Detailed information for compound 1184822

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 370.405 | Formula: C21H22FNO4
  • H donors: 0 H acceptors: 1 LogP: 3.47 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: [18F]CCOCCOc1ccc2c(c1)c(=O)cc(o2)c1ccc(cc1)N(C)C
  • InChi: 1S/C21H22FNO4/c1-23(2)16-5-3-15(4-6-16)21-14-19(24)18-13-17(7-8-20(18)27-21)26-12-11-25-10-9-22/h3-8,13-14H,9-12H2,1-2H3/i22-1
  • InChiKey: XRLQFRHTRFJILQ-KVTPGWOSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0031 0.0071 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.3721
Brugia malayi eukaryotic initiation factor 4A 0.025 0.1043 0.1043
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0184 0.0184
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.0752 0.153
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0424 0.181 0.3083
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0031 0.0071 0.0082
Entamoeba histolytica hypothetical protein 0.0049 0.0151 0.021
Trichomonas vaginalis AGC family protein kinase 0.0162 0.065 0.1073
Entamoeba histolytica p21-activated kinase 0.0035 0.0089 0.0102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0142 0.0142
Echinococcus multilocularis survival motor neuron protein 1 0.0727 0.3151 0.38
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0012 0.001
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0035 0.0089 0.0102
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0012 0.001
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.003 0.003
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0249 0.126
Loa Loa (eye worm) PH domain-containing protein 0.0031 0.0071 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0216 0.0889 0.1069
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0151 0.0151
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0034 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1302 0.2203
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Echinococcus multilocularis Ras associated and pleckstrin y 0.0031 0.0071 0.0082
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0313 0.1319 1
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0049 0.0151 0.1117
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0034 0.0037
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.047 0.2017 0.2017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0142 0.0167
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.047 0.2314
Brugia malayi beta-lactamase family protein 0.0071 0.0249 0.0249
Mycobacterium tuberculosis Conserved protein 0.0071 0.0249 0.126
Schistosoma mansoni cellular tumor antigen P53 0.0041 0.0117 0.0138
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0031 0.0071 0.0072
Entamoeba histolytica hypothetical protein, conserved 0.0031 0.0071 0.0072
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0151 0.0179
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0185 0.0753 0.0905
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0029 0.0029
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0162 0.065 0.065
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0162 0.065 0.078
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0209 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Echinococcus granulosus geminin 0.0348 0.1474 0.1775
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0031 0.0071 0.0072
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0035 0.0089 0.0085
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.0249
Schistosoma mansoni centaurin alpha 0.0031 0.0071 0.0082
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0002
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0306 0.1554
Echinococcus granulosus survival motor neuron protein 1 0.0727 0.3151 0.38
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0001
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1887 0.8287 1
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.021 0.0249
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Toxoplasma gondii phosphatidylinositol transfer protein 0.0031 0.0071 0.0331
Toxoplasma gondii AGC kinase 0.047 0.2017 1
Schistosoma mansoni syntrophin 0.0031 0.0071 0.0082
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.0753
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0209 0.0248
Loa Loa (eye worm) hypothetical protein 0.109 0.4758 0.4758
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0027 0.0055 0.0051
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0071 0.0507
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Plasmodium vivax ataxin-2 like protein, putative 0.0046 0.014 0.1031
Leishmania major hypothetical protein, conserved 0.0031 0.0071 0.0067
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0027 0.0055 0.0257
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.021 0.0249
Echinococcus granulosus oxysterol binding protein 3 0.0031 0.0071 0.0082
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.025 0.1043 0.1755
Leishmania major hypothetical protein, conserved 0.0046 0.014 0.0136
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0031 0.0071 0.0082
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0031 0.0071 0.0082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0209 0.1015
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0031 0.0071 0.0082
Mycobacterium ulcerans hypothetical protein 0.0071 0.0249 1
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0216 0.0889 0.0889
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0424 0.181 0.3083
Entamoeba histolytica PH domain containing protein kinase, putative 0.0035 0.0089 0.0102
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Schistosoma mansoni hypothetical protein 0.0081 0.0293 0.035
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Echinococcus multilocularis oxysterol binding protein 3 0.0031 0.0071 0.0082
Entamoeba histolytica PH domain containing protein 0.0031 0.0071 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.0072
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0027 0.0055 0.0051
Trypanosoma brucei rac serine-threonine kinase, putative 0.0501 0.2153 0.2153
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.003 0.003
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0889 0.0886
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0029 0.0031
Brugia malayi isocitrate dehydrogenase 0.0016 0.0005 0.0005
Entamoeba histolytica PH domain containing protein 0.0031 0.0071 0.0072
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0216 0.0889 0.4396
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.025 0.1043 0.104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0122 0.0118
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1643 0.7209 0.8699
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0122 0.0585
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0027 0.0055 0.0257
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.0753
Toxoplasma gondii AtPH1 family protein 0.0031 0.0071 0.0331
Echinococcus granulosus DCC interacting protein 13 beta 0.0031 0.0071 0.0082
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.003 0.0032
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0049 0.0151 0.0179
Onchocerca volvulus 0.0031 0.0071 0.009
Loa Loa (eye worm) hypothetical protein 0.0185 0.0752 0.0752
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0142 0.0167
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0306 0.1554
Trichomonas vaginalis esterase, putative 0.0071 0.0249 0.0379
Brugia malayi hypothetical protein 0.0073 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0055
Onchocerca volvulus 0.0063 0.0212 0.0386
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0031 0.0071 0.0082
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0005 0.0001
Echinococcus multilocularis beta 1 syntrophin 0.0031 0.0071 0.0082
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0049 0.0151 0.0179
Brugia malayi Variant SH3 domain containing protein 0.0031 0.0071 0.0071
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.025 0.1043 0.1256
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Echinococcus granulosus GPCR family 2 0.0081 0.0293 0.035
Loa Loa (eye worm) syntrophin-1 0.0031 0.0071 0.0071
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Entamoeba histolytica hypothetical protein 0.0073 0.0257 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0122 0.0118
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0034 0.0034
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0185 0.0753 0.0905
Echinococcus granulosus oxysterol binding protein 1 0.0031 0.0071 0.0082
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0097 0.0094
Plasmodium falciparum calcium-dependent protein kinase 7 0.0035 0.0089 0.0642
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0029 0.0029
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0249 0.126
Brugia malayi ecdysteroid receptor 0.0021 0.0029 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0029 0.0029
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0306 0.8585
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0309 0.1302 0.1302
Schistosoma mansoni dynamin 0.0031 0.0071 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.003 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0029 0.0031
Echinococcus multilocularis nervana 2 0.0309 0.1302 0.1567
Schistosoma mansoni oxysterol-binding protein 1 0.0031 0.0071 0.0082
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0049 0.0151 0.0151
Echinococcus multilocularis cpg binding protein 0.0068 0.0236 0.0281
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.0148
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0057
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0151 0.021
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0293 0.0293
Brugia malayi Variant SH3 domain containing protein 0.0031 0.0071 0.0071
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0216 0.0889 0.1069
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0049 0.0151 0.0179
Treponema pallidum ATP-dependent RNA helicase 0.025 0.1043 0.2008
Entamoeba histolytica hypothetical protein 0.0049 0.0151 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Leishmania major phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.0148
Echinococcus granulosus Pleckstrin y 0.0031 0.0071 0.0082
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0249 0.0297
Schistosoma mansoni survival motor neuron protein 0.0148 0.0591 0.0709
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0027 0.0055 0.0257
Echinococcus multilocularis cytohesin 1 0.0031 0.0071 0.0082
Giardia lamblia Hypothetical protein 0.0049 0.0151 0.0353
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0005 0.0004
Echinococcus multilocularis sodium and chloride dependent glycine 0.0185 0.0753 0.0905
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0027 0.0055 0.112
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0162 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.0249
Brugia malayi beta-lactamase family protein 0.0071 0.0249 0.0249
Trichomonas vaginalis centaurin gamma, putative 0.0031 0.0071 0.0072
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0249 0.0297
Entamoeba histolytica hypothetical protein 0.0073 0.0257 0.0394
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0029 0.0031
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0031 0.0071 0.0082
Schistosoma mansoni atypical protein kinase C 0.0162 0.065 0.078
Trichomonas vaginalis kinesin light chain, putative 0.0031 0.0071 0.0072
Entamoeba histolytica PH domain containing protein kinase, putative 0.0035 0.0089 0.0102
Schistosoma mansoni lipoxygenase 0.0022 0.0034 0.0037
Brugia malayi Protein kinase domain containing protein 0.0162 0.065 0.065
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0001
Echinococcus granulosus cpg binding protein 0.0068 0.0236 0.0281
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Mycobacterium tuberculosis Probable reductase 0.0084 0.0306 0.1554
Loa Loa (eye worm) pax transcription factor protein 2 0.0248 0.1035 0.1035
Schistosoma mansoni coup transcription factor 0.0021 0.0029 0.0031
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0209 0.0205
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0216 0.0889 0.4396
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Echinococcus granulosus serotonin transporter 0.109 0.4758 0.574
Brugia malayi steroid hormone receptor 0.0021 0.0029 0.0029
Loa Loa (eye worm) phosphatidylinositol 3 0.0375 0.1593 0.1593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trypanosoma brucei protein kinase, putative 0.0035 0.0089 0.0089
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0034 0.0037
Trypanosoma brucei PAB1-binding protein , putative 0.0046 0.014 0.014
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0249 0.0379
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0049 0.0151 0.0179
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0049 0.0151 0.021
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0309 0.1302 0.1567
Brugia malayi Calcitonin receptor-like protein seb-1 0.0256 0.1069 0.1069
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Trichomonas vaginalis hypothetical protein 0.0031 0.0071 0.0072
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0057 0.0057
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.011 0.0802
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.004 0.011 0.0139
Brugia malayi cytochrome P450 0.0027 0.0055 0.0055
Onchocerca volvulus 0.0248 0.1035 0.2126
Brugia malayi p70 ribosomal S6 kinase beta 0.047 0.2017 0.2017
Echinococcus granulosus Glutaredoxin protein 5 0.0309 0.1304 0.157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) AGC/NDR protein kinase 0.0162 0.065 0.065
Leishmania major protein kinase, putative 0.0035 0.0089 0.0085
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.0072
Brugia malayi probable spectrin beta chain 0.0031 0.0071 0.0071
Echinococcus granulosus NDR protein kinase 0.0162 0.065 0.078
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0031 0.0071 0.0067
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.021 0.8214
Schistosoma mansoni serine/threonine-protein kinase 0.0344 0.1456 0.1754
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0097 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0029 0.0029
Toxoplasma gondii hypothetical protein 0.0031 0.0071 0.0331
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0142 0.0167
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0028 0.0028
Brugia malayi MAP kinase sur-1 0.0062 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Echinococcus multilocularis protein kinase c epsilon type 0.0162 0.065 0.078
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0184 0.0184
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0029 0.0029
Leishmania major folate/biopterin transporter, putative 0.0035 0.0089 0.0085
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.0148
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.0249
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0313 0.1319 0.1589
Toxoplasma gondii Oxysterol-binding protein 0.0031 0.0071 0.0331
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0031 0.0071 0.0082
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.021 0.0206
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0522 0.0626
Loa Loa (eye worm) hypothetical protein 0.0743 0.3222 0.3222
Toxoplasma gondii FATC domain-containing protein 0.0049 0.0151 0.073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Toxoplasma gondii protein kinase domain-containing protein 0.0035 0.0089 0.042
Echinococcus granulosus nervana 2 0.0309 0.1302 0.1567
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0027 0.0055 0.112
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1326 0.5804 0.5803
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0027 0.0055 0.112
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0031 0.0071 0.0072
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0031 0.0071 0.0067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0029 0.0031
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0513 0.0513
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.025 0.1043 0.1755
Loa Loa (eye worm) hypothetical protein 0.109 0.4758 0.4758
Brugia malayi Steroid receptor seven-up type 2 0.0111 0.0428 0.0428
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0142 0.0167
Brugia malayi hypothetical protein 0.0022 0.0034 0.0034
Onchocerca volvulus 0.0185 0.0753 0.1532
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0049 0.0151 0.073
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0027 0.0055 0.112
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0049 0.0151 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0031 0.0071 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0122 0.016
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0031 0.0071 0.0507
Brugia malayi hypothetical protein 0.0181 0.0736 0.0736
Brugia malayi TBC domain containing protein 0.0031 0.0071 0.0071
Echinococcus multilocularis serine:threonine protein kinase N2 0.0162 0.065 0.078
Schistosoma mansoni hypothetical protein 0.0148 0.0591 0.0709
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.011 0.011
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0034 0.0037
Echinococcus granulosus protein kinase C gamma type 0.0162 0.065 0.078
Echinococcus multilocularis pdz domain containing protein 0.0031 0.0071 0.0082
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0029 0.0029
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0027 0.0055 0.112
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0257 0.1072 0.303
Entamoeba histolytica protein kinase, putative 0.0035 0.0089 0.0102
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0049 0.0151 0.021
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0209 0.0248
Trypanosoma cruzi PH domain containing protein, putative 0.0031 0.0071 0.0067
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0249 0.0249
Brugia malayi Dynamin 0.0031 0.0071 0.0071
Echinococcus granulosus Oxysterol binding protein 11 0.0031 0.0071 0.0082
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0049 0.0151 0.0151
Trichomonas vaginalis protein transport protein sec7, putative 0.0031 0.0071 0.0072
Echinococcus granulosus pleckstrin y domain containing family A 0.0031 0.0071 0.0082
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0049 0.0151 0.0179
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0209 0.0209
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.003 0.0026
Leishmania major cytochrome p450-like protein 0.0056 0.0184 0.018
Brugia malayi Cytochrome P450 family protein 0.0027 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0891 0.3881 0.4681
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0027 0.0055 0.0257
Echinococcus granulosus myotubularin protein 13 0.0031 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0035 0.0089 0.0085
Toxoplasma gondii cytochrome p450 superfamily protein 0.0027 0.0055 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0031 0.0071 0.0082
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0049 0.0151 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Echinococcus multilocularis DCC interacting protein 13 beta 0.0031 0.0071 0.0082
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0293 0.0293
Brugia malayi Thioredoxin reductase 0.0037 0.0097 0.0097
Trichomonas vaginalis protein transport protein sec7, putative 0.0031 0.0071 0.0072
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0375 0.1593 0.159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.025 0.1043 0.2145
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0027 0.0055 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1118 0.4883 0.8405
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.021 0.0249
Echinococcus granulosus eukaryotic initiation factor 4A 0.025 0.1043 0.1256
Mycobacterium ulcerans beta-lactamase 0.0071 0.0249 1
Schistosoma mansoni rab6-interacting 0.0022 0.0034 0.0037
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0216 0.0889 0.1488
Onchocerca volvulus 0.0049 0.0151 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Entamoeba histolytica hypothetical protein 0.0035 0.0089 0.0102
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0424 0.181 0.181
Loa Loa (eye worm) hypothetical protein 0.0029 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0049 0.0151 0.021
Schistosoma mansoni hypothetical protein 0.0081 0.0293 0.035
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0151 0.021
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0209 0.031
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0027 0.0055 0.112
Loa Loa (eye worm) phosphatidylinositol kinase 0.0049 0.0151 0.0151
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0057 0.0057
Entamoeba histolytica PH domain containing protein kinase, putative 0.0344 0.1456 0.247
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Onchocerca volvulus 0.0071 0.0249 0.0465
Onchocerca volvulus 0.109 0.4758 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0313 0.1319 0.1316
Trypanosoma cruzi NIMA-related kinase, putative 0.0035 0.0089 0.0085
Leishmania major protein kinase, putative 0.0022 0.0032 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0055 0.0051
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.0122 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0029 0.0029
Echinococcus multilocularis calcium dependent secretion activator 1 0.0031 0.0071 0.0082
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0029 0.0031
Plasmodium falciparum oxysterol-binding protein, putative 0.0031 0.0071 0.0507
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0249 0.0297
Onchocerca volvulus 0.0049 0.0151 0.0259
Schistosoma mansoni hypothetical protein 0.0348 0.1474 0.1775
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.011 0.0106
Echinococcus multilocularis lamin dm0 0.0028 0.0057 0.0065
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Plasmodium vivax hypothetical protein 0.0049 0.0151 0.1117
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.1117
Loa Loa (eye worm) inositol-1 0.0042 0.0122 0.0122
Brugia malayi hypothetical protein 0.003 0.0067 0.0067
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0209 0.052
Schistosoma mansoni zinc finger protein 0.0031 0.0071 0.0082
Brugia malayi Hr1 repeat family protein 0.0162 0.065 0.065
Loa Loa (eye worm) histone methyltransferase 0.0019 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0256 0.1069 0.1069
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0249 0.126
Toxoplasma gondii ABC1 family protein 0.0071 0.0249 0.1215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0029 0.0029
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0031 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.025 0.1043 0.5163
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.011 0.0129
Echinococcus multilocularis Zinc finger, PHD finger 0.0216 0.0889 0.1069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Brugia malayi nuclear receptor NHR-88 0.0021 0.0029 0.0029
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0049 0.0151 0.0151
Loa Loa (eye worm) phosphatidylinositol 3 0.1679 0.7366 0.7366
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.0753
Schistosoma mansoni ap endonuclease 0.004 0.011 0.0129
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0035 0.0089 0.0089
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0031 0.0071 0.0082
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.011 0.0106
Onchocerca volvulus Glucosylceramidase homolog 0.0203 0.0832 0.1698
Echinococcus multilocularis sodium and chloride dependent glycine 0.0185 0.0753 0.0905
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0031 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Brugia malayi CXXC zinc finger family protein 0.0063 0.0212 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0209 0.031
Onchocerca volvulus 0.0031 0.0071 0.009
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0029 0.0029
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0049 0.0151 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0216 0.0889 0.0889
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0103 0.0505
Plasmodium falciparum transporter, putative 0.0185 0.0753 0.5695
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0049 0.0151 0.0148
Mycobacterium leprae Probable lipase LipE 0.0071 0.0249 0.6637
Onchocerca volvulus 0.0022 0.0034 0.001
Trypanosoma brucei ISWI complex protein 0.0016 0.0004 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.109 0.4758 0.4758
Echinococcus granulosus eukaryotic initiation factor 4A III 0.025 0.1043 0.1256
Echinococcus multilocularis rac serine:threonine kinase 0.0344 0.1456 0.1754
Toxoplasma gondii hypothetical protein 0.0185 0.0753 0.3721
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0035 0.0089 0.0085
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0031 0.0071 0.0071
Entamoeba histolytica protein kinase, putative 0.0035 0.0089 0.0102
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0027 0.0055 0.112
Toxoplasma gondii thioredoxin reductase 0.0037 0.0097 0.0461
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0029 0.0031
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0162 0.065 0.078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0014 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0034 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Echinococcus multilocularis GPCR, family 2 0.0081 0.0293 0.035
Loa Loa (eye worm) hypothetical protein 0.0583 0.2516 0.2516
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.003 0.0026
Echinococcus multilocularis 0.0049 0.0151 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0185 0.0753 0.0753
Echinococcus multilocularis musashi 0.0028 0.0057 0.0065
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0029 0.0029
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0049 0.0151 0.021
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0035 0.0089 0.042
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0031 0.0071 0.0071
Onchocerca volvulus 0.0028 0.0057 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0031 0.0071 0.009
Trypanosoma cruzi PH domain containing protein, putative 0.0031 0.0071 0.0067
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0151 0.0148
Schistosoma mansoni hypothetical protein 0.0027 0.0055 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0031 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0727 0.3151 0.3151
Schistosoma mansoni goodpasture antigen-binding protein 0.0031 0.0071 0.0082
Echinococcus multilocularis Oxysterol binding protein 11 0.0031 0.0071 0.0082
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0221 0.0263
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0158 0.0632 0.1042
Echinococcus multilocularis lamin 0.0028 0.0057 0.0065
Onchocerca volvulus Protein melted homolog 0.0031 0.0071 0.009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0249 0.0249
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0034 0.0037
Echinococcus multilocularis zinc finger protein 0.0024 0.0039 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0029 0.0029
Schistosoma mansoni cpg binding protein 0.0068 0.0236 0.0281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0018 0.0018
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0216 0.0889 0.1069
Brugia malayi Doublecortin family protein 0.0022 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0049 0.0151 0.073
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Schistosoma mansoni serine/threonine-protein kinase 0.0344 0.1458 0.1756
Onchocerca volvulus 0.0022 0.0034 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Onchocerca volvulus 0.0041 0.0117 0.0187
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0029 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Schistosoma mansoni bromodomain containing protein 0.0068 0.0237 0.0282
Echinococcus multilocularis vesicular acetylcholine transporter 0.0877 0.3817 0.4603
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.025 0.1043 0.1043
Brugia malayi Plekhf2 protein 0.0031 0.0071 0.0071
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0216 0.0889 0.1488
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0029 0.0031
Entamoeba histolytica PH domain containing protein kinase, putative 0.0344 0.1456 0.247
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0151 0.0148
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0035 0.0089 0.0102
Toxoplasma gondii LsmAD domain-containing protein 0.0046 0.014 0.0673
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0306 0.1554
Loa Loa (eye worm) glutathione reductase 0.0037 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Schistosoma mansoni hypothetical protein 0.0031 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Onchocerca volvulus 0.0031 0.0071 0.009
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0031 0.0071 0.0071
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.01 0.0116
Echinococcus granulosus Rho GTPase activating protein 24 0.0031 0.0071 0.0082
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.025 0.1043 0.1755
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1326 0.5804 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0014 0.001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0185 0.0753 0.0905
Leishmania major serine/threonine-protein kinase a, putative 0.0035 0.0089 0.0085
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0889 0.0886
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0256 0.1069 0.1069
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0049 0.0151 0.0179
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0018 0.0018
Brugia malayi Protein kinase domain containing protein 0.0501 0.2153 0.2153
Echinococcus multilocularis serotonin transporter 0.109 0.4758 0.574
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0209 0.0209
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0209 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0031 0.0071 0.0082
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.003 0.0032
Echinococcus multilocularis geminin 0.0348 0.1474 0.1775
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.0072
Schistosoma mansoni hypothetical protein 0.0022 0.0034 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Echinococcus multilocularis actin binding protein anillin 0.0031 0.0071 0.0082
Brugia malayi vesicular acetylcholine transporter unc-17 0.0877 0.3817 0.3817
Mycobacterium tuberculosis Conserved protein 0.0071 0.0249 0.126
Echinococcus granulosus Pleckstrin y 0.0031 0.0071 0.0082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0142 0.0167
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0097 0.0478
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0209 0.0248
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0035 0.0089 0.0085
Loa Loa (eye worm) hypothetical protein 0.025 0.1043 0.1043
Echinococcus granulosus dna polymerase eta 0.0022 0.003 0.0032
Brugia malayi hypothetical protein 0.0046 0.014 0.014
Giardia lamblia Translation initiation factor eIF-4A, putative 0.025 0.1043 0.2945
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0049 0.0151 0.073
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1302 0.2203
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.1326 0.5804 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0185 0.0753 0.0905
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Brugia malayi bHLH-PAS transcription factor 0.004 0.0111 0.0111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.021 0.8214
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Echinococcus multilocularis Pleckstrin y 0.0031 0.0071 0.0082
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0103 0.164
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0049 0.0151 0.0151
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0216 0.0889 0.1488
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.003 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.014 0.0136
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0122 0.0122
Entamoeba histolytica protein kinase, putative 0.0501 0.2153 0.3677
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0031 0.0071 0.0082
Echinococcus multilocularis dnaJ subfamily B 0.0891 0.3881 0.4681
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0151 0.3307
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.025 0.1043 0.1256
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0035 0.0089 0.0085
Plasmodium falciparum thioredoxin reductase 0.0037 0.0097 0.0706
Echinococcus multilocularis oxysterol binding protein 9 0.0031 0.0071 0.0082
Schistosoma mansoni lamin 0.0028 0.0057 0.0065
Brugia malayi Syntrophin-1 0.0031 0.0071 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.0249
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0027 0.0055 0.0257
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0049 0.0151 0.0179
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0029 0.0031
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.0151
Leishmania major DNA polymerase eta, putative 0.0022 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Brugia malayi hypothetical protein 0.0031 0.0071 0.0071
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0018
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0031 0.0071 0.0082
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1007 0.4392 0.7554
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0031 0.0071 0.0082
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1326 0.5804 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0212 0.0212
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0027 0.0055 0.112
Brugia malayi beta-lactamase 0.0071 0.0249 0.0249
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.3721
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.002 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0029 0.0031
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0027 0.0055 0.0054
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0151 0.1117
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0027 0.0055 0.112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0535 0.2301 0.3934
Schistosoma mansoni vesicular acetylcholine transporter 0.0877 0.3817 0.4603
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0249 0.126
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Schistosoma mansoni hypothetical protein 0.0049 0.0151 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0249 0.0245
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1326 0.5804 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0027 0.0055 0.0257
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0216 0.0889 0.6728
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0035 0.0089 0.0085
Mycobacterium ulcerans putative regulatory protein 0.004 0.0111 0.3707
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0348 0.1768
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0212 0.0252
Plasmodium vivax glutathione reductase, putative 0.0037 0.0097 0.0706
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0122 0.0144
Onchocerca volvulus 0.0028 0.0057 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.011 0.011
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0029 0.0031
Echinococcus multilocularis myotubularin protein 13 0.0031 0.0071 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0214 0.088 0.1472
Trypanosoma brucei trypanothione reductase 0.0037 0.0097 0.0097
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.0753
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0029 0.0031
Leishmania major eukaryotic initiation factor 4a, putative 0.025 0.1043 0.104
Trichomonas vaginalis centaurin/arf, putative 0.0031 0.0071 0.0072
Echinococcus multilocularis Rho GTPase activating protein 24 0.0031 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.014 0.0136
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Brugia malayi hypoxia-induced factor 1 0.0167 0.0673 0.0673
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0053 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Schistosoma mansoni sodium-dependent amino acid transporter 0.0185 0.0753 0.0905
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.0249
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.014 0.1031
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Brugia malayi hypothetical protein 0.0185 0.0753 0.0753
Plasmodium falciparum amino acid transporter, putative 0.0185 0.0753 0.5695
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0162 0.065 0.078
Brugia malayi PHD-finger family protein 0.0029 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Schistosoma mansoni zinc finger protein 0.0031 0.0071 0.0082
Echinococcus multilocularis serine threonine protein kinase 0.0162 0.065 0.078
Echinococcus multilocularis GRB2 associated binding protein 3 0.0031 0.0071 0.0082
Echinococcus granulosus zinc finger protein 0.0024 0.0039 0.0043
Echinococcus granulosus GRB2 associated binding protein 3 0.0031 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.003
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Brugia malayi MAX-1A 0.0031 0.0071 0.0071
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.109 0.4758 0.574
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.003 0.0032
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0027 0.0055 0.0257
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0306 0.1554
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0027 0.0055 0.112
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0216 0.0889 0.1488
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0151 0.0151
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0031 0.0071 0.0071
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0122 0.0144
Entamoeba histolytica PH domain containing protein 0.0031 0.0071 0.0072
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0012 0.001
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0029 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Schistosoma mansoni cytochrome P450 0.0027 0.0055 0.0062
Brugia malayi Oxysterol binding protein 0.0031 0.0071 0.0071
Schistosoma mansoni oxysterol-binding protein 1 0.0031 0.0071 0.0082
Schistosoma mansoni myotubularin-related protein 0.0031 0.0071 0.0082
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.003 0.003
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0151 0.0151
Brugia malayi Cytochrome P450 family protein 0.0056 0.0184 0.0184
Brugia malayi intermediate filament protein 0.0028 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0014 0.001
Echinococcus multilocularis eukaryotic initiation factor 4A 0.025 0.1043 0.1256
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0889 0.0889
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0348 0.1474 0.1775
Trichomonas vaginalis ap endonuclease, putative 0.004 0.011 0.0139
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0111 0.0428 0.0513
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0034 0.022
Trichomonas vaginalis centaurin/arf, putative 0.0031 0.0071 0.0072
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0029 0.0029
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0029 0.0031
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0029 0.0031
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0348 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0111 0.0428 0.0513
Loa Loa (eye worm) hypothetical protein 0.0181 0.0736 0.0736
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0293 0.035
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0049 0.0151 0.0148
Schistosoma mansoni hypothetical protein 0.0175 0.071 0.0853
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0031 0.0071 0.0072
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0185 0.0753 0.0905
Trichomonas vaginalis AGC family protein kinase 0.0162 0.065 0.1073
Onchocerca volvulus 0.004 0.0111 0.0174
Trichomonas vaginalis AGC family protein kinase 0.0192 0.0786 0.131
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0049 0.0151 0.0179
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0027 0.0055 0.0257
Loa Loa (eye worm) hypothetical protein 0.0042 0.0119 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0029 0.0029
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0743 0.3222 0.3222
Loa Loa (eye worm) norepinephrine transporter 0.109 0.4758 0.4758
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0257 0.0307
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0249 0.126
Entamoeba histolytica PH domain containing protein kinase, putative 0.0035 0.0089 0.0102
Echinococcus granulosus intermediate filament protein 0.0028 0.0057 0.0065
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0877 0.3817 0.8009
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.003 0.0131
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0799 0.3471 1
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0031 0.0071 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0031 0.0071 0.0071
Brugia malayi MH2 domain containing protein 0.0131 0.0513 0.0513
Schistosoma mansoni cpg binding protein 0.0068 0.0236 0.0281
Echinococcus granulosus oxysterol binding protein 9 0.0031 0.0071 0.0082
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0162 0.065 0.078
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0027 0.0055 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0173 0.0205
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0184 0.7022
Brugia malayi Bromodomain containing protein 0.008 0.029 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.025 0.1043 0.5356
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0031 0.0071 0.0072
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0122 0.016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.003 0.0131
Toxoplasma gondii hypothetical protein 0.0185 0.0753 0.3721
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0031 0.0071 0.0067
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0257 0.0307
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.021 0.0249
Trypanosoma cruzi target of rapamycin kinase 3 0.0049 0.0151 0.0148
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.021 0.1058
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0029 0.0031
Plasmodium vivax RNA helicase-1, putative 0.025 0.1043 0.7902
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0249 0.0379
Leishmania major DNA polymerase kappa, putative 0.0022 0.003 0.0026
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0005 0.0002
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0216 0.0889 0.1069
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0072 0.0255 0.0255
Brugia malayi PAS domain containing protein 0.0054 0.0173 0.0173
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.1117
Schistosoma mansoni ap endonuclease 0.004 0.011 0.0129
Entamoeba histolytica protein kinase, putative 0.0035 0.0089 0.0102
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0209 0.0205
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0257 0.0307
Leishmania major trypanothione reductase 0.0037 0.0097 0.0094
Schistosoma mansoni lipoxygenase 0.0063 0.0212 0.0252
Echinococcus granulosus serine/threonine protein kinase 0.0344 0.1456 0.1754
Entamoeba histolytica protein kinase, putative 0.047 0.2017 0.344
Echinococcus granulosus vesicular acetylcholine transporter 0.0877 0.3817 0.4603
Toxoplasma gondii target of rapamycin (TOR), putative 0.0049 0.0151 0.073
Echinococcus multilocularis nervana 2 0.0309 0.1302 0.1567
Echinococcus multilocularis pleckstrin y domain containing family A 0.0031 0.0071 0.0082
Echinococcus granulosus lamin dm0 0.0028 0.0057 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.0753
Entamoeba histolytica hypothetical protein 0.1118 0.4883 0.8405
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0041 0.0117 0.0117
Plasmodium falciparum glutathione reductase 0.0037 0.0097 0.0706
Brugia malayi Pleckstrin Homology Domain 0.0031 0.0071 0.0071
Leishmania major cytochrome p450-like protein 0.0027 0.0055 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0029 0.0031
Schistosoma mansoni sodium/chloride dependent transporter 0.0185 0.0753 0.0905
Loa Loa (eye worm) hypothetical protein 0.109 0.4758 0.4758
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0209 0.0248
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0221 0.0263
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Schistosoma mansoni DNA polymerase eta 0.0022 0.003 0.0032
Schistosoma mansoni fkbp-rapamycin associated protein 0.0049 0.0151 0.0179
Loa Loa (eye worm) hypothetical protein 0.0169 0.0683 0.0683
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.0072
Echinococcus granulosus tumor protein p63 0.0282 0.1184 0.1425
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0031 0.0071 0.0082
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0021 0.0028 0.003
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0001
Trypanosoma cruzi PH domain containing protein, putative 0.0031 0.0071 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1302 0.2203
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.011 0.0232
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0049 0.0151 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Echinococcus multilocularis 0.0027 0.0055 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0031 0.0071 0.0082
Entamoeba histolytica ARF GTPase activating protein, putative 0.0031 0.0071 0.0072
Brugia malayi glutathione reductase 0.0037 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0031 0.0071 0.0082
Onchocerca volvulus outspread protein homolog 0.0031 0.0071 0.009
Echinococcus multilocularis dna polymerase kappa 0.0022 0.003 0.0032
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0151 0.0151
Echinococcus granulosus calcium dependent secretion activator 1 0.0031 0.0071 0.0082
Schistosoma mansoni hypothetical protein 0.0081 0.0293 0.035
Echinococcus multilocularis RUN 0.0022 0.0034 0.0037
Plasmodium vivax amine transporter, putative 0.0185 0.0753 0.5695
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0561 0.2417 0.2417
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0216 0.0889 0.6728
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0031 0.0071 0.0507
Onchocerca volvulus 0.0169 0.0683 0.1382
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0424 0.181 0.2181
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0151 0.0151
Schistosoma mansoni lamin 0.0028 0.0057 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Giardia lamblia Phosphatidylinositol 4-kinase 0.0049 0.0151 0.0353
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.011 0.011
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0049 0.0151 0.0148
Loa Loa (eye worm) cytochrome P450 family protein 0.007 0.0242 0.0242
Trypanosoma cruzi PH domain containing protein, putative 0.0031 0.0071 0.0067
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.021 0.102
Brugia malayi Oxysterol-binding protein 0.0031 0.0071 0.0071
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0027 0.0055 0.112
Schistosoma mansoni polycystin 1-related 0.0022 0.0034 0.0037
Echinococcus multilocularis Pleckstrin y 0.0031 0.0071 0.0082
Entamoeba histolytica protein kinase 2, putative 0.0313 0.1319 0.2233
Giardia lamblia GTOR 0.0049 0.0151 0.0353
Leishmania major hypothetical protein, unknown function 0.0049 0.0151 0.0148
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0049 0.0151 0.0151
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0249 0.0379
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0027 0.0055 0.0257
Loa Loa (eye worm) hypothetical protein 0.0081 0.0293 0.0293
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.1162 0.5079 0.5079
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0029 0.0031
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0029 0.0031
Schistosoma mansoni goodpasture antigen-binding protein 0.0031 0.0071 0.0082
Entamoeba histolytica protein kinase, putative 0.0035 0.0089 0.0102
Brugia malayi Pax transcription factor protein 2 0.0248 0.1035 0.1035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Leishmania major cytochrome p450-like protein 0.0027 0.0055 0.0051
Schistosoma mansoni hypothetical protein 0.0031 0.0071 0.0082
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0049 0.0151 0.073
Brugia malayi N-terminal motif family protein 0.0185 0.0752 0.0752
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0049 0.0151 0.021
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0035 0.0089 0.0085
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0035 0.0089 0.0642
Entamoeba histolytica protein kinase rad3, putative 0.0049 0.0151 0.021
Plasmodium falciparum eukaryotic initiation factor 4A 0.025 0.1043 0.7902
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0049 0.0151 0.0179
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0743 0.3222 0.3886
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0049 0.0151 0.1117
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1887 0.8287 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0029 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0029 0.0031
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0348 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0122 0.4212
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.011 0.0106
Onchocerca volvulus 0.0185 0.0753 0.1532
Brugia malayi hypothetical protein 0.0727 0.3151 0.3151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Echinococcus granulosus protein kinase c iota type 0.0162 0.065 0.078
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0877 0.3817 0.3817
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Echinococcus granulosus cytohesin 1 0.0031 0.0071 0.0082
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0249 0.126
Loa Loa (eye worm) Plekhf2 protein 0.0031 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Schistosoma mansoni vav2 0.0031 0.0071 0.0082
Mycobacterium tuberculosis Conserved hypothetical protein 0.0049 0.0151 0.0757
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0513 0.0513
Leishmania major phosphatidylinositol kinase related protein, putative 0.0049 0.0151 0.0148
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0293 0.0293
Loa Loa (eye worm) serotonin transporter b 0.109 0.4758 0.4758
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0031 0.0071 0.009
Trichomonas vaginalis centaurin beta, putative 0.0031 0.0071 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0151 0.021
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0035 0.0089 0.0089
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0348 0.1768
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0027 0.0055 0.0257
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0053 0.0059
Brugia malayi Bromodomain containing protein 0.0039 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0111 0.013
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0162 0.065 0.078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0109 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0031 0.0071 0.0072
Echinococcus multilocularis protein kinase c iota type 0.0162 0.065 0.078
Entamoeba histolytica protein kinase, putative 0.0501 0.2153 0.3677
Trichomonas vaginalis centaurin alpha, putative 0.0031 0.0071 0.0072
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.01 0.0116
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0344 0.1456 0.1453
Echinococcus granulosus protein kinase c epsilon type 0.0162 0.065 0.078
Trichomonas vaginalis glucosylceramidase, putative 0.0214 0.088 0.1472
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0142 0.0167
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0151 0.0179
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0029 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.011 0.0139
Schistosoma mansoni inositol monophosphatase 0.0042 0.0122 0.0144
Schistosoma mansoni serine/threonine kinase 0.0162 0.065 0.078
Loa Loa (eye worm) beta-lactamase 0.0071 0.0249 0.0249
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0027 0.0028
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0122 0.016
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.011 0.0802
Toxoplasma gondii exonuclease III APE 0.004 0.011 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) hypothetical protein 0.0047 0.0144 0.0144
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0293 0.035
Plasmodium vivax PH domain containing protein 0.0031 0.0071 0.0507
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.003 0.0026
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0185 0.0753 0.5
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0151 0.0148
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0027 0.0055 0.112
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0049 0.0151 0.0179
Leishmania major hypothetical protein, conserved 0.0031 0.0071 0.0067
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Schistosoma mansoni inositol monophosphatase 0.0042 0.0122 0.0144
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0035 0.0089 0.0085
Echinococcus multilocularis tumor protein p63 0.0282 0.1184 0.1425
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0249 0.6637
Echinococcus granulosus beta 1 syntrophin 0.0031 0.0071 0.0082
Schistosoma mansoni hypothetical protein 0.0081 0.0293 0.035
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0031 0.0071 0.0082
Echinococcus multilocularis dynamin 1 0.0031 0.0071 0.0082
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0005 0.0005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0249 0.126
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0185 0.0753 0.0905
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0454 0.1944 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0309 0.1302 0.1302
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0027 0.0055 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0029 0.0031
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0028 0.0028
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0184 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Schistosoma mansoni loxhd1 0.0022 0.0034 0.0037
Echinococcus multilocularis Glutaredoxin protein 5 0.0309 0.1304 0.157
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0035 0.0089 0.0089
Entamoeba histolytica hypothetical protein 0.0073 0.0257 0.0394
Onchocerca volvulus Putative zinc finger protein 0.0031 0.0071 0.009
Trichomonas vaginalis AGC family protein kinase 0.0501 0.2153 0.3677
Brugia malayi hypothetical protein 0.0169 0.0683 0.0683
Onchocerca volvulus 0.0031 0.0071 0.009
Echinococcus multilocularis serine protein kinase ATM 0.0049 0.0151 0.0179
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.014 0.014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0256 0.1069 0.1069
Schistosoma mansoni sodium/chloride dependent transporter 0.0189 0.0771 0.0927
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0889 0.0886
Schistosoma mansoni zinc finger protein 0.0024 0.0039 0.0043
Brugia malayi Cytochrome P450 family protein 0.0056 0.0184 0.0184
Echinococcus multilocularis serine:threonine protein kinase 38 0.0162 0.065 0.078
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1302 0.2203
Loa Loa (eye worm) cytochrome P450 0.0027 0.0055 0.0055
Brugia malayi Dynamin 0.0031 0.0071 0.0071
Echinococcus granulosus single minded 2 0.004 0.0111 0.013
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0031 0.0071 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Brugia malayi PH domain containing protein 0.0031 0.0071 0.0071
Echinococcus granulosus nervana 2 0.0309 0.1302 0.1567
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0306 0.1554
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0309 0.1302 0.1567
Brugia malayi protein kinase C II. 0.0162 0.065 0.065
Schistosoma mansoni rho gtpase activating protein 0.0031 0.0071 0.0082
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0151 0.0151
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0743 0.3222 0.3886
Echinococcus multilocularis Pleckstrin y 0.0031 0.0071 0.0082
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0027 0.0055 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0018 0.0018
Onchocerca volvulus 0.0148 0.0591 0.1188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0029
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0027 0.0055 0.112
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0313 0.1319 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0029 0.0029
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0049 0.0151 0.0179
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0424 0.181 0.181
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Mycobacterium ulcerans lipase LipD 0.0071 0.0249 1
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0049 0.0151 0.0148
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0249 0.1859
Onchocerca volvulus 0.0031 0.0071 0.009
Loa Loa (eye worm) hypoxia-induced factor 1 0.0167 0.0673 0.0673
Brugia malayi Cadps2 protein 0.0031 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0175 0.071 0.071
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0049 0.0151 0.0151
Mycobacterium tuberculosis Conserved protein 0.0071 0.0249 0.126
Loa Loa (eye worm) hypothetical protein 0.0101 0.0383 0.0383
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0034 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0216 0.0889 0.1488
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0049 0.0151 0.0148
Brugia malayi Inositol-1 0.0042 0.0122 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0027 0.0055 0.0257
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0209 0.0205
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0031 0.0071 0.0072
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0142 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0209 0.031
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1302 0.2203
Toxoplasma gondii hypothetical protein 0.0031 0.0071 0.0331
Echinococcus granulosus lamin 0.0028 0.0057 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0071 0.0249 0.0245
Trypanosoma brucei unspecified product 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0162 0.065 0.065
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0005 0.0002
Echinococcus granulosus Pleckstrin y 0.0031 0.0071 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.025 0.1043 0.1256
Schistosoma mansoni hypothetical protein 0.0031 0.0071 0.0082
Schistosoma mansoni sodium/chloride dependent transporter 0.109 0.4758 0.574
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0049 0.0151 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0029 0.0029
Schistosoma mansoni rab6-interacting 0.0022 0.0034 0.0037
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0249 0.0379
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0249 0.0297
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0057 0.0057
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0142 0.0142
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0293 0.035
Onchocerca volvulus 0.0031 0.0071 0.009
Onchocerca volvulus 0.0071 0.0249 0.0465
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0591 0.0591
Giardia lamblia Kinase, AGC PKA 0.0313 0.1319 0.3747
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0162 0.065 0.078
Loa Loa (eye worm) cytohesin 3 0.0031 0.0071 0.0071
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0097 0.0097
Leishmania major protein kinase, putative 0.0018 0.0014 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0151 0.0148
Trypanosoma cruzi Protein kinase B 0.0344 0.1456 0.1453
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0031 0.0071 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0029 0.0029
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0184 0.0184
Loa Loa (eye worm) solute carrier family 6 member 4 0.109 0.4758 0.4758
Trypanosoma cruzi hypothetical protein 0.0031 0.0071 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.011 0.3652
Entamoeba histolytica protein kinase, putative 0.0035 0.0089 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0027 0.0055 0.0257
Entamoeba histolytica hypothetical protein 0.0035 0.0089 0.0102
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0027 0.0055 0.112
Loa Loa (eye worm) uncoordinated protein 104 0.0031 0.0071 0.0071
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0035 0.0089 0.0085
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.025 0.1043 0.104
Plasmodium falciparum PH domain-containing protein, putative 0.0031 0.0071 0.0507
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1007 0.4392 0.7554
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0027 0.0055 0.112
Brugia malayi hypothetical protein 0.0022 0.0034 0.0034
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.003 0.003
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0049 0.0151 0.1117
Leishmania major phosphatidylinositol 3-kinase, putative 0.0216 0.0889 0.0886
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0293 0.035
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0049 0.0151 0.0148
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0424 0.181 0.3083
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0185 0.0753 0.0905
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0151 0.0151
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0185 0.0753 0.3721
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0031 0.0071 0.0507
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0053 0.0059
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0027 0.0055 0.112
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0049 0.0151 0.0148
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Echinococcus multilocularis dna polymerase eta 0.0022 0.003 0.0032
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.1277 0.5587 0.9624
Loa Loa (eye worm) hypothetical protein 0.0049 0.0151 0.0151
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Trichomonas vaginalis AGC family protein kinase 0.0162 0.065 0.1073
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0097 0.0114
Brugia malayi Cytochrome P450 family protein 0.007 0.0242 0.0242
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0034
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0027 0.0055 0.0257
Loa Loa (eye worm) nuclear hormone receptor 0.01 0.0378 0.0378
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0209 0.031
Leishmania major eukaryotic initiation factor 4a, putative 0.025 0.1043 0.104
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0031 0.0071 0.0507
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1302 0.2203
Echinococcus multilocularis serine:threonine protein kinase N2 0.0162 0.065 0.078
Entamoeba histolytica PH domain containing protein kinase, putative 0.0035 0.0089 0.0102
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0209 0.0205
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Echinococcus granulosus serine threonine protein kinase nrc 0.0313 0.1319 0.1589
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0031 0.0071 0.0082
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0184 0.0183
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0249 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0014 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0031 0.0071 0.0507
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0031 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.0249
Leishmania major hypothetical protein, conserved 0.0049 0.0151 0.0148
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0151 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Echinococcus granulosus sodium and chloride dependent glycine 0.0185 0.0753 0.0905
Echinococcus granulosus dynamin 1 0.0031 0.0071 0.0082
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0029 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Schistosoma mansoni single-minded 0.0054 0.0173 0.0205
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0027 0.0055 0.112
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0151 0.0151
Brugia malayi Cytohesin 3 0.0031 0.0071 0.0071
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0049 0.0151 0.0179
Trichomonas vaginalis alpha chimerin, putative 0.0031 0.0071 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0027 0.0055 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0029 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0027 0.0055 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.065 0.078
Brugia malayi Protein kinase domain containing protein 0.0162 0.065 0.065
Echinococcus granulosus dnaJ subfamily B 0.0891 0.3881 0.4681
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.011 0.0543
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0029 0.0029
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.003 0.0032
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0029 0.0029
Leishmania major protein kinase, putative 0.0035 0.0089 0.0085
Schistosoma mansoni dynamin 0.0031 0.0071 0.0082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1326 0.5804 0.5804
Loa Loa (eye worm) hypothetical protein 0.0185 0.0753 0.0753
Entamoeba histolytica protein kinase, putative 0.0162 0.065 0.1073
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0424 0.181 0.1807
Plasmodium vivax hypothetical protein, conserved 0.0185 0.0753 0.5695
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0027 0.0055 0.0257
Brugia malayi nuclear hormone receptor 0.0021 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0071 0.0071
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0122 0.016
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.011 0.0129
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0027 0.0055 0.112
Schistosoma mansoni zinc finger protein 0.0016 0.0004 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0029 0.0029
Echinococcus granulosus pdz domain containing protein 0.0031 0.0071 0.0082
Leishmania major phosphatidylinositol kinase, putative 0.0049 0.0151 0.0148
Loa Loa (eye worm) rho-GTPase-activating 0.0031 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) AGC/AKT protein kinase 0.0501 0.2153 0.2153
Trypanosoma brucei protein kinase, putative 0.0062 0.0209 0.0209
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0216 0.0889 0.1069
Onchocerca volvulus 0.0071 0.0249 0.0465
Onchocerca volvulus 0.0031 0.0071 0.009
Echinococcus multilocularis oxysterol binding protein 1 0.0031 0.0071 0.0082
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0027 0.0055 0.112
Treponema pallidum sodium- and chloride- dependent transporter 0.109 0.4758 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0122 0.0118
Brugia malayi latrophilin 2 splice variant baaae 0.0175 0.071 0.071
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0184 0.018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0027 0.0028
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0035 0.0089 0.0085
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.003 0.003
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0313 0.1319 0.1589
Echinococcus granulosus RUN 0.0022 0.0034 0.0037
Trypanosoma cruzi NIMA-related kinase, putative 0.0035 0.0089 0.0085
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.003 0.0026
Loa Loa (eye worm) oxysterol binding protein 0.0031 0.0071 0.0071
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0029 0.0031
Echinococcus granulosus Protein kinase C brain isozyme 0.0162 0.065 0.078
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0249 0.0249
Entamoeba histolytica hypothetical protein 0.0073 0.0257 0.0394
Leishmania major phosphatidylinositol 3-kinase, putative 0.0049 0.0151 0.0148
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0185 0.0753 0.0905
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1326 0.5804 0.5803
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0049 0.0151 0.0179
Schistosoma mansoni hypothetical protein 0.0021 0.0027 0.0028
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0162 0.065 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0162 0.065 0.065
Echinococcus granulosus serine protein kinase ATM 0.0049 0.0151 0.0179
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0212 0.0252
Schistosoma mansoni cpg binding protein 0.0063 0.0212 0.0251
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0031 0.0071 0.0072
Onchocerca volvulus 0.0185 0.0753 0.1532
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0029 0.0031
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0209 0.0248
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0162 0.065 0.078
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1887 0.8287 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0424 0.181 0.3083
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.003 0.003
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0089 0.0102
Entamoeba histolytica hypothetical protein 0.0049 0.0151 0.021
Schistosoma mansoni hypothetical protein 0.0073 0.0257 0.0307
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.014 0.1031
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0049 0.0151 0.0151
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0055 0.0051
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0035 0.0089 0.0089
Entamoeba histolytica hypothetical protein 0.0031 0.0071 0.0072
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0027 0.0055 0.112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Loa Loa (eye worm) AGC/PKN protein kinase 0.0162 0.065 0.065
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0249 1
Echinococcus granulosus serine:threonine protein kinase N2 0.0162 0.065 0.078
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0185 0.0753 0.0905
Echinococcus granulosus cytochrome P450 2K1 0.0027 0.0055 0.0062
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0031 0.0071 0.0082
Trypanosoma brucei PH domain containing protein, putative 0.0031 0.0071 0.0071
Schistosoma mansoni intermediate filament proteins 0.0028 0.0057 0.0065
Loa Loa (eye worm) hypothetical protein 0.0049 0.0151 0.0151
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.021 0.8214
Brugia malayi Uncoordinated protein 104 0.0031 0.0071 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0249 0.0379
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0249 0.0245
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0031 0.0071 0.0507
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0424 0.181 0.3083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0151 0.021
Schistosoma mansoni growth factor receptor-bound protein 0.0031 0.0071 0.0082
Echinococcus granulosus dna polymerase kappa 0.0022 0.003 0.0032
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0097 0.0706
Trichomonas vaginalis glucosylceramidase, putative 0.0203 0.0832 0.1389
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.025 0.1043 0.1755
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0071 0.0072
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0029 0.0031

Activities

Activity type Activity value Assay description Source Reference
Drug uptake (ADMET) = 1.13 % ID/g Biodistribution in ddY mouse bone at 18.5 kBq, iv after 2 mins ChEMBL. 19201614
Drug uptake (ADMET) = 1.65 % ID/g Biodistribution in ddY mouse bone at 18.5 kBq, iv after 10 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2 % ID/g Biodistribution in ddY mouse brain at 18.5 kBq, iv after 30 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.09 % ID/g Biodistribution in ddY mouse blood at 18.5 kBq, iv after 2 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.13 % ID/g Biodistribution in ddY mouse brain at 18.5 kBq, iv after 60 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.3 % ID/g Biodistribution in ddY mouse blood at 18.5 kBq, iv after 10 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.42 % ID/g Biodistribution in ddY mouse bone at 18.5 kBq, iv after 30 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.5 % ID/g Biodistribution in ddY mouse blood at 18.5 kBq, iv after 30 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.75 % ID/g Biodistribution in ddY mouse brain at 18.5 kBq, iv after 10 mins ChEMBL. 19201614
Drug uptake (ADMET) = 2.94 % ID/g Biodistribution in ddY mouse blood at 18.5 kBq, iv after 60 mins ChEMBL. 19201614
Drug uptake (ADMET) = 3.54 % ID/g Biodistribution in ddY mouse brain at 18.5 kBq, iv after 2 mins ChEMBL. 19201614
Drug uptake (ADMET) = 3.74 % ID/g Biodistribution in ddY mouse bone at 18.5 kBq, iv after 60 mins ChEMBL. 19201614

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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