.0101 0.0094 0.0307
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0068 0.005 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus granulosus o acyltransferase membrane bound domain 0.0042 0.0015 0.0044
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0096 0.0087 0.0357
Toxoplasma gondii ABC1 family protein 0.0229 0.0262 0.3145
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0025
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0034 0.0005 0.0012
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Leishmania major DNA polymerase eta, putative 0.0052 0.0029 0.0238
Loa Loa (eye worm) neuropeptide F receptor 0.0101 0.0094 0.0387
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0034 0.0005 0.0013
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0229 0.0262 0.1374
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.015 0.0158 0.0158
Loa Loa (eye worm) doublecortin family protein 0.0044 0.0018 0.0072
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0085 0.0073 0.0859
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0052 0.0029 0.0337
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0127 0.0128 0.3216
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0034 0.0005 0.0013
Brugia malayi Inositol-1 0.0038 0.0011 0.0028
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0101 0.0094 0.0307
Leishmania major pyruvate kinase 0.0032 0.0003 0.0015
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0327 0.0392 0.1295
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0085 0.0073 0.0465
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0025
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0055 0.0033 0.0105
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0471 0.0582 0.4879
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0068 0.005 0.0567
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0055 0.0033 0.0378
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Loa Loa (eye worm) G-protein coupled receptor 0.0101 0.0094 0.0387
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0326 0.0391 0.1628
Brugia malayi Steroid receptor seven-up type 2 0.0791 0.1005 0.3542
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0084 0.0071 0.0292
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Onchocerca volvulus 0.0048 0.0023 0.0085
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0085 0.0073 0.0237
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.1376
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0096 0.0087 0.0559
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.1874
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0229 0.0262 0.0865
Brugia malayi Nuclear hormone receptor-like 1 0.0791 0.1005 0.3542
Brugia malayi nuclear receptor NHR-67 0.0373 0.0453 0.1591
Toxoplasma gondii histone lysine-specific demethylase 0.0082 0.0069 0.0812
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0023 0.0186
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0211 0.0239 0.0789
Schistosoma mansoni inositol monophosphatase 0.0038 0.0011 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0791 0.1005 0.3542
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0084 0.0071 0.0071
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1168 0.1504 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0042 0.0015 0.0048
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0543 0.0677 0.3574
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0124 0.0408
Giardia lamblia Kinase, PLK 0.0097 0.0088 0.0522
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0055 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis RUN 0.0044 0.0018 0.0018
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0101 0.0094 0.0307
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0034 0.0005 0.0016
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0056 0.016
Onchocerca volvulus 0.0101 0.0094 0.0381
Trypanosoma cruzi oligopeptidase b 0.0085 0.0073 0.0253
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0055 0.0033 0.0106
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0034 0.0005 0.001
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.015 0.0158 0.1207
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0065 0.0768
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0791 0.1005 0.3325
Loa Loa (eye worm) phosphatidylinositol 3 0.015 0.0158 0.0655
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0791 0.1005 0.3542
Trypanosoma cruzi glycerol uptake protein, putative 0.0042 0.0015 0.0051
Mycobacterium tuberculosis Conserved protein 0.0229 0.0262 0.1374
Brugia malayi Dopamine receptor protein 2 0.0101 0.0094 0.0322
Echinococcus multilocularis sex peptide receptor 0.0101 0.0094 0.0094
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.015 0.0158 0.0554
Mycobacterium tuberculosis Possible oxidoreductase 0.0082 0.0069 0.0349
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.0041 0.0015 0.0056
Echinococcus multilocularis chromobox protein 1 0.0074 0.0057 0.0057
Schistosoma mansoni cpg binding protein 0.0103 0.0095 0.0313
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0042 0.0015 0.0048
Onchocerca volvulus 0.0055 0.0033 0.0125
Giardia lamblia Thioredoxin reductase 0.0034 0.0005 0.0011
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0101 0.0094 0.0322
Onchocerca volvulus Prolyl endopeptidase homolog 0.0085 0.0073 0.0292
Echinococcus granulosus p2X purinoceptor 4 0.0352 0.0426 0.1212
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Loa Loa (eye worm) hypothetical protein 0.0208 0.0235 0.0977
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0183 0.0201 0.0695
Plasmodium falciparum ataxin-2 like protein, putative 0.0125 0.0125 0.1483
Onchocerca volvulus 0.0093 0.0083 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0418 0.0512 0.2134
Entamoeba histolytica hypothetical protein 0.0188 0.0208 0.0721
Schistosoma mansoni biogenic amine receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.015 0.0158 0.052
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0127 0.0128 0.0128
Toxoplasma gondii hypothetical protein 0.0042 0.0015 0.017
Schistosoma mansoni sodium-dependent amino acid transporter 0.0327 0.0392 0.1295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Schistosoma mansoni hypothetical protein 0.0086 0.0074 0.0241
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0069 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.004 0.03
Entamoeba histolytica Ran family GTPase 0.0068 0.005 0.0159
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.015 0.0158 0.0554
Loa Loa (eye worm) hypothetical protein 0.0082 0.0069 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Toxoplasma gondii LsmAD domain-containing protein 0.0125 0.0125 0.1497
Trypanosoma cruzi cAMP response protein 1, putative 0.0055 0.0033 0.0112
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Schistosoma mansoni amine oxidase 0.0082 0.0069 0.0224
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0394 0.0481 0.1689
Schistosoma mansoni hypothetical protein 0.009 0.0079 0.0258
Toxoplasma gondii serine carboxypeptidase s28 protein 0.004 0.0013 0.0142
Loa Loa (eye worm) hypothetical protein 0.0052 0.0029 0.0115
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0003 0.0006
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0327 0.0392 0.1117
Schistosoma mansoni nuclear receptor 0.0373 0.0453 0.1497
Schistosoma mansoni hypothetical protein 0.0215 0.0244 0.0805
Loa Loa (eye worm) hypothetical protein 0.0082 0.0069 0.0282
Mycobacterium tuberculosis Probable peptidase 0.0085 0.0073 0.037
Loa Loa (eye worm) MBOAT family protein 0.0042 0.0015 0.0059
Leishmania major cytochrome p450-like protein 0.0033 0.0004 0.0025
Brugia malayi hypothetical protein 0.0273 0.0321 0.1124
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0053 0.0031 0.0337
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Echinococcus multilocularis peregrin 0.0038 0.001 0.001
Onchocerca volvulus 0.015 0.0158 0.0649
Mycobacterium tuberculosis Probable oxidoreductase 0.0543 0.0677 0.3574
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.1634
Trichomonas vaginalis Importin beta-1 subunit, putative 0.01 0.0092 0.0317
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0088 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0053 0.0031 0.0353
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0365 0.0442 0.1554
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0055 0.0033 0.0112
Echinococcus granulosus pyruvate kinase 0.0032 0.0003 0.0008
Brugia malayi TAR-binding protein 0.0124 0.0124 0.043
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0085 0.0073 0.0602
Echinococcus granulosus glycoprotein Antigen 5 0.0048 0.0023 0.0066
Echinococcus multilocularis hyperpolarization activated cyclic 0.0084 0.0071 0.0071
Brugia malayi orphan nuclear receptor NR2E1 0.0373 0.0453 0.1591
Brugia malayi latrophilin 2 splice variant baaae 0.0524 0.0652 0.2296
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.041 0.0501 0.0501
Brugia malayi putative neuropeptide receptor 0.0101 0.0094 0.0322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0329 0.0394 0.0394
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0659 0.0831 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0071 0.0292
Echinococcus granulosus Niemann Pick C1 protein 0.0208 0.0235 0.0669
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1788 0.2322 0.7688
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.085 0.1084 0.3087
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0055 0.0033 0.0105
Loa Loa (eye worm) hypothetical protein 0.0146 0.0153 0.0636
Schistosoma mansoni hypothetical protein 0.0273 0.0321 0.1059
Onchocerca volvulus Neuropeptide F receptor homolog 0.0101 0.0094 0.0381
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1014 0.1301 0.4588
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0011 0.0035
Schistosoma mansoni P2X receptor subunit 0.0352 0.0426 0.1406
Onchocerca volvulus 0.0101 0.0094 0.0381
Loa Loa (eye worm) hypothetical protein 0.0054 0.0031 0.0124
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0034 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0101 0.0094 0.0307
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Mycobacterium tuberculosis Conserved hypothetical protein 0.0082 0.0069 0.0349
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0085 0.0073 0.0237
Brugia malayi neuropeptide F receptor 0.0101 0.0094 0.0322
Schistosoma mansoni zinc finger protein 0.0042 0.0015 0.0048
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0127 0.0128 0.0449
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0042 0.0015 0.0015
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0013 0.0037
Echinococcus multilocularis conserved hypothetical protein 0.0774 0.0983 0.0983
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0932 0.1191 0.4201
Loa Loa (eye worm) steroid hormone receptor 0.0791 0.1005 0.4194
Schistosoma mansoni neuropeptide receptor 0.0101 0.0094 0.0307
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Plasmodium falciparum importin beta, putative 0.0124 0.0123 0.1456
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0101 0.0094 0.0307
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0932 0.1191 0.4201
Loa Loa (eye worm) hypothetical protein 0.0613 0.0771 0.3216
Echinococcus granulosus Nuclear hormone receptor HR96 0.0373 0.0453 0.129
Brugia malayi Matrixin family protein 0.0739 0.0936 0.3301
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0543 0.0677 0.3574
Brugia malayi steroid hormone receptor 0.0791 0.1005 0.3542
Echinococcus granulosus glutamate synthase 0.0034 0.0005 0.0013
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0659 0.0831 0.2927
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.015 0.0158 0.0158
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0068 0.005 0.0582
Entamoeba histolytica hypothetical protein 0.0188 0.0208 0.0721
Echinococcus granulosus orexin receptor type 2 0.0101 0.0094 0.0267
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Schistosoma mansoni hypothetical protein 0.0034 0.0005 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0229 0.0262 0.201
Loa Loa (eye worm) hypothetical protein 0.0087 0.0074 0.0306
Schistosoma mansoni hypothetical protein 0.0243 0.028 0.0926
Trypanosoma cruzi cAMP binding protein, putative 0.0055 0.0033 0.0112
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0071 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0791 0.1005 0.3542
Schistosoma mansoni opsin-like receptor 0.0101 0.0094 0.0307
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.015 0.0158 0.052
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0949 0.1214 0.4019
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.015 0.0158 0.0554
Loa Loa (eye worm) Smad1 0.0065 0.0046 0.0188
Loa Loa (eye worm) hypothetical protein 0.0269 0.0315 0.1311
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0072 0.0204
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0791 0.1005 0.3542
Plasmodium falciparum diacylglycerol O-acyltransferase 0.025 0.029 0.3469
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0471 0.0582 0.4469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Echinococcus granulosus neuropeptide s receptor 0.0607 0.0763 0.2172
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Trypanosoma brucei glycerol uptake protein, putative 0.0042 0.0015 0.0112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0004 0.0004
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0013 0.003
Onchocerca volvulus 0.0101 0.0094 0.0381
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0034 0.0005 0.0005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.4712
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.015 0.0158 0.1207
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.085 0.1084 0.3586
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0791 0.1005 0.3325
Loa Loa (eye worm) matrix metalloproteinase 0.0739 0.0936 0.3909
Toxoplasma gondii histone lysine methyltransferase SET1 0.0188 0.0209 0.2499
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.156 0.2021 0.7135
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0327 0.0392 0.1295
Toxoplasma gondii thioredoxin reductase 0.0297 0.0353 0.4241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.0449
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Brugia malayi prolyl oligopeptidase family protein 0.0085 0.0073 0.0247
Echinococcus granulosus Niemann Pick C1 protein 0.0297 0.0353 0.1005
Entamoeba histolytica hypothetical protein 0.0042 0.0015 0.0038
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0101 0.0094 0.0387
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1168 0.1504 1
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0091 0.0261
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0055 0.0033 0.0106
Schistosoma mansoni sulfide quinone reductase 0.0034 0.0005 0.0012
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0048 0.0023 0.0066
Loa Loa (eye worm) hypothetical protein 0.015 0.0158 0.0655
Echinococcus multilocularis Mastin 0.0048 0.0023 0.0023
Mycobacterium ulcerans hypothetical protein 0.0048 0.0023 0.0136
Loa Loa (eye worm) hypothetical protein 0.0773 0.0982 0.4098
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0035 0.0007 0.0015
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0052 0.0029 0.0137
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0124 0.0408
Schistosoma mansoni alpha-1 adrenergic receptor 0.0101 0.0094 0.0307
Echinococcus granulosus snurportin 1 0.132 0.1704 0.4854
Brugia malayi hypothetical protein 0.0418 0.0512 0.18
Loa Loa (eye worm) hypothetical protein 0.0395 0.0482 0.201
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Brugia malayi Cytochrome P450 family protein 0.0071 0.0054 0.0181
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.008 0.0065 0.0186
Leishmania major phosphatidylinositol 3-kinase, putative 0.0659 0.0831 0.697
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0127 0.0128 0.0977
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Onchocerca volvulus 0.0739 0.0936 0.3905
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0055 0.0033 0.0159
Echinococcus multilocularis protein dispatched 1 0.0102 0.0095 0.0095
Echinococcus multilocularis serotonin receptor 0.0101 0.0094 0.0094
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0127 0.0128 0.0834
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0034 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0097 0.0088 0.0363
Echinococcus multilocularis acylamino acid releasing enzyme 0.0085 0.0073 0.0073
Plasmodium vivax importin-beta 2, putative 0.0124 0.0123 0.1456
Echinococcus granulosus FTZ F1 alpha 0.0791 0.1005 0.2862
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0208 0.0235 0.0815
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.025 0.029 0.348
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trichomonas vaginalis mercuric reductase, putative 0.0127 0.0128 0.0443
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0042 0.0015 0.0038
Echinococcus multilocularis microtubule associated protein 2 0.1463 0.1893 0.1893
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0072
Loa Loa (eye worm) melatonin receptor type 1A 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.0143 0.0149 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0024 0.0076
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0101 0.0094 0.0307
Onchocerca volvulus 0.0085 0.0072 0.0288
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0019 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0003 0.0017
Trypanosoma brucei target of rapamycin kinase 3, putative 0.015 0.0158 0.1207
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0091 0.03
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Echinococcus multilocularis geminin 0.2316 0.3021 0.3021
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0055 0.0033 0.0378
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.013 0.0132 0.0132
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0034 0.0005 0.0012
Trichomonas vaginalis esterase, putative 0.0229 0.0262 0.0917
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Brugia malayi MBOAT family protein 0.0042 0.0015 0.0045
Schistosoma mansoni hypothetical protein 0.0243 0.028 0.0926
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0096 0.0087 0.1013
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0035 0.0007 0.0015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0097 0.0088 0.0363
Toxoplasma gondii prolyl endopeptidase 0.0085 0.0073 0.0859
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0084 0.0071 0.0202
Mycobacterium ulcerans regulatory protein 0.0055 0.0033 0.0199
Trypanosoma cruzi trypanothione reductase, putative 0.0297 0.0353 0.1244
Mycobacterium ulcerans hypothetical protein 0.009 0.0079 0.0506
Trichomonas vaginalis glutathione reductase, putative 0.0127 0.0128 0.0443
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.008 0.0065 0.0065
Brugia malayi Bromodomain containing protein 0.0161 0.0173 0.0602
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0671 0.0846 0.2986
Echinococcus granulosus lysine specific histone demethylase 1A 0.0082 0.0069 0.0196
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Mycobacterium ulcerans glutaminase 0.0269 0.0316 0.2087
Onchocerca volvulus 0.015 0.0158 0.0649
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0034 0.0005 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0015 0.0042
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0362 0.0438 0.5262
Mycobacterium ulcerans monoamine oxidase 0.0082 0.0069 0.0439
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Schistosoma mansoni bromodomain containing protein 0.0138 0.0142 0.0467
Echinococcus multilocularis serotonin transporter 0.1842 0.2394 0.2394
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0471 0.0582 0.1924
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0034 0.0005 0.0005
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.015 0.0158 0.1207
Chlamydia trachomatis thioredoxin reductase 0.0034 0.0005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0059
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0418 0.0512 0.1458
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0052 0.0029 0.0226
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0236 0.0272 0.1125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.0449
Echinococcus multilocularis orexin receptor type 2 0.0101 0.0094 0.0094
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0006 0.0006
Echinococcus multilocularis lamin 0.0112 0.0108 0.0108
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0055 0.0033 0.0106
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0394 0.0481 0.0481
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0055 0.0033 0.0106
Echinococcus granulosus neuropeptide receptor 0.0101 0.0094 0.0267
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0034 0.0005 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0073 0.0844
Trypanosoma cruzi DNA polymerase kappa, putative 0.0107 0.0101 0.0354
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Loa Loa (eye worm) norepinephrine transporter 0.1842 0.2394 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0892 0.1139 0.6933
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0323 0.0387 0.0387
Echinococcus granulosus neuropeptide Y receptor 0.0101 0.0094 0.0267
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.005 0.0163
Loa Loa (eye worm) DR-78 0.0373 0.0453 0.1887
Brugia malayi Pre-SET motif family protein 0.0065 0.0046 0.0152
Echinococcus multilocularis p2X purinoceptor 4 0.0352 0.0426 0.0426
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.1634
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.017 0.0185 0.061
Mycobacterium ulcerans hypothetical protein 0.0055 0.0033 0.0199
Echinococcus multilocularis 0.0082 0.0069 0.0069
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0106 0.0367
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0115 0.0112 0.0392
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0042 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0791 0.1005 0.3542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Echinococcus multilocularis neuropeptide Y receptor 0.0101 0.0094 0.0094
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0034 0.0005 0.0013
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.015 0.0158 0.045
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0373 0.0453 0.1882
Brugia malayi beta-lactamase family protein 0.0229 0.0262 0.0917
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0029 0.0138
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0055 0.0033 0.0362
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0791 0.1005 0.3325
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Echinococcus granulosus zinc finger protein 0.0049 0.0025 0.007
Mycobacterium tuberculosis Probable lipase LipE 0.0229 0.0262 0.1374
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0023 0.0136
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0048 0.0023 0.0073
Echinococcus granulosus g protein coupled receptor 0.0101 0.0094 0.0267
Loa Loa (eye worm) hypothetical protein 0.0085 0.0073 0.0298
Leishmania major hypothetical protein, conserved 0.021 0.0237 0.1984
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0069 0.0797
Schistosoma mansoni lamin 0.0112 0.0108 0.0355
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.015 0.0158 0.0542
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.015 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus multilocularis allatostatin A receptor 0.0101 0.0094 0.0094
Echinococcus multilocularis Niemann Pick C1 protein 0.0297 0.0353 0.0353
Trichomonas vaginalis transmembrane protein nessy, putative 0.0042 0.0015 0.0045
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0071 0.0232
Brugia malayi RNA, U transporter 1 0.0352 0.0424 0.1491
Brugia malayi Hhat protein 0.0042 0.0015 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Echinococcus granulosus prolyl endopeptidase 0.0085 0.0073 0.0207
Echinococcus granulosus neuropeptides capa receptor 0.0101 0.0094 0.0267
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0011 0.0028
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Leishmania major phosphatidylinositol 3-kinase, putative 0.015 0.0158 0.1318
Brugia malayi ecdysteroid receptor 0.0791 0.1005 0.3542
Brugia malayi G protein-coupled receptor 0.0101 0.0094 0.0322
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.015 0.0158 0.0554
Brugia malayi nuclear hormone receptor family member odr-7 0.0373 0.0453 0.1591
Schistosoma mansoni hypothetical protein 0.0101 0.0094 0.0307
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0005 0.001
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.015 0.0158 0.1207
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0034 0.0005 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0107 0.0101 0.0354
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.015 0.0158 0.045
Loa Loa (eye worm) phosphatidylinositol 3 0.015 0.0158 0.0655
Trichomonas vaginalis bromodomain-containing protein, putative 0.0053 0.0031 0.0099
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0101 0.0094 0.0094
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0101 0.0094 0.0094
Onchocerca volvulus 0.0791 0.1005 0.4191
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.0253
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0035 0.0007 0.0015
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0106 0.0303
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0055 0.0033 0.0105
Treponema pallidum sodium- and chloride- dependent transporter 0.1842 0.2394 1
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0124 0.0408
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0034 0.0005 0.0006
Loa Loa (eye worm) nuclear receptor NHR-67 0.0373 0.0453 0.1887
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.0543 0.2263
Schistosoma mansoni loxhd1 0.0044 0.0018 0.0058
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0077 0.0062 0.0062
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0054 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0091 0.03
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0023 0.0108
Treponema pallidum fructose-bisphosphate aldolase 0.0892 0.1139 0.4747
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0023 0.0066
Trypanosoma cruzi trypanothione reductase, putative 0.0127 0.0128 0.0449
Brugia malayi Serotonin receptor 0.0618 0.0776 0.2733
Onchocerca volvulus 0.0215 0.0244 0.1009
Brugia malayi prolyl oligopeptidase family protein 0.085 0.1084 0.3821
Brugia malayi Serine carboxypeptidase S28 family protein 0.004 0.0013 0.0037
Trichomonas vaginalis glutamate synthase, putative 0.0034 0.0005 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.02 0.0225 0.0741
Echinococcus granulosus intermediate filament protein 0.0112 0.0108 0.0308
Schistosoma mansoni smad1 5 8 and 0.0065 0.0046 0.015
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.2173 0.2832 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Plasmodium vivax ferrodoxin reductase, putative 0.0034 0.0005 0.0022
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0042 0.0015 0.0048
Mycobacterium ulcerans glutamate synthase subunit beta 0.0034 0.0005 0.0012
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0034 0.0005 0.0039
Treponema pallidum catabolite gene activator (Crp) 0.0055 0.0033 0.0118
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.005 0.0315
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0084 0.0071 0.0292
Leishmania major hypothetical protein, conserved 0.0034 0.0005 0.003
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.008 0.0065 0.0496
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0007 0.0053
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Echinococcus granulosus sterol regulatory element binding protein 0.0089 0.0078 0.0222
Loa Loa (eye worm) MBOAT family protein 0.0042 0.0015 0.0059
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.0091 0.0696
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0791 0.1005 0.4194
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0071 0.0232
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0051 0.0027 0.0027
Brugia malayi Cytochrome P450 family protein 0.0033 0.0004 0.0004
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0068 0.005 0.0166
Echinococcus granulosus cGMP dependent protein kinase 1 0.0056 0.0034 0.0098
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0029 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0055 0.0033 0.0112
Treponema pallidum catabolite gene activator 0.0055 0.0033 0.0118
Plasmodium falciparum thioredoxin reductase 0.0127 0.0128 0.1512
Loa Loa (eye worm) hypothetical protein 0.0739 0.0936 0.3909
Schistosoma mansoni hypothetical protein 0.0101 0.0094 0.0307
Schistosoma mansoni cpg binding protein 0.0103 0.0095 0.0313
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0071 0.0232
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0093 0.0083 0.0285
Loa Loa (eye worm) hypothetical protein 0.0739 0.0936 0.3909
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0072 0.0543
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0042 0.0015 0.0048
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0127 0.0128 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Onchocerca volvulus 0.0042 0.0015 0.0053
Plasmodium vivax SET domain protein, putative 0.0065 0.0046 0.0521
Brugia malayi Nuclear hormone receptor-like 1 0.0418 0.0512 0.18
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0085 0.0295
Trypanosoma cruzi cAMP response protein 1 0.0055 0.0033 0.0112
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0092
Mycobacterium ulcerans hypothetical protein 0.0055 0.0033 0.0199
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0096 0.0087 0.0297
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.1014 0.1301 0.4591
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0069 0.0797
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0072
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Leishmania major hypothetical protein, conserved 0.0229 0.0262 0.2194
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0127 0.0128 0.0834
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0088 0.0251
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0031 0.0231
Mycobacterium ulcerans hypothetical protein 0.0353 0.0427 0.2824
Onchocerca volvulus 0.0101 0.0094 0.0381
Brugia malayi MH2 domain containing protein 0.0065 0.0046 0.0153
Onchocerca volvulus Huntingtin homolog 0.0269 0.0315 0.1305
Loa Loa (eye worm) hypothetical protein 0.0739 0.0936 0.3909
Onchocerca volvulus Huntingtin homolog 0.0269 0.0315 0.1305
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0035 0.0007 0.0015
Schistosoma mansoni hypothetical protein 0.0055 0.0033 0.0105
Onchocerca volvulus 0.0048 0.0023 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0013 0.0037
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0373 0.0453 0.1887
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi nuclear receptor RXR 0.0418 0.0512 0.18
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0034 0.0005 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Plasmodium vivax ataxin-2 like protein, putative 0.0125 0.0125 0.1483
Echinococcus multilocularis isocitrate dehydrogenase 0.008 0.0065 0.0065
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0106 0.044
Echinococcus multilocularis Niemann Pick C1 protein 0.0208 0.0235 0.0235
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0773 0.0982 0.3465
Schistosoma mansoni lipoxygenase 0.0194 0.0217 0.0715
Echinococcus granulosus cpg binding protein 0.0103 0.0095 0.0272
Trypanosoma cruzi PAB1-binding protein , putative 0.0125 0.0125 0.044
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.004 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.0185
Trichomonas vaginalis hypothetical protein 0.0035 0.0007 0.0015
Brugia malayi MAP kinase sur-1 0.0111 0.0106 0.0367
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.015 0.0158 0.052
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.0418 0.0512 0.2134
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Echinococcus granulosus enteropeptidase 0.0048 0.0023 0.0066
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.005 0.0587
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.09 0.1149 0.4053
Mycobacterium tuberculosis Probable hydrolase 0.0229 0.0262 0.1374
Schistosoma mansoni terminal deoxycytidyl transferase 0.0077 0.0062 0.0201
Schistosoma mansoni glutamate synthase 0.0034 0.0005 0.0012
Onchocerca volvulus 0.0048 0.0023 0.0086
Echinococcus granulosus Polycystic kidney disease protein 0.0044 0.0018 0.0052
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0892 0.1139 0.4012
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.045 0.0554 0.292
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0023 0.0066
Brugia malayi Trypsin-like protease protein 5 0.0048 0.0023 0.0073
Leishmania major diacylglycerol acyltransferase, putative 0.0406 0.0496 0.4158
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.015 0.0158 0.045
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0071 0.0232
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Onchocerca volvulus Matrilysin homolog 0.0739 0.0936 0.3905
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0034 0.0005 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.0125 0.0125 0.044
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.015 0.0158 0.052
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0065 0.0185
Loa Loa (eye worm) nuclear factor I 0.0036 0.0008 0.0027
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0327 0.0392 0.1117
Giardia lamblia Alanyl dipeptidyl peptidase 0.0085 0.0073 0.0426
Schistosoma mansoni hypothetical protein 0.1048 0.1345 0.445
Onchocerca volvulus 0.0373 0.0453 0.1882
Trypanosoma brucei polo-like protein kinase 0.0097 0.0088 0.0672
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.0005 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0429 0.0527 0.1744
Brugia malayi hypothetical protein 0.0097 0.0088 0.0302
Leishmania major hypothetical protein, conserved 0.0125 0.0125 0.1047
Entamoeba histolytica hypothetical protein 0.0188 0.0208 0.0721
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0471 0.0582 0.0582
Echinococcus granulosus cGMP dependent protein kinase 0.0056 0.0034 0.0098
Toxoplasma gondii target of rapamycin (TOR), putative 0.015 0.0158 0.1887
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.005
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0085 0.0073 0.0241
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.008 0.0065 0.0065
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Schistosoma mansoni diacylglycerol O-acyltransferase 0.009 0.0079 0.0258
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0019 0.0196
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0112 0.0108 0.0447
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0011 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0102 0.0095 0.0391
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0011 0.0011
Echinococcus granulosus thioredoxin glutathione reductase 0.0298 0.0354 0.1008
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Schistosoma mansoni neuropeptide receptor 0.0101 0.0094 0.0307
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0011 0.0053
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0427
Mycobacterium leprae conserved hypothetical protein 0.015 0.0158 0.1353
Brugia malayi RE15519p 0.0101 0.0094 0.0322
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0065 0.0065
Echinococcus multilocularis voltage gated potassium channel 0.012 0.0118 0.0118
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1014 0.1301 0.4584
Echinococcus granulosus histone acetyltransferase KAT2B 0.0161 0.0173 0.0492
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis adenylate cyclase type, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0394 0.0481 0.2003
Schistosoma mansoni neuropeptide f receptor 76f 0.0101 0.0094 0.0307
Treponema pallidum NADH oxidase 0.0127 0.0128 0.0516
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.1765 0.2293 0.7589
Giardia lamblia NADH oxidase lateral transfer candidate 0.0127 0.0128 0.0764
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0033 0.0106
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0471 0.0582 0.2052
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.0039 0.016
Echinococcus multilocularis tar DNA binding protein 0.0124 0.0124 0.0124
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0015 0.0038
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0767 0.0973 0.4061
Brugia malayi G-protein coupled receptor 0.0101 0.0094 0.0322
Brugia malayi Calcitonin receptor-like protein seb-1 0.0767 0.0973 0.3429
Plasmodium falciparum phosphatidylinositol 4-kinase 0.015 0.0158 0.1874
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0013 0.0013
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0034 0.0005 0.0012
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1842 0.2394 0.8452
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0023 0.0136
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0034 0.0005 0.0011
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0505 0.0628 0.3815
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Leishmania major importin beta-1 subunit, putative 0.01 0.0092 0.0769
Brugia malayi hypothetical protein 0.0418 0.0512 0.18
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0068 0.005 0.0286
Schistosoma mansoni smad1 5 8 and 0.0065 0.0046 0.015
Loa Loa (eye worm) inositol-1 0.0038 0.0011 0.004
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0236 0.0272 0.1131
Toxoplasma gondii dgat2l1-prov protein 0.0406 0.0496 0.5963
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.0449
Schistosoma mansoni opsin-like receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi nuclear hormone receptor 0.0791 0.1005 0.3542
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0029 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0327 0.0392 0.4703
Echinococcus multilocularis dna polymerase kappa 0.0107 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi follicle stimulating hormone receptor 0.0326 0.0391 0.1371
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0101 0.0094 0.0094
Echinococcus granulosus nuclear receptor nhr 48 0.0373 0.0453 0.129
Loa Loa (eye worm) phosphatidylinositol 3 0.015 0.0158 0.0655
Echinococcus granulosus neuropeptide FF receptor 2 0.0101 0.0094 0.0267
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0056 0.0034 0.0034
Trypanosoma brucei cAMP response protein 1, putative 0.0055 0.0033 0.0244
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Trichomonas vaginalis ran, putative 0.0068 0.005 0.0166
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0932 0.1191 0.4201
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0057 0.0235
Trypanosoma cruzi protein kinase A regulatory subunit 0.0055 0.0033 0.0112
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Mycobacterium ulcerans dehydrogenase 0.0034 0.0005 0.0012
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0373 0.0453 0.0453
Echinococcus multilocularis neuropeptide FF receptor 2 0.0101 0.0094 0.0094
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0329 0.0394 0.0394
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.015 0.0158 0.0554
Schistosoma mansoni sodium/chloride dependent transporter 0.0328 0.0394 0.1301
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Toxoplasma gondii isocitrate dehydrogenase 0.008 0.0065 0.0773
Trypanosoma brucei unspecified product 0.0053 0.003 0.0225
Echinococcus multilocularis neuropeptide receptor A26 0.0607 0.0763 0.0763
Mycobacterium ulcerans transmembrane transport protein 0.0055 0.0033 0.0199
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0004 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0748 0.0949 0.3138
Giardia lamblia DINP protein human, muc B family 0.0084 0.0072 0.042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0373 0.0453 0.129
Echinococcus multilocularis expressed conserved protein 0.0195 0.0218 0.0218
Schistosoma mansoni P2X receptor subunit 0.0207 0.0233 0.077
Echinococcus granulosus g protein coupled receptor 0.0101 0.0094 0.0267
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0791 0.1005 0.2862
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0791 0.1005 0.2862
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0427
Onchocerca volvulus 0.1842 0.2394 1
Schistosoma mansoni sterol O-acyltransferase 1 0.0042 0.0015 0.0048
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.4712
Brugia malayi Pip kinase protein 2 0.0323 0.0387 0.136
Leishmania major protein kinase A regulatory subunit, putative 0.0055 0.0033 0.0267
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0077 0.0062 0.0201
Schistosoma mansoni smad1 5 8 and 0.0065 0.0046 0.015
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0327 0.0392 0.1117
Echinococcus granulosus somatostatin receptor 0.0101 0.0094 0.0267
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Treponema pallidum cyclic nucleotide binding protein 0.0055 0.0033 0.0118
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.015 0.0158 0.0158
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0085 0.0073 0.0237
Trypanosoma cruzi GUP1, putative 0.0042 0.0015 0.0051
Brugia malayi prolyl oligopeptidase family protein 0.0085 0.0073 0.0247
Echinococcus granulosus neuropeptide Y receptor 0.0101 0.0094 0.0267
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Leishmania major phosphomannose isomerase 0.0096 0.0087 0.072
Onchocerca volvulus 0.0112 0.0108 0.0441
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0427
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0406 0.0496 0.1639
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0084 0.0072 0.0593
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.085 0.1084 0.452
Echinococcus granulosus microtubule associated protein 2 0.1463 0.1893 0.5392
Brugia malayi hypothetical protein 0.0327 0.0392 0.1376
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0082 0.0069 0.0224
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0436 0.0536 0.4649
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.009 0.0079 0.0275
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0082 0.0069 0.0575
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus granulosus serine:threonine protein kinase SMG1 0.015 0.0158 0.045
Brugia malayi hypothetical protein 0.0081 0.0067 0.0227
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0327 0.0392 0.1295
Schistosoma mansoni sodium/chloride dependent transporter 0.1842 0.2394 0.7925
Schistosoma mansoni hypothetical protein 0.0188 0.0208 0.0687
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0023 0.0136
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.0062 0.0313
Schistosoma mansoni hypothetical protein 0.0086 0.0074 0.0241
Toxoplasma gondii FATC domain-containing protein 0.015 0.0158 0.1887
Mycobacterium ulcerans hypothetical protein 0.0055 0.0033 0.0199
Giardia lamblia Phosphatidylinositol 4-kinase 0.015 0.0158 0.0947
Schistosoma mansoni disulfide oxidoreductase 0.0034 0.0005 0.0012
Onchocerca volvulus 0.0044 0.0018 0.0066
Echinococcus multilocularis ecdysone induced protein 78C 0.0791 0.1005 0.1005
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0055 0.0033 0.0244
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0543 0.0677 0.5884
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0084 0.0071 0.0202
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0023
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0034 0.0005 0.0039
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0101 0.0094 0.0267
Loa Loa (eye worm) hypothetical protein 0.0273 0.0321 0.1335
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0106 0.0812
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Echinococcus granulosus muscleblind protein 0.0146 0.0153 0.0437
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0327 0.0392 0.1295
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0055 0.0033 0.0105
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0056 0.0034 0.0399
Plasmodium falciparum ataxin-2 like protein, putative 0.0125 0.0125 0.1483
Schistosoma mansoni chromobox protein 0.0074 0.0057 0.0187
Loa Loa (eye worm) prolyl oligopeptidase 0.0085 0.0073 0.0298
Echinococcus granulosus patatin phospholipase domain containing protein 0.0055 0.0033 0.0093
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Brugia malayi MBOAT family protein 0.0042 0.0015 0.0045
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0065 0.0768
Loa Loa (eye worm) hypothetical protein 0.0125 0.0125 0.0519
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0106 0.0373
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0045
Echinococcus granulosus biogenic amine 5HT receptor 0.0101 0.0094 0.0267
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.0124 0.0514
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0791 0.1005 0.1005
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.015 0.0158 0.0554
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Brugia malayi N-terminal motif family protein 0.0236 0.0272 0.0951
Echinococcus multilocularis neuropeptides capa receptor 0.0101 0.0094 0.0094
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.008 0.0065 0.0065
Loa Loa (eye worm) programmed cell death 8 0.0034 0.0005 0.0014
Brugia malayi acetyltransferase, GNAT family protein 0.017 0.0185 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0046 0.0149
Loa Loa (eye worm) hypothetical protein 0.0183 0.0201 0.0836
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.015 0.0158 0.1887
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0006 0.0017
Echinococcus multilocularis GPCR, family 2 0.0243 0.028 0.028
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0006 0.0016
Schistosoma mansoni biogenic amine (5HT) receptor 0.0101 0.0094 0.0307
Leishmania major hypothetical protein, conserved 0.0042 0.0015 0.0122
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0082 0.0069 0.0224
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0106 0.1267
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.1376
Echinococcus multilocularis thyroid hormone receptor alpha 0.0791 0.1005 0.1005
Trichomonas vaginalis penicillin-binding protein, putative 0.0229 0.0262 0.0917
Leishmania major DNA polymerase eta, putative 0.0106 0.0099 0.0828
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0088 0.0358
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0042 0.0015 0.0015
Echinococcus multilocularis G protein coupled receptor 139 0.0101 0.0094 0.0094
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0096 0.0087 0.0087
Brugia malayi Bromodomain containing protein 0.0082 0.0068 0.023
Trichomonas vaginalis importin beta-1, putative 0.01 0.0092 0.0317
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0373 0.0453 0.1497
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0297 0.0353 0.1856
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0106 0.0367
Mycobacterium ulcerans NADH dehydrogenase 0.0034 0.0005 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0773 0.0982 0.346
Echinococcus multilocularis dro:myosuppressin receptor 0.0101 0.0094 0.0094
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0001 0.0003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0101 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.005
Schistosoma mansoni steroid hormone receptor ad4bp 0.0791 0.1005 0.3325
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Loa Loa (eye worm) phosphatidylinositol kinase 0.015 0.0158 0.0655
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0423 0.0518 0.6236
Leishmania major phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.1318
Brugia malayi ORL1-like opioid receptor 0.0101 0.0094 0.0322
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0011 0.0028
Trypanosoma brucei NADH dehydrogenase 0.0034 0.0005 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Schistosoma mansoni sulfide quinone reductase 0.0034 0.0005 0.0012
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0932 0.1191 0.9159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Echinococcus multilocularis pyruvate kinase 0.0032 0.0003 0.0003
Echinococcus granulosus single minded 2 0.0035 0.0007 0.0019
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0229 0.0262 0.1728
Schistosoma mansoni hypothetical protein 0.0243 0.028 0.0926
Trypanosoma brucei glycerol uptake protein, putative 0.0042 0.0015 0.0112
Brugia malayi Trypsin family protein 0.0048 0.0023 0.0073
Entamoeba histolytica hypothetical protein 0.015 0.0158 0.0542
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0034 0.0005 0.0013
Schistosoma mansoni amine GPCR 0.0101 0.0094 0.0307
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0096 0.0087 0.1013
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.015 0.0158 0.1318
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0791 0.1005 0.3542
Entamoeba histolytica protein kinase rad3, putative 0.015 0.0158 0.0542
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0418 0.0512 0.2134
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Brugia malayi sulfakinin receptor protein 0.0101 0.0094 0.0322
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.008 0.0065 0.0228
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Mycobacterium ulcerans oxidoreductase 0.0082 0.0069 0.0439
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0033 0.0159
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0932 0.1191 0.4205
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0088 0.0308
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0791 0.1005 0.1005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.005 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Schistosoma mansoni amine GPCR 0.0101 0.0094 0.0307
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0011 0.0022
Echinococcus granulosus g-protein coupled receptor 0.0101 0.0094 0.0267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0004 0.0004
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0042 0.0015 0.0015
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0082 0.0069 0.0797
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0004 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Echinococcus multilocularis sterol regulatory element binding protein 0.0089 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0934 0.1194 0.421
Trypanosoma brucei Flagellar Member 6 0.0055 0.0033 0.0244
Echinococcus granulosus transmembrane protease serine 3 0.0048 0.0023 0.0066
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.009 0.0079 0.0275
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Loa Loa (eye worm) hypothetical protein 0.01 0.0091 0.0377
Onchocerca volvulus Protein ultraspiracle homolog 0.0791 0.1005 0.4191
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0038 0.0155
Trypanosoma brucei phosphomannose isomerase 0.0096 0.0087 0.0659
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0085 0.0073 0.0247
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0085 0.0073 0.0551
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0135 0.0445
Loa Loa (eye worm) hypothetical protein 0.0105 0.0099 0.041
Schistosoma mansoni voltage-gated potassium channel 0.012 0.0118 0.0387
Toxoplasma gondii hypothetical protein 0.0327 0.0392 0.4712
Brugia malayi Intermediate filament tail domain containing protein 0.0112 0.0108 0.0373
Echinococcus granulosus mannose 6 phosphate isomerase 0.0096 0.0087 0.0247
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0034 0.0005 0.0012
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.0005 0.0006
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0007 0.0113
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.2173 0.2832 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0048 0.0023 0.0066
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0084 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0153 0.0153
Leishmania major UDP-galactopyranose mutase 0.0082 0.0069 0.0569
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0055 0.0033 0.0362
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.1874
Brugia malayi MBOAT family protein 0.0042 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0106 0.0099 0.0411
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0015 0.0049
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0055 0.0033 0.0093
Toxoplasma gondii hypothetical protein 0.0085 0.0073 0.0859
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0011 0.0082
Brugia malayi beta-lactamase 0.0229 0.0262 0.0917
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0327 0.0392 0.0392
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.0122
Loa Loa (eye worm) hypothetical protein 0.0089 0.0078 0.0321
Schistosoma mansoni pyruvate kinase 0.0032 0.0003 0.0006
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0034 0.0005 0.0028
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.015 0.0158 0.045
Echinococcus granulosus expressed conserved protein 0.0195 0.0218 0.0622
Toxoplasma gondii diacylglycerol acyltransferase 0.009 0.0079 0.0933
Echinococcus granulosus serotonin transporter 0.1842 0.2394 0.6819
Echinococcus granulosus lysine specific demethylase 5A 0.0102 0.0095 0.027
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0029 0.0082
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0042 0.0015 0.0044
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1086 0.1395 0.7376
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0932 0.1191 0.4974
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0035 0.0007 0.0015
Brugia malayi MH1 domain containing protein 0.0065 0.0046 0.0153
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0327 0.0392 0.1117
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0018 0.0018
Mycobacterium tuberculosis Conserved protein 0.0055 0.0033 0.0159
Onchocerca volvulus 0.0044 0.0018 0.0066
Schistosoma mansoni hypothetical protein 0.2316 0.3021 1
Loa Loa (eye worm) pip kinase 2 0.0323 0.0387 0.1614
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.0237 0.0834
Echinococcus granulosus geminin 0.2316 0.3021 0.8604
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.0415
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0082 0.0069 0.0069
Echinococcus granulosus g protein coupled receptor 0.0101 0.0094 0.0267
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0023 0.0072
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0327 0.0392 0.1295
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0001 0.0001
Echinococcus granulosus tar DNA binding protein 0.0124 0.0124 0.0354
Schistosoma mansoni rab6-interacting 0.0044 0.0018 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0005 0.001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0035 0.0007 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.005 0.0163
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0055 0.0033 0.0159
Schistosoma mansoni hypothetical protein 0.133 0.1718 0.5686
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0791 0.1005 0.3542
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.012 0.0118 0.0407
Schistosoma mansoni Smad4 0.0065 0.0046 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0088 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.004 0.03
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0004 0.0004
Echinococcus granulosus ecdysone induced protein 78C 0.0791 0.1005 0.2862
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0229 0.0262 0.0865
Schistosoma mansoni biogenic amine receptor 0.0101 0.0094 0.0307
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0127 0.0128 0.0364
Schistosoma mansoni patched 1 0.0089 0.0078 0.0255
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Echinococcus multilocularis chromobox protein 1 0.0074 0.0057 0.0057
Echinococcus multilocularis somatostatin receptor 0.0101 0.0094 0.0094
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0055 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.1091
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0055 0.0033 0.0093
Trypanosoma brucei unspecified product 0.0053 0.003 0.0225
Plasmodium falciparum ferrodoxin reductase-like protein 0.0034 0.0005 0.0022
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1014 0.1301 0.4584
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0055 0.0033 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0023 0.0178
Mycobacterium ulcerans ferredoxin reductase 0.0034 0.0005 0.0012
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.004 0.0114
Loa Loa (eye worm) hypothetical protein 0.0124 0.0123 0.051
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.015 0.0158 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0078 0.0266
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0127 0.0128 0.0443
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0027
Echinococcus multilocularis 0.015 0.0158 0.0158
Echinococcus granulosus Mastin 0.0048 0.0023 0.0066
Brugia malayi Nuclear hormone receptor E75 0.0373 0.0453 0.1591
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Trypanosoma cruzi DNA polymerase eta, putative 0.0106 0.0099 0.0348
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0053 0.0031 0.0353
Echinococcus granulosus dro:myosuppressin receptor 0.0101 0.0094 0.0267
Mycobacterium ulcerans monoxygenase 0.0034 0.0005 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Brugia malayi diacylglycerol acyltransferase family protein 0.0406 0.0496 0.1743
Giardia lamblia Alanyl dipeptidyl peptidase 0.0085 0.0073 0.0426
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Schistosoma mansoni thyroid hormone receptor 0.0791 0.1005 0.3325
Mycobacterium ulcerans transcriptional regulatory protein 0.0055 0.0033 0.0199
Echinococcus multilocularis lysine specific demethylase 5A 0.0093 0.0083 0.0083
Echinococcus multilocularis neuropeptide receptor 0.0101 0.0094 0.0094
Loa Loa (eye worm) MH2 domain-containing protein 0.0957 0.1225 0.5114
Schistosoma mansoni nuclear hormone receptor 0.0791 0.1005 0.3325
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Loa Loa (eye worm) matrixin family protein 0.1639 0.2126 0.888
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1014 0.1301 0.4588
Echinococcus multilocularis mothers against decapentaplegic 5 0.0065 0.0046 0.0046
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0077 0.0062 0.0176
Echinococcus multilocularis neuropeptide Y receptor 0.0101 0.0094 0.0094
Toxoplasma gondii selenide, water dikinase 0.0034 0.0005 0.0039
Schistosoma mansoni zinc finger protein 0.0373 0.0453 0.1497
Schistosoma mansoni myosin xvIII 0.0101 0.0094 0.0307
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0042 0.0015 0.0048
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.025 0.029 0.0957
Brugia malayi Matrixin family protein 0.0739 0.0936 0.3301
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.1765 0.2293 0.6531
Trypanosoma brucei oligopeptidase b 0.0085 0.0073 0.0551
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0032 0.011
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1014 0.1301 0.4304
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0055 0.0033 0.0105
Trypanosoma brucei protein kinase, putative 0.0111 0.0106 0.0812
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0035 0.0007 0.0015
Brugia malayi Matrixin family protein 0.0739 0.0936 0.3301
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0127 0.0128 0.0663
Brugia malayi polk-prov protein 0.0054 0.0031 0.01
Onchocerca volvulus 0.0077 0.0062 0.0247
Trypanosoma cruzi NADH dehydrogenase, putative 0.0034 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.1765 0.2293 0.9577
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0034 0.0005 0.0005
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0082 0.0069 0.0797
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0023 0.0186
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0068 0.005 0.005
Brugia malayi Isocitrate dehydrogenase 0.008 0.0065 0.0222
Trypanosoma cruzi DNA polymerase kappa, putative 0.0107 0.0101 0.0354
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0373 0.0453 0.0453
Echinococcus multilocularis neuropeptide s receptor 0.0607 0.0763 0.0763
Echinococcus multilocularis lamin dm0 0.0112 0.0108 0.0108
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0243 0.028 0.028
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0101 0.0094 0.0387
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0068 0.005 0.0567
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0042 0.0015 0.0059
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0127 0.0128 0.1527
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0011 0.0028
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0057 0.0193
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0055 0.0033 0.0362
Mycobacterium tuberculosis Putative ferredoxin reductase 0.045 0.0554 0.292
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0127 0.0128 0.1512
Onchocerca volvulus 0.0101 0.0094 0.0381
Echinococcus multilocularis FTZ F1 alpha 0.0791 0.1005 0.1005
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0052 0.018
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0034 0.0005 0.0006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0101 0.0094 0.0094
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.004 0.0013 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0791 0.1005 0.3542
Echinococcus granulosus dna polymerase eta 0.0106 0.0099 0.0283
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0065 0.0753
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0004 0.0004
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0659 0.0831 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0069 0.0282
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0023 0.0108
Loa Loa (eye worm) hypothetical protein 0.0194 0.0217 0.09
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0051 0.0027 0.0088
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0023 0.0186
Leishmania major GTP-binding protein, putative 0.0068 0.005 0.0409
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.015 0.0158 0.1207
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0055 0.0033 0.0244
Schistosoma mansoni hypothetical protein 0.015 0.0158 0.052
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0127 0.0128 0.1067
Brugia malayi hypothetical protein 0.0269 0.0315 0.1103
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.3784 0.4961 1
Schistosoma mansoni mannose-6-phosphate isomerase 0.0096 0.0087 0.0284
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0107 0.0101 0.0348
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0188 0.0208 0.0208
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0034 0.0005 0.0013
Echinococcus multilocularis fmrfamide receptor 0.0101 0.0094 0.0094
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1204 0.1551 0.5471
Onchocerca volvulus 0.0048 0.0023 0.0086
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0031 0.0031
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0035 0.0007 0.0015
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0034 0.0005 0.0022
Onchocerca volvulus 0.0229 0.0262 0.1085
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0055 0.0033 0.0378
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0932 0.1191 1
Loa Loa (eye worm) hypothetical protein 0.0934 0.1194 0.4984
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0106 0.0106
Loa Loa (eye worm) MH2 domain-containing protein 0.0065 0.0046 0.0188
Loa Loa (eye worm) hypothetical protein 0.0146 0.0153 0.0636
Schistosoma mansoni phosphatidylinositol 4-kinase 0.015 0.0158 0.052
Loa Loa (eye worm) hypothetical protein 0.0339 0.0408 0.17
Schistosoma mansoni voltage-gated potassium channel 0.0429 0.0527 0.1744
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.008 0.0065 0.0757
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0329 0.0394 0.1123
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0035 0.0007 0.0015
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Leishmania major cyclic nucleotide-binding protein-like protein 0.0055 0.0033 0.0267
Echinococcus multilocularis pyruvate kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis glycoprotein Antigen 5 0.0048 0.0023 0.0023
Schistosoma mansoni lipoxygenase 0.0115 0.0111 0.0366
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.0262 0.0923
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.015 0.0158 0.0548
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.1091
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0085 0.0073 0.0237
Trichomonas vaginalis glutamate synthase, putative 0.0034 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0025
Echinococcus granulosus dna polymerase kappa 0.0107 0.0101 0.0288
Trichomonas vaginalis adenylate cyclase type, putative 0.0035 0.0007 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi hypothetical protein 0.0373 0.0453 0.1591
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.015 0.0158 0.1874
Loa Loa (eye worm) phosphatidylinositol 3 0.0865 0.1103 0.4604
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.005 0.0412
Brugia malayi Dopamine receptor 0.0101 0.0094 0.0322
Trypanosoma brucei importin beta-1 subunit, putative 0.0124 0.0123 0.0942
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0089 0.0078 0.0321
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Schistosoma mansoni voltage-gated potassium channel 0.0065 0.0045 0.0147
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0317 0.0379 0.3179
Onchocerca volvulus 0.0048 0.0023 0.0086
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Echinococcus granulosus acylamino acid releasing enzyme 0.0085 0.0073 0.0207
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0471 0.0582 0.2052
Schistosoma mansoni DNA polymerase eta 0.0106 0.0099 0.0326
Leishmania major hypothetical protein, unknown function 0.0055 0.0033 0.0267
Trichomonas vaginalis glutaminase, putative 0.0269 0.0316 0.1108
Mycobacterium leprae conserved hypothetical protein 0.0229 0.0262 0.2263
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0055 0.0033 0.0106
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.2173 0.2832 1
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0659 0.0831 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0127 0.0128 0.0977
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0082 0.0069 0.0439
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0101 0.0094 0.0267
Brugia malayi CHE-14 protein 0.0089 0.0078 0.0266
Brugia malayi Dopamine receptor protein 1 0.0101 0.0094 0.0322
Brugia malayi GnHR receptor homolog 0.0101 0.0094 0.0322
Trypanosoma brucei prolyl oligopeptidase, putative 0.0085 0.0073 0.0551
Loa Loa (eye worm) glutaminase 2 0.0269 0.0316 0.1316
Leishmania major phosphatidylinositol kinase, putative 0.015 0.0158 0.1318
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.2687 0.3511 1
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0052 0.018
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Schistosoma mansoni smad 0.0065 0.0046 0.015
Giardia lamblia Serine peptidase, putative 0.004 0.0013 0.0063
Loa Loa (eye worm) AGC/PKG protein kinase 0.0056 0.0034 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Brugia malayi RNA binding protein 0.0124 0.0124 0.043
Trypanosoma brucei cAMP binding protein, putative 0.0055 0.0033 0.0244
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0065 0.0046 0.015
Onchocerca volvulus 0.0101 0.0094 0.0381
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0101 0.0094 0.0322
Trichomonas vaginalis adenylate cyclase type III, putative 0.0035 0.0007 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.009 0.0079 0.0275
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.015 0.0158 0.0554
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0085 0.0073 0.0602
Trypanosoma brucei DNA polymerase IV, putative 0.0107 0.0101 0.0771
Brugia malayi hypothetical protein 0.1054 0.1352 0.477
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0373 0.0453 0.0453
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0101 0.0094 0.0322
Schistosoma mansoni kinase 0.005 0.0026 0.0082
Plasmodium falciparum glutathione reductase 0.0297 0.0353 0.4231
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.008 0.0065 0.0214
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1461 0.1891 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.0449
Mycobacterium tuberculosis Probable reductase 0.045 0.0554 0.292
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Echinococcus granulosus cGMP dependent protein kinase 1 0.0056 0.0034 0.0098
Mycobacterium ulcerans DNA polymerase IV 0.0107 0.0101 0.0656
Brugia malayi hypothetical protein 0.0044 0.0018 0.0056
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0323 0.0387 0.128
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0052 0.018
Echinococcus granulosus peptide allatostatin:somatostatin 0.0101 0.0094 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Onchocerca volvulus 0.0323 0.0387 0.1609
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0034 0.0005 0.003
Echinococcus multilocularis muscleblind protein 0.0146 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.1842 0.2394 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0055 0.0033 0.0159
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.013 0.0132 0.0377
Schistosoma mansoni retinoic acid receptor RXR 0.0791 0.1005 0.3325
Loa Loa (eye worm) diacylglycerol acyltransferase 0.025 0.029 0.1207
Trichomonas vaginalis set domain proteins, putative 0.0502 0.0623 0.2192
Brugia malayi chromobox protein homolog 3 0.0041 0.0015 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Trichomonas vaginalis porcupine, putative 0.0042 0.0015 0.0045
Echinococcus granulosus smad 0.0065 0.0046 0.0131
Schistosoma mansoni jumonji/arid domain-containing protein 0.0102 0.0095 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0065 0.0046 0.0046
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0057 0.0193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0329 0.0394 0.1302
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0091 0.0091
Entamoeba histolytica deoxycytidyl transferase, putative 0.0077 0.0062 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0791 0.1005 0.4194
Loa Loa (eye worm) TAR-binding protein 0.0124 0.0124 0.0514
Leishmania major trypanothione reductase 0.0297 0.0353 0.2958
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0005 0.0013
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.0237 0.0834
Onchocerca volvulus 0.0101 0.0094 0.0381
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.015 0.0158 0.1887
Trypanosoma brucei prolyl endopeptidase 0.0085 0.0073 0.0551
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0005 0.0023
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0791 0.1005 0.3325
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0052 0.018
Echinococcus multilocularis fmrfamide receptor 0.0101 0.0094 0.0094
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0023 0.0178
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0048 0.0023 0.0074
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0034 0.0005 0.0005
Onchocerca volvulus 0.0229 0.0262 0.1085
Leishmania major pyruvate kinase 0.0032 0.0003 0.0015
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0034 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0034 0.0005 0.0016
Loa Loa (eye worm) CXXC zinc finger family protein 0.0093 0.0083 0.0343
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0065 0.0544
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0005 0.0014
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0055 0.0033 0.0378
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0671 0.0846 0.2986
Brugia malayi jmjC domain containing protein 0.0102 0.0095 0.0325
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Giardia lamblia Thymus-specific serine protease precursor 0.004 0.0013 0.0063
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2173 0.2832 1
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Brugia malayi prolyl oligopeptidase family protein 0.0085 0.0073 0.0247
Echinococcus granulosus lysine specific histone demethylase 1A 0.0082 0.0069 0.0196
Loa Loa (eye worm) hhat protein 0.0042 0.0015 0.0059
Echinococcus multilocularis hyperpolarization activated cyclic 0.0084 0.0071 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0229 0.0262 0.0917
Loa Loa (eye worm) intermediate filament protein 0.0112 0.0108 0.0447
Loa Loa (eye worm) solute carrier family 6 member 4 0.1842 0.2394 1
Echinococcus multilocularis g protein coupled receptor 0.0101 0.0094 0.0094
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0101 0.0094 0.0094
Trypanosoma brucei PAB1-binding protein , putative 0.0125 0.0125 0.0959
Mycobacterium ulcerans lipase LipD 0.0229 0.0262 0.1728
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0791 0.1005 0.2862
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0932 0.1191 0.4198
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0791 0.1005 0.4191
Echinococcus granulosus Smad4 0.0065 0.0046 0.0131
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.015 0.0158 0.1318
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0101 0.0094 0.0094
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0106 0.0373
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.015 0.0158 0.045
Brugia malayi nuclear receptor RXR 0.0373 0.0453 0.1591
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0127 0.0128 0.0449
Trypanosoma brucei isocitrate dehydrogenase, putative 0.008 0.0065 0.0496
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0194 0.0217 0.0617
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0092
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0056 0.0034 0.0034
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0003 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.045 0.0554 0.292
Echinococcus granulosus Nuclear hormone receptor HR96 0.0373 0.0453 0.129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0791 0.1005 0.4194
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0056 0.0034 0.0097
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0327 0.0392 1
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0055 0.0033 0.0106
Schistosoma mansoni transcription factor LCR-F1 0.0188 0.0208 0.0687
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0085 0.0073 0.0609
Onchocerca volvulus Bile acid receptor homolog 0.0791 0.1005 0.4191
Schistosoma mansoni nuclear hormone receptor 0.0373 0.0453 0.1497
Schistosoma mansoni zinc finger protein 0.0049 0.0025 0.0079
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus granulosus Dipeptidyl peptidase 9 0.0471 0.0582 0.1657
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0006 0.0016
Loa Loa (eye worm) RNA binding protein 0.0124 0.0124 0.0514
Entamoeba histolytica hypothetical protein 0.015 0.0158 0.0542
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.004 0.0013 0.004
Brugia malayi GNT-I family protein 0.0105 0.0099 0.0341
Schistosoma mansoni alpha-13-mannosyl-glycoprotein beta-1 2-n-acetylglucosaminyltransferase 0.0105 0.0099 0.0325
Loa Loa (eye worm) hypothetical protein 0.012 0.0118 0.0488
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0093 0.0083 0.0285
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0034 0.0005 0.0039
Brugia malayi glutathione reductase 0.0297 0.0353 0.1238
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0033 0.0159
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0101 0.0094 0.0381
Plasmodium falciparum cGMP-dependent protein kinase 0.0056 0.0034 0.0382
Brugia malayi MH2 domain containing protein 0.0957 0.1225 0.4319
Brugia malayi Cytochrome P450 family protein 0.0033 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0932 0.1191 0.1191
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.0449
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0011 0.0113
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0042 0.0015 0.0044
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0101 0.0094 0.0387
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Brugia malayi Serotonin receptor 0.0101 0.0094 0.0322
Loa Loa (eye worm) MH1 domain-containing protein 0.0065 0.0046 0.0188
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0243 0.028 0.0799
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0034 0.0111
Toxoplasma gondii HEAT repeat-containing protein 0.0124 0.0123 0.1471
Plasmodium falciparum thioredoxin reductase 0.0297 0.0353 0.4231
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Brugia malayi hypothetical protein 0.0373 0.0453 0.1591
Schistosoma mansoni fkbp-rapamycin associated protein 0.015 0.0158 0.052
Echinococcus multilocularis prolyl endopeptidase 0.0085 0.0073 0.0073
Brugia malayi G protein-coupled receptor F59B2.13 0.0101 0.0094 0.0322
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Onchocerca volvulus 0.0082 0.0069 0.0276
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.009 0.0079 0.0598
Plasmodium falciparum transporter, putative 0.0327 0.0392 0.4703
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0055 0.0033 0.0105
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0055 0.0033 0.0378
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.1091
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0323 0.0387 0.128
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0243 0.028 0.0982
Leishmania major hypothetical protein, conserved 0.0034 0.0005 0.003
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0096 0.0087 0.0297
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0373 0.0453 0.0453
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0055 0.0033 0.0769
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0273 0.0321 0.1129
Loa Loa (eye worm) phosphatidylinositol 3 0.015 0.0158 0.0655
Leishmania major hypothetical protein, conserved 0.0034 0.0005 0.003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.005 0.025
Echinococcus granulosus survival motor neuron protein 1 0.1054 0.1352 0.3852
Loa Loa (eye worm) thioredoxin reductase 0.0297 0.0353 0.1471
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0106 0.0367
Loa Loa (eye worm) glutathione reductase 0.0297 0.0353 0.1471
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0034 0.0005 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0106 0.0303
Echinococcus granulosus pyruvate kinase 0.0032 0.0003 0.0008
Brugia malayi Doublecortin family protein 0.0044 0.0018 0.0056
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.0039 0.013
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Schistosoma mansoni eyes absent homolog 0.0097 0.0088 0.0289
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Echinococcus granulosus importin subunit beta 1 0.0124 0.0123 0.0351
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0323 0.0387 0.1103
Trypanosoma cruzi oligopeptidase b 0.0085 0.0073 0.0253
Echinococcus granulosus thyroid hormone receptor alpha 0.0373 0.0453 0.129
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.1765 0.2293 0.2293
Echinococcus granulosus fmrfamide receptor 0.0101 0.0094 0.0267
Mycobacterium ulcerans hydrolase 0.09 0.1149 0.7638
Brugia malayi nuclear hormone receptor family member nhr-6 0.0373 0.0453 0.1591
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0034 0.0005 0.0022
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0018 0.0052
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0055 0.0033 0.0033
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0006 0.0016
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0471 0.0582 0.4469
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0791 0.1005 0.3542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Plasmodium vivax multidomain scavenger receptor, putative 0.0044 0.0018 0.019
Mycobacterium tuberculosis Conserved hypothetical protein 0.015 0.0158 0.0822
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0034 0.0005 0.0028
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0034 0.0005 0.001
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0034 0.0005 0.0006
Onchocerca volvulus 0.0101 0.0094 0.0381
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0106 0.0349
Entamoeba histolytica hypothetical protein, conserved 0.0085 0.0073 0.0241
Leishmania major hypothetical protein, unknown function,protein, unknown function 0.009 0.0079 0.0653
Treponema pallidum alginate O-acetylation protein (algI) 0.0042 0.0015 0.0046
Schistosoma mansoni biogenic amine receptor 0.0101 0.0094 0.0307
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0034 0.0005 0.0012
Plasmodium vivax glutathione reductase, putative 0.0297 0.0353 0.4231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0329 0.0394 0.1302
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0034 0.0005 0.0012
Trypanosoma cruzi importin beta-1 subunit, putative 0.01 0.0092 0.0323
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.2173 0.2832 0.9375
Trypanosoma cruzi UDP-galactopyranose mutase 0.0082 0.0069 0.0239
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.017 0.0185 0.0185
Entamoeba histolytica hypothetical protein 0.1818 0.2362 0.8338
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.2687 0.3511 0.3511
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0034 0.0005 0.0039
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.156 0.2021 0.5757
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0084 0.0071 0.0202
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Brugia malayi nuclear hormone receptor 0.0373 0.0453 0.1591
Plasmodium vivax amine transporter, putative 0.0327 0.0392 0.4703
Brugia malayi jmjC domain containing protein 0.0152 0.0161 0.0559
Trichomonas vaginalis penicillin-binding protein, putative 0.0229 0.0262 0.0917
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0085 0.0073 0.037
Plasmodium vivax thioredoxin reductase, putative 0.0297 0.0353 0.4231
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.132 0.1704 0.7116
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0055 0.0033 0.0112
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.015 0.0158 0.0548
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0101 0.0094 0.0307
Brugia malayi hypothetical protein 0.0048 0.0023 0.0073
Echinococcus multilocularis expressed conserved protein 0.0056 0.0034 0.0034
Leishmania major glycerol uptake protein, putative 0.0042 0.0015 0.0122
Brugia malayi diacylglycerol acyltransferase 0.025 0.029 0.1015
Schistosoma mansoni polycystin 1-related 0.0377 0.0458 0.1514
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.09 0.1149 0.6073
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.1207
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi MH1 domain containing protein 0.0036 0.0008 0.0017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0791 0.1005 0.1005
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0033 0.0112
Trypanosoma cruzi UDP-galactopyranose mutase 0.0082 0.0069 0.0239
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0365 0.0442 0.1554
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0055 0.0033 0.0106
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.1091
Brugia malayi tailless protein 0.0373 0.0453 0.1591
Trypanosoma cruzi Flagellar Member 6 0.0055 0.0033 0.0112
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0023 0.0074
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0023 0.0136
Echinococcus granulosus lamin 0.0112 0.0108 0.0308
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0659 0.0831 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0229 0.0262 0.1091
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Loa Loa (eye worm) hypothetical protein 0.0418 0.0512 0.2134
Onchocerca volvulus 0.0101 0.0094 0.0381
Brugia malayi hypothetical protein 0.0125 0.0125 0.0434
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Brugia malayi Cyclic-nucleotide gated cation channel 0.0084 0.0071 0.0241
Echinococcus granulosus hyperpolarization activated cyclic 0.0084 0.0071 0.0202
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0748 0.0949 0.0949
Schistosoma mansoni P2X receptor subunit 0.0352 0.0426 0.1406
Schistosoma mansoni coup transcription factor 0.0791 0.1005 0.3325
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0042 0.0015 0.0044
Onchocerca volvulus 0.0101 0.0094 0.0381
Schistosoma mansoni importin beta-1 0.0124 0.0123 0.0405
Schistosoma mansoni nuclear hormone receptor 0.0373 0.0453 0.1497
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0055 0.0033 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0077 0.0062 0.0202
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0042 0.0015 0.0038
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0327 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0005 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Entamoeba histolytica phosphomannose isomerase, putative 0.0096 0.0087 0.029
Echinococcus granulosus mothers against decapentaplegic 5 0.0065 0.0046 0.0131
Echinococcus multilocularis Polycystic kidney disease protein 0.0044 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.015 0.0158 0.0655
Schistosoma mansoni amine oxidase 0.0082 0.0069 0.0224
Echinococcus granulosus neuropeptide receptor 0.0101 0.0094 0.0267
Schistosoma mansoni hypothetical protein 0.0243 0.028 0.0926
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0791 0.1005 0.3325
Trypanosoma cruzi target of rapamycin kinase 3 0.015 0.0158 0.0554
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0025
Mycobacterium leprae Probable lipase LipE 0.0229 0.0262 0.2263
Echinococcus granulosus jumonji domain containing protein 0.004 0.0013 0.0036
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0082 0.0069 0.0797
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Brugia malayi Nuclear hormone receptor-like 1 0.0418 0.0512 0.18
Leishmania major phosphatidylinositol 3-related kinase, putative 0.015 0.0158 0.1318
Echinococcus granulosus histone acetyltransferase KAT2B 0.0053 0.0031 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Mycobacterium leprae Conserved hypothetical protein 0.0055 0.0033 0.0261
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0034 0.0005 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis D-aminoacylase, putative 0.0229 0.0262 0.0917
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Brugia malayi Latrophilin receptor protein 2 0.0243 0.028 0.0982
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0019 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Loa Loa (eye worm) hypothetical protein 0.008 0.0065 0.0267
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.005 0.0315
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0004 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0101 0.0094 0.0094
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0127 0.0128 0.1067
Onchocerca volvulus 0.0101 0.0094 0.0381
Entamoeba histolytica prolyl oligopeptidase family protein 0.0085 0.0073 0.0241
Schistosoma mansoni P2X receptor subunit 0.0207 0.0233 0.077
Echinococcus granulosus hyperpolarization activated cyclic 0.0084 0.0071 0.0202
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0034 0.0005 0.0022
Echinococcus multilocularis enteropeptidase 0.0048 0.0023 0.0023
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0152 0.0161 0.0458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0034 0.0005 0.0006
Echinococcus granulosus tachykinin peptides receptor 99D 0.0101 0.0094 0.0267
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0084 0.0071 0.0071
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0071 0.0232
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0034 0.0005 0.001
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.0406 0.0496 0.3808
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.025 0.029 0.029
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0023 0.0066
Trypanosoma cruzi GUP1, putative 0.0042 0.0015 0.0051
Brugia malayi Muscleblind-like protein 0.0146 0.0153 0.0533
Schistosoma mansoni nuclear receptor 0.0373 0.0453 0.1497
Onchocerca volvulus 0.004 0.0013 0.0043
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.015 0.0158 0.1874
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0327 0.0392 0.0392
Brugia malayi putative neuropeptide receptor NPR1 0.0101 0.0094 0.0322
Schistosoma mansoni glutaminase 0.0269 0.0316 0.1044
Echinococcus granulosus chromobox protein 1 0.0074 0.0057 0.0163
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.005
Leishmania major mitochondrial DNA polymerase beta 0.0671 0.0846 0.71
Schistosoma mansoni neuropeptide receptor 0.0101 0.0094 0.0307
Echinococcus multilocularis neuropeptides capa receptor 0.0101 0.0094 0.0094
Onchocerca volvulus 0.0101 0.0094 0.0381
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Toxoplasma gondii Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 0.0036 0.0007 0.0071
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0229 0.0262 0.1374
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0791 0.1005 0.2862
Brugia malayi AKH receptor 0.0101 0.0094 0.0322
Schistosoma mansoni histamine h1 receptor 0.0101 0.0094 0.0307
Echinococcus granulosus 7tm_1 domain containing protein 0.0101 0.0094 0.0267
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.1601
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0323 0.0387 0.1614
Loa Loa (eye worm) latrophilin receptor protein 2 0.0243 0.028 0.1167
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) trypsin family protein 0.0048 0.0023 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0791 0.1005 0.3542
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0127 0.0128 0.0834
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.0262 0.0923
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Toxoplasma gondii hypothetical protein 0.0108 0.0103 0.1224
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.0753
Brugia malayi isocitrate dehydrogenase 0.008 0.0065 0.0222
Echinococcus granulosus Protein patched homolog 1 0.0089 0.0078 0.0222
Brugia malayi prolyl oligopeptidase family protein 0.0471 0.0582 0.2047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0106 0.0373
Schistosoma mansoni hypothetical protein 0.2316 0.3021 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0031 0.009
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.0005 0.0006
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0085 0.0073 0.0247
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0013 0.003
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0229 0.0262 0.1374
Brugia malayi SWIRM domain containing protein 0.0082 0.0069 0.0233
Onchocerca volvulus 0.0327 0.0392 0.1628
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1014 0.1301 0.4588
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0791 0.1005 0.4194
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.09 0.1149 0.4798
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.045 0.0554 0.292
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0029 0.0115
Trichomonas vaginalis D-aminoacylase, putative 0.0229 0.0262 0.0917
Brugia malayi Smad1 0.0065 0.0046 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0088 0.0088
Echinococcus granulosus peregrin 0.0038 0.001 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0034 0.0005 0.001
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0034 0.0005 0.0013
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0085 0.0073 0.0253
Schistosoma mansoni biogenic amine (5HT) receptor 0.0101 0.0094 0.0307
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0659 0.0831 0.2366
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0101 0.0094 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0015 0.0042
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0406 0.0496 0.2068
Echinococcus granulosus hypothetical protein 0.0876 0.1117 0.3182
Schistosoma mansoni amine GPCR 0.0473 0.0585 0.1934
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0088 0.0308
Echinococcus multilocularis sodium and chloride dependent glycine 0.0327 0.0392 0.0392
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0084 0.0071 0.0202
Brugia malayi glutamate synthase 0.0034 0.0005 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0018 0.0018
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0373 0.0453 0.1882
Schistosoma mansoni glutamate synthase 0.0034 0.0005 0.0012
Brugia malayi Egg laying defective protein 4 0.0056 0.0034 0.0112
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0088 0.0296
Brugia malayi Trypsin family protein 0.0048 0.0023 0.0073
Onchocerca volvulus 0.1048 0.1345 0.5612
Leishmania major hypothetical protein, conserved 0.0055 0.0033 0.0267
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0029 0.0228
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0035 0.0007 0.0015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1014 0.1301 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0127 0.0128 0.1512
Brugia malayi MH2 domain containing protein 0.0065 0.0046 0.0153
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Echinococcus multilocularis p2X purinoceptor 4 0.0352 0.0426 0.0426
Brugia malayi UDP-GlcNAc:a-6-D-mannoside b1,2-N-acetylglucosaminyltransferase II 0.1765 0.2293 0.8094
Loa Loa (eye worm) hypothetical protein 0.0418 0.0512 0.2134
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0042 0.0015 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0101 0.0094 0.0267
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.041 0.0501 0.1428
Entamoeba histolytica vacuolar protein sorting 26 0.0042 0.0015 0.0038
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.015 0.0158 0.0542
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Brugia malayi intermediate filament protein 0.0112 0.0108 0.0373
Loa Loa (eye worm) transcription factor SMAD2 0.0957 0.1225 0.5114
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0092
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0932 0.1191 0.4205
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0101 0.0094 0.0267
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0317 0.0379 0.1337
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.004 0.03
Giardia lamblia GTOR 0.015 0.0158 0.0947
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0034 0.0111
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0394 0.0481 0.1369
Schistosoma mansoni RAR-like nuclear receptor 0.0791 0.1005 0.3325
Brugia malayi Bromodomain containing protein 0.0038 0.001 0.0024
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0127 0.0128 0.0421
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0088 0.0302
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Brugia malayi beta-lactamase family protein 0.0229 0.0262 0.0917
Toxoplasma gondii phosphomannose isomerase type I protein 0.0096 0.0087 0.1028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0034 0.0005 0.001
Brugia malayi Thioredoxin reductase 0.0297 0.0353 0.1238
Trichomonas vaginalis apoptosis inducing factor, putative 0.0034 0.0005 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0791 0.1005 0.2862
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0005 0.0014
Toxoplasma gondii mono- or diacylglycerol acyltransferase 0.009 0.0079 0.0933
Brugia malayi ecdysone receptor 0.0373 0.0453 0.1591
Echinococcus multilocularis Smad4 0.0065 0.0046 0.0046
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.015 0.0158 0.0554
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.2173 0.2832 1
Brugia malayi ImpB/MucB/SamB family protein 0.0106 0.0099 0.0342
Trypanosoma cruzi phosphomannose isomerase, putative 0.0096 0.0087 0.0303
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0101 0.0094 0.0267
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0024 0.0076
Trypanosoma cruzi glycerol uptake protein, putative 0.0042 0.0015 0.0051
Onchocerca volvulus 0.0112 0.0108 0.0441
Trypanosoma brucei importin beta-1 subunit, putative 0.0124 0.0123 0.0942
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0042 0.0015 0.0048
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0085 0.0073 0.0253
Echinococcus granulosus p2X purinoceptor 4 0.0352 0.0426 0.1212
Echinococcus multilocularis p2X purinoceptor 4 0.0352 0.0426 0.0426
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0791 0.1005 0.3542
Schistosoma mansoni amine GPCR 0.0101 0.0094 0.0307
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0034 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.1842 0.2394 1
Brugia malayi larval opioid receptor 0.0101 0.0094 0.0322
Echinococcus multilocularis g protein coupled receptor 0.0101 0.0094 0.0094
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0106 0.0633
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0127 0.0128 0.1512
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0096 0.0087 0.0297
Onchocerca volvulus 0.0502 0.0623 0.2594
Mycobacterium ulcerans hypothetical protein 0.0229 0.0262 0.1728
Echinococcus granulosus potassium voltage gated channel subfamily H 0.012 0.0118 0.0336
Echinococcus multilocularis sterol O acyltransferase 1 0.0042 0.0015 0.0015
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1628 0.2111 0.7453
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Loa Loa (eye worm) hypothetical protein 0.0791 0.1005 0.4194
Onchocerca volvulus 0.0229 0.0262 0.1085
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0034 0.0005 0.0013
Brugia malayi MBOAT family protein 0.0042 0.0015 0.0045
Mycobacterium ulcerans hypothetical protein 0.0034 0.0005 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0101 0.0771
Loa Loa (eye worm) hypothetical protein 0.0078 0.0063 0.0257
Toxoplasma gondii NADPH-glutathione reductase 0.0127 0.0128 0.1527
Loa Loa (eye worm) bromodomain containing protein 0.004 0.0013 0.0048
Mycobacterium ulcerans hypothetical protein 0.0055 0.0033 0.0199
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0015 0.0059
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0004 0.0011
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0329 0.0394 0.1302
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi MH1 domain containing protein 0.0036 0.0008 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.0373 0.0453 0.1497
Onchocerca volvulus Matrilysin homolog 0.1639 0.2126 0.8879
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1818 0.2362 0.8338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Echinococcus granulosus o acyltransferase membrane bound domain 0.0042 0.0015 0.0044
Schistosoma mansoni hypothetical protein 0.0042 0.0015 0.0047
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.1067
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0046 0.0537
Echinococcus multilocularis transmembrane protease serine 3 0.0048 0.0023 0.0023
Echinococcus granulosus 7TM GPCR rhodopsin 0.0101 0.0094 0.0267
Loa Loa (eye worm) prolyl oligopeptidase 0.085 0.1084 0.4524
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Mycobacterium ulcerans hypothetical protein 0.0048 0.0023 0.0137
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0013 0.0043
Brugia malayi MH1 domain containing protein 0.0065 0.0046 0.0153
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0101 0.0094 0.0094
Echinococcus granulosus p2X purinoceptor 4 0.0352 0.0426 0.1212
Entamoeba histolytica prolyl oligopeptidase family protein 0.0085 0.0073 0.0241
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0055 0.0033 0.0033
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0671 0.0846 0.6503
Mycobacterium tuberculosis Conserved protein 0.0229 0.0262 0.1374
Brugia malayi Trypsin family protein 0.0048 0.0023 0.0073
Mycobacterium ulcerans beta-lactamase 0.0229 0.0262 0.1728
Onchocerca volvulus 0.0373 0.0453 0.1882
Schistosoma mansoni 60S ribosomal protein L21 0.0065 0.0045 0.0147
Schistosoma mansoni hypothetical protein 0.0086 0.0074 0.0241
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.2173 0.2832 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0003 0.0006
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1628 0.2111 0.7453
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0042 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0054 0.0031 0.0127
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.2023 0.2634 0.93
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0101 0.0094 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0065 0.0212
Echinococcus granulosus sodium and chloride dependent glycine 0.0327 0.0392 0.1117
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.008 0.0065 0.0228
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0791 0.1005 0.4194
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Schistosoma mansoni ran 0.0068 0.005 0.0161
Plasmodium vivax hypothetical protein 0.015 0.0158 0.1874
Treponema pallidum cyclic nucleotide binding protein 0.0055 0.0033 0.0118
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0084 0.0072 0.0364
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0034 0.0005 0.0039
Loa Loa (eye worm) hypothetical protein 0.156 0.2021 0.8442
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Leishmania major glycerol uptake protein, putative 0.0042 0.0015 0.0122
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.0005 0.0006
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis cpg binding protein 0.0103 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Mycobacterium tuberculosis Probable dehydrogenase 0.045 0.0554 0.292
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0739 0.0936 0.3098
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0042 0.0015 0.0044
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0044 0.0018 0.0047
Brugia malayi Probable ClpP-like protease 0.008 0.0065 0.022
Brugia malayi G-protein coupled receptor 0.0101 0.0094 0.0322
Loa Loa (eye worm) hypothetical protein 0.0055 0.0033 0.0131
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0055 0.0033 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0791 0.1005 0.3325
Onchocerca volvulus Matrix metalloproteinase homolog 0.1639 0.2126 0.8879
Trypanosoma cruzi prolyl endopeptidase 0.0085 0.0073 0.0253
Brugia malayi hypothetical protein 0.0044 0.0018 0.0056
Loa Loa (eye worm) hypothetical protein 0.0085 0.0072 0.0295
Mycobacterium leprae Possible transporter protein 0.0035 0.0007 0.0036
Schistosoma mansoni intermediate filament proteins 0.0112 0.0108 0.0355
Trypanosoma cruzi DNA polymerase eta, putative 0.0052 0.0029 0.01
Plasmodium falciparum protoporphyrinogen oxidase 0.0082 0.0069 0.0797
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0436 0.0536 0.2824
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0005 0.001
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0011 0.003
Schistosoma mansoni amine GPCR 0.0101 0.0094 0.0307
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0085 0.0073 0.0241
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0019 0.0051
Loa Loa (eye worm) MBOAT family protein 0.0042 0.0015 0.0059
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.0554
Mycobacterium ulcerans esterase/lipase LipP 0.0229 0.0262 0.1728
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0035 0.0007 0.0015
Brugia malayi Nuclear hormone receptor E75 0.0373 0.0453 0.1591
Echinococcus granulosus biogenic amine 5HT receptor 0.0101 0.0094 0.0267
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0101 0.0094 0.0094
Loa Loa (eye worm) acetyltransferase 0.017 0.0185 0.0769
Brugia malayi CXXC zinc finger family protein 0.0093 0.0083 0.0285
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0892 0.1139 0.4012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0052 0.0391
Echinococcus granulosus voltage gated potassium channel 0.012 0.0118 0.0336
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0071 0.0241
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0188 0.0208 0.0594
Schistosoma mansoni hypothetical protein 0.0056 0.0034 0.011
Brugia malayi hypothetical protein 0.0101 0.0094 0.0322
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0127 0.0128 0.0249
Trypanosoma brucei DNA polymerase eta, putative 0.0106 0.0099 0.0758
Onchocerca volvulus 0.0101 0.0094 0.0381
Echinococcus multilocularis glutamate synthase 0.0034 0.0005 0.0005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0106 0.0886
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0317 0.0379 0.2912
Onchocerca volvulus 0.0101 0.0094 0.0381
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Echinococcus granulosus GTP binding nuclear protein Ran 0.0068 0.005 0.0141
Schistosoma mansoni chromobox protein 0.0074 0.0057 0.0187
Onchocerca volvulus 0.0101 0.0094 0.0381
Loa Loa (eye worm) hypothetical protein 0.0327 0.0392 0.1634
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0034 0.0005 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0101 0.0094 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0013 0.0037
Brugia malayi amine oxidase, flavin-containing family protein 0.0082 0.0069 0.0233
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0048 0.0162
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0373 0.0453 0.129
Onchocerca volvulus 0.0327 0.0392 0.1628
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0127 0.0128 0.1512
Schistosoma mansoni thyroid hormone receptor 0.0791 0.1005 0.3325
Echinococcus granulosus fetal alzheimer antigen falz 0.0051 0.0027 0.0078
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.015 0.0158 0.1207
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.085 0.1084 0.1084
Schistosoma mansoni voltage-gated potassium channel 0.012 0.0118 0.0387
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0106 0.0106
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0065 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0105 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0329 0.0394 0.1642
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.005 0.0142
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0035 0.0007 0.0015
Echinococcus granulosus chromobox protein 1 0.0074 0.0057 0.0163
Echinococcus multilocularis alpha 1,3 mannosyl glycoprotein 0.0105 0.0099 0.0099
Leishmania major hypothetical protein, conserved 0.0055 0.0033 0.0267
Echinococcus multilocularis zinc finger protein 0.0049 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0059
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0055 0.0033 0.0033
Trichomonas vaginalis adenylate cyclase type, putative 0.0035 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0105 0.0099 0.041
Echinococcus granulosus alpha 13 mannosyl glycoprotein 0.0105 0.0099 0.0282
Brugia malayi Trypsin family protein 0.0048 0.0023 0.0073
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0327 0.0392 0.4712
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0013 0.003
Onchocerca volvulus 0.0034 0.0005 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0101 0.0094 0.0094
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0791 0.1005 0.1005
Loa Loa (eye worm) hypothetical protein 0.015 0.0158 0.0655
Leishmania major diacylglycerol acyltransferase, putative 0.009 0.0079 0.0653
Loa Loa (eye worm) hypothetical protein 0.0276 0.0325 0.1354
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0042 0.0015 0.0015
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.0107 0.0101 0.0771
Trypanosoma brucei protein kinase A regulatory subunit 0.0055 0.0033 0.0244
Loa Loa (eye worm) hypothetical protein 0.0373 0.0453 0.1887
Schistosoma mansoni hypothetical protein 0.0524 0.0652 0.2158
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0791 0.1005 0.1005
Mycobacterium ulcerans DNA polymerase IV 0.0107 0.0101 0.0656
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0088 0.0076 0.0903
Trypanosoma brucei trypanothione reductase 0.0297 0.0353 0.2709
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0031 0.0231
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0791 0.1005 0.2862
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0101 0.0094 0.0322
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0072 0.0234
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0406 0.0496 0.1748
Loa Loa (eye worm) hypothetical protein 0.0208 0.0234 0.0975
Echinococcus granulosus GPCR family 2 0.0243 0.028 0.0799
Leishmania major protein kinase, putative 0.0056 0.0034 0.0281
Schistosoma mansoni microtubule-associated protein tau 0.1463 0.1893 0.6265
Giardia lamblia Glutamate synthase 0.0034 0.0005 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0101 0.0094 0.0094
Schistosoma mansoni pyruvate kinase 0.0032 0.0003 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0215 0.0244 0.0853
Echinococcus multilocularis Zinc finger, PHD finger 0.0659 0.0831 0.0831
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0124 0.0408
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0418 0.0512 0.0512
Brugia malayi glutaminase DH11.1 0.0269 0.0316 0.1108
Schistosoma mansoni diacylglycerol O-acyltransferase 0.009 0.0079 0.0258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0005 0.001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0101 0.0094 0.0267
Toxoplasma gondii hypothetical protein 0.0327 0.0392 0.4712
Brugia malayi PHD-finger family protein 0.006 0.0039 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Loa Loa (eye worm) matrixin family protein 0.1787 0.2321 0.9696
Schistosoma mansoni ran 0.0068 0.005 0.0161
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.004 0.0013 0.0043
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Giardia lamblia Hypothetical protein 0.015 0.0158 0.0947
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0077 0.0062 0.0253
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0044 0.0152
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0046 0.0046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0353 0.0427 0.2246
Schistosoma mansoni lamin 0.0112 0.0108 0.0355
Brugia malayi neuropeptide F receptor 0.0101 0.0094 0.0322
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0791 0.1005 0.1005
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0072 0.0072
Trypanosoma cruzi phosphomannose isomerase, putative 0.0096 0.0087 0.0303
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0055 0.0033 0.0093
Echinococcus granulosus neuropeptides capa receptor 0.0101 0.0094 0.0267
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0329 0.0394 0.1123
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0023 0.0074
Echinococcus granulosus tm gpcr rhodopsin 0.0101 0.0094 0.0267
Plasmodium vivax hypothetical protein, conserved 0.015 0.0158 0.1874
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0127 0.0128 0.0977
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0034 0.0005 0.001
Onchocerca volvulus 0.0327 0.0392 0.1628
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1842 0.2394 0.7925
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0034 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0101 0.0094 0.0387
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0152 0.0161 0.0161
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.015 0.0158 0.0542
Loa Loa (eye worm) glutaminase 0.0269 0.0316 0.1316
Echinococcus granulosus serotonin receptor 0.0101 0.0094 0.0267
Brugia malayi Heterochromatin protein 1 0.0074 0.0057 0.0193
Echinococcus multilocularis dna polymerase eta 0.0106 0.0099 0.0099
Toxoplasma gondii isocitrate dehydrogenase 0.008 0.0065 0.0773
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.1091
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0035 0.0007 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0101 0.0094 0.0307
Schistosoma mansoni jumonji/arid domain-containing protein 0.0102 0.0095 0.0311
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0406 0.0496 0.1748
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0013 0.0037
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.045 0.0554 0.4808
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.015 0.0158 0.0548
Loa Loa (eye worm) beta-lactamase 0.0229 0.0262 0.1091
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0023 0.0136
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0418 0.0512 0.1692
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0106 0.0373
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0127 0.0128 0.0449
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0101 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0007 0.0015
Loa Loa (eye worm) nuclear hormone receptor 0.0373 0.0453 0.1887
Trypanosoma cruzi glycerol uptake protein, putative 0.0042 0.0015 0.0051
Leishmania major C-8 sterol isomerase-like protein 0.0773 0.0982 0.8239
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0034 0.0005 0.0014
Leishmania major protein kinase, putative 0.0056 0.0034 0.0281
Mycobacterium leprae PROBABLE HYDROLASE 0.09 0.1149 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0007
Mycobacterium tuberculosis Conserved protein 0.0229 0.0262 0.1374
Entamoeba histolytica hypothetical protein 0.0188 0.0208 0.0721
Brugia malayi Matrixin family protein 0.0739 0.0936 0.3301
Loa Loa (eye worm) hypothetical protein 0.0048 0.0023 0.0093
Leishmania major hypothetical protein, unknown function 0.015 0.0158 0.1318
Onchocerca volvulus 0.0048 0.0023 0.0086
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0791 0.1005 0.3542
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0053 0.0031 0.0099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0107 0.0101 0.0354
Loa Loa (eye worm) hhat protein 0.0042 0.0015 0.0059
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0013 0.0037
Leishmania major glycerol uptake protein, putative 0.0042 0.0015 0.0122
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0932 0.1191 0.3394
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0011 0.0076
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0373 0.0453 0.1497
Schistosoma mansoni inositol monophosphatase 0.0038 0.0011 0.0033
Plasmodium falciparum glutathione reductase 0.0127 0.0128 0.1512
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.025 0.029 0.3469
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0101 0.0094 0.0267
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.015 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0243 0.028 0.1167
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0007 0.0015
Schistosoma mansoni cpg binding protein 0.0093 0.0083 0.0273
Mycobacterium ulcerans dehydrogenase 0.0082 0.0069 0.0439
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0007 0.0015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0056 0.0056
Brugia malayi MBOAT family protein 0.0042 0.0015 0.0045
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0003 0.0014
Brugia malayi Matrixin family protein 0.1787 0.2321 0.8195
Brugia malayi Pre-SET motif family protein 0.0441 0.0543 0.1908
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0088 0.0364
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0069 0.0197
Loa Loa (eye worm) hypothetical protein 0.0082 0.0069 0.0282
Echinococcus multilocularis musashi 0.0112 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.0014
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0932 0.1191 0.3942
Mycobacterium tuberculosis Probable esterase LipL 0.0229 0.0262 0.1374
Schistosoma mansoni neuropeptide receptor 0.0101 0.0094 0.0307
Loa Loa (eye worm) hypothetical protein 0.0273 0.0321 0.1335
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.015 0.0158 0.0542
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Brugia malayi photoreceptor-specific nuclear receptor 0.0791 0.1005 0.3542
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0229 0.0262 0.0917
Schistosoma mansoni hypothetical protein 0.0044 0.0018 0.0058
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0019 0.0067
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0106 0.0886
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0088 0.0733
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0085 0.0295
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0101 0.0094 0.0307
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0068 0.005 0.0375
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0158 0.0548
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.009 0.0079 0.0275
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0892 0.1139 0.4016
Echinococcus granulosus dnaJ subfamily B 0.133 0.1718 0.4893
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0004 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0101 0.0094 0.0267
Echinococcus granulosus beta LACTamase domain containing family member 0.0229 0.0262 0.0747
Trichomonas vaginalis adenylate cyclase type III, putative 0.0035 0.0007 0.0015
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.015 0.0158 0.1207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0791 0.1005 0.4194
Echinococcus granulosus serine protein kinase ATM 0.015 0.0158 0.045
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0327 0.0392 0.1295
Trypanosoma brucei C-8 sterol isomerase, putative 0.0773 0.0982 0.7546
Loa Loa (eye worm) hypothetical protein 0.0112 0.0108 0.0447
Entamoeba histolytica hypothetical protein 0.015 0.0158 0.0542
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.015 0.0158 0.045
Leishmania major NADH dehydrogenase, putative 0.0034 0.0005 0.003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.015 0.0158 0.1207
Trichomonas vaginalis Importin beta-1 subunit, putative 0.01 0.0092 0.0317
Loa Loa (eye worm) hypothetical protein 0.1054 0.1352 0.5646
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0007 0.0015

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 50 % Activity of recombinant BACE assessed as substrate cleavage at 300 uM after 3 hrs by HPLC analysis ChEMBL. 21489805
Time (binding) = 30.11 min Activity of recombinant BACE assessed as time required for substrate cleavage reaction by HPLC method ChEMBL. 21489805

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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