Detailed information for compound 183921

Basic information

Technical information
  • TDR Targets ID: 183921
  • Name: (1R)-N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxy phenyl)-1H-pyrrol-2-yl]methyl]-1-phenylethana mine
  • MW: 426.572 | Formula: C24H30N2O3S
  • H donors: 1 H acceptors: 2 LogP: 4.08 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN([C@@H](c1ccccc1)C)Cc1ccc([nH]1)c1cc(ccc1OC)S(=O)(=O)CC
  • InChi: 1S/C24H30N2O3S/c1-5-26(18(3)19-10-8-7-9-11-19)17-20-12-14-23(25-20)22-16-21(30(27,28)6-2)13-15-24(22)29-4/h7-16,18,25H,5-6,17H2,1-4H3/t18-/m1/s1
  • InChiKey: WLQQYOGZZSJJST-GOSISDBHSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (1R)-N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxy-phenyl)-1H-pyrrol-2-yl]methyl]-1-phenyl-ethanamine
  • [5-(5-esyl-2-methoxy-phenyl)-1H-pyrrol-2-yl]methyl-ethyl-[(1R)-1-phenylethyl]amine
  • ethyl-[[5-(5-ethylsulfonyl-2-methoxy-phenyl)-1H-pyrrol-2-yl]methyl]-[(1R)-1-phenylethyl]amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dopamine receptor D3 Starlite/ChEMBL No references
Homo sapiens dopamine receptor D2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi hypothetical protein dopamine receptor D3 400 aa 392 aa 19.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi SPARC precursor 0.005 0.0058 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0064 0.0244
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0088 0.0111 0.2115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.0064 0.0064
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.006 0.0095
Mycobacterium ulcerans dehydrogenase/reductase 0.0088 0.0111 0.0172
Brugia malayi ABC transporter transmembrane region family protein 0.0011 0.0004 0.0004
Brugia malayi nuclear receptor NHR-88 0.0054 0.0064 0.0064
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0023 0.002 0.034
Mycobacterium ulcerans short-chain dehydrogenase 0.0088 0.0111 0.0172
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.005 0.0191
Schistosoma mansoni tar DNA-binding protein 0.0233 0.0315 0.0498
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0023 0.0081
Mycobacterium ulcerans ketoacyl reductase 0.0088 0.0111 0.0172
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0088 0.0111 0.2115
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0083 0.0105 0.1999
Loa Loa (eye worm) doublecortin family protein 0.002 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0088 0.0111 0.2115
Mycobacterium ulcerans oxidoreductase 0.0088 0.0111 0.0172
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0376 0.0516 1
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0105 0.1688
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Leishmania major short chain dehydrogenase, putative 0.0088 0.0111 0.2115
Brugia malayi Sulfotransferase domain containing protein 0.0012 0.0004 0.0004
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0041 0.076
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0011 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0321
Onchocerca volvulus 0.0047 0.0054 0.1003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Schistosoma mansoni hypothetical protein 0.0611 0.0847 0.1339
Schistosoma mansoni netrin receptor unc5 0.0015 0.0009 0.0014
Leishmania major hypothetical protein, conserved 0.0376 0.0516 1
Echinococcus multilocularis pikachurin 0.0025 0.0023 0.0081
Echinococcus multilocularis aryl hydrocarbon receptor 0.0023 0.002 0.0071
Echinococcus granulosus hypothetical protein 0.0088 0.0111 0.0431
Echinococcus granulosus microtubule associated protein 2 0.1803 0.2522 1
Schistosoma mansoni multidrug resistance protein 0.0011 0.0004 0.0006
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0153 0.0203 0.0203
Schistosoma mansoni carbonyl reductase 0.0088 0.0111 0.0175
Toxoplasma gondii hypothetical protein 0.0153 0.0203 0.3909
Schistosoma mansoni tar DNA-binding protein 0.0233 0.0315 0.0498
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Giardia lamblia Reductase, putative 0.0088 0.0111 0.2011
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0033 0.0021
Loa Loa (eye worm) hypothetical protein 0.1043 0.1454 0.2301
Schistosoma mansoni survival motor neuron protein 0.0047 0.0054 0.0086
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Schistosoma mansoni nuclear receptor 0.0025 0.0024 0.0037
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0193 0.0259 0.044
Echinococcus multilocularis GPCR, family 2 0.0112 0.0145 0.0565
Plasmodium falciparum transporter, putative 0.0011 0.0003 0.0009
Trypanosoma cruzi multidrug resistance protein E, putative 0.0011 0.0004 0.0032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0028 0.0499
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0011 0.0003 0.0004
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0058 0.1083
Echinococcus multilocularis solute carrier family 5 0.0032 0.0033 0.0124
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0088 0.0111 0.2115
Schistosoma mansoni d-amino acid oxidase 0.4506 0.6322 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Giardia lamblia Short-chain dehydrogenase, putative 0.0088 0.0111 0.2011
Loa Loa (eye worm) RNA binding protein 0.0233 0.0315 0.0498
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0036
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Onchocerca volvulus 0.0025 0.0024 0.0407
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0016 0.0264
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0024 0.0085
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0188 0.0252 0.0991
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0016 0.0264
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0218 0.0294 0.05
Onchocerca volvulus 0.0032 0.0033 0.06
Brugia malayi hypothetical protein 0.0025 0.0024 0.0024
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.0064 0.0244
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0111 0.0184
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0188 0.0252 0.0398
Schistosoma mansoni cellular tumor antigen P53 0.0039 0.0043 0.0067
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0011 0.0004 0.0006
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0023 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0064 0.0101
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0376 0.0516 1
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0083
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0088 0.0111 0.0431
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0233 0.0315 0.0498
Leishmania major short chain dehydrogenase/reductase, putative 0.0088 0.0111 0.2115
Brugia malayi intermediate filament protein 0.0028 0.0027 0.0027
Echinococcus granulosus carbonic anhydrase II 0.0297 0.0405 0.1599
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.0064 0.0064
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0026 0.004
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0033 0.005
Echinococcus multilocularis carbonic anhydrase II 0.0297 0.0405 0.1599
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0051 0.006 0.0092
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0068 0.026
Brugia malayi Dehydrogenases, short chain protein 2 0.0088 0.0111 0.0111
Echinococcus multilocularis RUN 0.002 0.0016 0.0056
Brugia malayi secreted modular calcium-binding protein 1 0.005 0.0058 0.0058
Leishmania major hypothetical protein, conserved 0.0376 0.0516 1
Loa Loa (eye worm) hypothetical protein 0.4506 0.6322 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004
Onchocerca volvulus 0.0012 0.0004 0.0034
Onchocerca volvulus 0.0039 0.0043 0.0777
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0088 0.0111 0.2115
Schistosoma mansoni intermediate filament proteins 0.0028 0.0027 0.0042
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0024 0.0037
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0032 0.0033 0.0124
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0016 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0051 0.006 0.023
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0073 0.009 0.0143
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Brugia malayi sodium-independent organic anion transporter family protein 0.0073 0.009 0.009
Echinococcus granulosus WW domain containing oxidoreductase 0.0088 0.0111 0.0431
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0033 0.005
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.0033 0.0049
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0011 0.0004 0.0032
Brugia malayi nuclear receptor NHR-67 0.0025 0.0024 0.0024
Giardia lamblia Kinase, CMGC MAPK 0.0083 0.0105 0.19
Leishmania major p-glycoprotein e 0.0011 0.0004 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Schistosoma mansoni heparan sulfate n-deacetylase/n-sulfotransferase 0.0012 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0053 0.0063 0.0099
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0083 0.0105 0.1999
Schistosoma mansoni organic anion transporter 0.0073 0.009 0.0143
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0088 0.0111 0.2115
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0188 0.0252 0.4862
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0297 0.0405 0.0405
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0376 0.0516 1
Echinococcus granulosus pikachurin 0.0025 0.0023 0.0081
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.0033 0.0049
Loa Loa (eye worm) norepinephrine transporter 0.0062 0.0075 0.0119
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0033 0.0606
Echinococcus multilocularis carbonyl reductase 1 0.0088 0.0111 0.0431
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0088 0.0111 0.0144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Loa Loa (eye worm) solute carrier family 6 member 4 0.0062 0.0075 0.0119
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0088 0.0111 0.2006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.005 0.0079
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0028 0.0102
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.2115
Brugia malayi sodium-independent organic anion transporter family protein 0.0073 0.009 0.009
Echinococcus granulosus RUN 0.002 0.0016 0.0056
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0088 0.0111 0.0184
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase GlpD2 0.0376 0.0516 0.0813
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Schistosoma mansoni zinc finger protein 0.0025 0.0024 0.0037
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0112 0.0145 0.0565
Echinococcus multilocularis slit 2 protein 0.0025 0.0023 0.0081
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.0033 0.0606
Echinococcus multilocularis musashi 0.0028 0.0027 0.0098
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.0064 0.0244
Schistosoma mansoni sodium/chloride dependent transporter 0.0011 0.0004 0.0006
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0297 0.0405 0.0405
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0088 0.0111 0.0184
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.005 0.0079
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.0033 0.0049
Trypanosoma brucei carbonic anhydrase-like protein 0.0297 0.0405 0.7847
Onchocerca volvulus 0.0017 0.0012 0.0173
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0023 0.002 0.0071
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0041 0.076
Echinococcus granulosus multidrug resistance associated protein 7 0.0011 0.0004 0.0007
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0297 0.0405 0.0641
Leishmania major short chain dehydrogenase-like protein 0.0088 0.0111 0.2115
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0011 0.0004 0.0032
Brugia malayi ecdysone receptor 0.0025 0.0024 0.0024
Brugia malayi Sulfotransferase domain containing protein 0.0012 0.0004 0.0004
Echinococcus multilocularis carbonic anhydrase 0.0153 0.0203 0.0797
Brugia malayi hypothetical protein 0.0028 0.0028 0.0028
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0004
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0094 0.0366
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0088 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0024 0.0085
Echinococcus granulosus carbonyl reductase 1 0.0088 0.0111 0.0431
Brugia malayi nuclear receptor NHR-88 0.0025 0.0024 0.0024
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0088 0.0111 0.0184
Leishmania major protein kinase, putative 0.0024 0.0021 0.0369
Schistosoma mansoni hypothetical protein 0.0611 0.0847 0.1339
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Trypanosoma brucei short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Brugia malayi nuclear receptor RXR 0.0025 0.0024 0.0024
Echinococcus multilocularis dna polymerase eta 0.002 0.0016 0.0054
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0028 0.0102
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0064 0.0101
Leishmania major carbonic anhydrase-like protein 0.0297 0.0405 0.7847
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0088 0.0111 0.2115
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0188 0.0252 0.0252
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0111 0.0184
Echinococcus granulosus cpg binding protein 0.0018 0.0013 0.0042
Plasmodium vivax steroid dehydrogenase, putative 0.0088 0.0111 0.2115
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Loa Loa (eye worm) cytochrome P450 0.0032 0.0033 0.0053
Echinococcus multilocularis conserved hypothetical protein 0.0088 0.0111 0.0431
Schistosoma mansoni multidrug resistance protein 0.0011 0.0004 0.0006
Brugia malayi Uncoordinated protein 44 0.0015 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.0064 0.0101
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0376 0.0516 1
Echinococcus granulosus hypothetical protein 0.0718 0.0997 0.3948
Loa Loa (eye worm) dehydrogenase 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0091
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0033 0.0606
Brugia malayi hypothetical protein 0.0088 0.0111 0.0111
Schistosoma mansoni fad oxidoreductase 0.0376 0.0516 0.0816
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0088 0.0111 0.2115
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0395 0.0544 1
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0088 0.0111 0.0184
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0063 0.1177
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.002 0.0083
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0023 0.002 0.0349
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0036
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0014 0.0007 0.0102
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0064 0.0244
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0007 0.0018
Echinococcus granulosus death domain containing protein 0.0015 0.0009 0.0025
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0088 0.0111 0.0184
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Schistosoma mansoni slit 0.0025 0.0023 0.0036
Schistosoma mansoni carbonic anhydrase 0.0153 0.0203 0.0321
Toxoplasma gondii carbonyl reductase 1, putative 0.0088 0.0111 0.2115
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0033 0.005
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0023 0.0081
Onchocerca volvulus Putative fad oxidoreductase 0.0376 0.0516 1
Echinococcus multilocularis 0.0032 0.0033 0.0124
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0033 0.005
Echinococcus granulosus multidrug resistance associated protein 1 0.0011 0.0004 0.0007
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0011 0.0004 0.0032
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0088 0.0111 0.0172
Loa Loa (eye worm) hypothetical protein 0.0027 0.0026 0.0042
Brugia malayi hypothetical protein 0.0028 0.0028 0.0028
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Echinococcus granulosus bifunctional heparan sulfate 0.0012 0.0004 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.0064 0.0101
Leishmania major pentamidine resistance protein 1 0.0011 0.0004 0.0032
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0041 0.076
Giardia lamblia DINP protein human, muc B family 0.002 0.0016 0.0255
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Brugia malayi laminin alpha chain 0.0025 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0112 0.0145 0.0229
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0088 0.0111 0.0184
Mycobacterium ulcerans short-chain dehydrogenase 0.0088 0.0111 0.0172
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0088 0.0111 0.2115
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.0064 0.0064
Onchocerca volvulus 0.0073 0.009 0.1709
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.4506 0.6322 1
Leishmania major cytochrome p450-like protein 0.0032 0.0033 0.0606
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0088 0.0111 0.0431
Onchocerca volvulus 0.005 0.0058 0.1075
Giardia lamblia Multidrug resistance-associated protein 1 0.0011 0.0004 0.0036
Echinococcus multilocularis multidrug resistance associated protein 1 0.0011 0.0004 0.0007
Echinococcus multilocularis conserved hypothetical protein 0.071 0.0986 0.3902
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.0313 0.1233
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Echinococcus granulosus carbonic anhydrase 0.0153 0.0203 0.0797
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0044
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0011 0.0003 0.0002
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0023 0.0397
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0144
Mycobacterium ulcerans carveol-like dehydrogenase 0.0088 0.0111 0.0172
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.0064 0.0244
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.0033 0.0049
Trypanosoma brucei unspecified product 0.002 0.0016 0.0264
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0011 0.0003 0.0004
Mycobacterium ulcerans glycolipid sulfotransferase 0.0012 0.0004 0.0004
Echinococcus granulosus carbonyl reductase 1 0.0088 0.0111 0.0431
Brugia malayi Calcitonin receptor-like protein seb-1 0.0353 0.0484 0.0484
Schistosoma mansoni hypothetical protein 0.0112 0.0145 0.0229
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0032 0.0033 0.0124
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0376 0.0516 0.9486
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0088 0.0111 0.2115
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0004 0.0031
Brugia malayi hypothetical protein 0.0073 0.009 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Onchocerca volvulus Putative organic anion transporter 0.0073 0.009 0.1709
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0376 0.0516 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0091
Mycobacterium tuberculosis Probable sulfatase 0.0218 0.0294 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Entamoeba histolytica hypothetical protein, conserved 0.0088 0.0111 0.2006
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0063 0.0096
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0009 0.0025
Onchocerca volvulus 0.0088 0.0111 0.2108
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.005 0.0191
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.0064 0.0101
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0016 0.0016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.005 0.0191
Brugia malayi oxidoreductase 0.0088 0.0111 0.0111
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0395 0.0544 1
Brugia malayi Death domain containing protein 0.0015 0.0009 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Loa Loa (eye worm) RecQ helicase 0.0041 0.0046 0.0073
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0184
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Echinococcus multilocularis agrin 0.005 0.0058 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0144
Brugia malayi conserved hypotetical protein 0.0025 0.0024 0.0024
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0088 0.0111 0.0184
Echinococcus multilocularis sodium and chloride dependent glycine 0.0011 0.0003 0.0002
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.0033 0.0049
Echinococcus granulosus carbonyl reductase 1 0.0088 0.0111 0.0431
Schistosoma mansoni NAD dehydrogenase 0.0376 0.0516 0.0816
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.0064 0.0064
Loa Loa (eye worm) transcription factor SMAD2 0.0101 0.013 0.0206
Schistosoma mansoni cpg binding protein 0.0018 0.0013 0.002
Leishmania major DNA polymerase eta, putative 0.002 0.0016 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Schistosoma mansoni hypothetical protein 0.0047 0.0054 0.0086
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0011 0.0003 0.0002
Schistosoma mansoni lipoxygenase 0.002 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0027
Schistosoma mansoni agrin 0.005 0.0058 0.0091
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.0064 0.0244
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0218 0.0294 0.0465
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0188 0.0252 0.0395
Onchocerca volvulus 0.0028 0.0027 0.0471
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Schistosoma mansoni retinal dehydrogenase 0.0088 0.0111 0.0175
Schistosoma mansoni rab6-interacting 0.002 0.0016 0.0026
Schistosoma mansoni inositol transporter 0.0032 0.0033 0.0053
Schistosoma mansoni carbonic anhydrase-related 0.0153 0.0203 0.0321
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0376 0.0516 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0032 0.0572
Echinococcus multilocularis retinol dehydrogenase 13 0.0088 0.0111 0.0431
Brugia malayi hypothetical protein 0.0025 0.0024 0.0024
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0041 0.0483
Trypanosoma brucei unspecified product 0.0014 0.0007 0.0095
Mycobacterium tuberculosis Possible oxidoreductase 0.0088 0.0111 0.0184
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0009
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0088 0.0111 0.2115
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0027 0.0027
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.0064 0.1187
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0046 0.0572
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0022 0.0382
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Loa Loa (eye worm) hypothetical protein 0.0059 0.0071 0.0112
Echinococcus multilocularis transient receptor potential cation channel 0.0088 0.0111 0.0431
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0095
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Giardia lamblia Multidrug resistance-associated protein 1 0.0011 0.0004 0.0031
Brugia malayi nuclear hormone receptor 0.0025 0.0024 0.0024
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0218 0.0294 0.05
Loa Loa (eye worm) CXXC zinc finger family protein 0.0017 0.0012 0.0018
Brugia malayi Sulfatase family protein 0.0218 0.0294 0.0294
Toxoplasma gondii hypothetical protein 0.0011 0.0003 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0024 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0376 0.0516 0.0816
Trypanosoma brucei p-glycoprotein 0.0011 0.0004 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Loa Loa (eye worm) hypothetical protein 0.0218 0.0294 0.0465
Brugia malayi Cytochrome P450 family protein 0.0053 0.0063 0.0063
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0193 0.0259 0.038
Brugia malayi prostaglandin transporter 0.0073 0.009 0.009
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0011 0.0003 0.0002
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0025 0.0023 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0032
Schistosoma mansoni sodium/solute symporter 0.0032 0.0033 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0033 0.005
Echinococcus granulosus intermediate filament protein 0.0028 0.0027 0.0098
Brugia malayi Inositol-1 0.0038 0.0041 0.0041
Onchocerca volvulus 0.0012 0.0004 0.0034
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0062 0.0075 0.0075
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0051 0.006 0.023
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0088 0.0111 0.1801
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0376 0.0516 1
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0218 0.0294 0.5268
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0011 0.0004 0.0032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0008 0.0117
Schistosoma mansoni hypothetical protein 0.003 0.0031 0.0048
Toxoplasma gondii oxidoreductase, putative 0.0088 0.0111 0.2115
Mycobacterium tuberculosis Probable dehydrogenase 0.0088 0.0111 0.0184
Echinococcus multilocularis lamin dm0 0.0028 0.0027 0.0098
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0021 0.0369
Echinococcus multilocularis high affinity choline transporter 1 0.0294 0.0402 0.1585
Schistosoma mansoni carbonic anhydrase-related 0.0153 0.0203 0.0321
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0088 0.0111 0.2006
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.01 0.0129 0.0204
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0802 0.1116 0.4418
Giardia lamblia Fructose-bisphosphate aldolase 0.0395 0.0544 1
Loa Loa (eye worm) hypothetical protein 0.0241 0.0327 0.0517
Mycobacterium tuberculosis Possible hydrolase 0.0218 0.0294 0.05
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0153 0.0203 0.0203
Chlamydia trachomatis D-amino acid dehydrogenase 0.0376 0.0516 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0041 0.0155
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0088 0.0111 0.2006
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Mycobacterium ulcerans ketoacyl reductase 0.0088 0.0111 0.0172
Onchocerca volvulus 0.0088 0.0111 0.2108
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0088 0.0111 0.0184
Schistosoma mansoni carbonyl reductase 0.0088 0.0111 0.0175
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0028 0.0044
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0073 0.009 0.035
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0016 0.0264
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0033 0.0124
Echinococcus granulosus aryl hydrocarbon receptor 0.0023 0.002 0.0071
Onchocerca volvulus 0.0028 0.0027 0.0471
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0088 0.0111 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0004 0.0031
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0024 0.0037
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0058 0.0069 0.0264
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004
Brugia malayi tailless protein 0.0025 0.0024 0.0024
Echinococcus multilocularis dnaJ subfamily B 0.024 0.0325 0.1283
Brugia malayi nuclear hormone receptor 0.0054 0.0064 0.0064
Brugia malayi Retinol dehydrogenase 12 0.0088 0.0111 0.0111
Trypanosoma brucei short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Echinococcus multilocularis mitogen activated protein kinase 0.0083 0.0105 0.0407
Echinococcus granulosus sodium and chloride dependent glycine 0.0011 0.0003 0.0002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0112 0.0145 0.0145
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0064 0.0101
Echinococcus granulosus sodium and chloride dependent glycine 0.0011 0.0003 0.0002
Echinococcus granulosus dna polymerase kappa 0.002 0.0016 0.0054
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Brugia malayi Cytochrome P450 family protein 0.0032 0.0033 0.0033
Echinococcus multilocularis geminin 0.0611 0.0847 0.3351
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0024 0.0037
Brugia malayi GH02984p 0.0294 0.0402 0.0402
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0031
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0376 0.0516 1
Brugia malayi hypothetical protein 0.0088 0.0111 0.0111
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0008 0.0117
Brugia malayi hypothetical protein 0.002 0.0016 0.0016
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0376 0.0516 0.2038
Giardia lamblia Multidrug resistance-associated protein 1 0.0011 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0062 0.0075 0.0119
Toxoplasma gondii oxidoreductase, putative 0.0088 0.0111 0.2115
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.0064 0.0101
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0064 0.0064
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0088 0.0111 0.0175
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0088 0.0111 0.2115
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0009 0.0014
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.003 0.0031 0.0113
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.0033 0.0049
Loa Loa (eye worm) inositol-1 0.0038 0.0041 0.0065
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0004 0.0032
Leishmania major cytochrome p450-like protein 0.0032 0.0033 0.0606
Onchocerca volvulus 0.0088 0.0111 0.2108
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0111 0.0184
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0016 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.005 0.0079
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0011 0.0004 0.0032
Echinococcus granulosus steroid dehydrogenase 0.0088 0.0111 0.0431
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0083 0.0105 0.0166
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.002 0.0083
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0153 0.0203 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Onchocerca volvulus 0.0062 0.0075 0.1414
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0038 0.0041 0.0065
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.002 0.0083
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.0033 0.0049
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.002 0.0083
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0297 0.0405 0.0641
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0095
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0027 0.0042
Giardia lamblia MRP-like ABC transporter 0.0011 0.0004 0.0036
Schistosoma mansoni lipoxygenase 0.0057 0.0068 0.0107
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0376 0.0516 0.2038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0064 0.0064
Schistosoma mansoni aryl hydrocarbon receptor 0.0088 0.0112 0.0177
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0024 0.0085
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0021 0.0369
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0063 0.0099
Brugia malayi dehydrogenases, short chain protein 9 0.0088 0.0111 0.0111
Echinococcus granulosus oxidoreductase 0.0088 0.0111 0.0431
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0088 0.0111 0.1801
Schistosoma mansoni high-affinity choline transporter 0.0294 0.0402 0.0635
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0376 0.0516 1
Brugia malayi dehydrogenases, short chain protein 2 0.0088 0.0111 0.0111
Echinococcus multilocularis microtubule associated protein 2 0.1803 0.2522 1
Trypanosoma brucei protein kinase, putative 0.0083 0.0105 0.1999
Trypanosoma cruzi MFS transporter, putative 0.0073 0.009 0.1717
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0016 0.0054
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0011 0.0003 0.0004
Schistosoma mansoni carbonyl reductase 0.0088 0.0111 0.0175
Schistosoma mansoni microtubule-associated protein tau 0.1803 0.2522 0.399
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.002 0.0083
Schistosoma mansoni loxhd1 0.002 0.0016 0.0026
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0024 0.0024
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0297 0.0405 0.0641
Entamoeba histolytica hypothetical protein 0.003 0.0031 0.0526
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0024 0.0037
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0012 0.0004 0.0007
Mycobacterium ulcerans D-amino acid oxidase Aao 0.4506 0.6322 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0023 0.002 0.0349
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0112 0.0145 0.0565
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0218 0.0294 0.5268
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0041 0.0483
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0088 0.0111 0.0175
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.0033 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0296 0.0404 0.064
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.0033 0.0049
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0088 0.0111 0.2006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.0064 0.0244
Schistosoma mansoni sodium-dependent amino acid transporter 0.0011 0.0003 0.0004
Brugia malayi hypothetical protein 0.0231 0.0313 0.0313
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0376 0.0516 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.0064 0.0244
Loa Loa (eye worm) TAR-binding protein 0.0233 0.0315 0.0498
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0054 0.0063 0.01
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0023 0.002 0.0032
Mycobacterium ulcerans short-chain dehydrogenase 0.0088 0.0111 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Trypanosoma brucei unspecified product 0.0014 0.0007 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0033 0.005
Brugia malayi nuclear receptor RXR 0.0028 0.0028 0.0028
Brugia malayi PAS domain containing protein 0.0088 0.0112 0.0112
Onchocerca volvulus 0.0088 0.0111 0.2108
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0016 0.002
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0088 0.0111 0.0111
Leishmania major hypothetical protein, conserved 0.0088 0.0111 0.2115
Brugia malayi photoreceptor-specific nuclear receptor 0.0054 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.003 0.0031 0.0526
Mycobacterium ulcerans arylsulfatase, AslA 0.0218 0.0294 0.0462
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0028 0.0028
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.0033 0.0049
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.0064 0.1187
Toxoplasma gondii hypothetical protein 0.0376 0.0516 1
Onchocerca volvulus 0.002 0.0016 0.0266
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.0064 0.0064
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0064 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0024 0.0024
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0016 0.0056
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0088 0.0111 0.0172
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0051 0.006 0.1128
Schistosoma mansoni cpg binding protein 0.0017 0.0012 0.0018
Echinococcus multilocularis carbonic anhydrase 0.0153 0.0203 0.0797
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.0033 0.0606
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0036 0.0038 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.0064 0.0101
Schistosoma mansoni carbonic anhydrase-related 0.0153 0.0203 0.0321
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.0033 0.0049
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0024 0.0024
Loa Loa (eye worm) latrophilin receptor protein 2 0.0112 0.0145 0.0229
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0376 0.0516 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0028 0.0044
Mycobacterium leprae Probable oxidoreductase 0.0088 0.0111 0.0144
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0033 0.005
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0088 0.0111 0.2006
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Brugia malayi multidrug resistance related protein 1 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Onchocerca volvulus 0.0088 0.0111 0.2108
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.003 0.0031 0.0113
Brugia malayi cytochrome P450 0.0032 0.0033 0.0033
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0088 0.0111 0.0431
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0105 0.1688
Echinococcus granulosus mitogen activated protein kinase 0.0083 0.0105 0.0407
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0041 0.0721
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0036 0.0054
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0011 0.0004 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0016 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0028 0.0478
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0026
Mycobacterium ulcerans glycolipid sulfotransferase 0.0012 0.0004 0.0004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0033 0.005
Brugia malayi Doublecortin family protein 0.002 0.0016 0.0016
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0016 0.0264
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0016 0.0056
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.0064 0.0101
Echinococcus granulosus mitogen activated protein kinase 3 0.0083 0.0105 0.0407
Echinococcus multilocularis cpg binding protein 0.0018 0.0013 0.0042
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.001 0.0002 0.0003
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0088 0.0111 0.0431
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Schistosoma mansoni cell polarity protein 0.0025 0.0023 0.0036
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0009 0.0116
Onchocerca volvulus 0.0088 0.0111 0.2108
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0036 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0095
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0083 0.0105 0.1999
Brugia malayi hypothetical protein 0.003 0.0031 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0188 0.0252 0.0427
Leishmania major short chain dehydrogenase/reductase, putative 0.0088 0.0111 0.2115
Entamoeba histolytica hypothetical protein 0.003 0.0031 0.0526
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Echinococcus multilocularis bifunctional heparan sulfate 0.0012 0.0004 0.0009
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0058 0.0058
Loa Loa (eye worm) serotonin transporter b 0.0062 0.0075 0.0119
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.005 0.0079
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0088 0.0111 0.0184
Brugia malayi hypothetical protein 0.0011 0.0003 0.0003
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0041 0.076
Echinococcus multilocularis follistatin 0.005 0.0058 0.0221
Schistosoma mansoni sodium/chloride dependent transporter 0.0062 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Mycobacterium ulcerans dehydrogenase 0.0088 0.0111 0.0172
Echinococcus granulosus sodium:glucose cotransporter 2 0.0032 0.0033 0.0124
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0024 0.0085
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0033 0.005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0033 0.005
Echinococcus multilocularis tumor protein p63 0.0266 0.0362 0.1426
Echinococcus granulosus slit 2 protein 0.0025 0.0023 0.0081
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Entamoeba histolytica hypothetical protein 0.0088 0.0111 0.2006
Schistosoma mansoni DNA polymerase eta 0.002 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0006
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0058 0.0058
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0011 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0105 0.1688
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0032 0.0542
Mycobacterium leprae Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase) 0.0376 0.0516 0.0787
Echinococcus multilocularis steroid dehydrogenase 0.0088 0.0111 0.0431
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0076 0.012
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0088 0.0111 0.0431
Mycobacterium ulcerans hydrolase 0.0218 0.0294 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0028 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0024 0.0407
Leishmania major oxidoreductase-like protein 0.0088 0.0111 0.2115
Mycobacterium tuberculosis Possible oxidoreductase 0.0088 0.0111 0.0184
Entamoeba histolytica multidrug resistance protein, putative 0.0011 0.0004 0.0031
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0024 0.0024
Treponema pallidum sodium- and chloride- dependent transporter 0.0062 0.0075 0.1252
Schistosoma mansoni hypothetical protein 0.0112 0.0145 0.0229
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.0376 0.0516 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0088 0.0111 0.0184
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0088 0.0111 0.0431
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0088 0.0111 0.2115
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0088 0.0111 0.2108
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.005 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0033 0.005
Onchocerca volvulus 0.0088 0.0111 0.2108
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0016 0.0054
Echinococcus multilocularis retinol dehydrogenase 11 0.0088 0.0111 0.0431
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0025 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0024 0.0037
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0009 0.0025
Schistosoma mansoni single-minded 0.0088 0.0112 0.0177
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0033 0.005
Leishmania major hypothetical protein, conserved 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Mycobacterium ulcerans aldehyde dehydrogenase 0.0051 0.006 0.0092
Echinococcus granulosus lamin dm0 0.0028 0.0027 0.0098
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0188 0.0252 0.0991
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.0033 0.0606
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0088 0.0111 0.2115
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.0062 0.0075 0.0119
Entamoeba histolytica ABC transporter, putative 0.0011 0.0004 0.0031
Echinococcus multilocularis expressed protein 0.005 0.0058 0.0221
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0016 0.0275
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0058 0.1083
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0023 0.002 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0024 0.0085
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0041 0.076
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0091
Schistosoma mansoni nuclear receptor 0.0025 0.0024 0.0037
Plasmodium falciparum steroid dehydrogenase, putative 0.0088 0.0111 0.2115
Onchocerca volvulus 0.0073 0.009 0.1709
Schistosoma mansoni sodium/chloride dependent transporter 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0033 0.005
Schistosoma mansoni hypothetical protein 0.0015 0.0009 0.0014
Onchocerca volvulus 0.0073 0.009 0.1709
Schistosoma mansoni hypothetical protein 0.0032 0.0033 0.0053
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.413 0.5794 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0088 0.0111 0.1801
Schistosoma mansoni hypothetical protein 0.0241 0.0327 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.0083 0.0105 0.1688
Loa Loa (eye worm) dehydrogenase 0.0088 0.0111 0.0175
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0024 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0064 0.0064
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.0064 0.0101
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Echinococcus granulosus tar DNA binding protein 0.0233 0.0315 0.1241
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0033 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0064 0.0244
Mycobacterium ulcerans ketoacyl reductase 0.0088 0.0111 0.0172
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0083 0.0105 0.1999
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.0064 0.0101
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0009 0.0025
Schistosoma mansoni lamin 0.0028 0.0027 0.0042
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0041 0.0155
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.0064 0.0101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Mycobacterium leprae putative cytochrome p450 0.0032 0.0033 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0004 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0026 0.0041
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0802 0.1116 0.4418
Loa Loa (eye worm) abnormal epIthelia family member 0.0025 0.0023 0.0036
Echinococcus granulosus sodium:myo inositol cotransporter 0.0032 0.0033 0.0124
Brugia malayi Dehydrogenases, short chain protein 30 0.0088 0.0111 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0044
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0111 0.0184
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0016 0.0264
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0016 0.0275
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0058 0.1083
Giardia lamblia Hypothetical protein 0.0088 0.0111 0.2011
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0023 0.002 0.0083
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0376 0.0516 1
Echinococcus granulosus Solute carrier organic anion transporter family 0.0073 0.009 0.035
Schistosoma mansoni organic anion transporter 0.0073 0.009 0.0143
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Brugia malayi Sodium:solute symporter family protein 0.0032 0.0033 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0003 0.0009
Schistosoma mansoni coup transcription factor 0.0054 0.0064 0.0101
Mycobacterium ulcerans aldehyde dehydrogenase 0.0051 0.006 0.0092
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0088 0.0111 0.0172
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.0033 0.0049
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.0033 0.0049
Onchocerca volvulus 0.0025 0.0024 0.0407
Loa Loa (eye worm) hypothetical protein 0.0376 0.0516 0.0816
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0024 0.0037
Brugia malayi Cytochrome P450 family protein 0.0053 0.0063 0.0063
Loa Loa (eye worm) DR-78 0.0025 0.0024 0.0037
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0218 0.0294 0.5675
Leishmania major ABC-thiol transporter 0.0011 0.0004 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0064 0.0244
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0062 0.0075 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Entamoeba histolytica short chain dehydrogenase family protein 0.0088 0.0111 0.2006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Toxoplasma gondii hypothetical protein 0.0011 0.0003 0.0009
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0088 0.0111 0.2115
Leishmania major hypothetical protein, conserved 0.0088 0.0111 0.2115
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.0033 0.0049
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase 0.0376 0.0516 0.0813
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0024 0.0037
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0083 0.0105 0.1999
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0051 0.006 0.0096
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0024 0.0085
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0028 0.0499
Entamoeba histolytica hypothetical protein, conserved 0.0088 0.0111 0.2006
Brugia malayi Protein kinase domain containing protein 0.0016 0.001 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0063 0.1177
Giardia lamblia ABC transporter, putative 0.0011 0.0004 0.0036
Echinococcus granulosus carbonyl reductase 1 0.0088 0.0111 0.0431
Echinococcus multilocularis carbonyl reductase 1 0.0088 0.0111 0.0431
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0011 0.0004 0.0032
Echinococcus granulosus bloom syndrome protein 0.0041 0.0046 0.0174
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Echinococcus multilocularis carbonyl reductase 1 0.0088 0.0111 0.0431
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0376 0.0516 0.0816
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.0033 0.0049
Echinococcus granulosus retinol dehydrogenase 11 0.0088 0.0111 0.0431
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0009 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0111 0.2115
Echinococcus granulosus FTZ F1 alpha 0.0054 0.0064 0.0244
Echinococcus granulosus dnaJ subfamily B 0.024 0.0325 0.1283
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.0376 0.0516 1
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Onchocerca volvulus 0.0065 0.008 0.1501
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0088 0.0111 0.0184
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0063 0.1177
Echinococcus multilocularis multidrug resistance associated protein 7 0.0011 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0044
Brugia malayi hypothetical protein 0.0296 0.0404 0.0404
Brugia malayi RE18450p 0.0376 0.0516 0.0516
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.0033 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.2115
Schistosoma mansoni hypothetical protein 0.0112 0.0145 0.0229
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0088 0.0111 0.2115
Loa Loa (eye worm) carbonic anhydrase 3 0.0297 0.0405 0.0641
Leishmania major protein kinase, putative 0.0024 0.0021 0.0369
Leishmania major hypothetical protein, conserved 0.0088 0.0111 0.2115
Echinococcus multilocularis bifunctional heparan sulfate 0.0012 0.0004 0.0009
Plasmodium falciparum carbonic anhydrase 0.0153 0.0203 0.3909
Brugia malayi sodium-independent organic anion transporter family protein 0.0073 0.009 0.009
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0321
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0088 0.0111 0.2108
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0024 0.0021 0.0369
Trypanosoma brucei short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0376 0.0516 0.0516
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0007 0.0097
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0016 0.0025
Echinococcus granulosus single minded 2 0.0065 0.008 0.0308
Onchocerca volvulus 0.0054 0.0064 0.1187
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0083 0.0105 0.1999
Echinococcus granulosus carbonic anhydrase 0.0153 0.0203 0.0797
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Trypanosoma cruzi short chain dehydrogenase, putative 0.0088 0.0111 0.2115
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0083
Trypanosoma brucei oxidoreductase-like protein 0.0088 0.0111 0.2115
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0083 0.0105 0.1999
Schistosoma mansoni inositol monophosphatase 0.0038 0.0041 0.0065
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0376 0.0516 0.2038
Brugia malayi MAP kinase sur-1 0.0083 0.0105 0.0105
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0184
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.0064 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0111 0.0184
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0032 0.0033 0.0053
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0058 0.0058
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Schistosoma mansoni transcription factor LCR-F1 0.003 0.0031 0.0048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Mycobacterium tuberculosis Possible thiamine biosynthesis oxidoreductase ThiO 0.0376 0.0516 0.0883
Brugia malayi hypothetical protein 0.0218 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Brugia malayi MH2 domain containing protein 0.0101 0.013 0.013
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Loa Loa (eye worm) MH2 domain-containing protein 0.0101 0.013 0.0206
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Echinococcus multilocularis lamin 0.0028 0.0027 0.0098
Brugia malayi RNA binding protein 0.0233 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0376 0.0516 0.0816
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0376 0.0516 0.0813
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0028 0.0028
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0088 0.0111 0.2115
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0064 0.0064
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0028 0.0102
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0068 0.026
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.0033 0.0049
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0024 0.0037
Echinococcus granulosus geminin 0.0611 0.0847 0.3351
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0023 0.002 0.0071
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0088 0.0111 0.0172
Mycobacterium ulcerans arylsulfatase AtsB 0.0218 0.0294 0.0462
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0004 0.0031
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0058 0.1083
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0064 0.0064
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0105 0.0166
Onchocerca volvulus 0.0073 0.009 0.1709
Brugia malayi cDNA sequence BC016226 0.0376 0.0516 0.0516
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Echinococcus granulosus retinol dehydrogenase 11 0.0088 0.0111 0.0431
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Brugia malayi EGF-like domain containing protein 0.0025 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0042
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0011 0.0003 0.0002
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.0033 0.0049
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0054 0.0054
Mycobacterium ulcerans putative regulatory protein 0.0065 0.008 0.0123
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0008 0.0111
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Echinococcus multilocularis retinol dehydrogenase 11 0.0088 0.0111 0.0431
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0033 0.005
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0003
Brugia malayi steroid hormone receptor 0.0054 0.0064 0.0064
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0111 0.2115
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0008 0.0117
Echinococcus multilocularis serotonin transporter 0.0062 0.0075 0.029
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.0313 0.1233
Schistosoma mansoni rab6-interacting 0.002 0.0016 0.0026
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0088 0.0111 0.2115
Onchocerca volvulus 0.002 0.0016 0.0266
Mycobacterium ulcerans arylsulfatase AtsD 0.0218 0.0294 0.0462
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0016 0.0056
Loa Loa (eye worm) oxidoreductase 0.0088 0.0111 0.0175
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0111 0.2115
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0376 0.0516 0.0816
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0088 0.0111 0.0144
Loa Loa (eye worm) hypothetical protein 0.0039 0.0043 0.0068
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0032 0.03
Loa Loa (eye worm) agrin synaptic family protein 0.005 0.0058 0.0091
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.0064 0.0101
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0032 0.0033 0.0609
Schistosoma mansoni polycystin 1-related 0.002 0.0016 0.0026
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.0033 0.0049
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0011 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.0064 0.0064
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Leishmania major 3-keto-dihydrosphingosine reductase 0.0088 0.0111 0.2115
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0016 0.002
Echinococcus granulosus carbonic anhydrase 0.0153 0.0203 0.0797
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Mycobacterium ulcerans oxidoreductase 0.0088 0.0111 0.0172
Schistosoma mansoni DNA helicase recq5 0.0028 0.0028 0.0044
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0011 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0153 0.0203 0.0321
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0088 0.0111 0.2115
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0046 0.0046
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0041 0.0062
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0032 0.0033 0.0124
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0027 0.0042
Plasmodium falciparum amino acid transporter, putative 0.0011 0.0003 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0033 0.005
Brugia malayi TAR-binding protein 0.0233 0.0315 0.0315
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0153 0.0203 0.0203
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Onchocerca volvulus Putative organic anion transporter 0.0073 0.009 0.1709
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Echinococcus granulosus follistatin 0.005 0.0058 0.0221
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.0033 0.0049
Trypanosoma cruzi short chain dehydrogenase, putative 0.0088 0.0111 0.2115
Giardia lamblia Hypothetical protein 0.0218 0.0294 0.5389
Onchocerca volvulus 0.0073 0.009 0.1709
Schistosoma mansoni cpg binding protein 0.0018 0.0013 0.002
Echinococcus granulosus Ankyrin 0.0015 0.0009 0.0026
Mycobacterium leprae Possible thiamine biosynthesis oxidoreductase ThiO 0.0376 0.0516 0.0787
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0016 0.0056
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0083 0.0105 0.1999
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0044
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0024 0.0085
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0009 0.0025
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0032 0.0572
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0016 0.0264
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.0064 0.0101
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0024 0.0085
Brugia malayi Cytochrome P450 family protein 0.0063 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.002 0.0016 0.0026
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.0033 0.0606
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.0064 0.0244
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.0064 0.0244
Echinococcus multilocularis mitogen activated protein kinase 3 0.0083 0.0105 0.0407
Mycobacterium ulcerans short-chain dehydrogenase 0.0088 0.0111 0.0172
Echinococcus granulosus bifunctional heparan sulfate 0.0012 0.0004 0.0009
Onchocerca volvulus 0.0088 0.0111 0.2108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.0544 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1043 0.1454 0.1454
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0016 0.025
Leishmania major pteridine reductase 1 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0062 0.0075 0.0119
Echinococcus multilocularis transfer RNA-Lys 0.0065 0.008 0.0308
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.0064 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.0064 0.0101
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0024 0.0021 0.0369
Entamoeba histolytica hypothetical protein 0.003 0.0031 0.0526
Giardia lamblia Hypothetical protein 0.0218 0.0294 0.5389
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Schistosoma mansoni inositol transporter 0.0032 0.0033 0.0053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0011 0.0003 0.0004
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.006 0.0095
Echinococcus multilocularis thyroid hormone receptor alpha 0.0054 0.0064 0.0244
Onchocerca volvulus Sepiapterin reductase homolog 0.0088 0.0111 0.2108
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0088 0.0111 0.0144
Schistosoma mansoni fad oxidoreductase 0.0376 0.0516 0.0816
Echinococcus granulosus solute carrier family 5 0.0032 0.0033 0.0124
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0024 0.0085
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0032 0.0572
Brugia malayi latrophilin 2 splice variant baaae 0.0241 0.0327 0.0327
Mycobacterium ulcerans short-chain type oxidoreductase 0.0088 0.0111 0.0172
Echinococcus multilocularis steroid dehydrogenase 0.0088 0.0111 0.0431
Brugia malayi CXXC zinc finger family protein 0.0017 0.0012 0.0012
Brugia malayi Sulfotransferase domain containing protein 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0023 0.002 0.034
Brugia malayi hypoxia-induced factor 1 0.0273 0.0372 0.0372
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0353 0.0484 0.0765
Onchocerca volvulus 0.0088 0.0111 0.2108
Onchocerca volvulus 0.0088 0.0111 0.2108
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0033 0.005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0376 0.0516 0.9486
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0376 0.0516 0.2038
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0033 0.005
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0376 0.0516 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.0039 0.0043 0.0067
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0042 0.0779
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.002 0.0083
Echinococcus granulosus high affinity choline transporter 1 0.0294 0.0402 0.1585
Trypanosoma brucei short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0033 0.005
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0016 0.0025
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0376 0.0516 1
Echinococcus multilocularis oxidoreductase 0.0088 0.0111 0.0431
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0088 0.0111 0.2115
Mycobacterium ulcerans thiamine biosynthesis oxidoreductase ThiO 0.0376 0.0516 0.0813
Schistosoma mansoni hypothetical protein 0.0112 0.0145 0.0229
Trichomonas vaginalis steroid dehydrogenase, putative 0.0088 0.0111 0.1801
Schistosoma mansoni tar DNA-binding protein 0.0233 0.0315 0.0498
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0376 0.0516 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0064 0.0101
Schistosoma mansoni tar DNA-binding protein 0.0233 0.0315 0.0498
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Brugia malayi ecdysteroid receptor 0.0054 0.0064 0.0064
Schistosoma mansoni blooms syndrome DNA helicase 0.0014 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0054 0.0064 0.0101
Brugia malayi Latrophilin receptor protein 2 0.0112 0.0145 0.0145
Schistosoma mansoni lamin 0.0028 0.0027 0.0042
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0184
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0028 0.0028
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.0064 0.0101
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0011 0.0003 0.0009
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0153 0.0203 0.0203
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0016 0.0056
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0088 0.0111 0.2115
Mycobacterium ulcerans arylsulfatase AtsD 0.0218 0.0294 0.0462
Onchocerca volvulus 0.0088 0.0111 0.2108
Schistosoma mansoni follistatin 0.005 0.0058 0.0091
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0321
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0032 0.0033 0.0124
Echinococcus granulosus tumor protein p63 0.0266 0.0362 0.1426
Treponema pallidum fructose-bisphosphate aldolase 0.0395 0.0544 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0016 0.0264
Onchocerca volvulus Putative organic anion transporter 0.0073 0.009 0.1709
Toxoplasma gondii transporter, major facilitator family protein 0.0073 0.009 0.1717
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Schistosoma mansoni cytochrome P450 0.0032 0.0033 0.0053
Leishmania major DNA polymerase kappa, putative 0.002 0.0016 0.0264
Mycobacterium ulcerans sulfatase 0.0218 0.0294 0.0462
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0088 0.0111 0.1801
Onchocerca volvulus 0.0088 0.0111 0.2108
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0111 0.2115
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.005 0.0058 0.0091
Loa Loa (eye worm) hypothetical protein 0.3289 0.461 0.7293
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0188 0.0252 0.0395
Echinococcus granulosus sodium:glucose cotransporter 0.0032 0.0033 0.0124
Schistosoma mansoni steroid dehydrogenase 0.0088 0.0111 0.0175
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0058 0.0058
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.0064 0.0244
Mycobacterium ulcerans glycolipid sulfotransferase 0.0012 0.0004 0.0004
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0376 0.0516 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0011 0.0003 0.0004
Schistosoma mansoni DNA helicase recq1 0.0028 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0294 0.0402 0.0635
Schistosoma mansoni multidrug resistance protein 0.0011 0.0004 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Brugia malayi laminin-like protein K08C7.3 precursor 0.0025 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0111 0.0184
Echinococcus granulosus dna polymerase eta 0.002 0.0016 0.0054
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0088 0.0111 0.0431
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0036
Leishmania major cytochrome p450-like protein 0.0053 0.0063 0.1177
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0376 0.0516 0.0816
Echinococcus multilocularis sodium and chloride dependent glycine 0.0011 0.0003 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0032 0.0033 0.0595
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0009
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0184
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0014
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0073 0.009 0.035
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0111 0.2115
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0023 0.002 0.0349
Loa Loa (eye worm) hypoxia-induced factor 1 0.0273 0.0372 0.0588
Schistosoma mansoni hypothetical protein 0.024 0.0325 0.0515
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0376 0.0516 0.9486
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0016 0.0021
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0088 0.0111 0.2115
Echinococcus multilocularis Ankyrin 0.0015 0.0009 0.0026
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Echinococcus granulosus lamin 0.0028 0.0027 0.0098
Entamoeba histolytica short chain dehydrogenase family protein 0.0088 0.0111 0.2006
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0073 0.009 0.035
Onchocerca volvulus 0.0088 0.0111 0.2108
Echinococcus granulosus GPCR family 2 0.0112 0.0145 0.0565
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0063 0.0099
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0016 0.0264
Schistosoma mansoni inositol monophosphatase 0.0038 0.0041 0.0065
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0012 0.0004 0.0007
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0184
Echinococcus multilocularis carbonyl reductase 1 0.0088 0.0111 0.0431
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0041 0.0483
Schistosoma mansoni tar DNA-binding protein 0.0233 0.0315 0.0498
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0046 0.0572
Echinococcus multilocularis tar DNA binding protein 0.0233 0.0315 0.1241
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0012 0.0004 0.0007
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.0064 0.0101
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0297 0.0405 0.7847
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0063 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0294 0.5268
Loa Loa (eye worm) hypothetical protein 0.0088 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0073 0.009 0.0143
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0016 0.0264
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Leishmania major dehydrogenase-like protein 0.0088 0.0111 0.2115
Brugia malayi hypothetical protein 0.0073 0.009 0.009
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0033 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0028 0.0028
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.0064 0.0101
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.0064 0.0064
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0064 0.0064
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0094 0.0366
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.2115
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0011 0.0004 0.0032
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0016 0.0264
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0037
Brugia malayi hypothetical protein 0.002 0.0016 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Echinococcus multilocularis carbonic anhydrase 0.0153 0.0203 0.0797
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0193 0.0259 0.0407
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0088 0.0111 0.2115
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0834 0.116 0.4595
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0028 0.0499
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0297 0.0405 0.7847
Loa Loa (eye worm) hypothetical protein 0.0231 0.0313 0.0495
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0088 0.0111 0.2108
Echinococcus granulosus hypothetical protein 0.0088 0.0111 0.0431
Schistosoma mansoni short chain dehydrogenase 0.0088 0.0111 0.0175
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0184
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.0064 0.1187
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0028 0.0102
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0024 0.0085
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0088 0.0111 0.2011
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0153 0.0203 0.0321
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0111 0.2115
Leishmania major hypothetical protein, conserved 0.0088 0.0111 0.2115
Toxoplasma gondii protease inhibitor PI2 0.005 0.0058 0.1083
Leishmania major short chain dehydrogenase, putative 0.0088 0.0111 0.2115
Mycobacterium ulcerans short chain dehydrogenase 0.0088 0.0111 0.0172
Plasmodium vivax amine transporter, putative 0.0011 0.0003 0.0009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0088 0.0111 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0083
Schistosoma mansoni multidrug resistance protein 0.0011 0.0004 0.0006
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.0064 0.0244
Trypanosoma brucei multidrug resistance protein E 0.0011 0.0004 0.0032
Brugia malayi bHLH-PAS transcription factor 0.0065 0.008 0.008
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0088 0.0111 0.0184
Echinococcus granulosus agrin 0.005 0.0058 0.0221
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.0064 0.0244
Echinococcus multilocularis dna polymerase kappa 0.002 0.0016 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0111 0.2115
Echinococcus granulosus serotonin transporter 0.0062 0.0075 0.029
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0111 0.0111
Brugia malayi RNA recognition motif domain containing protein 0.0233 0.0315 0.0315
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0376 0.0516 0.0516
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0016 0.0264
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0088 0.0111 0.0175
Leishmania major quinonoid dihydropteridine reductase 0.0088 0.0111 0.2115
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0091
Toxoplasma gondii aldehyde dehydrogenase 0.0051 0.006 0.1128
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0046 0.0174
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0024 0.0407
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0004

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = -9.1 Binding affinity, displacement of [125I]-iodosulpride from human Dopamine receptor D3 expressed in CHO cells ChEMBL. No reference
Ki (binding) = -8.1 Binding affinity, displacement of [125I]-iodosulpride from human Dopamine receptor D2 expressed in CHO cells ChEMBL. No reference
Log Ki (binding) = 8.1 Binding affinity, displacement of [125I]-iodosulpride from human Dopamine receptor D2 expressed in CHO cells ChEMBL. No reference
Log Ki (binding) = 9.1 Binding affinity, displacement of [125I]-iodosulpride from human Dopamine receptor D3 expressed in CHO cells ChEMBL. No reference
Ratio (binding) = 10 Ratio of D3 receptor to the D2 receptor ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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