Detailed information for compound 376052

Basic information

Technical information
  • TDR Targets ID: 376052
  • Name: 3-amino-7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolid in-1-yl]-1-cyclopropyl-6-fluoro-8-methylquina zoline-2,4-dione
  • MW: 361.414 | Formula: C18H24FN5O2
  • H donors: 2 H acceptors: 2 LogP: 1.09 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H]([C@@H]1CCN(C1)c1c(F)cc2c(c1C)n(C1CC1)c(=O)n(c2=O)N)N
  • InChi: 1S/C18H24FN5O2/c1-9-15-13(17(25)24(21)18(26)23(15)12-3-4-12)7-14(19)16(9)22-6-5-11(8-22)10(2)20/h7,10-12H,3-6,8,20-21H2,1-2H3/t10-,11+/m0/s1
  • InChiKey: SMONLCFJGCJROJ-WDEREUQCSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-amino-7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methyl-quinazoline-2,4-dione
  • 3-amino-7-[(3R)-3-[(1S)-1-aminoethyl]-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-8-methylquinazoline-2,4-dione
  • 3-azanyl-7-[(3R)-3-[(1S)-1-azanylethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methyl-quinazoline-2,4-dione
  • 3-amino-7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidino]-1-cyclopropyl-6-fluoro-8-methyl-quinazoline-2,4-quinone
  • 3-amino-7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methyl-quinazoline-2,4-quinone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli DNA gyrase (type II topoisomerase), subunit A Starlite/ChEMBL References
Escherichia coli DNA gyrase, subunit B References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium knowlesi DNA gyrase subunit B, putative Get druggable targets OG5_128755 All targets in OG5_128755
Treponema pallidum DNA gyrase, subunit A (gyrA) Get druggable targets OG5_129568 All targets in OG5_129568
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) Get druggable targets OG5_129568 All targets in OG5_129568
Plasmodium vivax DNA gyrase subunit A, putative Get druggable targets OG5_129568 All targets in OG5_129568
Mycobacterium ulcerans DNA gyrase subunit A Get druggable targets OG5_129568 All targets in OG5_129568
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein Get druggable targets OG5_129568 All targets in OG5_129568
Neospora caninum DNA gyrase subunit A, putative Get druggable targets OG5_129568 All targets in OG5_129568
Leishmania mexicana mitochondrial DNA topoisomerase II Get druggable targets OG5_128755 All targets in OG5_128755
Plasmodium berghei DNA gyrase subunit B, putative Get druggable targets OG5_128755 All targets in OG5_128755
Plasmodium berghei DNA gyrase subunit A, putative Get druggable targets OG5_129568 All targets in OG5_129568
Theileria parva DNA gyrase subunit B, putative Get druggable targets OG5_128755 All targets in OG5_128755
Plasmodium falciparum DNA gyrase subunit B Get druggable targets OG5_128755 All targets in OG5_128755
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A Get druggable targets OG5_129568 All targets in OG5_129568
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative Get druggable targets OG5_128755 All targets in OG5_128755
Theileria parva DNA gyrase subunit A, putative Get druggable targets OG5_129568 All targets in OG5_129568
Leishmania major mitochondrial DNA topoisomerase II Get druggable targets OG5_128755 All targets in OG5_128755
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB Get druggable targets OG5_128755 All targets in OG5_128755
Babesia bovis DNA gyrase subunit B, putative Get druggable targets OG5_128755 All targets in OG5_128755
Leishmania donovani mitochondrial DNA topoisomerase II Get druggable targets OG5_128755 All targets in OG5_128755
Plasmodium knowlesi DNA gyrase subunit A, putative Get druggable targets OG5_129568 All targets in OG5_129568
Chlamydia trachomatis DNA gyrase subunit B Get druggable targets OG5_128755 All targets in OG5_128755
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative Get druggable targets OG5_128755 All targets in OG5_128755
Leishmania braziliensis mitochondrial DNA topoisomerase II Get druggable targets OG5_128755 All targets in OG5_128755
Neospora caninum hypothetical protein Get druggable targets OG5_128755 All targets in OG5_128755
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein Get druggable targets OG5_128755 All targets in OG5_128755
Babesia bovis DNA gyrase A subunit, putative Get druggable targets OG5_129568 All targets in OG5_129568
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) Get druggable targets OG5_128755 All targets in OG5_128755
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) Get druggable targets OG5_128755 All targets in OG5_128755
Trypanosoma brucei gambiense DNA topoisomerase II, putative Get druggable targets OG5_128755 All targets in OG5_128755
Mycobacterium ulcerans DNA gyrase subunit B Get druggable targets OG5_128755 All targets in OG5_128755
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) Get druggable targets OG5_129568 All targets in OG5_129568
Treponema pallidum DNA gyrase, subunit B (gyrB) Get druggable targets OG5_128755 All targets in OG5_128755
Chlamydia trachomatis DNA gyrase subunit A Get druggable targets OG5_129568 All targets in OG5_129568
Plasmodium falciparum DNA gyrase subunit A Get druggable targets OG5_129568 All targets in OG5_129568
Plasmodium yoelii DNA topoisomerase II, putative Get druggable targets OG5_128755 All targets in OG5_128755
Trypanosoma brucei DNA topoisomerase ii Get druggable targets OG5_128755 All targets in OG5_128755
Plasmodium vivax DNA gyrase subunit B, putative Get druggable targets OG5_128755 All targets in OG5_128755
Trypanosoma congolense DNA topoisomerase II, putative Get druggable targets OG5_128755 All targets in OG5_128755
Leishmania infantum mitochondrial DNA topoisomerase II Get druggable targets OG5_128755 All targets in OG5_128755
Plasmodium yoelii DNA gyrase subunit a-related Get druggable targets OG5_129568 All targets in OG5_129568
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi ABC transporter family protein 0.0036 0.0117 0.0251
Schistosoma mansoni phd/f-box containing protein 0.0028 0.0068 0.0135
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0028 0.0068 0.0183
Onchocerca volvulus 0.0209 0.1241 0.3485
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0022 0.0026 0.0007
Trypanosoma brucei trypanothione reductase 0.0038 0.013 0.0298
Loa Loa (eye worm) hypothetical protein 0.0033 0.0095 0.0095
Echinococcus granulosus transient receptor potential cation channel 0.0042 0.0153 0.0208
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0264 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0157 0.0374
Brugia malayi hypothetical protein 0.0129 0.0719 0.1545
Echinococcus granulosus tm gpcr rhodopsin 0.08 0.5082 0.688
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Echinococcus granulosus adam 17 protease 0.0814 0.5177 0.7009
Echinococcus granulosus voltage gated potassium channel 0.0164 0.0952 0.1289
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.0187 0.0374
Echinococcus granulosus two pore calcium channel protein 2 0.0042 0.0153 0.0208
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0149 0.0853 0.2383
Schistosoma mansoni tyrosine kinase 0.0181 0.1059 0.2117
Brugia malayi F/Y-rich N-terminus family protein 0.0043 0.0163 0.035
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0024 0.0036 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0119 0.0266
Echinococcus granulosus glycine receptor subunit alpha 1 0.0069 0.0328 0.0444
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0325 0.1999 0.5581
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0451 0.2814 0.2814
Echinococcus multilocularis glycine receptor subunit beta 0.0069 0.0328 0.0444
Schistosoma mansoni voltage-gated potassium channel 0.059 0.3722 0.7439
Brugia malayi tailless protein 0.0027 0.0059 0.0127
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0119 0.0269
Chlamydia trachomatis DNA gyrase subunit B 0.01 0.0534 0.2641
Toxoplasma gondii hypothetical protein 0.0047 0.0187 0.0518
Schistosoma mansoni tyrosine kinase 0.0122 0.0678 0.1355
Brugia malayi hypothetical protein 0.0019 0.0003 0.0007
Brugia malayi 6-phosphofructokinase 0.0088 0.0452 0.097
Echinococcus granulosus c src tyrosine kinase 0.0026 0.0051 0.0068
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0024 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Brugia malayi Calcium binding EGF domain containing protein 0.0048 0.0197 0.0424
Schistosoma mansoni dihydroceramide desaturase 0.0074 0.0362 0.0724
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0364 0.1015
Echinococcus multilocularis neuropeptide receptor A26 0.0209 0.1241 0.1681
Echinococcus multilocularis lysine specific demethylase 6a 0.0028 0.0068 0.0092
Echinococcus multilocularis lysine specific demethylase 5A 0.0107 0.0577 0.0781
Entamoeba histolytica P-glyco protein 6, putative 0.0036 0.0117 0.0317
Plasmodium falciparum lysophospholipase, putative 0.008 0.0404 0.1123
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Schistosoma mansoni transient receptor potential channel 0.0042 0.0153 0.0307
Mycobacterium ulcerans hypothetical protein 0.0074 0.0364 0.1866
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0031 0.0081 0.011
Echinococcus granulosus tumor protein p63 0.0727 0.4609 0.624
Brugia malayi putative neuropeptide receptor 0.0209 0.1241 0.2667
Echinococcus multilocularis RUN 0.0038 0.0132 0.0179
Brugia malayi PHD-finger family protein 0.0088 0.0456 0.098
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Brugia malayi hypothetical protein 0.0047 0.0187 0.0402
Toxoplasma gondii hypothetical protein 0.0031 0.0082 0.0224
Toxoplasma gondii ABC1 family protein 0.0036 0.0119 0.0327
Schistosoma mansoni sodium-dependent amino acid transporter 0.0047 0.0187 0.0374
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0058 0.0257 0.0514
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.035 0.2156 0.2919
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0061 0.0278 0.0377
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0157 0.0313
Entamoeba histolytica DNA topoisomerase II, putative 0.0069 0.0329 0.0914
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Trypanosoma brucei monoglyceride lipase, putative 0.008 0.0404 0.1073
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0042 0.0153 0.0418
Brugia malayi protein-tyrosine kinase 0.0049 0.02 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Loa Loa (eye worm) doublecortin family protein 0.0038 0.0132 0.0132
Schistosoma mansoni retinoic acid receptor RXR 0.0058 0.0257 0.0514
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0566 0.3562 1
Echinococcus granulosus geminin 0.0363 0.2246 0.3041
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0276 0.1677 0.3602
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.035 0.2156 0.4631
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Schistosoma mansoni notch 0.0018 0.0003 0.0005
Echinococcus multilocularis Protein lozenge 0.0056 0.0245 0.0332
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Echinococcus granulosus lamin 0.0031 0.0082 0.0112
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Entamoeba histolytica hypothetical protein 0.0077 0.038 0.1057
Giardia lamblia Rab geranylgeranyltransferase 0.0024 0.0036 0.0094
Schistosoma mansoni survival motor neuron protein 0.0086 0.0442 0.0884
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.2373
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.0187 0.0374
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0447 0.1197
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.0197
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0036 0.0117 0.0472
Loa Loa (eye worm) solute carrier family 6 member 4 0.0276 0.1677 0.1677
Echinococcus granulosus neuropeptide receptor 0.0209 0.1241 0.1681
Brugia malayi latrophilin 2 splice variant baaae 0.0215 0.1283 0.2757
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0157 0.0427
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0059 0.0267 0.0361
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0112 0.0612 0.0612
Schistosoma mansoni DNA topoisomerase II 0.0069 0.0329 0.0658
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0116 0.0157
Toxoplasma gondii endonuclease IV APN 0.0062 0.0284 0.079
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0149 0.0853 0.4373
Loa Loa (eye worm) hypothetical protein 0.0036 0.0119 0.0119
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0119 0.0266
Loa Loa (eye worm) ion channel NompC 0.0042 0.0153 0.0153
Loa Loa (eye worm) runx1 0.0056 0.0245 0.0245
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0062 0.0284 0.0785
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0257 0.0514
Mycobacterium ulcerans transmembrane transport protein 0.0074 0.0364 0.1866
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0187 0.0512
Plasmodium falciparum cGMP-dependent protein kinase 0.0075 0.0369 0.1024
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0062 0.0287 0.1472
Trypanosoma cruzi cAMP response protein 1 0.0074 0.0364 0.1009
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.013 0.013
Echinococcus multilocularis protein jagged 2 0.0018 0.0003 0.0003
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0463 0.1293
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.0092 0.0125
Loa Loa (eye worm) hypothetical protein 0.042 0.2615 0.2615
Brugia malayi beta-lactamase family protein 0.0036 0.0119 0.0255
Echinococcus granulosus NCK adaptor protein 0.0021 0.0019 0.0025
Echinococcus multilocularis multidrug resistance protein 1 0.0036 0.0117 0.0158
Onchocerca volvulus 0.0018 0.0003 0.0007
Trypanosoma cruzi Flagellar Member 6 0.0074 0.0364 0.1009
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0069 0.0182
Onchocerca volvulus 0.0209 0.1241 0.3485
Schistosoma mansoni hypothetical protein 0.0149 0.0853 0.1704
Schistosoma mansoni thyroid hormone receptor 0.0262 0.1587 0.3172
Echinococcus multilocularis Polycystic kidney disease protein 0.0038 0.0132 0.0179
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Mycobacterium ulcerans hypothetical protein 0.0074 0.0364 0.1866
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0074 0.0364 0.0781
Brugia malayi hypothetical protein 0.0038 0.0132 0.0283
Trichomonas vaginalis set domain proteins, putative 0.0513 0.3219 0.903
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0119 0.0255
Brugia malayi jmjC domain containing protein 0.0289 0.1762 0.3786
Echinococcus multilocularis transient receptor potential cation channel 0.0042 0.0153 0.0208
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0032
Echinococcus granulosus protein jagged 2 0.0018 0.0003 0.0003
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0107 0.0287
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0022 0.0026 0.0135
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0107 0.0144
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0107 0.0107
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0676 0.3465
Echinococcus granulosus voltage dependent calcium channel 0.0042 0.0153 0.0208
Echinococcus granulosus transient receptor potential cation channel 0.0042 0.0153 0.0208
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0053 0.0225 0.238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1241 0.2481
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0069 0.0329 0.0446
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.02 0.027
Echinococcus granulosus tm gpcr rhodopsin 0.1154 0.7386 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.008 0.0404 0.1073
Plasmodium vivax DNA gyrase subunit B, putative 0.0153 0.0877 0.2451
Mycobacterium leprae Probable lipase LipE 0.0036 0.0119 0.1127
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0102 0.0545 0.6179
Echinococcus multilocularis transient receptor potential cation channel 0.0042 0.0153 0.0208
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0623 0.1738
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Plasmodium vivax PST-A protein 0.008 0.0404 0.1123
Trichomonas vaginalis taga, putative 0.0036 0.0117 0.0261
Schistosoma mansoni opsin-like receptor 0.0209 0.1241 0.2481
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0024 0.0036 0.0077
Loa Loa (eye worm) voltage-gated potassium channel 0.0042 0.0153 0.0153
Entamoeba histolytica hypothetical protein 0.0077 0.038 0.1057
Trypanosoma brucei pyruvate kinase 1 0.0027 0.0057 0.0092
Echinococcus multilocularis sodium leak channel non selective protein 0.0042 0.0153 0.0208
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0058 0.0257 0.0348
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0149 0.0853 0.2342
Loa Loa (eye worm) CYP4Cod1 0.0293 0.1789 0.1789
Mycobacterium ulcerans pyruvate kinase 0.0027 0.0057 0.0293
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0042 0.0153 0.0208
Onchocerca volvulus Protein ultraspiracle homolog 0.0058 0.0257 0.0721
Brugia malayi Cadherin domain containing protein 0.0018 0.0003 0.0005
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0209 0.1241 0.2667
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0059 0.008
Schistosoma mansoni voltage-gated cation channel 0.0042 0.0153 0.0307
Echinococcus multilocularis protein jagged 1 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Brugia malayi notch-like transmembrane receptor 0.0018 0.0003 0.0005
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0566 0.3562 1
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0119 0.0609
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.008 0.0404 0.1124
Brugia malayi Dopamine receptor 0.0209 0.1241 0.2667
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0209 0.1241 0.2481
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0074 0.0364 0.0727
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Brugia malayi Calcitonin receptor-like protein seb-1 0.0315 0.1932 0.4149
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0042 0.0153 0.0208
Plasmodium falciparum glutathione reductase 0.0038 0.013 0.0352
Trypanosoma cruzi lanosterol synthase, putative 0.007 0.0336 0.0931
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0107 0.0144
Brugia malayi Dopamine receptor protein 1 0.0209 0.1241 0.2667
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0566 0.3562 1
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Trypanosoma cruzi pyruvate kinase 2, putative 0.0027 0.0057 0.0147
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0062 0.0287 0.0742
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0117 0.0261
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0074 0.0364 0.0493
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0022 0.0026 0.0061
Onchocerca volvulus 0.0112 0.0612 0.1717
Trypanosoma cruzi C-8 sterol isomerase, putative 0.042 0.2615 0.7337
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0036 0.0115 0.0155
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0022 0.0026 0.0135
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0064 0.0296 0.0766
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0518
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0064 0.0296 0.0766
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0059 0.0264 0.0677
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0157 0.0212
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.008 0.0404 0.1073
Echinococcus multilocularis adam 17 protease 0.074 0.4697 0.6359
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Brugia malayi cytochrome P450 0.0149 0.0853 0.1831
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0119 0.0266
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0059 0.008
Schistosoma mansoni polycystin 1-related 0.0038 0.0132 0.0264
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0112 0.0609 0.0824
Echinococcus multilocularis transient receptor potential cation channel 0.0042 0.0153 0.0208
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1154 0.7386 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0623 0.1738
Mycobacterium ulcerans DNA gyrase subunit B 0.0153 0.0877 0.4496
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.0187 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0058 0.0257 0.0552
Plasmodium vivax multidomain scavenger receptor, putative 0.0038 0.0132 0.0358
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0187 0.0374
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0364 0.1009
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0064 0.0296 0.0766
Echinococcus multilocularis short transient receptor potential channel 6 0.0042 0.0153 0.0208
Echinococcus multilocularis muscleblind protein 1 0.0312 0.1911 0.2587
Mycobacterium ulcerans transcriptional regulatory protein 0.0074 0.0364 0.1866
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.0116 0.0635 0.0635
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0051
Schistosoma mansoni 6-phosphofructokinase 0.0088 0.0452 0.0903
Chlamydia trachomatis DNA gyrase subunit B 0.0153 0.0877 0.4421
Schistosoma mansoni multidrug resistance protein 0.0036 0.0117 0.0234
Echinococcus granulosus glycine receptor subunit beta 0.0069 0.0328 0.0444
Echinococcus granulosus calcium activated potassium channel 0.0043 0.0159 0.0215
Schistosoma mansoni hypothetical protein 0.0209 0.1241 0.2481
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.007 0.0128
Leishmania major acetyl-CoA carboxylase, putative 0.0163 0.0944 0.2642
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0026 0.0061
Plasmodium vivax multidrug resistance protein 1, putative 0.0036 0.0117 0.0316
Echinococcus granulosus hypothetical protein 0.0042 0.0153 0.0208
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1241 0.1681
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0022 0.0025 0.0056
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0031 0.0082 0.0218
Echinococcus granulosus g protein coupled receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Plasmodium falciparum esterase, putative 0.008 0.0404 0.1123
Trypanosoma cruzi acetyl-CoA carboxylase 0.0101 0.054 0.1504
Echinococcus granulosus neural cadherin 0.0018 0.0003 0.0003
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0046 0.0184 0.0503
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0024 0.0036 0.0089
Plasmodium falciparum DNA topoisomerase 2 0.0069 0.0329 0.0913
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0149 0.0853 0.4373
Giardia lamblia PHD finger protein 15 0.0088 0.0456 0.1275
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0149 0.0853 0.2383
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.008
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0074 0.0364 0.0727
Schistosoma mansoni cell polarity protein 0.0018 0.0003 0.0005
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0024 0.0036 0.0049
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0058 0.0257 0.0348
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0117 0.0158
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0465 0.2904 0.3931
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.008 0.0109
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0058 0.0257 0.0348
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0635 0.1269
Echinococcus granulosus protein jagged 2 0.0018 0.0003 0.0003
Brugia malayi Cation transporter family protein 0.0069 0.0328 0.0705
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.013 0.0176
Loa Loa (eye worm) hypothetical protein 0.0074 0.0364 0.0364
Schistosoma mansoni biogenic amine (5HT) receptor 0.0348 0.2145 0.4288
Loa Loa (eye worm) hypothetical protein 0.0348 0.2145 0.2145
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0117 0.0261
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0149 0.0853 0.2342
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0149 0.0853 0.2342
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0257 0.0348
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Echinococcus multilocularis neurogenic locus notch protein 4 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0033 0.0095 0.0268
Onchocerca volvulus Bile acid receptor homolog 0.0058 0.0257 0.0721
Schistosoma mansoni ap endonuclease 0.0031 0.0081 0.0162
Echinococcus multilocularis transfer RNA-Gly 0.0042 0.0153 0.0208
Loa Loa (eye worm) hypothetical protein 0.0276 0.1677 0.1677
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0149 0.0853 0.4373
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0074 0.0364 0.0727
Schistosoma mansoni transient receptor potential channel 0.0042 0.0153 0.0307
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0047 0.0187 0.0253
Echinococcus granulosus pyruvate kinase 0.0027 0.0057 0.0077
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0042 0.0153 0.0307
Echinococcus multilocularis conserved hypothetical protein 0.0787 0.5003 0.6773
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Echinococcus multilocularis pyruvate kinase 0.0027 0.0057 0.0077
Schistosoma mansoni opsin-like receptor 0.0209 0.1241 0.2481
Entamoeba histolytica P-glycoprotein-2 0.0036 0.0117 0.0317
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0069 0.0329 0.0446
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus sodium channel protein 0.0042 0.0153 0.0208
Echinococcus granulosus protein jagged 1 0.0018 0.0003 0.0003
Schistosoma mansoni notch 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.0197
Schistosoma mansoni alpha-glucosidase 0.0228 0.1364 0.2726
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0209 0.1241 0.1681
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) glutathione reductase 0.0038 0.013 0.013
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.01 0.0531 0.1061
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0047 0.0187 0.0835
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0046 0.0063
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0129 0.0719 0.1438
Brugia malayi GCC2 and GCC3 family protein 0.0018 0.0003 0.0005
Onchocerca volvulus 0.0018 0.0003 0.0007
Brugia malayi RNA binding protein 0.0155 0.0893 0.1918
Trypanosoma cruzi protein kinase A regulatory subunit 0.0074 0.0364 0.1009
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0088 0.0452 0.1207
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0566 0.3562 1
Onchocerca volvulus 0.0019 0.0005 0.0013
Plasmodium falciparum lysophospholipase, putative 0.008 0.0404 0.1123
Echinococcus multilocularis voltage gated potassium channel 0.0164 0.0952 0.1289
Mycobacterium ulcerans hypothetical protein 0.0074 0.0364 0.1866
Echinococcus multilocularis transient receptor potential cation channel 0.0042 0.0153 0.0208
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0267 0.0361
Schistosoma mansoni voltage-gated potassium channel 0.0164 0.0952 0.1903
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0022 0.0026 0.0007
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0089 0.0463 0.0626
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0069 0.0328 0.0444
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0059 0.0118
Echinococcus granulosus lipoxygenase domain containing protein 0.0038 0.0132 0.0179
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0057
Entamoeba histolytica acyl-coA synthetase, putative 0.0022 0.0024 0.0055
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0209 0.1241 0.2481
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Loa Loa (eye worm) hypothetical protein 0.0276 0.1677 0.1677
Leishmania major monoglyceride lipase, putative 0.008 0.0404 0.1123
Brugia malayi multidrug resistance protein 3 0.0036 0.0117 0.0251
Brugia malayi hypothetical protein 0.0445 0.2774 0.596
Loa Loa (eye worm) neuropeptide F receptor 0.0209 0.1241 0.1241
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0187
Echinococcus multilocularis inositol monophosphatase 1 0.0114 0.0623 0.0843
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.035 0.0699
Plasmodium falciparum transporter, putative 0.0047 0.0187 0.0512
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0074 0.0364 0.0493
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0122
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0064 0.0296 0.0824
Brugia malayi Glycosyl hydrolases family 31 protein 0.0022 0.0025 0.0053
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0049 0.02 0.0495
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0036 0.0117 0.0322
Schistosoma mansoni loxhd1 0.0038 0.0132 0.0264
Schistosoma mansoni nck2/grb4 0.0021 0.0019 0.0037
Trypanosoma brucei cAMP binding protein, putative 0.0074 0.0364 0.0959
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0069 0.0188
Mycobacterium tuberculosis Conserved protein 0.0036 0.0119 0.0269
Brugia malayi Probable DNA topoisomerase II 0.0069 0.0329 0.0707
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.008 0.0404 0.1073
Schistosoma mansoni histamine h1 receptor 0.0209 0.1241 0.2481
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0022 0.0026 0.0061
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0542 0.3405 0.461
Brugia malayi isocitrate dehydrogenase 0.0034 0.0107 0.0229
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0042 0.0153 0.0208
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0163 0.0944 0.1279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0307 0.0613
Echinococcus multilocularis geminin 0.0363 0.2246 0.3041
Onchocerca volvulus 0.0038 0.0132 0.037
Loa Loa (eye worm) hypothetical protein 0.0036 0.0119 0.0119
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Brugia malayi TAR-binding protein 0.0155 0.0893 0.1918
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0018 0.0003 0.0005
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0062 0.0287 0.0742
Schistosoma mansoni coup transcription factor 0.0058 0.0257 0.0514
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0059 0.0127
Echinococcus granulosus ecdysone induced protein 78C 0.0058 0.0257 0.0348
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.038 0.0515
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0088
Leishmania major mitochondrial DNA polymerase beta 0.0325 0.1999 0.5606
Echinococcus granulosus muscleblind protein 0.0312 0.1911 0.2587
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0062 0.0287 0.0793
Trichomonas vaginalis phosphofructokinase, putative 0.0024 0.0036 0.0033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1241 0.2481
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0257 0.0348
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0107 0.0229
Onchocerca volvulus 0.0047 0.0187 0.0525
Brugia malayi RE15519p 0.0209 0.1241 0.2667
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0117 0.0261
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0121 0.0672 0.1875
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0048 0.0197 0.0197
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0364 0.1015
Loa Loa (eye worm) DR-78 0.0027 0.0059 0.0059
Echinococcus granulosus glycine receptor subunit beta 0.0069 0.0328 0.0444
Echinococcus granulosus glycine receptor subunit alpha 1 0.0069 0.0328 0.0444
Trypanosoma cruzi cAMP response protein 1, putative 0.0074 0.0364 0.1009
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.051 0.1375
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0069 0.0329 0.0925
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0119 0.0321
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0676 0.3465
Echinococcus granulosus transient receptor potential cation channel 0.0042 0.0153 0.0208
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0058 0.0257 0.0514
Onchocerca volvulus Neuropeptide F receptor homolog 0.0209 0.1241 0.3485
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.2269
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0062 0.0287 0.0744
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Mycobacterium tuberculosis Conserved protein 0.0036 0.0119 0.0269
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.1393 0.387
Echinococcus granulosus epidermal growth factor receptor 0.0343 0.2115 0.2864
Brugia malayi neuropeptide F receptor 0.0209 0.1241 0.2667
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0204 0.1212 0.1641
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0149 0.0853 0.4373
Schistosoma mansoni thyroid hormone receptor 0.0262 0.1587 0.3172
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0058 0.0263 0.0675
Echinococcus multilocularis expressed conserved protein 0.0075 0.0369 0.05
Leishmania major lanosterol synthase, putative 0.0052 0.0224 0.0616
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0566 0.3562 1
Mycobacterium ulcerans lysophospholipase 0.008 0.0404 0.2073
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0058 0.0257 0.0348
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0209 0.1241 0.1241
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0531 0.0719
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0074 0.0364 0.0493
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Schistosoma mansoni hypothetical protein 0.0204 0.1212 0.2423
Trichomonas vaginalis inositol monophosphatase, putative 0.0114 0.0623 0.1691
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0257 0.0552
Schistosoma mansoni hypothetical protein 0.0038 0.0132 0.0264
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.007 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0418 0.0835
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0042 0.0153 0.0208
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0024 0.0036 0.0032
Schistosoma mansoni amine GPCR 0.0209 0.1241 0.2481
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.178 0.4945
Loa Loa (eye worm) hypothetical protein 0.0036 0.0117 0.0117
Brugia malayi hypothetical protein 0.0027 0.0059 0.0127
Plasmodium falciparum amino acid transporter, putative 0.0047 0.0187 0.0512
Trichomonas vaginalis adenylate cyclase type, putative 0.0049 0.02 0.0495
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0074 0.0364 0.0959
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0042 0.0153 0.0364
Echinococcus granulosus tissue type plasminogen activator 0.0019 0.0005 0.0006
Loa Loa (eye worm) Notch2 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0019
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0566 0.3562 1
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0187
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0024 0.0036 0.0036
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0164 0.0952 0.1289
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0082 0.0082
Trypanosoma cruzi cAMP binding protein, putative 0.0074 0.0364 0.1009
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0049 0.02 0.0495
Brugia malayi intermediate filament protein 0.0031 0.0082 0.0177
Leishmania major hypothetical protein, conserved 0.0028 0.0068 0.0177
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0021 0.0019 0.0019
Trichomonas vaginalis maltase-glucoamylase, putative 0.0059 0.0264 0.0677
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0318 0.1949 1
Loa Loa (eye worm) hypothetical protein 0.0445 0.2774 0.2774
Loa Loa (eye worm) TAR-binding protein 0.0155 0.0893 0.0893
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0042 0.0153 0.0208
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Echinococcus multilocularis PHD finger protein rhinoceros 0.0088 0.0456 0.0618
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0154 0.0884 0.2429
Loa Loa (eye worm) TK protein kinase 0.0049 0.02 0.02
Echinococcus multilocularis lipoxygenase domain containing protein 0.0038 0.0132 0.0179
Brugia malayi hypothetical protein 0.0029 0.0069 0.0149
Echinococcus multilocularis short transient receptor potential channel 6 0.0042 0.0153 0.0208
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0074 0.0364 0.0959
Echinococcus granulosus slit 2 protein 0.0018 0.0003 0.0003
Echinococcus multilocularis potassium large conductance calcium activated 0.0042 0.0153 0.0208
Echinococcus granulosus peptidase Clp S14 family 0.0058 0.0263 0.0356
Loa Loa (eye worm) hypothetical protein 0.0074 0.0362 0.0362
Echinococcus granulosus tar DNA binding protein 0.0155 0.0893 0.1209
Onchocerca volvulus 0.0024 0.0036 0.0101
Brugia malayi olfactory channel protein osm-9 0.0042 0.0153 0.033
Trypanosoma cruzi protein farnesyltransferase, putative 0.0064 0.0296 0.0818
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0031 0.0081 0.0215
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0531 0.114
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0119 0.0269
Loa Loa (eye worm) hypothetical protein 0.0151 0.0866 0.0866
Schistosoma mansoni zinc finger protein 0.0021 0.0022 0.0043
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0163 0.0944 0.1279
Leishmania major hypothetical protein, conserved 0.0074 0.0364 0.1009
Echinococcus granulosus RUN 0.0038 0.0132 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Schistosoma mansoni voltage-gated potassium channel 0.0164 0.0952 0.1903
Echinococcus multilocularis tissue type plasminogen activator 0.0019 0.0005 0.0006
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0149 0.0853 0.4373
Plasmodium falciparum LCCL domain-containing protein 0.0038 0.0132 0.0358
Entamoeba histolytica P-glycoprotein-1 0.0036 0.0117 0.0317
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Echinococcus granulosus sodium leak channel non selective protein 0.0042 0.0153 0.0208
Echinococcus multilocularis Tolloid protein 1 0.0048 0.0197 0.0267
Schistosoma mansoni hypothetical protein 0.0074 0.0364 0.0727
Schistosoma mansoni neuropeptide receptor 0.0209 0.1241 0.2481
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0149 0.0853 0.4373
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0083 0.022
Brugia malayi hypothetical protein 0.003 0.008 0.0172
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0117 0.0158
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0149 0.0853 0.4373
Entamoeba histolytica P-glycoprotein-2, putative 0.0036 0.0117 0.0317
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0042 0.0153 0.033
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0074 0.0364 0.0961
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0058 0.0257 0.0348
Echinococcus granulosus tm gpcr rhodopsin 0.0209 0.1241 0.1681
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0064 0.0296 0.0818
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0036 0.0117 0.0316
Loa Loa (eye worm) hypothetical protein 0.0033 0.0097 0.0097
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0082 0.0177
Toxoplasma gondii pyruvate carboxylase 0.0062 0.0287 0.0799
Schistosoma mansoni multidrug resistance protein 0.0036 0.0117 0.0234
Plasmodium falciparum phd finger protein, putative 0.0088 0.0456 0.127
Schistosoma mansoni hypothetical protein 0.0467 0.2918 0.5831
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0042 0.0153 0.0307
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0209 0.1241 0.1681
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0117 0.0158
Brugia malayi G-protein coupled receptor 0.0209 0.1241 0.2667
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0041 0.0082
Loa Loa (eye worm) hypothetical protein 0.0089 0.0463 0.0463
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0116 0.0635 0.086
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0325 0.1999 0.5606
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0152 0.0874 0.1183
Echinococcus granulosus G protein coupled receptor 139 0.0209 0.1241 0.1681
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0028 0.0063 0.0167
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0026 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0264 0.073
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0042 0.0153 0.0307
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0546 0.3436 0.6868
Schistosoma mansoni notch 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Plasmodium vivax RNA helicase-1, putative 0.0566 0.3562 1
Echinococcus granulosus hypothetical protein 0.0996 0.6362 0.8613
Schistosoma mansoni tar DNA-binding protein 0.0155 0.0893 0.1785
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0042 0.0153 0.033
Schistosoma mansoni tyrosine kinase 0.0186 0.1091 0.2181
Loa Loa (eye worm) cytochrome P450 0.0149 0.0853 0.0853
Onchocerca volvulus 0.0209 0.1241 0.3485
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.0635 0.1725
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0209 0.1241 0.1681
Schistosoma mansoni tar DNA-binding protein 0.0155 0.0893 0.1785
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0062 0.0284 0.0735
Echinococcus granulosus hyperpolarization activated cyclic 0.0116 0.0635 0.086
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus multilocularis microtubule associated protein 2 0.0787 0.5003 0.6773
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0106 0.0574 0.1612
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0022 0.0026 0.003
Echinococcus multilocularis epidermal growth factor receptor 0.0186 0.1091 0.1477
Echinococcus multilocularis multidrug resistance protein 1 0.0025 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.0082 0.0418 0.0418
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0068 0.0068
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0049 0.02 0.0495
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Echinococcus multilocularis c src tyrosine kinase 0.0026 0.0051 0.0068
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0062 0.0287 0.1472
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0153 0.0877 0.2383
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0062 0.0287 0.0744
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0264 0.0677
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0116 0.0635 0.1725
Echinococcus multilocularis transient receptor potential cation channel 0.0042 0.0153 0.0208
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0021 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.008
Toxoplasma gondii hypothetical protein 0.0042 0.0153 0.0424
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0676 0.135
Trichomonas vaginalis valacyclovir hydrolase, putative 0.008 0.0404 0.1073
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0049 0.02 0.0495
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0042 0.0153 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0031 0.0081 0.0221
Echinococcus granulosus allatostatin A receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis NCK adaptor protein 0.0021 0.0019 0.0025
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0042 0.0153 0.0424
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0157 0.0313
Loa Loa (eye worm) hypothetical protein 0.0036 0.0115 0.0115
Echinococcus multilocularis multidrug resistance protein 1 0.0036 0.0117 0.0158
Onchocerca volvulus 0.0074 0.0364 0.1021
Schistosoma mansoni inositol monophosphatase 0.0114 0.0623 0.1245
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus g protein coupled receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) pyruvate kinase 0.0027 0.0057 0.0057
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0042 0.0153 0.0307
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0276 0.1677 0.3351
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0024 0.0036 0.0049
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0623 0.1691
Mycobacterium leprae putative cytochrome p450 0.0149 0.0853 0.982
Onchocerca volvulus Serine\/threonine kinase homolog 0.0152 0.0874 0.2453
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0138 0.0277
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0049 0.02 0.027
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0157 0.0433
Echinococcus granulosus 6 phosphofructokinase 0.0088 0.0452 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Echinococcus multilocularis lamin 0.0031 0.0082 0.0112
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0069 0.0182
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0149 0.0853 0.4373
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.2269
Loa Loa (eye worm) pyruvate kinase-PB 0.0019 0.0004 0.0004
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0119 0.0266
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0074 0.0364 0.1009
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0049 0.02 0.0495
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.0059 0.0127
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0022 0.0025 0.0057
Echinococcus granulosus tyrosine protein kinase Blk 0.0049 0.02 0.027
Brugia malayi Tachykinin-like peptides receptor 99D 0.0209 0.1241 0.2667
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1241 0.1681
Onchocerca volvulus 0.0276 0.1677 0.4707
Toxoplasma gondii hypothetical protein 0.0042 0.0153 0.0424
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0264 0.0677
Schistosoma mansoni two-pore calcium channel 0.0042 0.0153 0.0307
Onchocerca volvulus Alhambra homolog 0.0088 0.0456 0.1281
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0028 0.0068 0.0183
Echinococcus granulosus Polycystic kidney disease protein 0.0038 0.0132 0.0179
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0048 0.0197 0.0424
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0003 0.0005
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.1209
Loa Loa (eye worm) voltage-gated calcium channel 0.0042 0.0153 0.0153
Schistosoma mansoni pyruvate kinase 0.0027 0.0057 0.0114
Loa Loa (eye worm) jmjC domain-containing protein 0.0182 0.1068 0.1068
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0058 0.0257 0.0552
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Echinococcus granulosus cpg binding protein 0.0037 0.012 0.0162
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0209 0.1241 0.1681
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0028 0.0068 0.0135
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Toxoplasma gondii transporter, cation channel family protein 0.0042 0.0153 0.0424
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0059 0.0267 0.0361
Schistosoma mansoni tyrosine kinase 0.0181 0.1059 0.2117
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0312 0.1911 0.1911
Schistosoma mansoni amine GPCR 0.0209 0.1241 0.2481
Echinococcus granulosus g protein coupled receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.008 0.0404 0.4507
Echinococcus multilocularis survival motor neuron protein 1 0.0422 0.2627 0.3556
Brugia malayi Doublecortin family protein 0.0038 0.0132 0.0283
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0107 0.0287
Onchocerca volvulus Pyruvate kinase homolog 0.0027 0.0057 0.016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0119 0.0237
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Schistosoma mansoni cpg binding protein 0.0033 0.0095 0.0191
Loa Loa (eye worm) hypothetical protein 0.0422 0.2627 0.2627
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0089 0.0463 0.52
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.013 0.03
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0149 0.0853 0.4373
Onchocerca volvulus 0.0036 0.0119 0.0334
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0318 0.1949 0.5442
Schistosoma mansoni adenoreceptor 0.0209 0.1241 0.2481
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.0251 0.1516 0.1516
Schistosoma mansoni hypothetical protein 0.0363 0.2246 0.449
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0088 0.0456 0.0912
Loa Loa (eye worm) hypothetical protein 0.0215 0.1279 0.1279
Trichomonas vaginalis phosphofructokinase, putative 0.0024 0.0036 0.0033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0062 0.0288 0.0576
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0061 0.0278 0.0598
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0209 0.1241 0.2481
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0047 0.0187 0.0253
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0024 0.0036 0.0088
Chlamydia trachomatis endonuclease IV 0.0062 0.0284 0.1339
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0016 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0042 0.0153 0.0208
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0187 0.0374
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0074 0.0364 0.0493
Echinococcus granulosus potassium voltage gated channel protein 0.0042 0.0153 0.0208
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Echinococcus granulosus cGMP dependent protein kinase 1 0.0075 0.0369 0.05
Leishmania major cytochrome p450-like protein 0.0149 0.0853 0.2383
Echinococcus multilocularis lamin dm0 0.0031 0.0082 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0149 0.0853 0.2342
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0051
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0179 0.1047 0.1417
Schistosoma mansoni transient receptor potential channel 0.0042 0.0153 0.0307
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.0059 0.008
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0019 0.004
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0149 0.0853 0.2342
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0042 0.0153 0.0418
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.081 0.5147 0.6968
Mycobacterium ulcerans lipase LipD 0.0036 0.0119 0.0609
Schistosoma mansoni opsin-like receptor 0.0209 0.1241 0.2481
Treponema pallidum catabolite gene activator 0.0074 0.0364 0.0929
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0064 0.0296 0.0296
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0149 0.0853 0.2342
Echinococcus multilocularis thyroid hormone receptor alpha 0.0262 0.1587 0.2148
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0031 0.0081 0.0215
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0024 0.0036 0.0072
Loa Loa (eye worm) hypothetical protein 0.0164 0.0952 0.0952
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0022 0.0026 0.0036
Echinococcus granulosus short transient receptor potential channel 6 0.0042 0.0153 0.0208
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0267 0.0361
Echinococcus granulosus neutral alpha glucosidase AB 0.0059 0.0264 0.0358
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0064 0.0296 0.0819
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0364 0.0959
Loa Loa (eye worm) hypothetical protein 0.0055 0.0239 0.0239
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0076 0.0378 0.0755
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Plasmodium falciparum eukaryotic initiation factor 4A 0.0566 0.3562 1
Echinococcus multilocularis notch 0.0018 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0209 0.1241 0.1681
Schistosoma mansoni pyruvate carboxylase 0.0062 0.0287 0.0573
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0289 0.1762 0.2386
Brugia malayi conserved hypotetical protein 0.0027 0.0059 0.0127
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0209 0.1241 0.1681
Echinococcus multilocularis phd:f box containing protein 0.0028 0.0068 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0149 0.0853 0.2342
Brugia malayi Delta serrate ligand family protein 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0215 0.1283 0.1283
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0566 0.3562 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0364 0.0961
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0074 0.0364 0.1015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0149 0.0853 0.4373
Schistosoma mansoni microtubule-associated protein tau 0.0787 0.5003 1
Echinococcus granulosus insulin receptor 0.0112 0.0609 0.0824
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Entamoeba histolytica protein kinase, putative 0.0038 0.0131 0.0355
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0402
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0074 0.0362 0.0491
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0074 0.0364 0.0959
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0107 0.0287
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0068 0.0068
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0059 0.0267 0.0361
Echinococcus granulosus PHD finger protein rhinoceros 0.0088 0.0456 0.0618
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0069 0.0328 0.0656
Toxoplasma gondii hypothetical protein 0.0052 0.0224 0.0621
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0049 0.02 0.0495
Trichomonas vaginalis CAMK family protein kinase 0.0076 0.0374 0.0988
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0024 0.0036 0.0032
Echinococcus granulosus neuropeptide Y receptor 0.0209 0.1241 0.1681
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0119 0.0269
Treponema pallidum sodium- and chloride- dependent transporter 0.0276 0.1677 0.4653
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.013 0.0176
Schistosoma mansoni 60S ribosomal protein L21 0.009 0.0471 0.0941
Echinococcus multilocularis lysosomal alpha glucosidase 0.0265 0.1603 0.2171
Onchocerca volvulus Neurogenic locus notch homolog 0.0018 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0155 0.0893 0.1785
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0149 0.0853 0.2383
Echinococcus multilocularis tyrosine protein kinase Srms 0.0049 0.02 0.027
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0058 0.0258 0.0661
Echinococcus multilocularis growth factor receptor bound protein 2 0.0021 0.0019 0.0025
Plasmodium vivax pyruvate kinase, putative 0.0027 0.0057 0.0147
Onchocerca volvulus 0.0094 0.0494 0.1387
Echinococcus granulosus dro:myosuppressin receptor 0.0209 0.1241 0.1681
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0209 0.1241 0.1681
Brugia malayi ecdysteroid receptor 0.0058 0.0257 0.0552
Trichomonas vaginalis pyruvate kinase, putative 0.0027 0.0057 0.0092
Treponema pallidum ATP-dependent RNA helicase 0.0566 0.3562 1
Echinococcus multilocularis G protein coupled receptor 139 0.0209 0.1241 0.1681
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0163 0.0944 0.2646
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0058 0.0257 0.0552
Echinococcus multilocularis serotonin receptor 0.0348 0.2145 0.2904
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0074 0.0362 0.0724
Loa Loa (eye worm) SRC-1 0.0059 0.0267 0.0267
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.035 0.2156 0.4309
Echinococcus multilocularis musashi 0.0031 0.0082 0.0112
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0117 0.0261
Brugia malayi Transient-receptor-potential like protein 0.0042 0.0153 0.033
Loa Loa (eye worm) hypothetical protein 0.0106 0.0574 0.0574
Echinococcus multilocularis conserved hypothetical protein 0.0042 0.0153 0.0208
Schistosoma mansoni alpha-glucosidase 0.0228 0.1364 0.2726
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0021 0.0019 0.0037
Echinococcus granulosus transient receptor potential cation channel 0.0042 0.0153 0.0208
Onchocerca volvulus 0.0209 0.1241 0.3485
Echinococcus multilocularis sodium channel protein 0.0042 0.0153 0.0208
Echinococcus granulosus TRP transient receptor potential channel 0.0042 0.0153 0.0208
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0051
Loa Loa (eye worm) hypothetical protein 0.0546 0.3436 0.3436
Schistosoma mansoni septate junction protein 0.0018 0.0003 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0058 0.0257 0.0348
Schistosoma mansoni nuclear receptor 0.0027 0.0059 0.0118
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0047 0.0187 0.0253
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.013 0.0352
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0209 0.1241 0.1681
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0058 0.0263 0.2831
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.0059 0.0059
Mycobacterium ulcerans hypothetical protein 0.0036 0.0119 0.0609
Loa Loa (eye worm) hypothetical protein 0.0681 0.4314 0.4314
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0566 0.3562 0.4822
Brugia malayi Serotonin receptor 0.0734 0.4655 1
Schistosoma mansoni 6-phosphofructokinase 0.0088 0.0452 0.0903
Loa Loa (eye worm) hypothetical protein 0.0036 0.0119 0.0119
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0157 0.0427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0245 0.0676
Brugia malayi Bromodomain containing protein 0.0038 0.0131 0.0281
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0149 0.0853 0.4373
Brugia malayi PHD-finger family protein 0.0033 0.0095 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0149 0.0853 0.2342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0089 0.0463 0.1293
Leishmania major farnesyltransferase beta subunit 0.0064 0.0296 0.0818
Echinococcus multilocularis G-protein coupled receptor, putative 0.0209 0.1241 0.1681
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0022 0.0024 0.0122
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0059 0.008
Loa Loa (eye worm) calcium channel 0.0042 0.0153 0.0153
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.038 0.0515
Echinococcus multilocularis tyrosine protein kinase Abl 0.0026 0.0051 0.0068
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0031 0.0081 0.011
Brugia malayi Tyrosine-protein kinase abl-1 0.0026 0.0051 0.0109
Trypanosoma cruzi cytochrome P450, putative 0.0293 0.1789 0.5016
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0059 0.0264 0.0731
Echinococcus multilocularis voltage dependent calcium channel 0.0042 0.0153 0.0208
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0059 0.0127
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.0059 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0404 0.1073
Brugia malayi glutathione reductase 0.0038 0.013 0.0279
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.008 0.016
Mycobacterium ulcerans DNA gyrase subunit A 0.0318 0.1949 1
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0566 0.3562 1
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.0566 0.3562 0.3562
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0024 0.0036 0.0072
Echinococcus multilocularis transient receptor potential gamma protein 0.0042 0.0153 0.0208
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0027 0.0057 0.0094
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0022 0.0026 0.0135
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0074 0.0364 0.0493
Trypanosoma brucei acetyl-CoA carboxylase 0.0163 0.0944 0.26
Echinococcus multilocularis fat cadherin tumor suppressor 0.0018 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase type, putative 0.0049 0.02 0.0495
Entamoeba histolytica hypothetical protein 0.0077 0.038 0.1057
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0069 0.0328 0.0656
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0179 0.1047 0.1417
Plasmodium falciparum thioredoxin reductase 0.0038 0.013 0.0352
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0059 0.0267 0.0361
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0026 0.0051 0.0101
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0024 0.0036 0.0049
Schistosoma mansoni ryanodine receptor related 0.0042 0.0153 0.0307
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Schistosoma mansoni peptidase Clp (S14 family) 0.0089 0.0463 0.0925
Echinococcus granulosus epidermal growth factor receptor 0.0186 0.1091 0.1477
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0267 0.0361
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0024 0.0036 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0149 0.0853 0.4373
Schistosoma mansoni intermediate filament proteins 0.0031 0.0082 0.0165
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0058 0.0257 0.0257
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0061 0.0278 0.0377
Plasmodium falciparum multidrug resistance protein 1 0.0036 0.0117 0.0316
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0118 0.0651 0.1817
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0064 0.0296 0.04
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0364 0.1015
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0042 0.0153 0.0208
Plasmodium vivax DNA gyrase subunit A, putative 0.0318 0.1949 0.5467
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0048 0.0197 0.0197
Schistosoma mansoni hypothetical protein 0.0049 0.02 0.0399
Echinococcus granulosus hyperpolarization activated cyclic 0.0116 0.0635 0.086
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0209 0.1241 0.1681
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0088
Onchocerca volvulus 0.0018 0.0003 0.0007
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0119 0.0269
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0074 0.0364 0.0727
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0032
Schistosoma mansoni tyrosine kinase 0.0112 0.0609 0.1217
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.0059 0.008
Leishmania major hypothetical protein, conserved 0.0029 0.0069 0.0182
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0042 0.0153 0.0418
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0264 0.073
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0209 0.1241 0.2481
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0069 0.0328 0.0444
Echinococcus multilocularis FTZ F1 alpha 0.0058 0.0257 0.0348
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0022 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0068
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0566 0.3562 0.4822
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.007 0.0189
Brugia malayi cation channel family protein 0.0042 0.0153 0.033
Echinococcus granulosus serotonin transporter 0.0276 0.1677 0.227
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0117 0.0261
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0024 0.0055
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Echinococcus granulosus potassium voltage gated channel protein 0.0042 0.0153 0.0208
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0307 0.0855
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0028 0.0068 0.0177
Brugia malayi Pyruvate kinase, muscle isozyme 0.0027 0.0057 0.0123
Echinococcus multilocularis lipoxygenase domain containing protein 0.0038 0.0132 0.0179
Leishmania major ATP-dependent phosphofructokinase 0.0088 0.0452 0.1257
Brugia malayi nuclear receptor NHR-88 0.0058 0.0257 0.0552
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0018 0.0003 0.0007
Echinococcus multilocularis neuropeptide FF receptor 2 0.0209 0.1241 0.1681
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0153 0.0877 0.4421
Toxoplasma gondii hypothetical protein 0.0047 0.0187 0.0518
Schistosoma mansoni alpha-1 adrenergic receptor 0.0209 0.1241 0.2481
Echinococcus granulosus biogenic amine 5HT receptor 0.0209 0.1241 0.1681
Leishmania major regulatory subunit of protein kinase a-like protein 0.0074 0.0364 0.1009
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0149 0.0853 0.2342
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0542 0.3405 0.7314
Echinococcus granulosus fibropellin Ia 0.0018 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0471 0.0941
Loa Loa (eye worm) hypothetical protein 0.0112 0.0612 0.0612
Loa Loa (eye worm) pyruvate kinase 0.0027 0.0057 0.0057
Echinococcus multilocularis voltage dependent calcium channel 0.0042 0.0153 0.0208
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0566 0.3562 0.4822
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0317 0.0883
Brugia malayi Glycosyl hydrolases family 31 protein 0.0265 0.1603 0.3444
Toxoplasma gondii DNA topoisomerase 2, putative 0.0069 0.0329 0.0918
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0209 0.1241 0.2667
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0187 0.0374
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0119 0.0609
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.0158 0.0907 0.0907
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Schistosoma mansoni neuropeptide receptor 0.0209 0.1241 0.2481
Schistosoma mansoni cpg binding protein 0.0037 0.012 0.024
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0149 0.0853 0.2342
Echinococcus multilocularis jumonji domain containing protein 0.0123 0.0681 0.0922
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0168 0.0227
Echinococcus granulosus somatostatin receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0107 0.0144
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0069 0.0328 0.0444
Trichomonas vaginalis DNA topoisomerase II, putative 0.0069 0.0329 0.0861
Trichomonas vaginalis pyruvate kinase, putative 0.0027 0.0057 0.0092
Loa Loa (eye worm) hypothetical protein 0.0036 0.0119 0.0119
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0026 0.0061
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0107 0.0213
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0119 0.0321
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0069 0.0328 0.0328
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0074 0.0364 0.0493
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0036 0.0117 0.0322
Echinococcus multilocularis tar DNA binding protein 0.0155 0.0893 0.1209
Echinococcus multilocularis laminin 0.0048 0.0197 0.0267
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0447 0.1197
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Echinococcus granulosus tyrosine kinase 0.0049 0.02 0.027
Onchocerca volvulus Slit protein homolog 0.0018 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0312 0.1911 0.1911
Onchocerca volvulus 0.0209 0.1241 0.3485
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0059 0.008
Mycobacterium ulcerans hypothetical protein 0.0074 0.0364 0.1866
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0122
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0074 0.0364 0.0781
Brugia malayi Cytochrome P450 family protein 0.0293 0.1789 0.3843
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0116 0.0635 0.086
Loa Loa (eye worm) norepinephrine transporter 0.0276 0.1677 0.1677
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0107 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.0076 0.0374 0.0988
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0024 0.0054
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0022 0.0024 0.0122
Echinococcus multilocularis ryanodine receptor 44f 0.0042 0.0153 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Brugia malayi phosphofructokinase 0.0088 0.0452 0.097
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0074 0.0364 0.0493
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0157 0.0374
Plasmodium falciparum DNA gyrase subunit A 0.0318 0.1949 0.5467
Schistosoma mansoni cpg binding protein 0.0037 0.012 0.024
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0456 0.1275
Loa Loa (eye worm) notch protein 0.0018 0.0003 0.0003
Brugia malayi sulfakinin receptor protein 0.0209 0.1241 0.2667
Trypanosoma cruzi lanosterol synthase, putative 0.007 0.0336 0.0931
Echinococcus multilocularis ATP binding cassette sub family B 0.0036 0.0115 0.0155
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0069 0.0182
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0293 0.1789 0.9177
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0082 0.0082
Schistosoma mansoni inositol monophosphatase 0.0114 0.0623 0.1245
Brugia malayi G protein-coupled receptor 0.0209 0.1241 0.2667
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0149 0.0853 0.2342
Brugia malayi Cyclic-nucleotide gated cation channel 0.0116 0.0635 0.1364
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0149 0.0853 0.4373
Brugia malayi jmjC domain containing protein 0.0111 0.0602 0.1292
Schistosoma mansoni hypothetical protein 0.0209 0.1241 0.2481
Echinococcus granulosus neuropeptide FF receptor 2 0.0209 0.1241 0.1681
Onchocerca volvulus Pyruvate kinase homolog 0.0027 0.0057 0.016
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0069 0.0328 0.0444
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0282 0.0382
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0024 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Schistosoma mansoni hypothetical protein 0.0077 0.038 0.076
Onchocerca volvulus 0.0031 0.0082 0.0231
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0209 0.1241 0.1681
Treponema pallidum cyclic nucleotide binding protein 0.0074 0.0364 0.0929
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0116 0.0635 0.0635
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0531 0.0719
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0058 0.0257 0.0348
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0675 0.427 0.427
Schistosoma mansoni lipoxygenase 0.0179 0.1047 0.2092
Echinococcus multilocularis zinc finger protein 0.0021 0.0022 0.0029
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0149 0.0853 0.4373
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0022 0.0026 0.003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0069 0.0328 0.0444
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0042 0.0153 0.0208
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0059 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0152 0.0874 0.2443
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0042 0.0153 0.033
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Giardia lamblia DNA topoisomerase II 0.0064 0.0298 0.083
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0074 0.0364 0.0727
Echinococcus multilocularis neuropeptide Y receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) hypothetical protein 0.0038 0.0132 0.0132
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0024 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0132 0.0132
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0264 0.0677
Schistosoma mansoni lipoxygenase 0.011 0.0597 0.1194
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.008 0.0404 0.1124
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0209 0.1241 0.1681
Toxoplasma gondii exonuclease III APE 0.0031 0.0081 0.0221
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0036 0.0117 0.0261
Trypanosoma cruzi DNA topoisomerase II, putative 0.0058 0.0258 0.0713
Onchocerca volvulus 0.0209 0.1241 0.3485
Echinococcus granulosus GPCR family 2 0.01 0.0531 0.0719
Brugia malayi nuclear hormone receptor 0.0247 0.149 0.3201
Echinococcus multilocularis hyperpolarization activated cyclic 0.0116 0.0635 0.086
Echinococcus granulosus cytochrome P450 2K1 0.0149 0.0853 0.1154
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0024 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0445 0.2774 0.2774
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0024 0.0054
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0116 0.0635 0.086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Brugia malayi Bromodomain containing protein 0.0091 0.0472 0.1013
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0074 0.0364 0.0727
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0531 0.0719
Brugia malayi G protein-coupled receptor F59B2.13 0.0209 0.1241 0.2667
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.007 0.0128
Schistosoma mansoni jumonji domain containing protein 0.0028 0.0068 0.0135
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0149 0.0853 0.2383
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.178 0.4991
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0089 0.0463 0.1287
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.051 0.5766
Onchocerca volvulus Putative cubilin 0.0018 0.0003 0.0007
Brugia malayi nuclear hormone receptor 0.0058 0.0257 0.0552
Onchocerca volvulus 0.0513 0.3219 0.9036
Loa Loa (eye worm) hypothetical protein 0.0315 0.1932 0.1932
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0047 0.0187 0.0402
Echinococcus granulosus laminin 0.0048 0.0197 0.0267
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0282 0.0382
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0088 0.0457 0.1277
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0042 0.0153 0.0208
Echinococcus granulosus disintegrin and metalloproteinase 0.0074 0.0362 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus neuropeptides capa receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis jumonji domain containing 1A 0.0028 0.0068 0.0092
Echinococcus granulosus eukaryotic initiation factor 4A 0.0566 0.3562 0.4822
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0157 0.0212
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0042 0.0153 0.0208
Schistosoma mansoni growth factor receptor-bound protein 0.0021 0.0019 0.0037
Plasmodium falciparum DNA gyrase subunit B 0.0153 0.0877 0.2451
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0062 0.0287 0.3118
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0149 0.0853 0.2342
Brugia malayi Furin-like cysteine rich region family protein 0.0343 0.2115 0.4543
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0364 0.1015
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0042 0.0153 0.0208
Schistosoma mansoni tyrosine kinase 0.0343 0.2115 0.4228
Echinococcus granulosus lysine specific demethylase 6a 0.0028 0.0068 0.0092
Mycobacterium leprae Probable pyruvate kinase PykA 0.0027 0.0057 0.0395
Echinococcus granulosus pyruvate kinase 0.0027 0.0057 0.0077
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0022 0.0026 0.003
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0149 0.0853 0.2342
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0058 0.0257 0.0552
Mycobacterium tuberculosis Probable reductase 0.0087 0.0447 0.1197
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0036 0.0088
Brugia malayi Egg laying defective protein 4 0.0075 0.0369 0.0793
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0024 0.0036 0.0088
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0566 0.3562 0.712
Schistosoma mansoni hypothetical protein 0.0088 0.0456 0.0912
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.0874 0.2401
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0074 0.0364 0.1009
Schistosoma mansoni hypothetical protein 0.01 0.0531 0.1061
Echinococcus granulosus potassium voltage gated channel protein 0.0042 0.0153 0.0208
Onchocerca volvulus 0.0038 0.0132 0.037
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.05 0.3134 0.8789
Brugia malayi Muscleblind-like protein 0.0312 0.1911 0.4104
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0209 0.1241 0.1241
Echinococcus granulosus inositol monophosphatase 1 0.0114 0.0623 0.0843
Schistosoma mansoni lozenge 0.0056 0.0245 0.049
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0088 0.0452 0.1257
Schistosoma mansoni smdr2 0.0036 0.0117 0.0234
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.0059 0.008
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0024 0.0036 0.0088
Trypanosoma brucei Flagellar Member 6 0.0074 0.0364 0.0959
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0059 0.0118
Trichomonas vaginalis abcb9, putative 0.0036 0.0117 0.0261
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Leishmania major hypothetical protein, conserved 0.0042 0.0153 0.0418
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0117 0.0261
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.0197
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0047 0.0187 0.0253
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Leishmania major hypothetical protein, conserved 0.0036 0.0119 0.0321
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.05 0.3134 0.8789
Echinococcus granulosus fmrfamide receptor 0.0209 0.1241 0.1681
Onchocerca volvulus 0.0445 0.2774 0.7789
Leishmania major hypothetical protein, unknown function 0.0074 0.0364 0.1009
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Leishmania major eukaryotic initiation factor 4a, putative 0.0566 0.3562 1
Schistosoma mansoni egf-like domain protein 0.0048 0.0197 0.0394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0058 0.0257 0.0257
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.0187 0.0253
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0069 0.0182
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0022 0.0025 0.0069
Schistosoma mansoni hypothetical protein 0.0042 0.0153 0.0307
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Loa Loa (eye worm) TK protein kinase 0.0038 0.0131 0.0131
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0058 0.0257 0.0348
Brugia malayi AF-10 protein 0.0029 0.007 0.015
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0289 0.1762 0.2386
Schistosoma mansoni multidrug resistance protein 0.0036 0.0117 0.0234
Onchocerca volvulus 0.0209 0.1241 0.3485
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Trypanosoma cruzi protein farnesyltransferase, putative 0.0064 0.0296 0.0818
Echinococcus multilocularis potassium voltage gated channel protein 0.0042 0.0153 0.0208
Echinococcus granulosus adam 0.0129 0.0719 0.0974
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0546 0.3436 0.3436
Loa Loa (eye worm) inositol-1 0.0114 0.0623 0.0623
Loa Loa (eye worm) RNA binding protein 0.0155 0.0893 0.0893
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0133 0.0745 0.1009
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0042 0.0153 0.033
Echinococcus multilocularis muscleblind protein 0.0312 0.1911 0.2587
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Schistosoma mansoni tyrosine kinase 0.0026 0.0051 0.0101
Loa Loa (eye worm) phosphofructokinase 0.0088 0.0452 0.0452
Toxoplasma gondii calcium binding egf domain-containing protein 0.0048 0.0197 0.0547
Brugia malayi MH2 domain containing protein 0.0244 0.1471 0.3159
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Chlamydia trachomatis DNA gyrase subunit A 0.0033 0.0097 0.0368
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.008 0.0404 0.1073
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus phd:f box containing protein 0.0028 0.0068 0.0092
Brugia malayi Disintegrin family protein 0.0074 0.0362 0.0778
Onchocerca volvulus 0.0027 0.0059 0.0166
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0003 0.0005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0042 0.0153 0.0208
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0028 0.0068 0.0122
Schistosoma mansoni amine GPCR 0.0776 0.4928 0.9851
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Schistosoma mansoni hypothetical protein 0.0363 0.2246 0.449
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0315 0.1932 0.1932
Schistosoma mansoni hypothetical protein 0.0019 0.0005 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0069 0.0182
Chlamydia trachomatis biotin carboxylase 0.0056 0.025 0.1162
Brugia malayi ion channel NompC 0.0042 0.0153 0.033
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.0187 0.0253
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.008
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0676 0.0915
Schistosoma mansoni lamin 0.0031 0.0082 0.0165
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0069 0.0329 0.0707
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0149 0.0853 0.4373
Loa Loa (eye worm) hypothetical protein 0.0036 0.0117 0.0117
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0042 0.0153 0.0431
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0267 0.0361
Schistosoma mansoni amine GPCR 0.0209 0.1241 0.2481
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Plasmodium falciparum JmjC domain-containing protein, putative 0.0028 0.0068 0.0177
Echinococcus granulosus neurogenic locus protein delta 0.0018 0.0003 0.0003
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0089
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0117 0.0261
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0157 0.0212
Trichomonas vaginalis phosphofructokinase, putative 0.0024 0.0036 0.0033
Echinococcus multilocularis insulin receptor 0.0112 0.0609 0.0824
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.074 0.4697 0.9389
Onchocerca volvulus Arrow homolog 0.0048 0.0197 0.0554
Mycobacterium leprae Possible transporter protein 0.0049 0.02 0.2083
Trypanosoma brucei DNA topoisomerase ii 0.0121 0.0672 0.1829
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0209 0.1241 0.2481
Loa Loa (eye worm) 6-phosphofructokinase 0.0088 0.0452 0.0452
Echinococcus multilocularis neuropeptide Y receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) jmjC domain-containing protein 0.0111 0.0602 0.0602
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.0187 0.0374
Plasmodium vivax 6-phosphofructokinase, putative 0.0024 0.0036 0.0088
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0064 0.0296 0.0766
Schistosoma mansoni tyrosine kinase 0.0181 0.1059 0.2117
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0042 0.0153 0.0307
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0069 0.0329 0.0707
Echinococcus multilocularis neuropeptide s receptor 0.0209 0.1241 0.1681
Trypanosoma brucei protein kinase A regulatory subunit 0.0074 0.0364 0.0959
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0119 0.0269
Trichomonas vaginalis sucrase-isomaltase, putative 0.0059 0.0264 0.0677
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0003 0.0003
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.008 0.016
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0257 0.0552
Echinococcus granulosus dnaJ subfamily B 0.0467 0.2918 0.395
Brugia malayi hypothetical protein 0.0027 0.0059 0.0127
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0315 0.1932 0.4149
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0059 0.008
Schistosoma mansoni tyrosine kinase 0.0059 0.0267 0.0534
Trypanosoma brucei polo-like protein kinase 0.0152 0.0874 0.2401
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0267 0.0361
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0062 0.0287 0.1355
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0209 0.1241 0.1241
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0447 0.1197
Echinococcus multilocularis sex peptide receptor 0.0209 0.1241 0.1681
Onchocerca volvulus 0.0047 0.0187 0.0525
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0059 0.0264 0.0735
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.0059 0.0127
Onchocerca volvulus 0.0058 0.0257 0.0721
Onchocerca volvulus 0.0209 0.1241 0.3485
Echinococcus multilocularis fmrfamide receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0064 0.0296 0.04
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0149 0.0853 0.4373
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Leishmania major eukaryotic initiation factor 4a, putative 0.0566 0.3562 1
Brugia malayi Trypsin family protein 0.0112 0.0612 0.1314
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0157 0.0374
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0059 0.0267 0.0361
Schistosoma mansoni acetyl-CoA carboxylase 0.0163 0.0944 0.1888
Loa Loa (eye worm) hypothetical protein 0.0062 0.0285 0.0285
Echinococcus multilocularis GPCR, family 2 0.01 0.0531 0.0719
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.0809 0.222
Schistosoma mansoni rab6-interacting 0.0038 0.0132 0.0264
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0058 0.0257 0.0257
Echinococcus granulosus 7tm_1 domain containing protein 0.0209 0.1241 0.1681
Echinococcus granulosus voltage dependent calcium channel 0.0042 0.0153 0.0208
Schistosoma mansoni biogenic amine receptor 0.0209 0.1241 0.2481
Giardia lamblia Kinase, PLK 0.0152 0.0874 0.2448
Brugia malayi hypothetical protein 0.0422 0.2627 0.5642
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0058 0.0257 0.0257
Echinococcus multilocularis voltage gated potassium channel 0.0042 0.0153 0.0208
Echinococcus multilocularis dnaJ subfamily B 0.0467 0.2918 0.395
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.0092 0.0125
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.008 0.0404 0.1073
Schistosoma mansoni biogenic amine receptor 0.0209 0.1241 0.2481
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Echinococcus multilocularis disintegrin and metalloproteinase 0.0074 0.0362 0.0491
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0095 0.0095
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0187 0.0374
Loa Loa (eye worm) hypothetical protein 0.0062 0.0284 0.0284
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0049 0.02 0.0495
Schistosoma mansoni hypothetical protein 0.0215 0.1283 0.2565
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.008 0.0172
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.178 0.4993
Loa Loa (eye worm) hypothetical protein 0.0036 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Echinococcus granulosus potassium voltage gated channel protein 0.0042 0.0153 0.0208
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0064 0.0296 0.0591
Leishmania major glycosyl hydrolase-like protein 0.0022 0.0025 0.0056
Echinococcus multilocularis tumor protein p63 0.0727 0.4609 0.624
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Brugia malayi N-terminal motif family protein 0.0251 0.1516 0.3258
Onchocerca volvulus 0.0209 0.1241 0.3485
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0042 0.0153 0.033
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0032
Mycobacterium ulcerans endonuclease IV 0.0062 0.0284 0.1456
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0058 0.0257 0.0348
Entamoeba histolytica P-glycoprotein-2 0.0036 0.0117 0.0317
Onchocerca volvulus 0.0074 0.0364 0.1021
Echinococcus multilocularis two pore calcium channel protein 1 0.0042 0.0153 0.0208
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0024 0.0036 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0049 0.02 0.0495
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0119 0.0269
Echinococcus multilocularis peptidase Clp (S14 family) 0.0058 0.0263 0.0356
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0307 0.0613
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0024 0.0036 0.009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0307 0.0415
Brugia malayi Cadherin domain containing protein 0.0018 0.0003 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0369 0.0738
Mycobacterium tuberculosis Conserved protein 0.0036 0.0119 0.0269
Brugia malayi jmjC domain containing protein 0.0028 0.0068 0.0145
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.018 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0149 0.0853 0.2342
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0447 0.1197
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0003 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Echinococcus granulosus jumonji domain containing 1A 0.0028 0.0068 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0058 0.0257 0.0552
Schistosoma mansoni adapter molecule crk 0.0021 0.0019 0.0037
Mycobacterium leprae Conserved hypothetical protein 0.0149 0.0853 0.982
Toxoplasma gondii calcium binding egf domain-containing protein 0.0048 0.0197 0.0547
Brugia malayi Pyruvate kinase, M2 isozyme 0.0027 0.0057 0.0123
Echinococcus multilocularis potassium voltage gated channel protein 0.0042 0.0153 0.0208
Trichomonas vaginalis phosphofructokinase, putative 0.0088 0.0452 0.1207
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0149 0.0853 0.4373
Echinococcus granulosus tyrosine protein kinase Lyn 0.006 0.0272 0.0369
Toxoplasma gondii cytochrome p450 superfamily protein 0.0149 0.0853 0.2388
Echinococcus granulosus serotonin receptor 0.0209 0.1241 0.1681
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0062 0.0285 0.0613
Echinococcus granulosus Tolloid protein 1 0.0048 0.0197 0.0267
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0074 0.0364 0.0727
Echinococcus granulosus potassium voltage gated channel protein 0.0042 0.0153 0.0208
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0157 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0114 0.0623 0.1739
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0364 0.0959
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0049 0.02 0.0495
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0031 0.0083 0.022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0116 0.0635 0.1269
Brugia malayi jmjC domain containing protein 0.0028 0.0068 0.0145
Brugia malayi angiogenesis inhibito 0.0055 0.0239 0.0514
Toxoplasma gondii transporter, cation channel family protein 0.0042 0.0153 0.0424
Brugia malayi hypothetical protein 0.0042 0.0153 0.033
Plasmodium vivax JmjC domain containing protein 0.0028 0.0068 0.0177
Onchocerca volvulus 0.0031 0.0082 0.0231
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0059 0.0166
Onchocerca volvulus 0.0209 0.1241 0.3485
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0074 0.0364 0.0493
Brugia malayi Inositol-1 0.0114 0.0623 0.1338
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0024 0.0036 0.0088
Brugia malayi PHD-finger family protein 0.0027 0.0056 0.0121
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0119 0.0119
Plasmodium vivax SET domain protein, putative 0.0065 0.0307 0.085
Echinococcus granulosus protein jagged 1 0.0018 0.0003 0.0003
Loa Loa (eye worm) TOPoisomerase family member 0.0069 0.0329 0.0329
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0058 0.0257 0.0552
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0042 0.0153 0.0307
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0112 0.0612 0.1223
Echinococcus multilocularis fibrillin 1 0.0048 0.0197 0.0267
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0074 0.0364 0.0961
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0116 0.0635 0.1269
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0676 0.1842
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0209 0.1241 0.1681
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0042 0.0153 0.033
Loa Loa (eye worm) hypothetical protein 0.0276 0.1677 0.1677
Echinococcus multilocularis 6 phosphofructokinase 0.0088 0.0452 0.0611
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0112 0.0609 0.0824
Echinococcus granulosus transient receptor potential gamma protein 0.0042 0.0153 0.0208
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Entamoeba histolytica P-glycoprotein 5, putative 0.0036 0.0117 0.0317
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0047 0.0187 0.0253
Echinococcus multilocularis pyruvate kinase 0.0021 0.002 0.0027
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Giardia lamblia Prenyltransferase 0.0064 0.0296 0.0824
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0149 0.0853 0.2342
Echinococcus multilocularis JmjC domain containing protein 4 0.0028 0.0068 0.0092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Trichomonas vaginalis hypothetical protein 0.0049 0.02 0.0495
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0058 0.0257 0.0514
Loa Loa (eye worm) hypothetical protein 0.0036 0.0119 0.0119
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0209 0.1241 0.2481
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0074 0.0364 0.1009
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.0059 0.0127
Schistosoma mansoni vesicular amine transporter 0.0042 0.0153 0.0307
Brugia malayi Pre-SET motif family protein 0.0451 0.2814 0.6046
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0107 0.0144
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.0809 0.4151
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0042 0.0153 0.0208
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0018 0.0003 0.0005
Schistosoma mansoni alpha glucosidase 0.0059 0.0264 0.0528
Schistosoma mansoni phosphatidylserine receptor 0.0028 0.0068 0.0135
Schistosoma mansoni calcium-activated potassium channel 0.0042 0.0153 0.0307
Schistosoma mansoni tyrosine kinase 0.0026 0.0051 0.0101
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0278 0.1688 0.4739
Mycobacterium ulcerans hypothetical protein 0.0171 0.0997 0.5115
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Schistosoma mansoni cytochrome P450 0.0149 0.0853 0.1704
Schistosoma mansoni cellular tumor antigen P53 0.0106 0.0574 0.1148
Echinococcus multilocularis orexin receptor type 2 0.0209 0.1241 0.1681
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0048 0.0197 0.0394
Loa Loa (eye worm) hypothetical protein 0.0044 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.008
Echinococcus multilocularis neuropeptides capa receptor 0.0209 0.1241 0.1681
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0064 0.0296 0.0818
Echinococcus granulosus neuropeptide Y receptor 0.0209 0.1241 0.1681
Schistosoma mansoni neuropeptide receptor 0.0209 0.1241 0.2481
Loa Loa (eye worm) melatonin receptor type 1A 0.0209 0.1241 0.1241
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0153 0.0307
Leishmania major C-8 sterol isomerase-like protein 0.042 0.2615 0.7337
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Plasmodium falciparum lysophospholipase, putative 0.008 0.0404 0.1123
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0884 0.2472
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0566 0.3562 0.712
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Trypanosoma cruzi cytochrome P450, putative 0.0293 0.1789 0.5016
Echinococcus multilocularis adam 0.0129 0.0719 0.0974
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0042 0.0153 0.0307
Schistosoma mansoni growth hormone secretagogue receptor 0.0209 0.1241 0.2481
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0418 0.0835
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0186 0.1091 0.1477
Schistosoma mansoni biogenic amine receptor 0.0209 0.1241 0.2481
Toxoplasma gondii phosphofructokinase PFKII 0.0024 0.0036 0.0095
Schistosoma mansoni growth factor receptor-bound protein 0.0021 0.0019 0.0037
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0117 0.0158
Schistosoma mansoni tyrosine kinase 0.0186 0.1091 0.2181
Echinococcus multilocularis potassium voltage gated channel protein 0.0042 0.0153 0.0208
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0884 0.2472
Echinococcus granulosus intermediate filament protein 0.0031 0.0082 0.0112
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.0187
Leishmania major cyclic nucleotide-binding protein-like protein 0.0074 0.0364 0.1009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0209 0.1241 0.1681
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0119 0.0161
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0117 0.0158
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Onchocerca volvulus 0.0209 0.1241 0.3485
Echinococcus granulosus neuropeptide receptor A26 0.0209 0.1241 0.1681
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Onchocerca volvulus 0.0036 0.0117 0.0329
Loa Loa (eye worm) TK/INSR protein kinase 0.0112 0.0609 0.0609
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0117 0.0158
Onchocerca volvulus 0.0018 0.0003 0.0007
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.0187 0.0253
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.0059 0.008
Echinococcus granulosus ryanodine receptor 44f 0.0042 0.0153 0.0208
Loa Loa (eye worm) hypothetical protein 0.0144 0.0819 0.0819
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Loa Loa (eye worm) AGC/PKG protein kinase 0.0075 0.0369 0.0369
Echinococcus multilocularis 0.0105 0.0567 0.0768
Trypanosoma cruzi pyruvate kinase 2, putative 0.0027 0.0057 0.0147
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.1287
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.0187 0.0253
Onchocerca volvulus 0.0209 0.1241 0.3485
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0062 0.0287 0.0793
Loa Loa (eye worm) GABA receptor subunit 0.0062 0.0285 0.0285
Echinococcus granulosus peptide allatostatin:somatostatin 0.0209 0.1241 0.1681
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0118 0.0651 0.1817
Schistosoma mansoni nuclear receptor 0.0027 0.0059 0.0118
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0074 0.0364 0.0961
Trichomonas vaginalis phosphofructokinase, putative 0.0088 0.0452 0.1207
Echinococcus granulosus short transient receptor potential channel 6 0.0042 0.0153 0.0208
Schistosoma mansoni tyrosine kinase 0.0112 0.0609 0.1217
Echinococcus multilocularis two pore calcium channel protein 2 0.0042 0.0153 0.0208
Loa Loa (eye worm) hypothetical protein 0.0038 0.0131 0.0131
Echinococcus granulosus JmjC domain containing protein 4 0.0028 0.0068 0.0092
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.0059 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0031 0.0081 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0031 0.0081 0.0285
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0874 0.1747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Echinococcus multilocularis shaker cognate 0.0042 0.0153 0.0208
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0022 0.0026 0.0135
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0546 0.3436 0.7381
Echinococcus multilocularis serotonin transporter 0.0276 0.1677 0.227
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Leishmania major mitochondrial DNA topoisomerase II 0.0121 0.0672 0.1875
Leishmania major cytochrome p450-like protein 0.0293 0.1789 0.5016
Loa Loa (eye worm) PHD-finger family protein 0.0088 0.0456 0.0456
Echinococcus multilocularis neuropeptide receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0058 0.0257 0.0257
Echinococcus multilocularis neural cadherin 0.0018 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase type, putative 0.0049 0.02 0.0495
Entamoeba histolytica phosphofructokinase, putative 0.0088 0.0452 0.1258
Echinococcus granulosus a disintegrin and metalloproteinase with 0.035 0.2156 0.2919
Schistosoma mansoni hypothetical protein 0.01 0.0531 0.1061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0257 0.0348
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0062 0.0287 0.0793
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0042 0.0153 0.0424
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0116 0.0157
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0074 0.0362 0.0491
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0152 0.0874 0.1183
Echinococcus multilocularis calcium activated potassium channel 0.0043 0.0159 0.0215
Echinococcus granulosus tyrosine protein kinase HCK 0.0038 0.0131 0.0177
Onchocerca volvulus 0.0153 0.0878 0.2464
Brugia malayi Protein kinase domain containing protein 0.0112 0.0609 0.1308
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus granulosus delta-like protein 1 0.0018 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0209 0.1241 0.2481
Schistosoma mansoni myosin xvIII 0.0209 0.1241 0.2481
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Brugia malayi GnHR receptor homolog 0.0209 0.1241 0.2667
Echinococcus multilocularis serotonin receptor 0.0348 0.2145 0.2904
Brugia malayi Glycosyl hydrolases family 31 protein 0.0059 0.0264 0.0568
Trypanosoma brucei cAMP response protein 1, putative 0.0074 0.0364 0.0959
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0251 0.1516 0.4257
Trypanosoma brucei glucosidase, putative 0.0059 0.0264 0.0677
Schistosoma mansoni slit 0.0018 0.0003 0.0005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0149 0.0853 0.2341
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0187 0.0374
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.1471 0.1471
Echinococcus multilocularis neutral alpha glucosidase AB 0.0059 0.0264 0.0358
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0447 0.5019
Echinococcus multilocularis transient receptor potential cation channel 0.0042 0.0153 0.0208
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0116 0.0635 0.1269
Schistosoma mansoni hypothetical protein 0.0209 0.1241 0.2481
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0024 0.0036 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0117 0.0158
Echinococcus multilocularis neuropeptides capa receptor 0.0209 0.1241 0.1681
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0024 0.0036 0.0088
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Loa Loa (eye worm) TK/EGFR protein kinase 0.0343 0.2115 0.2115
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.1471 0.1471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Trypanosoma brucei pyruvate kinase 1, putative 0.0027 0.0057 0.0092
Brugia malayi hypothetical protein 0.0077 0.038 0.0817
Onchocerca volvulus 0.0065 0.0307 0.0862
Brugia malayi nuclear receptor NHR-88 0.0027 0.0059 0.0127
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.018 0.0493
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Echinococcus granulosus two pore calcium channel protein 1 0.0042 0.0153 0.0208
Echinococcus granulosus tyrosine protein kinase Src42A 0.0059 0.0267 0.0361
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0149 0.0853 0.4373
Entamoeba histolytica P-glycoprotein-5 0.0036 0.0117 0.0317
Trypanosoma cruzi monoglyceride lipase, putative 0.008 0.0404 0.1123
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.08 0.5082 0.688
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0064 0.0296 0.0766
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.2269
Echinococcus multilocularis hyperpolarization activated cyclic 0.0116 0.0635 0.086
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0028 0.0068 0.0177
Mycobacterium ulcerans pyruvate carboxylase 0.0062 0.0287 0.1472
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0107 0.0293
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0042 0.0153 0.033
Echinococcus multilocularis pyruvate kinase 0.0027 0.0057 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.0024 0.0036 0.0033
Echinococcus multilocularis tyrosine protein kinase Blk 0.0049 0.02 0.027
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0152 0.0874 0.0874
Schistosoma mansoni bromodomain containing protein 0.0065 0.0305 0.061
Plasmodium falciparum pyruvate kinase 0.0027 0.0057 0.0147
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0031 0.0081 0.0162
Brugia malayi steroid hormone receptor 0.0058 0.0257 0.0552
Entamoeba histolytica serine/threonine protein kinase, putative 0.0152 0.0874 0.2445
Echinococcus granulosus jumonji domain containing protein 0.0123 0.0681 0.0922
Echinococcus multilocularis lysosomal alpha glucosidase 0.0265 0.1603 0.2171
Brugia malayi voltage-dependent calcium channel 0.0042 0.0153 0.033
Leishmania major hypothetical protein, conserved 0.0074 0.0364 0.1009
Brugia malayi jmjC domain containing protein 0.0028 0.0068 0.0145
Mycobacterium tuberculosis Possible lysophospholipase 0.008 0.0404 0.1075
Schistosoma mansoni nuclear hormone receptor 0.0058 0.0257 0.0514
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0542 0.3405 0.3405
Toxoplasma gondii pyruvate kinase PyK1 0.0027 0.0057 0.0153
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0364 0.0961
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0369 0.0738
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0209 0.1241 0.2481
Echinococcus granulosus voltage gated potassium channel 0.0042 0.0153 0.0208
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0042 0.0153 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0058 0.0257 0.0257
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0209 0.1241 0.1681
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0287 0.0388
Loa Loa (eye worm) hypothetical protein 0.0468 0.2923 0.2923
Leishmania major hypothetical protein, conserved 0.0074 0.0364 0.1009
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0107 0.0234
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0122
Brugia malayi hypothetical protein 0.003 0.008 0.0172
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Echinococcus granulosus cGMP dependent protein kinase 1 0.0075 0.0369 0.05
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0049 0.02 0.0495
Echinococcus granulosus single minded 2 0.0049 0.02 0.027
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0069 0.0329 0.0925
Brugia malayi beta-lactamase 0.0036 0.0119 0.0255
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Brugia malayi Serotonin receptor 0.0209 0.1241 0.2667
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0404 0.1073
Schistosoma mansoni lamin 0.0031 0.0082 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0058 0.0257 0.0552
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.0059 0.0118
Schistosoma mansoni tar DNA-binding protein 0.0155 0.0893 0.1785
Mycobacterium ulcerans hypothetical protein 0.008 0.0404 0.2073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0257 0.0552
Onchocerca volvulus 0.0047 0.0187 0.0525
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Onchocerca volvulus 0.0209 0.1241 0.3485
Schistosoma mansoni tar DNA-binding protein 0.0155 0.0893 0.1785
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.008 0.0109
Echinococcus granulosus lamin dm0 0.0031 0.0082 0.0112
Loa Loa (eye worm) hypothetical protein 0.0088 0.0456 0.0456
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0117 0.0158
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0204 0.1212 0.1641
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0465 0.2904 0.3931
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Brugia malayi Sex muscle abnormal protein 5 0.0021 0.0019 0.004
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0074 0.0364 0.0364
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0157 0.0212
Brugia malayi Cytochrome P450 family protein 0.0186 0.1094 0.235
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0116 0.0635 0.086
Loa Loa (eye worm) beta-lactamase 0.0036 0.0119 0.0119
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0062 0.0284 0.061
Echinococcus granulosus notch 0.0018 0.0003 0.0003
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) cytochrome P450 family protein 0.0293 0.1789 0.1789
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0074 0.0364 0.0727
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0058 0.0257 0.0257
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.007 0.0336 0.0882
Schistosoma mansoni notch 0.0018 0.0003 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.018 0.0493
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Trypanosoma cruzi DNA topoisomerase II, putative 0.0058 0.0258 0.0713
Echinococcus granulosus alpha 1A adrenergic receptor 0.0209 0.1241 0.1681
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0117 0.0261
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0074 0.0364 0.0727
Trichomonas vaginalis adenylate cyclase type III, putative 0.0049 0.02 0.0495
Echinococcus granulosus growth factor receptor bound protein 2 0.0021 0.0019 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.013 0.0352
Echinococcus multilocularis potassium voltage gated channel protein 0.0042 0.0153 0.0208
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0267 0.0361
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0164 0.0952 0.1289
Chlamydia trachomatis DNA gyrase subunit A 0.0318 0.1949 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0247 0.149 0.149
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0566 0.3562 1
Onchocerca volvulus 0.0036 0.0119 0.0334
Echinococcus granulosus tachykinin peptides receptor 99D 0.0209 0.1241 0.1681
Giardia lamblia Pyruvate kinase 0.0027 0.0057 0.0153
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0623 0.1691
Echinococcus multilocularis fibropellin Ia 0.0018 0.0003 0.0003
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.038 0.076
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0149 0.0853 0.2342
Trypanosoma cruzi polo-like protein kinase, putative 0.0152 0.0874 0.2443
Loa Loa (eye worm) steroid hormone receptor 0.0058 0.0257 0.0257
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0042 0.0153 0.0307
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0116 0.0635 0.086
Schistosoma mansoni neuropeptide F-like receptor 0.0209 0.1241 0.2481
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0518
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0369 0.0738
Brugia malayi RNA recognition motif domain containing protein 0.0155 0.0893 0.1918
Trichomonas vaginalis abcb9, putative 0.0036 0.0117 0.0261
Toxoplasma gondii transporter, cation channel family protein 0.0042 0.0153 0.0424
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.018 0.0439
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0209 0.1241 0.2481
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0566 0.3562 1
Echinococcus granulosus shaker cognate 0.0042 0.0153 0.0208
Schistosoma mansoni ap endonuclease 0.0031 0.0081 0.0162
Trypanosoma brucei monoglyceride lipase, putative 0.008 0.0404 0.1073
Echinococcus multilocularis somatostatin receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Echinococcus granulosus histone lysine methyltransferase setb 0.0082 0.0418 0.0565
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0003 0.0005
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0022 0.0026 0.0135
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0042 0.0153 0.0208
Loa Loa (eye worm) hypothetical protein 0.0055 0.0239 0.0239
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0117 0.0158
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0049 0.02 0.0429
Mycobacterium ulcerans 6-phosphofructokinase 0.0088 0.0452 0.2317
Loa Loa (eye worm) hypothetical protein 0.01 0.0531 0.0531
Trypanosoma brucei lanosterol synthase 0.007 0.0336 0.088
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0029 0.007 0.014
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Echinococcus granulosus g-protein coupled receptor 0.0209 0.1241 0.1681
Leishmania major protein kinase A regulatory subunit, putative 0.0074 0.0364 0.1009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Schistosoma mansoni voltage-gated potassium channel 0.059 0.3722 0.7439
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0364 0.0959
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0062 0.0288 0.0576
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0064 0.0296 0.0766
Loa Loa (eye worm) cytochrome P450 family protein 0.0293 0.1789 0.1789
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0623 0.1691
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0024 0.0036 0.0051
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0114 0.0623 0.1743
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0024 0.0036 0.0077
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0059 0.0267 0.0361
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0157 0.0374
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0059 0.0264 0.0677
Brugia malayi Kringle domain containing protein 0.0019 0.0005 0.001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0059 0.0166
Trichomonas vaginalis phosphofructokinase, putative 0.0088 0.0452 0.1207
Onchocerca volvulus 0.0018 0.0003 0.0007
Entamoeba histolytica phosphofructokinase, putative 0.0088 0.0452 0.1258
Schistosoma mansoni hypothetical protein 0.0086 0.0442 0.0884
Echinococcus granulosus peregrin 0.0091 0.0472 0.0639
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0074 0.0364 0.0727
Echinococcus multilocularis neuropeptide receptor 0.0209 0.1241 0.1681
Leishmania major pyruvate kinase 0.0027 0.0057 0.0147
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0042 0.0153 0.033
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.0059 0.0118
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0155 0.0893 0.0893
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0058 0.0263 0.0675
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0107 0.0293
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0149 0.0853 0.2342
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0022 0.0026 0.0067
Loa Loa (eye worm) serotonin transporter b 0.0276 0.1677 0.1677
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0107 0.0232
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0119 0.0321
Brugia malayi Cytochrome P450 family protein 0.0149 0.0853 0.1831
Echinococcus multilocularis allatostatin A receptor 0.0209 0.1241 0.1681
Schistosoma mansoni hypothetical protein 0.01 0.0531 0.1061
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0153 0.0307
Trichomonas vaginalis ap endonuclease, putative 0.0031 0.0081 0.016
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0133 0.0745 0.1009
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0157 0.0337
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0059 0.0264 0.0731
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.008 0.0172
Brugia malayi CXXC zinc finger family protein 0.0033 0.0095 0.0205
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Brugia malayi hypothetical protein 0.0038 0.0132 0.0283
Loa Loa (eye worm) pyruvate kinase 0.0027 0.0057 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.0088 0.0452 0.1207
Entamoeba histolytica hypothetical protein 0.0077 0.038 0.1057
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0042 0.0153 0.033
Brugia malayi nuclear receptor RXR 0.0027 0.0059 0.0127
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0062 0.0284 0.3082
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0024 0.0122
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0031 0.0081 0.0081
Brugia malayi Fibulin-1 precursor 0.0048 0.0197 0.0424
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0042 0.0153 0.0307
Trypanosoma brucei C-8 sterol isomerase, putative 0.042 0.2615 0.7322
Brugia malayi jmjC domain containing protein 0.0028 0.0068 0.0145
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0031 0.0081 0.0416
Loa Loa (eye worm) multidrug resistance protein 3 0.0036 0.0117 0.0117
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0117 0.0158
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0048 0.0197 0.0197
Brugia malayi putative neuropeptide receptor NPR1 0.0209 0.1241 0.2667
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0075 0.0369 0.103
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0062 0.0287 0.1472
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0117 0.0261
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0117 0.0158
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0456 0.1275
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0031 0.0082 0.0218
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0107 0.0232
Brugia malayi AKH receptor 0.0209 0.1241 0.2667
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.0197
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0042 0.0153 0.033
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0069 0.0328 0.0328
Brugia malayi Muscle positioning protein 4 0.0018 0.0003 0.0005
Schistosoma mansoni voltage-gated ion channel 0.0042 0.0153 0.0307
Trypanosoma brucei unspecified product 0.0041 0.0148 0.035
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0062 0.0284 0.0785
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0117 0.0261
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0036 0.0117 0.0264
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0042 0.0153 0.0208
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0041 0.0055
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0042 0.0153 0.033
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0107 0.0287
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0049 0.02 0.0495
Schistosoma mansoni jumonji domain containing protein 0.023 0.1376 0.275
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0059 0.008
Plasmodium vivax amine transporter, putative 0.0047 0.0187 0.0512
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0031 0.0081 0.016
Echinococcus granulosus potassium large conductance calcium activated 0.0042 0.0153 0.0208
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0041 0.0055
Trypanosoma brucei cytochrome P450, putative 0.0293 0.1789 0.4988
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.0809 0.9308
Schistosoma mansoni neuropeptide f receptor 76f 0.0209 0.1241 0.2481
Brugia malayi Bromodomain containing protein 0.0077 0.0381 0.0819
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0318 0.1949 0.547
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0031 0.0081 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0107 0.0144
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0042 0.0153 0.0208
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Brugia malayi ecdysone receptor 0.0027 0.0059 0.0127
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0058 0.0257 0.0514
Echinococcus granulosus microtubule associated protein 2 0.0787 0.5003 0.6773
Schistosoma mansoni laminin gamma-3 chain 0.0018 0.0003 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0676 0.135
Schistosoma mansoni rab6-interacting 0.0038 0.0132 0.0264
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0074 0.0362 0.0724
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0042 0.0153 0.0208
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0102 0.0545 0.1474
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0074 0.0364 0.1009
Brugia malayi cation channel family protein 0.0042 0.0153 0.033
Loa Loa (eye worm) G-protein coupled receptor 0.0209 0.1241 0.1241
Schistosoma mansoni amine GPCR 0.0209 0.1241 0.2481
Toxoplasma gondii kringle domain-containing protein 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0097 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0531 0.0531
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0049 0.02 0.0495
Echinococcus granulosus neuropeptide s receptor 0.0209 0.1241 0.1681
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus multilocularis fmrfamide receptor 0.0209 0.1241 0.1681
Echinococcus granulosus survival motor neuron protein 1 0.0422 0.2627 0.3556
Onchocerca volvulus 0.0209 0.1241 0.3485
Giardia lamblia Rab geranylgeranyltransferase 0.0024 0.0036 0.0094
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0157 0.0427
Echinococcus multilocularis 0.0149 0.0853 0.1154
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0031 0.0082 0.0131
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0042 0.0153 0.0208
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0325 0.1999 0.5606
Loa Loa (eye worm) neuropeptide F receptor 0.0209 0.1241 0.1241
Echinococcus granulosus orexin receptor type 2 0.0209 0.1241 0.1681
Schistosoma mansoni RAR-like nuclear receptor 0.0058 0.0257 0.0514
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0209 0.1241 0.2481
Treponema pallidum exodeoxyribonuclease (exoA) 0.0031 0.0081 0.0127
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0318 0.1949 0.5426
Loa Loa (eye worm) hypothetical protein 0.0029 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0042 0.0157 0.0157
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0676 0.1886
Loa Loa (eye worm) reprolysin 0.0074 0.0362 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0257 0.0552
Mycobacterium tuberculosis Conserved protein 0.0074 0.0364 0.0961
Brugia malayi EGF-like domain containing protein 0.0018 0.0003 0.0005
Mycobacterium ulcerans regulatory protein 0.0074 0.0364 0.1866
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0088 0.0452 0.5071
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Onchocerca volvulus Pyruvate kinase homolog 0.0027 0.0057 0.016
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0079
Brugia malayi Latrophilin receptor protein 2 0.01 0.0531 0.114
Mycobacterium ulcerans hypothetical protein 0.0022 0.0024 0.0122
Treponema pallidum catabolite gene activator (Crp) 0.0074 0.0364 0.0929
Echinococcus granulosus lipoxygenase domain containing protein 0.0038 0.0132 0.0179
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0044
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0074 0.0366 0.0968
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0069 0.0328 0.0444
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0209 0.1241 0.2667
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0676 0.3465
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Echinococcus multilocularis dro:myosuppressin receptor 0.0209 0.1241 0.1681
Mycobacterium ulcerans beta-lactamase 0.0036 0.0119 0.0609
Trichomonas vaginalis ap endonuclease, putative 0.0031 0.0081 0.016
Plasmodium vivax 6-phosphofructokinase, putative 0.0024 0.0036 0.0088
Trichomonas vaginalis adenylate cyclase type III, putative 0.0049 0.02 0.0495
Echinococcus granulosus cGMP dependent protein kinase 0.0075 0.0369 0.05
Leishmania major cytochrome p450-like protein 0.0149 0.0853 0.2383
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0019 0.004
Brugia malayi Melatonin receptor type 1A 0.0209 0.1241 0.2667
Brugia malayi serine/threonine-protein kinase plk-2 0.0152 0.0874 0.1877
Trypanosoma cruzi polo-like protein kinase, putative 0.0152 0.0874 0.2443
Leishmania major trypanothione reductase 0.0038 0.013 0.0352
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0024 0.0036 0.0095
Brugia malayi Thioredoxin reductase 0.0038 0.013 0.0279
Echinococcus granulosus neuropeptide receptor 0.0209 0.1241 0.1681
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0024 0.0122
Onchocerca volvulus 0.0042 0.0153 0.0431
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0049 0.02 0.0495
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0088 0.0452 0.1178
Onchocerca volvulus 0.0209 0.1241 0.3485
Onchocerca volvulus 0.0036 0.0119 0.0334
Leishmania major alpha glucosidase II subunit, putative 0.0059 0.0264 0.073
Brugia malayi 6-phosphofructokinase 0.0088 0.0454 0.0976
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.178 0.4991
Schistosoma mansoni kinase 0.0078 0.0387 0.0774
Echinococcus granulosus neuropeptides capa receptor 0.0209 0.1241 0.1681
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0027 0.0059 0.008
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0149 0.0853 0.2342
Schistosoma mansoni neuropeptide receptor 0.0209 0.1241 0.2481
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Leishmania major protein kinase, putative 0.0075 0.0369 0.1024
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0119 0.0266
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0566 0.3562 1
Leishmania major protein kinase, putative 0.0075 0.0369 0.1024
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0062 0.0287 0.0388
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0089 0.0463 0.2373
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0116 0.0635 0.086
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0022 0.0025 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0209 0.1241 0.2481
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0074 0.0364 0.0493
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Echinococcus granulosus neurogenic locus notch protein 4 0.0018 0.0003 0.0003
Brugia malayi nuclear receptor RXR 0.003 0.008 0.0172
Loa Loa (eye worm) hypothetical protein 0.0681 0.4314 0.4314
Echinococcus multilocularis slit 2 protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0044
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0069 0.0329 0.0925
Brugia malayi larval opioid receptor 0.0209 0.1241 0.2667
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0116 0.0635 0.0635
Brugia malayi neuropeptide F receptor 0.0209 0.1241 0.2667
Echinococcus multilocularis tyrosine protein kinase HCK 0.0038 0.0131 0.0177
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0074 0.0364 0.0781
Schistosoma mansoni pyruvate kinase 0.0027 0.0057 0.0114
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0064 0.0296 0.0766
Onchocerca volvulus 0.0086 0.0442 0.1241
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0042 0.0153 0.0208
Toxoplasma gondii hypothetical protein 0.0024 0.0036 0.0094
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0062 0.0287 0.0388
Echinococcus multilocularis ecdysone induced protein 78C 0.0058 0.0257 0.0348
Brugia malayi ERG2 and Sigma1 receptor like protein 0.042 0.2615 0.5617
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0074 0.0364 0.1009
Echinococcus granulosus lysine specific demethylase 5A 0.0111 0.0602 0.0815
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0119 0.0269
Schistosoma mansoni biogenic amine (5HT) receptor 0.0209 0.1241 0.2481
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0088 0.0452 0.1209
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0116 0.0635 0.1269
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0075 0.0369 0.05
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0163 0.0944 0.2646
Toxoplasma gondii 6-phosphofructokinase 0.0024 0.0036 0.0095
Echinococcus multilocularis glycine receptor subunit beta 0.0069 0.0328 0.0444
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0026 0.0061
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0024 0.0036 0.0088
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0024 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0518
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0074 0.0364 0.0727
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0069 0.0127
Leishmania major hypothetical protein, unknown function 0.0042 0.0153 0.0418
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0046 0.0061
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0042 0.0153 0.033
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0209 0.1241 0.1681
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0157 0.0212
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0074 0.0364 0.0493
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0264 0.0677
Trichomonas vaginalis guanylate cyclase, putative 0.0049 0.02 0.0495
Brugia malayi photoreceptor-specific nuclear receptor 0.0058 0.0257 0.0552
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.0187 0.0253
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0058 0.0257 0.0348
Schistosoma mansoni transient receptor potential channel 4 0.0042 0.0153 0.0307
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0531 0.0719
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0187 0.0402
Echinococcus granulosus sex peptide receptor 0.0209 0.1241 0.1681
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0542 0.3405 0.461
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0209 0.1241 0.1681
Brugia malayi Cytochrome P450 family protein 0.0293 0.1789 0.3843
Plasmodium vivax glutathione reductase, putative 0.0038 0.013 0.0352
Onchocerca volvulus 0.0209 0.1241 0.3485
Loa Loa (eye worm) voltage-dependent calcium channel 0.0042 0.0153 0.0153
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0119 0.0237
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0164 0.0952 0.2045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0168 0.0227
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0086 0.0442 0.095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0068
Trichomonas vaginalis abcb9, putative 0.0036 0.0117 0.0261
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0058 0.0258 0.0661
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0058 0.0257 0.0514
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Brugia malayi Dopamine receptor protein 2 0.0209 0.1241 0.2667
Brugia malayi exodeoxyribonuclease III family protein 0.0031 0.0081 0.0174
Schistosoma mansoni neuropeptide F-like receptor 0.0209 0.1241 0.2481
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0036 0.0117 0.0261
Echinococcus granulosus transient receptor potential cation channel 0.0042 0.0153 0.0208
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0119 0.0161
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0257 0.0552
Brugia malayi nuclear receptor NHR-67 0.0027 0.0059 0.0127
Brugia malayi eukaryotic initiation factor 4A 0.0566 0.3562 0.7652
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0265 0.1603 0.1603
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0456 0.127
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0157 0.0212
Echinococcus granulosus lysosomal alpha glucosidase 0.0265 0.1603 0.2171
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0257 0.0552
Loa Loa (eye worm) G-protein coupled receptor 0.0209 0.1241 0.1241
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0676 0.0915
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0676 0.1891
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0119 0.1127
Leishmania major p-glycoprotein 0.0036 0.0117 0.0316
Leishmania major DNA topoisomerase ii 0.0058 0.0258 0.0713
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0209 0.1241 0.1241
Loa Loa (eye worm) 6-phosphofructokinase 0.0088 0.0452 0.0452
Mycobacterium tuberculosis Conserved hypothetical protein 0.0171 0.0997 0.2751
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Brugia malayi Probable ClpP-like protease 0.0089 0.0463 0.0994
Plasmodium vivax DNA topoisomerase II, putative 0.0069 0.0329 0.0913
Echinococcus multilocularis g-protein coupled receptor 0.0209 0.1241 0.1681
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0114 0.0623 0.3195
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0209 0.1241 0.1681
Echinococcus multilocularis protein jagged 1 0.0018 0.0003 0.0003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0117 0.0158
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0022 0.0026 0.0053
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Schistosoma mansoni steroid hormone receptor ad4bp 0.0058 0.0257 0.0514
Onchocerca volvulus 0.0022 0.0024 0.0067
Echinococcus multilocularis epidermal growth factor receptor 0.0343 0.2115 0.2864
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0042 0.0153 0.0431
Brugia malayi SRC-1 0.0059 0.0267 0.0573
Trichomonas vaginalis phosphofructokinase, putative 0.0024 0.0036 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0149 0.0853 0.2342
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.0602 0.1203
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0024 0.0036 0.0032
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0116 0.0635 0.1269
Toxoplasma gondii thioredoxin reductase 0.0038 0.013 0.0358
Loa Loa (eye worm) hypothetical protein 0.0058 0.0257 0.0257
Chlamydia trachomatis pyruvate kinase 0.0027 0.0057 0.016
Trichomonas vaginalis adenylate cyclase, putative 0.0049 0.02 0.0495
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0069 0.0328 0.0656
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0209 0.1241 0.2667
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0209 0.1241 0.1681
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0149 0.0853 0.4373
Echinococcus granulosus zinc finger protein 0.0021 0.0022 0.0029
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0074 0.0364 0.1015
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0042 0.0153 0.0307
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0028 0.0063 0.0171
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0074 0.0364 0.0959
Echinococcus granulosus voltage gated hydrogen channel 1 0.0042 0.0153 0.0208
Leishmania major pyruvate kinase 0.0027 0.0057 0.0147
Brugia malayi Steroid receptor seven-up type 2 0.0058 0.0257 0.0552
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0119 0.0266
Loa Loa (eye worm) voltage-gated potassium channel 0.0042 0.0153 0.0153
Brugia malayi ADAM-TS Spacer 1 family protein 0.0055 0.0239 0.0514
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0116 0.0635 0.086
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0149 0.0853 0.2342
Schistosoma mansoni tyrosine kinase 0.0059 0.0267 0.0534
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0112 0.0612 0.1223
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0074 0.0364 0.1009
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0059 0.0267 0.0361
Treponema pallidum cyclic nucleotide binding protein 0.0074 0.0364 0.0929
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.0059 0.0118
Schistosoma mansoni notch 0.0018 0.0003 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0257 0.0348
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0153 0.0307
Schistosoma mansoni hypothetical protein 0.0209 0.1241 0.2481
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.008 0.008
Brugia malayi beta-lactamase family protein 0.0036 0.0119 0.0255
Brugia malayi G-protein coupled receptor 0.0209 0.1241 0.2667
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0042 0.0153 0.033
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0031 0.0081 0.0215
Echinococcus multilocularis cpg binding protein 0.0037 0.012 0.0162
Loa Loa (eye worm) ryanodine receptor 0.0042 0.0153 0.0153
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0075 0.0369 0.05
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0117 0.0261
Entamoeba histolytica phosphofructokinase, putative 0.0088 0.0452 0.1258
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0082 0.0418 0.0565
Onchocerca volvulus 0.0209 0.1241 0.3485
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0153 0.0877 0.241
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0059 0.0267 0.0361
Mycobacterium leprae Conserved hypothetical protein 0.0074 0.0364 0.4029
Echinococcus granulosus patatin phospholipase domain containing protein 0.0074 0.0364 0.0493
Loa Loa (eye worm) hypothetical protein 0.0042 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.022 0.1313 0.1313
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0187 0.0374
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0121 0.0672 0.1875
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0031 0.0082 0.0693
Brugia malayi follicle stimulating hormone receptor 0.0675 0.427 0.9173
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0209 0.1241 0.3485
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0042 0.0153 0.0208
Schistosoma mansoni protein phosphatase 2C 0.0028 0.0068 0.0135
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Echinococcus multilocularis peregrin 0.0091 0.0472 0.0639
Trichomonas vaginalis esterase, putative 0.0036 0.0119 0.0266
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.0602 0.1203
Loa Loa (eye worm) hypothetical protein 0.0348 0.2145 0.2145
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0036 0.0117 0.0117
Echinococcus granulosus transient receptor potential cation channel 0.0042 0.0153 0.0208
Loa Loa (eye worm) TYRA-2 protein 0.0209 0.1241 0.1241
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0064 0.0296 0.0635
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0042 0.0153 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0209 0.1241 0.1681
Onchocerca volvulus 0.0027 0.0059 0.0166
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0036 0.0088
Echinococcus granulosus tyrosine protein kinase Src64B 0.0059 0.0267 0.0361
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0022 0.0026 0.0135
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0061 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0147
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Brugia malayi ORL1-like opioid receptor 0.0209 0.1241 0.2667
Loa Loa (eye worm) cytochrome P450 family protein 0.0186 0.1094 0.1094
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0049 0.02 0.0495
Leishmania major carboxylase, putative 0.0062 0.0287 0.0793
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0107 0.0144
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.051 0.1375
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0027 0.0059 0.0118
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.051 0.1375
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0114 0.0623 0.3102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.178 0.4962
Schistosoma mansoni notch 0.0018 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0257 0.0552
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0004
Brugia malayi Pre-SET motif family protein 0.0065 0.0307 0.0659
Brugia malayi Protein kinase domain containing protein 0.0024 0.0037 0.0079
Echinococcus granulosus 7TM GPCR rhodopsin 0.0209 0.1241 0.1681
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0447 0.1197
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0623 0.1738
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0024 0.0036 0.0051
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0152 0.0868 1
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0149 0.0853 0.4373
Trichomonas vaginalis phosphofructokinase, putative 0.0024 0.0036 0.0033
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0042 0.0153 0.0208
Echinococcus granulosus biogenic amine 5HT receptor 0.0348 0.2145 0.2904
Brugia malayi hypothetical protein 0.0209 0.1241 0.2667
Brugia malayi ADAMTS-like protease 0.0055 0.0239 0.0514
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0089 0.0463 0.0626
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0003 0.0003
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0074 0.0364 0.1755
Loa Loa (eye worm) hypothetical protein 0.0209 0.1241 0.1241
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.02 0.0495
Brugia malayi Carboxyl transferase domain containing protein 0.0158 0.0907 0.1949
Schistosoma mansoni voltage-dependent calcium channel 0.0042 0.0153 0.0307
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.005 0.0205 0.051
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0192 0.0384
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0031 0.0081 0.0215
Schistosoma mansoni sodium/chloride dependent transporter 0.0276 0.1677 0.3351
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0055 0.0239 0.0239

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Ability to inhibit DNA supercoiling activity of Escherichia coli gyrase ChEMBL. 17064062
Activity (binding) Displacement of [14C]ciprofloxacin from Escherichia coli gyrase ChEMBL. 17064062
Activity (functional) 0 Ability to inhibit DNA supercoiling activity of Escherichia coli gyrase ChEMBL. 17064062
Activity (binding) 0 Displacement of [14C]ciprofloxacin from Escherichia coli gyrase ChEMBL. 17064062
Activity (functional) 0 Inhibition of Escherichia coli DNA synthesis ChEMBL. 17064062
Activity (functional) 0 Bactericidal activity against Streptococcus pneumoniae SV1 at 0.008 ug/ml by time-kill study ChEMBL. 17261623
Activity (functional) 0 Bactericidal activity against Streptococcus pyogenes C203 at 0.008 ug/ml by time-kill study ChEMBL. 17261623
Activity (functional) 0 Bactericidal activity against Streptococcus pneumoniae SV1 at 2 ug/ml by time-kill study ChEMBL. 17261623
Activity (functional) 0 Bactericidal activity against Streptococcus pyogenes C203 at 2 ug/ml by time-kill study ChEMBL. 17261623
IC50 (functional) = 0.2 uM Inhibition of Escherichia coli gyrase ChEMBL. 17064062
IC50 (binding) = 0.2 uM Inhibition of Escherichia coli H560 DNA gyrase assessed as DNA cleavage ChEMBL. 17196390
IC50 (functional) = 0.2 uM Inhibition of Escherichia coli gyrase ChEMBL. 17064062
MIC (functional) = 0.008 ug ml-1 Antibacterial activity against Streptococcus pneumoniae SVI infected once daily orally dosed CD1 mouse ChEMBL. 17261623
MIC (functional) = 0.015 ug ml-1 Antibacterial activity against Streptococcus pneumonia SVI SP3 ChEMBL. 17064062
MIC (functional) = 0.015 ug ml-1 Antibacterial activity against Streptococcus pyogenes C203 SP1-1 ChEMBL. 17064062
MIC (functional) = 0.015 ug ml-1 Antibacterial activity against Streptococcus pyogenes infected in po dosed mouse ChEMBL. 17064062
MIC (functional) = 0.015 ug ml-1 Antibacterial efficacy against Streptococcus pneumoniae SVI infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 0.015 ug ml-1 Antibacterial efficacy against Streptococcus pyogenes C203 infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 0.015 ug ml-1 Antibacterial activity against Streptococcus pyogenes C-203 SP1-1 ChEMBL. 17196390
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Escherichia coli EC2549 ChEMBL. 17064062
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Peptostreptococcus anaerobius ChEMBL. 17261623
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Peptostreptococcus asaccharolyticus ChEMBL. 17261623
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Peptostreptococcus magnus ChEMBL. 17261623
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Peptostreptococcus prevotii ChEMBL. 17261623
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus pneumoniae 7785 ChEMBL. 17261623
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against quinolone-resistant Streptococcus pneumoniae SP4333 infected twice daily orally dosed CD1 mouse ChEMBL. 17261623
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against membrane efflux-pump deficient Escherichia coli Tol C EC-2549 ChEMBL. 17196390
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against Escherichia coli EC2549 ChEMBL. 17064062
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against membrane efflux-pump deficient Escherichia coli Tol C EC-2549 ChEMBL. 17196390
MIC (functional) = 0.03 ug ml-1 Antibacterial activity against TolC knock-out Escherichia coli by microbroth dilution susceptibility assay ChEMBL. 18752951
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Staphylococcus aureus UC-76 SA-1 ChEMBL. 17064062
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against quinolone-resistant Streptococcus pneumonia SP3763 ChEMBL. 17064062
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Enterococcus faecalis infected in po dosed mouse ChEMBL. 17064062
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Staphylococcus warneri ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against beta-lactamase positive Enterococcus faecalis ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Fusobacterium nucleatum ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Fusobacterium necrophorum ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Fusobacterium sp. ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against oxacillin-susceptible Staphylococcus epidermidis ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Streptococcus pneumoniae 1-970-1 with gyrB Asp435Glu mutation ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial efficacy against methicillin-susceptible Staphylococcus aureus UC76 infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Enterococcus faecalis MGH-2 EF1-1 ChEMBL. 17196390
MIC (functional) = 0.06 ug ml-1 Antibacterial activity against Staphylococcus aureus UC-76 SA-1 ChEMBL. 17196390
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against Haemophilus influenzae HI3542 ChEMBL. 17064062
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against Staphylococcus aureus SA1417 ChEMBL. 17064062
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against methicillin-resistant Staphylococcus aureus SA1417 ChEMBL. 17064062
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against Enterococcus faecalis MGH2 EF1-1 ChEMBL. 17064062
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against vancomycin-intermediate Staphylococcus aureus ChEMBL. 17261623
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against VanA-resistant Enterococcus faecalis ChEMBL. 17261623
MIC (functional) = 0.125 ug ml-1 Antibacterial activity against Streptococcus pneumoniae 1-970-2 with gyrB Asp435Glu, Glu475Ala and parE Pro475Ser mutation ChEMBL. 17261623
MIC (functional) = 0.125 ug ml-1 Antibacterial efficacy against Enterococcus faecalis MGH2 infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 0.13 ug ml-1 Antibacterial activity against Staphylococcus aureus SA2554 ChEMBL. 17064062
MIC (functional) = 0.25 ug ml-1 Antibacterial activity against Moraxella catarrhalis BC3531 ChEMBL. 17064062
MIC (functional) = 0.25 ug ml-1 Antibacterial activity against Staphylococcus aureus SA2552 ChEMBL. 17064062
MIC (functional) = 0.25 ug ml-1 Antibacterial activity against Staphylococcus aureus SA2558 ChEMBL. 17064062
MIC (functional) = 0.25 ug ml-1 Antibacterial activity against Enterococcus faecalis EF1-3524 ChEMBL. 17064062
MIC (functional) = 0.25 ug ml-1 Antibacterial efficacy against methicillin-resistant Staphylococcus aureus SA1417 infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 0.25 ug ml-1 Antibacterial efficacy against ciprofloxacin and methicillin-resistant Staphylococcus aureus SA2017 infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 0.5 ug ml-1 Antibacterial activity against ciprofolxacin-resistant Staphylococcus aureus SA2017 ChEMBL. 17064062
MIC (functional) = 0.5 ug ml-1 Antibacterial activity against VanB-resistant Enterococcus faecium ChEMBL. 17261623
MIC (functional) = 0.5 ug ml-1 Antibacterial activity against Actinomyces sp. ChEMBL. 17261623
MIC (functional) = 0.5 ug ml-1 Antibacterial activity against wild-type Escherichia coli MC4100 by microbroth dilution susceptibility assay ChEMBL. 18752951
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli EC1-10 ChEMBL. 17064062
MIC (functional) = 1 ug ml-1 Antibacterial activity against Klebsiella pneumonia KP2 ChEMBL. 17064062
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli EC2026 ChEMBL. 17064062
MIC (functional) = 1 ug ml-1 Antibacterial activity against vancomycin-resistant Enterococcus faecium EF4-3489 ChEMBL. 17064062
MIC (functional) = 1 ug ml-1 Antibacterial activity against Proteus vulgaris ChEMBL. 17261623
MIC (functional) = 1 ug ml-1 Antibacterial efficacy against Escherichia coli Vogel infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli MC4100 EC-2026 ChEMBL. 17196390
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli EC1-10 ChEMBL. 17064062
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli EC2026 ChEMBL. 17064062
MIC (functional) = 1 ug ml-1 Antibacterial efficacy against Escherichia coli Vogel infected orally dosed CD1 mouse model ChEMBL. 17261623
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli MC4100 EC-2026 ChEMBL. 17196390
MIC (functional) = 2 ug ml-1 Antibacterial activity against Providencia rettgeri PR9 ChEMBL. 17064062
MIC (functional) = 2 ug ml-1 Antibacterial activity against Klebsiella pneumonia ESBL KP3729 ChEMBL. 17064062
MIC (functional) = 4 ug ml-1 Antibacterial activity against Pseudomonas aeruginosa PA7 ChEMBL. 17064062
MIC50 (functional) = 0.004 ug ml-1 Antibacterial activity against Alloiococcus otitidis ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus agalactiae ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus pyogenes ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus bovis ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus sanguis ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against penicillin-intermediate resistant Streptococcus pneumoniae ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against penicillin-resistant Streptococcus pneumoniae ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against levofloxacin-resistant Streptococcus pneumoniae ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus salivarius ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus mitis ChEMBL. 17261623
MIC50 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus viridans ChEMBL. 17261623
MIC50 (functional) = 0.06 ug ml-1 Antibacterial activity against Staphylococcus saprophyticus ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against oxacillin-susceptible Staphylococcus aureus ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against oxacillin-resistant Staphylococcus aureus ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against oxacillin-resistant Staphylococcus epidermidis ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against Staphylococcus haemolyticus ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against Enterococcus faecalis ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against Listeria monocytogenes ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against beta-lactamase negative Haemophilus influenzae ChEMBL. 17261623
MIC50 (functional) = 0.125 ug ml-1 Antibacterial activity against beta-lactamase positive Haemophilus influenzae ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against oxacillin and levofloxacin-resistant Staphylococcus aureus ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against VanB-resistant Enterococcus faecalis ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Enterococcus casseliflavus ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Enterococcus gallinarum ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Corynebacterium jeikeium ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Corynebacterium sp. ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Legionella pneumophila ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against beta-lactamase negative Moraxella catarrhalis ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against beta-lactamase positive Moraxella catarrhalis ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Neisseria gonorrhoeae ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Prevotella bivia ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Prevotella buccae ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Prevotella corporis ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Prevotella melaninogenica ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Prevotella oralis ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Prevotella sp. ChEMBL. 17261623
MIC50 (functional) = 0.25 ug ml-1 Antibacterial activity against Neisseria meningitidis ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Salmonella enterica serovar Paratyphi ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Salmonella enterica serovar Typhimurium ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Salmonella enterica serovar Typhi ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Shigella dysenteriae ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Shigella flexneri ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Shigella sonnei ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Clostridium difficile ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Clostridium perfringens ChEMBL. 17261623
MIC50 (functional) = 0.5 ug ml-1 Antibacterial activity against Salmonella enterica serovar Enteritidis ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Enterococcus faecium ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against VanA-resistant Enterococcus faecium ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Citrobacter diversus ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Enterobacter cloacae ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Klebsiella oxytoca ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Proteus mirabilis ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Acinetobacter sp. ChEMBL. 17261623
MIC50 (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli ChEMBL. 17261623
MIC50 (functional) = 2 ug ml-1 Antibacterial activity against Klebsiella pneumoniae ChEMBL. 17261623
MIC50 (functional) = 2 ug ml-1 Antibacterial activity against beta-lactamase positive Klebsiella pneumoniae ChEMBL. 17261623
MIC50 (functional) = 2 ug ml-1 Antibacterial activity against Morganella morganii ChEMBL. 17261623
MIC50 (functional) = 2 ug ml-1 Antibacterial activity against Serratia marcescens ChEMBL. 17261623
MIC50 (functional) = 2 ug ml-1 Antibacterial activity against Bacteroides fragilis ChEMBL. 17261623
MIC50 (functional) = 2 ug ml-1 Antibacterial activity against Propionibacterium acnes ChEMBL. 17261623
MIC50 (functional) = 4 ug ml-1 Antibacterial activity against Citrobacter freundii ChEMBL. 17261623
MIC50 (functional) = 4 ug ml-1 Antibacterial activity against Enterobacter aerogenes ChEMBL. 17261623
MIC50 (functional) = 4 ug ml-1 Antibacterial activity against Pseudomonas aeruginosa ChEMBL. 17261623
MIC50 (functional) = 4 ug ml-1 Antibacterial activity against Bacteroides ovatus ChEMBL. 17261623
MIC50 (functional) = 4 ug ml-1 Antibacterial activity against Bacteroides thetaiotaomicron ChEMBL. 17261623
MIC50 (functional) = 4 ug ml-1 Antimicrobial activity against Bacteroides distasonis ChEMBL. 17261623
MIC50 (functional) = 8 ug ml-1 Antibacterial activity against Stenotrophomonas maltophilia ChEMBL. 17261623
MIC50 (functional) = 32 ug ml-1 Antibacterial activity against Burkholderia cepacia ChEMBL. 17261623
MIC90 (functional) = 0.008 ug ml-1 Antibacterial activity against Alloiococcus otitidis ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus pyogenes ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus agalactiae ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus bovis ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus sanguis ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against penicillin-resistant Streptococcus pneumoniae ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus salivarius ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus mitis ChEMBL. 17261623
MIC90 (functional) = 0.03 ug ml-1 Antibacterial activity against Streptococcus viridans ChEMBL. 17261623
MIC90 (functional) = 0.06 ug ml-1 Antibacterial activity against penicillin-intermediate resistant Streptococcus pneumoniae ChEMBL. 17261623
MIC90 (functional) = 0.06 ug ml-1 Antibacterial activity against levofloxacin-resistant Streptococcus pneumoniae ChEMBL. 17261623
MIC90 (functional) = 0.125 ug ml-1 Antibacterial activity against oxacillin-susceptible Staphylococcus aureus ChEMBL. 17261623
MIC90 (functional) = 0.125 ug ml-1 Antibacterial activity against oxacillin-resistant Staphylococcus epidermidis ChEMBL. 17261623
MIC90 (functional) = 0.125 ug ml-1 Antibacterial activity against Staphylococcus saprophyticus ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against oxacillin-resistant Staphylococcus aureus ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Enterococcus faecalis ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against VanB-resistant Enterococcus faecalis ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Enterococcus casseliflavus ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Enterococcus gallinarum ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Listeria monocytogenes ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Corynebacterium jeikeium ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Corynebacterium sp. ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against beta-lactamase negative Haemophilus influenzae ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against beta-lactamase positive Haemophilus influenzae ChEMBL. 17261623
MIC90 (functional) = 0.25 ug ml-1 Antibacterial activity against Legionella pneumophila ChEMBL. 17261623
MIC90 (functional) = 0.5 ug ml-1 Antibacterial activity against oxacillin and levofloxacin-resistant Staphylococcus aureus ChEMBL. 17261623
MIC90 (functional) = 0.5 ug ml-1 Antibacterial activity against Staphylococcus haemolyticus ChEMBL. 17261623
MIC90 (functional) = 0.5 ug ml-1 Antibacterial activity against beta-lactamase negative Moraxella catarrhalis ChEMBL. 17261623
MIC90 (functional) = 0.5 ug ml-1 Antibacterial activity against beta-lactamase positive Moraxella catarrhalis ChEMBL. 17261623
MIC90 (functional) = 0.5 ug ml-1 Antibacterial activity against Neisseria gonorrhoeae ChEMBL. 17261623
MIC90 (functional) = 0.5 ug ml-1 Antibacterial activity against Neisseria meningitidis ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Salmonella enterica serovar Paratyphi ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Salmonella enterica serovar Typhimurium ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Salmonella enterica serovar Typhi ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Shigella dysenteriae ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Shigella flexneri ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Shigella sonnei ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Prevotella bivia ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Prevotella buccae ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Prevotella corporis ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Prevotella melaninogenica ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Prevotella oralis ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Prevotella sp. ChEMBL. 17261623
MIC90 (functional) = 1 ug ml-1 Antibacterial activity against Salmonella enterica serovar Enteritidis ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Enterococcus faecium ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against VanA-resistant Enterococcus faecium ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Escherichia coli ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Klebsiella oxytoca ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Proteus mirabilis ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Clostridium difficile ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Clostridium perfringens ChEMBL. 17261623
MIC90 (functional) = 2 ug ml-1 Antibacterial activity against Escherichia coli ChEMBL. 17261623
MIC90 (functional) = 4 ug ml-1 Antibacterial activity against Citrobacter diversus ChEMBL. 17261623
MIC90 (functional) = 4 ug ml-1 Antibacterial activity against Enterobacter cloacae ChEMBL. 17261623
MIC90 (functional) = 4 ug ml-1 Antibacterial activity against Klebsiella pneumoniae ChEMBL. 17261623
MIC90 (functional) = 4 ug ml-1 Antibacterial activity against Bacteroides fragilis ChEMBL. 17261623
MIC90 (functional) = 4 ug ml-1 Antibacterial activity against Propionibacterium acnes ChEMBL. 17261623
MIC90 (functional) = 8 ug ml-1 Antibacterial activity against Enterobacter aerogenes ChEMBL. 17261623
MIC90 (functional) = 8 ug ml-1 Antibacterial activity against beta-lactamase positive Klebsiella pneumoniae ChEMBL. 17261623
MIC90 (functional) = 8 ug ml-1 Antibacterial activity against Morganella morganii ChEMBL. 17261623
MIC90 (functional) = 8 ug ml-1 Antibacterial activity against Acinetobacter sp. ChEMBL. 17261623
MIC90 (functional) = 16 ug ml-1 Antibacterial activity against Citrobacter freundii ChEMBL. 17261623
MIC90 (functional) = 16 ug ml-1 Antibacterial activity against Serratia marcescens ChEMBL. 17261623
MIC90 (functional) = 16 ug ml-1 Antibacterial activity against Bacteroides ovatus ChEMBL. 17261623
MIC90 (functional) = 16 ug ml-1 Antibacterial activity against Bacteroides thetaiotaomicron ChEMBL. 17261623
MIC90 (functional) = 16 ug ml-1 Antimicrobial activity against Bacteroides distasonis ChEMBL. 17261623
MIC90 (functional) = 32 ug ml-1 Antibacterial activity against Pseudomonas aeruginosa ChEMBL. 17261623
MIC90 (functional) = 64 ug ml-1 Antibacterial activity against Burkholderia cepacia ChEMBL. 17261623
MIC90 (functional) = 64 ug ml-1 Antibacterial activity against Stenotrophomonas maltophilia ChEMBL. 17261623
PD50 (functional) = 0.27 mg kg-1 Activity against sc dosed mouse infected with Streptococcus pyogenes ChEMBL. 17064062
PD50 (functional) = 0.7 mg kg-1 Antibacterial efficacy against Streptococcus pyogenes C203 infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 1.4 mg kg-1 Activity against po dosed mouse infected with Streptococcus pyogenes ChEMBL. 17064062
PD50 (functional) = 1.9 mg kg-1 Antibacterial efficacy against methicillin-susceptible Staphylococcus aureus UC76 infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 2.5 mg kg-1 Antibacterial efficacy against methicillin-resistant Staphylococcus aureus SA1417 infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 2.7 mg kg-1 Antibacterial efficacy against Streptococcus pneumoniae SVI infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 3.2 mg kg-1 Antibacterial activity against Streptococcus pneumoniae SVI infected once daily orally dosed CD1 mouse ChEMBL. 17261623
PD50 (functional) = 4.1 mg kg-1 Antibacterial activity against quinolone-resistant Streptococcus pneumoniae SP4333 infected twice daily orally dosed CD1 mouse ChEMBL. 17261623
PD50 (functional) = 4.2 mg kg-1 Activity against sc dosed mouse infected with Enterococcus faecalis ChEMBL. 17064062
PD50 (functional) = 19 mg kg-1 Activity against po dosed mouse infected with Enterococcus faecalis ChEMBL. 17064062
PD50 (functional) = 19 mg kg-1 Antibacterial efficacy against Enterococcus faecalis MGH2 infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 23 mg kg-1 Antibacterial efficacy against ciprofloxacin and methicillin-resistant Staphylococcus aureus SA2017 infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 82 mg kg-1 Antibacterial efficacy against Escherichia coli Vogel infected orally dosed CD1 mouse model ChEMBL. 17261623
PD50 (functional) = 82 mg kg-1 Antibacterial efficacy against Escherichia coli Vogel infected orally dosed CD1 mouse model ChEMBL. 17261623

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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