Detailed information for compound 1381635

Basic information

Technical information
  • TDR Targets ID: 1381635
  • Name: 1,3-dimethyl-5-[(5-piperidin-1-ylfuran-2-yl)m ethylidene]-2-sulfanylidene-1,3-diazinane-4,6 -dione
  • MW: 333.405 | Formula: C16H19N3O3S
  • H donors: 0 H acceptors: 2 LogP: 2.33 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1C(=S)N(C)C(=O)C(=Cc2ccc(o2)N2CCCCC2)C1=O
  • InChi: 1S/C16H19N3O3S/c1-17-14(20)12(15(21)18(2)16(17)23)10-11-6-7-13(22-11)19-8-4-3-5-9-19/h6-7,10H,3-5,8-9H2,1-2H3
  • InChiKey: BXCQFCMBKWXNSL-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 1,3-dimethyl-5-[[5-(1-piperidyl)-2-furyl]methylene]-2-thioxo-hexahydropyrimidine-4,6-dione
  • 1,3-dimethyl-5-[[5-(1-piperidyl)-2-furyl]methylene]-2-thioxohexahydropyrimidine-4,6-dione
  • 1,3-dimethyl-5-[(5-piperidino-2-furyl)methylene]-2-thioxo-hexahydropyrimidine-4,6-quinone
  • STK187173
  • SMR000141413
  • 1,3-dimethyl-5-{[5-(1-piperidinyl)-2-furyl]methylene}-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
  • ZINC00450826
  • MLS000533977

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus glycogen phosphorylase 0.0219 0.016 0.0159
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0008 0.0007
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0026 0.0025
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0017 0.0008 0.0007
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0017 0.0371
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0012 0.0004 0.0082
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0005 0.0097
Loa Loa (eye worm) hypothetical protein 0.018 0.0131 0.013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0028 0.0034
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0004 0.0071
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0052 0.1197
Echinococcus granulosus allatostatin A receptor 0.0025 0.0014 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0036 0.0036
Echinococcus granulosus TRP transient receptor potential channel 0.0017 0.0008 0.0007
Plasmodium falciparum subtilisin-like protease 2 0.0576 0.0429 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Echinococcus granulosus neuropeptide FF receptor 2 0.0025 0.0014 0.0013
Brugia malayi Cytochrome P450 family protein 0.0029 0.0017 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0022 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0016 0.0007 0.0142
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0008 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0183 0.0133 0.0164
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0005 0.0005
Toxoplasma gondii subtilisin SUB7 0.0576 0.0429 1
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.001 0.0216
Loa Loa (eye worm) voltage-dependent calcium channel 0.0113 0.0081 0.008
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0004 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0014 0.0013
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0008 0.0002 0.0014
Echinococcus multilocularis shaker cognate 0.0018 0.0009 0.0009
Brugia malayi jmjC domain containing protein 0.0032 0.0019 0.0018
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0004 0.0082
Loa Loa (eye worm) steroid hormone receptor 0.0183 0.0133 0.0132
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.0151 0.015
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0007 0.0381
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0183 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0009 0.0009
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0016 0.0007 0.0142
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0001 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0001 0.0007
Echinococcus multilocularis chromobox protein 2 0.0011 0.0004 0.0003
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Echinococcus granulosus intermediate filament protein 0.0027 0.0015 0.0014
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0025 0.0558
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0011 0.0013
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0576 0.0429 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0005 0.0004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0018 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0007 0.001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0002 0.0008
Trypanosoma brucei trypanothione reductase 0.0049 0.0032 0.0731
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0005 0.0097
Trichomonas vaginalis hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0319 0.0235 0.0235
Schistosoma mansoni smad 0.001 0.0003 0.0003
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0008 0.0001 0.0007
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0017 0.0008 0.0007
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0008 0.0166
Toxoplasma gondii thioredoxin reductase 0.0049 0.0032 0.0738
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0183 0.0133 0.0132
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0196 0.0143 0.0177
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0009 0.0007
Leishmania major cytochrome p450-like protein 0.002 0.0011 0.0218
Echinococcus multilocularis chromobox protein 1 0.0011 0.0004 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.0183 0.0133 0.0164
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0008 0.0002 0.0023
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0008 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni transient receptor potential channel 0.0017 0.0008 0.0008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0033 0.0032
Echinococcus granulosus g-protein coupled receptor 0.0025 0.0014 0.0013
Trichomonas vaginalis rotamase, putative 0.004 0.0026 0.004
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0319 0.0235 0.0291
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0017
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0086 0.006 0.1392
Leishmania major hypothetical protein, conserved 0.003 0.0018 0.0401
Mycobacterium ulcerans monophosphatase 0.0012 0.0004 0.0076
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0017 0.0008 0.0156
Mycobacterium leprae putative cytochrome p450 0.002 0.0011 0.0218
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Entamoeba histolytica glycogen phosphorylase, putative 0.0219 0.016 1
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0069 0.0048 0.109
Brugia malayi jmjC domain containing protein 0.0032 0.0019 0.0018
Mycobacterium ulcerans epimerase 0.002 0.001 0.0216
Onchocerca volvulus 0.0027 0.0015 0.0341
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0022 0.0491
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0017 0.0369
Mycobacterium tuberculosis Probable exported protein 0.0008 0.0002 0.0015
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0011 0.0011
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0062 0.0042 0.0042
Onchocerca volvulus 0.0025 0.0014 0.0307
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0019 0.0018
Onchocerca volvulus 0.0049 0.0032 0.0732
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0004 0.0071
Brugia malayi Pre-SET motif family protein 0.003 0.0018 0.0017
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0008 0.0001 0.0007
Trypanosoma cruzi hypothetical protein 0.0012 0.0005 0.0078
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0031 0.003
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0183 0.0133 0.0132
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0014 0.0014
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0039 0.0025 0.0023
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0008 0.0008
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0086 0.006 0.0059
Schistosoma mansoni carbon catabolite repressor protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0095 0.0067 0.1532
Toxoplasma gondii subtilisin SUB6 0.0576 0.0429 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.005 0.0061
Plasmodium falciparum thioredoxin reductase 0.0017 0.0008 0.0173
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0319 0.0235 0.0234
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus ecdysone induced protein 78C 0.0183 0.0133 0.0132
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0017 0.0369
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0017 0.0993
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0016 0.0007 0.0142
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0026 0.004
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0025 0.0025
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0001 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0036 0.0036
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0008 0.0002 0.0016
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0086 0.006 0.0074
Brugia malayi voltage-dependent calcium channel 0.0017 0.0008 0.0007
Schistosoma mansoni alkaline phosphatase 0.0196 0.0143 0.0143
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0018 0.0017
Onchocerca volvulus 0.0025 0.0014 0.0307
Brugia malayi nuclear hormone receptor 0.0086 0.006 0.006
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0021 0.0033
Echinococcus granulosus sodium channel protein 0.0017 0.0008 0.0007
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0002 0.0021
Loa Loa (eye worm) calcium channel 0.0319 0.0235 0.0234
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0026 0.0572
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0008 0.0001 0.0007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0028 0.063
Brugia malayi Protein arginine N-methyltransferase 0.0038 0.0024 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0086 0.006 0.1392
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0081 0.0057 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0005 0.0004
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0016 0.0007 0.0142
Trypanosoma brucei polo-like protein kinase 0.0114 0.0082 0.1877
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0015 0.0325
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.001 0.0223
Echinococcus granulosus fmrfamide receptor 0.0025 0.0014 0.0013
Echinococcus granulosus chromobox protein 1 0.0011 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Brugia malayi Heterochromatin protein 1 0.0011 0.0004 0.0003
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0318
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0008 0.0164
Brugia malayi Transient-receptor-potential like protein 0.0017 0.0008 0.0007
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0017 0.0008 0.0007
Echinococcus granulosus intestinal type alkaline phosphatase 0.0196 0.0143 0.0142
Echinococcus multilocularis ecdysone induced protein 78C 0.0183 0.0133 0.0164
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0025 0.0014 0.0014
Schistosoma mansoni cpg binding protein 0.0037 0.0023 0.0023
Schistosoma mansoni biogenic amine receptor 0.0025 0.0014 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0017 0.0369
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0004 0.0004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0114 0.0081 0.1879
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0183 0.0133 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.001 0.0014
Echinococcus granulosus furin 1.3293 1 1
Echinococcus granulosus neuropeptide receptor A26 0.0984 0.0736 0.0735
Plasmodium falciparum subtilisin-like protease 1 0.0576 0.0429 1
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0034 0.0033
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0018 0.0401
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0004 0.0003
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0003 0.0003
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Echinococcus multilocularis GPCR, family 2 0.005 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0576 0.0429 1
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0008 0.0007
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0008 0.0002 0.0001
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0086 0.006 0.006
Brugia malayi jmjC domain containing protein 0.0119 0.0085 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0009 0.0009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0025 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Toxoplasma gondii carbonyl reductase 1, putative 0.0008 0.0001 0.0007
Schistosoma mansoni hypothetical protein 0.0353 0.0261 0.0261
Schistosoma mansoni nuclear receptor 0.0086 0.006 0.006
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.0082 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0007 0.001
Echinococcus multilocularis Ankyrin 0.0014 0.0006 0.0006
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0576 0.0429 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3185 0.2392 0.3925
Onchocerca volvulus 0.0012 0.0004 0.0082
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0008 0.0002 0.0014
Schistosoma mansoni hypothetical protein 0.005 0.0033 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0019 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0014 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.009 0.009
Echinococcus multilocularis protein patched 0.0051 0.0034 0.0041
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0017 0.2719
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.0984 0.0736 0.0914
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Onchocerca volvulus 0.0008 0.0002 0.0016
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0019 0.0423
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0008 0.0002 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0002 0.0021
Onchocerca volvulus Protein ultraspiracle homolog 0.0183 0.0133 0.3093
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0183 0.0133 0.0132
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0026 0.0579
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0031 0.0031
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0011 0.0011
Leishmania major hypothetical protein, conserved 0.0017 0.0008 0.0156
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0012 0.0004 0.0075
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0025 0.0014 0.0016
Onchocerca volvulus 0.0035 0.0022 0.0483
Echinococcus granulosus flap endonuclease 1 0.0026 0.0015 0.0014
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0006 0.0006
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0004 0.0003
Mycobacterium ulcerans lipase LipD 0.0043 0.0028 0.063
Brugia malayi neuroendocrine convertase 1 precursor 0.8376 0.6299 0.6299
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0009 0.0009
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0009 0.0002 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0028 0.0637
Mycobacterium ulcerans hypothetical protein 0.002 0.001 0.0216
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0025 0.0014 0.0013
Plasmodium falciparum glutathione reductase 0.0017 0.0008 0.0173
Echinococcus granulosus potassium voltage gated channel protein 0.0039 0.0025 0.0023
Brugia malayi chromobox protein homolog 3 0.0011 0.0004 0.0003
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus multilocularis 1.0685 0.8037 1
Echinococcus granulosus sex peptide receptor 0.0025 0.0014 0.0013
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0026 0.004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0183 0.0133 0.0133
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0032 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0011 0.0004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0319 0.0235 0.0234
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0011 0.0225
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0011 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0183 0.0133 0.0132
Echinococcus multilocularis chromobox protein 1 0.0011 0.0004 0.0003
Echinococcus granulosus orexin receptor type 2 0.0025 0.0014 0.0013
Echinococcus granulosus voltage dependent calcium channel 0.0113 0.0081 0.0079
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.0082 0.008
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0046 0.1047
Brugia malayi MH2 domain containing protein 0.001 0.0003 0.0002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0119 0.0085 0.0104
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.0001 0.0001
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0025 0.0558
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0014 0.0016
Echinococcus multilocularis inositol monophosphatase 0.0012 0.0004 0.0004
Schistosoma mansoni netrin receptor unc5 0.0014 0.0006 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.001 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Toxoplasma gondii subtilisin SUB4 0.0576 0.0429 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0051 0.0033 0.0033
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0576 0.0429 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0011 0.0218
Brugia malayi hypothetical protein 0.0286 0.021 0.021
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0004
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0019 0.043
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0017 0.0371
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.01 0.0071 0.007
Onchocerca volvulus 0.0025 0.0014 0.0307
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Toxoplasma gondii ABC1 family protein 0.0043 0.0028 0.0637
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0025 0.0014 0.0013
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0249
Giardia lamblia Furin precursor putative serine protease 0.2609 0.1959 0.5297
Brugia malayi nuclear receptor NHR-88 0.0183 0.0133 0.0132
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0002 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0018 0.0401
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0016 0.0007 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0006
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 0.3351
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0007 0.0381
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0007 0.0016
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0021 0.0011 0.0013
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0038 0.0024 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0014 0.0014
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0038 0.0024 0.0037
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0005 0.0005
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0004 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0014 0.0016
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 0.1303
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0038 0.0061
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0001 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0008 0.0007
Brugia malayi Tachykinin-like peptides receptor 99D 0.0025 0.0014 0.0013
Brugia malayi Flap endonuclease-1 0.0026 0.0015 0.0014
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0008 0.0884
Echinococcus multilocularis nuclear receptor nhr 48 0.0086 0.006 0.0074
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0028 0.0027
Brugia malayi M-phase phosphoprotein, mpp8 0.01 0.0071 0.007
Mycobacterium tuberculosis Conserved protein 0.0043 0.0028 0.0637
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0076 0.0075
Onchocerca volvulus 0.0043 0.0028 0.0637
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0004 0.0004
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0014 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.001 0.0014
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.8103 0.6093 0.6093
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0001 0.0007
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0014 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0028 0.063
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0017 0.0016
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0081 0.0132
Brugia malayi MH1 domain containing protein 0.001 0.0003 0.0002
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0018 0.0009 0.0007
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0576 0.0429 1
Schistosoma mansoni amine GPCR 0.0025 0.0014 0.0014
Brugia malayi MH2 domain containing protein 0.0144 0.0104 0.0103
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0041 0.004
Onchocerca volvulus Huntingtin homolog 0.0129 0.0093 0.2148
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0011 0.0225
Entamoeba histolytica glycogenphosphorylase, putative 0.0095 0.0067 0.4119
Echinococcus granulosus alkaline phosphatase 0.0196 0.0143 0.0142
Schistosoma mansoni histamine h1 receptor 0.0025 0.0014 0.0014
Brugia malayi nuclear receptor NHR-67 0.0086 0.006 0.006
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0576 0.0429 0.0533
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0069 0.0048 0.109
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0008 0.0002 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0002 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0028 0.0637
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0025 0.0014 0.0013
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0004 0.0201
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0015 0.0022
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0028 0.0637
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0004 0.0071
Schistosoma mansoni site-1 peptidase (S08 family) 0.0576 0.0429 0.0429
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0009 0.0009
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0008 0.0001 0.0007
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0052 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.2609 0.1959 0.1959
Schistosoma mansoni protein kinase 0.002 0.001 0.001
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0017 0.0008 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus epidermal growth factor receptor 0.0366 0.0271 0.027
Echinococcus multilocularis G-protein coupled receptor, putative 0.0025 0.0014 0.0016
Echinococcus multilocularis Furin 1 0.3185 0.2392 0.2976
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0011 0.0225
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0002 0.0014
Echinococcus granulosus lamin dm0 0.0027 0.0015 0.0014
Giardia lamblia MRP-like ABC transporter 0.0016 0.0007 0.0016
Brugia malayi G-protein coupled receptor 0.0025 0.0014 0.0013
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0014 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0086 0.006 0.0059
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0002 0.0001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0183 0.0133 0.0132
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0018
Brugia malayi ORL1-like opioid receptor 0.0025 0.0014 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0075
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0026 0.0572
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0008 0.0002 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0025 0.0025
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0086 0.006 0.0059
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0051 0.0033 0.0033
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0011 0.0011
Brugia malayi hypothetical protein 0.0086 0.006 0.006
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0004 0.0004
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.0008 0.0002 0.0002
Schistosoma mansoni alkaline phosphatase 0.0196 0.0143 0.0143
Brugia malayi Muscleblind-like protein 0.018 0.0131 0.013
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.0029
Echinococcus granulosus G protein coupled receptor 139 0.0025 0.0014 0.0013
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0005 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0012 0.0004 0.0076
Plasmodium falciparum flap endonuclease 1 0.0026 0.0015 0.0325
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0017 0.0366
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0052 0.1204
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0026 0.003
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0028 0.063
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0026 0.0572
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0011 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Mycobacterium ulcerans acetyl-CoA synthetase 0.0008 0.0002 0.0014
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3185 0.2392 0.3925
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0183 0.0133 0.0133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0028 0.063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0028 0.0637
Brugia malayi Latrophilin receptor protein 2 0.005 0.0033 0.0032
Leishmania major arginine N-methyltransferase, type I 0.0038 0.0024 0.0527
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0011 0.0225
Echinococcus granulosus potassium large conductance calcium activated 0.0017 0.0008 0.0007
Schistosoma mansoni cript-related 0.0008 0.0002 0.0002
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.0062 0.0061
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0051 0.0051
Schistosoma mansoni lamin 0.0027 0.0015 0.0015
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.0004 0.0005
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0004 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.001 0.0014
Toxoplasma gondii subtilisin SUB8 0.0576 0.0429 1
Leishmania major myo-inositol-1 phosphatase, putative 0.0012 0.0004 0.0076
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0003 0.0002
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0021 0.002
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0014 0.0016
Echinococcus multilocularis lamin dm0 0.0027 0.0015 0.0018
Onchocerca volvulus Bile acid receptor homolog 0.0183 0.0133 0.3093
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.2609 0.1959 0.3213
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0004 0.0003
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0081 0.0057 0.1303
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0018 0.0009 0.0009
Schistosoma mansoni cytochrome P450 0.002 0.0011 0.0011
Giardia lamblia Inositol 5-phosphatase 4 0.0008 0.0002 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0051 0.1155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.001 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0483 0.0359 0.0358
Leishmania major p-glycoprotein e 0.0016 0.0007 0.0142
Toxoplasma gondii bicoid-interacting protein BIN3 0.0038 0.0024 0.0534
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.008 0.1845
Leishmania major hypothetical protein, conserved 0.0032 0.0019 0.0423
Onchocerca volvulus 0.0025 0.0014 0.0307
Onchocerca volvulus 0.0576 0.0429 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0021 0.0011 0.0013
Leishmania major hypothetical protein, conserved 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0014 0.0016
Onchocerca volvulus 0.0008 0.0002 0.0021
Schistosoma mansoni protein kinase 0.002 0.001 0.001
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0114 0.0081 1
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0001 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0012 0.0004 0.0005
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0038 0.0024 0.0037
Brugia malayi Cytochrome P450 family protein 0.0066 0.0045 0.0044
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0012 0.0242
Schistosoma mansoni smad1 5 8 and 0.001 0.0003 0.0003
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0017 0.0008 0.0007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0183 0.0133 0.0132
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0008 0.0019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0008 0.0164
Echinococcus multilocularis G protein coupled receptor 139 0.0025 0.0014 0.0016
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0019 0.0018
Echinococcus granulosus protein arginine methyltransferase 0.0069 0.0048 0.0046
Schistosoma mansoni 60S ribosomal protein L21 0.002 0.001 0.001
Onchocerca volvulus 0.0036 0.0022 0.0498
Schistosoma mansoni inositol monophosphatase 0.0114 0.0081 0.0081
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0012 0.0004 0.0205
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Plasmodium vivax subtilisin-like serine protease, putative 0.0576 0.0429 1
Brugia malayi cation channel family protein 0.0017 0.0008 0.0007
Echinococcus granulosus tachykinin peptides receptor 99D 0.0025 0.0014 0.0013
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0004 0.0075
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0032 0.0031
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0011
Brugia malayi ABC transporter transmembrane region family protein 0.0016 0.0007 0.0006
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0018 0.0009 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0031 0.0037
Schistosoma mansoni steroid hormone receptor ad4bp 0.0183 0.0133 0.0133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Onchocerca volvulus 0.0086 0.006 0.1392
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0123 0.0152
Echinococcus multilocularis musashi 0.0027 0.0015 0.0018
Echinococcus granulosus shaker cognate 0.0018 0.0009 0.0007
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0319 0.0235 0.0234
Leishmania major hypothetical protein, conserved 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Leishmania major trypanothione reductase 0.0049 0.0032 0.0731
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0028 0.0044
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0025 0.0014 0.0013
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0008 0.0001 0.0007
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0025 0.0014 0.0013
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0367 0.0366
Schistosoma mansoni amine GPCR 0.0025 0.0014 0.0014
Leishmania major protein kinase, putative 0.0013 0.0005 0.0097
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis smad 0.001 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0011 0.0225
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0016 0.0007 0.0006
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0002 0.0008
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.001 0.0223
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0183 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0008 0.0002 0.0001
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0017 0.0008 0.0007
Echinococcus granulosus protein arginine N methyltransferase 7 0.0038 0.0024 0.0023
Brugia malayi Furin-like cysteine rich region family protein 0.0366 0.0271 0.027
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0008 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0018 0.0408
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0035 0.0034
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0008 0.0002 0.0001
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0038 0.0024 0.0023
Onchocerca volvulus 0.0058 0.0039 0.0897
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Echinococcus granulosus chromobox protein 2 0.0011 0.0004 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0081 0.0057 0.1303
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0026 0.4378
Schistosoma mansoni hypothetical protein 0.005 0.0033 0.0033
Brugia malayi hypothetical protein 0.0097 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0015 0.0015
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0007 0.0016
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Echinococcus multilocularis expressed conserved protein 0.0112 0.0079 0.0097
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0004 0.0071
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0017 0.0993
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0008 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0001 0.0007
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 0.3351
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0183 0.0133 0.0164
Schistosoma mansoni transient receptor potential channel 0.0017 0.0008 0.0008
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0011 0.0218
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0183 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0008 0.0007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0003 0.0002
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0097 0.0068 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0082 0.1877
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0011 0.0218
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0004 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0008 0.0008
Plasmodium falciparum thioredoxin reductase 0.0049 0.0032 0.0738
Brugia malayi hypothetical protein 0.01 0.0071 0.007
Onchocerca volvulus 0.0025 0.0014 0.0307
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0017 0.0371
Schistosoma mansoni neuropeptide f receptor 76f 0.0025 0.0014 0.0014
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0086 0.006 0.006
Brugia malayi cytochrome P450 0.002 0.0011 0.001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0021 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0038 0.0024 0.0024
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0008 0.0002 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0126 0.009 0.011
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0014 0.0013
Brugia malayi CHD4 protein 0.0013 0.0005 0.0005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0026 0.0572
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.005 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0006
Loa Loa (eye worm) voltage-gated calcium channel 0.0017 0.0008 0.0007
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0576 0.0429 0.0429
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0038 0.0024 0.0527
Echinococcus granulosus g protein coupled receptor 0.0025 0.0014 0.0013
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0008 0.0012
Echinococcus granulosus peptidase Clp S14 family 0.0053 0.0036 0.0034
Schistosoma mansoni patched 1 0.0051 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0576 0.0429 0.0703
Loa Loa (eye worm) hypothetical protein 0.0365 0.027 0.0269
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0011 0.0225
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0018 0.0408
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0008 0.0002 0.0014
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0032 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0008 0.0001 0.0007
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0034 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Brugia malayi nuclear receptor RXR 0.0097 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus neuropeptides capa receptor 0.0025 0.0014 0.0013
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0483 0.0359 0.0358
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0576 0.0429 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0001
Echinococcus granulosus phd:f box containing protein 0.0032 0.0019 0.0018
Entamoeba histolytica multidrug resistance protein, putative 0.0016 0.0007 0.0381
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0004 0.0075
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0038 0.0024 0.1417
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0002 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0576 0.0429 0.0428
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0008 0.0007
Trichomonas vaginalis Phospholipase C precursor, putative 0.0008 0.0002 0.0001
Plasmodium vivax steroid dehydrogenase, putative 0.0008 0.0001 0.0007
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0018 0.0009 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0039 0.0038
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0009 0.0007
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0172
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0081 0.1873
Brugia malayi Dopamine receptor 0.0025 0.0014 0.0013
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0014 0.0016
Schistosoma mansoni vesicular amine transporter 0.0018 0.0009 0.0009
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Brugia malayi CHE-14 protein 0.0051 0.0034 0.0033
Plasmodium falciparum glutathione reductase 0.0049 0.0032 0.0738
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0008 0.0166
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Giardia lamblia Replication factor C, subunit 1 0.0012 0.0004 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0025 0.0014 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0097 0.0068 0.0067
Toxoplasma gondii hypothetical protein 0.0028 0.0017 0.0366
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0001 0.0007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Treponema pallidum DNA ligase (lig) 0.0012 0.0004 0.0516
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0104 0.0074 0.4574
Leishmania major subtilisin-like serine peptidase 0.0576 0.0429 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0041 0.004
Onchocerca volvulus 0.01 0.0071 0.1631
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0009 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0025 0.0014 0.0013
Toxoplasma gondii hypothetical protein 0.0097 0.0068 0.157
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0005 0.0097
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Schistosoma mansoni calcium-activated potassium channel 0.0017 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0183 0.0133 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.132
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Echinococcus multilocularis peptidase Clp (S14 family) 0.0053 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.8103 0.6093 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Echinococcus multilocularis transient receptor potential gamma protein 0.0017 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0011 0.0218
Schistosoma mansoni nuclear hormone receptor 0.0086 0.006 0.006
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0017 0.0008 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0183 0.0133 0.0133
Echinococcus granulosus hypothetical protein 0.0017 0.0008 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Echinococcus granulosus neuroendocrine convertase 2 0.8376 0.6299 0.6299
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3185 0.2392 0.3925
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0086 0.006 0.006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Echinococcus multilocularis conserved hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0002 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0017 0.0016
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0172
Brugia malayi hypothetical protein 0.003 0.0018 0.0017
Echinococcus multilocularis Smad4 0.001 0.0003 0.0002
Echinococcus multilocularis transfer RNA-Gly 0.0018 0.0009 0.0009
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0004 0.0004
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.0001 0.0001
Brugia malayi Inositol-1 0.0114 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0001
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis lamin 0.0027 0.0015 0.0018
Treponema pallidum NADH oxidase 0.0017 0.0008 0.122
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0001
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0069 0.0048 0.0058
Onchocerca volvulus 0.0008 0.0002 0.0016
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Brugia malayi hypoxia-induced factor 1 0.0149 0.0107 0.0107
Trichomonas vaginalis inositol monophosphatase, putative 0.0114 0.0081 0.0132
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0009 0.0009
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) Smad1 0.001 0.0003 0.0002
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0011 0.0218
Trichomonas vaginalis glycogen phosphorylase, putative 0.0219 0.016 0.0261
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0031 0.003
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0002 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0002 0.0001
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0002 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0045 0.0044
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0102 0.0072 0.0072
Echinococcus multilocularis dro:myosuppressin receptor 0.0025 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus Furin 1 0.3185 0.2392 0.2392
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3185 0.2392 0.3925
Loa Loa (eye worm) hypothetical protein 0.0157 0.0113 0.0112
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Echinococcus granulosus calcium activated potassium channel 0.0017 0.0008 0.0007
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0107 0.0076 0.0075
Entamoeba histolytica glycogen phosphorylase, putative 0.0095 0.0067 0.4119
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0014 0.0013
Echinococcus granulosus glycogen phosphorylase 0.0219 0.016 0.0159
Mycobacterium ulcerans hypothetical protein 0.0029 0.0017 0.0369
Brugia malayi PAS domain containing protein 0.0048 0.0032 0.0031
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0008 0.0002 0.0001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0166
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0041 0.0929
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0011 0.0218
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0008 0.0002 0.0008
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.0004 0.0005
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0183 0.0133 0.0164
Echinococcus multilocularis Chromo domain 0.0011 0.0004 0.0003
Echinococcus granulosus nuclear receptor nhr 48 0.0086 0.006 0.0059
Schistosoma mansoni hypothetical protein 0.0353 0.0261 0.0261
Brugia malayi Serotonin receptor 0.0025 0.0014 0.0013
Brugia malayi Carm1-pending protein 0.0038 0.0024 0.0023
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0008 0.0008
Schistosoma mansoni multidrug resistance protein 0.0016 0.0007 0.0007
Schistosoma mansoni adenoreceptor 0.0025 0.0014 0.0014
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0085 0.0084
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0319 0.0235 0.0291
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0008 0.0008
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0011 0.0218
Brugia malayi hypothetical protein 0.0086 0.006 0.006
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0008 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0183 0.0133 0.0133
Entamoeba histolytica hypothetical protein 0.0012 0.0004 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0183 0.0133 0.0132
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0011 0.0009
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0002 0.0021
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0005 0.0006
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0038 0.0024 0.0028
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0051 0.1161
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0183 0.0133 0.0132
Giardia lamblia Glycogen phosphorylase 0.0219 0.016 0.0431
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.5191 0.3902 0.3901
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0085 0.5259
Schistosoma mansoni hypothetical protein 0.0014 0.0006 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0008 0.0002 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0025 0.0565
Schistosoma mansoni protein kinase 0.002 0.001 0.001
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0016 0.0007 0.0142
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0038 0.0024 0.0527
Toxoplasma gondii subtilisin SUB12 0.0576 0.0429 1
Schistosoma mansoni neuropeptide receptor 0.0025 0.0014 0.0014
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3185 0.2392 0.3925
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0033 0.0032
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0011 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Leishmania major cytochrome p450-like protein 0.002 0.0011 0.0218
Schistosoma mansoni glycogen phosphorylase 0.0219 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0025 0.0014 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0104 0.0103
Onchocerca volvulus 0.0092 0.0064 0.1482
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0183 0.0133 0.0132
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0003 0.0002
Echinococcus granulosus multidrug resistance associated protein 7 0.0016 0.0007 0.0006
Mycobacterium leprae Possible secreted protease 0.0576 0.0429 1
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0318
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0005
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0007 0.0381
Schistosoma mansoni retinal dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0017 0.0016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0028 0.0637
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0011 0.0228
Loa Loa (eye worm) cytochrome P450 0.002 0.0011 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0018 0.0401
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0097 0.0068 0.0067
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0086 0.006 0.006
Brugia malayi hypothetical protein 0.0365 0.027 0.0269
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Schistosoma mansoni transient receptor potential channel 4 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Loa Loa (eye worm) Carm1-pending protein 0.0038 0.0024 0.0023
Schistosoma mansoni coup transcription factor 0.0183 0.0133 0.0133
Echinococcus granulosus tumor protein p63 0.0334 0.0247 0.0246
Brugia malayi Pre-SET motif family protein 0.0206 0.0151 0.015
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0017 0.0016
Echinococcus multilocularis serotonin receptor 0.0025 0.0014 0.0016
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0196 0.0143 0.0142
Echinococcus granulosus multidrug resistance associated protein 1 0.0016 0.0007 0.0006
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0009
Mycobacterium tuberculosis Conserved protein 0.0043 0.0028 0.0637
Echinococcus multilocularis neuropeptide s receptor 0.0984 0.0736 0.0914
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0025 0.0014 0.0013
Brugia malayi Smad1 0.001 0.0003 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0017 0.0369
Loa Loa (eye worm) oxidoreductase 0.0008 0.0002 0.0001
Schistosoma mansoni RAR-like nuclear receptor 0.0183 0.0133 0.0133
Onchocerca volvulus 0.0027 0.0015 0.0341
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0008 0.0002 0.0023
Schistosoma mansoni opsin-like receptor 0.0025 0.0014 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0032 0.0731
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0576 0.0429 0.0428
Loa Loa (eye worm) ion channel NompC 0.0017 0.0008 0.0007
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0004 0.0082
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0002 0.0008
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0004 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0172
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0008 0.0001 0.0007
Echinococcus multilocularis neuropeptide FF receptor 2 0.0025 0.0014 0.0016
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0002 0.0016
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0008 0.0164
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0006 0.0005
Entamoeba histolytica glycogen phosphorylase, putative 0.0219 0.016 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0053 0.0036 0.0803
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0025 0.0014 0.0013
Brugia malayi jmjC domain containing protein 0.0032 0.0019 0.0018
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0011 0.0218
Giardia lamblia hypothetical protein 0.0008 0.0002 0.0001
Echinococcus multilocularis voltage gated potassium channel 0.0025 0.0014 0.0016
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0172
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0019 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Brugia malayi nuclear receptor NHR-88 0.0086 0.006 0.006
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0005 0.0097
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0017 0.0016
Echinococcus granulosus somatostatin receptor 0.0025 0.0014 0.0013
Brugia malayi tailless protein 0.0086 0.006 0.006
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0033 0.0039
Schistosoma mansoni rotamase 0.004 0.0026 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0011 0.0225
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0113 0.0081 0.008
Echinococcus multilocularis glycogen phosphorylase 0.0219 0.016 0.0198
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0025 0.0014 0.0014
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0008 0.0002 0.0014
Schistosoma mansoni two-pore calcium channel 0.0017 0.0008 0.0008
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0012 0.0004 0.0076
Echinococcus granulosus muscleblind protein 0.018 0.0131 0.013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0007
Giardia lamblia ABC transporter, putative 0.0016 0.0007 0.0016
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0114 0.0081 0.5036
Brugia malayi Death domain containing protein 0.0014 0.0006 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.002 0.001 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0086 0.006 0.0074
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0008 0.0164
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0028 0.063
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0012 0.0004 0.0084
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0002 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0086 0.006 0.006
Schistosoma mansoni carbonyl reductase 0.0008 0.0001 0.0001
Echinococcus multilocularis sodium channel protein 0.0017 0.0008 0.0008
Echinococcus granulosus geminin 0.0353 0.0261 0.026
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0002 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0051 0.1155
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0053 0.0036 0.081
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0032 0.0738
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0026 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0027 0.0027
Schistosoma mansoni amine GPCR 0.0025 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0011
Echinococcus granulosus chromobox protein 1 0.0011 0.0004 0.0003
Toxoplasma gondii subtilisin SUB9 0.0576 0.0429 1
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0166
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0014 0.0016
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0002 0.0021
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0026 0.0025
Schistosoma mansoni smad1 5 8 and 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Schistosoma mansoni biogenic amine receptor 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.008 0.1845
Echinococcus granulosus expressed conserved protein 0.0112 0.0079 0.0078
Brugia malayi photoreceptor-specific nuclear receptor 0.0183 0.0133 0.0132
Schistosoma mansoni neutral sphingomyelinase 0.0008 0.0002 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0005 0.0006
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0005 0.0004
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0041 0.0936
Onchocerca volvulus Putative neutral sphingomyelinase 0.0008 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0011 0.0218
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0012 0.0004 0.0004
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0017 0.0369
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0011 0.0011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0089 0.2065
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0012 0.0004 0.0076
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0002 0.0001
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0009 0.0008
Brugia malayi nuclear hormone receptor 0.0183 0.0133 0.0132
Brugia malayi hypothetical protein 0.0097 0.0068 0.0067
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0033 0.0039
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0005 0.0081
Echinococcus granulosus dro:myosuppressin receptor 0.0025 0.0014 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0017 0.0993
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0005 0.0006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0015 0.0015
Brugia malayi celfurPC protein 1.0685 0.8037 0.8037
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0011 0.0225
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0018 0.0408
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0008 0.0002 0.0014
Schistosoma mansoni protein arginine n-methyltransferase 0.0038 0.0024 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0011 0.0013
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0576 0.0429 1
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Schistosoma mansoni biogenic amine receptor 0.0025 0.0014 0.0014
Schistosoma mansoni amine GPCR 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0002 0.0021
Trypanosoma brucei p-glycoprotein 0.0016 0.0007 0.0142
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0015 0.0318
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0011 0.0218
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0002 0.0001
Chlamydia trachomatis endonuclease IV 0.0076 0.0052 0.308
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.0082 0.1883
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0028 0.0637
Brugia malayi Serotonin receptor 0.0025 0.0014 0.0013
Echinococcus granulosus peptide allatostatin:somatostatin 0.0025 0.0014 0.0013
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0008 0.0166
Schistosoma mansoni myo inositol monophosphatase 0.0012 0.0004 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0004 0.0004
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0005 0.0085
Brugia malayi Nuclear hormone receptor E75 0.0086 0.006 0.006
Trichomonas vaginalis rotamase, putative 0.0039 0.0025 0.0039
Brugia malayi G-protein coupled receptor 0.0025 0.0014 0.0013
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0008 0.0008
Brugia malayi Cyclic-nucleotide gated cation channel 0.0021 0.0011 0.0011
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0005 0.0081
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0011 0.0011
Plasmodium vivax SET domain protein, putative 0.003 0.0018 0.0405
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0021 0.0011 0.001
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.0001 0.0007
Echinococcus granulosus two pore calcium channel protein 1 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 1.3293 1 1
Echinococcus granulosus sodium leak channel non selective protein 0.0017 0.0008 0.0007
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.0623 0.0623
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0017 0.0371
Schistosoma mansoni lamin 0.0027 0.0015 0.0015
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0041 0.0929
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Loa Loa (eye worm) TK/EGFR protein kinase 0.0366 0.0271 0.027
Brugia malayi Cytochrome P450 family protein 0.0029 0.0017 0.0016
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0012 0.0249
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0008 0.0007
Schistosoma mansoni kinase 0.0058 0.0039 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0183 0.0133 0.0132
Echinococcus multilocularis two pore calcium channel protein 2 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0036 0.0022 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Toxoplasma gondii subtilisin SUB1 0.0576 0.0429 1
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0011 0.0218
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0001 0.0007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0166
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 0.692
Loa Loa (eye worm) hypothetical protein 0.0161 0.0117 0.0116
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0006 0.0006
Echinococcus multilocularis muscleblind protein 0.018 0.0131 0.0162
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0004 0.0004
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0008 0.0002 0.0001
Toxoplasma gondii subtilisin SUB10 0.0576 0.0429 1
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.132
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0113 0.0081 0.1854
Schistosoma mansoni survival motor neuron protein 0.0058 0.0039 0.0039
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0023
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0026 0.0025
Loa Loa (eye worm) multidrug resistance-associated protein 0.0012 0.0005 0.0004
Onchocerca volvulus 0.0008 0.0001 0.0007
Toxoplasma gondii hypothetical protein 0.0017 0.0008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium ulcerans hypothetical protein 0.0043 0.0028 0.063
Echinococcus multilocularis sex peptide receptor 0.0025 0.0014 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0011 0.0218
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0576 0.0429 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0183 0.0133 0.0132
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0003 0.0002
Echinococcus granulosus thyroid hormone receptor alpha 0.0086 0.006 0.0059
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0008 0.0172
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0011 0.0218
Brugia malayi Dopamine receptor protein 1 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0011 0.0225
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Brugia malayi GnHR receptor homolog 0.0025 0.0014 0.0013
Brugia malayi CXXC zinc finger family protein 0.0035 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0051 0.0062
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0086 0.006 0.0074
Echinococcus granulosus Glycosyl transferase family 35 0.0219 0.016 0.0159
Loa Loa (eye worm) hypothetical protein 0.018 0.0131 0.013
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0028 0.0044
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0026 0.0066
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0015 0.0015
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0003 0.0002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0006 0.0005
Loa Loa (eye worm) nuclear hormone receptor 0.0086 0.006 0.006
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0011 0.0218
Echinococcus multilocularis voltage dependent calcium channel 0.0319 0.0235 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0082 0.0082
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.021 0.0209
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0011 0.0228
Plasmodium vivax exodeoxyribonuclease III, putative 0.0008 0.0002 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0017 0.0008 0.0008
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0008 0.0008
Schistosoma mansoni retinoic acid receptor RXR 0.0183 0.0133 0.0133
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Brugia malayi neuropeptide F receptor 0.0025 0.0014 0.0013
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.001 0.001
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0011 0.0218
Brugia malayi Melatonin receptor type 1A 0.0025 0.0014 0.0013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0028 0.0028
Brugia malayi Uncoordinated protein 44 0.0014 0.0006 0.0005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.3185 0.2392 0.3925
Leishmania major hypothetical protein, unknown function 0.0017 0.0008 0.0156
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.0623 0.0773
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0002 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0011 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0011 0.0225
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0081 0.1873
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0025 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni cpg binding protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Onchocerca volvulus 0.0025 0.0014 0.0307
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0011 0.0226
Onchocerca volvulus 0.0025 0.0014 0.0307
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0576 0.0429 1
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0008 0.0002 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0025 0.0014 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis membrane bound transcription factor site 1 0.0576 0.0429 0.0533
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0011 0.0218
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0051 0.0051
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0025 0.0014 0.0013
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0036 0.0022 0.0022
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.0082 0.0081
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0005 0.0004
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.0001 0.0001
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0002 0.0014
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0002 0.0014
Schistosoma mansoni neuropeptide receptor 0.0025 0.0014 0.0014
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.2609 0.1959 0.3213
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0011 0.0228
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0576 0.0429 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0119 0.0085 0.0104
Echinococcus granulosus inositol monophosphatase 0.0012 0.0004 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.0025 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0204 0.4753
Echinococcus granulosus lamin 0.0027 0.0015 0.0014
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0069 0.0048 0.0076
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.0001 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Echinococcus multilocularis multidrug resistance associated protein 7 0.0016 0.0007 0.0008
Toxoplasma gondii endonuclease IV APN 0.0076 0.0052 0.1204
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0008 0.0007
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0022 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0011 0.0225
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0001 0.0007
Brugia malayi Probable ClpP-like protease 0.0081 0.0057 0.0056
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0196 0.0143 0.0177
Toxoplasma gondii subtilisin SUB2 0.0576 0.0429 1
Giardia lamblia High cysteine membrane protein Group 2 0.4918 0.3696 1
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.0001 0.0007
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0005 0.0006
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0002 0.0023
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.0011 0.0004 0.0172
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0011 0.001
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0089 0.2065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0016
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0012 0.0004 0.0076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0097 0.0068 0.0068
Leishmania major pentamidine resistance protein 1 0.0016 0.0007 0.0142
Leishmania major hypothetical protein, conserved 0.0043 0.0028 0.063
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0019 0.0018
Brugia malayi Protein cec-1. 0.0011 0.0004 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0052 0.1204
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0005 0.0085
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0005 0.0006
Onchocerca volvulus 0.0025 0.0014 0.0307
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Brugia malayi hypothetical protein 0.0129 0.0093 0.0092
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0009 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Schistosoma mansoni zinc finger protein 0.0086 0.006 0.006
Loa Loa (eye worm) heterochromatin protein 1 0.0011 0.0004 0.0003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0011 0.0218
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0023
Trypanosoma cruzi FHA domain containing protein, putative 0.0012 0.0004 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Brugia malayi AKH receptor 0.0025 0.0014 0.0013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.008 0.1839
Plasmodium vivax glutathione reductase, putative 0.0049 0.0032 0.0738
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0011 0.0218
Schistosoma mansoni jumonji domain containing protein 0.0119 0.0085 0.0085
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0012 0.0005 0.0029
Brugia malayi ecdysone receptor 0.0086 0.006 0.006
Brugia malayi jmjC domain containing protein 0.0121 0.0086 0.0085
Echinococcus granulosus smad 0.001 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0024
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0008 0.0007
Echinococcus granulosus transient receptor potential gamma protein 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.0001 0.0007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0183 0.0133 0.0133
Toxoplasma gondii subtilisin SUB5 0.0576 0.0429 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0053 0.0036 0.081
Onchocerca volvulus Sepiapterin reductase homolog 0.0008 0.0001 0.0007
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0051 0.1162
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0003 0.0002
Echinococcus granulosus Ankyrin 0.0014 0.0006 0.0005
Toxoplasma gondii hypothetical protein 0.0017 0.0008 0.0164
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0017 0.0369
Brugia malayi steroid hormone receptor 0.0183 0.0133 0.0132
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0008 0.0008
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0001 0.0007
Onchocerca volvulus 0.0025 0.0014 0.0307
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.0012 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0011 0.0218
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0051 0.0049
Brugia malayi nuclear hormone receptor family member odr-7 0.0086 0.006 0.006
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0002 0.0001
Schistosoma mansoni transient receptor potential channel 0.0017 0.0008 0.0008
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0367 0.0455
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 0.1296
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0183 0.0133 0.0133
Brugia malayi Subtilase family protein 0.0576 0.0429 0.0428
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0002 0.0001
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0008 0.0002 0.0008
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0166
Onchocerca volvulus Neuropeptide F receptor homolog 0.0025 0.0014 0.0307
Loa Loa (eye worm) glutathione reductase 0.0049 0.0032 0.0032
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0008 0.0173
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Trypanosoma cruzi subtilisin peptidase 0.0576 0.0429 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0041 0.0929
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0002 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0025 0.0014 0.0014
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0002 0.0016
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0017 0.0008 0.0007
Echinococcus multilocularis epidermal growth factor receptor 0.0366 0.0271 0.0336
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Leishmania major ABC-thiol transporter 0.0016 0.0007 0.0142
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0008 0.0002 0.0023
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0183 0.0133 0.0164
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0039 0.0025 0.0024
Schistosoma mansoni pap-inositol-14-phosphatase 0.0012 0.0004 0.0004
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0008 0.0008
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0012 0.0004 0.0076
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0023
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0003 0.0002
Trichomonas vaginalis hypothetical protein 0.2609 0.1959 0.3213
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0019 0.0019
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0017 0.0008 0.0008
Schistosoma mansoni opsin-like receptor 0.0025 0.0014 0.0014
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0015 0.0325
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0038 0.0024 0.0527
Brugia malayi proprotein convertase 2 0.8376 0.6299 0.6299
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0001 0.0007
Echinococcus granulosus neuropeptide s receptor 0.0984 0.0736 0.0735
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0028 0.0027
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0003 0.0002
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0025 0.1501
Brugia malayi hypothetical protein 0.0104 0.0074 0.0073
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0028 0.0044
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0019 0.0018
Schistosoma mansoni voltage-gated ion channel 0.0017 0.0008 0.0008
Schistosoma mansoni DNA ligase IV 0.0012 0.0004 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0026 0.0572
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0017 0.0369
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0008 0.0002 0.0008
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0017 0.0008 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0007 0.0016
Echinococcus granulosus ryanodine receptor 44f 0.0017 0.0008 0.0007
Schistosoma mansoni multidrug resistance protein 0.0016 0.0007 0.0007
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0021 0.0011 0.001
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0011 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Echinococcus granulosus FTZ F1 alpha 0.0183 0.0133 0.0132
Echinococcus granulosus alpha 1A adrenergic receptor 0.0025 0.0014 0.0013
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.0082 0.1877
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0002 0.0001
Brugia malayi hypothetical protein 0.002 0.001 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0014 0.0014
Schistosoma mansoni site-1 peptidase (S08 family) 0.0576 0.0429 0.0429
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0011 0.0004 0.0071
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0008 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0081 0.1873
Echinococcus granulosus g protein coupled receptor 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0011 0.0225
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus lysine specific demethylase 5A 0.0121 0.0086 0.0085
Schistosoma mansoni single-minded 0.0048 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0119 0.0085 0.0084
Echinococcus multilocularis voltage dependent calcium channel 0.0319 0.0235 0.0291
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0008 0.0173
Onchocerca volvulus 0.0043 0.0028 0.0637
Trichomonas vaginalis glycogen phosphorylase, putative 0.0219 0.016 0.0261
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0012 0.0249
Echinococcus granulosus death domain containing protein 0.0014 0.0006 0.0005
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0008 0.0001 0.0007
Brugia malayi Nuclear hormone receptor E75 0.0086 0.006 0.006
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Schistosoma mansoni carbonyl reductase 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni topbp1 0.0012 0.0004 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0028 0.0028
Echinococcus granulosus two pore calcium channel protein 2 0.0017 0.0008 0.0007
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1657 0.1243 0.1545
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.0082 0.0081
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0081 0.0057 0.0069
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0017 0.0369
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0114 0.0081 0.1873
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0017 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0025 0.0014 0.0014
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0008 0.0008
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0051 0.1155
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0006 0.0006
Leishmania major endonuclease/exonuclease protein-like protein 0.0008 0.0002 0.0008
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0011 0.0218
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Onchocerca volvulus 0.0025 0.0014 0.0307
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Toxoplasma gondii transporter, cation channel family protein 0.0113 0.0081 0.186
Brugia malayi Dopamine receptor protein 2 0.0025 0.0014 0.0013
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0069 0.0048 0.0048
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0011 0.0218
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0025 0.0014 0.0013
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.0037 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0097 0.0068 0.0067
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0008 0.0884
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Onchocerca volvulus 0.0029 0.0017 0.0376
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0011 0.0218
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0015 0.0855
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0006
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0006 0.0006
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0008 0.0001 0.0007
Mycobacterium tuberculosis Probable dehydrogenase 0.0008 0.0001 0.0007
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0008 0.0008
Loa Loa (eye worm) ryanodine receptor 0.0017 0.0008 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0032 0.0039
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0019 0.0018
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0019 0.043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0183 0.0133 0.0132
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0104 0.0074 0.1701
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0003 0.0003
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0008 0.0001 0.0007
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0008 0.0164
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0089 0.2065
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0086 0.0086
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0017 0.0008 0.0007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0026 0.1539
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0009 0.0009
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0576 0.0429 1
Brugia malayi putative neuropeptide receptor 0.0025 0.0014 0.0013
Echinococcus granulosus neuropeptide receptor 0.0025 0.0014 0.0013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0086 0.006 0.0074
Brugia malayi G protein-coupled receptor 0.0025 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0183 0.0133 0.0132
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0002 0.0021
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0025 0.0014 0.0013
Mycobacterium ulcerans beta-lactamase 0.0043 0.0028 0.063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.001 0.0014
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0183 0.0133 0.0132
Brugia malayi DKFZp564C0469 protein 0.0012 0.0004 0.0004
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0008 0.0002 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0017 0.0376
Echinococcus multilocularis serotonin receptor 0.0025 0.0014 0.0016
Entamoeba histolytica ABC transporter, putative 0.0016 0.0007 0.0381
Loa Loa (eye worm) hypothetical protein 0.0051 0.0034 0.0033
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0025 0.0014 0.0307
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0166
Echinococcus granulosus single minded 2 0.0039 0.0025 0.0024
Onchocerca volvulus 0.0183 0.0133 0.3093
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0183 0.0133 0.0132
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0009 0.0009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0014 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0025 0.0014 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0006 0.0005
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0001 0.0007
Mycobacterium tuberculosis Probable reductase 0.0112 0.008 0.1845
Loa Loa (eye worm) inositol-1 0.0114 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0576 0.0429 0.0703
Echinococcus multilocularis alkaline phosphatase 0.0196 0.0143 0.0177
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0014 0.0016
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0038 0.0024 0.0527
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0002 0.0021
Brugia malayi jmjC domain containing protein 0.0032 0.0019 0.0018
Trichomonas vaginalis esterase, putative 0.0043 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0014 0.0016
Echinococcus granulosus microtubule associated protein 2 0.0833 0.0623 0.0621
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0018
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0006 0.0123
Brugia malayi orphan nuclear receptor NR2E1 0.0086 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0022 0.0022
Onchocerca volvulus 0.0012 0.0005 0.0093
Echinococcus granulosus hypothetical protein 0.0025 0.0014 0.0013
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0005 0.0089
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0008 0.0173
Echinococcus granulosus membrane bound transcription factor site 1 0.0576 0.0429 0.0428
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Schistosoma mansoni ryanodine receptor related 0.0017 0.0008 0.0008
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0008 0.0166
Onchocerca volvulus 0.01 0.0071 0.1631
Brugia malayi Stress-activated protein kinase jnk-1 0.0126 0.009 0.0089
Schistosoma mansoni hypothetical protein 0.005 0.0033 0.0033
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0009 0.0009
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0005 0.0004
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0025 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0576 0.0429 0.0703
Brugia malayi glutathione reductase 0.0049 0.0032 0.0032
Onchocerca volvulus 0.0025 0.0014 0.0307
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0012 0.0004 0.0075
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus g protein coupled receptor 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Schistosoma mansoni myosin xvIII 0.0025 0.0014 0.0014
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0038 0.0024 0.0023
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0017 0.0376
Loa Loa (eye worm) hypothetical protein 0.005 0.0033 0.0032
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0012 0.0005 0.0435
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0113 0.0112
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0022 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0196 0.0143 0.0142
Plasmodium vivax subtilisin-like protease 1 0.0576 0.0429 1
Onchocerca volvulus 0.0008 0.0001 0.0007
Loa Loa (eye worm) endoprotease bli-4 1.3293 1 1
Onchocerca volvulus 0.0025 0.0014 0.0307
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0023
Echinococcus multilocularis multidrug resistance associated protein 1 0.0016 0.0007 0.0008
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0017 0.0008 0.0007
Onchocerca volvulus 0.0025 0.0014 0.0307
Echinococcus multilocularis multidrug resistance associated protein 4 0.0012 0.0005 0.0004
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0069 0.0048 0.0048
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.2609 0.1959 0.3213
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Schistosoma mansoni ap endonuclease 0.004 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0038 0.0024 0.0534
Schistosoma mansoni glycogen phosphorylase 0.0219 0.016 0.016
Onchocerca volvulus 0.0025 0.0014 0.0307
Echinococcus multilocularis protein dispatched 1 0.0058 0.0039 0.0047
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0028 0.0044
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0025 0.0014 0.0016
Echinococcus multilocularis potassium voltage gated channel protein 0.0039 0.0025 0.0029
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0067 0.0046 0.0073
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0119 0.0085 0.0084
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0031 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.132
Echinococcus multilocularis geminin 0.0353 0.0261 0.0324
Brugia malayi Protein kinase domain containing protein 0.0015 0.0007 0.0006
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus methyltransferase protein 5 0.0038 0.0024 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0025 0.0014 0.0014
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0104 0.0074 0.1701
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0019 0.0019
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.002 0.001 0.0009
Schistosoma mansoni chromobox protein 0.0011 0.0004 0.0004
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0319 0.0235 0.0234
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0576 0.0429 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0017 0.0369
Plasmodium vivax acetyl-CoA synthetase, putative 0.0008 0.0002 0.0021
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0002 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0085 0.0104
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0008 0.0012
Echinococcus granulosus voltage dependent calcium channel 0.0319 0.0235 0.0234
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0033 0.0032
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0004 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0011 0.0011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0018 0.0021
Loa Loa (eye worm) proprotein convertase 2 0.3185 0.2392 0.2392
Chlamydia trachomatis glycogen phosphorylase 0.0219 0.016 1
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0004 0.0071
Onchocerca volvulus 0.0008 0.0001 0.0007
Schistosoma mansoni hypothetical protein 0.0058 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0028 0.063
Onchocerca volvulus 0.0008 0.0001 0.0007
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0022 0.0026
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0012 0.0458
Mycobacterium leprae Possible regulatory protein 0.0012 0.0005 0.0085
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0005 0.0081
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0011 0.0218
Loa Loa (eye worm) hypothetical protein 0.0129 0.0093 0.0092
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0018 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0015 0.0037
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0004 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0025 0.0014 0.0014
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Schistosoma mansoni hypothetical protein 0.0049 0.0032 0.0032
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.01 0.0071 0.007
Echinococcus multilocularis ryanodine receptor 44f 0.0017 0.0008 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0011 0.0017
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0019 0.0423
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0011
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0113 0.0112
Plasmodium vivax JmjC domain containing protein 0.0032 0.0019 0.043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0009 0.0007
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0025 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Giardia lamblia Hypothetical protein 0.0012 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0034 0.0054
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0009 0.0009
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0008 0.0002 0.0037
Schistosoma mansoni inositol monophosphatase 0.0114 0.0081 0.0081
Mycobacterium tuberculosis Monophosphatase CysQ 0.0012 0.0004 0.0083
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0007
Loa Loa (eye worm) TYRA-2 protein 0.0025 0.0014 0.0013
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0011 0.0218
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0031 0.0031
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Mycobacterium tuberculosis Conserved protein 0.0043 0.0028 0.0637
Mycobacterium leprae conserved hypothetical protein 0.002 0.001 0.0216
Brugia malayi larval opioid receptor 0.0025 0.0014 0.0013
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.3185 0.2392 0.2392
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Onchocerca volvulus 0.0025 0.0014 0.0307
Echinococcus granulosus Chromo domain 0.0011 0.0004 0.0003
Entamoeba histolytica hypothetical protein 0.0036 0.0022 0.132
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0051 0.1155
Schistosoma mansoni hypothetical protein 0.0049 0.0032 0.0032
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Schistosoma mansoni glycogen phosphorylase 0.0095 0.0067 0.0067
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0025 0.0014 0.0016
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0089 0.2059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0183 0.0133 0.0132
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.0107 0.0107
Schistosoma mansoni voltage-dependent calcium channel 0.0017 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0183 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis nibrin 0.0012 0.0004 0.0004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0081 0.0057 0.1296
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0005 0.0005
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0016 0.0007 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0011 0.0225
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0086 0.006 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0319 0.0235 0.0235
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.002 0.0011 0.001
Echinococcus multilocularis Glycosyl transferase, family 35 0.0219 0.016 0.0198
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0008 0.0002 0.0014
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0086 0.0086
Plasmodium falciparum subtilisin-like protease 3 0.0576 0.0429 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0011 0.0218
Brugia malayi ecdysteroid receptor 0.0183 0.0133 0.0132
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0123 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0011 0.0225
Schistosoma mansoni nuclear receptor 0.0086 0.006 0.006
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0022 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0005 0.0004
Trypanosoma brucei subtilisin peptidase 0.0576 0.0429 1
Brugia malayi topoisomerase 0.0012 0.0004 0.0004
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0008 0.0007
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0196 0.0143 0.0177
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0001 0.0007
Echinococcus multilocularis neuropeptides capa receptor 0.0025 0.0014 0.0016
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0008 0.0008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0183 0.0133 0.3093
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0025 0.0014 0.0016
Brugia malayi beta-lactamase 0.0043 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0129 0.0093 0.0092
Trypanosoma cruzi multidrug resistance protein E, putative 0.0016 0.0007 0.0142
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0034 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0004 0.0075
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0008 0.0007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0001
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0017 0.0008 0.0008
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0032 0.0737
Mycobacterium ulcerans endonuclease IV 0.0076 0.0052 0.1197
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0095 0.0067 0.1538
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0081 0.0057 0.1296
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0025 0.0014 0.0016
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0069 0.0048 0.0076
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0012 0.0004 0.0205
Schistosoma mansoni ap endonuclease 0.004 0.0026 0.0026
Brugia malayi neuropeptide F receptor 0.0025 0.0014 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Schistosoma mansoni synaptojanin 0.0008 0.0002 0.0002
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0062 0.0062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0086 0.006 0.0059
Onchocerca volvulus Glycogen phosphorylase homolog 0.0219 0.016 0.3724
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Echinococcus multilocularis tumor protein p63 0.0334 0.0247 0.0306
Schistosoma mansoni thyroid hormone receptor 0.0183 0.0133 0.0133
Schistosoma mansoni voltage-gated cation channel 0.0319 0.0235 0.0235
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0183 0.0133 0.0132
Onchocerca volvulus 0.0008 0.0002 0.0021
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0004 0.0005
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0025 0.0014 0.0016
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0038 0.0024 0.0037
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0041 0.005
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0017 0.0008 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0025 0.0014 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Leishmania major protein kinase, putative 0.0018 0.0009 0.0182
Mycobacterium leprae Probable monophosphatase 0.0012 0.0004 0.0076
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0052 0.1203
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0011 0.0225
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0025 0.0558
Trichomonas vaginalis conserved hypothetical protein 0.0576 0.0429 0.0703
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0017 0.0359
Trypanosoma brucei RNA editing exonuclease 2 0.0008 0.0002 0.0008
Schistosoma mansoni growth hormone secretagogue receptor 0.0025 0.0014 0.0014
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0025 0.0014 0.0014
Brugia malayi hypothetical protein 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0102 0.0072 0.1669
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0002 0.0001
Schistosoma mansoni neuropeptide receptor 0.0025 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0012 0.0004 0.0084
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0051 0.0033 0.0032
Brugia malayi nuclear hormone receptor family member nhr-6 0.0086 0.006 0.006
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0082 0.1877
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0008 0.0002 0.0008
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0015 0.0014
Echinococcus multilocularis 0.002 0.0011 0.0012
Brugia malayi nuclear receptor RXR 0.0086 0.006 0.006
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0008 0.0001 0.0007
Schistosoma mansoni tyrosine kinase 0.0366 0.0271 0.0271
Mycobacterium ulcerans monophosphatase CysQ 0.0012 0.0004 0.0076
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0008 0.0001 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.8103 0.6093 0.7582
Echinococcus granulosus expressed protein 0.004 0.0026 0.0025
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0007 0.0381
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0104 0.0103
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0166
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0026 0.3055
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0319 0.0235 0.0234
Loa Loa (eye worm) hypothetical protein 0.0097 0.0068 0.0067
Plasmodium falciparum steroid dehydrogenase, putative 0.0008 0.0001 0.0007
Leishmania major pantothenate kinase subunit, putative 0.0009 0.0002 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0183 0.0133 0.0133
Echinococcus granulosus serotonin receptor 0.0025 0.0014 0.0013
Schistosoma mansoni furin-1 (S08 family) 0.5767 0.4336 0.4336
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0006 0.0005
Onchocerca volvulus 0.0365 0.027 0.6285
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0011 0.0225
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0011
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0005 0.0085
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0016
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Schistosoma mansoni alpha-1 adrenergic receptor 0.0025 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Echinococcus granulosus voltage gated hydrogen channel 1 0.0017 0.0008 0.0007
Schistosoma mansoni opsin-like receptor 0.0025 0.0014 0.0014
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0067 0.0046 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0183 0.0133 0.0132
Mycobacterium tuberculosis Probable monophosphatase 0.0012 0.0004 0.0083
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.0016 0.0007 0.0381
Plasmodium falciparum replication factor C subunit 1, putative 0.0012 0.0004 0.0082
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0097 0.0068 0.0068
Echinococcus multilocularis g protein coupled receptor 0.0025 0.0014 0.0016
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0002 0.0021
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0038 0.0024 0.0028
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0011 0.0225
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0057 0.0056
Echinococcus multilocularis thyroid hormone receptor alpha 0.0183 0.0133 0.0164
Brugia malayi beta-lactamase family protein 0.0043 0.0028 0.0027
Loa Loa (eye worm) glycogen phosphorylase 0.0219 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0008 0.0002 0.0016
Schistosoma mansoni hypothetical protein 0.0051 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0008 0.0001 0.0007
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.008 0.1845
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.004
Echinococcus multilocularis muscleblind protein 1 0.018 0.0131 0.0162
Brugia malayi Inositol monophosphatase family protein 0.0012 0.0004 0.0004
Brugia malayi SET domain containing protein 0.0013 0.0005 0.0004
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0008 0.0008
Giardia lamblia Kinase, PLK 0.0114 0.0082 0.0217
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0008 0.0008
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0576 0.0429 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0086 0.0086
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0012 0.0004 0.0076
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0085 0.0084
Echinococcus granulosus nibrin 0.0012 0.0004 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0183 0.0133 0.0132
Brugia malayi MH2 domain containing protein 0.001 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0019 0.0018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Brugia malayi conserved hypotetical protein 0.0086 0.006 0.006
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0012 0.0004 0.0076
Schistosoma mansoni intermediate filament proteins 0.0027 0.0015 0.0015
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0002 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0011 0.0225
Schistosoma mansoni voltage-gated potassium channel 0.002 0.001 0.001
Loa Loa (eye worm) beta-lactamase 0.0043 0.0028 0.0027
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0008 0.0002 0.0014
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Toxoplasma gondii subtilisin SUB11 0.0576 0.0429 1
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0018 0.0408
Mycobacterium ulcerans monophosphatase CysQ 0.0012 0.0004 0.0076
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Echinococcus granulosus protein arginine N methyltransferase 8 0.0069 0.0048 0.0046
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0017 0.0369
Brugia malayi cation channel family protein 0.0017 0.0008 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0025 0.0014 0.0014
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0012 0.0249
Schistosoma mansoni topbp1 0.0012 0.0004 0.0004
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0019 0.0423
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0004
Brugia malayi intermediate filament protein 0.0027 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0183 0.0133 0.0132
Schistosoma mansoni peptidase Clp (S14 family) 0.0081 0.0057 0.0057
Schistosoma mansoni smad1 5 8 and 0.001 0.0003 0.0003
Loa Loa (eye worm) helicase 0.0011 0.0004 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0004
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.008 0.1845
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0017 0.0008 0.0007
Entamoeba histolytica glycogen phosphorylase, putative 0.0095 0.0067 0.4119
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0576 0.0429 0.0428
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Onchocerca volvulus 0.0042 0.0027 0.0603
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0011 0.0225
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0002 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0014 0.0014
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0008 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0038 0.0061
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0576 0.0429 0.0703
Loa Loa (eye worm) subtilase 0.0576 0.0429 0.0428
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0038 0.0024 0.0527
Loa Loa (eye worm) hypothetical protein 0.0104 0.0074 0.0073
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0025 0.0014 0.0016
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0028 0.0637
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Echinococcus granulosus inositol monophosphatase 1 0.0114 0.0081 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0017 0.0008 0.0007
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0004 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0003 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0113 0.0112
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0004 0.0003
Onchocerca volvulus 0.0025 0.0014 0.0307
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0017 0.0369
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Onchocerca volvulus 0.0008 0.0002 0.0021
Brugia malayi RE15519p 0.0025 0.0014 0.0013
Onchocerca volvulus 0.0016 0.0008 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0576 0.0429 0.0703
Echinococcus multilocularis sodium leak channel non selective protein 0.0017 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0017 0.0366
Echinococcus multilocularis orexin receptor type 2 0.0025 0.0014 0.0016
Loa Loa (eye worm) DR-78 0.0086 0.006 0.006
Echinococcus granulosus Smad4 0.001 0.0003 0.0002
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0028 0.0637
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0019 0.0023
Brugia malayi MH1 domain containing protein 0.001 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0025 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0017 0.0016
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0017 0.0008 0.0156
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0001
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0113 0.0081 0.1854
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0017 0.0369
Leishmania major arginine N-methyltransferase-like protein 0.0067 0.0046 0.104
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0032 0.0032
Brugia malayi hypothetical protein 0.0161 0.0117 0.0116
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0012 0.0004 0.0003
Echinococcus multilocularis somatostatin receptor 0.0025 0.0014 0.0016
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0004 0.0003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0028 0.0027
Schistosoma mansoni hypothetical protein 0.0014 0.0006 0.0006
Brugia malayi putative neuropeptide receptor NPR1 0.0025 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus multilocularis cpg binding protein 0.0037 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Brugia malayi CCR4 0.0008 0.0002 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0183 0.0133 0.0132
Schistosoma mansoni flap endonuclease-1 0.0023 0.0013 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0097 0.0068 0.0067
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0021 0.0024
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 1.3293 1 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0081 0.0057 0.1303
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0001 0.0007
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0008 0.0173
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.8103 0.6093 1
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Brugia malayi sulfakinin receptor protein 0.0025 0.0014 0.0013
Brugia malayi hypothetical protein 0.0025 0.0014 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0014 0.0014
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0008 0.0007
Brugia malayi Thioredoxin reductase 0.0049 0.0032 0.0032
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Leishmania major RNA-editing complex protein MP100, putative 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Echinococcus multilocularis inositol monophosphatase 1 0.0114 0.0081 0.01
Trypanosoma brucei multidrug resistance protein E 0.0016 0.0007 0.0142
Loa Loa (eye worm) nuclear receptor NHR-67 0.0086 0.006 0.006
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0004 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0183 0.0133 0.0164
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0007 0.0149
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0025 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0183 0.0133 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0082 0.0132
Schistosoma mansoni hypothetical protein 0.0025 0.0014 0.0014
Echinococcus multilocularis expressed protein 0.004 0.0026 0.0031
Schistosoma mansoni multidrug resistance protein 0.0016 0.0007 0.0007
Brugia malayi G protein-coupled receptor F59B2.13 0.0025 0.0014 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0081 0.1873
Plasmodium falciparum DNase I-like protein, putative 0.0008 0.0002 0.0016
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0008 0.0001 0.0007
Loa Loa (eye worm) melatonin receptor type 1A 0.0025 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.0049 0.0032 0.0032
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0104 0.0074 0.1701
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0011 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0004 0.0005
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0172 0.0281
Leishmania major cytochrome p450-like protein 0.0029 0.0017 0.0371
Echinococcus multilocularis two pore calcium channel protein 1 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0025 0.0014 0.0013
Brugia malayi carbohydrate phosphorylase 0.0219 0.016 0.016
Echinococcus granulosus 7tm_1 domain containing protein 0.0025 0.0014 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0002 0.0001
Onchocerca volvulus Huntingtin homolog 0.0129 0.0093 0.2148
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0002 0.0014
Echinococcus granulosus neuropeptide receptor 0.0025 0.0014 0.0013
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0576 0.0429 0.0429
Echinococcus granulosus GPCR family 2 0.005 0.0033 0.0032
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0038 0.0024 0.0527
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0009 0.0009
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0008 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0043 0.0028 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0025 0.0014 0.0016
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0025 0.0558
Echinococcus granulosus cpg binding protein 0.0037 0.0023 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0183 0.0133 0.0132
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0006 0.0005
Onchocerca volvulus 0.0025 0.0014 0.0307
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0019 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.001 0.0014
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.0062 0.0062
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0183 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0028 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0031 0.003
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.021 0.026
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0008 0.0173
Mycobacterium leprae Probable lipase LipE 0.0043 0.0028 0.063
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0023
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0081 0.0132
Echinococcus multilocularis calcium activated potassium channel 0.0017 0.0008 0.0009
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0019 0.043
Plasmodium vivax subtilisin-like protease 2, putative 0.0576 0.0429 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0026 0.0024
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0016 0.0007 0.0142
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0025 0.0014 0.0016
Onchocerca volvulus 0.0043 0.0028 0.0637
Loa Loa (eye worm) G-protein coupled receptor 0.0025 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0004 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0025 0.0014 0.0014
Schistosoma mansoni amine GPCR 0.0025 0.0014 0.0014
Onchocerca volvulus 0.0086 0.006 0.1392
Schistosoma mansoni biogenic amine (5HT) receptor 0.0025 0.0014 0.0014
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0005 0.0004
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0019 0.0023
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0023
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0102 0.0072 0.1663
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0086 0.006 0.006
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.0082 0.5045
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0008 0.0002 0.0014
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0026 0.0579
Echinococcus granulosus multidrug resistance associated protein 4 0.0012 0.0005 0.0003
Brugia malayi Inositol monophosphatase family protein 0.0012 0.0004 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0002 0.0016
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0033 0.0032
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0005 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0025 0.0014 0.0016
Echinococcus multilocularis protein arginine methyltransferase 0.0069 0.0048 0.0058
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.008 0.1845
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0069 0.0048 0.109
Schistosoma mansoni carbonyl reductase 0.0008 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0051 0.0033 0.004
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0126 0.009 0.0089
Echinococcus multilocularis allatostatin A receptor 0.0025 0.0014 0.0016
Schistosoma mansoni hypothetical protein 0.0494 0.0367 0.0367
Brugia malayi hypothetical protein 0.0017 0.0008 0.0007
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0012 0.0004 0.04
Echinococcus multilocularis fmrfamide receptor 0.0025 0.0014 0.0016
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0008 0.0001 0.0007
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0038 0.0024 0.0534
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0319 0.0235 0.0291
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0007
Onchocerca volvulus 0.0017 0.0008 0.0164
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Echinococcus multilocularis neuroendocrine convertase 2 0.8376 0.6299 0.7837
Echinococcus granulosus c-Jun N-terminal kinases 0.0126 0.009 0.0089
Echinococcus multilocularis glycogen phosphorylase 0.0219 0.016 0.0198
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0001 0.0001
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0008 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.0025 0.0014 0.0016
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0005 0.0006
Toxoplasma gondii exonuclease III APE 0.004 0.0026 0.0579
Echinococcus granulosus voltage gated potassium channel 0.0025 0.0014 0.0013
Echinococcus granulosus 7TM GPCR rhodopsin 0.0025 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.005 0.0033 0.0033
Echinococcus multilocularis potassium large conductance calcium activated 0.0017 0.0008 0.0008
Brugia malayi multidrug resistance related protein 1 0.0016 0.0007 0.0006
Schistosoma mansoni multidrug resistance protein 0.0016 0.0007 0.0007
Schistosoma mansoni Smad4 0.001 0.0003 0.0003
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.0062 0.0076
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0576 0.0429 0.0428
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0166
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0002 0.0001
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0002 0.0021
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0034 0.0033
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0183 0.0133 0.0164
Leishmania major hypothetical protein, conserved 0.0008 0.0002 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.2609 0.1959 0.3213
Brugia malayi ion channel NompC 0.0017 0.0008 0.0007
Echinococcus granulosus Chromobox protein 3 0.0011 0.0004 0.0003
Brugia malayi olfactory channel protein osm-9 0.0017 0.0008 0.0007
Schistosoma mansoni hypothetical protein 0.0107 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0286 0.021 0.021
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.0002 0.0021
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0002 0.0016
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0319 0.0235 0.0291
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0011 0.0218
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0008 0.0008
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0004 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0183 0.0133 0.0132
Schistosoma mansoni hypothetical protein 0.0049 0.0032 0.0032
Schistosoma mansoni nocturnin 0.0008 0.0002 0.0002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0002 0.0016
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0104 0.0074 0.4574
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0008 0.0002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0076 0.0052 0.0052
Onchocerca volvulus 0.0235 0.0172 0.4001
Schistosoma mansoni nuclear receptor nhr-48 0.0086 0.006 0.006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0026 0.0579
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0004 0.0005
Schistosoma mansoni synaptojanin 0.0008 0.0002 0.0002
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0032 0.0032
Brugia malayi beta-lactamase family protein 0.0043 0.0028 0.0027
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0002 0.0008
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0008 0.0173

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 1.584893192 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.818382931 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 11.22018454 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
EC50 (binding) > 300 um PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Identify Inhibitors of Mex-5 Binding to TCR-2. (Class of assay: confirmatory) [Related pubchem assays: 1833 (Project Summary), 1832 (Primary HTS)] ChEMBL. No reference
EC50 (binding) > 300 um PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Identify Inhibitors of POS-1 Binding to mex-3-RNA. (Class of assay: confirmatory) [Related pubchem assays: 1833 (Project Summary), 1832 (Primary HTS)] ChEMBL. No reference
Potency (functional) = 0.1259 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 2.2387 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 2.2387 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.9093 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.0131 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.3808 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.6626 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.9811 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.4668 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.1735 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.7016 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3078 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.1995 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485342, AID485388] ChEMBL. No reference
Potency (functional) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 79.4328 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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