Detailed information for compound 275311

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 411.943 | Formula: C24H27ClFN3
  • H donors: 0 H acceptors: 0 LogP: 5.34 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1Cl)N1CCN(CC1)CCc1c(C)n2c3c1cccc3CCC2
  • InChi: 1S/C24H27ClFN3/c1-17-20(21-6-2-4-18-5-3-10-29(17)24(18)21)9-11-27-12-14-28(15-13-27)19-7-8-23(26)22(25)16-19/h2,4,6-8,16H,3,5,9-15H2,1H3
  • InChiKey: KHFQFCCAORBSOY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0019 0.0921
Echinococcus multilocularis Tubulin alpha 1 chain 0.0181 0.0108 0.0107
Echinococcus granulosus chromobox protein 1 0.0051 0.002 0.0019
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0023 0.0001 0.0008
Echinococcus granulosus g protein coupled receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis lamin 0.0115 0.0063 0.0062
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0002 0.0076
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.053 0.0343 0.0706
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Trypanosoma brucei isocitrate dehydrogenase, putative 0.015 0.0087 0.42
Schistosoma mansoni myelin transcription factor 1 myt1 0.0044 0.0015 0.0025
Mycobacterium leprae Conserved hypothetical protein 0.0068 0.0031 0.006
Schistosoma mansoni hypothetical protein 0.0217 0.0132 0.0232
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0545 0.0354 0.0624
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0019 0.0921
Wolbachia endosymbiont of Brugia malayi carbonic anhydrase 0.0034 0.0009 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0523 0.0339 0.1862
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0079 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.0062 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0001 0.0003
Plasmodium falciparum pyruvate kinase 2 0.0045 0.0016 0.0868
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0523 0.0339 0.0338
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0222 0.0136 0.0744
Echinococcus granulosus somatostatin receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis serotonin receptor 0.0303 0.019 0.0189
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0009 0.0086
Loa Loa (eye worm) nuclear receptor NHR-67 0.0457 0.0294 0.1616
Schistosoma mansoni neuropeptide f receptor 76f 0.0217 0.0132 0.0232
Trichomonas vaginalis pyruvate kinase, putative 0.0088 0.0045 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.005 0.0019 0.0105
Mycobacterium leprae Probable lipase LipE 0.0113 0.0062 0.0123
Echinococcus granulosus RUN 0.0028 0.0005 0.0003
Loa Loa (eye worm) tubulin beta-4 chain 0.0265 0.0165 0.0904
Schistosoma mansoni hypothetical protein 0.024 0.0148 0.0259
Plasmodium falciparum pyruvate kinase 0.0088 0.0045 0.2639
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Brugia malayi Serotonin receptor 0.0217 0.0132 0.0727
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0029 0.0005 0.0007
Trypanosoma brucei cAMP-specific phosphodiesterase 0.005 0.0019 0.0851
Brugia malayi CXXC zinc finger family protein 0.0115 0.0063 0.0346
Loa Loa (eye worm) MH2 domain-containing protein 0.0567 0.0369 0.2024
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0009 0.0423
Loa Loa (eye worm) hypothetical protein 0.04 0.0256 0.1404
Trypanosoma brucei unspecified product 0.0035 0.0009 0.0368
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0217 0.0132 0.0232
Schistosoma mansoni hypothetical protein 0.0869 0.0573 0.101
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0029 0.0005 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0217 0.0132 0.0131
Onchocerca volvulus Bile acid receptor homolog 0.1201 0.0797 0.8068
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0029 0.0005 0.0007
Trichomonas vaginalis sugar-1-phosphate guanyl transferase, putative 0.0035 0.0009 0.0093
Loa Loa (eye worm) tubulin gamma chain 0.0135 0.0077 0.0423
Echinococcus multilocularis Tubulin beta 2C chain 0.0265 0.0165 0.0164
Brugia malayi intermediate filament protein 0.0115 0.0063 0.0348
Schistosoma mansoni tubulin subunit beta 0.0059 0.0025 0.0043
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0013 0.0131
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0038 0.0011 0.0018
Onchocerca volvulus 0.0028 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0023 0.0001 0.0008
Schistosoma mansoni terminal deoxycytidyl transferase 0.0051 0.002 0.0033
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0029 0.0005 0.0004
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0523 0.0339 0.0338
Schistosoma mansoni hypothetical protein 0.0124 0.0069 0.012
Trichomonas vaginalis tubulin epsilon chain, putative 0.0059 0.0025 0.0253
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0108 0.0058 0.3479
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0044 0.0015 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0019 0.0921
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.0062 0.034
Schistosoma mansoni ap endonuclease 0.0034 0.0009 0.0013
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Toxoplasma gondii GDP-D-mannose pyrophosphorylase 0.0035 0.0009 0.0083
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0029 0.0005 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0004 0.0205
Toxoplasma gondii LsmAD domain-containing protein 0.0069 0.0033 0.0336
Schistosoma mansoni neuropeptide receptor 0.0217 0.0132 0.0232
Schistosoma mansoni tar DNA-binding protein 0.0105 0.0057 0.0098
Echinococcus multilocularis tubulin alpha 3 chain 0.0181 0.0108 0.0107
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0009 0.034
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0322 0.0203 0.2052
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0027
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Schistosoma mansoni tubulin subunit beta 0.0265 0.0165 0.0289
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0002 0.0076
Schistosoma mansoni hypothetical protein 0.0287 0.0179 0.0315
Schistosoma mansoni alpha tubulin 0.0181 0.0108 0.0188
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0035 0.0009 0.005
Onchocerca volvulus Pyruvate kinase homolog 0.0088 0.0045 0.0447
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0068 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0034 0.0009 0.0048
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0068 0.0031 0.0061
Schistosoma mansoni adenoreceptor 0.0217 0.0132 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0222 0.0136 0.1369
Mycobacterium ulcerans hypothetical protein 0.0113 0.0062 0.0124
Echinococcus multilocularis pyruvate kinase 0.0088 0.0045 0.0044
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.0062 0.0624
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0034 0.0009 0.0008
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0038 0.0011 0.0109
Echinococcus multilocularis tubulin alpha chain 0.0181 0.0108 0.0107
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0029 0.0005 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Trypanosoma brucei beta tubulin 0.0135 0.0077 0.3716
Trypanosoma cruzi alpha tubulin, putative 0.0181 0.0108 0.5266
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0104 0.0056 0.0563
Schistosoma mansoni loxhd1 0.0028 0.0005 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0025 0.0253
Loa Loa (eye worm) histone methyltransferase 0.0042 0.0014 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0222 0.0136 0.0744
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Echinococcus multilocularis dro:myosuppressin receptor 0.0217 0.0132 0.0131
Toxoplasma gondii eukaryotic initiation factor 2B epsilon subunit, putative 0.0034 0.0009 0.0076
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0029 0.0005 0.0243
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0034 0.0009 0.0014
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0217 0.0132 0.0232
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Schistosoma mansoni amine GPCR 0.0217 0.0132 0.0232
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0217 0.0132 0.0131
Leishmania major gamma-tubulin 0.0135 0.0077 0.2237
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.005 0.002 0.0018
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0028 0.0004 0.0025
Echinococcus multilocularis Tubulin beta 2C chain 0.0265 0.0165 0.0164
Schistosoma mansoni tubulin subunit beta 0.0265 0.0165 0.0289
Entamoeba histolytica tubulin alpha chain, putative 0.0181 0.0108 0.6533
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0028 0.0004 0.013
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0028 0.0004 0.0205
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0217 0.0132 0.0131
Echinococcus multilocularis sex peptide receptor 0.0217 0.0132 0.0131
Trichomonas vaginalis tubulin epsilon chain, putative 0.0265 0.0165 0.1665
Echinococcus granulosus SAM and MBT domain containing protein 0.0038 0.0011 0.001
Echinococcus multilocularis g protein coupled receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis tar DNA binding protein 0.0105 0.0057 0.0055
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0029 0.0005 0.0302
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0029
Trypanosoma brucei tubulin gamma chain 0.0135 0.0077 0.3716
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0019 0.019
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0002 0.0014
Echinococcus granulosus fmrfamide receptor 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0035 0.0009 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0034 0.0009 0.0414
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0407 0.0261 0.026
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0029 0.0005 0.0243
Brugia malayi nuclear receptor RXR 0.0457 0.0294 0.1616
Echinococcus granulosus tubulin alpha chain 0.0181 0.0108 0.0107
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.0062 0.0124
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0251 0.0155 0.0853
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0009 0.0086
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.0062 0.2967
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.005 0.0019 0.0921
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1847 0.1234 0.1233
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0217 0.0132 0.0131
Plasmodium vivax mannose-1-phosphate guanyltransferase, putative 0.0035 0.0009 0.0466
Loa Loa (eye worm) PDE1B protein 0.005 0.0019 0.0105
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0023 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0217 0.0132 0.0131
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0016
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0071 0.0033 0.0065
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.7181 0.4838 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0034 0.0009 0.0014
Onchocerca volvulus 0.0115 0.0063 0.0635
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0002 0.0076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0009 0.0015
Echinococcus granulosus lamin dm0 0.0115 0.0063 0.0062
Trypanosoma cruzi epsilon tubulin, putative 0.0135 0.0077 0.3764
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0029 0.0005 0.0243
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0034 0.0009 0.0013
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0029 0.0005 0.0007
Entamoeba histolytica hypothetical protein 0.0124 0.0069 0.4194
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0114 0.0063 0.2999
Schistosoma mansoni neuropeptide receptor 0.0217 0.0132 0.0232
Mycobacterium tuberculosis Probable dehydrogenase 0.0159 0.0093 0.0188
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0055 0.0023 0.0038
Brugia malayi Tubulin beta-1 chain 0.0265 0.0165 0.0904
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0034 0.0009 0.0514
Leishmania major DNA polymerase kappa, putative 0.0051 0.002 0.0574
Plasmodium vivax glutathione reductase, putative 0.007 0.0033 0.1885
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Loa Loa (eye worm) hypothetical protein 0.0055 0.0023 0.0124
Plasmodium falciparum glutathione reductase 0.007 0.0033 0.1885
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0122 0.0068 0.0685
Entamoeba histolytica acetyltransferase, putative 0.0034 0.0009 0.0514
Brugia malayi RE15519p 0.0217 0.0132 0.0727
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.098 0.0648 0.0647
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.0062 0.0124
Echinococcus multilocularis protein patched 0.0039 0.0012 0.0011
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0003 0.0016
Echinococcus granulosus cpg binding protein 0.0122 0.0068 0.0067
Schistosoma mansoni alpha tubulin 0.0181 0.0108 0.0188
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0023 0.0001 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0189 0.0113 0.0198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Trypanosoma cruzi trypanothione reductase, putative 0.007 0.0033 0.1582
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0068 0.0032 0.0911
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.053 0.0343 0.0342
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0457 0.0294 0.0293
Entamoeba histolytica translation initiation factor eIF-2B epsilon subunit, putative 0.0035 0.0009 0.0556
Onchocerca volvulus 0.0028 0.0005 0.0039
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0407 0.0261 0.026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0202 0.0122 0.0213
Brugia malayi cytochrome P450 0.0068 0.0031 0.0172
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0013 0.0634
Echinococcus granulosus tubulin alpha 3 chain 0.0181 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0027
Echinococcus granulosus neuropeptide Y receptor 0.0217 0.0132 0.0131
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0217 0.0132 0.0131
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Toxoplasma gondii exonuclease III APE 0.0034 0.0009 0.0076
Echinococcus multilocularis neuropeptide Y receptor 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0028 0.0005 0.0025
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0176 0.0105 0.0213
Onchocerca volvulus 0.0217 0.0132 0.1334
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0005 0.0007
Echinococcus multilocularis conserved hypothetical protein 0.0486 0.0314 0.0313
Brugia malayi hypothetical protein 0.0028 0.0005 0.0025
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0079 0.0039 0.0038
Schistosoma mansoni glucosamine-1-phosphate N-acetyltransferase 0.0035 0.0009 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.098 0.0648 0.3557
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus tm gpcr rhodopsin 0.0217 0.0132 0.0131
Giardia lamblia Beta tubulin 0.0265 0.0165 0.6288
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.098 0.0648 0.3557
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0105
Trypanosoma cruzi epsilon tubulin, putative 0.0135 0.0077 0.3764
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0217 0.0132 0.0131
Trypanosoma cruzi tubulin gamma chain 0.0135 0.0077 0.3764
Schistosoma mansoni nuclear receptor 0.0457 0.0294 0.0518
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0523 0.0339 0.0597
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0029 0.0005 0.0168
Plasmodium vivax tubulin alpha chain, putative 0.0181 0.0108 0.65
Echinococcus multilocularis dnaJ subfamily B 0.0803 0.0528 0.0527
Echinococcus granulosus importin subunit beta 1 0.0027 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0222 0.0135 0.0743
Brugia malayi nuclear hormone receptor 0.0457 0.0294 0.1616
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0062 0.3021
Brugia malayi Latrophilin receptor protein 2 0.0402 0.0257 0.1413
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0071 0.0033 0.0065
Trypanosoma cruzi serine acetyltransferase, putative 0.0034 0.0009 0.0414
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0029 0.0005 0.0243
Onchocerca volvulus 0.0113 0.0062 0.062
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis glucosylceramidase, putative 0.0222 0.0136 0.1369
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.005 0.0019 0.0851
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0068 0.0031 0.0061
Brugia malayi N-terminal motif family protein 0.0322 0.0203 0.1117
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0009 0.0414
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0068 0.0031 0.0061
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0483 0.0312 0.0311
Echinococcus granulosus Polycystic kidney disease protein 0.0028 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0008
Plasmodium falciparum mannose-1-phosphate guanyltransferase, putative 0.0035 0.0009 0.0466
Schistosoma mansoni tar DNA-binding protein 0.0105 0.0057 0.0098
Schistosoma mansoni histamine h1 receptor 0.0217 0.0132 0.0232
Schistosoma mansoni tar DNA-binding protein 0.0105 0.0057 0.0098
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Mycobacterium tuberculosis Conserved hypothetical protein 0.1252 0.0832 0.1716
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.015 0.0087 0.2522
Schistosoma mansoni hypothetical protein 0.0031 0.0007 0.001
Plasmodium falciparum importin beta, putative 0.0027 0.0004 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0076
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.1058
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0034 0.0009 0.0514
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0402 0.0257 0.1413
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.0062 0.0124
Echinococcus granulosus tachykinin peptides receptor 99D 0.0217 0.0132 0.0131
Trichomonas vaginalis glucose-1-phosphate thymidylyltransferase, putative 0.0035 0.0009 0.0093
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0029 0.0005 0.0243
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0009 0.0414
Entamoeba histolytica deoxycytidyl transferase, putative 0.0051 0.002 0.1197
Brugia malayi Intermediate filament tail domain containing protein 0.0115 0.0063 0.0348
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Brugia malayi gamma-secretase subunit aph-1 0.0831 0.0547 0.3003
Echinococcus granulosus dro:myosuppressin receptor 0.0217 0.0132 0.0131
Brugia malayi Pyruvate kinase, muscle isozyme 0.0088 0.0045 0.0246
Mycobacterium leprae cell division protein FtsZ 0.0059 0.0025 0.0047
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0002 0.0045
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0023 0.0001 0.0011
Toxoplasma gondii hypothetical protein 0.0028 0.0004 0.0029
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.0851
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0002 0.0001
Trypanosoma brucei unspecified product 0.0051 0.002 0.0896
Loa Loa (eye worm) hypothetical protein 0.0053 0.0022 0.0119
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0523 0.0339 0.0597
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0034 0.0009 0.0246
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0005 0.0007
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0005 0.0042
Brugia malayi G protein-coupled receptor 0.0217 0.0132 0.0727
Echinococcus granulosus neuropeptide s receptor 0.2734 0.1833 0.1832
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Loa Loa (eye worm) doublecortin family protein 0.0028 0.0005 0.0025
Loa Loa (eye worm) pyruvate kinase 0.0088 0.0045 0.0246
Loa Loa (eye worm) hypothetical protein 0.0523 0.0339 0.1862
Onchocerca volvulus 0.0217 0.0132 0.1334
Schistosoma mansoni hypothetical protein 0.0402 0.0257 0.0453
Echinococcus multilocularis tubulin subunit beta 0.0265 0.0165 0.0164
Echinococcus granulosus lipoxygenase domain containing protein 0.0028 0.0005 0.0003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0055 0.0023 0.1028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0409 0.0262 0.2853
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.0851
Trichomonas vaginalis tubulin beta chain, putative 0.0265 0.0165 0.1665
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.0062 0.0061
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0122 0.0068 0.0373
Toxoplasma gondii alpha-tubulin I, putative 0.0181 0.0108 0.1161
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0029 0.0005 0.0007
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0034 0.0009 0.0014
Leishmania major hypothetical protein, conserved 0.0034 0.0009 0.0246
Echinococcus multilocularis allatostatin A receptor 0.0217 0.0132 0.0131
Brugia malayi putative neuropeptide receptor NPR1 0.0217 0.0132 0.0727
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1271 0.0844 0.4636
Trypanosoma brucei alpha tubulin 0.0181 0.0108 0.523
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0035 0.0009 0.0008
Schistosoma mansoni neuropeptide receptor 0.0217 0.0132 0.0232
Echinococcus multilocularis neuropeptide Y receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0202 0.0122 0.0121
Leishmania major hypothetical protein, conserved 0.0034 0.0009 0.0246
Brugia malayi chromobox protein homolog 3 0.0029 0.0005 0.0027
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.098 0.0648 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0019 0.019
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Schistosoma mansoni mixed-lineage leukemia protein mll 0.025 0.0154 0.0271
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0002 0.0063
Schistosoma mansoni retinoid-x-receptor (RXR) 0.098 0.0648 0.1143
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0059 0.0025 0.0253
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0009 0.0368
Echinococcus granulosus alpha 1A adrenergic receptor 0.0217 0.0132 0.0131
Leishmania major GDP-mannose pyrophosphorylase 0.0035 0.0009 0.0266
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0068 0.0031 0.0061
Brugia malayi MH2 domain containing protein 0.0039 0.0012 0.0064
Brugia malayi Inositol-1 0.0041 0.0013 0.0073
Schistosoma mansoni tubulin subunit delta 0.0059 0.0025 0.0043
Echinococcus multilocularis tubulin alpha chain 0.0181 0.0108 0.0107
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0002 0.0014
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0029 0.0005 0.0007
Schistosoma mansoni steroid hormone receptor ad4bp 0.098 0.0648 0.1143
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0032 0.0316
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Echinococcus granulosus Tubulin alpha 1 chain 0.0181 0.0108 0.0107
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.098 0.0648 0.1143
Loa Loa (eye worm) steroid hormone receptor 0.1186 0.0787 0.4323
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0031 0.0007 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.0303 0.019 0.0189
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.0062 0.034
Echinococcus multilocularis dna polymerase eta 0.0051 0.002 0.0019
Trypanosoma cruzi PAB1-binding protein , putative 0.0069 0.0033 0.158
Echinococcus multilocularis tubulin subunit TubB 0.0181 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0088 0.0045 0.0246
Echinococcus multilocularis muscleblind protein 0.0267 0.0166 0.0165
Echinococcus granulosus snurportin 1 0.0287 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0251 0.0155 0.0853
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Onchocerca volvulus Glucosylceramidase homolog 0.0146 0.0084 0.0843
Echinococcus granulosus laminin 0.0029 0.0005 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.098 0.0648 0.1143
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0029 0.0005 0.0029
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0001 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0265 0.0165 0.0164
Trypanosoma cruzi cytochrome P450, putative 0.0107 0.0058 0.2834
Echinococcus multilocularis neuropeptides capa receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis Niemann Pick C1 protein 0.0131 0.0074 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0217 0.0132 0.0727
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.1252 0.0832 0.1716
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0034 0.0009 0.0266
Schistosoma mansoni hypothetical protein 0.185 0.1235 0.2182
Echinococcus granulosus serotonin receptor 0.0217 0.0132 0.0131
Onchocerca volvulus 0.0028 0.0005 0.0039
Trichomonas vaginalis tubulin, putative 0.0077 0.0037 0.0375
Echinococcus multilocularis lamin dm0 0.0115 0.0063 0.0062
Echinococcus multilocularis FTZ F1 alpha 0.098 0.0648 0.0647
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0002 0.0001
Loa Loa (eye worm) tubulin alpha chain 0.0181 0.0108 0.0591
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0029 0.0005 0.0243
Echinococcus multilocularis serotonin receptor 0.0303 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0085 0.0043 0.0237
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0545 0.0354 0.0353
Brugia malayi MH2 domain containing protein 0.0567 0.0369 0.2024
Trichomonas vaginalis tubulin beta chain, putative 0.0181 0.0108 0.1088
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0034 0.0009 0.0048
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0457 0.0294 0.2973
Loa Loa (eye worm) hypothetical protein 0.0426 0.0273 0.1501
Loa Loa (eye worm) pyruvate kinase 0.0088 0.0045 0.0246
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.005 0.0019 0.0018
Schistosoma mansoni rab6-interacting 0.0028 0.0005 0.0006
Trichomonas vaginalis mannose-1-phosphate guanyltransferase, putative 0.0034 0.0009 0.0086
Loa Loa (eye worm) hypothetical protein 0.0523 0.0339 0.1862
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.098 0.0648 0.3557
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0034 0.0009 0.0514
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0322 0.0203 0.1117
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.053 0.0343 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0159 0.0093 0.0188
Brugia malayi larval opioid receptor 0.0217 0.0132 0.0727
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0027 0.0003 0.0019
Brugia malayi MH2 domain containing protein 0.0039 0.0012 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0039 0.0012 0.0064
Leishmania major hypothetical protein, conserved 0.005 0.0019 0.0547
Brugia malayi MH1 domain containing protein 0.0039 0.0012 0.0064
Echinococcus multilocularis GPCR, family 2 0.0402 0.0257 0.0256
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0004 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0019 0.0921
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0029 0.0005 0.0243
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Trichomonas vaginalis tubulin beta chain, putative 0.0181 0.0108 0.1088
Onchocerca volvulus 0.0113 0.0062 0.062
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 1.482 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0005 0.0007
Giardia lamblia Epsilon tubulin 0.0059 0.0025 0.0905
Onchocerca volvulus 0.0457 0.0294 0.2973
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0108 0.0058 0.0589
Echinococcus multilocularis pyruvate kinase 0.0045 0.0016 0.0015
Loa Loa (eye worm) TAR-binding protein 0.0105 0.0057 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Loa Loa (eye worm) tubulin beta chain 0.0265 0.0165 0.0904
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0092 0.0048 0.0261
Entamoeba histolytica hypothetical protein 0.0124 0.0069 0.4194
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0426 0.0273 0.0481
Brugia malayi Smad1 0.0039 0.0012 0.0064
Brugia malayi hypothetical protein 0.0028 0.0005 0.0025
Echinococcus granulosus Niemann Pick C1 protein 0.0092 0.0048 0.0046
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Schistosoma mansoni DNA polymerase eta 0.0051 0.002 0.0033
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0068 0.0031 0.0061
Brugia malayi Calcitonin receptor-like protein seb-1 0.1271 0.0844 0.4636
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0009 0.0086
Trichomonas vaginalis tubulin beta chain, putative 0.0181 0.0108 0.1088
Onchocerca volvulus 0.0217 0.0132 0.1334
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Plasmodium vivax importin-beta 2, putative 0.0027 0.0004 0.0116
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0029 0.0005 0.0145
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.005 0.0019 0.0018
Trypanosoma cruzi zeta tubulin, putative 0.0059 0.0025 0.1226
Mycobacterium ulcerans aldehyde dehydrogenase 0.053 0.0343 0.0706
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0056 0.0024 0.004
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0068 0.0031 0.1521
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus sterol regulatory element binding protein 0.0039 0.0012 0.0011
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.008 0.004 0.0398
Loa Loa (eye worm) hypothetical protein 0.0036 0.001 0.0055
Giardia lamblia hypothetical protein 0.005 0.0019 0.0665
Onchocerca volvulus 0.0045 0.0016 0.0156
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0068 0.0031 0.0061
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0457 0.0294 0.1616
Loa Loa (eye worm) hypothetical protein 0.2716 0.1821 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0068 0.0031 0.0061
Echinococcus granulosus FTZ F1 alpha 0.098 0.0648 0.0647
Echinococcus multilocularis isocitrate dehydrogenase 0.015 0.0087 0.0086
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.015 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Leishmania major cAMP-specific phosphodiesterase, putative 0.005 0.0019 0.0547
Trypanosoma brucei PAB1-binding protein , putative 0.0069 0.0033 0.1515
Trichomonas vaginalis tubulin gamma chain, putative 0.0135 0.0077 0.0777
Echinococcus multilocularis gamma secretase subunit aph 1 0.0831 0.0547 0.0546
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0009 0.034
Mycobacterium ulcerans pyruvate kinase 0.0088 0.0045 0.0089
Mycobacterium leprae POSSIBLE TRANSFERASE 0.0034 0.0009 0.0013
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0068 0.0031 0.0061
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Chlamydia trachomatis pyruvate kinase 0.0088 0.0045 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0009 0.0086
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus multilocularis tubulin gamma 1 chain 0.0135 0.0077 0.0076
Echinococcus granulosus tar DNA binding protein 0.0105 0.0057 0.0055
Echinococcus multilocularis dna polymerase kappa 0.0051 0.002 0.0019
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0068 0.0031 0.0061
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0056 0.0024 0.1419
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.018 0.0107 0.0106
Schistosoma mansoni alpha tubulin 0.0181 0.0108 0.0188
Echinococcus multilocularis neuropeptide FF receptor 2 0.0217 0.0132 0.0131
Brugia malayi ORL1-like opioid receptor 0.0217 0.0132 0.0727
Brugia malayi hypothetical protein 0.0023 0.0001 0.0008
Plasmodium falciparum cGMP-specific phosphodiesterase 0.005 0.0019 0.1058
Brugia malayi beta-lactamase 0.0113 0.0062 0.034
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.098 0.0648 0.3557
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0107 0.0058 0.0116
Brugia malayi Melatonin receptor type 1A 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0028 0.0004 0.0042
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0158 0.0092 0.0091
Echinococcus multilocularis tubulin alpha chain 0.0181 0.0108 0.0107
Trichomonas vaginalis glucosylceramidase, putative 0.0222 0.0136 0.1369
Brugia malayi Dopamine receptor 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0016
Brugia malayi G protein-coupled receptor F59B2.13 0.0217 0.0132 0.0727
Trypanosoma cruzi beta tubulin, putative 0.0265 0.0165 0.806
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0002 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0076
Brugia malayi Dopamine receptor protein 2 0.0217 0.0132 0.0727
Onchocerca volvulus Arrow homolog 0.0026 0.0003 0.0023
Onchocerca volvulus 0.0038 0.0011 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0062 0.3021
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0068 0.0032 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0044 0.0015 0.0083
Echinococcus granulosus tubulin alpha 1C chain 0.0181 0.0108 0.0107
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0034 0.0009 0.0514
Entamoeba histolytica serine acetyltransferase 1 0.0034 0.0009 0.0514
Giardia lamblia Alcohol dehydrogenase 0.0029 0.0005 0.0132
Loa Loa (eye worm) tubulin beta-2A chain 0.0265 0.0165 0.0904
Schistosoma mansoni pyruvate kinase 0.0088 0.0045 0.0077
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0034 0.0009 0.0086
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0029 0.0005 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.098 0.0648 0.0647
Brugia malayi mbt repeat family protein 0.0038 0.0011 0.0063
Mycobacterium tuberculosis Possible transferase 0.0034 0.0009 0.0014
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0034 0.0008 0.0399
Onchocerca volvulus 0.0025 0.0002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Brugia malayi follicle stimulating hormone receptor 0.0348 0.0221 0.1211
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0005 0.0007
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0029 0.0005 0.0007
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0039 0.0012 0.0067
Echinococcus multilocularis pyruvate kinase 0.0088 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0039 0.0012 0.0067
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0068 0.0031 0.0061
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Loa Loa (eye worm) G-protein coupled receptor 0.0217 0.0132 0.0727
Brugia malayi Niemann-Pick C1 protein precursor 0.0092 0.0048 0.0261
Mycobacterium ulcerans DNA polymerase IV 0.0051 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0115 0.0063 0.0348
Echinococcus granulosus G protein coupled receptor 139 0.0217 0.0132 0.0131
Trypanosoma brucei trypanothione reductase 0.007 0.0033 0.1517
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0013 0.0634
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.098 0.0648 0.0647
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0002 0.0001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Schistosoma mansoni retinoic acid receptor RXR 0.098 0.0648 0.1143
Schistosoma mansoni amine GPCR 0.0217 0.0132 0.0232
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0029 0.0005 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0217 0.0132 0.0232
Brugia malayi steroid hormone receptor 0.1186 0.0787 0.4323
Brugia malayi Serotonin receptor 0.0542 0.0351 0.193
Entamoeba histolytica tubulin family protein 0.0265 0.0165 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0076
Onchocerca volvulus 0.0023 0.0001 0.0007
Echinococcus granulosus pyruvate kinase 0.0045 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Echinococcus granulosus tubulin epsilon chain 0.0135 0.0077 0.0076
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.0062 0.0124
Schistosoma mansoni hypothetical protein 0.0038 0.0011 0.0018
Mycobacterium ulcerans cell division protein FtsZ 0.0059 0.0025 0.0048
Echinococcus multilocularis polycomb protein SCMH1 0.0038 0.0011 0.001
Schistosoma mansoni lipoxygenase 0.0079 0.0039 0.0067
Loa Loa (eye worm) tubulin alpha-3 chain 0.0104 0.0056 0.0307
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0008
Loa Loa (eye worm) intermediate filament protein 0.0115 0.0063 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Schistosoma mansoni smad1 5 8 and 0.0039 0.0012 0.0019
Loa Loa (eye worm) hypothetical protein 0.0523 0.0339 0.1862
Echinococcus granulosus pyruvate kinase 0.0045 0.0016 0.0015
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0009 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0009 0.0086
Echinococcus granulosus 7tm_1 domain containing protein 0.0217 0.0132 0.0131
Schistosoma mansoni gdp-mannose pyrophosphorylase b isoform 2 0.0035 0.0009 0.0015
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0028 0.0004 0.0122
Leishmania major trypanothione reductase 0.007 0.0033 0.094
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1303 0.0866 0.4757
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0029 0.0005 0.0037
Echinococcus multilocularis tubulin alpha chain 0.0181 0.0108 0.0107
Echinococcus multilocularis histone acetyltransferase MYST2 0.0044 0.0015 0.0014
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0108 0.0058 0.0321
Schistosoma mansoni hypothetical protein 0.0402 0.0257 0.0453
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0039 0.0012 0.0019
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0071 0.0033 0.0065
Brugia malayi Dopamine receptor protein 1 0.0217 0.0132 0.0727
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Mycobacterium leprae PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) 0.0034 0.0009 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0047
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0068 0.0032 0.1532
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.005 0.0019 0.0018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.098 0.0648 0.1143
Mycobacterium tuberculosis Probable reductase 0.0159 0.0093 0.0188
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.0062 0.0624
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.1252 0.0832 0.9098
Echinococcus granulosus Niemann Pick C1 protein 0.0131 0.0074 0.0073
Trichomonas vaginalis tubulin alpha chain, putative 0.0135 0.0077 0.0777
Echinococcus granulosus chromobox protein 1 0.0051 0.002 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus granulosus lamin 0.0115 0.0063 0.0062
Brugia malayi GnHR receptor homolog 0.0217 0.0132 0.0727
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0189 0.0113 0.0112
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0217 0.0132 0.0232
Loa Loa (eye worm) MBCTL1 0.0044 0.0015 0.0083
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.015 0.0087 0.0176
Echinococcus granulosus nuclear factor of activated T cells 5 0.0041 0.0013 0.0012
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0014 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-31 0.098 0.0648 0.3557
Schistosoma mansoni survival motor neuron protein 0.0045 0.0016 0.0026
Plasmodium falciparum alpha tubulin 1 0.0181 0.0108 0.65
Loa Loa (eye worm) CXXC zinc finger family protein 0.0115 0.0063 0.0346
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0358 0.0227 0.1248
Echinococcus granulosus g-protein coupled receptor 0.0217 0.0132 0.0131
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0089 0.0046 0.025
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0056 0.0024 0.0022
Echinococcus granulosus peptide allatostatin:somatostatin 0.0217 0.0132 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0202 0.0122 0.0213
Plasmodium falciparum LCCL domain-containing protein 0.0028 0.0005 0.0171
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0545 0.0354 0.0353
Trypanosoma cruzi Aph-1 protein, putative 0.0324 0.0204 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0071 0.0033 0.0345
Mycobacterium ulcerans DNA polymerase IV 0.0051 0.002 0.0037
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.0062 0.0124
Echinococcus granulosus Tubulin beta 2C chain 0.0265 0.0165 0.0164
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.005 0.0019 0.0018
Leishmania major zeta tubulin, putative 0.0059 0.0025 0.0729
Echinococcus granulosus Tubulin beta 2C chain 0.0265 0.0165 0.0164
Loa Loa (eye worm) hypothetical protein 0.0061 0.0027 0.0148
Schistosoma mansoni hypothetical protein 0.185 0.1235 0.2182
Plasmodium vivax tubulin gamma chain, putative 0.0135 0.0077 0.4619
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0026 0.0003 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0722 0.0473 0.0975
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0457 0.0294 0.0293
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0009 0.034
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0029 0.0005 0.0007
Schistosoma mansoni pyruvate kinase 0.0088 0.0045 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Onchocerca volvulus 0.1483 0.0988 1
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0028 0.0004 0.013
Trypanosoma brucei Aph-1 protein, putative 0.0324 0.0204 1
Schistosoma mansoni hypothetical protein 0.0217 0.0132 0.0232
Trypanosoma brucei epsilon tubulin 0.0135 0.0077 0.3716
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0523 0.0339 0.1862
Entamoeba histolytica tubulin gamma chain 0.0135 0.0077 0.467
Schistosoma mansoni hypothetical protein 0.0038 0.0011 0.0018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0217 0.0132 0.0131
Brugia malayi hypothetical protein 0.1212 0.0805 0.4419
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0105
Echinococcus multilocularis snurportin 1 0.0287 0.0179 0.0178
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.005 0.0019 0.0921
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0002 0.0016
Echinococcus granulosus Protein patched homolog 1 0.0039 0.0012 0.0011
Brugia malayi PHD-finger family protein 0.0025 0.0002 0.0013
Echinococcus granulosus neuropeptide Y receptor 0.0217 0.0132 0.0131
Schistosoma mansoni inositol monophosphatase 0.0041 0.0013 0.0021
Entamoeba histolytica tubulin family protein 0.0265 0.0165 1
Trypanosoma brucei alpha tubulin 0.0181 0.0108 0.523
Trypanosoma cruzi tubulin delta chain 0.0059 0.0025 0.1226
Schistosoma mansoni thyroid hormone receptor 0.098 0.0648 0.1143
Schistosoma mansoni hypothetical protein 0.0402 0.0257 0.0453
Loa Loa (eye worm) hypothetical protein 0.0051 0.002 0.011
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Toxoplasma gondii eukaryotic initiation factor-2B, epsilon subunit, putative 0.0034 0.0009 0.0076
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0039 0.0012 0.0011
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0545 0.0354 0.1945
Loa Loa (eye worm) aldehyde dehydrogenase 0.0029 0.0005 0.0029
Entamoeba histolytica tubulin alpha-1 chain 0.0181 0.0108 0.6533
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0055 0.0023 0.1096
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.015 0.0087 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0019 0.019
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0055 0.0023 0.0021
Leishmania major aldehyde dehydrogenase, putative 0.0029 0.0005 0.0145
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0028 0.0004 0.0025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.015 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0068 0.0031 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0009 0.0014
Brugia malayi aldehyde dehydrogenase 0.0029 0.0005 0.0029
Echinococcus multilocularis chromobox protein 1 0.0051 0.002 0.0019
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0029 0.0005 0.0145
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0068 0.0032 0.1532
Loa Loa (eye worm) G protein alpha subunit 3 0.0023 0.0001 0.0008
Leishmania major aldehyde dehydrogenase, putative 0.0029 0.0005 0.0145
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.098 0.0648 0.0647
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0034 0.0009 0.0048
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0079 0.0039 0.0067
Loa Loa (eye worm) hypothetical protein 0.0024 0.0002 0.0011
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.1058
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0029 0.0005 0.0007
Mycobacterium ulcerans hypothetical protein 0.1252 0.0832 0.1716
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.005 0.0019 0.0018
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0028 0.0004 0.0205
Brugia malayi AKH receptor 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus neuropeptide receptor A26 0.2734 0.1833 0.1832
Schistosoma mansoni neuropeptide F-like receptor 0.0217 0.0132 0.0232
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.002 0.0965
Brugia malayi Nuclear hormone receptor family member nhr-3 0.098 0.0648 0.3557
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0055 0.0023 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-40 0.098 0.0648 0.3557
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Brugia malayi nuclear receptor NHR-67 0.0457 0.0294 0.1616
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Echinococcus granulosus retinoic acid receptor rxr beta a 0.098 0.0648 0.0647
Brugia malayi Cytochrome P450 family protein 0.0068 0.0031 0.0172
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0457 0.0294 0.1616
Loa Loa (eye worm) hypothetical protein 0.0052 0.0021 0.0113
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0008
Loa Loa (eye worm) beta-lactamase 0.0113 0.0062 0.034
Brugia malayi RNA recognition motif domain containing protein 0.0105 0.0057 0.0311
Loa Loa (eye worm) hypothetical protein 0.0523 0.0339 0.1862
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0009 0.0086
Trichomonas vaginalis chromobox protein, putative 0.0051 0.002 0.0201
Brugia malayi Steroid receptor seven-up type 2 0.098 0.0648 0.3557
Loa Loa (eye worm) melatonin receptor type 1A 0.0217 0.0132 0.0727
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.005 0.0019 0.0105
Loa Loa (eye worm) DR-78 0.0457 0.0294 0.1616
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.005 0.0019 0.0018
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.005 0.0019 0.0018
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0108 0.0058 0.3479
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0545 0.0354 0.0353
Loa Loa (eye worm) dynactin 5 0.0034 0.0009 0.0048
Brugia malayi MAP kinase sur-1 0.0068 0.0032 0.0173
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.002 0.0202
Toxoplasma gondii thioredoxin reductase 0.007 0.0033 0.0337
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Brugia malayi Nuclear hormone receptor-like 1 0.098 0.0648 0.3557
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.005 0.0019 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0014
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0029 0.0005 0.0243
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0217 0.0132 0.0131
Brugia malayi G-protein alpha subunit 0.0023 0.0001 0.0008
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0407 0.0261 0.1432
Entamoeba histolytica acetyltransferase, putative 0.0034 0.0009 0.0514
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus multilocularis microtubule associated protein 2 0.1715 0.1144 0.1143
Schistosoma mansoni smad 0.0039 0.0012 0.0019
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0358 0.0227 0.1248
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.005 0.0019 0.0032
Trypanosoma brucei epsilon tubulin 0.0135 0.0077 0.3716
Brugia malayi Pyruvate kinase, M2 isozyme 0.0088 0.0045 0.0246
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0068 0.0031 0.0061
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus multilocularis expressed conserved protein 0.0086 0.0044 0.0043
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0023 0.0001 0.0008
Brugia malayi nuclear hormone receptor family member nhr-6 0.0457 0.0294 0.1616
Plasmodium vivax SET domain protein, putative 0.0189 0.0113 0.6847
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0034 0.0008 0.0399
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0009 0.0008
Echinococcus multilocularis beta tubulin 0.0265 0.0165 0.0164
Plasmodium falciparum dynactin subunit 5, putative 0.0034 0.0009 0.0423
Echinococcus multilocularis somatostatin receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0077 0.0037 0.0375
Echinococcus multilocularis thioredoxin glutathione reductase 0.007 0.0033 0.0031
Schistosoma mansoni amine GPCR 0.0217 0.0132 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0071 0.0033 0.7321
Echinococcus multilocularis thyroid hormone receptor alpha 0.098 0.0648 0.0647
Entamoeba histolytica G protein alpha subunit, putative 0.0023 0.0001 0.0067
Loa Loa (eye worm) RNA binding protein 0.0105 0.0057 0.0311
Schistosoma mansoni hypothetical protein 0.0038 0.0011 0.0018
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Brugia malayi tubulin alpha chain - mouse 0.0181 0.0108 0.0591
Trypanosoma brucei DNA polymerase IV, putative 0.0051 0.002 0.0896
Toxoplasma gondii beta tubulin 0.0265 0.0165 0.1786
Mycobacterium ulcerans transferase 0.0034 0.0009 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Schistosoma mansoni nuclear hormone receptor 0.0457 0.0294 0.0518
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Echinococcus multilocularis Tolloid protein 1 0.0089 0.0046 0.0044
Schistosoma mansoni tubulin subunit gamma 0.0135 0.0077 0.0134
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.002 0.011
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.098 0.0648 0.0647
Echinococcus multilocularis fmrfamide receptor 0.0217 0.0132 0.0131
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Echinococcus granulosus biogenic amine 5HT receptor 0.0483 0.0312 0.0311
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Leishmania major phosphopantetheinyl transferase-like protein 0.0071 0.0033 0.0962
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0068 0.0031 0.0061
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0068 0.0031 0.1456
Echinococcus multilocularis muscleblind protein 1 0.0267 0.0166 0.0165
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0013 0.0377
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0159 0.0093 0.0188
Echinococcus granulosus pyruvate kinase 0.0088 0.0045 0.0044
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0029 0.0005 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0033 0.1554
Plasmodium vivax ataxin-2 like protein, putative 0.0069 0.0033 0.1883
Brugia malayi Nuclear hormone receptor family member nhr-19 0.098 0.0648 0.3557
Onchocerca volvulus 0.0217 0.0132 0.1334
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0002 0.0001
Toxoplasma gondii pyruvate kinase PyKII 0.0045 0.0016 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.098 0.0648 0.3557
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.0032 0.1532
Echinococcus granulosus expressed conserved protein 0.0086 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Plasmodium vivax tubulin beta chain, putative 0.0265 0.0165 1
Loa Loa (eye worm) pyruvate kinase 0.0088 0.0045 0.0246
Brugia malayi tailless protein 0.0457 0.0294 0.1616
Mycobacterium tuberculosis Conserved hypothetical protein 0.1252 0.0832 0.1716
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.0062 0.0061
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0068 0.0031 0.1521
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0217 0.0132 0.0232
Entamoeba histolytica hypothetical protein 0.0071 0.0033 0.2008
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0358 0.0227 0.0226
Schistosoma mansoni chromobox protein 0.0051 0.002 0.0034
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Schistosoma mansoni tubulin subunit alpha 0.0181 0.0108 0.0188
Leishmania major cytochrome p450-like protein 0.0068 0.0031 0.0904
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0071 0.0033 0.0065
Leishmania major pyruvate kinase 0.0088 0.0045 0.1298
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0407 0.0261 0.026
Echinococcus multilocularis ecdysone induced protein 78C 0.098 0.0648 0.0647
Plasmodium falciparum tubulin gamma chain 0.0135 0.0077 0.4619
Entamoeba histolytica pyruvate kinase, putative 0.0061 0.0027 0.1618
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0457 0.0294 0.2973
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0241 0.0148 0.7253
Onchocerca volvulus Pyruvate kinase homolog 0.0088 0.0045 0.0447
Schistosoma mansoni cpg binding protein 0.0115 0.0063 0.0109
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Echinococcus granulosus pyruvate kinase 0.0088 0.0045 0.0044
Plasmodium falciparum ataxin-2 like protein, putative 0.0069 0.0033 0.1883
Loa Loa (eye worm) glutathione reductase 0.007 0.0033 0.0179
Loa Loa (eye worm) AStacin protease 0.0056 0.0023 0.0127
Trypanosoma brucei cytochrome P450, putative 0.0107 0.0058 0.2779
Brugia malayi Cell division protein ftsZ 0.0059 0.0025 0.0139
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0176 0.0105 0.0211
Echinococcus multilocularis mannose 1 phosphate guanyltransferase 0.0035 0.0009 0.0008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0056 0.0023 0.0022
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Brugia malayi hypothetical protein 0.0457 0.0294 0.1616
Giardia lamblia Pyruvate kinase 0.0045 0.0016 0.0546
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0056 0.0024 0.013
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0023 0.0001 0.0008
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.005 0.0019 0.0105
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0028 0.0004 0.013
Mycobacterium tuberculosis Cell division protein FtsZ 0.0059 0.0025 0.0048
Giardia lamblia Pyruvate kinase 0.0088 0.0045 0.1659
Echinococcus granulosus neuropeptide FF receptor 2 0.0217 0.0132 0.0131
Toxoplasma gondii hypothetical protein 0.0034 0.0009 0.0076
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0071 0.0033 0.1932
Loa Loa (eye worm) BEN-1 protein 0.0265 0.0165 0.0904
Trypanosoma brucei protein kinase, putative 0.0068 0.0032 0.1467
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0023 0.0001 0.0008
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.005 0.0019 0.0921
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0029 0.0005 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) Smad1 0.0039 0.0012 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Treponema pallidum exodeoxyribonuclease (exoA) 0.0034 0.0009 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0004 0.0205
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0029 0.0005 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.053 0.0343 0.0706
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0217 0.0132 0.0727
Echinococcus granulosus orexin receptor type 2 0.0217 0.0132 0.0131
Giardia lamblia Kinase, CMGC MAPK 0.0068 0.0032 0.1147
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0029 0.0005 0.0004
Leishmania major hypothetical protein, conserved 0.0113 0.0062 0.1795
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0009 0.0423
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0068 0.0031 0.0061
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.005 0.0019 0.019
Brugia malayi hypothetical protein 0.0457 0.0294 0.1616
Echinococcus granulosus tubulin subunit TubB 0.0181 0.0108 0.0107
Schistosoma mansoni hypothetical protein 0.0045 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0115 0.0063 0.0348
Schistosoma mansoni cpg binding protein 0.0122 0.0068 0.0119
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0217 0.0132 0.0131
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.098 0.0648 0.0647
Echinococcus granulosus nuclear receptor 2DBD gamma 0.098 0.0648 0.0647
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0029 0.0005 0.0007
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0034 0.0008 0.0326
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0041 0.0013 0.0012
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0056 0.0024 0.068
Entamoeba histolytica hypothetical protein 0.0124 0.0069 0.4194
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Echinococcus granulosus mixed lineage leukemia protein mll 0.0035 0.0009 0.0008
Brugia malayi putative neuropeptide receptor 0.0217 0.0132 0.0727
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Toxoplasma gondii ABC1 family protein 0.0113 0.0062 0.0659
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.098 0.0648 0.3557
Schistosoma mansoni importin beta-1 0.0027 0.0004 0.0005
Echinococcus granulosus ecdysone induced protein 78C 0.098 0.0648 0.0647
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0023 0.0001 0.0011
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.1058
Loa Loa (eye worm) inositol-1 0.0041 0.0013 0.0073
Schistosoma mansoni tubulin subunit beta 0.0265 0.0165 0.0289
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Brugia malayi zgc:92842 0.0034 0.0009 0.0048
Trypanosoma brucei zeta tubulin, putative 0.0059 0.0025 0.1158
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0029 0.0005 0.0007
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0108 0.0058 0.0101
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0002 0.0001
Schistosoma mansoni opsin-like receptor 0.0217 0.0132 0.0232
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0051 0.002 0.0019
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0105 0.0057 0.0311
Onchocerca volvulus 0.0217 0.0132 0.1334
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0008
Loa Loa (eye worm) thioredoxin reductase 0.007 0.0033 0.0179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0034 0.0009 0.0414
Schistosoma mansoni opsin-like receptor 0.0217 0.0132 0.0232
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0002 0.0001
Echinococcus multilocularis pyruvate kinase 0.0045 0.0016 0.0015
Echinococcus granulosus tubulin subunit beta 0.0265 0.0165 0.0164
Echinococcus granulosus histone acetyltransferase MYST2 0.0044 0.0015 0.0014
Echinococcus multilocularis tubulin alpha 3 chain 0.0181 0.0108 0.0107
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0004 0.0021
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0407 0.0261 0.0459
Loa Loa (eye worm) tubulin alpha 2 0.0045 0.0016 0.0089
Echinococcus granulosus beta tubulin 0.0265 0.0165 0.0164
Schistosoma mansoni Smad4 0.0039 0.0012 0.0019
Brugia malayi ecdysone receptor 0.0457 0.0294 0.1616
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0068 0.0031 0.0061
Trypanosoma brucei tubulin delta chain 0.0059 0.0025 0.1158
Schistosoma mansoni nuclear hormone receptor 0.0457 0.0294 0.0518
Mycobacterium ulcerans beta-lactamase 0.0113 0.0062 0.0124
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Plasmodium falciparum liver specific protein 2, putative 0.0034 0.0009 0.0423
Toxoplasma gondii isocitrate dehydrogenase 0.015 0.0087 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0051 0.002 0.0037
Mycobacterium tuberculosis Probable oxidoreductase 0.0176 0.0105 0.0213
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0217 0.0132 0.0727
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0028 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) cytochrome P450 family protein 0.0219 0.0133 0.0732
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0035 0.0009 0.0052
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Toxoplasma gondii aldehyde dehydrogenase 0.053 0.0343 0.3746
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0069 0.0033 0.0179
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0217 0.0132 0.0727
Entamoeba histolytica acetyltransferase, putative 0.0034 0.0009 0.0514
Leishmania major mitochondrial DNA polymerase beta 0.0241 0.0148 0.4311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0035 0.0009 0.0008
Brugia malayi Nucleotidyl transferase family protein 0.0035 0.0009 0.0052
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.098 0.0648 0.1143
Echinococcus multilocularis G protein coupled receptor 139 0.0217 0.0132 0.0131
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Echinococcus granulosus tubulin alpha chain 0.0181 0.0108 0.0107
Brugia malayi Muscleblind-like protein 0.0267 0.0166 0.0911
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0068 0.0031 0.0061
Trypanosoma brucei GDP-mannose pyrophosphorylase 0.0035 0.0009 0.0375
Echinococcus multilocularis neuropeptide receptor A26 0.2734 0.1833 0.1832
Loa Loa (eye worm) cytochrome P450 family protein 0.0107 0.0058 0.0319
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0029 0.0005 0.0243
Loa Loa (eye worm) hypothetical protein 0.0202 0.0122 0.0669
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0089 0.0901
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.0062 0.0124
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.005 0.0019 0.0018
Echinococcus granulosus dna polymerase kappa 0.0051 0.002 0.0019
Trichomonas vaginalis set domain proteins, putative 0.1483 0.0988 1
Echinococcus granulosus Tubulin beta 2C chain 0.0265 0.0165 0.0164
Trypanosoma cruzi pyruvate kinase 2, putative 0.0088 0.0045 0.2183
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0457 0.0294 0.0293
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0029 0.0005 0.0037
Echinococcus multilocularis laminin 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0108 0.0058 0.0321
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0002 0.0001
Echinococcus multilocularis Tubulin beta 2C chain 0.0265 0.0165 0.0164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0029 0.0005 0.0007
Trichomonas vaginalis tubulin epsilon chain, putative 0.0265 0.0165 0.1665
Trypanosoma brucei alpha tubulin 0.0181 0.0108 0.523
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0068 0.0031 0.0061
Schistosoma mansoni hypothetical protein 0.0217 0.0132 0.0232
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0068 0.0031 0.0061
Echinococcus multilocularis neuropeptide receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis RUN 0.0028 0.0005 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0076
Loa Loa (eye worm) BEN-1 protein 0.0265 0.0165 0.0904
Echinococcus multilocularis sterol regulatory element binding protein 0.0039 0.0012 0.0011
Onchocerca volvulus 0.0217 0.0132 0.1334
Trichomonas vaginalis tubulin gamma chain, putative 0.0135 0.0077 0.0777
Mycobacterium ulcerans hypothetical protein 0.1252 0.0832 0.1716
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0055 0.0023 0.0038
Onchocerca volvulus Huntingtin homolog 0.021 0.0128 0.1286
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.005 0.0019 0.0921
Leishmania major cytochrome p450-like protein 0.0068 0.0031 0.0904
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0159 0.0093 0.0187
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0044 0.0015 0.0014
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.015 0.0087 0.0151
Leishmania major serine acetyltransferase 0.0034 0.0009 0.0246
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0009 0.0086
Echinococcus granulosus Tubulin alpha 1 chain 0.0181 0.0108 0.0107
Leishmania major delta tubulin, putative 0.0059 0.0025 0.0729
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0005 0.0007
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0029 0.0005 0.0302
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0176 0.0105 0.0213
Echinococcus granulosus tubulin gamma 1 chain 0.0135 0.0077 0.0076
Echinococcus multilocularis dynactin 5 p25 0.0034 0.0009 0.0008
Loa Loa (eye worm) nuclear hormone receptor 0.0457 0.0294 0.1616
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis helicase, putative 0.0026 0.0003 0.0028
Loa Loa (eye worm) cytochrome P450 0.0068 0.0031 0.0172
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0358 0.0227 0.0226
Loa Loa (eye worm) alpha-tubulin 0.0181 0.0108 0.0591
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0003 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0062 0.0624
Trypanosoma brucei pyruvate kinase 1, putative 0.0088 0.0045 0.2123
Brugia malayi exodeoxyribonuclease III family protein 0.0034 0.0009 0.0048
Echinococcus granulosus tubulin delta chain 0.0059 0.0025 0.0024
Brugia malayi latrophilin 2 splice variant baaae 0.0869 0.0573 0.3144
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Echinococcus multilocularis tubulin alpha 0.0135 0.0077 0.0076
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.0032 0.1532
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0028 0.0004 0.0161
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0217 0.0132 0.0131
Brugia malayi Tachykinin-like peptides receptor 99D 0.0217 0.0132 0.0727
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Brugia malayi RNA, U transporter 1 0.0076 0.0037 0.0204
Trypanosoma cruzi hypothetical protein 0.0034 0.0009 0.0414
Brugia malayi Tubulin gamma chain 0.0135 0.0077 0.0423
Brugia malayi glutathione reductase 0.007 0.0033 0.0179
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.098 0.0648 0.3557
Plasmodium falciparum tubulin beta chain 0.0265 0.0165 1
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0005 0.0034
Schistosoma mansoni amine GPCR 0.0334 0.0211 0.0371
Echinococcus granulosus g protein coupled receptor 0.0217 0.0132 0.0131
Trichomonas vaginalis tubulin gamma chain, putative 0.0059 0.0025 0.0253
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0217 0.0132 0.0232
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0068 0.0031 0.1521
Schistosoma mansoni ap endonuclease 0.0034 0.0009 0.0013
Mycobacterium ulcerans serine acetyltransferase CysE 0.0034 0.0009 0.0014
Trypanosoma brucei alpha tubulin 0.0181 0.0108 0.523
Schistosoma mansoni inositol monophosphatase 0.0041 0.0013 0.0021
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0071 0.0033 0.0379
Schistosoma mansoni hypothetical protein 0.0029 0.0005 0.0007
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus granulosus TGF beta signal transducer SmadC 0.0039 0.0012 0.0011
Schistosoma mansoni tubulin subunit beta 0.0265 0.0165 0.0289
Plasmodium vivax pyruvate kinase 2, putative 0.0045 0.0016 0.0868
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0068 0.0031 0.0061
Echinococcus granulosus g protein coupled receptor 0.0217 0.0132 0.0131
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0029 0.0005 0.0007
Trichomonas vaginalis DNA polymerase eta, putative 0.0051 0.002 0.0199
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Brugia malayi hypothetical protein 0.0222 0.0135 0.0743
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0029 0.0005 0.0007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0056 0.0023 0.0022
Entamoeba histolytica serine acetyltransferase 1 0.0034 0.0009 0.0514
Loa Loa (eye worm) hypothetical protein 0.0402 0.0257 0.1413
Echinococcus multilocularis lipoxygenase domain containing protein 0.0028 0.0005 0.0003
Entamoeba histolytica ankyrin, putative 0.0034 0.0009 0.0516
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.1058
Schistosoma mansoni tubulin subunit epsilon 0.0135 0.0077 0.0134
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0217 0.0132 0.0131
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0029 0.0005 0.0168
Brugia malayi neuropeptide F receptor 0.0217 0.0132 0.0727
Trypanosoma brucei pyruvate kinase 1 0.0088 0.0045 0.2123
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Schistosoma mansoni tubulin subunit alpha 0.0059 0.0025 0.0043
Echinococcus multilocularis tubulin beta 1 chain 0.0265 0.0165 0.0164
Echinococcus multilocularis g-protein coupled receptor 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0303 0.019 0.1046
Giardia lamblia Beta tubulin 0.0265 0.0165 0.6288
Loa Loa (eye worm) mbt repeat family protein 0.0038 0.0011 0.0063
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.015 0.0087 0.4244
Trichomonas vaginalis tubulin beta chain, putative 0.0181 0.0108 0.1088
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0068 0.0031 0.0061
Trichomonas vaginalis tubulin epsilon chain, putative 0.0181 0.0108 0.1088
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0068 0.0031 0.0061
Echinococcus multilocularis tubulin alpha chain 0.0181 0.0108 0.0107
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus multilocularis tubulin delta chain 0.0059 0.0025 0.0024
Loa Loa (eye worm) neuropeptide F receptor 0.0217 0.0132 0.0727
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0068 0.0032 0.0326
Plasmodium vivax tubulin alpha chain, putative 0.0181 0.0108 0.65
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0055 0.0023 0.0803
Onchocerca volvulus 0.0217 0.0132 0.1334
Echinococcus multilocularis 0.0068 0.0031 0.003
Echinococcus granulosus beta tubulin 0.0265 0.0165 0.0164
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0006 0.0062
Toxoplasma gondii pyruvate kinase PyK1 0.0088 0.0045 0.0471
Loa Loa (eye worm) hypothetical protein 0.0523 0.0339 0.1862
Echinococcus multilocularis protein dispatched 1 0.0045 0.0016 0.0015
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.0011 0.0018
Mycobacterium tuberculosis Conserved hypothetical protein 0.0127 0.0071 0.0143
Trichomonas vaginalis chromobox protein, putative 0.0051 0.002 0.0201
Echinococcus granulosus nuclear receptor nhr 48 0.0457 0.0294 0.0293
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.002 0.0037
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0217 0.0132 0.0232
Echinococcus granulosus cytochrome P450 2K1 0.0068 0.0031 0.003
Onchocerca volvulus 0.0023 0.0001 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0068 0.0031 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0032 0.0316
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Brugia malayi Nuclear hormone receptor family member nhr-41 0.098 0.0648 0.3557
Brugia malayi Pre-SET motif family protein 0.1303 0.0866 0.4757
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.005 0.0019 0.019
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.001 0.0018
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0029 0.0005 0.0007
Trichomonas vaginalis tubulin, putative 0.0059 0.0025 0.0253
Loa Loa (eye worm) tubulin alpha 2 0.0122 0.0068 0.0373
Leishmania major hypothetical protein, conserved 0.0034 0.0009 0.0246
Brugia malayi Tubulin alpha-2 chain 0.0181 0.0108 0.0591
Brugia malayi Tubulin beta chain 0.0077 0.0037 0.0205
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0028 0.0004 0.0003
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0068 0.0032 0.0911
Brugia malayi Doublecortin family protein 0.0028 0.0005 0.0025
Giardia lamblia Translation initiation factor 0.0034 0.0009 0.0266
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0059 0.0025 0.0257
Plasmodium vivax tubulin epsilon chain, putative 0.0135 0.0077 0.4619
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0034 0.0009 0.0008
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0251 0.0155 0.0272
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Trypanosoma brucei beta tubulin 0.0265 0.0165 0.8046
Entamoeba histolytica acetyltransferase, putative 0.0034 0.0009 0.0514
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0029 0.0005 0.0029
Schistosoma mansoni smad1 5 8 and 0.0039 0.0012 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Loa Loa (eye worm) G-protein coupled receptor 0.0217 0.0132 0.0727
Echinococcus granulosus pyruvate kinase 0.0045 0.0016 0.0015
Echinococcus granulosus histone lysine methyltransferase setb 0.0202 0.0122 0.0121
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.005 0.0019 0.0105
Onchocerca volvulus Protein ultraspiracle homolog 0.098 0.0648 0.6554
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0005 0.0027
Loa Loa (eye worm) tubulin alpha-2 chain 0.0181 0.0108 0.0591
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0217 0.0132 0.0232
Trypanosoma cruzi serine acetyltransferase, putative 0.0034 0.0009 0.0414
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0029 0.0005 0.0007
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0108 0.0058 0.0057
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0004 0.0003
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0023 0.0001 0.0008
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0009 0.0423
Echinococcus granulosus L aminoadipate semialdehyde 0.0251 0.0155 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0028 0.0004 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0217 0.0132 0.0727
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0029 0.0005 0.0168
Loa Loa (eye worm) hypothetical protein 0.0267 0.0166 0.0911
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0019 0.0921
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0023 0.0001 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0009 0.0414
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.0011 0.0018
Brugia malayi hypothetical protein 0.0034 0.0009 0.0048
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0051 0.002 0.0019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.098 0.0648 0.6554
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0029 0.0005 0.0004
Echinococcus granulosus Tolloid protein 1 0.0089 0.0046 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0068 0.0031 0.0061
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0028 0.0004 0.0205
Mycobacterium tuberculosis Conserved protein 0.0113 0.0062 0.0124
Mycobacterium leprae Probable pyruvate kinase PykA 0.0088 0.0045 0.0088
Trypanosoma brucei beta tubulin 0.0265 0.0165 0.8046
Onchocerca volvulus 0.098 0.0648 0.6554
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0457 0.0294 0.0293
Schistosoma mansoni biogenic amine receptor 0.0217 0.0132 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0025 0.0253
Brugia malayi Nuclear hormone receptor E75 0.0457 0.0294 0.1616
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0055 0.0023 0.0124
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.0062 0.0124
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Schistosoma mansoni tar DNA-binding protein 0.0105 0.0057 0.0098
Trypanosoma brucei unspecified product 0.0035 0.0009 0.0368
Echinococcus granulosus microtubule associated protein 2 0.1715 0.1144 0.1143
Schistosoma mansoni rab6-interacting 0.0028 0.0005 0.0006
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0023 0.0001 0.0011
Echinococcus granulosus muscleblind protein 0.0267 0.0166 0.0165
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0068 0.0031 0.0061
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0002 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis Tubulin beta 2C chain 0.0265 0.0165 0.0164
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0089 0.0046 0.0079
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0034 0.0009 0.0008
Plasmodium falciparum tubulin epsilon chain, putative 0.0135 0.0077 0.4619
Trypanosoma brucei nucleotidyl transferase, putative 0.0035 0.0009 0.0375
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0068 0.0031 0.0061
Echinococcus granulosus mitogen activated protein kinase 3 0.0068 0.0032 0.003
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0029 0.0005 0.0007
Echinococcus granulosus peroxisome assembly protein 26 0.0181 0.0108 0.0107
Brugia malayi F/Y-rich N-terminus family protein 0.0043 0.0015 0.0081
Loa Loa (eye worm) tubulin alpha chain 0.0181 0.0108 0.0591
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0029 0.0005 0.0004
Brugia malayi CHE-14 protein 0.0039 0.0012 0.0067
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0348 0.0221 0.1211
Loa Loa (eye worm) hypothetical protein 0.0056 0.0023 0.0127
Mycobacterium ulcerans d-alpha-D-mannose-1-phosphate guanylyltransferase ManB 0.0035 0.0009 0.0016
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0002 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0023 0.0226
Echinococcus granulosus neuropeptides capa receptor 0.0217 0.0132 0.0131
Echinococcus multilocularis SAM and MBT domain containing protein 0.0038 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Echinococcus multilocularis orexin receptor type 2 0.0217 0.0132 0.0131
Loa Loa (eye worm) cytochrome P450 family protein 0.0107 0.0058 0.0319
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0089 0.0901
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0006 0.0062
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0023 0.0001 0.0008
Trichomonas vaginalis tubulin gamma chain, putative 0.0265 0.0165 0.1665
Toxoplasma gondii beta-tubulin, putative 0.0265 0.0165 0.1786
Echinococcus granulosus smad 0.0039 0.0012 0.0011
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0055 0.0023 0.0021
Brugia malayi RNA binding protein 0.0105 0.0057 0.0311
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0002 0.0132
Loa Loa (eye worm) hypothetical protein 0.0053 0.0022 0.0119
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0034 0.0009 0.0008
Onchocerca volvulus Huntingtin homolog 0.021 0.0128 0.1286
Trichomonas vaginalis tubulin, putative 0.0265 0.0165 0.1665
Brugia malayi nuclear receptor NHR-88 0.0457 0.0294 0.1616
Schistosoma mansoni zinc finger protein 0.0457 0.0294 0.0518
Echinococcus multilocularis Tubulin alpha 1 chain 0.0181 0.0108 0.0107
Brugia malayi orphan nuclear receptor NR2E1 0.0457 0.0294 0.1616
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0831 0.0547 0.3003
Echinococcus granulosus intermediate filament protein 0.0115 0.0063 0.0062
Brugia malayi hypothetical protein 0.021 0.0128 0.0701
Echinococcus granulosus dna polymerase eta 0.0051 0.002 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Schistosoma mansoni nuclear hormone receptor 0.098 0.0648 0.1143
Brugia malayi G-protein coupled receptor 0.0217 0.0132 0.0727
Schistosoma mansoni aldehyde dehydrogenase 0.053 0.0343 0.0605
Giardia lamblia Rab geranylgeranyltransferase 0.0028 0.0004 0.0101
Mycobacterium ulcerans hypothetical protein 0.0127 0.0071 0.0143
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0029 0.0005 0.0243
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0545 0.0354 0.0353
Brugia malayi Fibulin-1 precursor 0.0029 0.0005 0.0027
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0407 0.0261 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.6227 0.4193 0.4193
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.005 0.0019 0.0032
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.015 0.0087 0.4244
Brugia malayi hypothetical protein 0.0523 0.0339 0.1862
Plasmodium vivax multidomain scavenger receptor, putative 0.0028 0.0005 0.0171
Trichomonas vaginalis tubulin alpha chain, putative 0.0265 0.0165 0.1665
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Echinococcus granulosus Tubulin beta 2C chain 0.0265 0.0165 0.0164
Onchocerca volvulus Neuropeptide F receptor homolog 0.0217 0.0132 0.1334
Brugia malayi neuropeptide F receptor 0.0217 0.0132 0.0727
Schistosoma mansoni lipoxygenase 0.0028 0.0005 0.0006
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.7181 0.4838 1
Trypanosoma cruzi Aph-1 protein, putative 0.0324 0.0204 1
Trichomonas vaginalis glucosylceramidase, putative 0.0222 0.0136 0.1369
Schistosoma mansoni hypothetical protein 0.0402 0.0257 0.0453
Brugia malayi Thioredoxin reductase 0.007 0.0033 0.0179
Onchocerca volvulus 0.0077 0.0037 0.0371
Loa Loa (eye worm) hypothetical protein 0.021 0.0128 0.0701
Echinococcus granulosus mothers against decapentaplegic 5 0.0039 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0048 0.0018 0.01
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0029 0.0005 0.0007
Entamoeba histolytica hypothetical protein 0.0124 0.0069 0.4194
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0402 0.0257 0.0256
Echinococcus multilocularis peroxisome assembly protein 26 0.0181 0.0108 0.0107
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Brugia malayi nuclear hormone receptor 0.098 0.0648 0.3557
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0035 0.0009 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0217 0.0132 0.0232
Echinococcus multilocularis survival motor neuron protein 1 0.0222 0.0135 0.0134
Trichomonas vaginalis tubulin epsilon chain, putative 0.0181 0.0108 0.1088
Plasmodium vivax pyruvate kinase, putative 0.0088 0.0045 0.2639
Trypanosoma brucei DNA polymerase IV, putative 0.0051 0.002 0.0896
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.098 0.0648 0.0647
Chlamydia trachomatis UDP-3-O-acylglucosamine N-acyltransferase 0.0034 0.0009 0.1604
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0197 0.0119 0.0208
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0009 0.0086
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0159 0.0093 0.0188
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Onchocerca volvulus 0.1212 0.0805 0.8145
Echinococcus granulosus Nuclear hormone receptor HR96 0.0457 0.0294 0.0293
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0124 0.0069 0.0068
Mycobacterium ulcerans hypothetical protein 0.0034 0.0009 0.0014
Onchocerca volvulus Pyruvate kinase homolog 0.0088 0.0045 0.0447
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0457 0.0294 0.0293
Echinococcus multilocularis fmrfamide receptor 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0051 0.002 0.0199
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0013 0.0125
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0068 0.0032 0.1467
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus granulosus hypothetical protein 0.0704 0.0461 0.046
Loa Loa (eye worm) hypothetical protein 0.0122 0.0068 0.0373
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0023 0.0001 0.0011
Onchocerca volvulus 0.0217 0.0132 0.1334
Loa Loa (eye worm) CYP4Cod1 0.0107 0.0058 0.0319
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0029 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Mycobacterium leprae putative cytochrome p450 0.0068 0.0031 0.006
Schistosoma mansoni biogenic amine receptor 0.0217 0.0132 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0222 0.0136 0.1369
Echinococcus granulosus mitogen activated protein kinase 0.0068 0.0032 0.003
Trichomonas vaginalis tubulin alpha chain, putative 0.0077 0.0037 0.0375
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0071 0.0033 0.0345
Echinococcus granulosus alpha tubulin 0.0181 0.0108 0.0107
Schistosoma mansoni tubulin subunit alpha 0.0181 0.0108 0.0188
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0426 0.0273 0.1501
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0028 0.0004 0.0003
Brugia malayi hypothetical protein 0.0034 0.0009 0.0048
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.005 0.0019 0.0921
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0217 0.0132 0.0131
Trypanosoma brucei cAMP-specific phosphodiesterase 0.005 0.0019 0.0851
Giardia lamblia Hypothetical protein 0.005 0.0019 0.0665
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0287 0.0179 0.0986
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.005 0.0019 0.0018
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0108 0.0058 0.0057
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.005 0.0019 0.0921
Schistosoma mansoni dynactin subunit P25 0.0034 0.0009 0.0013
Plasmodium falciparum tubulin delta chain, putative 0.0059 0.0025 0.144
Schistosoma mansoni cytochrome P450 0.0068 0.0031 0.0053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.0062 0.0107
Loa Loa (eye worm) tubulin beta-1 chain 0.0265 0.0165 0.0904
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.005 0.0019 0.0105
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0034 0.0009 0.0341
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus granulosus lipoxygenase domain containing protein 0.0028 0.0005 0.0003
Toxoplasma gondii alpha tubulin TUBA1 0.0181 0.0108 0.1161
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.053 0.0343 0.0342
Brugia malayi eIF4-gamma/eIF5/eIF2-epsilon family protein 0.0034 0.0009 0.0048
Mycobacterium ulcerans lipase LipD 0.0113 0.0062 0.0124
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0059 0.0025 0.0048
Loa Loa (eye worm) nucleotidyl transferase 0.0035 0.0009 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0009 0.0414
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0402 0.0257 0.0256
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0034 0.0009 0.0086
Echinococcus granulosus tubulin alpha chain 0.0181 0.0108 0.0107
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0217 0.0132 0.0232
Giardia lamblia DINP protein human, muc B family 0.0051 0.002 0.07
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0032
Brugia malayi conserved hypotetical protein 0.0457 0.0294 0.1616
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0002 0.0045
Plasmodium falciparum ataxin-2 like protein, putative 0.0069 0.0033 0.1883
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0217 0.0132 0.1334
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0014
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.8395 0.5658 1
Brugia malayi Importin beta-1 subunit 0.0027 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0014
Plasmodium vivax delta tubulin, putative 0.0059 0.0025 0.144
Schistosoma mansoni intermediate filament proteins 0.0115 0.0063 0.011
Schistosoma mansoni hypothetical protein 0.0028 0.0005 0.0006
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Onchocerca volvulus 0.0115 0.0063 0.063
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0093 0.0049 0.0084
Echinococcus multilocularis transcription factor Dp 1 0.0033 0.0008 0.0006
Loa Loa (eye worm) beta-tubulin 0.0265 0.0165 0.0904
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0029 0.0005 0.0007
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0016 0.0088
Echinococcus granulosus allatostatin A receptor 0.0217 0.0132 0.0131
Schistosoma mansoni hypothetical protein 0.0068 0.0031 0.0053
Schistosoma mansoni lamin 0.0115 0.0063 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0012 0.012
Trichomonas vaginalis tubulin alpha chain, putative 0.0077 0.0037 0.0375
Loa Loa (eye worm) transcription factor SMAD2 0.0567 0.0369 0.2024
Brugia malayi hypothetical protein 0.0045 0.0016 0.0087
Schistosoma mansoni tubulin subunit alpha 0.0181 0.0108 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus granulosus tubulin alpha chain 0.0181 0.0108 0.0107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1847 0.1234 0.1233
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0028 0.0004 0.0254
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0029 0.0005 0.0029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0217 0.0132 0.0131
Echinococcus granulosus transcription factor Dp 1 0.0033 0.0008 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0013 0.0644
Echinococcus granulosus neuropeptide receptor 0.0217 0.0132 0.0131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0217 0.0132 0.0232
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0217 0.0132 0.0232
Toxoplasma gondii isocitrate dehydrogenase 0.015 0.0087 0.0932
Schistosoma mansoni chromobox protein 0.0051 0.002 0.0034
Echinococcus multilocularis Tubulin beta 2C chain 0.0265 0.0165 0.0164
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0029 0.0005 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0076
Toxoplasma gondii hypothetical protein 0.008 0.004 0.0414
Trypanosoma cruzi pyruvate kinase 2, putative 0.0088 0.0045 0.2183
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0055 0.0023 0.0021
Loa Loa (eye worm) isocitrate dehydrogenase 0.015 0.0087 0.0477
Schistosoma mansoni gamma-secretase subunit aph-1 0.0831 0.0547 0.0964
Loa Loa (eye worm) tubulin alpha 2 0.0122 0.0068 0.0373
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0013 0.0012
Brugia malayi Tubulin alpha chain 0.0059 0.0025 0.0139
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.0005 0.0007
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0034 0.0009 0.0014
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0071 0.0033 0.1932
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.015 0.0087 0.0086
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0457 0.0294 0.0518
Echinococcus granulosus tm gpcr rhodopsin 0.0217 0.0132 0.0131
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0004 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0068 0.0031 0.0061
Schistosoma mansoni mannose-1-phosphate guanyltransferase 0.0035 0.0009 0.0015
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0068 0.0031 0.0061
Brugia malayi hypothetical protein 0.0523 0.0339 0.1862
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0029 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0104 0.0056 0.0307
Echinococcus granulosus ubiquitin specific protease 41 0.0055 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0005 0.0025
Trypanosoma brucei zeta tubulin 0.0059 0.0025 0.1158
Toxoplasma gondii cytochrome p450 superfamily protein 0.1374 0.0914 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0055 0.0023 0.0652
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0035 0.0009 0.0448
Plasmodium falciparum thioredoxin reductase 0.007 0.0033 0.1885
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0009 0.0368
Brugia malayi nuclear receptor NHR-88 0.098 0.0648 0.3557
Echinococcus multilocularis neuropeptides capa receptor 0.0217 0.0132 0.0131
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.007 0.0033 0.0063
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.005 0.0019 0.0921
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0068 0.0031 0.0061
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0028 0.0004 0.0161
Toxoplasma gondii histone lysine methyltransferase SET1 0.0226 0.0138 0.1493
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0217 0.0132 0.0232
Leishmania major hypothetical protein, conserved 0.005 0.0019 0.0547
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0023 0.0001 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0303 0.019 0.0335
Echinococcus multilocularis L aminoadipate semialdehyde 0.0251 0.0155 0.0154
Brugia malayi nuclear receptor RXR 0.0523 0.0339 0.1862
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0241 0.0148 0.7253
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.015 0.0087 0.0086
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.7181 0.4838 1
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Schistosoma mansoni patched 1 0.0039 0.0012 0.0019
Plasmodium falciparum alpha tubulin 2 0.0181 0.0108 0.65
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0068 0.0031 0.0061
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0034 0.0009 0.0514
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Loa Loa (eye worm) hypothetical protein 0.005 0.0019 0.0105
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0026 0.0003 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0051 0.002 0.0965
Trypanosoma brucei DNA polymerase eta, putative 0.0051 0.002 0.0896
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus Tubulin beta 2C chain 0.0265 0.0165 0.0164
Entamoeba histolytica serine acetyltransferase, putative 0.0034 0.0009 0.0514
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.015 0.0087 0.522
Trypanosoma cruzi Translation initiation factor eIF-2B subunit epsilon, putative 0.0035 0.0009 0.0448
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.002 0.011
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0029 0.0005 0.0302
Mycobacterium leprae conserved hypothetical protein 0.0113 0.0062 0.0123
Brugia malayi G-protein coupled receptor 0.0217 0.0132 0.0727
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0032 0.0316
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0056 0.0024 0.0022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0002 0.0132
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0108 0.0058 0.0589
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0108 0.0058 0.0321
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.1058
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0068 0.0031 0.0061
Onchocerca volvulus 0.0197 0.0119 0.1198
Echinococcus multilocularis mothers against decapentaplegic 5 0.0039 0.0012 0.0011
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0013 0.0563
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0051 0.002 0.0574
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.0063
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0023 0.0001 0.0008
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus multilocularis pyruvate kinase 0.0069 0.0032 0.0031
Echinococcus multilocularis tubulin epsilon chain 0.0135 0.0077 0.0076
Toxoplasma gondii beta-1 tubulin, putative 0.0265 0.0165 0.1786
Echinococcus granulosus tubulin alpha chain 0.0181 0.0108 0.0107
Brugia malayi tubulin alpha-2 chain 0.0181 0.0108 0.0591
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Onchocerca volvulus 0.0115 0.0063 0.0635
Brugia malayi beta-tubulin, identical 0.0265 0.0165 0.0904
Schistosoma mansoni smad1 5 8 and 0.0039 0.0012 0.0019
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0005 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0009 0.0086
Trypanosoma brucei beta tubulin 0.0265 0.0165 0.8046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0545 0.0354 0.0624
Leishmania major DNA polymerase eta, putative 0.0051 0.002 0.0574
Trichomonas vaginalis esterase, putative 0.0113 0.0062 0.0624
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0009 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0068 0.0031 0.0061
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0008 0.0076
Trichomonas vaginalis tubulin alpha chain, putative 0.0077 0.0037 0.0375
Schistosoma mansoni lamin 0.0115 0.0063 0.011
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0029 0.0005 0.0006
Chlamydia trachomatis acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase 0.0034 0.0009 0.1604
Loa Loa (eye worm) hypothetical protein 0.0181 0.0108 0.0591
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.0062 0.0124
Brugia malayi sulfakinin receptor protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Plasmodium vivax dynactin subunit 5, putative 0.0034 0.0009 0.0423
Echinococcus granulosus thyroid hormone receptor alpha 0.0663 0.0434 0.0433
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0029 0.0005 0.0037
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0034 0.0008 0.0399
Leishmania major cytochrome p450-like protein 0.0107 0.0058 0.1684
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0068 0.0031 0.0061
Treponema pallidum licC protein (licC) 0.1252 0.0832 1
Brugia malayi alpha-tubulin 0.0181 0.0108 0.0591
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0002 0.0132
Giardia lamblia Rab geranylgeranyltransferase 0.0108 0.0058 0.2187
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0002 0.0001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.0062 0.0124
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0031 0.0007 0.0005
Mycobacterium ulcerans hypothetical protein 0.0025 0.0002 0.0001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0092 0.0048 0.2877
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0056 0.0024 0.013
Schistosoma mansoni myosin xvIII 0.0217 0.0132 0.0232
Trypanosoma brucei DNA polymerase IV, putative 0.0051 0.002 0.0896
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0029 0.0005 0.0302
Trichomonas vaginalis tubulin beta chain, putative 0.0077 0.0037 0.0375
Trypanosoma cruzi tubulin delta chain 0.0059 0.0025 0.1226
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Loa Loa (eye worm) hypothetical protein 0.004 0.0012 0.0068
Trichomonas vaginalis tubulin beta chain, putative 0.0181 0.0108 0.1088
Brugia malayi Nuclear hormone receptor family member nhr-1 0.098 0.0648 0.3557
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0062 0.0624
Brugia malayi Cytochrome P450 family protein 0.0107 0.0058 0.0319
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0029 0.0005 0.0243
Echinococcus granulosus Smad4 0.0039 0.0012 0.0011
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0033 0.0064
Trichomonas vaginalis tubulin beta chain, putative 0.0181 0.0108 0.1088
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0457 0.0294 0.0293
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.005 0.0019 0.0018
Schistosoma mansoni hypothetical protein 0.0803 0.0528 0.0931
Onchocerca volvulus 0.0457 0.0294 0.2973
Echinococcus multilocularis mitogen activated protein kinase 0.0068 0.0032 0.003
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0011 0.0017
Leishmania major hypothetical protein, conserved 0.0069 0.0033 0.0939
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus multilocularis beta tubulin 0.0265 0.0165 0.0164
Brugia malayi Cytochrome P450 family protein 0.0219 0.0133 0.0732
Trypanosoma cruzi PAB1-binding protein , putative 0.0069 0.0033 0.158
Trypanosoma cruzi DNA polymerase kappa, putative 0.0051 0.002 0.0965
Echinococcus granulosus survival motor neuron protein 1 0.0222 0.0135 0.0134
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.005 0.0019 0.0547
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0029 0.0005 0.0168
Schistosoma mansoni growth hormone secretagogue receptor 0.0217 0.0132 0.0232
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.005 0.0019 0.0032
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.7181 0.4838 1
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0029 0.0005 0.0027
Brugia malayi cytoplasmic intermediate filament protein 0.0062 0.0027 0.015
Echinococcus multilocularis ubiquitin specific protease 41 0.0055 0.0023 0.0021
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0063 0.1814
Echinococcus multilocularis Tubulin alpha 1 chain 0.0181 0.0108 0.0107
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0181 0.0108 0.1088
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0002 0.0001
Echinococcus granulosus gamma secretase subunit aph 1 0.0831 0.0547 0.0546
Schistosoma mansoni nuclear receptor nhr-48 0.0457 0.0294 0.0518
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0267 0.0166 0.0911
Echinococcus multilocularis Smad4 0.0039 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.1212 0.0805 0.4419
Brugia malayi Tubulin alpha chain 0.0181 0.0108 0.0591
Schistosoma mansoni opsin-like receptor 0.0217 0.0132 0.0232
Schistosoma mansoni microtubule-associated protein tau 0.1715 0.1144 0.2021
Brugia malayi hypothetical protein 0.0034 0.0009 0.0048
Entamoeba histolytica acetyltransferase, putative 0.0034 0.0009 0.0514
Loa Loa (eye worm) pyruvate kinase-PB 0.0061 0.0027 0.0148
Loa Loa (eye worm) hypothetical protein 0.0113 0.0062 0.034
Schistosoma mansoni bromodomain containing protein 0.0053 0.0021 0.0036
Schistosoma mansoni pyruvate kinase 0.0045 0.0016 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0009 0.0423
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0056 0.0024 0.1144
Trypanosoma cruzi DNA polymerase kappa, putative 0.0051 0.002 0.0965
Echinococcus granulosus tubulin alpha 1C chain 0.0181 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0457 0.0294 0.1616
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0023 0.0001 0.0011
Brugia malayi Pre-SET motif family protein 0.0189 0.0113 0.0622
Treponema pallidum gamma-glutamyl phosphate reductase 0.0029 0.0005 0.0041
Onchocerca volvulus 0.0023 0.0001 0.0007
Brugia malayi TAR-binding protein 0.0105 0.0057 0.0311
Giardia lamblia Gamma tubulin 0.0135 0.0077 0.2904
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0108 0.0058 0.0589
Loa Loa (eye worm) hypothetical protein 0.098 0.0648 0.3557
Brugia malayi Nuclear hormone receptor E75 0.0457 0.0294 0.1616
Schistosoma mansoni polycystin 1-related 0.0028 0.0005 0.0006
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0068 0.0031 0.0061
Loa Loa (eye worm) tubulin beta chain 0.0059 0.0025 0.0139
Schistosoma mansoni biogenic amine receptor 0.0217 0.0132 0.0232
Plasmodium falciparum cGMP-specific phosphodiesterase 0.005 0.0019 0.1058
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Schistosoma mansoni tubulin subunit beta 0.0265 0.0165 0.0289
Brugia malayi GDP-mannose pyrophosphorylase B 0.0035 0.0009 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-49 0.098 0.0648 0.3557
Schistosoma mansoni nuclear receptor 0.0457 0.0294 0.0518
Echinococcus granulosus Tubulin alpha 1 chain 0.0181 0.0108 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.098 0.0648 0.3557
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0014 0.0013
Leishmania major alpha tubulin 0.0181 0.0108 0.313
Echinococcus granulosus tubulin beta 4A class IVa 0.0265 0.0165 0.0164
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0029 0.0005 0.0007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0063 0.3052
Echinococcus granulosus tubulin beta 1 chain 0.0265 0.0165 0.0164
Giardia lamblia Delta tubulin 0.0059 0.0025 0.0905
Loa Loa (eye worm) hypothetical protein 0.0426 0.0273 0.1501
Brugia malayi hypothetical protein 0.0069 0.0033 0.0179
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0035 0.0009 0.0448
Echinococcus granulosus tubulin alpha 3 chain 0.0181 0.0108 0.0107
Echinococcus multilocularis smad 0.0039 0.0012 0.0011
Trypanosoma brucei epsilon tubulin 0.0135 0.0077 0.3716
Plasmodium vivax hypothetical protein, conserved 0.0113 0.0062 0.3688
Echinococcus multilocularis tubulin alpha 1C chain 0.0181 0.0108 0.0107
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0032 0.0054
Schistosoma mansoni amine GPCR 0.0217 0.0132 0.0232
Echinococcus multilocularis tubulin alpha 1C chain 0.0181 0.0108 0.0107
Echinococcus multilocularis musashi 0.0115 0.0063 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.0051 0.002 0.0965
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.098 0.0648 0.1143
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0047
Brugia malayi photoreceptor-specific nuclear receptor 0.098 0.0648 0.3557
Plasmodium falciparum phosphodiesterase delta, putative 0.005 0.0019 0.1058
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0068 0.0031 0.0061
Schistosoma mansoni hypothetical protein 0.0034 0.0009 0.0013
Brugia malayi hypothetical protein 0.0124 0.0069 0.038
Plasmodium vivax phosphodiesterase gamma, putative 0.005 0.0019 0.1058
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.2716 0.1821 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.098 0.0648 0.3557
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0023 0.0001 0.0011
Echinococcus multilocularis nuclear receptor nhr 48 0.0457 0.0294 0.0293
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0013 0.0024
Leishmania major aldehyde dehydrogenase, putative 0.0029 0.0005 0.0145
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0217 0.0132 0.0232
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0029 0.0005 0.0037
Loa Loa (eye worm) hypothetical protein 0.0303 0.019 0.1046
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0068 0.0031 0.0061
Echinococcus granulosus dynactin 5 p25 0.0034 0.0009 0.0008
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0029 0.0005 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.098 0.0648 0.0647
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0068 0.0031 0.0904
Mycobacterium tuberculosis Conserved protein 0.0113 0.0062 0.0124
Echinococcus granulosus tubulin alpha 0.0135 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0545 0.0354 0.1945
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.005 0.0019 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0146 0.0084 0.0847
Echinococcus granulosus geminin 0.185 0.1235 0.1234
Plasmodium falciparum phosphodiesterase gamma, putative 0.005 0.0019 0.1058
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0008 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0068 0.0031 0.0061
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.098 0.0648 0.0647
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.005 0.0019 0.0189
Schistosoma mansoni tubulin subunit beta 0.0265 0.0165 0.0289
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.005 0.0019 0.019
Schistosoma mansoni egf-like domain protein 0.0026 0.0003 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0062 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0003 0.0028
Brugia malayi beta-lactamase family protein 0.0113 0.0062 0.034
Brugia malayi beta-lactamase family protein 0.0113 0.0062 0.034
Brugia malayi Aldehyde dehydrogenase protein 4 0.0029 0.0005 0.0029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0402 0.0257 0.1413
Loa Loa (eye worm) neuropeptide F receptor 0.0217 0.0132 0.0727
Trichomonas vaginalis glucosylceramidase, putative 0.0222 0.0136 0.1369
Echinococcus granulosus rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Echinococcus multilocularis neuropeptide s receptor 0.2734 0.1833 0.1832
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.015 0.0087 0.42
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0023 0.0001 0.0008
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0068 0.0031 0.0061
Onchocerca volvulus 0.0217 0.0132 0.1334
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0029 0.0005 0.0243
Echinococcus multilocularis pyruvate kinase 0.0045 0.0016 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0009 0.0368
Brugia malayi Nuclear hormone receptor-like 1 0.0523 0.0339 0.1862
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.098 0.0648 0.3557
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0217 0.0132 0.0727
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.015 0.0087 0.522
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0029 0.0005 0.0029
Brugia malayi Bromodomain containing protein 0.0028 0.0005 0.0025
Brugia malayi Tubulin alpha-2 chain 0.0181 0.0108 0.0591
Brugia malayi MH1 domain containing protein 0.0039 0.0012 0.0064
Trichomonas vaginalis pyruvate kinase, putative 0.0088 0.0045 0.0451
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.098 0.0648 0.3557
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0457 0.0294 0.0293
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0059 0.0025 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-14 0.098 0.0648 0.3557
Echinococcus multilocularis G-protein coupled receptor, putative 0.0217 0.0132 0.0131
Giardia lamblia Beta tubulin 0.0265 0.0165 0.6288
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0055 0.0023 0.136
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0217 0.0132 0.0131
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0006 0.0057
Brugia malayi Cytochrome P450 family protein 0.0107 0.0058 0.0319
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0013 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.053 0.0343 0.0605
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0158 0.0092 0.0091
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.001 0.0016
Leishmania major epsilon tubulin, putative 0.0135 0.0077 0.2237
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.005 0.0019 0.0851
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0407 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0005 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0004 0.002
Echinococcus multilocularis Niemann Pick C1 protein 0.0092 0.0048 0.0046
Echinococcus multilocularis geminin 0.185 0.1235 0.1234
Schistosoma mansoni thyroid hormone receptor 0.098 0.0648 0.1143
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0009 0.0086
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0159 0.0093 0.0188
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0019 0.0851
Giardia lamblia Alpha-tubulin 0.0181 0.0108 0.4087
Trypanosoma brucei alpha tubulin, putative 0.0077 0.0037 0.1753
Leishmania major pyruvate kinase 0.0088 0.0045 0.1298
Schistosoma mansoni coup transcription factor 0.098 0.0648 0.1143
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.005 0.0019 0.0018
Brugia malayi Heterochromatin protein 1 0.0051 0.002 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0011 0.0061
Loa Loa (eye worm) alpha-tubulin 0.0181 0.0108 0.0591
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0029 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0023 0.0226
Loa Loa (eye worm) heterochromatin protein 1 0.0051 0.002 0.011
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Brugia malayi ecdysteroid receptor 0.1201 0.0797 0.4377
Trichomonas vaginalis tubulin, putative 0.0077 0.0037 0.0375
Echinococcus granulosus polycomb protein SCMH1 0.0038 0.0011 0.001
Echinococcus multilocularis Polycystic kidney disease protein 0.0028 0.0005 0.0003
Mycobacterium tuberculosis Possible siderophore-binding protein 0.0034 0.0009 0.0014
Brugia malayi Isocitrate dehydrogenase 0.015 0.0087 0.0477
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0002 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.002 0.0896
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0068 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0044 0.0015 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.098 0.0648 0.0647
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0002 0.0063
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0034 0.0009 0.0014
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.005 0.0019 0.0032
Onchocerca volvulus 0.0251 0.0155 0.1566
Echinococcus granulosus GPCR family 2 0.0402 0.0257 0.0256
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0013 0.0131
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0035 0.0009 0.005
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0004 0.0093
Echinococcus granulosus dnaJ subfamily B 0.0803 0.0528 0.0527
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Echinococcus multilocularis rhodopsin orphan GPCR 0.0217 0.0132 0.0131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0217 0.0132 0.0232
Entamoeba histolytica acetyltransferase, putative 0.0034 0.0009 0.0514
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0124 0.0069 0.0068
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0035 0.0009 0.0008
Onchocerca volvulus 0.0113 0.0062 0.062
Giardia lamblia Alpha-tubulin 0.0181 0.0108 0.4087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0217 0.0132 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-25 0.098 0.0648 0.3557
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Schistosoma mansoni RAR-like nuclear receptor 0.098 0.0648 0.1143
Echinococcus granulosus sex peptide receptor 0.0217 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.1201 0.0797 0.4377
Loa Loa (eye worm) hypothetical protein 0.0869 0.0573 0.3144
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0068 0.0031 0.0061
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0023 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0001 0.0008
Brugia malayi Tubulin beta chain 0.0059 0.0025 0.0139
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Mycobacterium tuberculosis Conserved protein 0.0113 0.0062 0.0124
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0002 0.0016
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0051 0.002 0.011
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0013 0.0024
Onchocerca volvulus 0.0217 0.0132 0.1334
Plasmodium vivax thioredoxin reductase, putative 0.007 0.0033 0.1885
Echinococcus granulosus neuropeptides capa receptor 0.0217 0.0132 0.0131
Schistosoma mansoni cpg binding protein 0.0122 0.0068 0.0119
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.005 0.0019 0.019
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0241 0.0148 0.7232
Echinococcus multilocularis hypothetical protein 0.0181 0.0108 0.0107
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0088 0.0045 0.0089
Brugia malayi nuclear hormone receptor family member odr-7 0.0457 0.0294 0.1616
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.005 0.0019 0.0921
Schistosoma mansoni transcription factor LCR-F1 0.0124 0.0069 0.012
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Trypanosoma cruzi cytochrome P450, putative 0.0107 0.0058 0.2834
Schistosoma mansoni neuropeptide receptor 0.0217 0.0132 0.0232
Trypanosoma cruzi zeta tubulin, putative 0.0059 0.0025 0.1226
Echinococcus multilocularis cpg binding protein 0.0122 0.0068 0.0067
Echinococcus multilocularis fibrillin 1 0.0029 0.0005 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0217 0.0132 0.0131
Echinococcus granulosus thioredoxin glutathione reductase 0.007 0.0033 0.0031
Leishmania major beta tubulin 0.0265 0.0165 0.4791
Brugia malayi isocitrate dehydrogenase 0.015 0.0087 0.0477
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0545 0.0354 0.0624
Treponema pallidum cell division protein FtsZ 0.0059 0.0025 0.0283
Schistosoma mansoni biogenic amine (5HT) receptor 0.0483 0.0312 0.0549
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0135 0.0077 0.0825
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0035 0.0009 0.0008
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.005 0.0019 0.0105
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0056 0.0024 0.1144
Trypanosoma brucei beta tubulin 0.0265 0.0165 0.8046
Brugia malayi mbt repeat family protein 0.0038 0.0011 0.0063
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0013 0.0787
Echinococcus multilocularis chromobox protein 1 0.0051 0.002 0.0019
Echinococcus granulosus neuropeptide receptor 0.0217 0.0132 0.0131
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0056 0.0024 0.1076
Echinococcus multilocularis neuropeptide receptor 0.0217 0.0132 0.0131
Schistosoma mansoni hypothetical protein 0.0038 0.0011 0.0018
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0055 0.0023 0.1096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0023 0.0226
Loa Loa (eye worm) hypothetical protein 0.021 0.0128 0.0701
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0023 0.0001 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0189 0.0113 0.1223
Loa Loa (eye worm) TYRA-2 protein 0.0217 0.0132 0.0727
Loa Loa (eye worm) hypothetical protein 0.0217 0.0132 0.0727
Schistosoma mansoni alpha-1 adrenergic receptor 0.0217 0.0132 0.0232
Echinococcus multilocularis mitogen activated protein kinase 3 0.0068 0.0032 0.003
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0108 0.0058 0.354
Echinococcus granulosus mannose 1 phosphate guanyltransferase 0.0035 0.0009 0.0008
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0029 0.0005 0.0006
Loa Loa (eye worm) MH1 domain-containing protein 0.0039 0.0012 0.0064
Brugia malayi hypothetical protein 0.0034 0.0009 0.0048
Brugia malayi hypothetical protein 0.0217 0.0132 0.0727
Echinococcus multilocularis lipoxygenase domain containing protein 0.0028 0.0005 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0032 0.0316
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.005 0.002 0.0018
Toxoplasma gondii hypothetical protein 0.0039 0.0012 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0105 0.0057 0.0098
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0013 0.0131
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.005 0.0019 0.019
Echinococcus granulosus 7TM GPCR rhodopsin 0.0217 0.0132 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0019 0.0921
Echinococcus granulosus Nuclear hormone receptor HR96 0.0457 0.0294 0.0293
Mycobacterium ulcerans aldehyde dehydrogenase 0.053 0.0343 0.0706
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0062 0.0027 0.015
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0029
Brugia malayi Bromodomain containing protein 0.0062 0.0027 0.0149

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.51 uM Ability to inhibit histamine-induced contractions of isolated guinea pig ileum ChEMBL. 7861415
IC50 (functional) > 100 uM Test against PAF-induced aggregation of rabbit platelets in vitro ChEMBL. 7861415

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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