Detailed information for compound 69065

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 399.444 | Formula: C20H25N5O4
  • H donors: 4 H acceptors: 6 LogP: 1.33 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1OC(C(C1O)(C)O)n1cnc2c1ncnc2N[C@H](Cc1ccccc1)C
  • InChi: 1S/C20H25N5O4/c1-12(8-13-6-4-3-5-7-13)24-17-15-18(22-10-21-17)25(11-23-15)19-20(2,28)16(27)14(9-26)29-19/h3-7,10-12,14,16,19,26-28H,8-9H2,1-2H3,(H,21,22,24)/t12-,14?,16?,19?,20?/m1/s1
  • InChiKey: WJCRFGFGOJNWSD-HFZMXODFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0037 0.0068 0.0149
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0029 0.0048
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Leishmania major cathepsin L-like protease 0.0047 0.0103 0.0116
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Schistosoma mansoni hypothetical protein 0.0055 0.013 0.0161
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.035 0.0847
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0029 0.004 0.0066
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Brugia malayi Cathepsin L-like precursor 0.0047 0.0103 0.0128
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0066 0.0169
Brugia malayi Retinol dehydrogenase 12 0.0023 0.0019 0.0024
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0077 0.0198
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0106 0.0132
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Echinococcus granulosus prefoldin subunit 6 0.0069 0.0181 0.0438
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0071 0.0188 0.0178
Schistosoma mansoni neuropeptide F-like receptor 0.0042 0.0085 0.0105
Trypanosoma brucei calpain-like protein, putative 0.0086 0.0241 0.0302
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0341 0.0887
Schistosoma mansoni hypothetical protein 0.0048 0.0107 0.0133
Onchocerca volvulus 0.0042 0.0085 0.019
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0222 0.0722 0.0895
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0077 0.0185
Echinococcus multilocularis p2X purinoceptor 4 0.007 0.0183 0.0302
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0084 0.0235 0.0291
Echinococcus multilocularis RNA directed DNA polymerase 0.0039 0.0075 0.0124
Brugia malayi hypothetical protein 0.0086 0.0243 0.0301
Echinococcus granulosus membrane bound transcription factor site 1 0.0071 0.0188 0.0455
Loa Loa (eye worm) hypothetical protein 0.007 0.0184 0.0228
Onchocerca volvulus 0.0128 0.0392 0.0933
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0017 0.0028
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0152 0.0177
Trypanosoma brucei oligopeptidase b 0.0472 0.1608 0.202
Leishmania major DNA polymerase eta, putative 0.0039 0.0077 0.0083
Echinococcus multilocularis cysteine protease 0.0047 0.0103 0.017
Echinococcus multilocularis prolyl endopeptidase 0.1187 0.4138 0.6812
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0038 0.0099
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Brugia malayi nuclear hormone receptor 0.0023 0.0017 0.0021
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0228 0.0743 0.0921
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0376 0.1267 0.3061
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0019 0.0113
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0222 0.0722 0.0712
Onchocerca volvulus Sepiapterin reductase homolog 0.0023 0.0019 0.0031
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0019 0.0096
Echinococcus multilocularis neuropeptide receptor A26 0.0042 0.0085 0.0139
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0006 0.0015
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.086 0.2981 0.4908
Echinococcus granulosus tyrosine kinase 0.0022 0.0016 0.0039
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0006
Echinococcus multilocularis histone deacetylase 1 0.0352 0.1182 0.1946
Loa Loa (eye worm) endoprotease bli-4 0.0071 0.0188 0.0233
Onchocerca volvulus 0.0023 0.0019 0.0031
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0042 0.0085 0.0105
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0048 0.0107 0.026
Onchocerca volvulus 0.0042 0.0085 0.019
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0103 0.0631
Plasmodium falciparum plasmepsin IX 0.0394 0.1332 1
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0071 0.0188 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0188 0.0488
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0478 0.1629 0.4238
Brugia malayi G-protein coupled receptor 0.0042 0.0085 0.0105
Echinococcus granulosus cathepsin b 0.0311 0.1039 0.2511
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0047 0.0103 0.017
Leishmania major hypothetical protein, conserved 0.0134 0.041 0.0503
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Schistosoma mansoni glutamate receptor kainate 0.0079 0.0215 0.0267
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.009 0.0192
Loa Loa (eye worm) hypothetical protein 0.0128 0.0392 0.0486
Echinococcus multilocularis histone deacetylase 0.021 0.068 0.112
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Entamoeba histolytica P-glyco protein 6, putative 0.0036 0.0066 0.04
Brugia malayi nuclear receptor NHR-88 0.0023 0.0017 0.0021
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0071 0.0188 0.017
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0242 0.0792 0.1304
Echinococcus granulosus lamin dm0 0.0054 0.0128 0.031
Giardia lamblia Sirtuin type 2 0.0098 0.0286 0.1699
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Echinococcus multilocularis chromatin regulatory protein sir2 0.0478 0.1629 0.2681
Plasmodium vivax SET domain protein, putative 0.0064 0.0165 0.12
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus granulosus calpain 5 0.0089 0.0253 0.0611
Loa Loa (eye worm) hypothetical protein 0.0081 0.0225 0.0278
Onchocerca volvulus 0.0054 0.0128 0.0295
Plasmodium falciparum plasmepsin VII 0.007 0.0184 0.134
Loa Loa (eye worm) hypothetical protein 0.0222 0.0722 0.0895
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma brucei unspecified product 0.0027 0.0033 0.0041
Schistosoma mansoni multidrug resistance protein 0.0036 0.0066 0.0081
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Echinococcus multilocularis caspase 2 0.0128 0.0392 0.0645
Schistosoma mansoni hypothetical protein 0.0048 0.0105 0.0131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0023 0.0019 0.0051
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0101 0.0295 0.0485
Mycobacterium tuberculosis Conserved protein 0.0022 0.0015 0.0005
Loa Loa (eye worm) hypothetical protein 0.0267 0.0883 0.1095
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0077 0.0468
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.002
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.002
Onchocerca volvulus 0.0142 0.0439 0.1047
Schistosoma mansoni chromatin regulatory protein sir2 0.0478 0.1629 0.2019
Echinococcus multilocularis histone deacetylase 8 0.0126 0.0383 0.0631
Schistosoma mansoni histone deacetylase 1 2 3 0.0126 0.0383 0.0475
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0017 0.0027
Echinococcus multilocularis survival motor neuron protein 1 0.0267 0.0883 0.1454
Brugia malayi Cathepsin L-like precursor 0.0047 0.0103 0.0128
Giardia lamblia Cathepsin B precursor 0.0107 0.0317 0.1894
Echinococcus multilocularis p2X purinoceptor 4 0.007 0.0183 0.0302
Mycobacterium ulcerans dehydrogenase 0.0023 0.0019 0.0008
Brugia malayi Trypsin family protein 0.0048 0.0107 0.0133
Brugia malayi multidrug resistance protein 3 0.0036 0.0066 0.0081
Brugia malayi Thioredoxin reductase 0.004 0.0079 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Echinococcus granulosus GPCR family 2 0.0048 0.0105 0.0255
Brugia malayi neuropeptide F receptor 0.0042 0.0085 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0188 0.0488
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0222 0.0722 0.0712
Echinococcus granulosus p2X purinoceptor 4 0.007 0.0183 0.0443
Mycobacterium leprae Probable lipase LipE 0.0222 0.0722 0.0705
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0454 0.1544 0.1914
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Echinococcus granulosus hypothetical protein 0.0042 0.0085 0.0205
Loa Loa (eye worm) hypothetical protein 0.0222 0.0722 0.0895
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0077 0.0096
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0048 0.0107 0.0133
Brugia malayi calpain 5 0.0063 0.0161 0.02
Trichomonas vaginalis glucosylceramidase, putative 0.1103 0.3842 1
Echinococcus multilocularis cathepsin b 0.0311 0.1039 0.171
Echinococcus granulosus nmda type glutamate receptor 0.0184 0.0587 0.1418
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0106 0.0274
Echinococcus multilocularis geminin 0.0678 0.2336 0.3846
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0017 0.0021
Onchocerca volvulus 0.0048 0.0107 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Loa Loa (eye worm) hypothetical protein 0.0238 0.078 0.0967
Trypanosoma cruzi histone deacetylase, putative 0.021 0.068 0.0854
Onchocerca volvulus 0.0048 0.0107 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Schistosoma mansoni cpg binding protein 0.003 0.0044 0.0054
Toxoplasma gondii subtilisin SUB12 0.0108 0.0319 0.0747
Echinococcus multilocularis retinol dehydrogenase 11 0.0023 0.0019 0.0031
Echinococcus granulosus histone deacetylase 6 0.021 0.068 0.1644
Mycobacterium ulcerans oxidoreductase 0.0023 0.0019 0.0008
Echinococcus multilocularis cathepsin b 0.0311 0.1039 0.171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Schistosoma mansoni glutamate receptor NMDA 0.0255 0.0841 0.1043
Brugia malayi MH1 domain containing protein 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0128 0.0392 0.0486
Onchocerca volvulus 0.0055 0.013 0.03
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0006 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Plasmodium falciparum thioredoxin reductase 0.004 0.0079 0.0546
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0042 0.0085 0.0139
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0478 0.1629 0.2681
Mycobacterium tuberculosis Probable reductase 0.0091 0.026 0.0249
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0478 0.1629 1
Plasmodium vivax plasmepsin V, putative 0.007 0.0184 0.134
Trypanosoma brucei kinesin, putative 0.006 0.015 0.0187
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) PAN domain-containing protein 0.0037 0.0068 0.0084
Echinococcus multilocularis tissue type plasminogen activator 0.0081 0.0225 0.037
Echinococcus granulosus dna polymerase eta 0.0039 0.0077 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0047 0.0103 0.0268
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Echinococcus multilocularis prefoldin subunit 6 0.0069 0.0181 0.0299
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0035 0.0062 0.0077
Trypanosoma brucei PAB1-binding protein , putative 0.0134 0.041 0.0515
Loa Loa (eye worm) inositol-1 0.0114 0.0341 0.0423
Onchocerca volvulus 0.0042 0.0085 0.019
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0028 0.0073
Echinococcus multilocularis serotonin receptor 0.0042 0.0085 0.0139
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.009 0.0633
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0019 0.0008
Onchocerca volvulus 0.0042 0.0085 0.019
Plasmodium vivax vivapain-3 0.0029 0.0038 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0352 0.1181 0.3074
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0023 0.0019 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0317 0.0824
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0008
Schistosoma mansoni retinal dehydrogenase 0.0023 0.0019 0.0024
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Echinococcus granulosus cathepsin l1 0.0047 0.0103 0.025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.018
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0023 0.0019 0.0031
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0052 0.0127
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0006 0.0015
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0179 0.0571 0.0708
Loa Loa (eye worm) transcriptional regulator 0.0478 0.1629 0.2019
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.0023
Echinococcus multilocularis cathepsin L cysteine protease 0.0047 0.0103 0.017
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Loa Loa (eye worm) hypothetical protein 0.0084 0.0235 0.0291
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0017 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Leishmania major cytochrome p450-like protein 0.0023 0.0018 0.0009
Leishmania major calpain family cysteine protease-like protein 0.0026 0.0028 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0033 0.0041
Echinococcus granulosus sex peptide receptor 0.0042 0.0085 0.0205
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Trichomonas vaginalis penicillin-binding protein, putative 0.0222 0.0722 0.1879
Echinococcus granulosus receptor type guanylyl cyclase 0.0022 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni carbonic anhydrase-related 0.0084 0.0235 0.0291
Echinococcus granulosus muscleblind protein 0.0172 0.0547 0.1321
Brugia malayi MH2 domain containing protein 0.0478 0.1629 0.2019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0042 0.0085 0.0139
Schistosoma mansoni importin beta-1 0.0059 0.0145 0.018
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0042 0.0085 0.0139
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.0522 0.1784 0.2211
Loa Loa (eye worm) histone deacetylase 1 0.0352 0.1182 0.1465
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0152 0.0188
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0017 0.0021
Echinococcus granulosus g protein coupled receptor 0.0042 0.0085 0.0205
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0019 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0478 0.1629 0.2019
Onchocerca volvulus 0.0047 0.0103 0.0235
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0018 0.0022
Echinococcus granulosus biogenic amine 5HT receptor 0.0042 0.0085 0.0205
Brugia malayi ERG2 and Sigma1 receptor like protein 0.2266 0.7956 0.9862
Echinococcus granulosus histone deacetylase 0.021 0.068 0.1644
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0241 0.0302
Brugia malayi MH2 domain containing protein 0.0033 0.0052 0.0065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 0.1039 0.1288
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0107 0.0133
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0222 0.0722 0.0895
Onchocerca volvulus 0.0037 0.0068 0.0149
Toxoplasma gondii histone deacetylase SIR2-like 0.0098 0.0286 0.0666
Brugia malayi dehydrogenases, short chain protein 9 0.0023 0.0019 0.0024
Loa Loa (eye worm) sirtuin 4 0.0098 0.0286 0.0354
Plasmodium vivax histone deacetylase 2, putative 0.021 0.068 0.5083
Echinococcus granulosus g protein coupled receptor 0.0042 0.0085 0.0205
Toxoplasma gondii histone deacetylase HDAC2 0.0352 0.1182 0.2838
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0029 0.004 0.0066
Onchocerca volvulus 0.0042 0.0085 0.019
Echinococcus granulosus carbonic anhydrase 0.0084 0.0235 0.0568
Echinococcus granulosus neuropeptide receptor 0.0042 0.0085 0.0205
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.0928 0.115
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0124 0.0378 0.0462
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0238 0.078 0.0967
Schistosoma mansoni lipoxygenase 0.0082 0.0226 0.028
Onchocerca volvulus 0.0042 0.0085 0.019
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0018 0.0023
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0454 0.1544 0.3732
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0066 0.0159
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Mycobacterium ulcerans dehydrogenase/reductase 0.0023 0.0019 0.0008
Brugia malayi Receptor family ligand binding region containing protein 0.0035 0.0062 0.0077
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.0271 0.0336
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0023 0.0019 0.0113
Echinococcus multilocularis multidrug resistance protein 1 0.0036 0.0066 0.0108
Echinococcus multilocularis glutamate receptor NMDA 0.0154 0.0484 0.0796
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0011 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.0023
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0152 0.0367
Schistosoma mansoni gabp alpha 0.0072 0.0193 0.0239
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Echinococcus granulosus Dipeptidyl peptidase 9 0.0124 0.0378 0.0913
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0124 0.0378 0.0474
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0141
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0472 0.1608 0.1599
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0098 0.0286 0.047
Echinococcus multilocularis neuropeptide receptor 0.0042 0.0085 0.0139
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.026 0.0241
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0017 0.0021
Onchocerca volvulus 0.0048 0.0107 0.0245
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0098 0.0286 0.0742
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0098 0.0286 0.0691
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) glutamate receptor 1 0.0079 0.0215 0.0267
Entamoeba histolytica cysteine proteinase 1, putative 0.0029 0.0038 0.0232
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Schistosoma mansoni smad 0.0033 0.0052 0.0065
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0066 0.0169
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 0.1039 0.1288
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0222 0.0722 0.0705
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0114 0.0341 0.0801
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0098 0.0286 0.0358
Trypanosoma brucei calpain, putative 0.0026 0.0028 0.0035
Onchocerca volvulus 0.0042 0.0085 0.019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Giardia lamblia Histone deacetylase 0.0352 0.1182 0.724
Brugia malayi beta-lactamase 0.0222 0.0722 0.0895
Brugia malayi Cathepsin L-like precursor 0.0047 0.0103 0.0128
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0023 0.0019 0.0024
Echinococcus multilocularis RUN 0.002 0.0006 0.001
Loa Loa (eye worm) calpain 5 0.006 0.015 0.0185
Schistosoma mansoni smdr2 0.0036 0.0066 0.0081
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0103 0.0129
Plasmodium falciparum ataxin-2 like protein, putative 0.0134 0.041 0.3048
Echinococcus granulosus inhibitor of apoptosis protein 0.0454 0.1544 0.3732
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0029 0.004 0.0097
Plasmodium vivax vivapain-2 0.0047 0.0103 0.0733
Plasmodium vivax aspartyl proteinase, putative 0.007 0.0184 0.134
Trichomonas vaginalis calpain, putative 0.0026 0.0028 0.0073
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0124 0.0378 0.0474
Toxoplasma gondii oxidoreductase, putative 0.0023 0.0019 0.002
Trypanosoma brucei prefoldin subunit, putative 0.0069 0.0181 0.0227
Schistosoma mansoni hypothetical protein 0.0081 0.0225 0.0278
Plasmodium vivax aspartyl protease, putative 0.0394 0.1332 1
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.028 0.0928 0.115
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0098 0.0286 0.0358
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0107 0.0317 0.0398
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0472 0.1608 0.202
Echinococcus multilocularis muscleblind protein 1 0.0172 0.0547 0.09
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0315 0.1053 0.2546
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0066 0.0169
Leishmania major 3-keto-dihydrosphingosine reductase 0.0023 0.0019 0.001
Echinococcus granulosus cpg binding protein 0.003 0.0044 0.0105
Schistosoma mansoni ap endonuclease 0.0021 0.0011 0.0013
Echinococcus granulosus hypothetical protein 0.0023 0.0019 0.0046
Toxoplasma gondii subtilisin SUB2 0.0071 0.0188 0.043
Echinococcus multilocularis g protein coupled receptor 0.0042 0.0085 0.0139
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0023 0.0019 0.0096
Echinococcus granulosus survival motor neuron protein 1 0.0267 0.0883 0.2135
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Onchocerca volvulus 0.0222 0.0722 0.1733
Brugia malayi prolyl oligopeptidase family protein 0.0124 0.0378 0.0468
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0113 0.0335 0.0552
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0456 0.0565
Trypanosoma cruzi histone deacetylase, putative 0.0126 0.0383 0.0481
Brugia malayi transcriptional regulator, Sir2 family protein 0.0098 0.0286 0.0354
Giardia lamblia Short-chain dehydrogenase, putative 0.0023 0.0019 0.0051
Schistosoma mansoni chromatin regulatory protein sir2 0.0315 0.1053 0.1306
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis histone deacetylase, putative 0.0352 0.1182 0.3076
Onchocerca volvulus 0.0042 0.0085 0.019
Schistosoma mansoni histone deacetylase 0.0352 0.1182 0.1465
Echinococcus granulosus G protein coupled receptor 139 0.0042 0.0085 0.0205
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0042 0.0085 0.0205
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni neuropeptide receptor 0.0042 0.0085 0.0105
Mycobacterium leprae Possible secreted protease 0.0071 0.0188 0.017
Brugia malayi Pre-SET motif family protein 0.0446 0.1515 0.1877
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0023 0.0019 0.0113
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.0271 0.0446
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0038 0.0232
Echinococcus granulosus acylamino acid releasing enzyme 0.0124 0.0378 0.0913
Trypanosoma brucei prolyl oligopeptidase, putative 0.0472 0.1608 0.202
Schistosoma mansoni P2X receptor subunit 0.007 0.0183 0.0227
Loa Loa (eye worm) G-protein coupled receptor 0.0042 0.0085 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Entamoeba histolytica hypothetical protein 0.0148 0.0461 0.283
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0165 0.0399
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Schistosoma mansoni histone deacetylase hda2 0.0126 0.0383 0.0475
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0059 0.0073
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0071 0.0188 0.0233
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.0296 0.0285
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0017 0.0042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0028 0.0073
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0039 0.0075 0.0124
Schistosoma mansoni myosin xvIII 0.0042 0.0085 0.0105
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0023 0.0019 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Toxoplasma gondii microneme protein MIC17B 0.0037 0.0068 0.0138
Leishmania major importin beta-1 subunit, putative 0.0048 0.0106 0.012
Trichomonas vaginalis taga, putative 0.0036 0.0066 0.0169
Echinococcus multilocularis Furin 1 0.0071 0.0188 0.031
Echinococcus granulosus orexin receptor type 2 0.0042 0.0085 0.0205
Entamoeba histolytica protein kinase, putative 0.006 0.015 0.092
Brugia malayi MH1 domain containing protein 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0042 0.0085 0.019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0159 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0378 0.0982
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Mycobacterium tuberculosis Possible oxidoreductase 0.0023 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Brugia malayi Fli-1 protein 0.022 0.0714 0.0885
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Brugia malayi mbt repeat family protein 0.0094 0.0271 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0017 0.0021
Schistosoma mansoni caspase-7 (C14 family) 0.0128 0.0392 0.0486
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0042 0.0085 0.0205
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0128 0.0159
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0017 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Echinococcus granulosus transmembrane protease serine 3 0.0048 0.0107 0.026
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Loa Loa (eye worm) pigment dispersing factor receptor c 0.015 0.0469 0.0582
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0098 0.0286 0.0691
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Mycobacterium tuberculosis Conserved protein 0.0222 0.0722 0.0712
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0165 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Loa Loa (eye worm) glutamate receptor 2 0.0079 0.0215 0.0267
Schistosoma mansoni chromatin regulatory protein sir2 0.0478 0.1629 0.2019
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0017 0.0021
Onchocerca volvulus 0.0507 0.1732 0.4177
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0023 0.0019 0.0008
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.009 0.0113
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0023 0.0019 0.0008
Brugia malayi NAD-dependent deacetylase SIRT1 0.0315 0.1053 0.1306
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0018 0.0023
Leishmania major hypothetical protein, conserved 0.0023 0.0019 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0071 0.0188 0.0178
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1417 0.4954 0.4948
Trichomonas vaginalis glucosylceramidase, putative 0.1103 0.3842 1
Mycobacterium ulcerans oxidoreductase 0.0023 0.0019 0.0008
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0023 0.0019 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Mycobacterium ulcerans histidinol dehydrogenase 0.2843 1 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0125 0.0154
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0136 0.0304
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0193 0.0239
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0145 0.0325
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0042 0.0085 0.0105
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Loa Loa (eye worm) RGC/RGC protein kinase 0.0022 0.0016 0.002
Onchocerca volvulus 0.0023 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0018 0.0022
Echinococcus multilocularis beta LACTamase domain containing family member 0.0222 0.0722 0.1189
Schistosoma mansoni histone deacetylase 0.0352 0.1182 0.1465
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0038 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0042 0.0085 0.0105
Echinococcus multilocularis g-protein coupled receptor 0.0042 0.0085 0.0139
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0352 0.1182 0.3076
Echinococcus multilocularis histone acetyltransferase MYST2 0.0107 0.0317 0.0522
Plasmodium falciparum subtilisin-like protease 2 0.0071 0.0188 0.1373
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.029
Plasmodium vivax glutathione reductase, putative 0.004 0.0079 0.0546
Trichomonas vaginalis glucosylceramidase, putative 0.1103 0.3842 1
Leishmania major short chain dehydrogenase, putative 0.0023 0.0019 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Brugia malayi Trypsin-like protease protein 5 0.0048 0.0107 0.0133
Loa Loa (eye worm) prolyl oligopeptidase 0.0124 0.0378 0.0468
Leishmania major hypothetical protein, conserved 0.0023 0.0019 0.001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Mycobacterium ulcerans hypothetical protein 0.0222 0.0722 0.0712
Brugia malayi Importin beta-1 subunit 0.0059 0.0145 0.018
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0311 0.1039 0.1288
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0023 0.0019 0.0023
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0147 0.0456 0.1102
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0165 0.0374
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0073
Entamoeba histolytica calpain family cysteine protease, putative 0.0026 0.0028 0.0171
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Entamoeba histolytica short chain dehydrogenase family protein 0.0023 0.0019 0.0113
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0042 0.0085 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0017 0.0021
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Schistosoma mansoni tyrosine kinase 0.0022 0.0016 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Echinococcus granulosus histone deacetylase 6 0.021 0.068 0.1644
Schistosoma mansoni hypothetical protein 0.0405 0.1371 0.1699
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0107 0.0133
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0114 0.0341 0.0331
Trichomonas vaginalis abcb9, putative 0.0036 0.0066 0.0169
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0145 0.0182
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Plasmodium vivax hypothetical protein, conserved 0.0222 0.0722 0.5402
Echinococcus multilocularis NMDA receptor 0.0029 0.004 0.0066
Echinococcus multilocularis glutamate receptor 2 0.0101 0.0295 0.0485
Echinococcus multilocularis g protein coupled receptor 0.0042 0.0085 0.0139
Trypanosoma brucei Calpain-like protein 1.1 0.0026 0.0028 0.0035
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0052 0.0127
Toxoplasma gondii kringle domain-containing protein 0.0081 0.0225 0.0518
Schistosoma mansoni P2X receptor subunit 0.007 0.0183 0.0227
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0023 0.0019 0.0048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0222 0.0722 0.0895
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0023 0.0019 0.0023
Echinococcus granulosus Mastin 0.0048 0.0107 0.026
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0023 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0084 0.0235 0.0291
Toxoplasma gondii PAN/Apple domain-containing protein 0.0037 0.0068 0.0138
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0023 0.0019 0.0031
Schistosoma mansoni ran 0.0043 0.009 0.0112
Loa Loa (eye worm) PAN domain-containing protein 0.0037 0.0068 0.0084
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Echinococcus granulosus RUN 0.002 0.0006 0.0015
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0478 0.1629 0.2046
Giardia lamblia Cathepsin B precursor 0.0107 0.0317 0.1894
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0036 0.0066 0.5
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0478 0.1629 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0042 0.0085 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0241 0.0302
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0098 0.0286 0.047
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0028 0.0035
Echinococcus multilocularis hypothetical protein 0.0086 0.0241 0.0397
Plasmodium vivax histone deacetylase, putative 0.0126 0.0383 0.2845
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0098 0.0286 0.0742
Toxoplasma gondii hypothetical protein 0.0084 0.0235 0.0543
Trichomonas vaginalis glucosylceramidase, putative 0.1103 0.3842 1
Schistosoma mansoni tyrosine kinase 0.0022 0.0016 0.002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0017 0.0021
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0017 0.0042
Schistosoma mansoni hypothetical protein 0.006 0.0149 0.0185
Leishmania major hypothetical protein, conserved 0.0081 0.0225 0.0269
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Brugia malayi hypothetical protein 0.0134 0.041 0.0509
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0017 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.1103 0.3842 1
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0361 0.1216 0.1508
Brugia malayi metabotropic glutamate receptor type 2 0.0054 0.0127 0.0157
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0242 0.0792 0.1914
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0071 0.0188 0.0236
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.006 0.0149 0.0246
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0011 0.0027
Brugia malayi hypothetical protein 0.0128 0.0392 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0038 0.0099
Brugia malayi G protein-coupled receptor F59B2.13 0.0042 0.0085 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0038 0.0232
Echinococcus multilocularis GPCR, family 2 0.0048 0.0105 0.0174
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0028 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0033 0.0041
Leishmania major histone deacetylase, putative 0.0352 0.1182 0.1474
Echinococcus granulosus calpain A 0.0242 0.0793 0.1916
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0152 0.0188
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0103 0.0631
Plasmodium falciparum plasmepsin I 0.0147 0.0456 0.3392
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Giardia lamblia Cathepsin B precursor 0.0107 0.0317 0.1894
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Plasmodium falciparum subtilisin-like protease 1 0.0071 0.0188 0.1373
Echinococcus multilocularis snurportin 1 0.0627 0.2158 0.3552
Brugia malayi AKH receptor 0.0042 0.0085 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Echinococcus multilocularis transmembrane protease serine 3 0.0048 0.0107 0.0177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0036
Brugia malayi Trypsin family protein 0.0238 0.078 0.0967
Schistosoma mansoni glutamate receptor AMPA 0.0079 0.0215 0.0267
Echinococcus granulosus allatostatin A receptor 0.0042 0.0085 0.0205
Echinococcus granulosus RNA directed DNA polymerase 0.0039 0.0075 0.0182
Plasmodium vivax unspecified product 0.0029 0.0038 0.0243
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0052 0.0065
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1187 0.4138 0.5129
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.1371 0.2256
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0297 0.0988 0.2389
Onchocerca volvulus 0.0023 0.0019 0.0031
Loa Loa (eye worm) subtilase 0.2297 0.8067 1
Echinococcus multilocularis glutamate receptor 2 0.0072 0.0192 0.0315
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0071 0.0188 0.0236
Onchocerca volvulus Histone deacetylase 10 homolog 0.0126 0.0383 0.0913
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0084 0.0234 0.029
Echinococcus multilocularis carbonic anhydrase II 0.0179 0.0571 0.094
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0472 0.1608 0.202
Brugia malayi hypothetical protein 0.0522 0.1784 0.2211
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0315 0.1053 0.2741
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0124 0.0378 0.0889
Echinococcus multilocularis neuroendocrine convertase 2 0.0071 0.0188 0.031
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0128 0.0159
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0341 0.0887
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.0928 0.115
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0017 0.0027
Echinococcus multilocularis carbonic anhydrase 0.0084 0.0235 0.0387
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0023 0.0019 0.0008
Brugia malayi Serotonin receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0035 0.0062 0.0077
Schistosoma mansoni histone deacetylase 4 5 0.021 0.068 0.0843
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Schistosoma mansoni opsin-like receptor 0.0042 0.0085 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0023 0.0019 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.0153 0.048 0.0602
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trypanosoma brucei unspecified product 0.0027 0.0033 0.0041
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0098 0.0286 0.0742
Brugia malayi prolyl oligopeptidase family protein 0.0124 0.0378 0.0468
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0124 0.0378 0.0468
Mycobacterium tuberculosis Probable hydrolase 0.0222 0.0722 0.0712
Onchocerca volvulus 0.0023 0.0019 0.0031
Entamoeba histolytica hypothetical protein 0.0148 0.0461 0.283
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Schistosoma mansoni calpain-7 (C02 family) 0.0092 0.0262 0.0325
Onchocerca volvulus Prolyl endopeptidase homolog 0.1187 0.4138 1
Brugia malayi GnHR receptor homolog 0.0042 0.0085 0.0105
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0066 0.0169
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Brugia malayi Cathepsin L-like precursor 0.0047 0.0103 0.0128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Leishmania major calpain protease-like protein 0.0026 0.0028 0.0022
Trichomonas vaginalis histone deacetylase, putative 0.0352 0.1182 0.3076
Brugia malayi Trypsin family protein 0.0048 0.0107 0.0133
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0066 0.0169
Trichomonas vaginalis ran, putative 0.0043 0.009 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0105
Leishmania major GTP-binding protein, putative 0.0043 0.009 0.01
Echinococcus multilocularis allatostatin A receptor 0.0042 0.0085 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0165 0.0205
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0179 0.0571 0.0708
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Onchocerca volvulus 0.0023 0.0019 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0084 0.0235 0.0291
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Echinococcus granulosus peptide allatostatin:somatostatin 0.0042 0.0085 0.0205
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Entamoeba histolytica hypothetical protein 0.0148 0.0461 0.283
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Trypanosoma brucei histone deacetylase 3 0.021 0.068 0.0854
Loa Loa (eye worm) PAN domain-containing protein 0.0037 0.0068 0.0084
Schistosoma mansoni glutamate receptor NMDA 0.0187 0.0598 0.0741
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Plasmodium vivax multidrug resistance protein 1, putative 0.0036 0.0066 0.0448
Echinococcus granulosus biogenic amine 5HT receptor 0.0042 0.0085 0.0205
Echinococcus granulosus importin subunit beta 1 0.0059 0.0145 0.0351
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0018 0.0008
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0124 0.0378 0.0474
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0029 0.004 0.0097
Echinococcus granulosus histone deacetylase 6 0.021 0.068 0.1644
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0052 0.0065
Brugia malayi dehydrogenases, short chain protein 2 0.0023 0.0019 0.0024
Echinococcus multilocularis dna polymerase eta 0.0039 0.0077 0.0126
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.009 0.0491
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Brugia malayi Cathepsin L-like precursor 0.0034 0.0059 0.0073
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0066 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.0023
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0017 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0017 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.0042 0.0085 0.0205
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Mycobacterium ulcerans hypothetical protein 0.0048 0.0107 0.0097
Schistosoma mansoni chromatin regulatory protein sir2 0.0098 0.0286 0.0354
Entamoeba histolytica P-glycoprotein 5, putative 0.0036 0.0066 0.04
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Echinococcus granulosus g-protein coupled receptor 0.0042 0.0085 0.0205
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0071 0.0188 0.0236
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0478 0.1629 0.3936
Echinococcus granulosus glutamate receptor 2 0.0072 0.0192 0.0463
Schistosoma mansoni hypothetical protein 0.0048 0.0105 0.0131
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0042 0.0085 0.0205
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0105 0.0255
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0071 0.0188 0.0233
Schistosoma mansoni hypothetical protein 0.0148 0.0461 0.0572
Trypanosoma brucei calpain-like protein, putative 0.0086 0.0241 0.0302
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0124 0.0378 0.0622
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.0296 0.0277
Loa Loa (eye worm) hypothetical protein 0.0107 0.0317 0.0393
Plasmodium falciparum importin beta, putative 0.0059 0.0145 0.1048
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0047 0.0103 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Schistosoma mansoni amine GPCR 0.0042 0.0085 0.0105
Schistosoma mansoni lipoxygenase 0.0117 0.035 0.0434
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Plasmodium vivax aspartyl protease, putative 0.007 0.0184 0.134
Schistosoma mansoni coup transcription factor 0.0023 0.0017 0.0021
Onchocerca volvulus 0.0094 0.0271 0.064
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0193 0.0467
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0023 0.0019 0.0048
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0023 0.0019 0.0024
Echinococcus multilocularis calpain 5 0.0089 0.0253 0.0416
Toxoplasma gondii microneme protein MIC17C 0.0037 0.0068 0.0138
Schistosoma mansoni multidrug resistance protein 0.0036 0.0066 0.0081
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0315 0.1053 0.6445
Schistosoma mansoni neuropeptide receptor 0.0042 0.0085 0.0105
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0066 0.0108
Schistosoma mansoni cathepsin F (C01 family) 0.0047 0.0103 0.0128
Mycobacterium tuberculosis Probable dehydrogenase 0.0023 0.0019 0.0008
Brugia malayi hypothetical protein 0.007 0.0184 0.0228
Toxoplasma gondii oxidoreductase, putative 0.0023 0.0019 0.002
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.028 0.0928 0.1527
Trichomonas vaginalis histone deacetylase, putative 0.0352 0.1182 0.3076
Loa Loa (eye worm) TYRA-2 protein 0.0042 0.0085 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0023 0.0019 0.0031
Trypanosoma cruzi short chain dehydrogenase, putative 0.0023 0.0019 0.0023
Toxoplasma gondii histone deacetylase SIR2 0.0098 0.0286 0.0666
Brugia malayi putative neuropeptide receptor 0.0042 0.0085 0.0105
Brugia malayi hypothetical protein 0.007 0.0184 0.0228
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi cysteine protease, putative 0.0029 0.0038 0.0048
Echinococcus granulosus chromatin regulatory protein sir2 0.0478 0.1629 0.3936
Plasmodium falciparum prefoldin subunit 6, putative 0.0069 0.0181 0.1321
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0071 0.0188 0.0236
Schistosoma mansoni glutamate receptor AMPA 0.0079 0.0215 0.0267
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Mycobacterium ulcerans ketoacyl reductase 0.0023 0.0019 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0181 0.0471
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0047 0.0103 0.0128
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0027 0.0065
Plasmodium vivax vivapain-1 0.0029 0.0038 0.0243
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Toxoplasma gondii microneme protein MIC17A 0.0037 0.0068 0.0138
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0101 0.0295 0.0712
Trichomonas vaginalis histone deacetylase, putative 0.0352 0.1182 0.3076
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0036 0.0066 0.0081
Echinococcus granulosus tm gpcr rhodopsin 0.0548 0.1877 0.4537
Onchocerca volvulus 0.0042 0.0085 0.019
Schistosoma mansoni protein kinase 0.0022 0.0016 0.002
Schistosoma mansoni loxhd1 0.002 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.2266 0.7956 0.9862
Loa Loa (eye worm) dehydrogenase 0.0023 0.0019 0.0024
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0017 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0165 0.0205
Loa Loa (eye worm) hypothetical protein 0.0062 0.0156 0.0193
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0454 0.1544 0.1914
Echinococcus multilocularis g protein coupled receptor 0.0042 0.0085 0.0139
Trypanosoma brucei trypanothione reductase 0.004 0.0079 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0098 0.0286 0.2108
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Brugia malayi beta-lactamase family protein 0.0222 0.0722 0.0895
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Brugia malayi ecdysteroid receptor 0.0023 0.0017 0.0021
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0023 0.0019 0.0023
Toxoplasma gondii PAN domain-containing protein 0.0037 0.0068 0.0138
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.008 0.0132
Schistosoma mansoni furin-1 (S08 family) 0.0071 0.0188 0.0233
Schistosoma mansoni histamine h1 receptor 0.0042 0.0085 0.0105
Trypanosoma brucei Calpain-like protein 1.2 0.0026 0.0028 0.0035
Trypanosoma cruzi major cysteine proteinase, putative 0.0122 0.037 0.0465
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0472 0.1608 0.1592
Leishmania major short chain dehydrogenase/reductase, putative 0.0023 0.0019 0.001
Echinococcus multilocularis multidrug resistance protein 1 0.0025 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Loa Loa (eye worm) hypothetical protein 0.0128 0.0392 0.0486
Schistosoma mansoni calpain-7 (C02 family) 0.0092 0.0262 0.0325
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0042 0.0085 0.0105
Trypanosoma cruzi cruzipain precursor, putative 0.0153 0.048 0.0602
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.0023
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0189 0.0234
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0042 0.0085 0.0139
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0029 0.004 0.0097
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0042 0.0085 0.0105
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0079 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.0302
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0023 0.0019 0.0008
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.009 0.0148
Echinococcus granulosus dna polymerase kappa 0.0039 0.0077 0.0185
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.008 0.0194
Leishmania major cathepsin L-like protease 0.0047 0.0103 0.0116
Toxoplasma gondii PAN domain-containing protein 0.0037 0.0068 0.0138
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0124 0.0378 0.0468
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0047 0.0103 0.017
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi cysteine proteinase, putative 0.0029 0.0038 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.028 0.0928 0.2242
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Onchocerca volvulus 0.0023 0.0019 0.0031
Toxoplasma gondii PAN domain-containing protein 0.0344 0.1155 0.2773
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0028 0.0035
Trypanosoma brucei unspecified product 0.0039 0.0077 0.0096
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0179 0.0571 0.0708
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0105
Onchocerca volvulus 0.0042 0.0085 0.019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Onchocerca volvulus Cathepsin L homolog 0.0047 0.0103 0.0235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0071 0.0188 0.0178
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0071 0.0188 0.0178
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.026 0.0249
Mycobacterium tuberculosis Probable esterase LipL 0.0222 0.0722 0.0712
Echinococcus multilocularis muscleblind protein 0.0172 0.0547 0.09
Entamoeba histolytica P-glycoprotein-2 0.0036 0.0066 0.04
Onchocerca volvulus 0.0042 0.0085 0.019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.002
Schistosoma mansoni opsin-like receptor 0.0042 0.0085 0.0105
Entamoeba histolytica cysteine proteinase 2 0.0029 0.0038 0.0232
Leishmania major pteridine reductase 1 0.0023 0.0019 0.001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.015 0.0469 0.0582
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0233
Loa Loa (eye worm) hypothetical protein 0.0048 0.0105 0.0131
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0059 0.0359
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Brugia malayi sulfakinin receptor protein 0.0042 0.0085 0.0105
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0077 0.0066
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.0066 0.0169
Trypanosoma brucei cysteine peptidase, putative 0.0026 0.0028 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Leishmania major extracellular receptor, putative 0.0022 0.0016 0.0007
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Leishmania major hypothetical protein, conserved 0.0023 0.0019 0.001
Loa Loa (eye worm) cathepsin B 0.0107 0.0317 0.0393
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Schistosoma mansoni smad1 5 8 and 0.0033 0.0052 0.0065
Entamoeba histolytica prolyl oligopeptidase family protein 0.0124 0.0378 0.2317
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0145 0.0239
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Onchocerca volvulus 0.0454 0.1544 0.3722
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Trypanosoma brucei subtilisin peptidase 0.0071 0.0188 0.0236
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0035 0.0062 0.0077
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Brugia malayi Dopamine receptor protein 1 0.0042 0.0085 0.0105
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0311 0.1039 0.1305
Trypanosoma cruzi hypothetical protein, conserved 0.0222 0.0722 0.0907
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0023 0.0019 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Brugia malayi Cytochrome P450 family protein 0.0023 0.0018 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Loa Loa (eye worm) hypothetical protein 0.1187 0.4138 0.5129
Brugia malayi Muscleblind-like protein 0.0172 0.0547 0.0677
Loa Loa (eye worm) calpain 0.0086 0.0241 0.0299
Schistosoma mansoni site-1 peptidase (S08 family) 0.0071 0.0188 0.0233
Giardia lamblia Hypothetical protein 0.0069 0.0181 0.1054
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0042 0.0085 0.0105
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0042 0.0085 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0018 0.0023
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0036 0.0066 0.0169
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0148 0.0461 0.1115
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0098 0.0286 0.1752
Echinococcus granulosus cathepsin L cysteine protease 0.0029 0.0038 0.0093
Brugia malayi Receptor family ligand binding region containing protein 0.0022 0.0016 0.002
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0098 0.0286 0.0346
Echinococcus granulosus histone deacetylase 1 0.0352 0.1182 0.2857
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0023 0.0019 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0042 0.0085 0.0105
Echinococcus granulosus calpain 0.0086 0.0241 0.0582
Trypanosoma brucei calpain-like protein, putative 0.0086 0.0241 0.0302
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0017 0.0021
Brugia malayi mbt repeat family protein 0.0094 0.0271 0.0336
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0036 0.0066 0.0133
Brugia malayi RNA, U transporter 1 0.0167 0.0529 0.0655
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0378 0.0474
Schistosoma mansoni hypothetical protein 0.0084 0.0235 0.0291
Brugia malayi Doublecortin family protein 0.002 0.0006 0.0008
Plasmodium falciparum peptidase, putative 0.0124 0.0378 0.2802
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0023 0.0019 0.0008
Leishmania major cathepsin L-like protease 0.0153 0.048 0.059
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trypanosoma brucei histone deacetylase, putative 0.021 0.068 0.0854
Echinococcus multilocularis apoptotic protease activating factor 1 0.0128 0.0392 0.0645
Plasmodium falciparum plasmepsin V 0.007 0.0184 0.134
Leishmania major hypothetical protein, conserved 0.0023 0.0019 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Echinococcus granulosus carbonic anhydrase 0.0084 0.0235 0.0568
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0152 0.0341
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Onchocerca volvulus Deterin homolog 0.0454 0.1544 0.3722
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0017 0.0021
Schistosoma mansoni hypothetical protein 0.0048 0.0107 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.009 0.0112
Loa Loa (eye worm) hypothetical protein 0.0222 0.0722 0.0895
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0008
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0029 0.0071
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0188 0.0488
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0042 0.0085 0.0139
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0114 0.0341 1
Echinococcus multilocularis programmed cell death protein 0.0018 0.0001 0.0001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0098 0.0286 0.0742
Loa Loa (eye worm) hypothetical protein 0.0228 0.0743 0.0921
Schistosoma mansoni cpg binding protein 0.0028 0.0038 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0763 0.2637 0.6864
Echinococcus multilocularis calpain 0.0086 0.0241 0.0397
Plasmodium vivax subtilisin-like serine protease, putative 0.0071 0.0188 0.1373
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni survival motor neuron protein 0.0055 0.013 0.0161
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0048 0.0107 0.0177
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0047 0.0103 0.0733
Onchocerca volvulus Cathepsin F homolog 0.0047 0.0103 0.0235
Plasmodium falciparum plasmepsin VI 0.0147 0.0456 0.3392
Echinococcus granulosus lamin 0.0054 0.0128 0.031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.0302
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0124 0.0378 0.0913
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0102 0.0299 0.0288
Echinococcus multilocularis steroid dehydrogenase 0.0023 0.0019 0.0031
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0023 0.0019 0.0023
Plasmodium falciparum histone deacetylase, putative 0.021 0.068 0.5083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0241 0.0302
Brugia malayi cathepsin B-like cysteine proteinase 0.0311 0.1039 0.1288
Onchocerca volvulus 0.0081 0.0225 0.0528
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0222 0.0722 0.1879
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0098 0.0286 0.0742
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0052 0.0065
Brugia malayi MH1 domain containing protein 0.0033 0.0052 0.0065
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0081 0.0225 0.1647
Echinococcus granulosus steroid dehydrogenase 0.0023 0.0019 0.0046
Mycobacterium ulcerans ketoacyl reductase 0.0023 0.0019 0.0008
Onchocerca volvulus 0.0047 0.0103 0.0235
Echinococcus multilocularis glutamate receptor 2 0.0079 0.0215 0.0354
Toxoplasma gondii prolyl endopeptidase 0.1187 0.4138 1
Trypanosoma brucei histone deacetylase 1 0.0352 0.1182 0.1485
Plasmodium falciparum cysteine repeat modular protein 1 0.0081 0.0225 0.1647
Echinococcus granulosus p2X purinoceptor 4 0.007 0.0183 0.0443
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0105 0.0174
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0077 0.0095
Echinococcus granulosus metabotropic glutamate receptor 5 0.0113 0.0335 0.0811
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0048 0.0107 0.0133
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Trypanosoma brucei hypothetical protein 0.0026 0.0028 0.0035
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0019 0.0031
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0042 0.0085 0.019
Schistosoma mansoni P2X receptor subunit 0.007 0.0183 0.0227
Echinococcus multilocularis lamin 0.0054 0.0128 0.0211
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.008
Schistosoma mansoni histone deacetylase hda2 0.021 0.068 0.0843
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0023 0.0019 0.0031
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 0.1039 0.1288
Onchocerca volvulus 0.0238 0.078 0.1873
Echinococcus granulosus enteropeptidase 0.0048 0.0107 0.026
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0454 0.1544 0.2542
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0017 0.0021
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0107 0.0317 0.0386
Entamoeba histolytica P-glycoprotein-2 0.0036 0.0066 0.04
Schistosoma mansoni amine GPCR 0.0042 0.0085 0.0105
Trypanosoma brucei Calpain-like protein 2 0.0026 0.0028 0.0035
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0072 0.0191 0.0237
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0008
Trypanosoma cruzi subtilisin peptidase 0.0071 0.0188 0.0236
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0066 0.0169
Onchocerca volvulus 0.0047 0.0103 0.0235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Brugia malayi hypothetical protein 0.0048 0.0107 0.0133
Brugia malayi Metabotropic glutamate receptor precursor. 0.0094 0.0271 0.0335
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0039 0.0049
Trypanosoma brucei histone deacetylase 4 0.021 0.068 0.0854
Leishmania major C-8 sterol isomerase-like protein 0.2266 0.7956 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0222 0.0722 0.0895
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Brugia malayi Histone deacetylase 1 0.0352 0.1182 0.1465
Echinococcus granulosus tachykinin peptides receptor 99D 0.0042 0.0085 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0507 0.1732 0.4507
Plasmodium vivax calpain, putative 0.0086 0.0241 0.1771
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.0928 0.115
Onchocerca volvulus 0.0028 0.0038 0.0076
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0023 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0168 0.053 0.0657
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0187 0.0598 0.0984
Onchocerca volvulus 0.0037 0.0068 0.0149
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0026 0.0028 0.0035
Echinococcus granulosus intermediate filament protein 0.0054 0.0128 0.031
Brugia malayi transcriptional regulator, Sir2 family protein 0.0098 0.0286 0.0354
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0147 0.0456 0.1185
Schistosoma mansoni hypothetical protein 0.0678 0.2336 0.2896
Echinococcus granulosus fmrfamide receptor 0.0042 0.0085 0.0205
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Brugia malayi proprotein convertase 2 0.0071 0.0188 0.0233
Onchocerca volvulus 0.0023 0.0019 0.0031
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0107 0.0177
Brugia malayi Cathepsin L-like precursor 0.0047 0.0103 0.0128
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.007 0.0184 0.0419
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0017 0.0021
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0077 0.0095
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0011 0.0018
Mycobacterium ulcerans beta-lactamase 0.0222 0.0722 0.0712
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0222 0.0722 0.0895
Toxoplasma gondii LsmAD domain-containing protein 0.0134 0.041 0.0968
Echinococcus granulosus carbonic anhydrase 0.0084 0.0235 0.0568
Brugia malayi calpain 7 0.0086 0.0241 0.0299
Trypanosoma brucei C-8 sterol isomerase, putative 0.2266 0.7956 1
Leishmania major short chain dehydrogenase-like protein 0.0023 0.0019 0.001
Echinococcus multilocularis G protein coupled receptor 139 0.0042 0.0085 0.0139
Trichomonas vaginalis histone deacetylase, putative 0.0352 0.1182 0.3076
Echinococcus granulosus beta LACTamase domain containing family member 0.0222 0.0722 0.1746
Trypanosoma brucei histone deacetylase 2 0.0126 0.0383 0.0481
Echinococcus multilocularis neuropeptide Y receptor 0.0042 0.0085 0.0139
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0052 0.0086
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0077 0.0066
Echinococcus granulosus retinol dehydrogenase 11 0.0023 0.0019 0.0046
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1103 0.3842 0.4763
Brugia malayi neuroendocrine convertase 1 precursor 0.0071 0.0188 0.0233
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0023 0.0019 0.0023
Brugia malayi Cytochrome P450 family protein 0.0023 0.0018 0.0023
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.0048 0.0107 0.0133
Entamoeba histolytica P-glycoprotein-1 0.0036 0.0066 0.04
Onchocerca volvulus 0.0037 0.0068 0.0149
Echinococcus multilocularis histone deacetylase 3 0.0352 0.1182 0.1946
Echinococcus multilocularis p2X purinoceptor 4 0.007 0.0183 0.0302
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0066 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0017 0.0021
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0124 0.0378 0.0899
Schistosoma mansoni biogenic amine (5HT) receptor 0.0042 0.0085 0.0105
Echinococcus granulosus geminin 0.0678 0.2336 0.5646
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Toxoplasma gondii PAN domain-containing protein 0.0037 0.0068 0.0138
Giardia lamblia Alanyl dipeptidyl peptidase 0.0124 0.0378 0.2268
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0084 0.0235 0.0291
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Echinococcus multilocularis membrane bound transcription factor site 1 0.0071 0.0188 0.031
Onchocerca volvulus 0.0042 0.0085 0.019
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0011 0.0035
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0071 0.0188 0.0233
Giardia lamblia Hypothetical protein 0.0023 0.0019 0.0051
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0023 0.0019 0.0031
Brugia malayi transcriptional regulator, Sir2 family protein 0.0478 0.1629 0.2019
Plasmodium falciparum plasmepsin III 0.007 0.0184 0.134
Trichomonas vaginalis glucosylceramidase, putative 0.1103 0.3842 1
Entamoeba histolytica hypothetical protein, conserved 0.0124 0.0378 0.2317
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Echinococcus multilocularis fmrfamide receptor 0.0042 0.0085 0.0139
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0011 0.0035
Trypanosoma brucei prolyl endopeptidase 0.1187 0.4138 0.5201
Loa Loa (eye worm) carbonic anhydrase 3 0.0179 0.0571 0.0708
Brugia malayi Dopamine receptor protein 2 0.0042 0.0085 0.0105
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Echinococcus granulosus carbonic anhydrase II 0.0179 0.0571 0.138
Schistosoma mansoni hypothetical protein 0.0069 0.0181 0.0225
Toxoplasma gondii histone deacetylase HDAC3 0.0352 0.1182 0.2838
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Plasmodium falciparum cysteine proteinase falcipain 3 0.0047 0.0103 0.0733
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0107 0.0317 0.0766
Toxoplasma gondii microneme protein, putative 0.0037 0.0068 0.0138
Trichomonas vaginalis steroid dehydrogenase, putative 0.0023 0.0019 0.0048
Onchocerca volvulus 0.0037 0.0068 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0124 0.0378 0.0468
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0042 0.0085 0.0139
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0341 0.0428
Entamoeba histolytica hypothetical protein 0.0023 0.0019 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Loa Loa (eye worm) hypothetical protein 0.0217 0.0705 0.0874
Loa Loa (eye worm) transcriptional regulator 0.0098 0.0286 0.0354
Trypanosoma brucei SIR2-like protein 4, putative 0.0098 0.0286 0.0358
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0023 0.0019 0.0031
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0019 0.0031
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0066 0.0159
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0071 0.0188 0.0178
Mycobacterium ulcerans lipase LipD 0.0222 0.0722 0.0712
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0124 0.0378 0.0468
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0052 0.0086
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0038 0.0232
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus granulosus cathepsin l1 0.0034 0.0059 0.0143
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Echinococcus granulosus tm gpcr rhodopsin 0.0042 0.0085 0.0205
Mycobacterium ulcerans short chain dehydrogenase 0.1676 0.587 0.5865
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0095
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0042 0.0085 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0023 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0048 0.0107 0.0133
Onchocerca volvulus 0.0037 0.0068 0.0149
Brugia malayi Pre-SET motif family protein 0.0064 0.0165 0.0205
Entamoeba histolytica short chain dehydrogenase family protein 0.0023 0.0019 0.0113
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0077 0.0066
Echinococcus granulosus glutamate receptor subunit protein glur 0.0029 0.004 0.0097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Brugia malayi Cell death protein 3 precursor 0.0128 0.0392 0.0486
Brugia malayi steroid hormone receptor 0.0023 0.0017 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Onchocerca volvulus Cell death protein 3 homolog 0.0128 0.0392 0.0933
Plasmodium vivax aspartyl proteinase, putative 0.0147 0.0456 0.3392
Toxoplasma gondii histone deacetylase HDAC5 0.0126 0.0383 0.0903
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0071 0.0188 0.0233
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0023 0.0019 0.0023
Echinococcus multilocularis neuropeptide Y receptor 0.0042 0.0085 0.0139
Brugia malayi G-protein coupled receptor 0.0042 0.0085 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0141 0.0435 0.0547
Toxoplasma gondii subtilisin SUB6 0.0071 0.0188 0.043
Brugia malayi glutathione reductase 0.004 0.0079 0.0097
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0105 0.0255
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0036 0.0066 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0101 0.0295 0.0485
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0017 0.0021
Brugia malayi Smad1 0.0033 0.0052 0.0065
Schistosoma mansoni calpain-2 (C02 family) 0.0026 0.0028 0.0035
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0006 0.0015
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0019 0.0046
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0454 0.1544 0.1914
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0023 0.0019 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0038 0.0048
Loa Loa (eye worm) calpain D 0.0026 0.0028 0.0035
Schistosoma mansoni carbonyl reductase 0.0023 0.0019 0.0024
Mycobacterium ulcerans short-chain type oxidoreductase 0.0023 0.0019 0.0008
Plasmodium vivax histone deacetylase 1, putative 0.0352 0.1182 0.887
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Loa Loa (eye worm) hypothetical protein 0.0172 0.0547 0.0677
Loa Loa (eye worm) hypothetical protein 0.0454 0.1544 0.1914
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0028 0.0073
Echinococcus multilocularis oxidoreductase 0.0023 0.0019 0.0031
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Brugia malayi hypothetical protein 0.0267 0.0883 0.1095
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.0296 0.0285
Entamoeba histolytica hypothetical protein 0.0148 0.0461 0.283
Onchocerca volvulus 0.0023 0.0019 0.0031
Echinococcus multilocularis somatostatin receptor 0.0042 0.0085 0.0139
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0098 0.0286 0.2108
Onchocerca volvulus 0.0048 0.0107 0.0245
Echinococcus granulosus tissue type plasminogen activator 0.0081 0.0225 0.0543
Leishmania major cysteine peptidase A (CPA) 0.0047 0.0103 0.0116
Echinococcus multilocularis acylamino acid releasing enzyme 0.0124 0.0378 0.0622
Loa Loa (eye worm) ctsf protein 0.0047 0.0103 0.0128
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0242 0.0792 0.0982
Loa Loa (eye worm) fibroinase 0.0047 0.0103 0.0128
Leishmania major oligopeptidase b 0.0472 0.1608 0.201
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.029
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0077 0.0095
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Toxoplasma gondii subtilisin SUB7 0.0071 0.0188 0.043
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0023 0.0019 0.0008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0042 0.0085 0.0105
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Brugia malayi Dopamine receptor 0.0042 0.0085 0.0105
Trypanosoma brucei oxidoreductase-like protein 0.0023 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni biogenic amine receptor 0.0042 0.0085 0.0105
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0077 0.0198
Echinococcus multilocularis ATP binding cassette sub family B 0.0036 0.0064 0.0106
Schistosoma mansoni neuropeptide receptor 0.0042 0.0085 0.0105
Toxoplasma gondii subtilisin SUB11 0.0071 0.0188 0.043
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0019 0.0046
Schistosoma mansoni cathepsin F (C01 family) 0.0047 0.0103 0.0128
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0107 0.0133
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Plasmodium vivax ataxin-2 like protein, putative 0.0134 0.041 0.3048
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Loa Loa (eye worm) hypothetical protein 0.0064 0.0165 0.0205
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0059 0.0073
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0077 0.0096
Loa Loa (eye worm) hypothetical protein 0.0311 0.1039 0.1288
Loa Loa (eye worm) hypothetical protein 0.007 0.0184 0.0228
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0152 0.025
Mycobacterium ulcerans carveol-like dehydrogenase 0.0023 0.0019 0.0008
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0006 0.001
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0023 0.0019 0.0024
Echinococcus granulosus histone deacetylase 8 0.0126 0.0383 0.0927
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0023 0.0019 0.0023
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0019 0.0008
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0036 0.0066 0.0055
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.0302
Brugia malayi MH2 domain containing protein 0.0033 0.0052 0.0065
Echinococcus granulosus oxidoreductase 0.0023 0.0019 0.0046
Schistosoma mansoni carbonyl reductase 0.0023 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus granulosus protein kinase C gamma type 0.0051 0.0117 0.0283
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0475
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0019 0.0006 0.0007
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0023 0.0019 0.002
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0023 0.0019 0.0008
Schistosoma mansoni biogenic amine receptor 0.0042 0.0085 0.0105
Echinococcus multilocularis calpain A 0.0242 0.0793 0.1305
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0037 0.0068 0.0138
Echinococcus multilocularis neuropeptides capa receptor 0.0042 0.0085 0.0139
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0023 0.0019 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0627 0.2158 0.2674
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0017 0.0042
Loa Loa (eye worm) MH2 domain-containing protein 0.0478 0.1629 0.2019
Leishmania major hypothetical protein, unknown function 0.0026 0.0028 0.0022
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0026 0.0028 0.0035
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0101 0.0295 0.0485
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni amine GPCR 0.0042 0.0085 0.0105
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0086 0.0241 0.0302
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Toxoplasma gondii thioredoxin reductase 0.004 0.0079 0.0164
Brugia malayi histone deacetylase 1 (HD1) 0.0352 0.1182 0.1465
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0019 0.0096
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0301 0.0373
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0079 0.0068
Schistosoma mansoni cpg binding protein 0.003 0.0044 0.0054
Schistosoma mansoni multidrug resistance protein 0.0036 0.0066 0.0081
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0019 0.0046
Brugia malayi Ets-domain containing protein 0.0072 0.0193 0.0239
Echinococcus multilocularis histone deacetylase 6 0.021 0.068 0.112
Brugia malayi Melatonin receptor type 1A 0.0042 0.0085 0.0105
Echinococcus multilocularis sex peptide receptor 0.0042 0.0085 0.0139
Loa Loa (eye worm) hypothetical protein 0.0238 0.078 0.0967
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0102 0.0299 0.028
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0042 0.0085 0.0105
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0011 0.0026
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0017 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0128 0.0159
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0238 0.078 0.0967
Trypanosoma cruzi oligopeptidase b 0.0472 0.1608 0.202
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0315 0.1053 0.1734
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0548 0.1877 0.309
Schistosoma mansoni cathepsin D (A01 family) 0.0721 0.249 0.3086
Echinococcus multilocularis neuropeptide receptor 0.0042 0.0085 0.0139
Brugia malayi histone deacetylase 11 0.0126 0.0383 0.0475
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0077 0.0096
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0378 0.2802
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0101 0.0295 0.0712
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0105 0.0131
Plasmodium vivax steroid dehydrogenase, putative 0.0023 0.0019 0.0096
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0039 0.0049
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1062 0.3697 0.3691
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0106 0.0274
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.009 0.0218
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0084 0.0235 0.0291
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0023 0.0019 0.0024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Echinococcus granulosus prolyl endopeptidase 0.1187 0.4138 1
Echinococcus granulosus cysteine protease 0.0029 0.0038 0.0093
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0101 0.0295 0.0712
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0042 0.0085 0.0139
Brugia malayi beta-lactamase family protein 0.0222 0.0722 0.0895
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0042 0.0085 0.0105
Schistosoma mansoni hypothetical protein 0.0577 0.198 0.2454
Plasmodium falciparum glutathione reductase 0.004 0.0079 0.0546
Schistosoma mansoni carbonyl reductase 0.0023 0.0019 0.0024
Echinococcus multilocularis cathepsin L cysteine protease 0.0047 0.0103 0.017
Toxoplasma gondii cathepsin CPL 0.0047 0.0103 0.0224
Echinococcus multilocularis steroid dehydrogenase 0.0023 0.0019 0.0031
Onchocerca volvulus 0.0048 0.0107 0.0245
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0315 0.1053 0.2741
Loa Loa (eye worm) transcriptional regulator 0.0098 0.0286 0.0354
Loa Loa (eye worm) proprotein convertase 2 0.0071 0.0188 0.0233
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0478 0.1629 0.4238
Brugia malayi CXXC zinc finger family protein 0.0028 0.0038 0.0047
Echinococcus granulosus glutamate NMDA receptor subunit 0.0187 0.0598 0.1445
Echinococcus granulosus g protein coupled receptor 0.0042 0.0085 0.0205
Leishmania major cathepsin L-like protease 0.0047 0.0103 0.0116
Entamoeba histolytica prolyl oligopeptidase family protein 0.0124 0.0378 0.2317
Echinococcus granulosus cathepsin l cysteine peptidase 0.0047 0.0103 0.025
Entamoeba histolytica prolyl oligopeptidase family protein 0.0124 0.0378 0.2317
Echinococcus multilocularis serine threonine protein kinase 0.0051 0.0117 0.0193
Echinococcus multilocularis Mastin 0.0048 0.0107 0.0177
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Mycobacterium ulcerans NAD-dependent deacetylase 0.0098 0.0286 0.0275
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0011 0.0063
Entamoeba histolytica P-glycoprotein-2, putative 0.0036 0.0066 0.04
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.0271 0.0446
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0022 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.026 0.0249
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0017 0.0042
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0107 0.0317 0.0393
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0114 0.0341 0.2092
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0179 0.0571 0.0717
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Brugia malayi cathepsin L-like precursor 0.0034 0.0059 0.0073
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Leishmania major DNA polymerase kappa, putative 0.0039 0.0077 0.0083
Schistosoma mansoni inositol monophosphatase 0.0114 0.0341 0.0423
Plasmodium falciparum plasmepsin IV 0.0147 0.0456 0.3392
Loa Loa (eye worm) glutamate receptor 0.0031 0.0048 0.0059
Schistosoma mansoni alpha-1 adrenergic receptor 0.0042 0.0085 0.0105
Leishmania major short chain dehydrogenase, putative 0.0023 0.0019 0.001
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0017 0.0028
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Mycobacterium ulcerans hydrolase/amidase 0.0273 0.0905 0.0895
Schistosoma mansoni carbonic anhydrase-related 0.0084 0.0235 0.0291
Echinococcus granulosus WW domain containing oxidoreductase 0.0023 0.0019 0.0046
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0017 0.0021
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.029
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0066 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Brugia malayi prolyl oligopeptidase family protein 0.1187 0.4138 0.5129
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0023 0.0019 0.0113
Trypanosoma cruzi cysteine peptidase, putative 0.0153 0.048 0.0602
Trypanosoma cruzi kinesin, putative 0.006 0.015 0.0187
Loa Loa (eye worm) hypothetical protein 0.0069 0.0181 0.0225
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0032
Brugia malayi Protein kinase c protein 2 0.0049 0.0109 0.0135
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0017 0.0021
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) cysteine protease 0.0047 0.0103 0.0128
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.028 0.0928 0.115
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0023 0.0019 0.0023
Onchocerca volvulus 0.0047 0.0103 0.0235
Echinococcus granulosus calpain 7 C02 family 0.0086 0.0241 0.0582
Echinococcus granulosus metabotropic glutamate receptor 2 0.0081 0.0225 0.0544
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0124 0.0378 0.2317
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0084 0.0235 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0017 0.0021
Schistosoma mansoni memapsin-2 (A01 family) 0.007 0.0184 0.0228
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Loa Loa (eye worm) hypothetical protein 0.0202 0.0651 0.0807
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Schistosoma mansoni adenoreceptor 0.0042 0.0085 0.0105
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0042 0.0085 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Echinococcus granulosus neuropeptide Y receptor 0.0042 0.0085 0.0205
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0038 0.0048
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0071 0.0188 0.0233
Trypanosoma cruzi prefoldin subunit, putative 0.0069 0.0181 0.0227
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0029 0.004 0.0066
Brugia malayi Subtilase family protein 0.2297 0.8067 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Loa Loa (eye worm) aspartic protease BmAsp-1 0.007 0.0184 0.0228
Loa Loa (eye worm) histone deacetylase 3 0.0352 0.1182 0.1465
Trichomonas vaginalis inositol monophosphatase, putative 0.0114 0.0341 0.0887
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Loa Loa (eye worm) trypsin family protein 0.0048 0.0107 0.0133
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0023 0.0019 0.0023
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.009 0.0256 0.0318
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0028 0.0073
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0086 0.0241 0.0302
Schistosoma mansoni myelin transcription factor 1 myt1 0.0107 0.0317 0.0393
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0022 0.0016 0.0027
Schistosoma mansoni ATP-binding cassette transporter 0.0079 0.0217 0.0269
Echinococcus multilocularis inositol monophosphatase 1 0.0114 0.0341 0.0562
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0107 0.0133
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0165 0.0272
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0048 0.0107 0.0133
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0077 0.0095
Echinococcus granulosus Smad4 0.0033 0.0052 0.0127
Trypanosoma cruzi histone deacetylase 1, putative 0.0352 0.1182 0.1485
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0124 0.0378 0.0622
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0017 0.0028
Onchocerca volvulus 0.0047 0.0103 0.0235
Echinococcus granulosus furin 0.0071 0.0188 0.0455
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0077 0.0066
Brugia malayi Dehydrogenases, short chain protein 30 0.0023 0.0019 0.0024
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.035 0.0577
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0017 0.0021
Onchocerca volvulus 0.007 0.0184 0.043
Mycobacterium ulcerans ketoacyl reductase 0.0023 0.0019 0.0008
Toxoplasma gondii subtilisin SUB8 0.0071 0.0188 0.043
Mycobacterium tuberculosis Possible oxidoreductase 0.0023 0.0019 0.0008
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Leishmania major cathepsin L-like protease 0.0153 0.048 0.059
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0036 0.0066 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Loa Loa (eye worm) hypothetical protein 0.0222 0.0722 0.0895
Plasmodium falciparum histone deacetylase 1 0.0352 0.1182 0.887
Loa Loa (eye worm) multidrug resistance protein 3 0.0036 0.0066 0.0081
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0019 0.0008
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.0042 0.0085 0.0139
Onchocerca volvulus 0.0023 0.0019 0.0031
Echinococcus multilocularis lamin dm0 0.0054 0.0128 0.0211
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0124 0.0378 0.0474
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Echinococcus multilocularis retinol dehydrogenase 13 0.0023 0.0019 0.0031
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0038 0.0048
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0107 0.0317 0.0522
Leishmania major hypothetical protein, conserved 0.0023 0.0019 0.001
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Leishmania major kinesin, putative 0.006 0.015 0.0175
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0145 0.0182
Loa Loa (eye worm) hypothetical protein 0.0352 0.1182 0.1465
Brugia malayi Pepsin A precursor 0.007 0.0184 0.0228
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0017 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0241 0.0302
Trypanosoma cruzi short chain dehydrogenase, putative 0.0023 0.0019 0.0023
Leishmania major sir2-family protein-like protein 0.0098 0.0286 0.0346
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.0066 0.0159
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0017 0.0028
Echinococcus multilocularis carbonic anhydrase 0.0084 0.0235 0.0387
Toxoplasma gondii subtilisin SUB1 0.0071 0.0188 0.043
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Echinococcus granulosus glycoprotein Antigen 5 0.0048 0.0107 0.026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0038 0.0047
Entamoeba histolytica hypothetical protein 0.0048 0.0106 0.0646
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Plasmodium falciparum plasmepsin II 0.0147 0.0456 0.3392
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0029 0.004 0.0066
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0081 0.0225 0.037
Trichomonas vaginalis abcb9, putative 0.0036 0.0066 0.0169
Leishmania major carbonic anhydrase-like protein 0.0179 0.0571 0.0705
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.002
Plasmodium falciparum steroid dehydrogenase, putative 0.0023 0.0019 0.0096
Mycobacterium tuberculosis Probable lipase LipD 0.0222 0.0722 0.0712
Plasmodium falciparum plasmepsin VIII, putative 0.007 0.0184 0.134
Echinococcus multilocularis histone deacetylase 7 0.021 0.068 0.112
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0478 0.1629 0.2046
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0028 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.0153 0.048 0.0602
Echinococcus multilocularis fmrfamide receptor 0.0042 0.0085 0.0139
Trypanosoma cruzi histone deacetylase, putative 0.021 0.068 0.0854
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0017 0.0028
Schistosoma mansoni ets-related 0.022 0.0714 0.0885
Brugia malayi endoprotease bli-4 precursor 0.0071 0.0188 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0019 0.0008
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0472 0.1608 0.1599
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Echinococcus granulosus retinol dehydrogenase 11 0.0023 0.0019 0.0046
Onchocerca volvulus 0.0023 0.0019 0.0031
Trypanosoma cruzi oligopeptidase b 0.0472 0.1608 0.202
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0038 0.0232
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0017 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0222 0.0722 0.0907
Schistosoma mansoni ap endonuclease 0.0021 0.0011 0.0013
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0048 0.0107 0.026
Loa Loa (eye worm) hypothetical protein 0.0361 0.1216 0.1508
Brugia malayi histone deacetylase 3 (HD3) 0.0352 0.1182 0.1465
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0017 0.0021
Loa Loa (eye worm) histone deacetylase 11 0.0126 0.0383 0.0475
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0029 0.0038 0.0048
Mycobacterium tuberculosis Probable lipase LipE 0.0222 0.0722 0.0712
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0071 0.0188 0.0178
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0048 0.0107 0.0133
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0017 0.0027
Onchocerca volvulus 0.0222 0.0722 0.1733
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0105 0.0174
Onchocerca volvulus 0.007 0.0184 0.043
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0454 0.1544 0.1914
Echinococcus granulosus inositol monophosphatase 1 0.0114 0.0341 0.0825
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0017 0.0021
Schistosoma mansoni Mername-AA248 (C02 family) 0.0089 0.0253 0.0313
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0077 0.0096
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0023 0.0019 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0073
Mycobacterium tuberculosis Conserved protein 0.0222 0.0722 0.0712
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0155 0.0374
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0084 0.0235 0.0291
Leishmania major p-glycoprotein 0.0036 0.0066 0.0069
Loa Loa (eye worm) beta-lactamase 0.0222 0.0722 0.0895
Loa Loa (eye worm) neuropeptide F receptor 0.0042 0.0085 0.0105
Echinococcus granulosus atrial natriuretic peptide receptor 0.0022 0.0016 0.0039
Echinococcus granulosus caspase 2 0.0128 0.0392 0.0947
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Plasmodium vivax subtilisin-like protease 2, putative 0.0071 0.0188 0.1373
Loa Loa (eye worm) hypothetical protein 0.0084 0.0234 0.029
Brugia malayi putative neuropeptide receptor NPR1 0.0042 0.0085 0.0105
Loa Loa (eye worm) dehydrogenase 0.0023 0.0019 0.0024
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0023 0.0019 0.0023
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Brugia malayi follicle stimulating hormone receptor 0.0042 0.0085 0.0105
Echinococcus granulosus neuropeptide receptor A26 0.0042 0.0085 0.0205
Loa Loa (eye worm) PAN domain-containing protein 0.0037 0.0068 0.0084
Mycobacterium tuberculosis Conserved protein 0.0222 0.0722 0.0712
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0105 0.0131
Toxoplasma gondii aspartyl protease 0.007 0.0184 0.0419
Onchocerca volvulus 0.0023 0.0017 0.0027
Schistosoma mansoni chromatin regulatory protein sir2 0.0098 0.0286 0.0354
Onchocerca volvulus 0.0054 0.0128 0.0295
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0077 0.0096
Schistosoma mansoni ran 0.0043 0.009 0.0112
Brugia malayi MH1 domain containing protein 0.0033 0.0052 0.0065
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0315 0.1053 0.2741
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Echinococcus multilocularis musashi 0.0054 0.0128 0.0211
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0101 0.0295 0.0712
Loa Loa (eye worm) histone deacetylase 0.021 0.068 0.0843
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Toxoplasma gondii aspartyl protease ASP1 0.0147 0.0456 0.1078
Trypanosoma cruzi conserved protein 0.0026 0.0028 0.0035
Schistosoma mansoni Smad4 0.0033 0.0052 0.0065
Leishmania major cathepsin L-like protease 0.0047 0.0103 0.0116
Toxoplasma gondii ABC1 family protein 0.0222 0.0722 0.1724
Echinococcus multilocularis G-protein coupled receptor, putative 0.0042 0.0085 0.0139
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0023 0.0019 0.0024
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0098 0.0286 0.1752
Echinococcus granulosus neuropeptide receptor 0.0042 0.0085 0.0205
Echinococcus multilocularis tyrosine kinase 0.0022 0.0016 0.0027
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0352 0.1182 0.3076
Loa Loa (eye worm) nuclear factor I 0.0018 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Schistosoma mansoni inositol monophosphatase 0.0114 0.0341 0.0423
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0073
Toxoplasma gondii carbonyl reductase 1, putative 0.0023 0.0019 0.002
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0023 0.0019 0.0008
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0023 0.0019 0.0023
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.086 0.2981 0.7205
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0059 0.0152
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus granulosus glutamate receptor NMDA 0.0154 0.0484 0.1169
Entamoeba histolytica calpain large subunit domain III containing protein 0.006 0.015 0.0916
Leishmania major dehydrogenase-like protein 0.0023 0.0019 0.001
Schistosoma mansoni opsin-like receptor 0.0042 0.0085 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0222 0.0722 0.0907
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.0302
Toxoplasma gondii PAN domain-containing protein 0.0344 0.1155 0.2773
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2266 0.7956 1
Trypanosoma cruzi histone deacetylase, putative 0.0126 0.0383 0.0481
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0071 0.0188 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Echinococcus granulosus histone deacetylase 7 0.021 0.068 0.1644
Schistosoma mansoni transcription factor LCR-F1 0.0148 0.0461 0.0572
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Schistosoma mansoni polycystin 1-related 0.002 0.0006 0.0008
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Toxoplasma gondii hypothetical protein 0.0124 0.0378 0.0889
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0059 0.0152
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0017 0.0028
Mycobacterium ulcerans hypothetical protein 0.0022 0.0015 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0138 0.0171
Brugia malayi hypothetical protein 0.0023 0.0019 0.0024
Brugia malayi Trypsin family protein 0.0048 0.0107 0.0133
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0023 0.0019 0.002
Schistosoma mansoni smad1 5 8 and 0.0033 0.0052 0.0065
Echinococcus multilocularis cpg binding protein 0.003 0.0044 0.0072
Toxoplasma gondii hypothetical protein 0.0026 0.0028 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Echinococcus granulosus p2X purinoceptor 4 0.007 0.0183 0.0443
Brugia malayi hypothetical protein 0.002 0.0006 0.0008
Echinococcus granulosus dro:myosuppressin receptor 0.0042 0.0085 0.0205
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Entamoeba histolytica cysteine protease, putative 0.0047 0.0103 0.0631
Trichomonas vaginalis abcb9, putative 0.0036 0.0066 0.0169
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0147 0.0456 0.0565
Leishmania major cathepsin L-like protease 0.0153 0.048 0.059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.028 0.0928 0.1527
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0017 0.0028
Treponema pallidum mcbG protein 0.0022 0.0015 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0222 0.0722 0.0712
Brugia malayi RE15519p 0.0042 0.0085 0.0105
Toxoplasma gondii aspartyl protease ASP3 0.0394 0.1332 0.3201
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0047 0.0103 0.0733
Onchocerca volvulus 0.0037 0.0068 0.0149
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0152 0.0141
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Echinococcus multilocularis histone deacetylase 6 0.021 0.068 0.112
Schistosoma mansoni lamin 0.0054 0.0128 0.0159
Loa Loa (eye worm) PAN domain-containing protein 0.0037 0.0068 0.0084
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0042 0.0085 0.0139
Plasmodium falciparum subtilisin-like protease 3 0.0071 0.0188 0.1373
Brugia malayi prolyl oligopeptidase family protein 0.0124 0.0378 0.0468
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Echinococcus granulosus neuropeptide s receptor 0.0042 0.0085 0.0205
Plasmodium falciparum cysteine proteinase falcipain 1 0.0029 0.0038 0.0243
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0042 0.0085 0.0105
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0141
Giardia lamblia Alanyl dipeptidyl peptidase 0.0124 0.0378 0.2268
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0036 0.0066 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0763 0.2637 0.6864
Brugia malayi Kringle domain containing protein 0.0081 0.0225 0.0278
Brugia malayi ABC transporter family protein 0.0036 0.0066 0.0081
Leishmania major histone deacetylase, putative 0.021 0.068 0.0842
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0027 0.0068
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0271 0.0336
Plasmodium vivax NAD-dependent deacetylase, putative 0.0098 0.0286 0.2108
Brugia malayi KE2 family protein 0.0069 0.0181 0.0225
Echinococcus granulosus 7tm_1 domain containing protein 0.0042 0.0085 0.0205
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Echinococcus multilocularis serotonin receptor 0.0042 0.0085 0.0139
Leishmania major hypothetical protein, conserved 0.0026 0.0028 0.0022
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0179 0.0571 0.0708
Toxoplasma gondii prefoldin subunit 6, putative 0.0069 0.0181 0.0413
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0079 0.0546
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Schistosoma mansoni glutamate receptor kainate 0.0079 0.0215 0.0267
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0297 0.0988 0.1627
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0179 0.0571 0.0717
Trichomonas vaginalis ABC transporter, putative 0.0036 0.0066 0.0169
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.009 0.0633
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0042 0.0085 0.0105
Mycobacterium tuberculosis Probable peptidase 0.0472 0.1608 0.1599
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0057 0.0138 0.0228
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0019 0.0031
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0017 0.0021
Trichomonas vaginalis calpain, putative 0.0026 0.0028 0.0073
Trypanosoma brucei calpain-like protein, putative 0.0086 0.0241 0.0302
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0023 0.0019 0.0113
Toxoplasma gondii hypothetical protein 0.0037 0.0068 0.0138
Leishmania major cathepsin L-like protease 0.0047 0.0103 0.0116
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0048 0.0107 0.0133
Loa Loa (eye worm) hypothetical protein 0.0048 0.0107 0.0133
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Echinococcus granulosus dnaJ subfamily B 0.0405 0.1371 0.3312
Echinococcus granulosus neuropeptide Y receptor 0.0042 0.0085 0.0205
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0023 0.0019 0.002
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0011 0.0013
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0027 0.0065
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0124 0.0378 0.0474
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0017 0.0021
Trypanosoma brucei cysteine peptidase C (CPC) 0.0107 0.0317 0.0398
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Trichomonas vaginalis histone deacetylase, putative 0.0352 0.1182 0.3076
Loa Loa (eye worm) hypothetical protein 0.015 0.0469 0.0582
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Schistosoma mansoni hypothetical protein 0.0678 0.2336 0.2896
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0081
Brugia malayi Cathepsin L-like precursor 0.0047 0.0103 0.0128
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0023 0.0019 0.0046
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0042 0.0085 0.0105
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0023 0.0019 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0023 0.0019 0.0247
Plasmodium falciparum ataxin-2 like protein, putative 0.0134 0.041 0.3048
Echinococcus granulosus neuropeptides capa receptor 0.0042 0.0085 0.0205
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0035
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0101 0.0295 0.0485
Schistosoma mansoni hypothetical protein 0.0029 0.004 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0042 0.0085 0.0205
Echinococcus multilocularis conserved hypothetical protein 0.0023 0.0019 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Echinococcus granulosus neuropeptide FF receptor 2 0.0042 0.0085 0.0205
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0017 0.0042
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Echinococcus granulosus cathepsin L 0.0029 0.0038 0.0093
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0084 0.0235 0.0291
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.2297 0.8067 1
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0341 0.0428
Leishmania major prefoldin subunit, putative 0.0069 0.0181 0.0215
Onchocerca volvulus 0.019 0.061 0.1461
Entamoeba histolytica hypothetical protein, conserved 0.0098 0.0286 0.1752
Echinococcus multilocularis carbonic anhydrase 0.0084 0.0235 0.0387
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Onchocerca volvulus 0.0071 0.0188 0.044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Brugia malayi Glutamate receptor 1 precursor 0.0079 0.0215 0.0267
Entamoeba histolytica P-glycoprotein-5 0.0036 0.0066 0.04
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0103 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Echinococcus multilocularis calpain 7 (C02 family) 0.0086 0.0241 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Echinococcus granulosus Protein kinase C brain isozyme 0.0057 0.0138 0.0334
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0023 0.0019 0.0023
Toxoplasma gondii PAN domain-containing protein 0.0037 0.0068 0.0138
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0066 0.0108
Plasmodium vivax aspartyl protease, putative 0.0394 0.1332 1
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.0271 0.0654
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0042 0.0085 0.0139
Giardia lamblia Hypothetical protein 0.0478 0.1629 1
Trichomonas vaginalis D-aminoacylase, putative 0.0222 0.0722 0.1879
Brugia malayi hypothetical protein 0.0148 0.0461 0.0572
Trichomonas vaginalis glucosylceramidase, putative 0.0724 0.2499 0.6505
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0042 0.0085 0.0139
Echinococcus multilocularis enteropeptidase 0.0048 0.0107 0.0177
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0315 0.1053 0.2741
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Onchocerca volvulus 0.0042 0.0085 0.019
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Plasmodium vivax vivapain-2 0.0047 0.0103 0.0733
Loa Loa (eye worm) melatonin receptor type 1A 0.0042 0.0085 0.0105
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0446 0.1515 0.1877
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0017 0.0021
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0478 0.1629 0.2046
Echinococcus multilocularis multidrug resistance protein 1 0.0036 0.0066 0.0108
Plasmodium vivax importin-beta 2, putative 0.0059 0.0145 0.1048
Loa Loa (eye worm) MBCTL1 0.0107 0.0317 0.0393
Schistosoma mansoni hypothetical protein 0.0627 0.2158 0.2674
Schistosoma mansoni calpain C (C02 family) 0.0086 0.0241 0.0299
Echinococcus multilocularis receptor type guanylyl cyclase 0.0022 0.0016 0.0027
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0042 0.0085 0.0105
Plasmodium falciparum carbonic anhydrase 0.0084 0.0235 0.1725
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0011 0.0013
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0066 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Schistosoma mansoni neuropeptide receptor 0.0042 0.0085 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0011 0.0013
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0341 0.0416
Schistosoma mansoni rab6-interacting 0.002 0.0006 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Brugia malayi Histone deacetylase family protein 0.021 0.068 0.0843
Loa Loa (eye worm) neuropeptide F receptor 0.0042 0.0085 0.0105
Plasmodium vivax histone deacetylase, putative 0.021 0.068 0.5083
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0023 0.0019 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0271 0.0336
Trypanosoma cruzi histone deacetylase 1, putative 0.0352 0.1182 0.1485
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0042 0.0085 0.0105
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0019
Brugia malayi intermediate filament protein 0.0054 0.0128 0.0159
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.007 0.0184 0.0228
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0124 0.0378 0.2317
Loa Loa (eye worm) glutathione reductase 0.004 0.0079 0.0097
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0032
Brugia malayi larval opioid receptor 0.0042 0.0085 0.0105
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0341 0.0428
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Toxoplasma gondii microneme protein MIC4 0.0037 0.0068 0.0138
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.009 0.0113
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0054 0.0128 0.0159
Echinococcus multilocularis rhodopsin orphan GPCR 0.0042 0.0085 0.0139
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0138 0.0171
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0036 0.0066 0.0169
Trypanosoma cruzi PAB1-binding protein , putative 0.0134 0.041 0.0515
Echinococcus multilocularis Smad4 0.0033 0.0052 0.0086
Plasmodium falciparum multidrug resistance protein 1 0.0036 0.0066 0.0448
Brugia malayi prolyl oligopeptidase family protein 0.0124 0.0378 0.0468
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0098 0.0286 0.0275
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0019 0.0046
Loa Loa (eye worm) RGC/RGC protein kinase 0.0022 0.0016 0.002
Brugia malayi calpain family protein 1 0.0228 0.0743 0.0921
Mycobacterium tuberculosis Probable oxidoreductase 0.1676 0.587 0.5865
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0472 0.1608 0.201
Leishmania major trypanothione reductase 0.004 0.0079 0.0085
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0019 0.0024
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0042 0.0085 0.0139
Schistosoma mansoni cathepsin D (A01 family) 0.0721 0.249 0.3086
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.009 0.0112
Echinococcus granulosus somatostatin receptor 0.0042 0.0085 0.0205
Trypanosoma brucei calpain, putative 0.0026 0.0028 0.0035
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0165 0.0272
Toxoplasma gondii subtilisin SUB9 0.0071 0.0188 0.043
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0124 0.0378 0.0982
Onchocerca volvulus 0.0047 0.0103 0.0235
Loa Loa (eye worm) hypothetical protein 0.0134 0.041 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0188 0.0488
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0036 0.0066 0.0133
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0011 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Leishmania major hypothetical protein, conserved 0.0222 0.0722 0.0896
Plasmodium falciparum calpain 0.0026 0.0028 0.0168
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0147 0.0456 0.075
Leishmania major histone deacetylase, putative 0.0352 0.1182 0.1474
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1187 0.4138 0.5194
Echinococcus multilocularis neuropeptides capa receptor 0.0042 0.0085 0.0139
Echinococcus multilocularis programmed cell death protein 0.0018 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Echinococcus granulosus glutamate receptor 2 0.0101 0.0295 0.0712
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.0233
Echinococcus multilocularis retinol dehydrogenase 11 0.0023 0.0019 0.0031
Schistosoma mansoni inhibitor of apoptosis protein 0.0454 0.1544 0.1914
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0042 0.0085 0.0105
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0317 0.0393
Brugia malayi calpain D 0.0026 0.0028 0.0035
Onchocerca volvulus 0.0222 0.0722 0.1733
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0019 0.0113
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0124 0.0378 0.0889
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0022 0.0016 0.002
Echinococcus granulosus neuroendocrine convertase 2 0.0071 0.0188 0.0455
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.0296 0.0285
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0077 0.0095
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0026 0.0028 0.0035
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0017 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0086 0.0241 0.0302
Entamoeba histolytica Ran family GTPase 0.0043 0.009 0.0551
Echinococcus granulosus Furin 1 0.0071 0.0188 0.0455
Plasmodium vivax plasmepsin IV, putative 0.0147 0.0456 0.3392
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0098 0.0286 0.0358
Trichomonas vaginalis penicillin-binding protein, putative 0.0222 0.0722 0.1879
Echinococcus granulosus histone acetyltransferase MYST2 0.0107 0.0317 0.0766
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0165 0.0205
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Brugia malayi oxidoreductase 0.0023 0.0019 0.0024
Trypanosoma brucei carbonic anhydrase-like protein 0.0179 0.0571 0.0717
Plasmodium vivax subtilisin-like protease 1 0.0071 0.0188 0.1373
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Schistosoma mansoni chromatin regulatory protein sir2 0.0478 0.1629 0.2019
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0023 0.0019 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0188 0.0488
Trypanosoma cruzi prolyl endopeptidase 0.1187 0.4138 0.5201
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0105 0.0131
Echinococcus granulosus histone deacetylase 3 0.0352 0.1182 0.2857
Schistosoma mansoni intermediate filament proteins 0.0054 0.0128 0.0159
Brugia malayi hypothetical protein 0.0022 0.0016 0.002
Schistosoma mansoni neuropeptide F-like receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.0271 0.0336
Loa Loa (eye worm) hypothetical protein 0.0172 0.0547 0.0677
Echinococcus granulosus snurportin 1 0.0627 0.2158 0.5214
Schistosoma mansoni hypothetical protein 0.0048 0.0105 0.0131
Brugia malayi calpain family protein 1 0.0228 0.0743 0.0921
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0225 0.0282
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0017 0.0021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0011 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0022
Schistosoma mansoni histone deacetylase 4 5 0.021 0.068 0.0843
Giardia lamblia Reductase, putative 0.0023 0.0019 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0222 0.0722 0.1879
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0148 0.0461 0.0759
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.026 0.0249
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Echinococcus multilocularis nmda type glutamate receptor 0.0184 0.0587 0.0966
Toxoplasma gondii cathepsin B 0.0107 0.0317 0.0743
Echinococcus granulosus hypothetical protein 0.0023 0.0019 0.0046
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0026 0.0028 0.0043
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0023 0.0019 0.0008
Onchocerca volvulus 0.0037 0.0068 0.0149
Schistosoma mansoni carbonic anhydrase-related 0.0084 0.0235 0.0291
Echinococcus multilocularis cathepsin L 0.0029 0.0038 0.0063
Brugia malayi aspartic protease BmAsp-2, identical 0.007 0.0184 0.0228
Echinococcus granulosus serotonin receptor 0.0042 0.0085 0.0205
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0036 0.0066 0.0159
Brugia malayi hypothetical protein 0.002 0.0006 0.0008
Schistosoma mansoni hypothetical protein 0.0048 0.0105 0.0131
Schistosoma mansoni metabotropic glutamate receptor 0.0081 0.0225 0.0279
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0086 0.0241 0.0302
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Brugia malayi neuropeptide F receptor 0.0042 0.0085 0.0105
Schistosoma mansoni biogenic amine receptor 0.0042 0.0085 0.0105
Brugia malayi celfurPC protein 0.0071 0.0188 0.0233
Giardia lamblia Transcriptional regulator, Sir2 family 0.0098 0.0286 0.1699
Onchocerca volvulus 0.0022 0.0016 0.0024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Echinococcus multilocularis neuropeptide s receptor 0.0042 0.0085 0.0139
Schistosoma mansoni chromatin regulatory protein sir2 0.0098 0.0286 0.0354
Trypanosoma brucei antigen, putative 0.0086 0.0241 0.0302
Giardia lamblia DINP protein human, muc B family 0.0039 0.0077 0.0408
Toxoplasma gondii histone deacetylase HDAC1 0.021 0.068 0.1622
Onchocerca volvulus 0.0042 0.0085 0.019
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0026 0.0028 0.0035
Onchocerca volvulus 0.0037 0.0068 0.0149
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0029 0.0038 0.0048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0038 0.0048
Schistosoma mansoni P2X receptor subunit 0.007 0.0183 0.0227
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Brugia malayi Protein kinase domain containing protein 0.0081 0.0225 0.0278
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0047 0.0103 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0019 0.0023
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.009 0.0113
Loa Loa (eye worm) glutamate receptor 0.0094 0.0271 0.0335
Schistosoma mansoni neuropeptide f receptor 76f 0.0042 0.0085 0.0105
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0472 0.1608 0.202
Loa Loa (eye worm) hypothetical protein 0.1158 0.4036 0.5002
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0017 0.0021
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0124 0.0378 0.0468
Loa Loa (eye worm) hypothetical protein 0.0045 0.0097 0.012
Loa Loa (eye worm) Smad1 0.0033 0.0052 0.0065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0017 0.0042
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0036 0.0064 0.0155
Onchocerca volvulus 0.0034 0.0059 0.0128
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0079 0.0098
Leishmania major histone deacetylase, putative 0.021 0.068 0.0842
Trypanosoma cruzi cysteine proteinase, putative 0.0029 0.0038 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.015 0.0469 0.0582
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488
Trichomonas vaginalis hypothetical protein 0.0026 0.0028 0.0073
Loa Loa (eye worm) histone deacetylase 7A 0.021 0.068 0.0843
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0017 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0042 0.0085 0.0205
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0098 0.0286 0.2108
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.006 0.0149 0.0361
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0297 0.0988 0.1225
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Echinococcus granulosus nmda type glutamate receptor 0.0177 0.0563 0.136
Brugia malayi Cytochrome P450 family protein 0.0071 0.0189 0.0234
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0077 0.0126
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0179 0.0571 0.0708
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0017 0.0021
Loa Loa (eye worm) prolyl oligopeptidase 0.0124 0.0378 0.0468
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0093
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0022 0.0016 0.002
Loa Loa (eye worm) calpain family protein 1 0.0228 0.0743 0.0921
Brugia malayi calpain 5 0.0026 0.0028 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0026 0.0028 0.0035
Plasmodium falciparum histone deacetylase 2 0.021 0.068 0.5083
Schistosoma mansoni metabotropic glutamate receptor 0.0054 0.0127 0.0157
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1734 0.6075 1
Leishmania major silent information regulator 2, putative 0.0478 0.1629 0.2036
Brugia malayi Ets-domain containing protein 0.0072 0.0193 0.0239
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.0271 0.0654
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0023 0.0019 0.0008
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0006 0.001
Onchocerca volvulus 0.0036 0.0066 0.0144
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.026 0.0249
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0147 0.0456 0.0565
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0077 0.0096
Trypanosoma cruzi PAB1-binding protein , putative 0.0134 0.041 0.0515
Toxoplasma gondii subtilisin SUB10 0.0071 0.0188 0.043
Loa Loa (eye worm) RGC/RGC protein kinase 0.0022 0.0016 0.002
Onchocerca volvulus 0.0042 0.0085 0.019
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0019 0.0008
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0077 0.0126
Schistosoma mansoni site-1 peptidase (S08 family) 0.0071 0.0188 0.0233
Loa Loa (eye worm) hypothetical protein 0.0047 0.0103 0.0128
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1103 0.3842 0.4763
Echinococcus multilocularis 0.0071 0.0188 0.031
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0018 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Brugia malayi hypothetical protein 0.0042 0.0085 0.0105
Brugia malayi ORL1-like opioid receptor 0.0042 0.0085 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0017 0.0021
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.013 0.0161
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0019 0.0008
Brugia malayi Inositol-1 0.0114 0.0341 0.0423
Onchocerca volvulus Glucosylceramidase homolog 0.0724 0.2499 0.6034
Trypanosoma cruzi histone deacetylase, putative 0.021 0.068 0.0854
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0015 0.0069
Brugia malayi Papain family cysteine protease containing protein 0.0047 0.0103 0.0128
Echinococcus multilocularis glycoprotein Antigen 5 0.0048 0.0107 0.0177
Schistosoma mansoni smad1 5 8 and 0.0033 0.0052 0.0065
Mycobacterium ulcerans esterase/lipase LipP 0.0222 0.0722 0.0712
Schistosoma mansoni hypothetical protein 0.0026 0.0028 0.0035
Mycobacterium ulcerans Sir2-like regulatory protein 0.0098 0.0286 0.0275
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.002
Echinococcus multilocularis cysteine protease 0.0047 0.0103 0.017
Leishmania major subtilisin-like serine peptidase 0.0071 0.0188 0.0223
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0042 0.0085 0.0105
Echinococcus multilocularis smad 0.0033 0.0052 0.0086
Echinococcus granulosus programmed cell death protein 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0022 0.0016 0.0024
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0071 0.0188 0.0178
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0242 0.0792 0.0982
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0033 0.0041
Loa Loa (eye worm) doublecortin family protein 0.002 0.0006 0.0008
Toxoplasma gondii subtilisin SUB4 0.0071 0.0188 0.043
Toxoplasma gondii histone deacetylase HDAC4 0.0126 0.0383 0.0903
Schistosoma mansoni glutamate receptor kainate 0.0079 0.0215 0.0267
Brugia malayi G protein-coupled receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0073
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0376 0.1267 0.2085
Toxoplasma gondii hypothetical protein 0.0037 0.0068 0.0138
Schistosoma mansoni hypothetical protein 0.0103 0.0301 0.0373
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0019 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0103 0.0268
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0106 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0019
Brugia malayi Eukaryotic aspartyl protease family protein 0.007 0.0184 0.0228
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.028 0.0928 0.2242
Onchocerca volvulus 0.0042 0.0085 0.019
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Schistosoma mansoni rab6-interacting 0.002 0.0006 0.0008
Schistosoma mansoni hypothetical protein 0.0454 0.1544 0.1914
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0029 0.0038 0.0048
Brugia malayi Tachykinin-like peptides receptor 99D 0.0042 0.0085 0.0105
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0029 0.0038 0.0048
Loa Loa (eye worm) fli-1 protein 0.022 0.0714 0.0885
Echinococcus multilocularis orexin receptor type 2 0.0042 0.0085 0.0139
Loa Loa (eye worm) hypothetical protein 0.0094 0.0271 0.0336
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0222 0.0722 0.0712
Loa Loa (eye worm) TK/ROR protein kinase 0.0081 0.0225 0.0278
Echinococcus granulosus smad 0.0033 0.0052 0.0127
Leishmania major oxidoreductase-like protein 0.0023 0.0019 0.001
Brugia malayi Glutamate receptor 2 precursor 0.0079 0.0215 0.0267
Trypanosoma brucei Calpain-like protein CALP1.3 0.0026 0.0028 0.0035
Onchocerca volvulus 0.0047 0.0103 0.0235
Entamoeba histolytica hypothetical protein 0.0022 0.0016 0.0097
Mycobacterium tuberculosis Probable histidinol dehydrogenase HisD (HDH) 0.2843 1 1
Brugia malayi Dehydrogenases, short chain protein 2 0.0023 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0103 0.0301 0.0373
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0019 0.0024
Echinococcus granulosus cathepsin L cysteine proteinase 0.0047 0.0103 0.025
Entamoeba histolytica cysteine protease, putative 0.0029 0.0038 0.0232
Trypanosoma cruzi hypothetical protein, conserved 0.0124 0.0378 0.0474
Loa Loa (eye worm) hypothetical protein 0.0042 0.0085 0.0105
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0352 0.1182 0.3076
Trypanosoma cruzi extracellular receptor, putative 0.0022 0.0016 0.002
Brugia malayi Serotonin receptor 0.0042 0.0085 0.0105
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.0081
Trypanosoma cruzi kinesin, putative 0.006 0.015 0.0187
Loa Loa (eye worm) hypothetical protein 0.0113 0.0335 0.0416
Brugia malayi Cathepsin L-like precursor 0.0034 0.0059 0.0073
Leishmania major short chain dehydrogenase/reductase, putative 0.0023 0.0019 0.001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0077 0.0083
Onchocerca volvulus 0.0064 0.0165 0.0385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.0271 0.064
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0023 0.0019 0.0024
Schistosoma mansoni DNA polymerase eta 0.0039 0.0077 0.0095
Onchocerca volvulus 0.0037 0.0068 0.0149
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0023 0.0019 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0153 0.048 0.0602
Onchocerca volvulus Cathepsin L homolog 0.0047 0.0103 0.0235
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0019 0.0008
Onchocerca volvulus 0.0023 0.0019 0.0031
Trypanosoma cruzi prefoldin subunit, putative 0.0069 0.0181 0.0227
Schistosoma mansoni growth hormone secretagogue receptor 0.0042 0.0085 0.0105
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1187 0.4138 0.5129
Plasmodium vivax prefoldin subunit 6, putative 0.0069 0.0181 0.1321
Schistosoma mansoni biogenic amine (5HT) receptor 0.0042 0.0085 0.0105
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0017 0.0042
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0019 0.0008
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0124 0.0378 0.0468
Schistosoma mansoni amine GPCR 0.0042 0.0085 0.0105
Brugia malayi Histone deacetylase family protein 0.021 0.068 0.0843
Entamoeba histolytica prefoldin subunit 6, putative 0.0069 0.0181 0.111
Trichomonas vaginalis calpain, putative 0.0026 0.0028 0.0073
Echinococcus multilocularis inhibitor of apoptosis protein 0.0454 0.1544 0.2542
Brugia malayi Guanylyl cyclase protein 23 0.0022 0.0016 0.002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0042 0.0085 0.0105
Schistosoma mansoni cercarial elastase (S01 family) 0.0048 0.0107 0.0133
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0066 0.0108
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0023 0.0019 0.0024
Echinococcus granulosus neuropeptides capa receptor 0.0042 0.0085 0.0205
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0222 0.0722 0.0895
Loa Loa (eye worm) hypothetical protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0026 0.0028 0.0073
Brugia malayi PAN domain containing protein 0.0037 0.0068 0.0084
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0043 0.0088 0.0109
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0023 0.0019 0.0031
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0023 0.0019 0.001
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0019 0.0024
Brugia malayi aspartic protease BmAsp-1, identical 0.007 0.0184 0.0228
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0024
Echinococcus granulosus alpha 1A adrenergic receptor 0.0042 0.0085 0.0205
Entamoeba histolytica histone deacetylase, putative 0.0352 0.1182 0.7258
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0023 0.0019 0.0023
Onchocerca volvulus 0.0023 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.0142 0.0439 0.0544
Plasmodium falciparum plasmepsin X 0.0394 0.1332 1
Echinococcus multilocularis histone deacetylase 6 0.021 0.068 0.112
Loa Loa (eye worm) aspartyl protease 6 0.007 0.0184 0.0228
Schistosoma mansoni carbonic anhydrase 0.0084 0.0235 0.0291
Echinococcus multilocularis calpain family protein 1, d 0.0168 0.053 0.0873
Loa Loa (eye worm) hypothetical protein 0.0315 0.1053 0.1306
Echinococcus granulosus cathepsin b 0.0311 0.1039 0.2511
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0023 0.0019 0.0048
Toxoplasma gondii subtilisin SUB5 0.0071 0.0188 0.043
Echinococcus granulosus 7TM GPCR rhodopsin 0.0042 0.0085 0.0205
Brugia malayi hypothetical protein 0.0023 0.0019 0.0024
Echinococcus granulosus calpain A 0.0086 0.0241 0.0582
Schistosoma mansoni amine GPCR 0.0042 0.0085 0.0105
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0071 0.0188 0.0455
Schistosoma mansoni lamin 0.0054 0.0128 0.0159
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.026 0.0249
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0124 0.0378 0.0982
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0036 0.0066 0.0108
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0141
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0193 0.0318
Trichomonas vaginalis esterase, putative 0.0222 0.0722 0.1879
Echinococcus granulosus apoptotic protease activating factor 1 0.0128 0.0392 0.0947
Schistosoma mansoni calpain (C02 family) 0.0086 0.0241 0.0299
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0021
Onchocerca volvulus 0.0023 0.0019 0.0031
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0023 0.0019 0.0008
Onchocerca volvulus 0.0037 0.0068 0.0149
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0147 0.0456 0.1078
Echinococcus multilocularis nmda type glutamate receptor 0.0177 0.0563 0.0927
Loa Loa (eye worm) oxidoreductase 0.0023 0.0019 0.0024
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0019 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) calpain family protein 1 0.0168 0.053 0.0657
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0071 0.0188 0.0488

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.6 nM The compound was tested for the concentration to inhibit 50% of Adenylyl cyclase activity in rat cortical membranes. ChEMBL. 9572897
Ki (binding) = 4.7 nM Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]-CHA binding to bovine brain cortical membranes. ChEMBL. 9572897
Ki (binding) = 1082 nM Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H]-(R)-PIA binding to rat testis membranes ChEMBL. 9572897
Ki (binding) = 7440 nM Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes. ChEMBL. 9572897
Max inhibition (functional) = 13.7 % Maximal % inhibition of adenylyl cyclase activity in rat cortical membranes at a concentration of 10 uM. ChEMBL. 9572897
Selectivity (binding) = 0.14 Inhibitory selectivity at Adenosine A3 receptor compared to Adenosine 2A receptor. ChEMBL. 9572897
Selectivity (binding) = 230 Inhibitory selectivity at Adenosine A3 receptor compared to Adenosine 1 receptor. ChEMBL. 9572897
Selectivity (binding) = 1582 Inhibitory selectivity at Adenosine 2A receptor compared to Adenosine 1 receptor. ChEMBL. 9572897

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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