Detailed information for compound 1984435

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 516.994 | Formula: C29H26ClFN4O2
  • H donors: 2 H acceptors: 4 LogP: 6.05 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(c1cnc2c(c1Nc1ccc(cn1)C1CCCN1C)cc(cc2)c1cc(F)c(c(c1)Cl)O)C1CC1
  • InChi: 1S/C29H26ClFN4O2/c1-35-10-2-3-25(35)18-7-9-26(33-14-18)34-27-20-11-17(19-12-22(30)29(37)23(31)13-19)6-8-24(20)32-15-21(27)28(36)16-4-5-16/h6-9,11-16,25,37H,2-5,10H2,1H3,(H,32,33,34)
  • InChiKey: XPUUSISYMIEIRQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens maternal embryonic leucine zipper kinase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Echinococcus multilocularis maternal embryonic leucine zipper kinase Get druggable targets OG5_133787 All targets in OG5_133787
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Echinococcus granulosus maternal embryonic leucine zipper kinase Get druggable targets OG5_133787 All targets in OG5_133787
Schistosoma japonicum gsx family homeobox protein; serine/threonine kinase Get druggable targets OG5_133787 All targets in OG5_133787
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Schistosoma japonicum ko:K08799 maternal embryonic leucine zipper kinase, putative Get druggable targets OG5_133787 All targets in OG5_133787
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_133787 All targets in OG5_133787
Schistosoma mansoni serine/threonine kinase Get druggable targets OG5_133787 All targets in OG5_133787
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.0494
Echinococcus multilocularis transcription factor Dp 1 0.0029 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.2379 0.239 0.7585
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0371 0.0357 0.0366
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.004 0.0221
Trypanosoma brucei polo-like protein kinase 0.0132 0.0115 0.0739
Plasmodium falciparum LCCL domain-containing protein 0.0047 0.0029 0.018
Echinococcus multilocularis cyclin t1 0.002 0.0001 0.0001
Schistosoma mansoni glutaminase 0.0175 0.0159 0.0163
Loa Loa (eye worm) cyclin domain-containing protein 0.002 0.0001 0.0005
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0193 0.0177 0.1136
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1536 0.1537 0.3588
Loa Loa (eye worm) hypothetical protein 0.0227 0.0211 0.0669
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0007 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.002 0.0001 0.0001
Trypanosoma brucei DNA polymerase eta, putative 0.0055 0.0037 0.0232
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.0077 0.0076
Trypanosoma brucei unspecified product 0.0038 0.0019 0.012
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.0077 0.0079
Schistosoma mansoni lipoxygenase 0.0085 0.0067 0.0069
Echinococcus multilocularis axis inhibition protein axin 0.0026 0.0007 0.0006
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0049 0.0031 0.0458
Echinococcus multilocularis cysteine protease 0.0028 0.0009 0.0008
Brugia malayi GnHR receptor homolog 0.4249 0.4283 1
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0062 0.0044 0.0043
Brugia malayi cyclin fold protein 1 variant b 0.002 0.0001 0.0003
Trichomonas vaginalis glutathione reductase, putative 0.0061 0.0043 0.0157
Loa Loa (eye worm) hypothetical protein 0.016 0.0143 0.0455
Loa Loa (eye worm) hypothetical protein 0.1834 0.1838 0.5833
Echinococcus granulosus histone deacetylase 6 0.088 0.0872 0.0895
Schistosoma mansoni histone deacetylase 4 5 0.088 0.0872 0.0895
Brugia malayi hypothetical protein 0.1176 0.1172 0.2736
Brugia malayi hypothetical protein 0.0844 0.0835 0.1951
Schistosoma mansoni hypothetical protein 0.0371 0.0357 0.0366
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0062 0.0044 0.0325
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0172 0.0155 0.0492
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0028 0.0029
Entamoeba histolytica hypothetical protein 0.0026 0.0007 0.0047
Echinococcus multilocularis cyclin y 0.002 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0057 0.0182
Brugia malayi Smad1 0.0133 0.0116 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus granulosus acetylcholinesterase 0.0365 0.0351 0.036
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.002 0.0001 0.0003
Schistosoma mansoni amine GPCR 0.0371 0.0357 0.0366
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0077 0.0059 0.0188
Leishmania major cyclin 0.016 0.0143 0.0919
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0558 0.0547 0.0561
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0227 0.0211 0.021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0143 0.0126 0.013
Mycobacterium leprae Polyketide synthase Pks13 0.0073 0.0055 0.0841
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0046 0.0028 0.0171
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Leishmania major C-8 sterol isomerase-like protein 0.102 0.1014 0.6556
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni bromodomain containing protein 0.0034 0.0015 0.0016
Schistosoma mansoni biogenic amine receptor 0.0371 0.0357 0.0366
Brugia malayi beta-lactamase family protein 0.0205 0.0189 0.0441
Mycobacterium leprae conserved hypothetical protein 0.0205 0.0189 0.2938
Plasmodium vivax hypothetical protein, conserved 0.004 0.0021 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0089 0.0072 0.0263
Brugia malayi Niemann-Pick C1 protein precursor 0.0188 0.0172 0.0402
Plasmodium vivax hypothetical protein, conserved 0.0182 0.0165 0.1063
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0062 0.0044 0.0045
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Mycobacterium tuberculosis Conserved protein 0.0205 0.0189 0.1436
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0019 0.0001 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.004 0.0021 0.0022
Onchocerca volvulus 0.0371 0.0357 0.131
Trichomonas vaginalis hypothetical protein 0.0024 0.0005 0.0019
Echinococcus granulosus cyclin t1 0.002 0.0001 0.0001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0075 0.0057 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0049 0.0031 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.0009 0.0034
Toxoplasma gondii UBA/TS-N domain-containing protein 0.002 0.0001 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0335 0.0321 0.0749
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0006 0.0028
Brugia malayi cytochrome P450 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0153 0.0136 0.0433
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.002 0.0001 0.0001
Echinococcus granulosus Polycystic kidney disease protein 0.0047 0.0029 0.0029
Plasmodium vivax SET domain protein, putative 0.0345 0.0331 0.2137
Leishmania major hypothetical protein, conserved 0.0055 0.0037 0.0233
Onchocerca volvulus 0.0371 0.0357 0.131
Echinococcus granulosus lysine specific demethylase 5B 0.0019 0.0001 0.0001
Loa Loa (eye worm) glutathione reductase 0.0175 0.0159 0.0504
Trichomonas vaginalis cyclins, putative 0.016 0.0143 0.0526
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0044 0.0026 0.0161
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0175 0.0159 0.1205
Schistosoma mansoni alpha-glucosidase 0.0178 0.0162 0.0166
Mycobacterium ulcerans thioesterase TesA 0.0041 0.0022 0.0329
Trypanosoma brucei unspecified product 0.0055 0.0037 0.0232
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0069 0.0051 0.0325
Trypanosoma cruzi CYC2-like cyclin, putative 0.016 0.0143 0.0922
Loa Loa (eye worm) ctsf protein 0.0028 0.0009 0.0029
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0089 0.0072 0.0263
Schistosoma mansoni loxhd1 0.0047 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Brugia malayi Melatonin receptor type 1A 0.0371 0.0357 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0119 0.0436
Schistosoma mansoni alpha glucosidase 0.0046 0.0028 0.0029
Brugia malayi Raf kinase 0.0026 0.0007 0.0017
Echinococcus multilocularis calcium activated potassium channel 0.0073 0.0055 0.0054
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0019 0.0001 0.0001
Echinococcus granulosus peptide allatostatin:somatostatin 0.0371 0.0357 0.0366
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0061 0.0043 0.0268
Brugia malayi chromobox protein homolog 3 0.0136 0.0119 0.0277
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0045
Brugia malayi Tachykinin-like peptides receptor 99D 0.0371 0.0357 0.0833
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0075 0.0057 0.0365
Schistosoma mansoni tyrosine kinase 0.0126 0.0109 0.0112
Echinococcus granulosus mitogen activated protein kinase 3 0.0046 0.0028 0.0029
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0021 0.0067
Brugia malayi Cytochrome P450 family protein 0.0027 0.0009 0.002
Toxoplasma gondii isocitrate dehydrogenase 0.0024 0.0006 0.003
Schistosoma mansoni nuclear receptor 0.0068 0.005 0.0051
Trypanosoma cruzi cdc2-related kinase 3 0.0193 0.0177 0.1139
Trypanosoma cruzi ISWI complex protein 0.0055 0.0037 0.0236
Schistosoma mansoni methyl-cpg binding protein mbd 0.0062 0.0044 0.0045
Toxoplasma gondii LsmAD domain-containing protein 0.0158 0.0141 0.0907
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Brugia malayi putative neuropeptide receptor NPR1 0.0371 0.0357 0.0833
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Mycobacterium ulcerans lipoprotein LpqF 0.0038 0.002 0.0294
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0001 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Entamoeba histolytica deoxycytidyl transferase, putative 0.0055 0.0037 0.0237
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0049 0.0031 0.0225
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.002 0.0001 0.0001
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 0.0758
Loa Loa (eye worm) DR-78 0.0068 0.005 0.0158
Loa Loa (eye worm) hypothetical protein 0.0081 0.0063 0.02
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Leishmania major extracellular receptor, putative 0.0033 0.0014 0.0084
Schistosoma mansoni zinc finger protein 0.0089 0.0071 0.0073
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0023
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.0026 0.0027
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0112 0.0095 0.0094
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0041 0.0022 0.0329
Echinococcus multilocularis musashi 0.0077 0.0059 0.0058
Loa Loa (eye worm) neuropeptide F receptor 0.0371 0.0357 0.1132
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.024 0.0224 0.0523
Schistosoma mansoni hypothetical protein 0.024 0.0224 0.023
Echinococcus granulosus metabotropic glutamate receptor 5 0.0358 0.0343 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Echinococcus granulosus oligomeric golgi complex subunit 3 0.002 0.0001 0.0001
Echinococcus multilocularis mothers against decapentaplegic 2 0.006 0.0042 0.0041
Echinococcus granulosus histone deacetylase 0.088 0.0872 0.0895
Echinococcus granulosus mitogen activated protein kinase 0.0046 0.0028 0.0029
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0322 0.0308 0.0316
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0207 0.0191 0.0446
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0102 0.0085 0.064
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0024 0.0005 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Plasmodium vivax vivapain-2 0.0028 0.0009 0.0054
Echinococcus granulosus cyclin B3 1 0.0083 0.0065 0.0067
Schistosoma mansoni chromobox protein 0.0242 0.0226 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Echinococcus granulosus survival motor neuron protein 1 0.1176 0.1172 0.1203
Loa Loa (eye worm) hypothetical protein 0.0846 0.0838 0.2659
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0143 0.0126 0.0125
Plasmodium falciparum cyclin 1 0.002 0.0001 0.0004
Loa Loa (eye worm) F/Y-rich family protein 0.0019 0.0001 0.0003
Echinococcus multilocularis expressed protein 0.0458 0.0445 0.0444
Onchocerca volvulus 0.0219 0.0203 0.0746
Schistosoma mansoni bromodomain containing protein 0.0248 0.0232 0.0238
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0046 0.0028 0.018
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0026 0.0007 0.0007
Brugia malayi A-kinase anchor protein 10, precursor 0.0026 0.0007 0.0017
Brugia malayi Serotonin receptor 0.2727 0.2743 0.6404
Echinococcus multilocularis cyclin y 0.002 0.0001 0.0001
Trichomonas vaginalis chromobox protein, putative 0.0242 0.0226 0.0831
Loa Loa (eye worm) hypothetical protein 0.006 0.0042 0.0134
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Echinococcus granulosus fetal alzheimer antigen falz 0.0094 0.0077 0.0079
Echinococcus multilocularis lysosomal alpha glucosidase 0.0207 0.0191 0.019
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Onchocerca volvulus Glucosylceramidase homolog 0.0362 0.0348 0.1279
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.0077 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0048 0.0177
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0143 0.0126 0.013
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0143 0.0126 0.013
Echinococcus granulosus regulator of G protein signaling 3 0.0026 0.0007 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0028 0.0102
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0552 0.054 0.1715
Mycobacterium tuberculosis Probable oxidoreductase 0.0445 0.0431 0.3291
Loa Loa (eye worm) cyclin domain-containing protein 0.002 0.0001 0.0005
Trypanosoma brucei beta lactamase 0.0038 0.002 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Echinococcus granulosus g protein coupled receptor 0.0371 0.0357 0.0366
Loa Loa (eye worm) CHromoDomain protein family member 0.0059 0.0041 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0177 0.0181
Onchocerca volvulus 0.0371 0.0357 0.131
Schistosoma mansoni phd finger protein 0.0019 0.0001 0.0001
Echinococcus granulosus phd finger protein 12 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0205 0.0189 0.06
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0656 0.0646 0.0645
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0046 0.0028 0.0102
Echinococcus granulosus g-protein coupled receptor 0.0371 0.0357 0.0366
Brugia malayi hypothetical protein 0.0109 0.0091 0.0213
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0234 0.0218 0.0217
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0001 0.0005
Echinococcus multilocularis serotonin transporter 0.0558 0.0547 0.0546
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus multilocularis chromobox protein 1 0.0242 0.0226 0.0225
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0037 0.0019 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0009 0.006
Brugia malayi jmjC domain containing protein 0.0075 0.0057 0.0134
Echinococcus multilocularis 0.0043 0.0025 0.0024
Mycobacterium tuberculosis Probable lipase LipE 0.0205 0.0189 0.1436
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0019 0.012
Schistosoma mansoni nuclear receptor nhr-48 0.0068 0.005 0.0051
Echinococcus multilocularis chromobox protein 1 0.0242 0.0226 0.0225
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0084 0.0066 0.0496
Echinococcus granulosus microtubule associated protein 2 0.9639 0.9741 1
Plasmodium falciparum amino acid transporter, putative 0.0095 0.0077 0.0494
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0049 0.0031 0.0202
Echinococcus granulosus lamin dm0 0.0077 0.0059 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0001 0.0002
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0132 0.0115 0.0118
Schistosoma mansoni myosin xvIII 0.0371 0.0357 0.0366
Schistosoma mansoni neuropeptide F-like receptor 0.0371 0.0357 0.0366
Schistosoma mansoni serine/threonine kinase 0.0161 0.0144 0.0148
Plasmodium vivax JmjC domain containing protein 0.0075 0.0057 0.0365
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.04 0.0386 0.2945
Schistosoma mansoni hypothetical protein 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus multilocularis histone deacetylase 3 0.1545 0.1546 0.1545
Brugia malayi hypothetical protein 0.002 0.0001 0.0003
Onchocerca volvulus 0.016 0.0143 0.0526
Echinococcus granulosus transportin 1 0.0024 0.0005 0.0005
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0079 0.0061 0.0194
Loa Loa (eye worm) hypothetical protein 0.0205 0.0189 0.06
Echinococcus granulosus inositol monophosphatase 1 0.0115 0.0098 0.0101
Onchocerca volvulus 0.002 0.0001 0.0005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0008 0.0048
Brugia malayi PHD-finger family protein 0.0019 0.0001 0.0002
Onchocerca volvulus Cyclin L homolog 0.002 0.0001 0.0005
Echinococcus multilocularis serotonin receptor 0.0846 0.0838 0.0837
Schistosoma mansoni hypothetical protein 0.0046 0.0028 0.0029
Schistosoma mansoni hypothetical protein 0.4655 0.4695 0.4819
Brugia malayi nuclear hormone receptor family member nhr-6 0.0068 0.005 0.0116
Echinococcus multilocularis kinesin family 1 0.0121 0.0103 0.0102
Treponema pallidum sodium- and chloride- dependent transporter 0.0558 0.0547 0.4065
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Brugia malayi ecdysone receptor 0.0068 0.005 0.0116
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0009 0.0049
Echinococcus granulosus para nitrobenzyl esterase 0.0062 0.0044 0.0045
Toxoplasma gondii cyclin 4, putative 0.002 0.0001 0.0004
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0026 0.0007 0.0023
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0055 0.0037 0.0228
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0068 0.005 0.0051
Echinococcus multilocularis cyclin B3 1 0.0083 0.0065 0.0064
Brugia malayi Cyclin C 0.002 0.0001 0.0003
Onchocerca volvulus 0.0205 0.0189 0.0694
Brugia malayi metabotropic glutamate receptor type 2 0.0145 0.0128 0.0299
Echinococcus multilocularis G protein coupled receptor 139 0.0371 0.0357 0.0356
Echinococcus granulosus atrial natriuretic peptide receptor 0.0033 0.0014 0.0015
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0095 0.0077 0.0076
Echinococcus multilocularis protein patched 0.0081 0.0063 0.0062
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.1176 0.1172 0.3718
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0068 0.005 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Trypanosoma cruzi polo-like protein kinase, putative 0.0132 0.0115 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0115 0.0118
Brugia malayi Histone deacetylase 1 0.1545 0.1546 0.3609
Loa Loa (eye worm) hypothetical protein 0.0167 0.0151 0.0478
Loa Loa (eye worm) doublecortin family protein 0.0047 0.0029 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Plasmodium vivax transportin, putative 0.0024 0.0005 0.0028
Brugia malayi intermediate filament protein 0.0077 0.0059 0.0138
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0052 0.0034 0.0506
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0335 0.0321 0.032
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0049 0.0031 0.0193
Toxoplasma gondii HEAT repeat-containing protein 0.0024 0.0005 0.0028
Echinococcus granulosus translocator protein 0.0637 0.0626 0.0643
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0027 0.0064
Echinococcus granulosus cyclins 0.0083 0.0065 0.0067
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0044 0.0026 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0143 0.0126 0.0401
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0371 0.0357 0.0366
Echinococcus granulosus lysosomal alpha glucosidase 0.0207 0.0191 0.0196
Schistosoma mansoni chromobox protein 0.0242 0.0226 0.0232
Loa Loa (eye worm) hypothetical protein 0.0106 0.0089 0.0282
Loa Loa (eye worm) inositol-1 0.0115 0.0098 0.0311
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0065 0.0047 0.0171
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0046 0.0028 0.0175
Treponema pallidum NADH oxidase 0.0061 0.0043 0.0243
Trypanosoma brucei importin beta-1 subunit, putative 0.0125 0.0108 0.0693
Schistosoma mansoni amine GPCR 0.0371 0.0357 0.0366
Schistosoma mansoni sodium/chloride dependent transporter 0.0558 0.0547 0.0561
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Entamoeba histolytica hypothetical protein 0.0322 0.0308 0.199
Echinococcus multilocularis mothers against decapentaplegic 6 0.006 0.0042 0.0041
Toxoplasma gondii ABC1 family protein 0.0205 0.0189 0.1217
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.0026 0.0027
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.0026 0.0025
Brugia malayi MH2 domain containing protein 0.1956 0.1962 0.458
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0001 0.0002
Brugia malayi hypothetical protein 0.0322 0.0308 0.0718
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0271
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0271
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0046 0.0028 0.0066
Trypanosoma brucei histone deacetylase 4 0.088 0.0872 0.5639
Mycobacterium tuberculosis Putative ferredoxin reductase 0.04 0.0386 0.2945
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0009 0.0049
Schistosoma mansoni cyclins 0.0083 0.0065 0.0067
Trypanosoma cruzi histone deacetylase, putative 0.088 0.0872 0.5639
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Brugia malayi nuclear receptor RXR 0.0076 0.0058 0.0135
Brugia malayi Cathepsin L-like precursor 0.0028 0.0009 0.0022
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0026 0.0007 0.0027
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.004 0.0021 0.0022
Brugia malayi Receptor family ligand binding region containing protein 0.0079 0.0061 0.0143
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0182 0.2834
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0059 0.0041 0.004
Mycobacterium ulcerans lipase LipD 0.0205 0.0189 0.2938
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0102 0.0084 0.1298
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0061 0.0043 0.0647
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0062 0.0044 0.0046
Plasmodium vivax SNF2 family N-terminal domain containing protein 0.0019 0.0001 0.000000000065333
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0143 0.0126 0.0401
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0445 0.0431 0.3291
Giardia lamblia Histone acetyltransferase GCN5 0.0061 0.0043 0.0267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0063 0.0045 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0021 0.0022
Echinococcus multilocularis aryl hydrocarbon receptor 0.0056 0.0038 0.0037
Echinococcus multilocularis orexin receptor type 2 0.0371 0.0357 0.0356
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0146 0.0129 0.0474
Onchocerca volvulus 0.0558 0.0547 0.2008
Brugia malayi nuclear hormone receptor family member odr-7 0.0068 0.005 0.0116
Schistosoma mansoni zinc finger protein 0.0068 0.005 0.0051
Brugia malayi MAP kinase sur-1 0.0046 0.0028 0.0065
Echinococcus granulosus hypothetical protein 0.1158 0.1154 0.1184
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0199 0.0182 0.1172
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0068 0.005 0.0049
Trichomonas vaginalis hypothetical protein 0.0027 0.0008 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0043 0.0271
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus Regulator of G protein signaling 20 0.0026 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Echinococcus granulosus cyclin b3 0.0083 0.0065 0.0067
Plasmodium falciparum thioredoxin reductase 0.0175 0.0159 0.1022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0268
Echinococcus multilocularis regulator of G protein signaling 3 0.0026 0.0007 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.1545 0.1546 0.5677
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0115 0.0097 0.0309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0155 0.0569
Brugia malayi histone deacetylase 1 (HD1) 0.1545 0.1546 0.3609
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0006 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0043 0.0271
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0024 0.0006 0.0006
Loa Loa (eye worm) beta-lactamase 0.0205 0.0189 0.06
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0089 0.0072 0.0263
Plasmodium vivax hypothetical protein, conserved 0.0205 0.0189 0.1217
Loa Loa (eye worm) hypothetical protein 0.0167 0.0151 0.0478
Loa Loa (eye worm) importin-beta domain-containing protein 0.0024 0.0005 0.0016
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0062 0.0044 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0028 0.0102
Echinococcus granulosus lipoxygenase domain containing protein 0.0047 0.0029 0.0029
Schistosoma mansoni importin-beta 2 0.0024 0.0005 0.0005
Loa Loa (eye worm) fibroinase 0.0028 0.0009 0.0029
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Brugia malayi TAR-binding protein 0.0211 0.0195 0.0455
Onchocerca volvulus Neuropeptide F receptor homolog 0.0371 0.0357 0.131
Echinococcus granulosus glutamate receptor 2 0.0033 0.0014 0.0015
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0006 0.0006
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0006 0.0021
Onchocerca volvulus 0.0143 0.0126 0.0464
Brugia malayi photoreceptor-specific nuclear receptor 0.0143 0.0126 0.0295
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Trichomonas vaginalis esterase, putative 0.0205 0.0189 0.0694
Plasmodium vivax importin-beta 2, putative 0.0125 0.0108 0.0693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Echinococcus granulosus tar DNA binding protein 0.0211 0.0195 0.02
Schistosoma mansoni hypothetical protein 0.0465 0.0452 0.0464
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Mycobacterium ulcerans polyketide synthase Pks13 0.0073 0.0055 0.0841
Echinococcus granulosus mothers against decapentaplegic 2 0.006 0.0042 0.0043
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0143 0.0126 0.013
Brugia malayi Regulator of G protein signaling domain containing protein 0.0026 0.0007 0.0017
Schistosoma mansoni hypothetical protein 0.4655 0.4695 0.4819
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0132 0.0115 0.0365
Loa Loa (eye worm) hypothetical protein 0.0075 0.0057 0.0182
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0211 0.0195 0.0619
Echinococcus granulosus cathepsin L cysteine proteinase 0.0028 0.0009 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Echinococcus granulosus ankyrin repeat protein 0.0106 0.0089 0.0091
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0172 0.0155 0.0995
Brugia malayi hypothetical protein 0.0158 0.0141 0.0329
Schistosoma mansoni aldehyde dehydrogenase 0.0199 0.0182 0.0187
Schistosoma mansoni ets-related 0.0141 0.0124 0.0127
Onchocerca volvulus 0.0041 0.0023 0.0084
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0205 0.0189 0.1436
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0335 0.0321 0.0329
Echinococcus multilocularis G1:S specific cyclin D1 0.002 0.0001 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0813 0.0805 0.1878
Trypanosoma cruzi cyclin, putative 0.016 0.0143 0.0922
Loa Loa (eye worm) malate dehydrogenase 0.0024 0.0005 0.0017
Brugia malayi neuropeptide F receptor 0.0371 0.0357 0.0833
Trypanosoma cruzi malate dehydrogenase, putative 0.0024 0.0005 0.003
Brugia malayi PHD-finger family protein 0.0019 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi histone deacetylase 11 0.0562 0.0551 0.1286
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0128 0.0111 0.0711
Brugia malayi jmjC domain containing protein 0.0301 0.0286 0.0667
Trichomonas vaginalis inhibitor of growth, putative 0.0019 0.0001 0.0003
Echinococcus multilocularis GPCR, family 3, C terminal 0.0046 0.0028 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0061 0.0043 0.0271
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0046 0.0028 0.0171
Mycobacterium ulcerans carboxylesterase, LipT 0.0062 0.0044 0.0663
Brugia malayi M-phase phosphoprotein, mpp8 0.004 0.0021 0.005
Echinococcus granulosus dna polymerase eta 0.0055 0.0037 0.0038
Schistosoma mansoni cyclin B3 0.0256 0.024 0.0247
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.013 0.0113 0.0116
Schistosoma mansoni hypothetical protein 0.0465 0.0452 0.0464
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0038 0.002 0.0294
Brugia malayi Doublecortin family protein 0.0047 0.0029 0.0067
Loa Loa (eye worm) hypothetical protein 0.006 0.0042 0.0132
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0371 0.0357 0.1132
Plasmodium vivax histone deacetylase 2, putative 0.088 0.0872 0.5639
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.002 0.0001 0.0004
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.04 0.0386 0.6028
Trypanosoma brucei cdc2-related kinase 3 0.0193 0.0177 0.1139
Leishmania major histone deacetylase, putative 0.1545 0.1546 1
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.002 0.0001 0.0003
Brugia malayi RNA binding protein 0.0211 0.0195 0.0455
Trypanosoma cruzi PAB1-binding protein , putative 0.0158 0.0141 0.0907
Leishmania major hypothetical protein, conserved 0.0024 0.0005 0.0024
Brugia malayi intracellular kinase 0.0172 0.0155 0.0362
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0024 0.0006 0.003
Mycobacterium ulcerans hypothetical protein 0.0119 0.0102 0.1575
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Echinococcus granulosus histone acetyltransferase KAT2B 0.0219 0.0203 0.0208
Schistosoma mansoni jumonji/arid domain-containing protein 0.0301 0.0286 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0028 0.0174
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Schistosoma mansoni hypothetical protein 0.0059 0.0041 0.0042
Leishmania major cathepsin L-like protease 0.0028 0.0009 0.0051
Loa Loa (eye worm) hypothetical protein 0.0076 0.0058 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0119 0.0436
Echinococcus granulosus Smad4 0.0133 0.0116 0.0119
Echinococcus granulosus cyclin G2 0.002 0.0001 0.0001
Brugia malayi Regulator of G protein signaling domain containing protein 0.0026 0.0007 0.0017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.004 0.0252
Schistosoma mansoni hypothetical protein 0.0154 0.0137 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Echinococcus granulosus histone deacetylase 3 0.1545 0.1546 0.1587
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Trypanosoma cruzi cdc2-related kinase 1 0.0193 0.0177 0.1139
Onchocerca volvulus 0.012 0.0103 0.0377
Loa Loa (eye worm) hypothetical protein 0.0055 0.0037 0.0116
Loa Loa (eye worm) hypothetical protein 0.0328 0.0313 0.0993
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0024 0.0005 0.0028
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0371 0.0357 0.0366
Echinococcus granulosus jumonji domain containing 1A 0.0075 0.0057 0.0059
Echinococcus granulosus cathepsin l cysteine peptidase 0.0028 0.0009 0.001
Loa Loa (eye worm) cyclin domain-containing protein 0.002 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Echinococcus multilocularis mothers against decapentaplegic 5 0.0133 0.0116 0.0115
Onchocerca volvulus Protein ultraspiracle homolog 0.0143 0.0126 0.0464
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0001 0.0002
Schistosoma mansoni amine GPCR 0.0371 0.0357 0.0366
Echinococcus multilocularis acetylcholinesterase 0.0365 0.0351 0.035
Plasmodium vivax hypothetical protein, conserved 0.0095 0.0077 0.0494
Loa Loa (eye worm) hypothetical protein 0.0465 0.0452 0.1436
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0335 0.0321 0.0329
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0075 0.0057 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Echinococcus multilocularis neuropeptide FF receptor 2 0.0371 0.0357 0.0356
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0024 0.0006 0.003
Onchocerca volvulus 0.0019 0.0001 0.0003
Loa Loa (eye worm) TK/EGFR protein kinase 0.0147 0.013 0.0412
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0172 0.0155 0.0154
Brugia malayi MH1 domain containing protein 0.0133 0.0116 0.0271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0143 0.0126 0.0401
Echinococcus granulosus chromobox protein 2 0.004 0.0021 0.0022
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Giardia lamblia Sgs1 DNA helicase, putative 0.0024 0.0006 0.0028
Echinococcus granulosus chromobox protein 1 0.0242 0.0226 0.0232
Onchocerca volvulus 0.0077 0.0059 0.0218
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni inositol monophosphatase 0.0115 0.0098 0.0101
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0001 0.0001
Echinococcus multilocularis GPCR, family 2 0.0465 0.0452 0.0452
Brugia malayi Type III restriction enzyme, res subunit family protein 0.004 0.0021 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0189 0.1217
Echinococcus granulosus GPCR family 2 0.0465 0.0452 0.0464
Brugia malayi Protein kinase domain containing protein 0.0031 0.0013 0.003
Schistosoma mansoni BC026374 protein (S09 family) 0.0062 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0137 0.0119 0.0379
Mycobacterium ulcerans glutaminase 0.0175 0.0159 0.2466
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0075 0.0057 0.0059
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0044 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0007 0.0007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0094 0.0077 0.0076
Onchocerca volvulus 0.0371 0.0357 0.131
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0008 0.0048
Echinococcus granulosus Niemann Pick C1 protein 0.0269 0.0254 0.0261
Entamoeba histolytica hypothetical protein 0.0033 0.0014 0.0093
Loa Loa (eye worm) hypothetical protein 0.0076 0.0058 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0001 0.0002
Loa Loa (eye worm) cyclin domain-containing protein 0.002 0.0001 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0143 0.0126 0.0295
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0143 0.0126 0.013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0271
Brugia malayi nuclear hormone receptor 0.0068 0.005 0.0116
Schistosoma mansoni DNA helicase recq1 0.0024 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1545 0.1546 0.4904
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.002 0.0001 0.0003
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0006 0.0031
Echinococcus granulosus 7TM GPCR rhodopsin 0.0371 0.0357 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0177 0.0181
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0012 0.007
Brugia malayi hypothetical protein 0.0167 0.0151 0.0352
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0028 0.0009 0.0054
Brugia malayi Guanylyl cyclase protein 23 0.0037 0.0019 0.0044
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0062 0.0044 0.0043
Schistosoma mansoni amine GPCR 0.0371 0.0357 0.0366
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0371 0.0357 0.131
Schistosoma mansoni tar DNA-binding protein 0.0211 0.0195 0.02
Echinococcus granulosus cathepsin l1 0.0028 0.0009 0.001
Schistosoma mansoni histone deacetylase hda2 0.0894 0.0886 0.091
Schistosoma mansoni SET domain protein 0.0037 0.0018 0.0019
Trichomonas vaginalis helicase, putative 0.005 0.0031 0.0116
Trichomonas vaginalis sucrase-isomaltase, putative 0.0046 0.0028 0.0102
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0371 0.0357 0.0366
Echinococcus granulosus uro adherence factor A 0.0019 0.0001 0.0001
Onchocerca volvulus 0.0028 0.0009 0.0034
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.004 0.0021 0.0138
Trichomonas vaginalis chromobox protein, putative 0.004 0.0021 0.0078
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0001 0.0005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.004 0.0249
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus carboxylesterase 5A 0.0365 0.0351 0.036
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0044 0.0026 0.0027
Leishmania major cathepsin L-like protease 0.0028 0.0009 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0335 0.0321 0.0329
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Onchocerca volvulus 0.0205 0.0189 0.0694
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0055 0.0037 0.0036
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0088 0.0565
Trypanosoma cruzi histone deacetylase, putative 0.088 0.0872 0.5639
Brugia malayi hypothetical protein 0.0039 0.0021 0.0048
Echinococcus multilocularis malate dehydrogenase 0.0024 0.0005 0.0005
Trichomonas vaginalis set domain proteins, putative 0.2707 0.2722 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0143 0.0126 0.013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0143 0.0126 0.0401
Trypanosoma cruzi extracellular receptor, putative 0.0033 0.0014 0.0087
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Loa Loa (eye worm) histone deacetylase 11 0.0562 0.0551 0.1747
Echinococcus multilocularis inositol monophosphatase 1 0.0115 0.0098 0.0097
Loa Loa (eye worm) bromodomain containing protein 0.007 0.0052 0.0164
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0143 0.0126 0.013
Brugia malayi Protein kinase domain containing protein 0.0193 0.0177 0.0413
Echinococcus granulosus glutamate receptor 2 0.0044 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.3131 0.3151 0.3151
Brugia malayi CHD4 protein 0.0059 0.0041 0.0096
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0024 0.0005 0.003
Echinococcus granulosus histone lysine methyltransferase setb 0.0407 0.0394 0.0404
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0095 0.0077 0.0079
Echinococcus granulosus cyclin k 0.002 0.0001 0.0001
Trichomonas vaginalis cyclin B, putative 0.0083 0.0065 0.0239
Leishmania major histone deacetylase, putative 0.1545 0.1546 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0143 0.0126 0.013
Echinococcus granulosus epidermal growth factor receptor 0.0147 0.013 0.0133
Loa Loa (eye worm) hypothetical protein 0.0136 0.0119 0.0376
Onchocerca volvulus 0.0371 0.0357 0.131
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Brugia malayi Calcitonin receptor-like protein seb-1 0.1471 0.147 0.3433
Brugia malayi mothers against decapentaplegic homolog 3 0.006 0.0042 0.0097
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0001 0.0001
Loa Loa (eye worm) thioredoxin reductase 0.0175 0.0159 0.0504
Giardia lamblia NADH oxidase lateral transfer candidate 0.0061 0.0043 0.0268
Loa Loa (eye worm) hypothetical protein 0.0128 0.0111 0.0351
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0143 0.0126 0.0125
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0056 0.0038 0.0119
Schistosoma mansoni axis inhibition protein axin 0.0026 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Brugia malayi ecdysteroid receptor 0.0143 0.0126 0.0295
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.009 0.0072 0.0458
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0075 0.0057 0.0363
Schistosoma mansoni myst histone acetyltransferase 0.0019 0.0001 0.0001
Echinococcus multilocularis expressed conserved protein 0.0177 0.016 0.016
Schistosoma mansoni thyroid hormone receptor 0.0297 0.0282 0.0289
Schistosoma mansoni Cyclin fold protein 0.002 0.0001 0.0001
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0024 0.0005 0.003
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Trichomonas vaginalis maltase-glucoamylase, putative 0.0046 0.0028 0.0102
Onchocerca volvulus 0.0371 0.0357 0.131
Brugia malayi hypothetical protein 0.0026 0.0007 0.0017
Giardia lamblia NADPH oxidoreductase, putative 0.0065 0.0047 0.0293
Onchocerca volvulus 0.0371 0.0357 0.131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Loa Loa (eye worm) hypothetical protein 0.0521 0.0509 0.1615
Schistosoma mansoni gliotactin 0.0062 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0407 0.0394 0.1249
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trichomonas vaginalis cyclins, putative 0.016 0.0143 0.0526
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni hypothetical protein 0.0105 0.0087 0.009
Entamoeba histolytica Ran family GTPase 0.0069 0.0051 0.0331
Entamoeba histolytica hypothetical protein 0.0322 0.0308 0.199
Entamoeba histolytica protein kinase, putative 0.0172 0.0155 0.1003
Echinococcus multilocularis Niemann Pick C1 protein 0.0269 0.0254 0.0253
Loa Loa (eye worm) RGC/RGC protein kinase 0.0037 0.0019 0.006
Echinococcus multilocularis epidermal growth factor receptor 0.0099 0.0082 0.0081
Entamoeba histolytica cell division protein kinase 2, putative 0.0193 0.0177 0.1144
Trypanosoma brucei importin beta-1 subunit, putative 0.0125 0.0108 0.0693
Brugia malayi Tyrosine-protein kinase abl-1 0.009 0.0073 0.0169
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0001 0.0004
Echinococcus granulosus L aminoadipate semialdehyde 0.0041 0.0023 0.0023
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0132 0.0115 0.0736
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0128 0.0111 0.011
Onchocerca volvulus 0.0028 0.0009 0.0034
Echinococcus multilocularis protein dispatched 1 0.0092 0.0075 0.0074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0143 0.0126 0.0295
Brugia malayi CHE-14 protein 0.0081 0.0063 0.0147
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0465 0.0452 0.0464
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0025 0.0006 0.0034
Giardia lamblia Fructose-bisphosphate aldolase 0.1331 0.1329 0.8599
Plasmodium vivax amine transporter, putative 0.0095 0.0077 0.0494
Schistosoma mansoni malate dehydrogenase 0.0024 0.0005 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.002 0.0001 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0077 0.0059 0.0188
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0068 0.005 0.0049
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0065 0.0047 0.0171
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0371 0.0357 0.0356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Echinococcus multilocularis biogenic amine (5HT) receptor 0.2643 0.2657 0.2656
Trichomonas vaginalis cyclin A, putative 0.002 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0031 0.0098
Plasmodium falciparum protein kinase 5 0.0193 0.0177 0.1139
Toxoplasma gondii histone deacetylase HDAC1 0.088 0.0872 0.5639
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0062 0.0044 0.0044
Brugia malayi Protein kinase domain containing protein 0.0054 0.0035 0.0083
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0227 0.0211 0.0216
Echinococcus granulosus g protein coupled receptor 0.0371 0.0357 0.0366
Schistosoma mansoni thyroid hormone receptor 0.0297 0.0282 0.0289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Echinococcus granulosus mothers against decapentaplegic 5 0.0133 0.0116 0.0119
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0039 0.0021 0.0048
Brugia malayi Glycosyl hydrolases family 31 protein 0.0046 0.0028 0.0065
Leishmania major cathepsin L-like protease 0.0106 0.0088 0.0562
Loa Loa (eye worm) jmjC domain-containing protein 0.0301 0.0286 0.0907
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.004 0.0022 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0095 0.0348
Schistosoma mansoni metabotropic glutamate receptor 0.0245 0.0229 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Mycobacterium ulcerans Type I modular polyketide synthase 0.0049 0.0031 0.0458
Schistosoma mansoni acetylcholinesterase 0.0062 0.0044 0.0045
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0094 0.0077 0.0079
Trichomonas vaginalis histone deacetylase, putative 0.1545 0.1546 0.5677
Loa Loa (eye worm) hypothetical protein 0.0109 0.0091 0.0289
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0001 0.0002
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.002 0.0001 0.0004
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.008 0.0062 0.0468
Loa Loa (eye worm) CXXC zinc finger family protein 0.0219 0.0203 0.0644
Echinococcus granulosus allatostatin A receptor 0.0371 0.0357 0.0366
Echinococcus multilocularis microtubule associated protein 2 0.9639 0.9741 0.9741
Loa Loa (eye worm) melatonin receptor type 1A 0.0371 0.0357 0.1132
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.002 0.0001 0.0003
Echinococcus multilocularis lamin 0.0077 0.0059 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0001 0.0002
Schistosoma mansoni histone deacetylase 0.1545 0.1546 0.1587
Trypanosoma cruzi cyclin, putative 0.016 0.0143 0.0922
Brugia malayi G-protein coupled receptor 0.0371 0.0357 0.0833
Echinococcus granulosus jumonji domain containing protein 0.0253 0.0237 0.0243
Loa Loa (eye worm) hypothetical protein 0.0844 0.0835 0.2651
Echinococcus granulosus malate dehydrogenase 0.0024 0.0005 0.0006
Trypanosoma brucei protein kinase, putative 0.0172 0.0155 0.0998
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Schistosoma mansoni ran 0.0069 0.0051 0.0052
Echinococcus granulosus tyrosine protein kinase Lyn 0.0022 0.0004 0.0004
Brugia malayi Fli-1 protein 0.0141 0.0124 0.0289
Echinococcus granulosus malate dehydrogenase 0.0024 0.0005 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0445 0.0431 0.6736
Onchocerca volvulus 0.0844 0.0835 0.3068
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0245 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0052 0.0034 0.0249
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0033 0.0014 0.0045
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0073 0.0055 0.0349
Schistosoma mansoni hypothetical protein 0.0182 0.0165 0.0169
Brugia malayi Ets-domain containing protein 0.0046 0.0028 0.0066
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Leishmania major cathepsin L-like protease 0.0028 0.0009 0.0051
Echinococcus multilocularis histone deacetylase 6 0.088 0.0872 0.0871
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.004 0.0258
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.004 0.0252
Echinococcus multilocularis conserved hypothetical protein 0.0787 0.0778 0.0777
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0033 0.0014 0.0013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 0.1712
Mycobacterium tuberculosis Carboxylesterase LipT 0.0062 0.0044 0.0325
Echinococcus granulosus mothers against decapentaplegic 6 0.006 0.0042 0.0043
Giardia lamblia Histone deacetylase 0.1545 0.1546 1
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Onchocerca volvulus 0.0637 0.0626 0.23
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Onchocerca volvulus 0.0068 0.005 0.0182
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.009 0.0072 0.0462
Echinococcus granulosus Niemann Pick C1 protein 0.0188 0.0172 0.0177
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.0077 0.0079
Schistosoma mansoni smad 0.0133 0.0116 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0044 0.0046
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.3131 0.3151 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0143 0.0126 0.0125
Plasmodium falciparum importin beta, putative 0.0125 0.0108 0.0693
Plasmodium vivax histone deacetylase, putative 0.0562 0.0551 0.3559
Echinococcus multilocularis translational activator gcn1 0.0024 0.0005 0.0004
Onchocerca volvulus 0.0371 0.0357 0.131
Schistosoma mansoni nuclear hormone receptor 0.0068 0.005 0.0051
Echinococcus multilocularis dro:myosuppressin receptor 0.0371 0.0357 0.0356
Echinococcus granulosus aryl hydrocarbon receptor 0.0056 0.0038 0.0039
Trichomonas vaginalis importin beta-1, putative 0.0101 0.0084 0.0308
Leishmania major cathepsin L-like protease 0.0028 0.0009 0.0051
Echinococcus multilocularis geminin 0.4655 0.4695 0.4694
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.002 0.0001 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.0371 0.0357 0.0366
Echinococcus granulosus histone deacetylase 6 0.088 0.0872 0.0895
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.004 0.0126
Toxoplasma gondii histone deacetylase HDAC4 0.0562 0.0551 0.3559
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Schistosoma mansoni hypothetical protein 0.0055 0.0037 0.0038
Trichomonas vaginalis penicillin-binding protein, putative 0.0205 0.0189 0.0694
Echinococcus multilocularis dnaJ subfamily B 0.2847 0.2864 0.2863
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0007 0.0007
Echinococcus multilocularis neuropeptides capa receptor 0.0371 0.0357 0.0356
Loa Loa (eye worm) heterochromatin protein 1 0.0242 0.0226 0.0718
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0126 0.0109 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0005 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Plasmodium falciparum histone deacetylase 2 0.088 0.0872 0.5639
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0371 0.0357 0.0356
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0271
Loa Loa (eye worm) hypothetical protein 0.0049 0.0031 0.0098
Leishmania major cathepsin L-like protease 0.0028 0.0009 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0211 0.0195 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0097 0.01
Echinococcus multilocularis histone deacetylase 1 0.1545 0.1546 0.1545
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Echinococcus granulosus Nuclear hormone receptor HR96 0.0068 0.005 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0088 0.0565
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0143 0.0126 0.0295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0035 0.0017 0.0119
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0086
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0115 0.0097 0.0625
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0094 0.0077 0.0076
Loa Loa (eye worm) histone deacetylase 3 0.1545 0.1546 0.4904
Loa Loa (eye worm) hypothetical protein 0.0047 0.0029 0.0091
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Trypanosoma brucei hypothetical protein, conserved 0.0205 0.0189 0.1217
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0052 0.0034 0.0506
Schistosoma mansoni neuropeptide F-like receptor 0.0371 0.0357 0.0366
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0009 0.0022
Giardia lamblia Kinase, CMGC CDK 0.0193 0.0177 0.1136
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0001 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.0054 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Brugia malayi Nuclear hormone receptor E75 0.0068 0.005 0.0116
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0055 0.0037 0.0038
Echinococcus granulosus cyclins 0.0083 0.0065 0.0067
Schistosoma mansoni sodium/chloride dependent transporter 0.0108 0.0091 0.0093
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0008 0.0008
Schistosoma mansoni histamine h1 receptor 0.0371 0.0357 0.0366
Echinococcus multilocularis neuropeptide receptor A26 0.06 0.0588 0.0587
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.002 0.0001 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0033 0.0014 0.0033
Toxoplasma gondii hypothetical protein 0.0044 0.0026 0.0161
Trypanosoma cruzi histone deacetylase 1, putative 0.1545 0.1546 1
Loa Loa (eye worm) hypothetical protein 0.0317 0.0302 0.096
Echinococcus multilocularis neutral alpha glucosidase AB 0.0046 0.0028 0.0027
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0371 0.0357 0.0366
Mycobacterium ulcerans error-prone DNA polymerase 0.0102 0.0084 0.1298
Schistosoma mansoni smad1 5 8 and 0.0133 0.0116 0.0119
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0371 0.0357 0.0366
Trypanosoma brucei cyclin 3 0.002 0.0001 0.0004
Trichomonas vaginalis Heterochromatin protein, putative 0.004 0.0021 0.0078
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0055 0.0037 0.0116
Schistosoma mansoni hypothetical protein 0.0078 0.006 0.0062
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0049 0.0031 0.0073
Echinococcus granulosus cyclin G2 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0205 0.0189 0.1436
Echinococcus granulosus g protein coupled receptor 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trichomonas vaginalis chromobox protein, putative 0.0146 0.0129 0.0474
Brugia malayi Probable ClpP-like protease 0.0128 0.0111 0.0258
Trichomonas vaginalis histone deacetylase, putative 0.1545 0.1546 0.5677
Echinococcus multilocularis Cyclin L1 0.002 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.0189 0.0694
Toxoplasma gondii SWI2/SNF2-containing PHD finger protein 0.0019 0.0001 0.000000000065333
Brugia malayi Cyclin, N-terminal domain containing protein 0.0256 0.024 0.0561
Echinococcus granulosus neuroligin 0.0062 0.0044 0.0045
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.004 0.0146
Echinococcus granulosus cyclins 0.0083 0.0065 0.0067
Schistosoma mansoni gabp alpha 0.0046 0.0028 0.0029
Loa Loa (eye worm) RecQ helicase 0.0024 0.0006 0.0018
Echinococcus granulosus expressed conserved protein 0.0177 0.016 0.0165
Loa Loa (eye worm) hypothetical protein 0.0082 0.0064 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0052 0.0034 0.0506
Echinococcus granulosus cyclin dependent kinase 0.0193 0.0177 0.0181
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0009 0.006
Echinococcus multilocularis malate dehydrogenase 0.0024 0.0005 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0143 0.0126 0.0125
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0199 0.0182 0.1386
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Loa Loa (eye worm) hypothetical protein 0.0365 0.0351 0.1114
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0133 0.0116 0.0119
Loa Loa (eye worm) hypothetical protein 0.0039 0.002 0.0065
Mycobacterium ulcerans Type I modular polyketide synthase 0.0049 0.0031 0.0458
Plasmodium falciparum transportin 0.0024 0.0005 0.0028
Echinococcus granulosus cyclins 0.0083 0.0065 0.0067
Brugia malayi nuclear hormone receptor 0.0143 0.0126 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0001 0.0005
Echinococcus multilocularis epidermal growth factor receptor 0.0147 0.013 0.0129
Mycobacterium tuberculosis Probable lipase LipD 0.0205 0.0189 0.1436
Schistosoma mansoni cellular tumor antigen P53 0.0137 0.0119 0.0123
Trypanosoma cruzi histone deacetylase, putative 0.088 0.0872 0.5639
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0055
Loa Loa (eye worm) hypothetical protein 0.0076 0.0058 0.0184
Entamoeba histolytica protein kinase domain containing protein 0.0172 0.0155 0.1003
Brugia malayi Dopamine receptor protein 2 0.0371 0.0357 0.0833
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0076 0.0058 0.0059
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.004 0.0021 0.002
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0193 0.0177 0.0561
Loa Loa (eye worm) hypothetical protein 0.0076 0.0058 0.0184
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0032 0.0013 0.008
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0172 0.0155 0.0492
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0115 0.0098 0.0628
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.04 0.0386 0.2945
Onchocerca volvulus Bile acid receptor homolog 0.0143 0.0126 0.0464
Onchocerca volvulus 0.0371 0.0357 0.131
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.002 0.0001 0.0001
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0095 0.0077 0.6651
Brugia malayi ImpB/MucB/SamB family protein 0.0055 0.0037 0.0086
Echinococcus granulosus kinesin family 1 0.0121 0.0103 0.0106
Entamoeba histolytica hypothetical protein 0.0101 0.0084 0.0543
Brugia malayi Intermediate filament tail domain containing protein 0.0077 0.0059 0.0138
Trichomonas vaginalis cyclins, putative 0.016 0.0143 0.0526
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Schistosoma mansoni ran 0.0069 0.0051 0.0052
Echinococcus multilocularis Polycystic kidney disease protein 0.0047 0.0029 0.0028
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.008 0.0062 0.0955
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0099 0.0082 0.0084
Loa Loa (eye worm) acetylcholinesterase 1 0.0365 0.0351 0.1114
Loa Loa (eye worm) norepinephrine transporter 0.0558 0.0547 0.1735
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 0.1712
Echinococcus multilocularis sterol regulatory element binding protein 0.0081 0.0063 0.0062
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0132 0.0115 0.0114
Trichomonas vaginalis cyclins, putative 0.002 0.0001 0.0005
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.016 0.0143 0.0919
Echinococcus multilocularis cyclin dependent kinase 0.0193 0.0177 0.0176
Loa Loa (eye worm) glutamate receptor 0.0112 0.0095 0.0301
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0006 0.0031
Entamoeba histolytica hypothetical protein 0.004 0.0021 0.0138
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Toxoplasma gondii hypothetical protein 0.0031 0.0012 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Brugia malayi Carboxylesterase family protein 0.0062 0.0044 0.0102
Trypanosoma cruzi histone deacetylase, putative 0.0562 0.0551 0.3559
Echinococcus granulosus metabotropic glutamate receptor 2 0.0245 0.0229 0.0236
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Echinococcus granulosus G protein coupled receptor 139 0.0371 0.0357 0.0366
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.004 0.0039
Schistosoma mansoni retinoic acid receptor RXR 0.0143 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0257 0.0241 0.0765
Echinococcus granulosus Zinc finger DBF type 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0205 0.0189 0.1436
Trichomonas vaginalis chromobox protein, putative 0.0146 0.0129 0.0474
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Trichomonas vaginalis inositol monophosphatase, putative 0.0115 0.0098 0.036
Brugia malayi F/Y-rich N-terminus family protein 0.0146 0.0129 0.0301
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0089 0.0072 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0068 0.005 0.0051
Trypanosoma brucei ISWI complex protein 0.0023 0.0005 0.0023
Schistosoma mansoni myst-related protein 0.0033 0.0014 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0371 0.0357 0.0366
Brugia malayi tailless protein 0.0068 0.005 0.0116
Onchocerca volvulus 0.0106 0.0089 0.0326
Echinococcus multilocularis importin 5 0.0024 0.0005 0.0004
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0024 0.0006 0.003
Entamoeba histolytica hypothetical protein 0.0026 0.0007 0.0047
Schistosoma mansoni hypothetical protein 0.0047 0.0029 0.0029
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0069 0.0051 0.0325
Trypanosoma cruzi cyclin 9, putative 0.002 0.0001 0.0004
Brugia malayi Nuclear hormone receptor E75 0.0068 0.005 0.0116
Loa Loa (eye worm) latrophilin receptor protein 2 0.0465 0.0452 0.1436
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0407 0.0394 0.0404
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0032 0.0103
Loa Loa (eye worm) PHD-finger family protein 0.0075 0.0057 0.0181
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni hypothetical protein 0.1335 0.1333 0.1369
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0045 0.0026 0.0062
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0143 0.0126 0.0125
Entamoeba histolytica cyclin family protein 0.0083 0.0065 0.0421
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0049 0.0031 0.0197
Brugia malayi hypothetical protein 0.0102 0.0084 0.0197
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0006 0.003
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 1
Schistosoma mansoni amine GPCR 0.0371 0.0357 0.0366
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0075 0.0057 0.0365
Onchocerca volvulus 0.0095 0.0077 0.0284
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0407 0.0394 0.0404
Echinococcus multilocularis neuropeptide Y receptor 0.0371 0.0357 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.054 0.1985
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0006 0.0005
Loa Loa (eye worm) G-protein coupled receptor 0.0371 0.0357 0.1132
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Echinococcus granulosus translational activator gcn1 0.0024 0.0005 0.0005
Onchocerca volvulus 0.0385 0.0371 0.1363
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.004 0.0146
Brugia malayi TspO/MBR family protein 0.0637 0.0626 0.1462
Echinococcus multilocularis importin subunit beta 1 0.0125 0.0108 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0032 0.0014 0.0195
Trypanosoma cruzi cysteine peptidase, putative 0.0106 0.0088 0.0565
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0061 0.0043 0.01
Trichomonas vaginalis ran, putative 0.0069 0.0051 0.0188
Plasmodium vivax hypothetical protein, conserved 0.002 0.0001 0.0004
Echinococcus granulosus axis inhibition protein axin 0.0026 0.0007 0.0007
Echinococcus multilocularis hypothetical protein 0.0049 0.0031 0.003
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Trypanosoma brucei protein kinase, putative 0.0046 0.0028 0.0175
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0271
Brugia malayi Associated with TFs and helicases family protein 0.004 0.0021 0.005
Brugia malayi nuclear receptor NHR-88 0.0143 0.0126 0.0295
Echinococcus granulosus acetylcholinesterase 0.0365 0.0351 0.036
Schistosoma mansoni tyrosine kinase 0.0095 0.0077 0.0079
Onchocerca volvulus 0.0371 0.0357 0.131
Loa Loa (eye worm) hypothetical protein 0.0365 0.0351 0.1114
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0102 0.0085 0.064
Schistosoma mansoni RAR-like nuclear receptor 0.0143 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Plasmodium vivax histone deacetylase, putative 0.088 0.0872 0.5639
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0067 0.0049 0.0048
Schistosoma mansoni rab6-interacting 0.0047 0.0029 0.0029
Echinococcus granulosus mixed lineage leukemia protein mll 0.0067 0.0049 0.005
Brugia malayi Metabotropic glutamate receptor precursor. 0.0292 0.0276 0.0645
Echinococcus granulosus ecdysone induced protein 78C 0.0143 0.0126 0.013
Brugia malayi Protein kinase domain containing protein 0.0126 0.0109 0.0254
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0143 0.0126 0.0401
Echinococcus granulosus cyclin A3 4 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.0029 0.0091
Trichomonas vaginalis histone deacetylase, putative 0.1545 0.1546 0.5677
Echinococcus multilocularis histone deacetylase 6 0.088 0.0872 0.0871
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0133 0.0116 0.0115
Echinococcus granulosus phd:f box containing protein 0.0075 0.0057 0.0059
Loa Loa (eye worm) hypothetical protein 0.0158 0.0141 0.0448
Onchocerca volvulus Protein CNPPD1 homolog 0.002 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0562 0.0551 0.1747
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0006 0.0027
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0006 0.0021
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0001 0.0004
Echinococcus granulosus chromobox protein 1 0.0242 0.0226 0.0232
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Trypanosoma brucei histone deacetylase 3 0.088 0.0872 0.5639
Brugia malayi Isocitrate dehydrogenase 0.0024 0.0006 0.0013
Onchocerca volvulus 0.0095 0.0077 0.0284
Plasmodium falciparum ataxin-2 like protein, putative 0.0158 0.0141 0.0907
Schistosoma mansoni neuropeptide receptor 0.0371 0.0357 0.0366
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0068 0.005 0.0051
Mycobacterium leprae Probable polyketide synthase Pks1 0.0052 0.0034 0.0506
Toxoplasma gondii hypothetical protein 0.0063 0.0045 0.0285
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0143 0.0126 0.013
Schistosoma mansoni tyrosine kinase 0.0095 0.0077 0.0079
Trypanosoma brucei cyclin 9 0.002 0.0001 0.0004
Loa Loa (eye worm) fli-1 protein 0.0141 0.0124 0.0392
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0029 0.0011 0.0146
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0128 0.0111 0.0711
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0531 0.0519 0.0518
Schistosoma mansoni microtubule-associated protein tau 0.9639 0.9741 1
Trypanosoma brucei cdc2-related kinase 1 0.0193 0.0177 0.1139
Entamoeba histolytica hypothetical protein 0.0322 0.0308 0.199
Schistosoma mansoni ap endonuclease 0.0058 0.004 0.0041
Trichomonas vaginalis cyclin D, putative 0.0083 0.0065 0.0239
Loa Loa (eye worm) nuclear hormone receptor 0.0068 0.005 0.0158
Mycobacterium tuberculosis Probable esterase LipL 0.0205 0.0189 0.1436
Schistosoma mansoni hypothetical protein 0.2847 0.2864 0.294
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0046 0.0028 0.018
Loa Loa (eye worm) hypothetical protein 0.0173 0.0156 0.0495
Loa Loa (eye worm) intermediate filament protein 0.0077 0.0059 0.0188
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0068 0.005 0.0049
Mycobacterium tuberculosis Probable reductase 0.04 0.0386 0.2945
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Loa Loa (eye worm) cyclin C 0.002 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0023
Schistosoma mansoni hypothetical protein 0.0078 0.006 0.0062
Loa Loa (eye worm) RGC/RGC protein kinase 0.0037 0.0019 0.006
Trypanosoma brucei histone deacetylase 1 0.1545 0.1546 1
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0024 0.0005 0.003
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0049 0.0031 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0052 0.0034 0.0249
Trypanosoma brucei unspecified product 0.0038 0.0019 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Echinococcus granulosus cyclin dependent kinase 5 0.0193 0.0177 0.0181
Loa Loa (eye worm) CYL-1 protein 0.002 0.0001 0.0005
Onchocerca volvulus 0.0371 0.0357 0.131
Plasmodium falciparum cyclin 0.0083 0.0065 0.0416
Treponema pallidum fructose-bisphosphate aldolase 0.1331 0.1329 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Trichomonas vaginalis mercuric reductase, putative 0.0061 0.0043 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0143 0.0126 0.0295
Onchocerca volvulus 0.0172 0.0155 0.0569
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0046 0.0028 0.0175
Trichomonas vaginalis glucosylceramidase, putative 0.0382 0.0368 0.1351
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Echinococcus multilocularis Smad4 0.0133 0.0116 0.0115
Schistosoma mansoni coup transcription factor 0.0143 0.0126 0.013
Echinococcus granulosus peptidase Clp S14 family 0.0084 0.0066 0.0068
Loa Loa (eye worm) raf kinase 0.0021 0.0003 0.0009
Loa Loa (eye worm) MH2 domain-containing protein 0.006 0.0042 0.0132
Loa Loa (eye worm) glutaminase 0.0175 0.0159 0.0504
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0049 0.0031 0.0099
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0371 0.0357 0.0356
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Schistosoma mansoni protein kinase 0.0037 0.0019 0.0019
Onchocerca volvulus 0.0062 0.0044 0.0161
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Onchocerca volvulus 0.0371 0.0357 0.131
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.0245
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.2002 0.2008 0.2061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0335 0.0321 0.0329
Loa Loa (eye worm) helicase 0.004 0.0021 0.0068
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0143 0.0126 0.0295
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0076 0.0058 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0143 0.0126 0.0295
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0115 0.0097 0.0625
Brugia malayi orphan nuclear receptor NR2E1 0.0068 0.005 0.0116
Loa Loa (eye worm) hypothetical protein 0.0139 0.0122 0.0388
Echinococcus granulosus neuropeptide FF receptor 2 0.0371 0.0357 0.0366
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0552 0.054 0.1262
Brugia malayi Cathepsin L-like precursor 0.0028 0.0009 0.0022
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0021 0.0067
Echinococcus multilocularis jumonji domain containing protein 0.0253 0.0237 0.0236
Giardia lamblia PHD finger protein 15 0.0182 0.0165 0.106
Echinococcus multilocularis lysine specific demethylase 6a 0.0075 0.0057 0.0056
Loa Loa (eye worm) hypothetical protein 0.0079 0.0061 0.0194
Brugia malayi hypothetical protein 0.0068 0.005 0.0116
Echinococcus granulosus PHD finger protein rhinoceros 0.0182 0.0165 0.0169
Giardia lamblia NADPH oxidoreductase, putative 0.0065 0.0047 0.0293
Echinococcus granulosus neuropeptide Y receptor 0.0371 0.0357 0.0366
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0371 0.0357 0.0366
Echinococcus multilocularis cysteine protease 0.0028 0.0009 0.0008
Brugia malayi SET domain containing protein 0.0057 0.0039 0.0091
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Plasmodium falciparum histone acetyltransferase GCN5 0.0061 0.0043 0.027
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus multilocularis receptor type guanylyl cyclase 0.0037 0.0019 0.0018
Schistosoma mansoni chromobox protein 0.004 0.0021 0.0022
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.013 0.0113 0.0112
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0371 0.0357 0.0356
Brugia malayi Steroid receptor seven-up type 2 0.0143 0.0126 0.0295
Onchocerca volvulus 0.0371 0.0357 0.131
Brugia malayi PHD-finger family protein 0.0079 0.0061 0.0142
Schistosoma mansoni hypothetical protein 0.1005 0.0999 0.1026
Brugia malayi regulator of G-protein signaling egl-10 0.0026 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0846 0.0838 0.2659
Echinococcus multilocularis nuclear factor of activated T cells 5 0.009 0.0072 0.0071
Brugia malayi hypothetical protein 0.0039 0.002 0.0048
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0046 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Trichomonas vaginalis cyclin B3, putative 0.002 0.0001 0.0005
Schistosoma mansoni cpg binding protein 0.0219 0.0203 0.0208
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.0077 0.0079
Entamoeba histolytica serine/threonine protein kinase, putative 0.0132 0.0115 0.0744
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0059 0.0041 0.0042
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.004 0.0021 0.0022
Loa Loa (eye worm) TAR-binding protein 0.0211 0.0195 0.0619
Echinococcus multilocularis phd:f box containing protein 0.0075 0.0057 0.0056
Toxoplasma gondii NADPH-glutathione reductase 0.0061 0.0043 0.0271
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0069 0.0051 0.0322
Brugia malayi G-protein coupled receptor 0.0371 0.0357 0.0833
Schistosoma mansoni lamin 0.0077 0.0059 0.0061
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Entamoeba histolytica cyclin, domain containing protein 0.002 0.0001 0.0009
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0059 0.0041 0.0262
Brugia malayi Bromodomain containing protein 0.0196 0.0179 0.0419
Brugia malayi PHD-finger family protein 0.0019 0.0001 0.0002
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.004 0.0021 0.0132
Echinococcus multilocularis cyclin A3 4 0.002 0.0001 0.0001
Echinococcus multilocularis snurportin 1 0.1335 0.1333 0.1332
Schistosoma mansoni biogenic amine receptor 0.0371 0.0357 0.0366
Schistosoma mansoni tyrosine kinase 0.0099 0.0082 0.0084
Schistosoma mansoni hypothetical protein 0.0322 0.0308 0.0316
Brugia malayi PXA domain containing protein 0.0026 0.0007 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0442 0.0428 0.2768
Brugia malayi RNA, U transporter 1 0.0356 0.0341 0.0797
Echinococcus granulosus cyclin y 0.002 0.0001 0.0001
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.0009 0.0008
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0028 0.0009 0.0054
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0086
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0143 0.0126 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Schistosoma mansoni smad1 5 8 and 0.0133 0.0116 0.0119
Trypanosoma cruzi polo-like protein kinase, putative 0.0132 0.0115 0.0739
Brugia malayi Serotonin/octopamine receptor family protein 7 0.2002 0.2008 0.4689
Echinococcus granulosus tumor protein p63 0.0933 0.0926 0.095
Trichomonas vaginalis CAMK family protein kinase 0.0072 0.0054 0.0199
Schistosoma mansoni lipoxygenase 0.0169 0.0153 0.0157
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0029
Toxoplasma gondii hypothetical protein 0.002 0.0001 0.0004
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0075 0.0057 0.0363
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.065 0.064 0.4885
Loa Loa (eye worm) Smad1 0.0133 0.0116 0.0369
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Brugia malayi hypothetical protein 0.0062 0.0044 0.0102
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0096 0.0079 0.0505
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Leishmania major malate dehydrogenase 0.0024 0.0005 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0044 0.0046
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0371 0.0357 0.0833
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0371 0.0357 0.0356
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0062 0.0044 0.0045
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0531 0.0519 0.0533
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0371 0.0357 0.0366
Schistosoma mansoni eyes absent homolog 0.0045 0.0027 0.0028
Echinococcus multilocularis smad 0.0133 0.0116 0.0115
Toxoplasma gondii histone deacetylase HDAC5 0.0562 0.0551 0.356
Trypanosoma cruzi histone deacetylase 1, putative 0.1545 0.1546 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0281 0.0266 0.0265
Onchocerca volvulus Huntingtin homolog 0.0167 0.0151 0.0553
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus tachykinin peptides receptor 99D 0.0371 0.0357 0.0366
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0193 0.0177 0.1139
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.004 0.0252
Schistosoma mansoni hypothetical protein 0.0465 0.0452 0.0464
Echinococcus granulosus histone deacetylase 7 0.088 0.0872 0.0895
Brugia malayi Dopamine receptor 0.0371 0.0357 0.0833
Trypanosoma cruzi cdc2-related kinase 3 0.0193 0.0177 0.1139
Echinococcus granulosus RUN 0.0047 0.0029 0.0029
Schistosoma mansoni inositol monophosphatase 0.0115 0.0098 0.0101
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1545 0.1546 0.5677
Echinococcus multilocularis thyroid hormone receptor alpha 0.0297 0.0282 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Trichomonas vaginalis cyclin B, putative 0.002 0.0001 0.0005
Onchocerca volvulus 0.0019 0.0001 0.0003
Leishmania major protein kinase, putative 0.003 0.0012 0.0067
Mycobacterium ulcerans polyketide synthase 0.0052 0.0034 0.0506
Echinococcus granulosus cpg binding protein 0.0238 0.0223 0.0229
Loa Loa (eye worm) MH2 domain-containing protein 0.0133 0.0116 0.0369
Echinococcus granulosus tm gpcr rhodopsin 0.5098 0.5143 0.528
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0073 0.0055 0.0412
Trichomonas vaginalis cyclin B, putative 0.016 0.0143 0.0526
Trichomonas vaginalis histone deacetylase, putative 0.1545 0.1546 0.5677
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0136 0.0119 0.0435
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0043 0.0271
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0012 0.007
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.0245
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0371 0.0357 0.0366
Toxoplasma gondii PHD-finger domain-containing protein 0.0182 0.0165 0.1063
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0069 0.0051 0.0325
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.004 0.0249
Echinococcus multilocularis histone deacetylase 8 0.0562 0.0551 0.055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0001 0.0000072158
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0006 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0001 0.0005
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.065 0.064 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0061 0.0043 0.0647
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0012 0.007
Trichomonas vaginalis cyclin B3, putative 0.002 0.0001 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0365 0.0351 0.036
Schistosoma mansoni metabotropic glutamate receptor 0.0145 0.0128 0.0132
Echinococcus granulosus histone acetyltransferase myst4 0.0019 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.005 0.0032 0.0075
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.0026 0.0025
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0193 0.0177 0.0181
Echinococcus granulosus methyl CpG binding domain protein 2 0.0062 0.0044 0.0045
Brugia malayi PHD-finger family protein 0.0108 0.0091 0.0212
Giardia lamblia Kinase, CMGC GSK 0.0172 0.0155 0.0995
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0345 0.0331 0.033
Brugia malayi SET domain containing protein 0.0037 0.0018 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0144 0.053
Loa Loa (eye worm) hypothetical protein 0.1536 0.1537 0.4877
Echinococcus granulosus snurportin 1 0.1335 0.1333 0.1369
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0046 0.0027 0.02
Onchocerca volvulus Histone deacetylase 10 homolog 0.0562 0.0551 0.2022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0335 0.0321 0.1017
Leishmania major histone deacetylase, putative 0.088 0.0872 0.5637
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0006 0.0018
Brugia malayi jmjC domain containing protein 0.0075 0.0057 0.0134
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0182 0.0165 0.0169
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0371 0.0357 0.0356
Brugia malayi Nuclear hormone receptor-like 1 0.0076 0.0058 0.0135
Loa Loa (eye worm) MH1 domain-containing protein 0.0133 0.0116 0.0369
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0062 0.0044 0.0044
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.0077 0.0079
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0084 0.0066 0.1013
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0078 0.0288
Brugia malayi AF-10 protein 0.0059 0.0041 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.054 0.1985
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0084 0.0066 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0049 0.0031 0.0032
Echinococcus multilocularis glutamate receptor 2 0.0044 0.0026 0.0025
Loa Loa (eye worm) acetyltransferase 0.0234 0.0218 0.0691
Loa Loa (eye worm) jmjC domain-containing protein 0.0375 0.0361 0.1145
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0006 0.0021
Trichomonas vaginalis cyclin D, putative 0.0083 0.0065 0.0239
Trichomonas vaginalis cyclin B3, putative 0.0083 0.0065 0.0239
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0205 0.0189 0.0194
Echinococcus multilocularis glutamate receptor 2 0.0033 0.0014 0.0013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0043 0.0268
Schistosoma mansoni neuropeptide receptor 0.0371 0.0357 0.0366
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0021 0.0022
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.002 0.0001 0.0003
Schistosoma mansoni peptidase 0.0019 0.0001 0.0001
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0028 0.0009 0.0029
Schistosoma mansoni histone deacetylase 1 2 3 0.0562 0.0551 0.0565
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0143 0.0126 0.0464
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0177 0.0649
Echinococcus granulosus transcription factor Dp 1 0.0029 0.001 0.001
Schistosoma mansoni cpg binding protein 0.0238 0.0223 0.0229
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0006 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.018
Echinococcus multilocularis dna polymerase eta 0.0055 0.0037 0.0036
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Plasmodium vivax cyclin 4, putative 0.002 0.0001 0.0004
Onchocerca volvulus 0.0637 0.0626 0.23
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0079 0.0061 0.0194
Loa Loa (eye worm) glutamate receptor 0.0292 0.0276 0.0877
Giardia lamblia Cyclin A 0.0083 0.0065 0.0412
Trichomonas vaginalis cyclin A, putative 0.016 0.0143 0.0526
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Plasmodium falciparum glycogen synthase kinase 3 0.0172 0.0155 0.0998
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Schistosoma mansoni polycystin 1-related 0.0047 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0023 0.0073
Echinococcus granulosus neuropeptide receptor A26 0.06 0.0588 0.0604
Brugia malayi AKH receptor 0.0371 0.0357 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0007 0.0027
Trypanosoma cruzi importin beta-1 subunit, putative 0.0101 0.0084 0.0538
Trichomonas vaginalis histone deacetylase, putative 0.1545 0.1546 0.5677
Entamoeba histolytica hypothetical protein 0.0115 0.0097 0.0631
Echinococcus multilocularis beta LACTamase domain containing family member 0.0205 0.0189 0.0188
Echinococcus granulosus histone acetyltransferase myst3 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0103 0.0086 0.0646
Brugia malayi acetyltransferase, GNAT family protein 0.0234 0.0218 0.0508
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0061 0.0043 0.0042
Echinococcus multilocularis JmjC domain containing protein 4 0.0075 0.0057 0.0056
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0039 0.0021 0.0306
Echinococcus multilocularis dual specificity 0.0115 0.0097 0.0097
Entamoeba histolytica protein kinase, putative 0.0115 0.0097 0.0631
Loa Loa (eye worm) neuropeptide F receptor 0.0371 0.0357 0.1132
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0143 0.0126 0.013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.0008 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0119 0.0102 0.0771
Schistosoma mansoni tar DNA-binding protein 0.0211 0.0195 0.02
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.004 0.0021 0.0138
Trypanosoma cruzi ISWI complex protein 0.0055 0.0037 0.0236
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.002 0.0001 0.0003
Brugia malayi hypothetical protein 0.0068 0.005 0.0116
Toxoplasma gondii aldehyde dehydrogenase 0.0199 0.0182 0.1175
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1331 0.1329 0.8601
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0126 0.0109 0.0112
Loa Loa (eye worm) histone deacetylase 7A 0.088 0.0872 0.2767
Onchocerca volvulus 0.0637 0.0626 0.23
Onchocerca volvulus Cyclin L homolog 0.002 0.0001 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0009 0.0027
Brugia malayi Protein cec-1. 0.004 0.0021 0.005
Leishmania major hypothetical protein, conserved 0.0075 0.0057 0.0361
Trypanosoma brucei ISWI complex protein 0.0055 0.0037 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0066 0.0048 0.0177
Toxoplasma gondii histone deacetylase HDAC2 0.1545 0.1546 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0001 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1311 0.1308 1
Schistosoma mansoni cyclin G2 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0143 0.0126 0.0401
Brugia malayi neuropeptide F receptor 0.0371 0.0357 0.0833
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0019 0.012
Loa Loa (eye worm) RGC/RGC protein kinase 0.0037 0.0019 0.006
Onchocerca volvulus 0.0019 0.0001 0.0003
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0046 0.0028 0.0174
Echinococcus granulosus lamin 0.0077 0.0059 0.0061
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0001 0.0005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0335 0.0321 0.032
Loa Loa (eye worm) hypothetical protein 0.0205 0.0189 0.06
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus granulosus somatostatin receptor 0.0371 0.0357 0.0366
Plasmodium vivax ataxin-2 like protein, putative 0.0158 0.0141 0.0907
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0062 0.0044 0.0046
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0037 0.0232
Onchocerca volvulus Cathepsin L homolog 0.0028 0.0009 0.0034
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Echinococcus granulosus histone acetyltransferase KAT2B 0.0075 0.0057 0.0058
Echinococcus granulosus neuropeptide Y receptor 0.0371 0.0357 0.0366
Entamoeba histolytica hypothetical protein 0.0322 0.0308 0.199
Echinococcus granulosus axis inhibition protein axin 0.0026 0.0007 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0014 0.0086
Brugia malayi Cathepsin L-like precursor 0.0028 0.0009 0.0022
Trypanosoma cruzi cdc2-related kinase 1 0.0193 0.0177 0.1139
Loa Loa (eye worm) histone deacetylase 0.088 0.0872 0.2767
Echinococcus multilocularis cyclin B 0.016 0.0143 0.0142
Brugia malayi MH1 domain containing protein 0.0074 0.0056 0.013
Brugia malayi MH2 domain containing protein 0.006 0.0042 0.0097
Loa Loa (eye worm) histone deacetylase 1 0.1545 0.1546 0.4904
Echinococcus multilocularis PHD finger protein rhinoceros 0.0182 0.0165 0.0164
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0026 0.0007 0.0007
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1545 0.1546 0.5677
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Leishmania major trypanothione reductase 0.0175 0.0159 0.1019
Echinococcus multilocularis transportin 1 0.0024 0.0005 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0055 0.0037 0.0118
Brugia malayi hypothetical protein 0.0095 0.0077 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0037 0.0019 0.0069
Mycobacterium ulcerans Type I modular polyketide synthase 0.0049 0.0031 0.0458
Brugia malayi Muscleblind-like protein 0.0081 0.0063 0.0148
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 0.0711
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0024 0.0006 0.003
Schistosoma mansoni axis inhibition protein axin 0.0026 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.016 0.0143 0.0455
Leishmania major mitochondrial DNA polymerase beta 0.019 0.0173 0.1114
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0075 0.0057 0.0365
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0169 0.0153 0.0152
Schistosoma mansoni histone deacetylase 4 5 0.088 0.0872 0.0895
Loa Loa (eye worm) hypothetical protein 0.0637 0.0626 0.1987
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0191 0.0175 0.018
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0001 0.0003
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0128 0.0111 0.0711
Brugia malayi ImpB/MucB/SamB family protein 0.0055 0.0037 0.0086
Brugia malayi nuclear receptor RXR 0.0068 0.005 0.0116
Loa Loa (eye worm) glutaminase 2 0.0175 0.0159 0.0504
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0143 0.0126 0.013
Onchocerca volvulus 0.0028 0.0009 0.0034
Toxoplasma gondii hypothetical protein 0.0095 0.0077 0.0494
Echinococcus multilocularis allatostatin A receptor 0.0371 0.0357 0.0356
Trypanosoma cruzi trypanothione reductase, putative 0.0175 0.0159 0.1022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0143 0.0126 0.0295
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0021 0.0078
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0153 0.0136 0.0135
Toxoplasma gondii cyclin dependent kinase binding protein 0.002 0.0001 0.0004
Echinococcus multilocularis insulin receptor 0.0126 0.0109 0.0108
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0558 0.0547 0.1276
Loa Loa (eye worm) hypothetical protein 0.0558 0.0547 0.1735
Echinococcus multilocularis raf serine:threonine protein kinase 0.0026 0.0007 0.0007
Plasmodium falciparum glutathione reductase 0.0175 0.0159 0.1022
Echinococcus granulosus neutral alpha glucosidase AB 0.0046 0.0028 0.0029
Trypanosoma cruzi histone deacetylase, putative 0.0562 0.0551 0.3559
Brugia malayi jmjC domain containing protein 0.0656 0.0646 0.1508
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0345 0.0331 0.2137
Plasmodium falciparum JmjC domain-containing protein, putative 0.0075 0.0057 0.0365
Echinococcus granulosus raf serine:threonine protein kinase 0.0026 0.0007 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0044 0.0046
Onchocerca volvulus Cathepsin L homolog 0.0028 0.0009 0.0034
Entamoeba histolytica HEAT repeat domain containing protein 0.0024 0.0005 0.0033
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0095 0.0077 0.0076
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0043 0.0409
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0115 0.0098 0.0634
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0065 0.0047 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0382 0.0368 0.1351
Schistosoma mansoni zinc finger protein 0.0019 0.0001 0.0001
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.002 0.0065
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0371 0.0357 0.0366
Echinococcus multilocularis neuropeptide Y receptor 0.0371 0.0357 0.0356
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.002 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0028 0.0009 0.006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0182 0.2834
Schistosoma mansoni cpg binding protein 0.0238 0.0223 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Trypanosoma brucei mitotic cyclin 6 0.016 0.0143 0.0922
Loa Loa (eye worm) hypothetical protein 0.0079 0.0061 0.0193
Leishmania major hypothetical protein, conserved 0.0205 0.0189 0.1214
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0076 0.0058 0.0059
Brugia malayi hypothetical protein 0.0047 0.0029 0.0067
Echinococcus granulosus Protein patched homolog 1 0.0081 0.0063 0.0065
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0371 0.0357 0.0356
Onchocerca volvulus 0.0055 0.0037 0.0137
Leishmania major hypothetical protein, conserved 0.0158 0.0141 0.0904
Schistosoma mansoni biogenic amine (5HT) receptor 0.0846 0.0838 0.086
Echinococcus multilocularis fmrfamide receptor 0.0371 0.0357 0.0356
Schistosoma mansoni alpha-glucosidase 0.0178 0.0162 0.0166
Schistosoma mansoni hypothetical protein 0.0075 0.0057 0.0059
Mycobacterium ulcerans beta-lactamase 0.0205 0.0189 0.2938
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.0637 0.0626 0.0643
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0112 0.0095 0.0097
Loa Loa (eye worm) hypothetical protein 0.0182 0.0165 0.0524
Plasmodium vivax hypothetical protein, conserved 0.004 0.0021 0.0132
Entamoeba histolytica cell division protein kinase 2, putative 0.0193 0.0177 0.1144
Onchocerca volvulus 0.0037 0.0018 0.0068
Echinococcus multilocularis fmrfamide receptor 0.0371 0.0357 0.0356
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Entamoeba histolytica acetyltransferase, GNAT family 0.0061 0.0043 0.0276
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Brugia malayi steroid hormone receptor 0.0143 0.0126 0.0295
Trichomonas vaginalis cyclin B, putative 0.016 0.0143 0.0526
Toxoplasma gondii HEAT repeat-containing protein 0.0125 0.0108 0.0693
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0061 0.0043 0.0044
Loa Loa (eye worm) RNA binding protein 0.0211 0.0195 0.0619
Schistosoma mansoni DNA helicase recq5 0.0024 0.0006 0.0006
Onchocerca volvulus Mothers against decapentaplegic homolog 0.006 0.0042 0.0152
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0301 0.0286 0.0293
Loa Loa (eye worm) hypothetical protein 0.0205 0.0189 0.06
Echinococcus multilocularis cyclin 0.002 0.0001 0.0001
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0069 0.0051 0.005
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0106 0.0089 0.0091
Echinococcus granulosus insulin receptor 0.0126 0.0109 0.0112
Echinococcus granulosus dro:myosuppressin receptor 0.0371 0.0357 0.0366
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0028 0.0009 0.0062
Schistosoma mansoni kinase 0.0074 0.0056 0.0057
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0069 0.0051 0.0162
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.04 0.0386 0.2945
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Brugia malayi larval opioid receptor 0.0371 0.0357 0.0833
Leishmania major histone deacetylase, putative 0.088 0.0872 0.5637
Echinococcus multilocularis cyclin dependent kinase 5 0.0193 0.0177 0.0176
Loa Loa (eye worm) hypothetical protein 0.0074 0.0056 0.0177
Loa Loa (eye worm) carboxylesterase 0.0062 0.0044 0.0139
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Loa Loa (eye worm) hypothetical protein 0.2002 0.2008 0.6372
Loa Loa (eye worm) acyl carrier protein 0.0022 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0037 0.0232
Onchocerca volvulus Protein cycle homolog 0.0039 0.0021 0.0076
Toxoplasma gondii exonuclease III APE 0.0058 0.004 0.0252
Brugia malayi serine/threonine-protein kinase plk-2 0.0132 0.0115 0.0269
Trypanosoma brucei C-8 sterol isomerase, putative 0.102 0.1014 0.6557
Brugia malayi Protein kinase domain containing protein 0.0115 0.0097 0.0228
Echinococcus granulosus receptor type guanylyl cyclase 0.0037 0.0019 0.0019
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0006 0.0031
Trichomonas vaginalis glutaminase, putative 0.0175 0.0159 0.0583
Trypanosoma cruzi cruzipain precursor, putative 0.0106 0.0088 0.0565
Onchocerca volvulus 0.024 0.0224 0.0823
Giardia lamblia Kinase, CMGC GSK 0.0172 0.0155 0.0995
Brugia malayi glutathione reductase 0.0175 0.0159 0.0371
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0039 0.0021 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0001 0.0002
Entamoeba histolytica histone deacetylase, putative 0.1545 0.1546 1
Echinococcus granulosus smad 0.0133 0.0116 0.0119
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0115 0.0098 0.82
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0235 0.0219 0.0218
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0193 0.0177 0.0561
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0143 0.0126 0.0295
Leishmania major cysteine peptidase A (CPA) 0.0028 0.0009 0.0051
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.005 0.0049
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0205 0.0189 0.0194
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0062 0.0044 0.0325
Trichomonas vaginalis cyclin D, putative 0.002 0.0001 0.0005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0039 0.0021 0.0306
Echinococcus multilocularis RUN 0.0047 0.0029 0.0028
Plasmodium falciparum transporter, putative 0.0095 0.0077 0.0494
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.002 0.0001 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0322 0.0308 0.0316
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0371 0.0357 0.0366
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0063 0.0232
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0089 0.0072 0.0263
Echinococcus multilocularis g protein coupled receptor 0.0371 0.0357 0.0356
Loa Loa (eye worm) hypothetical protein 0.0205 0.0189 0.06
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Loa Loa (eye worm) cyclin domain-containing protein 0.002 0.0001 0.0005
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0061 0.0043 0.0647
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.002 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Brugia malayi map kinase activated protein kinase protein 2 0.3131 0.3151 0.7358
Echinococcus granulosus nuclear receptor nhr 48 0.0068 0.005 0.0051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.006
Trypanosoma brucei trypanothione reductase 0.0175 0.0159 0.1022
Leishmania major mitochondrial malate dehydrogenase 0.0024 0.0005 0.0026
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.018 0.0163 0.0518
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0097 0.0631
Echinococcus granulosus serotonin receptor 0.0371 0.0357 0.0366
Echinococcus granulosus FTZ F1 alpha 0.0143 0.0126 0.013
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0061 0.0043 0.0271
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0143 0.0126 0.0295
Loa Loa (eye worm) hypothetical protein 0.0062 0.0044 0.0139
Echinococcus multilocularis carboxylesterase 5A 0.0365 0.0351 0.035
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0094 0.0077 0.0079
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0001 0.0004
Entamoeba histolytica cyclin, putative 0.016 0.0143 0.0927
Echinococcus multilocularis somatostatin receptor 0.0371 0.0357 0.0356
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0371 0.0357 0.0356
Schistosoma mansoni hypothetical protein 0.0049 0.0031 0.0032
Loa Loa (eye worm) hypothetical protein 0.2002 0.2008 0.6372
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0068 0.005 0.0116
Giardia lamblia DINP protein human, muc B family 0.0055 0.0037 0.0228
Echinococcus granulosus histone deacetylase 6 0.0894 0.0886 0.091
Brugia malayi hypothetical protein 0.0045 0.0027 0.0064
Schistosoma mansoni survival motor neuron protein 0.024 0.0224 0.023
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0128 0.0111 0.0114
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0001 0.0003
Brugia malayi Carboxylesterase family protein 0.0062 0.0044 0.0102
Plasmodium vivax histone deacetylase 1, putative 0.1545 0.1546 1
Schistosoma mansoni neuropeptide receptor 0.0371 0.0357 0.0366
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0075 0.0057 0.0365
Trypanosoma brucei mitochondrial DNA polymerase beta 0.019 0.0173 0.1117
Brugia malayi jmjC domain containing protein 0.0075 0.0057 0.0134
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0071 0.0053 0.0052
Brugia malayi Kinase associated domain 1 family protein 0.0049 0.0031 0.0072
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0143 0.0126 0.0125
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0154 0.0137 0.014
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0024 0.0006 0.0033
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0102 0.0085 0.1306
Trichomonas vaginalis cyclin B, putative 0.016 0.0143 0.0526
Entamoeba histolytica cyclin family protein 0.0083 0.0065 0.0421
Brugia malayi Carboxylesterase family protein 0.0365 0.0351 0.082
Echinococcus multilocularis tar DNA binding protein 0.0211 0.0195 0.0194
Brugia malayi Cytochrome P450 family protein 0.002 0.0001 0.0003
Mycobacterium ulcerans tryptophan-rich sensory protein 0.0637 0.0626 0.9787
Trichomonas vaginalis cyclins, putative 0.002 0.0001 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0242 0.0226 0.0831
Entamoeba histolytica protein kinase domain containing protein 0.0172 0.0155 0.1003
Loa Loa (eye worm) MH1 domain-containing protein 0.006 0.0042 0.0132
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0115 0.0098 0.1512
Onchocerca volvulus 0.004 0.0021 0.0078
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0009 0.0111
Echinococcus granulosus G1:S specific cyclin D1 0.002 0.0001 0.0001
Brugia malayi RNA recognition motif domain containing protein 0.0211 0.0195 0.0455
Echinococcus multilocularis ecdysone induced protein 78C 0.0143 0.0126 0.0125
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.0077 0.0076
Echinococcus multilocularis jumonji domain containing 1A 0.0075 0.0057 0.0056
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0207 0.0191 0.0607
Schistosoma mansoni biogenic amine receptor 0.0371 0.0357 0.0366
Brugia malayi hypothetical protein 0.0257 0.0242 0.0564
Echinococcus granulosus sex peptide receptor 0.0371 0.0357 0.0366
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0049 0.0031 0.0458
Echinococcus multilocularis thioredoxin glutathione reductase 0.0176 0.0159 0.0158
Brugia malayi Carboxylesterase family protein 0.0365 0.0351 0.082
Echinococcus multilocularis neuropeptides capa receptor 0.0371 0.0357 0.0356
Plasmodium falciparum histone deacetylase, putative 0.088 0.0872 0.5639
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Trypanosoma cruzi mitotic cyclin, putative 0.002 0.0001 0.0004
Echinococcus granulosus cyclin dependent kinase 1 0.0193 0.0177 0.0181
Schistosoma mansoni hypothetical protein 0.0071 0.0053 0.0054
Leishmania major DNA polymerase eta, putative 0.0055 0.0037 0.0228
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0103 0.0086 0.132
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0046 0.0028 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0009 0.0054
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0371 0.0357 0.1132
Entamoeba histolytica hypothetical protein 0.002 0.0001 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.0371 0.0357 0.1132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0143 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.0205 0.0189 0.06
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0019 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0057 0.0182
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0057 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0001 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0057 0.0182
Schistosoma mansoni peptidase Clp (S14 family) 0.0128 0.0111 0.0114
Schistosoma mansoni zinc finger protein 0.0019 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0371 0.0357 0.0356
Schistosoma mansoni intermediate filament proteins 0.0077 0.0059 0.0061
Echinococcus granulosus importin subunit beta 1 0.0125 0.0108 0.0111
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.0098 0.036
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0095 0.0077 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0028 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Schistosoma mansoni zinc finger protein 0.0055 0.0037 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0083 0.0065 0.0417
Echinococcus granulosus histone deacetylase 8 0.0562 0.0551 0.0565
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0045
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.002 0.0001 0.0001
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0041 0.0023 0.0023
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0047 0.0029 0.0214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Loa Loa (eye worm) isocitrate dehydrogenase 0.0024 0.0006 0.0018
Schistosoma mansoni fyve-containing 0.0019 0.0001 0.0001
Mycobacterium ulcerans polyketide synthase 0.0049 0.0031 0.0458
Onchocerca volvulus 0.0028 0.0009 0.0034
Brugia malayi Importin beta-1 subunit 0.0125 0.0108 0.0252
Echinococcus granulosus tyrosine protein kinase ABL1 0.0153 0.0136 0.0139
Toxoplasma gondii type I fatty acid synthase, putative 0.0035 0.0016 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Schistosoma mansoni tyrosine kinase 0.0037 0.0019 0.0019
Echinococcus granulosus neuropeptide receptor 0.0371 0.0357 0.0366
Brugia malayi hypothetical protein 0.0047 0.0029 0.0067
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0069 0.0051 0.0325
Onchocerca volvulus 0.0205 0.0189 0.0694
Echinococcus multilocularis mitogen activated protein kinase 0.0046 0.0028 0.0027
Trichomonas vaginalis penicillin-binding protein, putative 0.0205 0.0189 0.0694
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0005
Onchocerca volvulus 0.0085 0.0067 0.0247
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0041 0.0023 0.0073
Echinococcus granulosus lysine specific demethylase 5A 0.0301 0.0286 0.0293
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0371 0.0357 0.0356
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.0033 0.0014 0.0093
Loa Loa (eye worm) hypothetical protein 0.0637 0.0626 0.1987
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Brugia malayi hypothetical protein 0.0026 0.0007 0.0017
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0007 0.0006
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0154 0.0137 0.0136
Brugia malayi RE15519p 0.0371 0.0357 0.0833
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0143 0.0126 0.0295
Schistosoma mansoni histone deacetylase 0.1545 0.1546 0.1587
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0021 0.0078
Brugia malayi Heterochromatin protein 1 0.0242 0.0226 0.0528
Schistosoma mansoni hypothetical protein 0.0078 0.006 0.0062
Echinococcus granulosus neuropeptides capa receptor 0.0371 0.0357 0.0366
Brugia malayi Cyclin, N-terminal domain containing protein 0.016 0.0143 0.0335
Onchocerca volvulus 0.0077 0.0059 0.0218
Echinococcus multilocularis ankyrin repeat protein 0.0106 0.0089 0.0088
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0026 0.0007 0.0007
Brugia malayi Cathepsin L-like precursor 0.0028 0.0009 0.0022
Echinococcus granulosus biogenic amine 5HT receptor 0.0846 0.0838 0.086
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0026 0.0026
Echinococcus multilocularis Chromo domain 0.004 0.0021 0.002
Onchocerca volvulus 0.0371 0.0357 0.131
Brugia malayi beta-lactamase family protein 0.0205 0.0189 0.0441
Brugia malayi latrophilin 2 splice variant baaae 0.1005 0.0999 0.2333
Loa Loa (eye worm) TK/INSR protein kinase 0.0126 0.0109 0.0345
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0098 0.0628
Brugia malayi MH2 domain containing protein 0.0133 0.0116 0.0271
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.019 0.0173 0.1117
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0073 0.0055 0.0412
Echinococcus granulosus phd finger protein 10 0.0019 0.0001 0.0001
Echinococcus granulosus orexin receptor type 2 0.0371 0.0357 0.0366
Echinococcus granulosus alpha 1A adrenergic receptor 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0001 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0061 0.0043 0.0271
Brugia malayi putative neuropeptide receptor 0.0371 0.0357 0.0833
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0032 0.0014 0.0195
Trypanosoma brucei glucosidase, putative 0.0046 0.0028 0.0174
Echinococcus granulosus MAP kinase activated protein kinase 2 0.3131 0.3151 0.3235
Schistosoma mansoni DNA polymerase eta 0.0055 0.0037 0.0038
Loa Loa (eye worm) hypothetical protein 0.0358 0.0343 0.1089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0001 0.0005
Echinococcus multilocularis regulator of G protein signaling 3 0.0026 0.0007 0.0006
Onchocerca volvulus 0.0062 0.0044 0.0161
Brugia malayi nuclear receptor NHR-67 0.0068 0.005 0.0116
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.004 0.0296
Mycobacterium leprae Probable lipase LipE 0.0205 0.0189 0.2938
Onchocerca volvulus Poor gastrulation protein homolog 0.0046 0.0028 0.0103
Brugia malayi cell division control protein 2 homolog 0.0193 0.0177 0.0413
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0019 0.0001 0.0001
Echinococcus multilocularis cyclin G2 0.002 0.0001 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0061 0.0043 0.0271
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0044 0.0026 0.0382
Schistosoma mansoni alpha-1 adrenergic receptor 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0039 0.002 0.0065
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.0077 0.0079
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0172 0.0155 0.0159
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.004 0.0252
Echinococcus multilocularis acetylcholinesterase 0.0365 0.0351 0.035
Schistosoma mansoni opsin-like receptor 0.0371 0.0357 0.0366
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0101 0.0084 0.0308
Echinococcus multilocularis G-protein coupled receptor, putative 0.0371 0.0357 0.0356
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0024 0.0006 0.0005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.0009 0.0029
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0371 0.0357 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus neuropeptide s receptor 0.06 0.0588 0.0604
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0028 0.0102
Plasmodium falciparum zinc finger protein, putative 0.0033 0.0014 0.0088
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0001 0.0004
Echinococcus granulosus epidermal growth factor receptor 0.0099 0.0082 0.0084
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0001 0.0002
Echinococcus granulosus histone deacetylase 1 0.1545 0.1546 0.1587
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0098 0.0628
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0043 0.0271
Mycobacterium tuberculosis Probable thioesterase TesA 0.0041 0.0022 0.0162
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.004 0.0021 0.0132
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0059 0.0041 0.0262
Schistosoma mansoni hypothetical protein 0.0049 0.0031 0.0032
Plasmodium vivax multidomain scavenger receptor, putative 0.0047 0.0029 0.018
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0199 0.0182 0.0187
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.002 0.0001 0.0004
Onchocerca volvulus 0.0046 0.0027 0.0101
Schistosoma mansoni phd/f-box containing protein 0.0075 0.0057 0.0059
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.002 0.0001 0.0004
Trichomonas vaginalis hypothetical protein 0.004 0.0021 0.0078
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus thyroid hormone receptor alpha 0.0068 0.005 0.0051
Loa Loa (eye worm) carboxylesterase 0.0365 0.0351 0.1114
Echinococcus multilocularis Regulator of G protein signaling 20 0.0026 0.0007 0.0006
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0039 0.0021 0.0021
Leishmania major cytochrome p450-like protein 0.002 0.0001 0.0000072158
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.004 0.0093
Treponema pallidum DNA polymerase III subunit alpha 0.0102 0.0084 0.0558
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0006 0.0031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1471 0.147 0.4666
Brugia malayi Pre-SET motif family protein 0.0345 0.0331 0.0773
Brugia malayi Histone deacetylase family protein 0.088 0.0872 0.2036
Schistosoma mansoni growth hormone secretagogue receptor 0.0371 0.0357 0.0366
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0089 0.0072 0.0263
Brugia malayi Bromodomain associated family protein 0.0019 0.0001 0.0002
Echinococcus multilocularis serotonin receptor 0.0846 0.0838 0.0837
Loa Loa (eye worm) hypothetical protein 0.069 0.0679 0.2156
Echinococcus granulosus dnaJ subfamily B 0.2847 0.2864 0.294
Brugia malayi Thioredoxin reductase 0.0175 0.0159 0.0371
Onchocerca volvulus Serine\/threonine kinase homolog 0.0132 0.0115 0.0422
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0046 0.0028 0.0088
Plasmodium vivax heterochromatin protein 1, putative 0.004 0.0021 0.0132
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1335 0.1333 0.423
Brugia malayi histone deacetylase 3 (HD3) 0.1545 0.1546 0.3609
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0069 0.0051 0.0119
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0006 0.0005
Brugia malayi isocitrate dehydrogenase 0.0024 0.0006 0.0013
Schistosoma mansoni cyclin k 0.002 0.0001 0.0001
Echinococcus multilocularis para nitrobenzyl esterase 0.0062 0.0044 0.0043
Giardia lamblia Kinase, PLK 0.0132 0.0115 0.0736
Schistosoma mansoni jumonji domain containing protein 0.0534 0.0522 0.0536
Echinococcus multilocularis neuropeptide receptor 0.0371 0.0357 0.0356
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0029 0.0011 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0143 0.0126 0.013
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0028 0.0102
Plasmodium falciparum heterochromatin protein 1 0.004 0.0021 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0385 0.0371 0.0381
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Echinococcus multilocularis muscleblind protein 0.0081 0.0063 0.0063
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0445 0.0431 0.3291
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0256 0.024 0.0247
Echinococcus granulosus GTP binding nuclear protein Ran 0.0069 0.0051 0.0052
Echinococcus multilocularis histone deacetylase 7 0.088 0.0872 0.0871
Leishmania major cathepsin L-like protease 0.0106 0.0088 0.0562
Schistosoma mansoni cyclin d 0.002 0.0001 0.0001
Brugia malayi ERG2 and Sigma1 receptor like protein 0.102 0.1014 0.2367
Echinococcus granulosus Nuclear hormone receptor HR96 0.0068 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus protein kinase shaggy 0.0172 0.0155 0.0159
Brugia malayi Tyrosine-protein kinase abl-1 0.0065 0.0047 0.0109
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0018
Leishmania major cytochrome p450-like protein 0.002 0.0001 0.0000072158
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0037 0.0271
Onchocerca volvulus 0.0637 0.0626 0.23
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.004 0.0021 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Brugia malayi ORL1-like opioid receptor 0.0371 0.0357 0.0833
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0006 0.0013
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0061 0.0043 0.0271
Echinococcus multilocularis isocitrate dehydrogenase 0.0024 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0023
Mycobacterium ulcerans esterase/lipase LipP 0.0205 0.0189 0.2938
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0049 0.0031 0.0032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0407 0.0394 0.0393
Trypanosoma cruzi cyclin 6, putative 0.016 0.0143 0.0922
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.004 0.0021 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.008 0.0063 0.0062
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0067 0.0049 0.005
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0009 0.0049
Schistosoma mansoni neuropeptide receptor 0.0371 0.0357 0.0366
Brugia malayi Bromodomain containing protein 0.0144 0.0127 0.0298
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0026 0.0007 0.0007
Echinococcus multilocularis protein kinase shaggy 0.0172 0.0155 0.0154
Loa Loa (eye worm) hypothetical protein 0.0077 0.0059 0.0189
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Loa Loa (eye worm) cyclin domain-containing protein 0.002 0.0001 0.0005
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.054 0.1985
Echinococcus multilocularis muscleblind protein 1 0.0081 0.0063 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.1956 0.1962 0.6224
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0143 0.0126 0.0401
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0813 0.0805 0.2553
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Echinococcus multilocularis translocator protein 0.0637 0.0626 0.0625
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0019 0.012
Schistosoma mansoni tar DNA-binding protein 0.0211 0.0195 0.02
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0371 0.0357 0.0833
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.054 0.1985
Brugia malayi G protein-coupled receptor F59B2.13 0.0371 0.0357 0.0833
Brugia malayi nuclear receptor NHR-88 0.0068 0.005 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0095 0.0348
Brugia malayi regulator of G-protein signaling rgs-7 0.0026 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0076 0.0058 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0177 0.0649
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0061 0.0043 0.3202
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0039 0.0021 0.0306
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0128 0.0111 1
Echinococcus multilocularis survival motor neuron protein 1 0.1176 0.1172 0.1171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Loa Loa (eye worm) nuclear receptor NHR-67 0.0068 0.005 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.0189 0.0694
Echinococcus multilocularis cpg binding protein 0.0238 0.0223 0.0222
Echinococcus multilocularis g-protein coupled receptor 0.0371 0.0357 0.0356
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0045
Giardia lamblia NADPH oxidoreductase, putative 0.0065 0.0047 0.0293
Echinococcus multilocularis lipoxygenase domain containing protein 0.0047 0.0029 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0078 0.0288
Leishmania major DNA polymerase kappa, putative 0.0055 0.0037 0.0228
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0052 0.0034 0.0249
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0115 0.0097 0.0622
Brugia malayi conserved hypotetical protein 0.0068 0.005 0.0116
Loa Loa (eye worm) transcription factor SMAD2 0.1956 0.1962 0.6224
Loa Loa (eye worm) hypothetical protein 0.0081 0.0063 0.0201
Trypanosoma brucei glycosomal malate dehydrogenase 0.0024 0.0005 0.003
Brugia malayi Inositol-1 0.0115 0.0098 0.0229
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0465 0.0452 0.0452
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0101 0.0084 0.0308
Brugia malayi PHD-finger family protein 0.0019 0.0001 0.0002
Echinococcus multilocularis neuroligin 0.0062 0.0044 0.0043
Toxoplasma gondii PHD-finger domain-containing protein 0.0182 0.0165 0.1063
Echinococcus granulosus fmrfamide receptor 0.0371 0.0357 0.0366
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0052 0.0034 0.0506
Onchocerca volvulus Alhambra homolog 0.0182 0.0165 0.0606
Plasmodium falciparum glutathione reductase 0.0061 0.0043 0.0271
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0109 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Schistosoma mansoni tar DNA-binding protein 0.0211 0.0195 0.02
Trypanosoma brucei PAB1-binding protein , putative 0.0158 0.0141 0.0907
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0143 0.0126 0.0295
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0039 0.0021 0.0048
Schistosoma mansoni terminal deoxycytidyl transferase 0.0055 0.0037 0.0038
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0006 0.0013
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0049 0.0031 0.0225
Schistosoma mansoni chromobox protein 0.004 0.0021 0.0022
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0095 0.0077 0.0076
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0006
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0071 0.0053 0.0054
Brugia malayi Valyl-tRNA synthetase 0.004 0.0021 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0068 0.005 0.0182
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0043 0.0409
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0046 0.0028 0.0089
Onchocerca volvulus 0.0371 0.0357 0.131
Plasmodium falciparum histone deacetylase 1 0.1545 0.1546 1
Onchocerca volvulus 0.0028 0.0009 0.0034
Echinococcus multilocularis nmda type glutamate receptor 0.0041 0.0022 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0028 0.0102
Toxoplasma gondii cathepsin CPL 0.0028 0.0009 0.0054
Echinococcus multilocularis Chromobox protein 3 0.004 0.0021 0.002
Brugia malayi hypothetical protein 0.004 0.0021 0.005
Onchocerca volvulus 0.0137 0.0119 0.0439
Brugia malayi Carboxylesterase family protein 0.0062 0.0044 0.0102
Trichomonas vaginalis DNA polymerase eta, putative 0.0055 0.0037 0.0135
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0068 0.005 0.0182
Toxoplasma gondii HEAT repeat-containing protein 0.0024 0.0005 0.0028
Echinococcus granulosus lipoxygenase domain containing protein 0.0047 0.0029 0.0029
Trichomonas vaginalis cyclin B, putative 0.016 0.0143 0.0526
Echinococcus multilocularis GA binding protein alpha chain 0.0046 0.0028 0.0027
Schistosoma mansoni hypothetical protein 0.0078 0.006 0.0062
Schistosoma mansoni tyrosine kinase 0.0037 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0026 0.0007 0.0047
Echinococcus granulosus JmjC domain containing protein 4 0.0075 0.0057 0.0059
Echinococcus multilocularis g protein coupled receptor 0.0371 0.0357 0.0356
Leishmania major cytochrome p450-like protein 0.0027 0.0009 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0044 0.0046
Echinococcus granulosus dual specificity 0.0115 0.0097 0.01
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0098 0.0625
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Loa Loa (eye worm) hypothetical protein 0.0637 0.0626 0.1987
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0143 0.0126 0.013
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0172 0.0155 0.0998
Loa Loa (eye worm) solute carrier family 6 member 4 0.0558 0.0547 0.1735
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Brugia malayi cytoplasmic intermediate filament protein 0.0041 0.0023 0.0054
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0046 0.0028 0.0175
Brugia malayi hypothetical protein 0.0033 0.0014 0.0033
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.002 0.0001 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0007 0.0007
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0047 0.0029 0.0214
Echinococcus multilocularis tyrosine kinase 0.0037 0.0019 0.0018
Loa Loa (eye worm) cyclin domain-containing protein 0.0256 0.024 0.0763
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.054 0.1985
Plasmodium vivax protein kinase Crk2 0.0193 0.0177 0.1139
Leishmania major importin beta-1 subunit, putative 0.0101 0.0084 0.0534
Schistosoma mansoni dpf3 0.0019 0.0001 0.0001
Schistosoma mansoni z-protein (S1r protein) 0.0026 0.0007 0.0007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.018
Loa Loa (eye worm) serotonin transporter b 0.0558 0.0547 0.1735
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0068 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0125 0.0108 0.0342
Brugia malayi Dopamine receptor protein 1 0.069 0.0679 0.1586
Onchocerca volvulus 0.2708 0.2723 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0037 0.0019 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0177 0.0649
Echinococcus granulosus intermediate filament protein 0.0077 0.0059 0.0061
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0061 0.0043 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi hypothetical protein 0.0076 0.0058 0.0135
Brugia malayi Cathepsin L-like precursor 0.0028 0.0009 0.0022
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0062 0.0044 0.0045
Trypanosoma cruzi mitotic cyclin, putative 0.002 0.0001 0.0004
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1545 0.1546 0.5677
Brugia malayi CXXC zinc finger family protein 0.0219 0.0203 0.0474
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0465 0.0452 0.0464
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0189 0.1217
Echinococcus multilocularis sex peptide receptor 0.0371 0.0357 0.0356
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.0189 0.0694
Brugia malayi Pre-SET motif family protein 0.2379 0.239 0.5581
Plasmodium vivax SET domain containing protein 0.0031 0.0013 0.0079
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.0026 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0001 0.0002
Onchocerca volvulus 0.0028 0.0009 0.0034
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.002 0.0001 0.0001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.002 0.0001 0.0003
Onchocerca volvulus 0.0033 0.0014 0.0053
Entamoeba histolytica cyclin, domain containing protein 0.002 0.0001 0.0009
Brugia malayi Cathepsin L-like precursor 0.0028 0.0009 0.0022
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.0098 0.036
Schistosoma mansoni tyrosine kinase 0.0099 0.0082 0.0084
Brugia malayi hypothetical protein 0.0055 0.0037 0.0087
Schistosoma mansoni cyclin G 0.002 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0371 0.0357 0.0366
Schistosoma mansoni hypothetical protein 0.0371 0.0357 0.0366
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0335 0.0321 0.0329
Trypanosoma brucei histone deacetylase 2 0.0562 0.0551 0.3559
Plasmodium vivax cyclin homologue, putative 0.002 0.0001 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Toxoplasma gondii hypothetical protein 0.0095 0.0077 0.0494
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0199 0.0182 0.0181
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0006 0.0005
Echinococcus granulosus transient receptor potential cation channel 0.0117 0.01 0.0102
Schistosoma mansoni tyrosine kinase 0.0151 0.0134 0.0137
Trypanosoma cruzi DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Schistosoma mansoni adenoreceptor 0.0371 0.0357 0.0366
Loa Loa (eye worm) hypothetical protein 0.0101 0.0084 0.0266
Onchocerca volvulus 0.0047 0.0029 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0143 0.0126 0.0295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0371 0.0357 0.0366
Echinococcus multilocularis BC026374 protein (S09 family) 0.0062 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.004 0.0021 0.0132
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.006
Echinococcus granulosus neuropeptide receptor 0.0371 0.0357 0.0366
Brugia malayi Cyclin, N-terminal domain containing protein 0.002 0.0001 0.0003
Echinococcus granulosus lysine specific demethylase 6a 0.0075 0.0057 0.0059
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0006 0.0006
Echinococcus granulosus GA binding protein alpha chain 0.0046 0.0028 0.0029
Trypanosoma cruzi PAB1-binding protein , putative 0.0158 0.0141 0.0907
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0061 0.0043 0.0044
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0049 0.0031 0.0225
Onchocerca volvulus Huntingtin homolog 0.0167 0.0151 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0021 0.0022
Giardia lamblia G2/mitotic-specific cyclin B 0.016 0.0143 0.0919
Onchocerca volvulus 0.0371 0.0357 0.131
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0465 0.0452 0.1056
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.008 0.0063 0.0064
Schistosoma mansoni tyrosine kinase 0.0126 0.0109 0.0112
Schistosoma mansoni glutamate receptor NMDA 0.0044 0.0026 0.0027
Schistosoma mansoni opsin-like receptor 0.0371 0.0357 0.0366
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0259 0.0243 0.0568
Loa Loa (eye worm) TK/ABL protein kinase 0.0153 0.0136 0.0431
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0371 0.0357 0.0356
Echinococcus multilocularis peptidase Clp (S14 family) 0.0084 0.0066 0.0065
Brugia malayi Cytochrome P450 family protein 0.0027 0.0009 0.002
Trichomonas vaginalis spcc417.12 protein, putative 0.0062 0.0044 0.0161
Brugia malayi PHD-finger family protein 0.0182 0.0165 0.0385
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0143 0.0126 0.0295
Schistosoma mansoni Smad4 0.006 0.0042 0.0043
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0076 0.0058 0.0059
Loa Loa (eye worm) hypothetical protein 0.1005 0.0999 0.3171
Entamoeba histolytica hypothetical protein 0.004 0.0021 0.0138
Brugia malayi Cyclin, N-terminal domain containing protein 0.016 0.0143 0.0335
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Brugia malayi G protein-coupled receptor 0.0371 0.0357 0.0833
Trichomonas vaginalis alpha-glucosidase, putative 0.0046 0.0028 0.0102
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.065 0.064 1
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus 7tm_1 domain containing protein 0.0371 0.0357 0.0366
Onchocerca volvulus 0.0371 0.0357 0.131
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0009 0.0027
Echinococcus granulosus muscleblind protein 0.0081 0.0063 0.0065
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Loa Loa (eye worm) histone methyltransferase 0.008 0.0063 0.0198
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0143 0.0126 0.0295
Loa Loa (eye worm) hypothetical protein 0.102 0.1014 0.3217
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0055 0.0037 0.0038
Mycobacterium ulcerans thioesterase 0.0041 0.0022 0.0329
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.002 0.0001 0.0001
Schistosoma mansoni importin beta-1 0.0125 0.0108 0.0111
Brugia malayi Latrophilin receptor protein 2 0.0465 0.0452 0.1056
Leishmania major glycosomal malate dehydrogenase 0.0024 0.0005 0.0026
Onchocerca volvulus 0.0028 0.0009 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0007 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0028
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0161 0.0144 0.0458
Schistosoma mansoni cyclin l 0.002 0.0001 0.0001
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0055 0.0037 0.0135
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.004 0.0021 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.002 0.0001 0.0009
Mycobacterium ulcerans polyketide synthase Pks9 0.0032 0.0014 0.0195
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus beta LACTamase domain containing family member 0.0205 0.0189 0.0194
Plasmodium vivax thioredoxin reductase, putative 0.0175 0.0159 0.1022
Trichomonas vaginalis chromobox protein, putative 0.004 0.0021 0.0078
Loa Loa (eye worm) hypothetical protein 0.0099 0.0082 0.0259
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus multilocularis lysosomal alpha glucosidase 0.0207 0.0191 0.019
Loa Loa (eye worm) fatty acid synthase 0.0048 0.003 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Echinococcus granulosus zinc finger protein 0.0089 0.0071 0.0073
Loa Loa (eye worm) RGS-3 protein 0.0026 0.0007 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.054 0.1985
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Echinococcus multilocularis cyclin G2 0.002 0.0001 0.0001
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.0008 0.0048
Trypanosoma brucei histone deacetylase, putative 0.088 0.0872 0.5639
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0075 0.0057 0.0363
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0044 0.0026 0.0161
Trichomonas vaginalis cyclin B, putative 0.002 0.0001 0.0005
Giardia lamblia Hypothetical protein 0.0083 0.0065 0.0412
Echinococcus multilocularis tumor protein p63 0.0933 0.0926 0.0925
Brugia malayi MH1 domain containing protein 0.0074 0.0056 0.013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0477 0.0464 0.0477
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0005
Toxoplasma gondii histone deacetylase HDAC3 0.1545 0.1546 1
Entamoeba histolytica cyclin, putative 0.0083 0.0065 0.0421
Plasmodium falciparum phd finger protein, putative 0.0182 0.0165 0.1063
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0021 0.0078
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0046 0.0028 0.0175
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.0077 0.0494
Schistosoma mansoni requim req/dpf2 0.0019 0.0001 0.0001
Echinococcus granulosus dna polymerase kappa 0.0055 0.0037 0.0038
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0001 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0098 0.0628
Echinococcus granulosus cyclins 0.002 0.0001 0.0001
Brugia malayi Ets-domain containing protein 0.0046 0.0028 0.0066
Schistosoma mansoni sodium-dependent amino acid transporter 0.0095 0.0077 0.0079
Schistosoma mansoni nuclear hormone receptor 0.0143 0.0126 0.013
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0001 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0205 0.0189 0.06
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0001 0.0004
Echinococcus granulosus nmda type glutamate receptor 0.0041 0.0022 0.0023
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.004 0.0021 0.0132
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0069 0.0051 0.0325
Loa Loa (eye worm) hypothetical protein 0.0039 0.002 0.0065
Schistosoma mansoni aldehyde dehydrogenase 0.0199 0.0182 0.0187
Echinococcus granulosus peregrin 0.0196 0.0179 0.0184
Echinococcus granulosus remodeling and spacing factor 1 0.0019 0.0001 0.0001
Schistosoma mansoni myst-related protein 0.0033 0.0014 0.0015
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0371 0.0357 0.1132
Trypanosoma cruzi C-8 sterol isomerase, putative 0.102 0.1014 0.6557
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0048
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0055 0.0037 0.0271
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0046 0.0027 0.0087
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0172 0.0155 0.0998
Schistosoma mansoni ap endonuclease 0.0058 0.004 0.0041
Entamoeba histolytica protein kinase, putative 0.0115 0.0097 0.0631
Schistosoma mansoni neuropeptide f receptor 76f 0.0371 0.0357 0.0366
Giardia lamblia Kinase, CMGC MAPK 0.0046 0.0028 0.0171
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0256 0.024 0.0239
Schistosoma mansoni nuclear receptor 0.0068 0.005 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0089 0.0072 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0031 0.0116
Echinococcus multilocularis cyclin dependent kinase 1 0.0193 0.0177 0.0176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0076 0.0058 0.0184
Brugia malayi Carboxylesterase family protein 0.0062 0.0044 0.0102
Loa Loa (eye worm) hypothetical protein 0.0558 0.0547 0.1735
Trypanosoma cruzi DNA polymerase eta, putative 0.0055 0.0037 0.0232
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0009 0.0027
Entamoeba histolytica cyclin C, putative 0.002 0.0001 0.0009
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0193 0.0177 0.1136
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0028 0.0102
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0371 0.0357 0.0366
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0322 0.0308 0.0307
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0041 0.0262
Schistosoma mansoni Smad4 0.006 0.0042 0.0043
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0055 0.0349
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.002 0.0001 0.0004
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0059 0.0041 0.0262
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0345 0.0331 0.034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0067 0.0049 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus granulosus Chromo domain 0.004 0.0021 0.0022
Echinococcus granulosus cyclin 0.002 0.0001 0.0001
Echinococcus granulosus Cyclin L1 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0109 0.0091 0.0289
Echinococcus granulosus neuropeptides capa receptor 0.0371 0.0357 0.0366
Onchocerca volvulus 0.0068 0.005 0.0182
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0012 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.004 0.0252
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0046 0.0028 0.0175
Echinococcus granulosus importin 5 0.0024 0.0005 0.0005
Schistosoma mansoni phosphatidylserine receptor 0.0075 0.0057 0.0059
Plasmodium vivax vivapain-2 0.0028 0.0009 0.0054
Plasmodium vivax glutathione reductase, putative 0.0175 0.0159 0.1022
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0227 0.0211 0.0216
Trichomonas vaginalis cyclins, putative 0.0083 0.0065 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.0009 0.0034
Schistosoma mansoni cytochrome P450 0.002 0.0001 0.0001
Echinococcus multilocularis zinc finger protein 0.0089 0.0071 0.007
Echinococcus granulosus serotonin transporter 0.0558 0.0547 0.0561
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0128 0.0111 0.1712
Echinococcus granulosus regulator of G protein signaling 3 0.0026 0.0007 0.0007
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.002 0.0001 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0158 0.0141 0.0907
Loa Loa (eye worm) steroid hormone receptor 0.0143 0.0126 0.0401
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Loa Loa (eye worm) PHD-finger family protein 0.0182 0.0165 0.0524
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0188 0.0172 0.1113
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.0077 0.0079
Loa Loa (eye worm) hypothetical protein 0.0075 0.0057 0.0182
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0023
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0026 0.0007 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0076 0.0058 0.0135
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0371 0.0357 0.0833
Brugia malayi Serotonin receptor 0.0371 0.0357 0.0833
Echinococcus multilocularis chromobox protein 2 0.004 0.0021 0.002
Brugia malayi jmjC domain containing protein 0.0075 0.0057 0.0134
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0205 0.0189 0.1436
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0061 0.0043 0.0271
Onchocerca volvulus 0.0095 0.0077 0.0284
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0656 0.0646 0.0663
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0045
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0001 0.0002
Loa Loa (eye worm) cytochrome P450 0.002 0.0001 0.0004
Trypanosoma cruzi ISWI complex protein 0.0023 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0007 0.0007
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0006 0.0005
Loa Loa (eye worm) cysteine protease 0.0028 0.0009 0.0029
Brugia malayi hypothetical protein 0.002 0.0001 0.0003
Schistosoma mansoni protein phosphatase 2C 0.0075 0.0057 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0037 0.0232
Schistosoma mansoni neuroligin 3 (S09 family) 0.0062 0.0044 0.0045
Onchocerca volvulus 0.0019 0.0001 0.0003
Onchocerca volvulus 0.0047 0.0029 0.0105
Loa Loa (eye worm) carboxylesterase 0.0062 0.0044 0.0139
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0046 0.0028 0.0088
Echinococcus granulosus nmda type glutamate receptor 0.0033 0.0014 0.0015
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0024 0.0005 0.003
Loa Loa (eye worm) G-protein coupled receptor 0.0371 0.0357 0.1132
Echinococcus multilocularis lamin dm0 0.0077 0.0059 0.0058
Echinococcus granulosus biogenic amine 5HT receptor 0.2643 0.2657 0.2728
Plasmodium falciparum cysteine proteinase falcipain 3 0.0028 0.0009 0.0054
Brugia malayi PXA domain containing protein 0.0026 0.0007 0.0017
Schistosoma mansoni rab6-interacting 0.0047 0.0029 0.0029
Trichomonas vaginalis chromobox protein, putative 0.004 0.0021 0.0078
Echinococcus granulosus nuclear factor of activated T cells 5 0.009 0.0072 0.0074
Schistosoma mansoni lamin 0.0077 0.0059 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.5098 0.5143 0.5143
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0069 0.0051 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0115 0.0422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Schistosoma mansoni cyclin B 0.016 0.0143 0.0147
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0106 0.0088 0.0565
Schistosoma mansoni tyrosine kinase 0.0095 0.0077 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Echinococcus granulosus cyclin y 0.002 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0106 0.0088 0.0562
Schistosoma mansoni biogenic amine (5HT) receptor 0.2643 0.2657 0.2728
Echinococcus multilocularis cyclin k 0.002 0.0001 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0234 0.0218 0.0223
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0019 0.0001 0.0001
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0037 0.0019 0.0116
Brugia malayi MH1 domain containing protein 0.0133 0.0116 0.0271
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.002 0.0001 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0028 0.0102
Echinococcus multilocularis g protein coupled receptor 0.0371 0.0357 0.0356
Schistosoma mansoni tyrosine kinase 0.0147 0.013 0.0133
Loa Loa (eye worm) hypothetical protein 0.0331 0.0317 0.1005
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0021 0.002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0371 0.0357 0.0833
Brugia malayi kap beta 3 protein 0.0024 0.0005 0.0012
Onchocerca volvulus 0.0062 0.0044 0.0161
Echinococcus multilocularis regulator of G protein signaling 0.0026 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0371 0.0357 0.0366
Brugia malayi glutaminase DH11.1 0.0175 0.0159 0.0371
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0371 0.0357 0.0366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0371 0.0357 0.0356
Schistosoma mansoni smad1 5 8 and 0.0133 0.0116 0.0119
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0076 0.0058 0.0057
Onchocerca volvulus 0.0062 0.0044 0.0161
Echinococcus multilocularis tyrosine protein kinase Abl 0.0065 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0362 0.0348 0.1279
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0041 0.0023 0.0053
Mycobacterium ulcerans hypothetical protein 0.0205 0.0189 0.2938
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0102 0.0084 0.7358
Onchocerca volvulus Cathepsin F homolog 0.0028 0.0009 0.0034
Echinococcus granulosus TGF beta signal transducer SmadC 0.0133 0.0116 0.0119
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.004 0.0602
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0061 0.0043 0.0268
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0049 0.0031 0.0197
Brugia malayi Bromodomain containing protein 0.029 0.0275 0.0642
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0044 0.0046
Echinococcus multilocularis peregrin 0.0196 0.0179 0.0178
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0155 0.0569
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0001 0.0003
Mycobacterium ulcerans DNA polymerase IV 0.0055 0.0037 0.0552
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0172 0.0155 0.0159
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.0009 0.0008
Echinococcus multilocularis nuclear receptor nhr 48 0.0068 0.005 0.0049
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0046 0.0028 0.0175
Plasmodium falciparum SNF2 helicase, putative 0.0019 0.0001 0.000000000065333
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0045 0.0026 0.0062
Onchocerca volvulus Fatty acid synthase homolog 0.0088 0.007 0.0258
Leishmania major alpha glucosidase II subunit, putative 0.0046 0.0028 0.0171
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0037 0.0232
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.002 0.0001 0.0001
Schistosoma mansoni patched 1 0.0081 0.0063 0.0065
Loa Loa (eye worm) nuclear factor I 0.0074 0.0056 0.0177
Entamoeba histolytica hypothetical protein 0.004 0.0021 0.0138
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0371 0.0357 0.0356
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0007 0.0007
Mycobacterium ulcerans DNA polymerase IV 0.0055 0.0037 0.0552
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0205 0.0189 0.2938
Onchocerca volvulus 0.004 0.0021 0.0078
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0371 0.0357 0.0356
Leishmania major protein kinase, putative 0.003 0.0012 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0007 0.0027
Echinococcus granulosus sterol regulatory element binding protein 0.0081 0.0063 0.0065
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0558 0.0547 0.1735
Echinococcus granulosus Chromobox protein 3 0.004 0.0021 0.0022
Onchocerca volvulus 0.0037 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0055
Brugia malayi sulfakinin receptor protein 0.0371 0.0357 0.0833
Brugia malayi hypothetical protein 0.0371 0.0357 0.0833
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0061 0.0043 0.0318
Trichomonas vaginalis cyclins, putative 0.0097 0.008 0.0293
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0205 0.0189 0.0441
Brugia malayi beta-lactamase 0.0205 0.0189 0.0441
Onchocerca volvulus 0.0062 0.0044 0.0161
Toxoplasma gondii thioredoxin reductase 0.0175 0.0159 0.1022
Echinococcus multilocularis lipoxygenase domain containing protein 0.0047 0.0029 0.0028
Loa Loa (eye worm) kap beta 3 protein 0.0024 0.0005 0.0016
Schistosoma mansoni phd finger protein 0.0019 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0021 0.0022
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0006 0.0037
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0358 0.0343 0.0342
Mycobacterium tuberculosis Probable hydrolase 0.0205 0.0189 0.1436
Echinococcus multilocularis axis inhibition protein axin 0.0026 0.0007 0.0006
Echinococcus granulosus calcium activated potassium channel 0.0073 0.0055 0.0057
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0371 0.0357 0.0366
Brugia malayi Protein kinase domain containing protein 0.0161 0.0144 0.0337
Echinococcus granulosus geminin 0.4655 0.4695 0.4819
Echinococcus multilocularis mitogen activated protein kinase 3 0.0046 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0046 0.0028 0.0089
Echinococcus multilocularis 0.002 0.0001 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.0077 0.0079
Schistosoma mansoni g1/s-specific cyclin C 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0068 0.005 0.0158
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0093 0.0075 0.0175
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0169 0.0153 0.0157
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.004 0.0021 0.0132
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0089 0.0072 0.0263
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0193 0.0177 0.0561
Echinococcus multilocularis histone deacetylase 0.088 0.0872 0.0871
Brugia malayi hypothetical protein 0.0076 0.0058 0.0135
Plasmodium vivax glycogen synthase kinase 3, putative 0.0172 0.0155 0.0998
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Echinococcus granulosus cyclins 0.0083 0.0065 0.0067
Brugia malayi Receptor family ligand binding region containing protein 0.0037 0.0019 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.3131 0.3151 0.3235
Schistosoma mansoni smad 0.006 0.0042 0.0043
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.009 0.0072 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0047 0.0171
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0039 0.002 0.0048
Echinococcus granulosus GPCR family 3 C terminal 0.0046 0.0028 0.0029
Trypanosoma brucei mitotic cyclin 0.002 0.0001 0.0004
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0001 0.0002
Echinococcus granulosus expressed protein 0.0458 0.0445 0.0456
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0006 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0021 0.0078
Loa Loa (eye worm) hypothetical protein 0.0081 0.0063 0.0201
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0081 0.0063 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0065 0.0239
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0038 0.002 0.0145
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0041 0.0022 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0371 0.0357 0.0366
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0062 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0188 0.0172 0.0546
Brugia malayi MH2 domain containing protein 0.0133 0.0116 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.003 0.0111
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0371 0.0357 0.1132
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0001 0.0003
Echinococcus granulosus BC026374 protein S09 family 0.0062 0.0044 0.0045
Trichomonas vaginalis bromodomain-containing protein, putative 0.0075 0.0057 0.0209
Mycobacterium tuberculosis Conserved protein 0.0205 0.0189 0.1436
Echinococcus granulosus tm gpcr rhodopsin 0.0371 0.0357 0.0366
Echinococcus multilocularis cyclin dependent kinase 1 0.0193 0.0177 0.0176
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0115 0.0097 0.0625
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0059 0.0041 0.0042
Brugia malayi Furin-like cysteine rich region family protein 0.0147 0.013 0.0303
Loa Loa (eye worm) hypothetical protein 0.0637 0.0626 0.1987
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0049 0.0031 0.0458
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0068
Echinococcus multilocularis cyclins 0.0083 0.0065 0.0064
Echinococcus granulosus bloom syndrome protein 0.0024 0.0006 0.0006
Schistosoma mansoni methyl-cpg binding protein mbd 0.0062 0.0044 0.0045
Echinococcus multilocularis neuropeptide s receptor 0.06 0.0588 0.0587
Echinococcus multilocularis dna polymerase kappa 0.0055 0.0037 0.0036
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.019 0.0173 0.1117
Echinococcus multilocularis Niemann Pick C1 protein 0.0188 0.0172 0.0171
Mycobacterium ulcerans aldehyde dehydrogenase 0.0199 0.0182 0.2834
Loa Loa (eye worm) hypothetical protein 0.0101 0.0084 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0007 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0009 0.0034
Echinococcus multilocularis L aminoadipate semialdehyde 0.0041 0.0023 0.0022
Echinococcus multilocularis cyclin b3 0.0083 0.0065 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0143 0.0126 0.0401
Echinococcus granulosus PHD finger protein 14 0.0019 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0102 0.0084 0.6273
Schistosoma mansoni nuclear hormone receptor 0.0068 0.005 0.0051
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0049 0.0031 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0007 0.0027
Plasmodium falciparum thioredoxin reductase 0.0061 0.0043 0.0271
Giardia lamblia Kinase, CMGC CDK 0.0193 0.0177 0.1136
Echinococcus multilocularis histone deacetylase 6 0.0894 0.0886 0.0885
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0009 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Echinococcus granulosus cyclin B 0.016 0.0143 0.0147
Echinococcus granulosus rhodopsin orphan GPCR 0.0371 0.0357 0.0366
Schistosoma mansoni Smad4 0.0133 0.0116 0.0119
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0328 0.0313 0.0322
Echinococcus granulosus thioredoxin glutathione reductase 0.0176 0.0159 0.0164
Echinococcus multilocularis transient receptor potential cation channel 0.0117 0.01 0.0099
Brugia malayi Histone deacetylase family protein 0.088 0.0872 0.2036
Loa Loa (eye worm) hypothetical protein 0.0095 0.0077 0.0245
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.04 0.0386 0.2945
Echinococcus multilocularis nmda type glutamate receptor 0.0033 0.0014 0.0013
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0009 0.001
Loa Loa (eye worm) PXA domain-containing protein 0.0026 0.0007 0.0023
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0325 0.031 0.0318
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Leishmania major GTP-binding protein, putative 0.0069 0.0051 0.0322
Toxoplasma gondii type I fatty acid synthase, putative 0.0052 0.0034 0.0213
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1331 0.1329 0.8601
Toxoplasma gondii isocitrate dehydrogenase 0.0024 0.0006 0.003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0235 0.0219 0.0224
Loa Loa (eye worm) hypothetical protein 0.0371 0.0357 0.1132
Echinococcus granulosus tyrosine kinase 0.0037 0.0019 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1331 0.1329 0.4883
Trichomonas vaginalis cyclins, putative 0.016 0.0143 0.0526
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0061 0.0043 0.0271
Schistosoma mansoni histone deacetylase hda2 0.0562 0.0551 0.0565
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0021 0.0049

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 43 nM BindingDB_Patents: Kinase Assay. MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a substrate. The extent of FITC-labeled histone H3 peptide phosphorylation was measured by immobilized metal ion affinity-based fluorescence polarization (IMAP) technology (Sportsman J R, et al., Assay Drug Dev. Technol. 2: 205-14, 2004) using IMAP FP Progressive Binding System (Molecular Devices Corporation). Test compounds were dissolved in DMSO at 12.5 mM and then serially diluted as the DMSO concentration in the assays to be 1%. The serially diluted compounds, 0.8 ng/micro-L PBK (Carna Biosciences) and 100 nM FITC-labeled histone H3 peptide were reacted in a reaction buffer (20 mM HEPES, 0.01% Tween-20, 0.3 mM MgCl2, 2 mM dithiothreitol, 50 micro-M ATP, pH 7.4) at room temperature for 1 hour. The reaction was stopped by the addition of three fold assay volume of progressive binding solution. Following 0.5 hour incubation at room temperature. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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