Detailed information for compound 592820

Basic information

Technical information
  • TDR Targets ID: 592820
  • Name: SR-01000633472-1
  • MW: 322.242 | Formula: C14H9F3N4O2
  • H donors: 2 H acceptors: 3 LogP: 2.62 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc2c(c1)non2)Nc1cccc(c1)C(F)(F)F
  • InChi: 1S/C14H9F3N4O2/c15-14(16,17)8-2-1-3-9(6-8)18-13(22)19-10-4-5-11-12(7-10)21-23-20-11/h1-7H,(H2,18,19,22)
  • InChiKey: CNHQACZJTANFKQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • KM 09750
  • ZINC00171097

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Isocitrate dehydrogenase 0.0026 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis calcium activated potassium channel 0.0028 0.0009 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0093 0.0058 0.0074
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0009 0.0012
Schistosoma mansoni amine GPCR 0.0756 0.0552 0.1442
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0055 0.0142
Echinococcus granulosus calcium activated potassium channel 0.0028 0.0009 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0074 0.0094
Echinococcus granulosus neuropeptide receptor 0.0756 0.0552 0.0712
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0093 0.0058 0.0074
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0093 0.0058 0.0066
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0026 0.0007 0.0009
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0048 0.0024 0.0673
Echinococcus granulosus biogenic amine 5HT receptor 0.5146 0.3823 0.4934
Brugia malayi PHD-finger family protein 0.003 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0006 0.0123
Loa Loa (eye worm) beta-lactamase 0.0027 0.0009 0.001
Trypanosoma brucei cAMP response protein 1, putative 0.0048 0.0024 0.0028
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0 0.0005
Trypanosoma cruzi Emopamil binding protein, putative 0.0285 0.0201 0.0232
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0048 0.0024 0.0062
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.009 0.0055 0.0071
Loa Loa (eye worm) LGC-31 protein 0.0093 0.0058 0.0066
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0093 0.0058 0.0066
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0048 0.0024 0.0556
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0048 0.0024 0.0062
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0007 0.0009
Leishmania major hypothetical protein, conserved 0.0028 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Mycobacterium ulcerans lipase LipD 0.0027 0.0009 0.0191
Brugia malayi putative neuropeptide receptor 0.0756 0.0552 0.0552
Brugia malayi Receptor family ligand binding region containing protein 0.0168 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0028 0.0009 0.0024
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0037 0.0016 0.0353
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0097 0.006 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0645 0.0469 0.0605
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0083 0.0217
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0013 0.0249
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.009 0.0055 0.0071
Onchocerca volvulus 0.0019 0.0002 0.0005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0061 0.0034 0.0039
Echinococcus multilocularis importin subunit beta 1 0.0042 0.002 0.0025
Brugia malayi G-protein coupled receptor 0.0756 0.0552 0.0552
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0061 0.0034 0.0941
Trypanosoma brucei importin beta-1 subunit, putative 0.0042 0.002 0.0023
Echinococcus granulosus lamin dm0 0.0026 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Echinococcus granulosus GPCR family 2 0.0117 0.0076 0.0097
Echinococcus granulosus sodium and chloride dependent glycine 0.171 0.1262 0.1629
Schistosoma mansoni ryanodine receptor related 0.0028 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni opsin-like receptor 0.0756 0.0552 0.1442
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Loa Loa (eye worm) hypothetical protein 0.5225 0.3881 0.4493
Brugia malayi Inositol-1 0.0036 0.0015 0.0015
Toxoplasma gondii NADPH-glutathione reductase 0.0061 0.0034 0.0941
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0285 0.0201 0.0232
Schistosoma mansoni neuropeptide f receptor 76f 0.0756 0.0552 0.1442
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0037 0.0016 0.0353
Echinococcus granulosus TGF beta signal transducer SmadC 0.0021 0.0004 0.0004
Leishmania major hypothetical protein, unknown function 0.0048 0.0024 0.0028
Mycobacterium tuberculosis Probable esterase LipL 0.0027 0.0009 0.0191
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0028 0.0559
Trypanosoma cruzi DNA topoisomerase II, putative 0.002 0.0003 0.0004
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0037 0.0016 0.0353
Trichomonas vaginalis bromodomain-containing protein, putative 0.0033 0.0013 0.0246
Trypanosoma cruzi Flagellar Member 6 0.0048 0.0024 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Echinococcus granulosus glycoprotein Antigen 5 0.0028 0.0009 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus granulosus Niemann Pick C1 protein 0.0153 0.0102 0.0132
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0048 0.0024 0.0476
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Echinococcus granulosus g protein coupled receptor 0.0756 0.0552 0.0712
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0048 0.0024 0.0031
Echinococcus granulosus somatostatin receptor 0.0756 0.0552 0.0712
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Echinococcus multilocularis neuropeptide receptor 0.0756 0.0552 0.0712
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) neuropeptide F receptor 0.0756 0.0552 0.0638
Plasmodium vivax SET domain protein, putative 0.0089 0.0055 0.1526
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.011 0.007 0.007
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0028 0.0009 0.0011
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0002 0.0005
Mycobacterium leprae Probable lipase LipE 0.0027 0.0009 0.0256
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0037 0.0016 0.0353
Treponema pallidum catabolite gene activator 0.0049 0.0025 0.0225
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0045 0.0893
Brugia malayi Probable DNA topoisomerase II 0.0025 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0048 0.0024 0.0556
Brugia malayi Cytochrome P450 family protein 0.0074 0.0043 0.0043
Schistosoma mansoni glutamate receptor AMPA 0.0477 0.0344 0.0899
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0002 0.0005
Schistosoma mansoni zinc finger protein 0.0025 0.0007 0.0017
Echinococcus multilocularis Niemann Pick C1 protein 0.0107 0.0068 0.0087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0009 0.0024
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0028 0.0009 0.0009
Loa Loa (eye worm) RGC/RGC protein kinase 0.0168 0.0113 0.0131
Echinococcus granulosus serotonin transporter 0.1464 0.1079 0.1392
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0093 0.0058 0.0074
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0034 0.0013 0.026
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0034 0.0013 0.026
Echinococcus granulosus voltage gated hydrogen channel 1 0.0028 0.0009 0.0012
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) cytochrome P450 0.0037 0.0016 0.0018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0045 0.0022 0.0022
Echinococcus multilocularis conserved hypothetical protein 0.8254 0.6138 0.7923
Schistosoma mansoni amine GPCR 0.2342 0.1733 0.4534
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0028 0.0009 0.0012
Loa Loa (eye worm) ryanodine receptor 0.0028 0.0009 0.001
Echinococcus granulosus G protein coupled receptor 139 0.0756 0.0552 0.0712
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0003 0.0004
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0028 0.0009 0.0012
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0048 0.0024 0.0673
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0756 0.0552 0.1442
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0083 0.0217
Loa Loa (eye worm) hypothetical protein 0.0493 0.0355 0.0411
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0026 0.0066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Echinococcus granulosus g protein coupled receptor 0.0756 0.0552 0.0712
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0017 0.0331
Onchocerca volvulus 0.0028 0.0009 0.0026
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0031 0.0011 0.0014
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0034 0.0013 0.026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0093 0.0058 0.0058
Brugia malayi MH2 domain containing protein 0.0306 0.0216 0.0216
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0048 0.0024 0.0673
Leishmania major mitochondrial DNA topoisomerase II 0.0025 0.0007 0.0008
Brugia malayi MH2 domain containing protein 0.0021 0.0004 0.0004
Brugia malayi nuclear hormone receptor 0.0019 0.0002 0.0002
Echinococcus multilocularis chromobox protein 1 0.0068 0.0039 0.005
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0009 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0037 0.0016 0.0353
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0756 0.0552 0.0712
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0007 0.013
Giardia lamblia O-linked GlcNAc transferase 0.0027 0.0008 0.1277
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0024 0.0062
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.001
Schistosoma mansoni smad1 5 8 and 0.0021 0.0004 0.0009
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0026 0.0007 0.02
Entamoeba histolytica DNA topoisomerase II, putative 0.0025 0.0007 0.0594
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0093 0.0058 0.015
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0025 0.0007 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Echinococcus granulosus neuropeptide Y receptor 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0077 0.0045 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0002 0.0002
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.0166
Brugia malayi neuropeptide F receptor 0.0756 0.0552 0.0552
Brugia malayi Trypsin-like protease protein 5 0.0028 0.0009 0.0009
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0043 0.002 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0002 0.0046
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0026 0.0007 0.02
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0756 0.0552 0.0712
Brugia malayi acetyltransferase, GNAT family protein 0.0105 0.0067 0.0067
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0756 0.0552 0.1442
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0011 0.0212
Brugia malayi CHE-14 protein 0.0046 0.0023 0.0023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0004 0.0348
Echinococcus granulosus tar DNA binding protein 0.0128 0.0083 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0009 0.001
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.009 0.0055 0.0064
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0645 0.0469 0.0605
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0105 0.0067 0.0173
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0002 0.0005
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0031 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0493 0.0355 0.0411
Echinococcus multilocularis zinc finger protein 0.0025 0.0007 0.0009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0001
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0048 0.0024 0.0476
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0043 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0093 0.0058 0.0074
Loa Loa (eye worm) hypothetical protein 0.1447 0.1066 0.1234
Echinococcus granulosus transient receptor potential cation channel 0.0028 0.0009 0.0012
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0028
Mycobacterium leprae Conserved hypothetical protein 0.0037 0.0016 0.0472
Schistosoma mansoni lipoxygenase 0.008 0.0048 0.0124
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0093 0.0058 0.0058
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0037 0.0016 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.1551 0.1144 0.1476
Brugia malayi hypothetical protein 0.0067 0.0038 0.0038
Brugia malayi Egg laying defective protein 4 0.0048 0.0024 0.0024
Onchocerca volvulus 0.0093 0.0058 0.0163
Echinococcus multilocularis sodium channel protein 0.0028 0.0009 0.0012
Entamoeba histolytica hypothetical protein 0.0077 0.0046 0.3993
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0164 0.0111 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0048 0.0024 0.0068
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Trypanosoma cruzi cAMP binding protein, putative 0.0048 0.0024 0.0028
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0048 0.0024 0.0556
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0048 0.0024 0.0062
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0043 0.002 0.0026
Echinococcus granulosus atrial natriuretic peptide receptor 0.0168 0.0113 0.0146
Mycobacterium tuberculosis Probable reductase 0.0402 0.0288 0.669
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.009 0.0055 0.4876
Trypanosoma brucei cytochrome P450, putative 0.0074 0.0043 0.005
Brugia malayi cytochrome P450 0.0037 0.0016 0.0016
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0025 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni smad 0.0021 0.0004 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0001 0.0004
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0037 0.0016 0.0353
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Echinococcus granulosus short transient receptor potential channel 6 0.0029 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0038 0.0017 0.0042
Echinococcus granulosus expressed protein 0.0031 0.0012 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.4718 0.3504 0.4056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0002 0.0002
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.002 0.0003 0.0008
Loa Loa (eye worm) ACC-1 protein 0.0093 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0001 0.0004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0174 0.0118 0.2737
Echinococcus granulosus ryanodine receptor 44f 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0038 0.0017 0.0017
Echinococcus granulosus histone lysine methyltransferase setb 0.0106 0.0067 0.0086
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0009 0.001
Echinococcus granulosus neuropeptide receptor 0.0756 0.0552 0.0712
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0048 0.0024 0.0476
Echinococcus granulosus tissue type plasminogen activator 0.0038 0.0017 0.0021
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.002 0.0003 0.0004
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0028 0.0009 0.0009
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0025 0.0007 0.0007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.0085 0.0221
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0015 0.0017
Echinococcus multilocularis orexin receptor type 2 0.0756 0.0552 0.0712
Echinococcus granulosus two pore calcium channel protein 1 0.0028 0.0009 0.0012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0019 0.0053
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0031 0.0012 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.1464 0.1079 0.2822
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0001 0.0001
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0031 0.0011 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0027 0.0009 0.0167
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus granulosus cGMP dependent protein kinase 1 0.0048 0.0024 0.0031
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0028 0.0009 0.0024
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0048 0.0024 0.0028
Echinococcus granulosus microtubule associated protein 2 0.14 0.1032 0.1331
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.002 0.0051
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0756 0.0552 0.1442
Brugia malayi GnHR receptor homolog 0.0756 0.0552 0.0552
Loa Loa (eye worm) GABA receptor subunit 0.005 0.0026 0.0029
Onchocerca volvulus 0.0493 0.0355 0.1013
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0097 0.006 0.007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0002 0.0002
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0322 0.0228 0.0294
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0037 0.0016 0.0353
Schistosoma mansoni pyruvate kinase 0.0033 0.0013 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0002 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0061 0.0034 0.0087
Mycobacterium tuberculosis Conserved protein 0.0027 0.0009 0.0191
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0756 0.0552 0.0712
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0002 0.0002
Echinococcus granulosus smad 0.0021 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0042 0.0821
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0037 0.0016 0.0353
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0006 0.0165
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0756 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0451 0.0325 0.0375
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0756 0.0552 0.1574
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0048 0.0024 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Leishmania major extracellular receptor, putative 0.0168 0.0113 0.0131
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0048 0.0024 0.0476
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0645 0.0469 0.0605
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Onchocerca volvulus Arrow homolog 0.0029 0.001 0.0027
Schistosoma mansoni opsin-like receptor 0.0756 0.0552 0.1442
Toxoplasma gondii target of rapamycin (TOR), putative 0.0067 0.0038 0.1068
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Mycobacterium tuberculosis Probable dehydrogenase 0.0402 0.0288 0.669
Schistosoma mansoni lipoxygenase 0.0114 0.0074 0.0191
Trichomonas vaginalis adenylate cyclase type III, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) CYP4Cod1 0.0074 0.0043 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0112 0.2202
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0756 0.0552 0.0712
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0402 0.0288 0.8958
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0001 0.0013
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0002 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0007 0.0144
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0015 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0341 0.0243 0.4783
Loa Loa (eye worm) isocitrate dehydrogenase 0.0026 0.0007 0.0008
Giardia lamblia DNA topoisomerase II 0.0023 0.0005 0.0846
Echinococcus multilocularis sex peptide receptor 0.0756 0.0552 0.0712
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0002 0.0002
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0048 0.0024 0.0673
Echinococcus multilocularis neuropeptide Y receptor 0.0756 0.0552 0.0712
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0026 0.0026
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0493 0.0355 0.0411
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0493 0.0355 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0034 0.0039
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.037 0.0264 0.0305
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0006
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0061 0.0034 0.0039
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.005 0.0026 0.0026
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0168 0.0113 0.0146
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0005 0.0438
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0046 0.0022 0.3633
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0011
Toxoplasma gondii O-linked N-acetylglucosamine transferase 0.0027 0.0008 0.0216
Echinococcus multilocularis g protein coupled receptor 0.0756 0.0552 0.0712
Brugia malayi voltage-dependent calcium channel 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0322 0.0228 0.0294
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0493 0.0355 0.0929
Loa Loa (eye worm) voltage-gated potassium channel 0.0092 0.0057 0.0066
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0112 0.2202
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0028 0.0073
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0013 0.0015
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0593 0.043 0.3983
Schistosoma mansoni vesicular acetylcholine transporter 0.4718 0.3504 0.9166
Loa Loa (eye worm) hypothetical protein 0.0321 0.0228 0.0263
Echinococcus multilocularis potassium large conductance calcium activated 0.0028 0.0009 0.0012
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Brugia malayi Sodium:neurotransmitter symporter family protein 0.171 0.1262 0.1262
Echinococcus multilocularis cpg binding protein 0.0065 0.0037 0.0047
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0034 0.0013 0.026
Plasmodium falciparum DNA gyrase subunit A 0.0087 0.0053 0.1477
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0106 0.0067 0.0174
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0034 0.0014 0.0271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Onchocerca volvulus 0.0756 0.0552 0.1574
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0037 0.0016 0.0353
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0077 0.0045 0.0118
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0053 0.0027 0.0631
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0046 0.0022 0.0508
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0001 0.0001
Echinococcus multilocularis voltage dependent calcium channel 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.3107 0.2304 0.2666
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0102 0.0065 0.0083
Onchocerca volvulus 0.0756 0.0552 0.1574
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0025 0.0007 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0756 0.0552 0.0552
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0016 0.0018
Onchocerca volvulus Putative nachr subunit 0.0093 0.0058 0.0163
Echinococcus granulosus nmda type glutamate receptor 0.1568 0.1156 0.1492
Echinococcus granulosus metabotropic glutamate receptor 2 0.0168 0.0113 0.0146
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0004 0.0111
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0077 0.0045 0.0058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0004 0.0005
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Brugia malayi Importin beta-1 subunit 0.0042 0.002 0.002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Brugia malayi beta-lactamase 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0756 0.0552 0.1574
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0083 0.0096
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0107 0.0068 0.0068
Echinococcus multilocularis g protein coupled receptor 0.0756 0.0552 0.0712
Giardia lamblia GTOR 0.009 0.0055 0.9169
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0117 0.0076 0.0097
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0009 0.0012
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0341 0.0243 0.4783
Brugia malayi Trypsin family protein 0.0028 0.0009 0.0009
Brugia malayi ORL1-like opioid receptor 0.0756 0.0552 0.0552
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni ATP-binding cassette transporter 0.0477 0.0344 0.0899
Onchocerca volvulus 0.0067 0.0038 0.0108
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0045 0.0893
Echinococcus multilocularis receptor type guanylyl cyclase 0.0168 0.0113 0.0146
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0493 0.0355 0.0929
Echinococcus granulosus nAChR subunit 0.005 0.0026 0.0033
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0093 0.0058 0.0058
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0097 0.006 0.1191
Echinococcus multilocularis netrin receptor unc 5 0.002 0.0003 0.0004
Onchocerca volvulus 0.0285 0.0201 0.0572
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0048 0.0024 0.0031
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0008 0.0009
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0002 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0077 0.0045 0.0118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.001
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0004 0.0004
Echinococcus granulosus shaker cognate 0.0028 0.0009 0.0012
Loa Loa (eye worm) inositol-1 0.0036 0.0015 0.0017
Schistosoma mansoni hypothetical protein 0.0077 0.0046 0.0118
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0006 0.0467
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0756 0.0552 0.0638
Echinococcus multilocularis NMDA receptor 0.0322 0.0228 0.0294
Echinococcus multilocularis microtubule associated protein 2 0.14 0.1032 0.1331
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0002 0.0005
Entamoeba histolytica protein kinase rad3, putative 0.0017 0.0001 0.0056
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0034 0.0039
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0063 0.0164
Brugia malayi nuclear receptor NHR-88 0.0019 0.0002 0.0002
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0028 0.0009 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0033 0.0013 0.0343
Echinococcus multilocularis short transient receptor potential channel 6 0.0028 0.0009 0.0012
Echinococcus granulosus neuropeptide Y receptor 0.0756 0.0552 0.0712
Onchocerca volvulus 0.0253 0.0177 0.0504
Schistosoma mansoni biogenic amine receptor 0.0756 0.0552 0.1442
Brugia malayi hypothetical protein 0.0043 0.002 0.002
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0028 0.0009 0.0011
Echinococcus granulosus single minded 2 0.0034 0.0013 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.024 0.0167 0.3289
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.1185 0.0871 0.1008
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0031 0.0011 0.1848
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0007 0.013
Brugia malayi ecdysteroid receptor 0.0019 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0009 0.0232
Schistosoma mansoni voltage-gated potassium channel 0.011 0.007 0.0183
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0009 0.0024
Echinococcus multilocularis snurportin 1 0.0451 0.0325 0.0418
Echinococcus granulosus nuclear factor of activated T cells 5 0.0102 0.0065 0.0083
Schistosoma mansoni hypothetical protein 0.0048 0.0024 0.0062
Loa Loa (eye worm) neuropeptide F receptor 0.0756 0.0552 0.0638
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Plasmodium falciparum DNA gyrase subunit B 0.0046 0.0022 0.0615
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0493 0.0355 0.0355
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0645 0.0469 0.0605
Onchocerca volvulus 0.0493 0.0355 0.1013
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.037 0.0264 0.0264
Schistosoma mansoni hypothetical protein 0.002 0.0003 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0009 0.0167
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0756 0.0552 0.0712
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0011 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0042 0.0821
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0028 0.0009 0.0011
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Schistosoma mansoni rab6-interacting 0.0019 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0019
Echinococcus multilocularis serotonin transporter 0.1464 0.1079 0.1392
Toxoplasma gondii hypothetical protein 0.0493 0.0355 1
Chlamydia trachomatis pyruvate kinase 0.0033 0.0013 0.0287
Brugia malayi Dopamine receptor protein 2 0.0756 0.0552 0.0552
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0645 0.0469 0.0605
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0048 0.0024 0.0024
Loa Loa (eye worm) glutamate receptor 0.0168 0.0113 0.0131
Trypanosoma brucei glucosidase, putative 0.0026 0.0007 0.0008
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0074 0.0043 0.1003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0042 0.002 0.0023
Mycobacterium tuberculosis Conserved protein 0.0048 0.0024 0.0556
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Echinococcus granulosus snurportin 1 0.0451 0.0325 0.0418
Toxoplasma gondii transporter, cation channel family protein 0.0028 0.0009 0.0254
Echinococcus multilocularis mothers against decapentaplegic 5 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0037 0.0016 0.0353
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0034 0.0089
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0007 0.0144
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0004 0.0091
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0036 0.0047
Brugia malayi Doublecortin family protein 0.0019 0.0003 0.0003
Treponema pallidum sodium- and chloride- dependent transporter 0.1464 0.1079 1
Mycobacterium leprae Conserved hypothetical protein 0.0048 0.0024 0.0744
Toxoplasma gondii hypothetical protein 0.0028 0.0009 0.0254
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus multilocularis transient receptor potential cation channel 0.0028 0.0009 0.0012
Mycobacterium leprae putative cytochrome p450 0.0037 0.0016 0.0472
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0015 0.0018
Schistosoma mansoni myosin xvIII 0.0756 0.0552 0.1442
Loa Loa (eye worm) latrophilin receptor protein 2 0.0117 0.0076 0.0087
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0048 0.0024 0.0556
Onchocerca volvulus 0.0028 0.0009 0.0026
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0031 0.0011 0.0013
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0028 0.0009 0.0012
Schistosoma mansoni histamine h1 receptor 0.0756 0.0552 0.1442
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.009 0.0055 0.0055
Echinococcus granulosus nmda type glutamate receptor 0.082 0.0599 0.0773
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0087 0.0053 0.8725
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0048 0.0024 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0011 0.0212
Onchocerca volvulus 0.0026 0.0008 0.0022
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0004 0.0654
Loa Loa (eye worm) hypothetical protein 0.0038 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Echinococcus granulosus histone acetyltransferase KAT2B 0.0033 0.0013 0.0016
Echinococcus granulosus hypothetical protein 0.901 0.6702 0.865
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0002 0.0002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0015 0.0294
Schistosoma mansoni importin beta-1 0.0042 0.002 0.0051
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0028
Echinococcus multilocularis transmembrane protease serine 3 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1091 0.0802 0.0927
Echinococcus multilocularis g protein coupled receptor 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0033 0.0013 0.0246
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0053 0.0028 0.2449
Echinococcus multilocularis enteropeptidase 0.0028 0.0009 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.171 0.1262 0.3301
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.002 0.0051
Plasmodium vivax DNA topoisomerase II, putative 0.0025 0.0007 0.0189
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0002 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0756 0.0552 0.0712
Echinococcus multilocularis allatostatin A receptor 0.0756 0.0552 0.0712
Echinococcus multilocularis fibrillin 1 0.0029 0.001 0.0012
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0004 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.14 0.1032 0.2698
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.037 0.0264 0.034
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0026 0.0007 0.0009
Trypanosoma brucei DNA topoisomerase ii 0.0025 0.0007 0.0008
Echinococcus granulosus sex peptide receptor 0.0756 0.0552 0.0712
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0447 0.0321 0.7468
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0048 0.0024 0.0062
Echinococcus granulosus hypothetical protein 0.0028 0.0009 0.0012
Chlamydia trachomatis DNA gyrase subunit B 0.0046 0.0022 0.0508
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0093 0.0058 0.0058
Plasmodium falciparum glutathione reductase 0.0176 0.012 0.3358
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0028 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0011 0.0013
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0009 0.0012
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0048 0.0024 0.0062
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0282 0.0198 0.0517
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Toxoplasma gondii peptidylprolyl isomerase 0.0031 0.0011 0.0302
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0015 0.0017
Echinococcus multilocularis tumor protein p63 0.0368 0.0262 0.0338
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0004 0.0091
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0048 0.0024 0.0028
Schistosoma mansoni cpg binding protein 0.0059 0.0033 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0002 0.0002
Trichomonas vaginalis set domain proteins, putative 0.0697 0.0507 1
Leishmania major hypothetical protein, conserved 0.0285 0.0201 0.0232
Schistosoma mansoni alpha-1 adrenergic receptor 0.0756 0.0552 0.1442
Brugia malayi Bromodomain containing protein 0.008 0.0048 0.0048
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0402 0.0288 0.669
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.0022
Brugia malayi CHD4 protein 0.0016 0.0001 0.0001
Brugia malayi Trypsin family protein 0.0028 0.0009 0.0009
Echinococcus multilocularis laminin 0.0029 0.001 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0007 0.0144
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0037 0.0016 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0023 0.0443
Trichomonas vaginalis glucosylceramidase, putative 0.024 0.0167 0.3289
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0034 0.0014 0.0271
Schistosoma mansoni tyrosine kinase 0.0168 0.0113 0.0296
Schistosoma mansoni hypothetical protein 0.0117 0.0076 0.0197
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0001 0.0021
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0013 0.0385
Echinococcus multilocularis lysosomal alpha glucosidase 0.0116 0.0074 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0002 0.0005
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.001 0.0264
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0077 0.0045 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Loa Loa (eye worm) glutamate receptor 1 0.0477 0.0344 0.0398
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Schistosoma mansoni o-linked n-acetylglucosamine transferase ogt 0.0027 0.0008 0.0021
Schistosoma mansoni acetylcholine receptor-related 0.0043 0.002 0.0052
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0011
Brugia malayi CXXC zinc finger family protein 0.0059 0.0033 0.0033
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0093 0.0058 0.0066
Onchocerca volvulus 0.01 0.0063 0.0178
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0009 0.0012
Leishmania major cytochrome p450-like protein 0.0037 0.0016 0.0018
Echinococcus granulosus peptide allatostatin:somatostatin 0.0756 0.0552 0.0712
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0027 0.0009 0.0191
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0493 0.0355 0.0458
Echinococcus multilocularis ryanodine receptor 44f 0.0028 0.0009 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Mycobacterium ulcerans hypothetical protein 0.0028 0.0009 0.0209
Toxoplasma gondii HEAT repeat-containing protein 0.0042 0.002 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0483
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0002 0.0002
Loa Loa (eye worm) acetylcholine receptor protein 0.0043 0.002 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0093 0.0058 0.0058
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0034 0.0013 0.026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.002 0.0025
Brugia malayi neuropeptide F receptor 0.0756 0.0552 0.0552
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0007 0.0144
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0093 0.0058 0.0074
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0013 0.0287
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0028 0.0009 0.0009
Brugia malayi Calcitonin receptor-like protein seb-1 0.0371 0.0264 0.0264
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0371 0.0264 0.0264
Echinococcus multilocularis g-protein coupled receptor 0.0756 0.0552 0.0712
Trichomonas vaginalis glutamate synthase, putative 0.0016 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Mycobacterium tuberculosis Probable lipase LipD 0.0027 0.0009 0.0191
Mycobacterium ulcerans hypothetical protein 0.0027 0.0009 0.0191
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0493 0.0355 0.0458
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0493 0.0355 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis two pore calcium channel protein 1 0.0028 0.0009 0.0012
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0002 0.0002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0026 0.0007 0.0623
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0024 0.0062
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0055 0.1526
Trichomonas vaginalis rotamase, putative 0.0031 0.0011 0.0217
Brugia malayi hypothetical protein 0.0232 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.0046 0.0898
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0002 0.0002
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0028 0.0009 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0009
Mycobacterium ulcerans regulatory protein 0.0048 0.0024 0.0556
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0168 0.0113 0.0131
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0033 0.0013 0.0343
Echinococcus granulosus neuropeptide s receptor 0.095 0.0696 0.0898
Brugia malayi Glycosyl hydrolases family 31 protein 0.0116 0.0074 0.0074
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0011 0.095
Giardia lamblia Histone acetyltransferase GCN5 0.0028 0.0009 0.1427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0028 0.0551
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0041 0.0019 0.0582
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0033 0.0656
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0093 0.0058 0.0058
Onchocerca volvulus 0.1464 0.1079 0.3078
Toxoplasma gondii hypothetical protein 0.0493 0.0355 1
Onchocerca volvulus 0.0043 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0282 0.0198 0.0229
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0008 0.0009
Schistosoma mansoni amine GPCR 0.0756 0.0552 0.1442
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0028 0.0009 0.0009
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0034 0.0013 0.026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0756 0.0552 0.1442
Brugia malayi excitatory GABA receptor EXP-1A 0.0093 0.0058 0.0058
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0013 0.0014
Echinococcus granulosus Niemann Pick C1 protein 0.0107 0.0068 0.0087
Loa Loa (eye worm) hypothetical protein 0.1185 0.0871 0.1008
Trichomonas vaginalis maltase-glucoamylase, putative 0.0026 0.0007 0.0144
Toxoplasma gondii isocitrate dehydrogenase 0.0026 0.0007 0.02
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0037 0.0016 0.0353
Echinococcus multilocularis tissue type plasminogen activator 0.0038 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0117 0.0076 0.0087
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0055 0.0064
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.009 0.0055 0.4876
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0011 0.0013
Trichomonas vaginalis adenylate cyclase type III, putative 0.0034 0.0013 0.026
Brugia malayi beta-lactamase family protein 0.0027 0.0009 0.0009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0756 0.0552 0.0712
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus multilocularis nmda type glutamate receptor 0.1568 0.1156 0.1492
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0043 0.005
Schistosoma mansoni ap endonuclease 0.0021 0.0004 0.001
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Brugia malayi latrophilin 2 splice variant baaae 0.0253 0.0177 0.0177
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0027 0.0009 0.0191
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0028 0.0009 0.0012
Brugia malayi hypothetical protein 0.0043 0.002 0.002
Onchocerca volvulus 0.0047 0.0024 0.0066
Onchocerca volvulus 0.0756 0.0552 0.1574
Trichomonas vaginalis ran, putative 0.0031 0.0011 0.0224
Brugia malayi hypothetical protein 0.0077 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.2229 0.1649 0.1909
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0046 0.0022 0.0202
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0031 0.0011 0.0013
Plasmodium falciparum DNA topoisomerase 2 0.0025 0.0007 0.0189
Onchocerca volvulus 0.003 0.0011 0.003
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0756 0.0552 0.1442
Schistosoma mansoni neurotransmitter gated ion channel 0.0043 0.002 0.0052
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0 0.0005
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0593 0.043 1
Echinococcus granulosus importin subunit beta 1 0.0042 0.002 0.0025
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0077 0.0045 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0756 0.0552 0.0712
Echinococcus granulosus glycine receptor subunit alpha 1 0.0093 0.0058 0.0074
Onchocerca volvulus 0.0093 0.0058 0.0163
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0028 0.0009 0.0012
Trypanosoma brucei cAMP binding protein, putative 0.0048 0.0024 0.0028
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0093 0.0058 0.0074
Loa Loa (eye worm) AGC/PKG protein kinase 0.0048 0.0024 0.0028
Leishmania major pyruvate kinase 0.0033 0.0013 0.0015
Schistosoma mansoni coup transcription factor 0.0019 0.0002 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0006 0.0006
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.002 0.0023
Echinococcus multilocularis two pore calcium channel protein 2 0.0028 0.0009 0.0012
Echinococcus granulosus transient receptor potential cation channel 0.0028 0.0009 0.0012
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0074 0.0094
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel protein 0.0028 0.0009 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0019 0.0374
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0756 0.0552 0.0638
Echinococcus granulosus Tolloid protein 1 0.0029 0.001 0.0012
Echinococcus multilocularis neuropeptide receptor A26 0.095 0.0696 0.0898
Echinococcus multilocularis protein patched 0.0046 0.0023 0.0029
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0009 0.0012
Loa Loa (eye worm) voltage-dependent calcium channel 0.0028 0.0009 0.001
Brugia malayi Cyclic-nucleotide gated cation channel 0.0077 0.0045 0.0045
Echinococcus multilocularis pyruvate kinase 0.0033 0.0013 0.0016
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0034 0.0013 0.026
Trichomonas vaginalis apoptosis inducing factor, putative 0.0016 0 0.0005
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0037 0.0016 0.0353
Echinococcus multilocularis vesicular acetylcholine transporter 0.4718 0.3504 0.4522
Trypanosoma cruzi extracellular receptor, putative 0.0168 0.0113 0.0131
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni netrin receptor unc5 0.002 0.0003 0.0007
Echinococcus multilocularis transient receptor potential cation channel 0.0028 0.0009 0.0012
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0048 0.0024 0.3973
Trypanosoma cruzi importin beta-1 subunit, putative 0.0034 0.0014 0.0016
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0034 0.0039
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0493 0.0355 0.0929
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0006 0.0165
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0001 0.0001
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0001 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Echinococcus multilocularis transient receptor potential cation channel 0.0028 0.0009 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0004 0.0083
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0756 0.0552 0.0712
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0003 0.0003
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0756 0.0552 0.0552
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0015 0.0017
Brugia malayi chromobox protein homolog 3 0.0038 0.0017 0.0017
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0253 0.0177 0.0462
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.001 0.0264
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0289 0.0755
Echinococcus granulosus voltage dependent calcium channel 0.0028 0.0009 0.0012
Echinococcus granulosus bloom syndrome protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0013 0.0015
Brugia malayi larval opioid receptor 0.0756 0.0552 0.0552
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0037 0.0016 0.0353
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0026 0.0007 0.0019
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0015 0.0019
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0013 0.0014
Brugia malayi vesicular acetylcholine transporter unc-17 0.4718 0.3504 0.3504
Entamoeba histolytica hypothetical protein 0.0168 0.0113 1
Echinococcus granulosus neuropeptides capa receptor 0.0756 0.0552 0.0712
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0048 0.0024 0.0031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0001 0.0001
Leishmania major trypanothione reductase 0.0176 0.012 0.0138
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0006
Brugia malayi hypothetical protein 0.0168 0.0113 0.0113
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0023 0.0029
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0043 0.002 0.0026
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0048 0.0024 0.0673
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Echinococcus granulosus netrin receptor unc 5 0.002 0.0003 0.0004
Brugia malayi cation channel family protein 0.0028 0.0009 0.0009
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0493 0.0355 0.0458
Brugia malayi beta-lactamase family protein 0.0027 0.0009 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0026 0.0007 0.0623
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1635 0.1206 0.1556
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0168 0.0113 0.0146
Trichomonas vaginalis glucosylceramidase, putative 0.024 0.0167 0.3289
Brugia malayi hypothetical protein 0.0164 0.0111 0.0111
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0756 0.0552 0.1442
Loa Loa (eye worm) hypothetical protein 0.0054 0.0028 0.0032
Leishmania major C-8 sterol isomerase-like protein 1.161 0.8639 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0037 0.0016 0.0353
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0013 0.0014
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0004 0.0005
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Echinococcus granulosus glycine receptor subunit alpha 1 0.0093 0.0058 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Brugia malayi putative neuropeptide receptor NPR1 0.0756 0.0552 0.0552
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0034 0.0013 0.0015
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0077 0.0045 0.0058
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0322 0.0228 0.0294
Onchocerca volvulus 0.005 0.0026 0.0072
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0009 0.001
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0007 0.0009
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.002 0.0003 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0027 0.0009 0.0022
Toxoplasma gondii exonuclease III APE 0.0021 0.0004 0.0111
Echinococcus granulosus Ankyrin 0.002 0.0003 0.0004
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Entamoeba histolytica hypothetical protein 0.005 0.0026 0.2233
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0026 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Onchocerca volvulus 0.0023 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus granulosus neuropeptide receptor A26 0.095 0.0696 0.0898
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.024 0.0167 0.0193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0027 0.0009 0.0022
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0322 0.0228 0.0294
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0402 0.0288 0.669
Entamoeba histolytica hypothetical protein 0.0077 0.0046 0.3993
Echinococcus granulosus laminin 0.0029 0.001 0.0012
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0039 0.0045
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.002 0.0025
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0116 0.0074 0.0086
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0055 0.1092
Loa Loa (eye worm) hypothetical protein 0.0067 0.0038 0.0044
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0061 0.0034 0.0778
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0093 0.0058 0.0066
Giardia lamblia Pyruvate kinase 0.0033 0.0013 0.2053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1464 0.1079 0.2822
Schistosoma mansoni amine GPCR 0.0756 0.0552 0.1442
Loa Loa (eye worm) hypothetical protein 0.011 0.007 0.0081
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0065 0.0037 0.0095
Echinococcus granulosus cytochrome P450 2K1 0.0037 0.0016 0.002
Chlamydia trachomatis DNA gyrase subunit A 0.0087 0.0053 0.1221
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0026 0.0007 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0046 0.0058
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0072 0.0042 0.0048
Echinococcus multilocularis isocitrate dehydrogenase 0.0026 0.0007 0.0009
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0009 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0083 0.0217
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0756 0.0552 0.0712
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0105 0.0067 0.0086
Loa Loa (eye worm) hypothetical protein 0.0107 0.0068 0.0078
Brugia malayi Uncoordinated protein 44 0.002 0.0003 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0015 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0026 0.0007 0.0009
Toxoplasma gondii transporter, cation channel family protein 0.0028 0.0009 0.0254
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0036 0.0047
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0048 0.0024 0.0673
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0645 0.0469 0.0605
Brugia malayi Heterochromatin protein 1 0.0068 0.0039 0.0039
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0061 0.0034 0.0034
Echinococcus granulosus potassium large conductance calcium activated 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0083 0.0217
Schistosoma mansoni alpha-glucosidase 0.01 0.0062 0.0162
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0029 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0055
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0048 0.0024 0.0062
Brugia malayi Serotonin/octopamine receptor family protein 7 0.269 0.1992 0.1992
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0078 0.2193
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0007 0.013
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0117 0.0076 0.0197
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0756 0.0552 0.0712
Brugia malayi Thioredoxin reductase 0.0176 0.012 0.012
Onchocerca volvulus 0.0026 0.0008 0.0022
Echinococcus multilocularis glutamate receptor 2 0.0645 0.0469 0.0605
Loa Loa (eye worm) trypsin family protein 0.0028 0.0009 0.001
Plasmodium vivax amine transporter, putative 0.0493 0.0355 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Onchocerca volvulus 0.0756 0.0552 0.1574
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.1464 0.1079 0.1249
Echinococcus granulosus glycine receptor subunit beta 0.0093 0.0058 0.0074
Onchocerca volvulus 0.0756 0.0552 0.1574
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0013 0.0015
Loa Loa (eye worm) norepinephrine transporter 0.1464 0.1079 0.1249
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0055
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Echinococcus multilocularis beta LACTamase domain containing family member 0.0027 0.0009 0.0011
Onchocerca volvulus 0.0697 0.0507 0.1447
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0093 0.0058 0.0074
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0009 0.0254
Echinococcus granulosus beta LACTamase domain containing family member 0.0027 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni hypothetical protein 0.0665 0.0484 0.1265
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Onchocerca volvulus 0.0756 0.0552 0.1574
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0028 0.0009 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0037 0.0016 0.0353
Brugia malayi metabotropic glutamate receptor type 2 0.0168 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0034 0.0013 0.026
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0593 0.043 1
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0002 0.0002
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0028 0.0009 0.0009
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0015 0.0412
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Echinococcus granulosus allatostatin A receptor 0.0756 0.0552 0.0712
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0043 0.002 0.002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0002 0.0002
Leishmania major regulatory subunit of protein kinase a-like protein 0.0048 0.0024 0.0028
Echinococcus granulosus tm gpcr rhodopsin 0.1635 0.1206 0.1556
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0009 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0077 0.0045 0.0058
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0011 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0026 0.0007 0.0009
Echinococcus multilocularis Smad4 0.0021 0.0004 0.0004
Loa Loa (eye worm) voltage-gated calcium channel 0.0028 0.0009 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Schistosoma mansoni inositol monophosphatase 0.0036 0.0015 0.0038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0061 0.0034 0.0778
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0004 0.0071
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0028 0.0009 0.0012
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0093 0.0058 0.0058
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0055 0.007
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0043 0.005
Brugia malayi N-terminal motif family protein 0.0048 0.0024 0.0024
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0034 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.002 0.002
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0028 0.0009 0.0012
Schistosoma mansoni protein kinase 0.0168 0.0113 0.0296
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis voltage dependent calcium channel 0.0028 0.0009 0.0012
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0015 0.2432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0011 0.0011
Echinococcus granulosus chromobox protein 1 0.0068 0.0039 0.005
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0046 0.0058
Mycobacterium leprae conserved hypothetical protein 0.0027 0.0009 0.0256
Schistosoma mansoni nAChR subunit 0.0043 0.002 0.0052
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0493 0.0355 0.0355
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0093 0.0058 0.0066
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.009 0.0055 0.0064
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0093 0.0058 0.0074
Schistosoma mansoni DNA topoisomerase II 0.0025 0.0007 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0001 0.0018
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0048 0.0024 0.0024
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0028 0.0009 0.0011
Treponema pallidum cyclic nucleotide binding protein 0.0048 0.0024 0.0221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Echinococcus granulosus lamin 0.0026 0.0008 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Echinococcus granulosus short transient receptor potential channel 6 0.0028 0.0009 0.0012
Echinococcus granulosus 7tm_1 domain containing protein 0.0756 0.0552 0.0712
Plasmodium vivax hypothetical protein, conserved 0.0493 0.0355 1
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0493 0.0355 0.0458
Trypanosoma brucei DNA topoisomerase II beta, putative 0.002 0.0003 0.0004
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.024 0.0167 0.3289
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0011 0.0012
Brugia malayi hypothetical protein 0.0028 0.0009 0.0009
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus multilocularis serotonin receptor 0.3107 0.2304 0.2973
Echinococcus granulosus sodium channel protein 0.0028 0.0009 0.0012
Echinococcus granulosus vesicular acetylcholine transporter 0.4718 0.3504 0.4522
Schistosoma mansoni ran 0.0031 0.0011 0.0029
Entamoeba histolytica acetyltransferase, GNAT family 0.0028 0.0009 0.0759
Echinococcus granulosus transmembrane protease serine 3 0.0028 0.0009 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Echinococcus granulosus RUN 0.0019 0.0003 0.0003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0006 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.0756 0.0552 0.0712
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0028 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0447 0.0321 0.7468
Treponema pallidum cyclic nucleotide binding protein 0.0048 0.0024 0.0221
Echinococcus multilocularis smad 0.0021 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Brugia malayi Cation transporter family protein 0.0093 0.0058 0.0058
Onchocerca volvulus 0.0027 0.0009 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0028 0.0559
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0029 0.001 0.0011
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0322 0.0228 0.0294
Plasmodium vivax thioredoxin reductase, putative 0.0176 0.012 0.3358
Echinococcus granulosus potassium voltage gated channel subfamily H 0.037 0.0264 0.034
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0037 0.0016 0.0353
Schistosoma mansoni neuropeptide F-like receptor 0.0756 0.0552 0.1442
Echinococcus granulosus alpha 1A adrenergic receptor 0.0756 0.0552 0.0712
Leishmania major hypothetical protein, unknown function 0.0028 0.0009 0.0011
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0034 0.0013 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.024 0.0167 0.3289
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0004 0.0071
Echinococcus multilocularis neuropeptide FF receptor 2 0.0756 0.0552 0.0712
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0028 0.0009 0.0024
Mycobacterium ulcerans transcriptional regulatory protein 0.0048 0.0024 0.0556
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0121 0.0078 0.01
Schistosoma mansoni tyrosine kinase 0.0168 0.0113 0.0296
Toxoplasma gondii isocitrate dehydrogenase 0.0026 0.0007 0.02
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.024 0.0167 0.0167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.002 0.0051
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0097 0.006 0.5318
Schistosoma mansoni biogenic amine receptor 0.0756 0.0552 0.1442
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0017 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0026 0.0008 0.001
Trichomonas vaginalis sucrase-isomaltase, putative 0.0026 0.0007 0.0144
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0006 0.0123
Echinococcus granulosus histone acetyltransferase KAT2B 0.01 0.0063 0.0081
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0002 0.0038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0002 0.0002
Echinococcus multilocularis potassium voltage gated channel protein 0.0028 0.0009 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0001 0.0018
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0322 0.0228 0.0294
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0001 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0093 0.0058 0.0058
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0097 0.006 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0003 0.0003
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0028
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0048 0.0024 0.0031
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1464 0.1079 0.1249
Schistosoma mansoni sodium/chloride dependent transporter 0.171 0.1262 0.3301
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0002 0.0059
Schistosoma mansoni hypothetical protein 0.0756 0.0552 0.1442
Loa Loa (eye worm) hypothetical protein 0.0106 0.0067 0.0077
Echinococcus multilocularis O glycosyltransferase 0.0027 0.0008 0.001
Echinococcus granulosus receptor type guanylyl cyclase 0.0168 0.0113 0.0146
Brugia malayi G protein-coupled receptor 0.0756 0.0552 0.0552
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0061 0.0034 0.0778
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0028 0.0009 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0006 0.0006
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0093 0.0058 0.015
Schistosoma mansoni lamin 0.0026 0.0008 0.002
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0043 0.005
Echinococcus granulosus dro:myosuppressin receptor 0.0756 0.0552 0.0712
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0011 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0002 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0756 0.0552 0.1442
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0038
Entamoeba histolytica hypothetical protein 0.0034 0.0014 0.1191
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Schistosoma mansoni pyruvate kinase 0.0033 0.0013 0.0032
Schistosoma mansoni hypothetical protein 0.0322 0.0228 0.0597
Schistosoma mansoni 60S ribosomal protein L21 0.0062 0.0034 0.0089
Plasmodium falciparum cGMP-dependent protein kinase 0.0048 0.0024 0.0673
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0048 0.0024 0.0673
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0493 0.0355 0.0929
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Schistosoma mansoni metabotropic glutamate receptor 0.0168 0.0113 0.0296
Mycobacterium tuberculosis Probable lipase LipE 0.0027 0.0009 0.0191
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Echinococcus multilocularis 0.0037 0.0016 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0011 0.0212
Loa Loa (eye worm) hypothetical protein 0.1464 0.1079 0.1249
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.269 0.1992 0.2306
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0009 0.0167
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0002 0.0005
Onchocerca volvulus 0.0054 0.0028 0.008
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0006 0.0123
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0018
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0097 0.006 0.007
Echinococcus granulosus transient receptor potential cation channel 0.0028 0.0009 0.0012
Echinococcus granulosus transient receptor potential cation channel 0.0028 0.0009 0.0012
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0093 0.0058 0.0074
Brugia malayi Cation transporter family protein 0.0093 0.0058 0.0058
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0093 0.0058 0.015
Echinococcus multilocularis dnaJ subfamily B 0.0665 0.0484 0.0624
Loa Loa (eye worm) hypothetical protein 0.0371 0.0264 0.0306
Schistosoma mansoni cpg binding protein 0.0065 0.0037 0.0095
Echinococcus granulosus zinc finger protein 0.0025 0.0007 0.0009
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0028 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0117 0.0076 0.0197
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) melatonin receptor type 1A 0.0756 0.0552 0.0638
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0002 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0009 0.0024
Echinococcus multilocularis potassium voltage gated channel protein 0.0028 0.0009 0.0012
Schistosoma mansoni voltage-gated cation channel 0.0028 0.0009 0.0024
Onchocerca volvulus 0.0048 0.0024 0.0068
Loa Loa (eye worm) hypothetical protein 0.0077 0.0045 0.0052
Giardia lamblia NADH oxidase lateral transfer candidate 0.0061 0.0034 0.556
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0034 0.556
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0097 0.006 0.007
Schistosoma mansoni glutamate receptor kainate 0.0477 0.0344 0.0899
Trichomonas vaginalis penicillin-binding protein, putative 0.0027 0.0009 0.0167
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0034 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Schistosoma mansoni alpha glucosidase 0.0026 0.0007 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Schistosoma mansoni loxhd1 0.0019 0.0003 0.0006
Mycobacterium tuberculosis Conserved protein 0.0027 0.0009 0.0191
Schistosoma mansoni metabotropic glutamate receptor 0.0168 0.0113 0.0296
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0161 0.0208
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0 0.0005
Brugia malayi Protein kinase domain containing protein 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0037 0.0016 0.004
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Brugia malayi ion channel NompC 0.0028 0.0009 0.0009
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0493 0.0355 0.0929
Schistosoma mansoni biogenic amine (5HT) receptor 0.5146 0.3823 1
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.001 0.0012
Echinococcus granulosus sodium and chloride dependent glycine 0.171 0.1262 0.1629
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0493 0.0355 0.0929
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0028 0.0009 0.0012
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0048 0.0024 0.0028
Echinococcus granulosus neuropeptides capa receptor 0.0756 0.0552 0.0712
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0371 0.0264 0.0306
Echinococcus multilocularis sodium leak channel non selective protein 0.0028 0.0009 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0037 0.0016 0.0353
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0048 0.0024 0.0031
Loa Loa (eye worm) RGC/RGC protein kinase 0.0168 0.0113 0.0131
Schistosoma mansoni patched 1 0.0046 0.0023 0.0058
Brugia malayi TAR-binding protein 0.0128 0.0083 0.0083
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0493 0.0355 0.0458
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0037 0.0016 0.0353
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0002 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0756 0.0552 0.1442
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0493 0.0355 0.0929
Loa Loa (eye worm) TK/ROR protein kinase 0.0038 0.0017 0.0019
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0011 0.0013
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0037 0.0016 0.0353
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0006 0.0123
Loa Loa (eye worm) hypothetical protein 0.0232 0.0161 0.0186
Brugia malayi ERG2 and Sigma1 receptor like protein 1.161 0.8639 0.8639
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0093 0.0058 0.0074
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0168 0.0113 0.0131
Trypanosoma brucei Emopamil binding protein, putative 0.0285 0.0201 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0002 0.0002
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0025 0.0007 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0117 0.0076 0.0076
Echinococcus granulosus geminin 0.0373 0.0266 0.0343
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Leishmania major alpha glucosidase II subunit, putative 0.0026 0.0007 0.0008
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0004 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0093 0.0058 0.015
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0039 0.0773
Echinococcus granulosus pyruvate kinase 0.0033 0.0013 0.0016
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Echinococcus multilocularis pyruvate kinase 0.0026 0.0008 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0003 0.0003
Echinococcus multilocularis voltage gated potassium channel 0.011 0.007 0.009
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0028 0.0009 0.0026
Entamoeba histolytica hypothetical protein 0.0017 0.0001 0.0056
Treponema pallidum catabolite gene activator (Crp) 0.0048 0.0024 0.0221
Mycobacterium ulcerans esterase/lipase LipP 0.0027 0.0009 0.0191
Leishmania major protein kinase, putative 0.0048 0.0024 0.0028
Leishmania major GTP-binding protein, putative 0.0031 0.0011 0.0013
Mycobacterium ulcerans hypothetical protein 0.0023 0.0006 0.0123
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.005 0.0026 0.0066
Toxoplasma gondii transporter, cation channel family protein 0.0028 0.0009 0.0254
Schistosoma mansoni hypothetical protein 0.0451 0.0325 0.0848
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0004 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.0306 0.0216 0.025
Onchocerca volvulus 0.0168 0.0113 0.0323
Leishmania major DNA topoisomerase ii 0.002 0.0003 0.0004
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0011 0.0012
Echinococcus granulosus cGMP dependent protein kinase 1 0.0048 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0164 0.0111 0.0128
Brugia malayi follicle stimulating hormone receptor 0.1091 0.0802 0.0802
Echinococcus multilocularis neutral alpha glucosidase AB 0.0026 0.0007 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0756 0.0552 0.0552
Schistosoma mansoni transient receptor potential channel 0.0028 0.0009 0.0024
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Echinococcus granulosus transient receptor potential cation channel 0.0028 0.0009 0.0012
Echinococcus multilocularis expressed protein 0.0031 0.0012 0.0015
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0026 0.0007 0.0166
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0048 0.0024 0.0031
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0289 0.0755
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.269 0.1992 0.2306
Brugia malayi G protein-coupled receptor F59B2.13 0.0756 0.0552 0.0552
Echinococcus granulosus GTP binding nuclear protein Ran 0.0031 0.0011 0.0014
Loa Loa (eye worm) voltage-gated potassium channel 0.0028 0.0009 0.001
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0001 0.0025
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.001 0.0012
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0028 0.0009 0.0024
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0028 0.0009 0.0012
Onchocerca volvulus 0.0756 0.0552 0.1574
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0024 0.0476
Schistosoma mansoni hypothetical protein 0.002 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni hypothetical protein 0.0373 0.0266 0.0695
Plasmodium falciparum pyruvate kinase 0.0033 0.0013 0.0348
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0028 0.0009 0.0009
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0117 0.0076 0.0097
Echinococcus granulosus hyperpolarization activated cyclic 0.0077 0.0045 0.0058
Brugia malayi Fibulin-1 precursor 0.0029 0.001 0.001
Plasmodium falciparum thioredoxin reductase 0.0176 0.012 0.3358
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni pyruvate kinase 0.0017 0.0001 0.0001
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0028 0.0009 0.0012
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.171 0.1262 0.1461
Echinococcus multilocularis Mastin 0.0028 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0756 0.0552 0.1442
Echinococcus granulosus 7TM GPCR rhodopsin 0.0756 0.0552 0.0712
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0048 0.0024 0.0062
Schistosoma mansoni glutamate receptor AMPA 0.0477 0.0344 0.0899
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0042 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0001 0.0018
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0402 0.0288 0.669
Brugia malayi RNA binding protein 0.0128 0.0083 0.0083
Entamoeba histolytica hypothetical protein 0.0077 0.0046 0.3993
Brugia malayi olfactory channel protein osm-9 0.0029 0.001 0.001
Echinococcus granulosus fmrfamide receptor 0.0756 0.0552 0.0712
Brugia malayi hypothetical protein 0.0043 0.002 0.002
Trypanosoma cruzi DNA topoisomerase II, putative 0.002 0.0003 0.0004
Brugia malayi RE15519p 0.0756 0.0552 0.0552
Echinococcus multilocularis glycine receptor subunit beta 0.0093 0.0058 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0015 0.0294
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.002 0.0003 0.0003
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0756 0.0552 0.1442
Brugia malayi Cytochrome P450 family protein 0.0037 0.0016 0.0016
Schistosoma mansoni ran 0.0031 0.0011 0.0029
Trypanosoma brucei Flagellar Member 6 0.0048 0.0024 0.0028
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0011 0.0013
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.009 0.0055 0.0064
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0013 0.0348
Chlamydia trachomatis DNA gyrase subunit B 0.0046 0.0022 0.0508
Loa Loa (eye worm) serotonin transporter b 0.1464 0.1079 0.1249
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0031 0.0012 0.0013
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0493 0.0355 0.0411
Echinococcus granulosus neuropeptide FF receptor 2 0.0756 0.0552 0.0712
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0034 0.0013 0.026
Leishmania major hypothetical protein, conserved 0.0027 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Loa Loa (eye worm) solute carrier family 6 member 4 0.1464 0.1079 0.1249
Toxoplasma gondii ABC1 family protein 0.0027 0.0009 0.0232
Echinococcus granulosus intermediate filament protein 0.0026 0.0008 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0482
Schistosoma mansoni Smad4 0.0021 0.0004 0.0009
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0028 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.001
Trichomonas vaginalis adenylate cyclase type, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0011
Plasmodium falciparum amino acid transporter, putative 0.0493 0.0355 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0093 0.0058 0.0074
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0029 0.001 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0048 0.0024 0.0556
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0002 0.0002
Plasmodium falciparum histone acetyltransferase GCN5 0.0028 0.0009 0.0242
Brugia malayi MH2 domain containing protein 0.0021 0.0004 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0756 0.0552 0.1442
Echinococcus multilocularis GPCR, family 2 0.0117 0.0076 0.0097
Echinococcus multilocularis lamin 0.0026 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Onchocerca volvulus 0.0093 0.0058 0.0163
Echinococcus granulosus death domain containing protein 0.002 0.0003 0.0004
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0077 0.0045 0.0118
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0077 0.0045 0.0118
Schistosoma mansoni biogenic amine (5HT) receptor 0.3107 0.2304 0.6026
Brugia malayi hypothetical protein 0.0756 0.0552 0.0552
Onchocerca volvulus 0.0038 0.0017 0.0046
Schistosoma mansoni neuropeptide receptor 0.0756 0.0552 0.1442
Brugia malayi Pre-SET motif family protein 0.0089 0.0055 0.0055
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0083 0.0096
Loa Loa (eye worm) RGC/RGC protein kinase 0.0168 0.0113 0.0131
Brugia malayi Glycosyl hydrolases family 31 protein 0.0026 0.0007 0.0007
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0006 0.0467
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0002 0.0002
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0031 0.0011 0.0313
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0253 0.0177 0.0205
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0093 0.0058 0.0074
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Schistosoma mansoni transient receptor potential channel 4 0.0028 0.0009 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0077 0.0045 0.0058
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0028 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0117 0.0076 0.0197
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0037 0.0016 0.0353
Schistosoma mansoni alpha-glucosidase 0.01 0.0062 0.0162
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0077 0.0045 0.0058
Trypanosoma cruzi Emopamil binding protein, putative 0.0285 0.0201 0.0232
Brugia malayi hypothetical protein 0.0043 0.002 0.002
Brugia malayi MH1 domain containing protein 0.0021 0.0004 0.0004
Schistosoma mansoni voltage-dependent calcium channel 0.0028 0.0009 0.0024
Echinococcus granulosus hyperpolarization activated cyclic 0.0077 0.0045 0.0058
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0026 0.0007 0.0198
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0025 0.0007 0.0019
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0015 0.0294
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.0756 0.0552 0.0712
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0033 0.0013 0.0343
Echinococcus multilocularis thioredoxin glutathione reductase 0.0177 0.012 0.0155
Trypanosoma cruzi trypanothione reductase, putative 0.0061 0.0034 0.0039
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0756 0.0552 0.0712
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0007 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0106 0.0067 0.0174
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0002 0.0002
Schistosoma mansoni neuropeptide receptor 0.0756 0.0552 0.1442
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0011 0.0012
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0028 0.0009 0.0024
Plasmodium falciparum importin beta, putative 0.0042 0.002 0.0547
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0645 0.0469 0.0605
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0009 0.0024
Echinococcus granulosus pyruvate kinase 0.0033 0.0013 0.0016
Schistosoma mansoni opsin-like receptor 0.0756 0.0552 0.1442
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0037 0.0016 0.0018
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0493 0.0355 0.0458
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0026 0.0026
Plasmodium vivax DNA gyrase subunit B, putative 0.0046 0.0022 0.0615
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0002 0.0002
Schistosoma mansoni glutamate receptor kainate 0.0477 0.0344 0.0899
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Onchocerca volvulus 0.0093 0.0058 0.0163
Echinococcus granulosus two pore calcium channel protein 2 0.0028 0.0009 0.0012
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0021 0.0004 0.0009
Onchocerca volvulus 0.0028 0.0009 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0037 0.0016 0.0353
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0011 0.0013
Brugia malayi Cytochrome P450 family protein 0.0074 0.0043 0.0043
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0028 0.0009 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0002 0.0005
Echinococcus granulosus orexin receptor type 2 0.0756 0.0552 0.0712
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0043 0.002 0.0023
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0282 0.0198 0.0517
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0028 0.0009 0.0024
Echinococcus granulosus thioredoxin glutathione reductase 0.0177 0.012 0.0155
Brugia malayi Smad1 0.0021 0.0004 0.0004
Schistosoma mansoni cytochrome P450 0.0037 0.0016 0.004
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0048 0.0024 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.0045 0.0118
Entamoeba histolytica hypothetical protein 0.0077 0.0046 0.3993
Leishmania major protein kinase A regulatory subunit, putative 0.0048 0.0024 0.0028
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0003 0.0003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0002 0.0005
Echinococcus multilocularis nmda type glutamate receptor 0.082 0.0599 0.0773
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0048 0.0024 0.0673
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0004 0.0005
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0756 0.0552 0.1442
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0001 0.0021
Echinococcus multilocularis Niemann Pick C1 protein 0.0153 0.0102 0.0132
Mycobacterium tuberculosis Conserved hypothetical protein 0.0048 0.0024 0.0556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0007 0.013
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0031 0.0011 0.0313
Mycobacterium ulcerans hypothetical protein 0.0048 0.0024 0.0556
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0048 0.0024 0.0068
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0117 0.0076 0.0097
Trypanosoma cruzi cAMP response protein 1 0.0048 0.0024 0.0028
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0093 0.0058 0.0074
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0007 0.0018
Brugia malayi Dopamine receptor protein 1 0.1447 0.1066 0.1066
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0028 0.0009 0.0012
Echinococcus granulosus tumor protein p63 0.0368 0.0262 0.0338
Onchocerca volvulus 0.0756 0.0552 0.1574
Schistosoma mansoni rotamase 0.0031 0.0012 0.003
Brugia malayi Receptor family ligand binding region containing protein 0.0168 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0069 0.004 0.0046
Brugia malayi Glutamate receptor 2 precursor 0.0477 0.0344 0.0344
Brugia malayi Dopamine receptor 0.0756 0.0552 0.0552
Mycobacterium ulcerans DNA gyrase subunit B 0.0046 0.0022 0.0508
Echinococcus multilocularis transient receptor potential gamma protein 0.0028 0.0009 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 1.0414 0.7748 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0023 0.0026
Echinococcus multilocularis conserved hypothetical protein 0.0028 0.0009 0.0012
Schistosoma mansoni chromobox protein 0.0068 0.0039 0.0102
Trichomonas vaginalis adenylate cyclase type, putative 0.0034 0.0013 0.026
Onchocerca volvulus 0.0756 0.0552 0.1574
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0009 0.0012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0117 0.0076 0.0097
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.002 0.0003 0.0004
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0093 0.0058 0.0058
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0031 0.0011 0.0313
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0083 0.0107
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0061 0.0034 0.0941
Echinococcus multilocularis nAChR subunit 0.0093 0.0058 0.0074
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Trichomonas vaginalis mercuric reductase, putative 0.0061 0.0034 0.0664
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0011
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0493 0.0355 0.0458
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0756 0.0552 0.0712
Toxoplasma gondii kringle domain-containing protein 0.0038 0.0017 0.0457
Onchocerca volvulus 0.0756 0.0552 0.1574
Onchocerca volvulus 0.0019 0.0003 0.0006
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0077 0.0045 0.0058
Echinococcus multilocularis serotonin receptor 0.3107 0.2304 0.2973
Mycobacterium ulcerans ion transport protein 0.0069 0.004 0.0921
Schistosoma mansoni transient receptor potential channel 0.0028 0.0009 0.0024
Echinococcus granulosus glutamate NMDA receptor subunit 0.1551 0.1144 0.1476
Schistosoma mansoni hypothetical protein 0.0034 0.0013 0.0034
Echinococcus multilocularis glutamate receptor NMDA 0.0652 0.0474 0.0612
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0002 0.0005
Schistosoma mansoni ankyrin 23/unc44 0.002 0.0003 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Trypanosoma cruzi C-8 sterol isomerase, putative 1.161 0.8639 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0042 0.0821
Echinococcus multilocularis somatostatin receptor 0.0756 0.0552 0.0712
Onchocerca volvulus 0.0168 0.0113 0.0323
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1464 0.1079 0.1079
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0026 0.0007 0.0009
Schistosoma mansoni inositol monophosphatase 0.0036 0.0015 0.0038
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0028 0.0009 0.0012
Echinococcus multilocularis neuropeptides capa receptor 0.0756 0.0552 0.0712
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.009 0.0055 0.0064
Mycobacterium ulcerans DNA gyrase subunit A 0.0087 0.0053 0.1221
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0002 0.0005
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0013 0.0249
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0061 0.0034 0.0778
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0026 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0915 0.067 0.0865
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0013 0.0035
Echinococcus granulosus serotonin receptor 0.0756 0.0552 0.0712
Trypanosoma cruzi protein kinase A regulatory subunit 0.0048 0.0024 0.0028
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0013 0.0013
Echinococcus granulosus Mastin 0.0028 0.0009 0.0012
Echinococcus multilocularis expressed conserved protein 0.0101 0.0063 0.0081
Onchocerca volvulus 0.0756 0.0552 0.1574
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0007 0.013
Brugia malayi sulfakinin receptor protein 0.0756 0.0552 0.0552
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0019 0.0374
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0004 0.0005
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0043 0.002 0.0023
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0028 0.0009 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0055 0.1092
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0015 0.1293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0482
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus multilocularis short transient receptor potential channel 6 0.0029 0.001 0.0012
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0013 0.0287
Echinococcus granulosus g-protein coupled receptor 0.0756 0.0552 0.0712
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0028 0.0009 0.0024
Leishmania major cyclic nucleotide-binding protein-like protein 0.0048 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0004 0.0004
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Schistosoma mansoni neurotransmitter gated ion channel 0.005 0.0026 0.0066
Brugia malayi Cation transporter family protein 0.0093 0.0058 0.0058
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0093 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 1.161 0.8639 1
Onchocerca volvulus 0.0043 0.002 0.0057
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0048 0.0024 0.0031
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0093 0.0058 0.0058
Trypanosoma brucei importin beta-1 subunit, putative 0.0042 0.002 0.0023
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0093 0.0058 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0061 0.0034 0.0039
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0087 0.0053 0.1477
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0038 0.0753
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0037 0.0016 0.0018
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0001 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Brugia malayi Kringle domain containing protein 0.0038 0.0017 0.0017
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0037 0.0016 0.0019
Mycobacterium tuberculosis Probable oxidoreductase 0.0447 0.0321 0.7468
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0017 0.0001 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Schistosoma mansoni biogenic amine receptor 0.0756 0.0552 0.1442
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0015 0.034
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0048 0.0024 0.0673
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0004 0.0004
Echinococcus multilocularis nAChR subunit 0.005 0.0026 0.0033
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0593 0.043 0.3983
Brugia malayi cation channel family protein 0.0028 0.0009 0.0009
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Plasmodium vivax DNA gyrase subunit A, putative 0.0087 0.0053 0.1477
Schistosoma mansoni intermediate filament proteins 0.0026 0.0008 0.002
Echinococcus granulosus glutamate receptor subunit protein glur 0.0322 0.0228 0.0294
Loa Loa (eye worm) voltage-gated potassium channel 0.0028 0.0009 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0007 0.0008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0756 0.0552 0.1442
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0048 0.0024 0.0031
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0285 0.0201 0.0232
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0011 0.0012
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0048 0.0024 0.0028
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0006 0.0006
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0097 0.006 0.007
Loa Loa (eye worm) RNA binding protein 0.0128 0.0083 0.0096
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0061 0.0034 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0002 0.0002
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0027 0.0009 0.0191
Treponema pallidum NADH oxidase 0.0061 0.0034 0.031
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0021 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0756 0.0552 0.1442
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0004 0.0654
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Schistosoma mansoni acetylcholine receptor subunit beta 0.0043 0.002 0.0052
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0645 0.0469 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0055 0.1092
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0121 0.0078 0.0204
Plasmodium falciparum thioredoxin reductase 0.0061 0.0034 0.0941
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0006 0.0123
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0039 0.0773
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0037 0.0016 0.0353
Loa Loa (eye worm) TOPoisomerase family member 0.0025 0.0007 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Plasmodium falciparum cysteine repeat modular protein 1 0.0038 0.0017 0.0457
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0048 0.0024 0.0031
Schistosoma mansoni neurotransmitter gated ion channel 0.0043 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0168 0.0113 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0228
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0093 0.0058 0.015
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0004 0.0111
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0037 0.0016 0.0353
Mycobacterium ulcerans hypothetical protein 0.0048 0.0024 0.0556
Trichomonas vaginalis rotamase, putative 0.0031 0.0012 0.0228
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0027 0.0009 0.001
Echinococcus multilocularis glycoprotein Antigen 5 0.0028 0.0009 0.0012
Echinococcus multilocularis potassium voltage gated channel protein 0.0028 0.0009 0.0012
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0011 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0024 0.0062
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0023 0.0029
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0013 0.0035
Leishmania major importin beta-1 subunit, putative 0.0034 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Schistosoma mansoni vesicular amine transporter 0.0033 0.0013 0.0032
Trypanosoma brucei protein kinase A regulatory subunit 0.0048 0.0024 0.0028
Brugia malayi steroid hormone receptor 0.0019 0.0002 0.0002
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0093 0.0058 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0483
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0037 0.0016 0.0353
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0002 0.0002
Echinococcus multilocularis glutamate receptor 2 0.0477 0.0344 0.0444
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0059 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi Death domain containing protein 0.002 0.0003 0.0003
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0037 0.0016 0.0353
Onchocerca volvulus 0.0093 0.0058 0.0163
Brugia malayi AKH receptor 0.0756 0.0552 0.0552
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.0756 0.0552 0.0712
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0 0.0005
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0028 0.0009 0.0012
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0061 0.0034 0.0941
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Leishmania major cytochrome p450-like protein 0.0074 0.0043 0.005
Schistosoma mansoni polycystin 1-related 0.0019 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0087 0.0053 0.0486
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0028
Schistosoma mansoni glutamate receptor kainate 0.0477 0.0344 0.0899
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0168 0.0113 0.0131
Brugia malayi glutathione reductase 0.0176 0.012 0.012
Trichomonas vaginalis DNA topoisomerase II, putative 0.0025 0.0007 0.0138
Loa Loa (eye worm) calcium channel 0.0028 0.0009 0.001
Toxoplasma gondii DNA topoisomerase 2, putative 0.0025 0.0007 0.0189
Plasmodium falciparum glutathione reductase 0.0061 0.0034 0.0941
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0023 0.0026
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0006 0.0123
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni survival motor neuron protein 0.0047 0.0024 0.0061
Trypanosoma cruzi cAMP response protein 1, putative 0.0048 0.0024 0.0028
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0083 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0002 0.0002
Trypanosoma brucei C-8 sterol isomerase, putative 1.161 0.8639 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0841 0.0615 0.0793
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Brugia malayi UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 0.0027 0.0008 0.0008
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0087 0.0053 0.1221
Trichomonas vaginalis hypothetical protein 0.0034 0.0013 0.026
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus multilocularis G protein coupled receptor 139 0.0756 0.0552 0.0712
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0037 0.0016 0.0018
Brugia malayi Trypsin family protein 0.0282 0.0198 0.0198
Entamoeba histolytica Ran family GTPase 0.0031 0.0011 0.0983
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0048 0.0024 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.024 0.0167 0.3289
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0006 0.0467
Brugia malayi hypothetical protein 0.0493 0.0355 0.0355
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Echinococcus multilocularis neuropeptide s receptor 0.095 0.0696 0.0898
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0121 0.0078 0.0078
Echinococcus granulosus chromobox protein 1 0.0068 0.0039 0.005
Plasmodium vivax importin-beta 2, putative 0.0042 0.002 0.0547
Schistosoma mansoni lamin 0.0026 0.0008 0.002
Echinococcus multilocularis protein dispatched 1 0.0052 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0001 0.0013
Schistosoma mansoni neuropeptide receptor 0.0756 0.0552 0.1442
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0285 0.0201 0.0232
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0077 0.0045 0.0052
Echinococcus granulosus cGMP dependent protein kinase 0.0048 0.0024 0.0031
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0109 0.0069 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0032 0.0627
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0493 0.0355 0.0929
Echinococcus multilocularis glycine receptor subunit beta 0.0093 0.0058 0.0074
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0029 0.001 0.0011
Loa Loa (eye worm) UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 0.0027 0.0008 0.0009
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0037 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0282 0.0198 0.0229
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0027 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0037 0.0016 0.0353
Echinococcus granulosus biogenic amine 5HT receptor 0.3107 0.2304 0.2973
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0006 0.0123
Mycobacterium ulcerans beta-lactamase 0.0027 0.0009 0.0191
Loa Loa (eye worm) G-protein coupled receptor 0.0756 0.0552 0.0638
Echinococcus multilocularis pyruvate kinase 0.0033 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Brugia malayi RNA, U transporter 1 0.012 0.0078 0.0078
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0168 0.0113 0.0146
Trypanosoma brucei trypanothione reductase 0.0176 0.012 0.0138
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0025 0.0007 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0037 0.0016 0.0353
Brugia malayi Trypsin family protein 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.005 0.0026 0.0029
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0756 0.0552 0.0712
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0028 0.0009 0.0024
Echinococcus granulosus tm gpcr rhodopsin 1.0414 0.7748 1
Echinococcus multilocularis tyrosine kinase 0.0168 0.0113 0.0146
Loa Loa (eye worm) hypothetical protein 0.0493 0.0355 0.0411
Loa Loa (eye worm) G-protein coupled receptor 0.0756 0.0552 0.0638
Loa Loa (eye worm) glutamate receptor 2 0.0477 0.0344 0.0398
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0168 0.0113 0.0113
Trypanosoma cruzi trypanothione reductase, putative 0.0176 0.012 0.0138
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0001 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0447 0.0321 1
Echinococcus multilocularis RUN 0.0019 0.0003 0.0003
Echinococcus multilocularis fmrfamide receptor 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Echinococcus granulosus neutral alpha glucosidase AB 0.0026 0.0007 0.0009
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0048 0.0024 0.0024
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0017 0.0331
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0013 0.0015
Onchocerca volvulus 0.0756 0.0552 0.1574
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0037 0.0016 0.0353
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0055
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0028 0.0009 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0042 0.0821
Loa Loa (eye worm) MH2 domain-containing protein 0.0306 0.0216 0.025
Mycobacterium tuberculosis Conserved protein 0.0027 0.0009 0.0191
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0048 0.0024 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0037 0.0016 0.0353
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0029 0.001 0.0025
Schistosoma mansoni voltage-gated ion channel 0.0028 0.0009 0.0024
Onchocerca volvulus Neuropeptide F receptor homolog 0.0756 0.0552 0.1574
Onchocerca volvulus 0.0028 0.0009 0.0026
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0002 0.0002
Echinococcus granulosus expressed conserved protein 0.0101 0.0063 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0011 0.0212
Brugia malayi Metabotropic glutamate receptor precursor. 0.0168 0.0113 0.0113
Echinococcus multilocularis glutamate receptor 2 0.0323 0.0229 0.0295
Brugia malayi hypothetical protein 0.0043 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0048 0.0024 0.0062
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0048 0.0024 0.0062
Echinococcus multilocularis neuropeptides capa receptor 0.0756 0.0552 0.0712
Brugia malayi Transient-receptor-potential like protein 0.0028 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Brugia malayi Serotonin receptor 0.0756 0.0552 0.0552
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0048 0.0024 0.0556
Echinococcus granulosus enteropeptidase 0.0028 0.0009 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0015 0.0018
Schistosoma mansoni sodium-dependent amino acid transporter 0.0493 0.0355 0.0929
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0028
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Echinococcus multilocularis musashi 0.0026 0.0008 0.001
Echinococcus granulosus glycine receptor subunit beta 0.0093 0.0058 0.0074
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0061 0.0034 0.0778
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Schistosoma mansoni bromodomain containing protein 0.0068 0.0039 0.0101
Echinococcus granulosus potassium voltage gated channel subfamily H 0.011 0.007 0.009
Loa Loa (eye worm) ion channel NompC 0.0028 0.0009 0.001
Loa Loa (eye worm) RecQ helicase 0.0021 0.0004 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0007 0.013
Echinococcus granulosus glutamate receptor NMDA 0.0652 0.0474 0.0612
Brugia malayi Tachykinin-like peptides receptor 99D 0.0756 0.0552 0.0552
Schistosoma mansoni adenoreceptor 0.0756 0.0552 0.1442
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0077 0.0045 0.0052
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Brugia malayi Melatonin receptor type 1A 0.0756 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0002 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0756 0.0552 0.1442
Toxoplasma gondii hypothetical protein 0.0028 0.0009 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0002 0.0002
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0001 0.0004
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.026
Trichomonas vaginalis importin beta-1, putative 0.0034 0.0014 0.0271
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0028 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.269 0.1992 0.5211
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0002 0.0002
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.009 0.0055 0.0064
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0045 0.0022 0.0022
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0007 0.0144
Toxoplasma gondii thioredoxin reductase 0.0176 0.012 0.3358
Echinococcus multilocularis biogenic amine (5HT) receptor 0.5146 0.3823 0.4934
Echinococcus granulosus metabotropic glutamate receptor 5 0.0168 0.0113 0.0146
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0012 0.0368
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0161 0.0208
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.001 0.001
Loa Loa (eye worm) glutathione reductase 0.0176 0.012 0.0138
Echinococcus granulosus rhodopsin orphan GPCR 0.0756 0.0552 0.0712
Schistosoma mansoni hypothetical protein 0.0047 0.0024 0.0061
Loa Loa (eye worm) hypothetical protein 0.0067 0.0038 0.0044
Onchocerca volvulus 0.0493 0.0355 0.1013
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0493 0.0355 0.0411
Loa Loa (eye worm) acetyltransferase 0.0105 0.0067 0.0077
Onchocerca volvulus 0.0043 0.002 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0007 0.0144
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.002 0.0025
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0756 0.0552 0.0712
Mycobacterium tuberculosis Probable hydrolase 0.0027 0.0009 0.0191
Plasmodium vivax glutathione reductase, putative 0.0176 0.012 0.3358
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0007 0.013
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0061 0.0034 0.0941
Loa Loa (eye worm) hypothetical protein 0.0093 0.0058 0.0066
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0016 0 0.0005
Onchocerca volvulus 0.0756 0.0552 0.1574
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0612 0.0444 0.0514
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0048 0.0024 0.0062
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0028 0.0009 0.0012
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0028 0.0009 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0483
Echinococcus multilocularis G-protein coupled receptor, putative 0.0756 0.0552 0.0712
Brugia malayi MH1 domain containing protein 0.0021 0.0004 0.0004
Leishmania major cytochrome p450-like protein 0.0037 0.0016 0.0018
Schistosoma mansoni chromobox protein 0.0068 0.0039 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0007 0.0008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.009 0.0055 0.0064
Schistosoma mansoni eyes absent homolog 0.0067 0.0038 0.0098
Schistosoma mansoni neuropeptide receptor 0.0756 0.0552 0.1442
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0117 0.0076 0.0076
Echinococcus granulosus sodium leak channel non selective protein 0.0028 0.0009 0.0012
Trypanosoma cruzi target of rapamycin kinase 3 0.0072 0.0042 0.0048
Chlamydia trachomatis glutamine binding protein 0.0593 0.043 1
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0043 0.002 0.002
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0093 0.0058 0.0058
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0034 0.0013 0.026
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0034 0.0013 0.026
Brugia malayi intermediate filament protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) TYRA-2 protein 0.0756 0.0552 0.0638
Schistosoma mansoni glutamate receptor NMDA 0.1551 0.1144 0.2992
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Echinococcus granulosus lysosomal alpha glucosidase 0.0116 0.0074 0.0096
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0093 0.0058 0.0074
Onchocerca volvulus 0.0093 0.0058 0.0163
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Leishmania major pyruvate kinase 0.0033 0.0013 0.0015
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0007 0.0144
Echinococcus granulosus dnaJ subfamily B 0.0665 0.0484 0.0624
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0061 0.0034 0.0941
Mycobacterium leprae Possible transporter protein 0.0034 0.0013 0.0403
Schistosoma mansoni neuropeptide F-like receptor 0.0756 0.0552 0.1442
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0001 0.0013
Loa Loa (eye worm) thioredoxin reductase 0.0176 0.012 0.0138
Schistosoma mansoni hypothetical protein 0.0373 0.0266 0.0695
Onchocerca volvulus 0.005 0.0026 0.0072
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Schistosoma mansoni rab6-interacting 0.0019 0.0003 0.0006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0017 0.0047
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0043 0.002 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0002 0.0002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0756 0.0552 0.0638
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0061 0.0034 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0002 0.0002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0011 0.0212
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0025 0.0007 0.0008
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0048 0.0024 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0157 0.0105 0.2078
Brugia malayi Guanylyl cyclase protein 23 0.0168 0.0113 0.0113
Echinococcus granulosus nAChR subunit 0.0093 0.0058 0.0074
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0012 0.0275
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0028 0.0009 0.0024
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0048 0.0024 0.0062
Trichomonas vaginalis adenylate cyclase type, putative 0.0034 0.0013 0.026
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0055
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0084 0.0051 0.0066
Brugia malayi Bromodomain containing protein 0.004 0.0018 0.0018
Brugia malayi Pre-SET motif family protein 0.0612 0.0444 0.0444
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0756 0.0552 0.0638
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0093 0.0058 0.0058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0756 0.0552 0.0712
Echinococcus granulosus glycine receptor subunit alpha 1 0.0093 0.0058 0.0074
Schistosoma mansoni egf-like domain protein 0.0029 0.001 0.0025
Brugia malayi Glutamate receptor 1 precursor 0.0477 0.0344 0.0344
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Echinococcus multilocularis Tolloid protein 1 0.0029 0.001 0.0012
Toxoplasma gondii cytochrome p450 superfamily protein 0.0037 0.0016 0.0427
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0093 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Schistosoma mansoni hypothetical protein 0.0028 0.0009 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0037 0.0016 0.0353
Brugia malayi isocitrate dehydrogenase 0.0026 0.0007 0.0007
Echinococcus granulosus tachykinin peptides receptor 99D 0.0756 0.0552 0.0712
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0001
Brugia malayi hypothetical protein 0.0028 0.0009 0.0009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0001 0.0024
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.011 0.007 0.009
Schistosoma mansoni smad1 5 8 and 0.0021 0.0004 0.0009
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0093 0.0058 0.0074
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0093 0.0058 0.0058
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0005 0.0006
Onchocerca volvulus Netrin receptor homolog 0.002 0.0003 0.0008
Schistosoma mansoni growth hormone secretagogue receptor 0.0756 0.0552 0.1442
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0493 0.0355 0.8264
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0061 0.0034 0.0039
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0176 0.012 0.2775
Onchocerca volvulus 0.0019 0.0003 0.0006
Schistosoma mansoni nAChR subunit 0.0093 0.0058 0.015
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0593 0.043 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0168 0.0113 0.0323
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0046 0.0118
Onchocerca volvulus 0.0028 0.0009 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0042 0.0821
Loa Loa (eye worm) hypothetical protein 0.0056 0.003 0.0035
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0013 0.0035
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0028 0.0009 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0034 0.0013 0.026
Echinococcus granulosus O glycosyltransferase 0.0027 0.0008 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0002 0.0002
Schistosoma mansoni two-pore calcium channel 0.0028 0.0009 0.0024
Echinococcus granulosus cpg binding protein 0.0065 0.0037 0.0047
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.171 0.1262 0.1461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0483
Echinococcus multilocularis lysosomal alpha glucosidase 0.0116 0.0074 0.0096
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0106 0.0067 0.0086
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0004 0.0083
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0028 0.0009 0.0012
Trichomonas vaginalis glutathione reductase, putative 0.0061 0.0034 0.0664
Onchocerca volvulus 0.0756 0.0552 0.1574
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0028 0.0009 0.0009
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0043 0.002 0.002
Onchocerca volvulus 0.0027 0.0009 0.0023
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0037 0.0016 0.0353
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0038 0.0017 0.0457
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0009 0.0254
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0006 0.0123
Brugia malayi G-protein coupled receptor 0.0756 0.0552 0.0552
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0093 0.0058 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0756 0.0552 0.1442
Onchocerca volvulus 0.0059 0.0033 0.0092
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0026 0.0007 0.0009
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0013 0.0348
Onchocerca volvulus 0.0756 0.0552 0.1574
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0023
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0037 0.0016 0.0353
Echinococcus granulosus voltage dependent calcium channel 0.0028 0.0009 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0009 0.0024
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0107 0.0068 0.5992
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0093 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.001
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0003 0.0061
Echinococcus granulosus transient receptor potential gamma protein 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.3107 0.2304 0.2666
Echinococcus multilocularis Ankyrin 0.002 0.0003 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0493 0.0355 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0034 0.556
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0034 0.0013 0.026
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.005 0.0026 0.0026
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0093 0.0058 0.0074
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0028 0.0009 0.0009
Leishmania major protein kinase, putative 0.0048 0.0024 0.0028
Echinococcus granulosus voltage gated potassium channel 0.011 0.007 0.009
Trichomonas vaginalis adenylate cyclase, putative 0.0034 0.0013 0.026
Schistosoma mansoni smad1 5 8 and 0.0021 0.0004 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0009 0.0167
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0037 0.0016 0.0018
Onchocerca volvulus Glucosylceramidase homolog 0.0157 0.0105 0.03
Schistosoma mansoni calcium-activated potassium channel 0.0028 0.0009 0.0024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0034 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.002 0.0025
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.4718 0.3504 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0027 0.0009 0.0191
Echinococcus granulosus glutamate receptor 2 0.0645 0.0469 0.0605
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0023 0.0029
Schistosoma mansoni nAChR subunit 0.0043 0.002 0.0052
Echinococcus granulosus g protein coupled receptor 0.0756 0.0552 0.0712
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis transient receptor potential cation channel 0.0028 0.0009 0.0012
Mycobacterium ulcerans hypothetical protein 0.0048 0.0024 0.0556
Echinococcus granulosus TRP transient receptor potential channel 0.0028 0.0009 0.0012
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0034 0.0013 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0006 0.0123
Onchocerca volvulus 0.0282 0.0198 0.0564
Echinococcus multilocularis shaker cognate 0.0028 0.0009 0.0012
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0025 0.0007 0.0007
Echinococcus granulosus patatin phospholipase domain containing protein 0.0048 0.0024 0.0031
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0033 0.0037
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0024 0.0024
Echinococcus multilocularis chromobox protein 1 0.0068 0.0039 0.005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0004 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.011 0.007 0.0183
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0003 0.0061
Echinococcus granulosus glutamate receptor 2 0.0323 0.0229 0.0295
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0002 0.0002
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0026 0.0007 0.0009
Echinococcus multilocularis geminin 0.0373 0.0266 0.0343
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0121 0.0078 0.01
Loa Loa (eye worm) hypothetical protein 0.171 0.1262 0.1461
Schistosoma mansoni glutamate receptor NMDA 0.1298 0.0955 0.2498
Echinococcus granulosus tyrosine kinase 0.0168 0.0113 0.0146
Schistosoma mansoni hypothetical protein 0.0028 0.0009 0.0024
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0043 0.002 0.0026
Trichomonas vaginalis esterase, putative 0.0027 0.0009 0.0167
Brugia malayi Cytochrome P450 family protein 0.0037 0.0016 0.0016
Giardia lamblia Pyruvate kinase 0.0017 0.0001 0.0076
Echinococcus granulosus Smad4 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0756 0.0552 0.0638
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0026 0.0007 0.0009
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0756 0.0552 0.0712
Loa Loa (eye worm) ACC-1 protein 0.0093 0.0058 0.0066
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0072 0.0042 0.0048
Echinococcus multilocularis expressed conserved protein 0.0048 0.0024 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0028 0.0559
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0093 0.0058 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0028 0.0551
Onchocerca volvulus 0.0756 0.0552 0.1574
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0031 0.0011 0.0013
Echinococcus granulosus mothers against decapentaplegic 5 0.0021 0.0004 0.0004
Trichomonas vaginalis glutamate synthase, putative 0.0016 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0402 0.0288 0.669
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0009 0.0024
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.009 0.0055 0.0144
Echinococcus multilocularis sodium and chloride dependent glycine 0.171 0.1262 0.1629
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0083 0.0217
Echinococcus multilocularis transfer RNA-Gly 0.0028 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.002 0.002
Echinococcus multilocularis sodium and chloride dependent glycine 0.171 0.1262 0.1629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0025 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.0166
Schistosoma mansoni amine GPCR 0.0756 0.0552 0.1442
Mycobacterium ulcerans transmembrane transport protein 0.0053 0.0027 0.0631
Schistosoma mansoni ap endonuclease 0.0021 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.001
Loa Loa (eye worm) Smad1 0.0021 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0038 0.0017 0.0019
Schistosoma mansoni transient receptor potential channel 0.0029 0.001 0.0024
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0077 0.0045 0.0058
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0493 0.0355 0.0355
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0016 0 0.0005
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0028 0.0009 0.0012
Onchocerca volvulus 0.0028 0.0009 0.0026
Plasmodium falciparum transporter, putative 0.0493 0.0355 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0002 0.0002

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 0 % GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. ChEMBL. 20485427
Inhibition (functional) = 5 % GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM ChEMBL. 20485427
Inhibition (functional) = 76 % GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM ChEMBL. 20485427
Inhibition (functional) = 98 % GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM ChEMBL. 20485427
Inhibition frequency index (IFI) (functional) = 22.5 Inhibition Frequency Index (IFI) GSK. 20485427
Percent growth inhibition (functional) = -4 % Percent inhibition of HepG2 growth (at 10 uM) GSK. 20485427
Percent growth inhibition (functional) = 5 % Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) GSK. 20485427
Percent growth inhibition (functional) = 76 % Percent inhibition of P. falciparum Dd2 growth (at 2 uM) GSK. 20485427
Percent growth inhibition (functional) = 98 % Percent inhibition of P. falciparum 3D7 growth (at 2 uM) GSK. 20485427
XC50 (functional) = 6.07 XC50 determination of P. falciparum 3D7 growth GSK. 20485427
XC50 (functional) = 0.84904 uM GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. ChEMBL. 20485427

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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