Detailed information for compound 39848

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 583.458 | Formula: C27H32Cl2N2O8--
  • H donors: 2 H acceptors: 2 LogP: 3.37 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(cc(c1O)OC)[C@@H]1[C@@H]2C(=O)OC[C@@H]2[C@H](c2c1cc1OCOc1c2)NCCN1CCOCC1.[Cl-].[Cl-]
  • InChi: 1S/C27H32N2O8.2ClH/c1-32-21-9-15(10-22(33-2)26(21)30)23-16-11-19-20(37-14-36-19)12-17(16)25(18-13-35-27(31)24(18)23)28-3-4-29-5-7-34-8-6-29;;/h9-12,18,23-25,28,30H,3-8,13-14H2,1-2H3;2*1H/p-2/t18-,23+,24-,25+;;/m0../s1
  • InChiKey: OHDDQCDVFKEWQK-HVXWUDJASA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0025 0.0015 0.0049
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0025 0.0015 0.0049
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0039 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0031 0.0033 0.0033
Brugia malayi Trypsin-like protease protein 5 0.021 0.056 0.056
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0129 0.032 0.032
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0037 0.0051 0.1245
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0025 0.0015 0.0037
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0073 0.0434
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0035 0.0035
Echinococcus granulosus cathepsin l1 0.0024 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Onchocerca volvulus 0.0212 0.0567 0.1753
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.0299 0.0823 0.0823
Schistosoma mansoni histamine h1 receptor 0.0032 0.0035 0.0088
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0038 0.0054 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0305 0.0841 0.3905
Echinococcus multilocularis neurogenic locus notch protein 4 0.0157 0.0404 0.0853
Loa Loa (eye worm) serotonin transporter b 0.0238 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0037 0.0051 0.0248
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0035 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0026 0.0016 0.0125
Mycobacterium ulcerans hypothetical protein 0.021 0.056 0.4332
Brugia malayi beta-lactamase family protein 0.004 0.0059 0.0059
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0059 0.0233
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0058 0.0113 0.0239
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Echinococcus multilocularis thioredoxin glutathione reductase 0.0407 0.1143 0.2414
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0103 0.0245 0.0517
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.004 0.0059 0.0059
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0058 0.0123
Loa Loa (eye worm) hypothetical protein 0.174 0.5082 0.5082
Brugia malayi G-protein coupled receptor 0.0032 0.0035 0.0035
Loa Loa (eye worm) histone methyltransferase 0.0042 0.0065 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0004 0.0014
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0007 0.0207
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0026 0.0016 0.0054
Entamoeba histolytica hypothetical protein 0.0142 0.0361 0.2019
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0928 0.2683 0.8976
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0044 0.0044
Onchocerca volvulus 0.0027 0.002 0.0062
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0407 0.1143 0.3823
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0037 0.0051 0.0192
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0129 0.032 0.032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0052 0.0111
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0073 0.0154
Mycobacterium tuberculosis Conserved protein 0.004 0.0059 0.0199
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0035 0.0088
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.021 0.056 0.1394
Loa Loa (eye worm) hypothetical protein 0.0045 0.0075 0.0075
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0037 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Treponema pallidum thioredoxin reductase (trxB) 0.0037 0.0051 0.0682
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0094 0.0094
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0094 0.0199
Echinococcus granulosus intermediate filament protein 0.0111 0.0269 0.0671
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0141 0.0357 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0027 0.002 0.002
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0004 0.0032
Brugia malayi Melatonin receptor type 1A 0.0032 0.0035 0.0035
Echinococcus multilocularis serotonin receptor 0.0165 0.0427 0.0903
Brugia malayi Cathepsin L-like precursor 0.0035 0.0044 0.0044
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0179 0.0179
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.017 0.036
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0025 0.0015 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0058 0.0145
Brugia malayi CHD4 protein 0.0021 0.0002 0.0002
Brugia malayi hypothetical protein 0.0451 0.1274 0.1274
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0094 0.0235
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0037 0.0051 0.1245
Schistosoma mansoni nuclear receptor 0.0033 0.0039 0.0098
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0035 0.0088
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0267 0.0728 0.2437
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1032 0.2989 1
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0035 0.0088
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.006 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Onchocerca volvulus 0.0032 0.0035 0.0109
Entamoeba histolytica hypothetical protein 0.0142 0.0361 0.2019
Echinococcus granulosus transmembrane protease serine 3 0.021 0.056 0.1394
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0052 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Echinococcus granulosus nAChR subunit 0.0058 0.0113 0.0281
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.015 0.0317
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0025 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.015 0.0317
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0044 0.0044
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.006 0.0149
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0035 0.0044 0.0137
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0129 0.032 0.0798
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0025 0.0015 0.0049
Loa Loa (eye worm) hypothetical protein 0.1114 0.3231 0.3231
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0035 0.0088
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0004 0.0014
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0059 0.0059
Plasmodium vivax amine transporter, putative 0.004 0.006 0.0357
Loa Loa (eye worm) hypothetical protein 0.0165 0.0427 0.0427
Schistosoma mansoni rab6-interacting 0.0058 0.0112 0.0279
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0035 0.0075
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0141 0.0357 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.3404 1 1
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Loa Loa (eye worm) hypothetical protein 0.0165 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0109 0.0263 0.0263
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.0143 0.0627
Brugia malayi Serotonin receptor 0.0032 0.0035 0.0035
Brugia malayi Cation transporter family protein 0.0058 0.0113 0.0113
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0052 0.0199
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0044 0.0137
Schistosoma mansoni neurotransmitter gated ion channel 0.0027 0.002 0.005
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0007 0.0007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0059 0.0199
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0037 0.0051 0.0192
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0052 0.013
Plasmodium falciparum LCCL domain-containing protein 0.0058 0.0112 0.0668
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0027 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.0656 0.1386
Brugia malayi latrophilin 2 splice variant baaae 0.0204 0.0544 0.0544
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0025 0.0015 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0129 0.032 0.032
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0044 0.011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0094 0.022 0.0547
Brugia malayi G protein-coupled receptor 0.0032 0.0035 0.0035
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.006 0.0127
Treponema pallidum gamma-glutamyl phosphate reductase 0.0025 0.0015 0.0114
Brugia malayi G-protein coupled receptor 0.0032 0.0035 0.0035
Onchocerca volvulus 0.0032 0.0035 0.0109
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0052 0.013
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0058 0.0113 0.0281
Mycobacterium ulcerans Type I modular polyketide synthase 0.0026 0.0016 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0037 0.0051 0.0047
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0035 0.0075
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.015 0.0374
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0052 0.013
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0011 0.0024
Schistosoma mansoni hypothetical protein 0.0049 0.0086 0.0215
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0035 0.0075
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0035 0.0109
Echinococcus granulosus transcription factor Dp 1 0.0044 0.007 0.0175
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0094 0.022 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0199
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0116 0.0284 0.0707
Schistosoma mansoni amine GPCR 0.0032 0.0035 0.0088
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0094 0.022 0.0464
Brugia malayi PHD-finger family protein 0.0037 0.0049 0.0049
Trypanosoma cruzi major cysteine proteinase, putative 0.0105 0.0252 0.0252
Schistosoma mansoni hypothetical protein 0.0025 0.0015 0.0037
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0035 0.0075
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Loa Loa (eye worm) GABA receptor subunit 0.0031 0.0033 0.0033
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0035 0.0088
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0238 0.0645 0.0645
Schistosoma mansoni cpg binding protein 0.0135 0.0339 0.0843
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0274 0.075 0.075
Plasmodium falciparum importin beta, putative 0.0061 0.012 0.0718
Echinococcus granulosus g protein coupled receptor 0.0032 0.0035 0.0088
Brugia malayi putative neuropeptide receptor 0.0032 0.0035 0.0035
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.0059 0.0059
Brugia malayi hypothetical protein 0.0242 0.0656 0.0656
Toxoplasma gondii PAN domain-containing protein 0.0212 0.0567 0.167
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Brugia malayi Calcium binding EGF domain containing protein 0.0157 0.0404 0.0404
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0026 0.0016 0.0016
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0037 0.0051 0.0051
Echinococcus granulosus Polycystic kidney disease protein 0.0058 0.0112 0.0279
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0039 0.0039
Schistosoma mansoni amine GPCR 0.0032 0.0035 0.0088
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0044 0.0264
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0165 0.016
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0004 0.0014
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0086 0.0086
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0035 0.0075
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0052 0.013
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0035 0.0088
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0031 0.0033 0.0083
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0025 0.0015 0.0015
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0037 0.0051 0.0192
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.021 0.056 0.1394
Brugia malayi cytochrome P450 0.0022 0.0004 0.0004
Loa Loa (eye worm) PAN domain-containing protein 0.0212 0.0567 0.0566
Treponema pallidum oxidoreductase 0.0037 0.0051 0.0682
Onchocerca volvulus 0.0035 0.0044 0.0137
Onchocerca volvulus 0.021 0.056 0.1732
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0039 0.0039
Schistosoma mansoni cpg binding protein 0.0135 0.0339 0.0843
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.015 0.0374
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.006 0.0127
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0043 0.009
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0052 0.0111
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0027 0.002 0.005
Onchocerca volvulus 0.0212 0.0567 0.1753
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.006 0.006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0058 0.0113 0.0113
Loa Loa (eye worm) fatty acid synthase 0.0025 0.0015 0.0015
Echinococcus multilocularis glutamate synthase 0.0037 0.0051 0.0108
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0058 0.0113 0.0113
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0037 0.0051 0.015
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0039 0.0098
Loa Loa (eye worm) PAN domain-containing protein 0.0212 0.0567 0.0566
Mycobacterium tuberculosis Conserved protein 0.004 0.0059 0.0199
Loa Loa (eye worm) Notch2 0.0157 0.0404 0.0404
Schistosoma mansoni acetylcholine receptor subunit beta 0.0027 0.002 0.005
Onchocerca volvulus 0.0058 0.0113 0.035
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0141 0.0357 0.2129
Echinococcus multilocularis glycoprotein Antigen 5 0.06 0.1713 0.3617
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0039 0.0098
Loa Loa (eye worm) notch protein 0.0157 0.0404 0.0404
Schistosoma mansoni lipoxygenase 0.0182 0.0479 0.1192
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0037 0.0051 0.017
Mycobacterium ulcerans polyketide synthase 0.0027 0.0021 0.0161
Schistosoma mansoni septate junction protein 0.0157 0.0404 0.1006
Echinococcus multilocularis chromobox protein 1 0.007 0.0148 0.0312
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0035 0.0088
Echinococcus multilocularis protein jagged 1 0.0157 0.0404 0.0853
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Brugia malayi Protein kinase domain containing protein 0.0588 0.1677 0.1677
Brugia malayi Cation transporter family protein 0.0058 0.0113 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0058 0.0145
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.001 0.0025
Onchocerca volvulus 0.0212 0.0567 0.1753
Leishmania major cathepsin L-like protease 0.0035 0.0044 0.0044
Mycobacterium tuberculosis Probable thioesterase TesA 0.0021 0.0004 0.0012
Schistosoma mansoni Smad4 0.0024 0.0011 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0004 0.0014
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0043 0.0106
Echinococcus granulosus cathepsin l1 0.0035 0.0044 0.011
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0039 0.0098
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0035 0.0035
Toxoplasma gondii microneme protein MIC4 0.0212 0.0567 0.167
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Leishmania major hypothetical protein, conserved 0.004 0.0059 0.0059
Trypanosoma brucei NADH dehydrogenase 0.0037 0.0051 0.0047
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0035 0.0088
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0052 0.0111
Brugia malayi ecdysone receptor 0.0033 0.0039 0.0039
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0299 0.0823 0.0823
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0058 0.0227
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0044 0.0044
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0065 0.0138
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0004 0.0014
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0037 0.0051 0.017
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0058 0.0113 0.0113
Trichomonas vaginalis chromobox protein, putative 0.007 0.0148 0.0646
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0496 0.1407 0.1407
Mycobacterium tuberculosis Probable reductase 0.0928 0.2683 0.8976
Loa Loa (eye worm) DR-78 0.0033 0.0039 0.0039
Brugia malayi Cathepsin L-like precursor 0.0024 0.001 0.001
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.006 0.0149
Schistosoma mansoni opsin-like receptor 0.0032 0.0035 0.0088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0058 0.0227
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Leishmania major cathepsin L-like protease 0.0035 0.0044 0.0044
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0004 0.0004
Brugia malayi hypothetical protein 0.0038 0.0051 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0287 0.0788 0.6099
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0094 0.0199
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0058 0.0113 0.0113
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0025 0.0015 0.0114
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0274 0.075 0.075
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0039 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Echinococcus multilocularis musashi 0.0111 0.0269 0.0569
Loa Loa (eye worm) CXXC zinc finger family protein 0.0125 0.0311 0.0311
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.015 0.0374
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0058 0.0113 0.0113
Loa Loa (eye worm) PAN domain-containing protein 0.0212 0.0567 0.0566
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0037 0.0051 0.0127
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Echinococcus granulosus protein jagged 2 0.0157 0.0404 0.1006
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0111 0.0269 0.0269
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.006 0.0149
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Brugia malayi Pre-SET motif family protein 0.0654 0.1872 0.1872
Loa Loa (eye worm) hypothetical protein 0.0274 0.075 0.075
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0224 0.0662
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0451 0.1274 0.1274
Brugia malayi Nuclear hormone receptor-like 1 0.0539 0.1534 0.1534
Echinococcus granulosus somatostatin receptor 0.0032 0.0035 0.0088
Toxoplasma gondii aldehyde dehydrogenase 0.0457 0.1292 0.381
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0058 0.0113 0.0239
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0058 0.0227
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0025 0.0015 0.0114
Brugia malayi GCC2 and GCC3 family protein 0.0157 0.0404 0.0404
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0019 0.0044
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0035 0.0088
Brugia malayi Dopamine receptor 0.0032 0.0035 0.0035
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0116 0.0116
Brugia malayi Trypsin family protein 0.021 0.056 0.056
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Schistosoma mansoni opsin-like receptor 0.0032 0.0035 0.0088
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0035 0.0075
Schistosoma mansoni disulfide oxidoreductase 0.0037 0.0051 0.0127
Echinococcus multilocularis Tolloid protein 1 0.0274 0.075 0.1585
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.006 0.0149
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) cytochrome P450 0.0022 0.0004 0.0004
Brugia malayi RNA, U transporter 1 0.0173 0.0452 0.0452
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0059 0.0233
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0173 0.1034
Loa Loa (eye worm) hypothetical protein 0.3404 1 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0173 0.0511
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0588 0.1677 1
Giardia lamblia Kinase, PLK 0.0616 0.176 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Loa Loa (eye worm) TK/ROR protein kinase 0.0588 0.1677 0.1677
Mycobacterium ulcerans thioesterase 0.0021 0.0004 0.0027
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0058 0.0113 0.0239
Echinococcus multilocularis glycine receptor subunit beta 0.0058 0.0113 0.0239
Entamoeba histolytica hypothetical protein 0.0142 0.0361 0.2019
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0103 0.0245 0.0517
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Brugia malayi hypothetical protein 0.0027 0.002 0.002
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0027 0.002 0.002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0039 0.0122
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Onchocerca volvulus 0.0212 0.0567 0.1753
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0016 0.004
Brugia malayi Cytochrome P450 family protein 0.0061 0.012 0.0119
Schistosoma mansoni importin beta-1 0.0061 0.012 0.03
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Brugia malayi Thioredoxin reductase 0.0407 0.1143 0.1143
Toxoplasma gondii PAN/Apple domain-containing protein 0.0212 0.0567 0.167
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Echinococcus multilocularis notch 0.0157 0.0404 0.0853
Loa Loa (eye worm) hypothetical protein 0.0111 0.0269 0.0269
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0051 0.0152
Loa Loa (eye worm) hypothetical protein 0.0043 0.0068 0.0068
Mycobacterium ulcerans glutamate synthase subunit beta 0.0037 0.0051 0.0394
Onchocerca volvulus 0.0212 0.0567 0.1753
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0015 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0059 0.0233
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Brugia malayi Kringle domain containing protein 0.0588 0.1677 0.1677
Trichomonas vaginalis helicase, putative 0.0028 0.0024 0.0067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0035 0.0075
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0025 0.0015 0.0049
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) LGC-31 protein 0.0058 0.0113 0.0113
Schistosoma mansoni ran 0.0045 0.0073 0.0181
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0035 0.0088
Echinococcus multilocularis importin subunit beta 1 0.0061 0.012 0.0254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0058 0.0113 0.0113
Mycobacterium ulcerans hypothetical protein 0.0037 0.0051 0.0394
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.1992 0.4962
Schistosoma mansoni hypothetical protein 0.0037 0.0051 0.0127
Brugia malayi Pre-SET motif family protein 0.0096 0.0224 0.0224
Echinococcus granulosus serotonin receptor 0.0032 0.0035 0.0088
Brugia malayi Melibiase family protein 0.0069 0.0143 0.0143
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0027 0.002 0.005
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.002 0.0000037133 0.0000092482
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0004 0.0014
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0027 0.0021 0.0161
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0021 0.007
Echinococcus multilocularis lysine specific histone demethylase 1A 0.002 0.0000037133 0.0000078435
Brugia malayi neuropeptide F receptor 0.0032 0.0035 0.0035
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0052 0.0052
Onchocerca volvulus 0.0024 0.0011 0.0034
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0242 0.0656 0.0656
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0928 0.2683 0.8976
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0141 0.0357 0.0357
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.015 0.0317
Schistosoma mansoni hypothetical protein 0.0022 0.0004 0.001
Schistosoma mansoni intermediate filament proteins 0.0111 0.0269 0.0671
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0004 0.0014
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0035 0.0043 0.009
Plasmodium vivax vivapain-2 0.0035 0.0044 0.0264
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0037 0.0051 0.0051
Brugia malayi Bromodomain containing protein 0.0045 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0002 0.0002
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0141 0.0357 0.2763
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Schistosoma mansoni glutamate synthase 0.0037 0.0051 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0025 0.0015 0.0011
Loa Loa (eye worm) programmed cell death 8 0.0037 0.0051 0.0051
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0058 0.0113 0.0281
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0025 0.0015 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0007 0.0003
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0027 0.002 0.002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0141 0.0357 0.2763
Plasmodium vivax vivapain-2 0.0035 0.0044 0.0264
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0058 0.0113 0.0113
Schistosoma mansoni opsin-like receptor 0.0032 0.0035 0.0088
Schistosoma mansoni hypothetical protein 0.1379 0.4015 1
Echinococcus multilocularis transmembrane protease serine 3 0.021 0.056 0.1182
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0025 0.0015 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0148 0.0378 0.0941
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0025 0.0015 0.0042
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Onchocerca volvulus 0.0032 0.0035 0.0109
Schistosoma mansoni notch 0.0157 0.0404 0.1006
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0026 0.0016 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0058 0.0113 0.0281
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.015 0.0317
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Schistosoma mansoni cpg binding protein 0.0125 0.0311 0.0774
Brugia malayi Dopamine receptor protein 2 0.0032 0.0035 0.0035
Brugia malayi hypothetical protein 0.0058 0.0112 0.0112
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0058 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0004 0.0032
Echinococcus granulosus GPCR family 2 0.0094 0.022 0.0547
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0037 0.0051 0.0047
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Plasmodium vivax hypothetical protein, conserved 0.004 0.0059 0.0355
Schistosoma mansoni coup transcription factor 0.0071 0.015 0.0374
Echinococcus granulosus neural cadherin 0.0157 0.0404 0.1006
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.015 0.0374
Loa Loa (eye worm) norepinephrine transporter 0.0238 0.0645 0.0645
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Schistosoma mansoni cytochrome P450 0.0022 0.0004 0.001
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.006 0.1679
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0037 0.0051 0.0207
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0037 0.0051 0.0051
Echinococcus multilocularis somatostatin receptor 0.0032 0.0035 0.0075
Schistosoma mansoni amine GPCR 0.0032 0.0035 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.015 0.015
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0024 0.0011 0.0011
Brugia malayi aldehyde dehydrogenase 0.0025 0.0015 0.0015
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0037 0.0051 0.0108
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0496 0.1407 0.6562
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0059 0.0199
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0025 0.0015 0.0043
Toxoplasma gondii PAN domain-containing protein 0.1168 0.3391 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0165 0.0896
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0021 0.0004 0.0012
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0037 0.0051 0.0192
Loa Loa (eye worm) transcription factor SMAD2 0.0353 0.0983 0.0983
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0004 0.0032
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0368 0.1026 0.4776
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0044 0.0094
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0141 0.0357 0.2129
Entamoeba histolytica Ran family GTPase 0.0045 0.0073 0.0373
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0037 0.0051 0.0192
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0116 0.0901
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Echinococcus granulosus g protein coupled receptor 0.0032 0.0035 0.0088
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0058 0.0113 0.0281
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0037 0.0051 0.017
Schistosoma mansoni Lysine-specific histone demethylase 1 0.002 0.0000037133 0.0000092482
Entamoeba histolytica thioredoxin reductase, putative 0.0037 0.0051 0.0248
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0032 0.0035 0.0088
Echinococcus multilocularis Smad4 0.0024 0.0011 0.0024
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0026 0.0016 0.0054
Echinococcus granulosus neurogenic locus notch protein 4 0.0157 0.0404 0.1006
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0015 0.0042
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3404 1 1
Echinococcus multilocularis RUN 0.0058 0.0112 0.0237
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0165 0.0348
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0059 0.0199
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0004 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0004 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0037 0.0051 0.0248
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0052 0.013
Onchocerca volvulus 0.0212 0.0567 0.1753
Schistosoma mansoni neuropeptide receptor 0.0032 0.0035 0.0088
Entamoeba histolytica cysteine protease, putative 0.0035 0.0044 0.0211
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.006 0.0149
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Echinococcus granulosus Smad4 0.0024 0.0011 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0035 0.0088
Echinococcus granulosus hypothetical protein 0.0715 0.2055 0.5117
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0004 0.0014
Schistosoma mansoni smad1 5 8 and 0.0024 0.0011 0.0028
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0025 0.0015 0.0043
Leishmania major cathepsin L-like protease 0.0134 0.0337 0.0337
Brugia malayi Smad1 0.0024 0.0011 0.0011
Echinococcus granulosus serotonin transporter 0.0238 0.0645 0.1606
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0058 0.0113 0.0281
Loa Loa (eye worm) hypothetical protein 0.0588 0.1677 0.1677
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0025 0.0015 0.0011
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0058 0.0113 0.0281
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0066 0.0164
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0094 0.022 0.0547
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.075 0.075
Echinococcus multilocularis thyroid hormone receptor alpha 0.0318 0.0881 0.1861
Trypanosoma cruzi polo-like protein kinase, putative 0.0616 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0033 0.0033
Brugia malayi hypothetical protein 0.0038 0.0052 0.0052
Onchocerca volvulus 0.0212 0.0567 0.1753
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0051 0.0128
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0039 0.0098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Loa Loa (eye worm) cysteine protease 0.0035 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0307 0.0847 0.0847
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0035 0.0088
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0051 0.0306
Mycobacterium ulcerans thioesterase TesA 0.0021 0.0004 0.0027
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1032 0.2989 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0094 0.022 0.0464
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0238 0.0645 0.1606
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0035 0.0088
Toxoplasma gondii ABC1 family protein 0.004 0.0059 0.0175
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0000037133 0.0000092482
Loa Loa (eye worm) hypothetical protein 0.0238 0.0645 0.0645
Schistosoma mansoni hypothetical protein 0.0094 0.022 0.0547
Schistosoma mansoni kinase 0.0313 0.0865 0.2155
Trypanosoma cruzi NADH dehydrogenase, putative 0.0037 0.0051 0.0051
Echinococcus granulosus importin subunit beta 1 0.0061 0.012 0.03
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0212 0.0567 0.167
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0038 0.0051 0.0109
Echinococcus multilocularis tissue type plasminogen activator 0.0588 0.1677 0.3542
Toxoplasma gondii type I fatty acid synthase, putative 0.0027 0.0021 0.0061
Brugia malayi ORL1-like opioid receptor 0.0032 0.0035 0.0035
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0025 0.0015 0.0049
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.006 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0307 0.0847 0.0847
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0616 0.176 0.4384
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0035 0.0075
Giardia lamblia Rab geranylgeranyltransferase 0.0129 0.032 0.1752
Echinococcus multilocularis sex peptide receptor 0.0032 0.0035 0.0075
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0928 0.2683 0.8976
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Onchocerca volvulus 0.0032 0.0035 0.0109
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0025 0.0015 0.0031
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0165 0.041
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0037 0.0051 0.015
Loa Loa (eye worm) thioredoxin reductase 0.0407 0.1143 0.1143
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.015 0.0374
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0141 0.0357 0.2763
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0015 0.0015
Brugia malayi hypothetical protein 0.0058 0.0112 0.0112
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0035 0.0035
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0116 0.029
Loa Loa (eye worm) ctsf protein 0.0035 0.0044 0.0044
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0035 0.0088
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0157 0.0404 0.125
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0116 0.029
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Echinococcus multilocularis nAChR subunit 0.0058 0.0113 0.0239
Onchocerca volvulus 0.0157 0.0404 0.125
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0035 0.0075
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0004 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Loa Loa (eye worm) hypothetical protein 0.0238 0.0645 0.0645
Brugia malayi Trypsin family protein 0.021 0.056 0.056
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0035 0.0044 0.0137
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0052 0.013
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0337 0.0337
Schistosoma mansoni amine GPCR 0.0032 0.0035 0.0088
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0129 0.032 0.032
Echinococcus granulosus muscleblind protein 0.0307 0.0847 0.2111
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0037 0.0051 0.015
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0015 0.0037
Echinococcus multilocularis slit 2 protein 0.0157 0.0404 0.0853
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0004 0.0014
Brugia malayi nuclear hormone receptor 0.0071 0.015 0.015
Brugia malayi Fibulin-1 precursor 0.0274 0.075 0.075
Onchocerca volvulus 0.0744 0.2139 0.6619
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.021 0.056 0.1394
Echinococcus multilocularis serotonin transporter 0.0238 0.0645 0.1362
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0044 0.011
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0245 0.061
Plasmodium falciparum transporter, putative 0.004 0.006 0.0357
Toxoplasma gondii cathepsin CPL 0.0035 0.0044 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0035 0.0035
Echinococcus granulosus expressed protein 0.0738 0.2121 0.5283
Toxoplasma gondii microneme protein, putative 0.0212 0.0567 0.167
Brugia malayi hypothetical protein 0.0038 0.0051 0.0051
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0016 0.0034
Giardia lamblia Thioredoxin reductase 0.0037 0.0051 0.0207
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0049 0.0086 0.0267
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0037 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0173 0.1034
Trichomonas vaginalis glutathione reductase, putative 0.0141 0.0357 0.1631
Brugia malayi MH2 domain containing protein 0.0024 0.0011 0.0011
Onchocerca volvulus 0.004 0.006 0.0185
Trichomonas vaginalis glutamate synthase, putative 0.0037 0.0051 0.0192
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0058 0.0227
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.006 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0224 0.0559
Loa Loa (eye worm) hypothetical protein 0.0058 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.021 0.056 0.056
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0496 0.1407 0.1407
Loa Loa (eye worm) hypothetical protein 0.004 0.0059 0.0059
Onchocerca volvulus 0.0108 0.0258 0.0799
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0051 0.0047
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0035 0.0088
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0116 0.0116
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0021 0.0001 0.001
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0035 0.0035
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0058 0.0113 0.0281
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0199
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0143 0.0357
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0928 0.2683 0.8976
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0027 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0037 0.0051 0.017
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0058 0.0113 0.0113
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0044 0.011
Schistosoma mansoni hypothetical protein 0.0588 0.1677 0.4176
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0037 0.0051 0.1245
Toxoplasma gondii PAN domain-containing protein 0.0212 0.0567 0.167
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0052 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0039 0.0083
Toxoplasma gondii NADPH-glutathione reductase 0.0141 0.0357 0.1053
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0025 0.0015 0.0037
Loa Loa (eye worm) hypothetical protein 0.0094 0.022 0.022
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0011 0.0028
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Schistosoma mansoni neuropeptide receptor 0.0032 0.0035 0.0088
Schistosoma mansoni nAChR subunit 0.0027 0.002 0.005
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0245 0.061
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0037 0.0051 0.0127
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0052 0.013
Schistosoma mansoni smad 0.0024 0.0011 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0199
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0103 0.0245 0.061
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0004 0.0032
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.006 0.0149
Onchocerca volvulus 0.0031 0.0031 0.0097
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0004 0.0032
Plasmodium falciparum glutathione reductase 0.0407 0.1143 0.6815
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0059 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Onchocerca volvulus 0.0058 0.0113 0.035
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0073 0.0069
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0165 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0199
Onchocerca volvulus 0.0032 0.0035 0.0109
Schistosoma mansoni laminin gamma-3 chain 0.0157 0.0404 0.1006
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.015 0.015
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0058 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.015 0.0374
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0029 0.0029
Onchocerca volvulus 0.0024 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.004 0.0059 0.0059
Onchocerca volvulus Neurogenic locus notch homolog 0.0157 0.0404 0.1251
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0049 0.0084 0.0084
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0007 0.0044
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0028 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0141 0.0357 1
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0129 0.032 0.0317
Brugia malayi Cytochrome P450 family protein 0.003 0.0029 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0011 0.0011
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0496 0.1407 0.6562
Onchocerca volvulus 0.021 0.056 0.1732
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0056 0.0219
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0104 0.0246 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0025 0.0015 0.0114
Entamoeba histolytica hypothetical protein 0.0142 0.0361 0.2019
Echinococcus multilocularis conserved hypothetical protein 0.0683 0.196 0.4139
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0052 0.0111
Schistosoma mansoni notch 0.0157 0.0404 0.1007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.006 0.0149
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0015 0.0042
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0061 0.012 0.012
Echinococcus granulosus protein jagged 1 0.0157 0.0404 0.1006
Mycobacterium leprae Probable lipase LipE 0.004 0.0059 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.015 0.015
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0044 0.0044
Brugia malayi hypothetical protein 0.0142 0.0361 0.0361
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0004 0.0014
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0037 0.0051 0.0047
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0021 0.0161
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0004 0.0014
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0027 0.0021 0.007
Echinococcus granulosus g protein coupled receptor 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0032 0.0035 0.0109
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0112 0.0279
Schistosoma mansoni hypothetical protein 0.0094 0.022 0.0547
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0025 0.0015 0.0015
Mycobacterium ulcerans dehydrogenase 0.0037 0.0051 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.015 0.015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.015 0.0374
Schistosoma mansoni hypothetical protein 0.0142 0.0361 0.09
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0037 0.0051 0.0108
Echinococcus multilocularis fibropellin Ia 0.0157 0.0404 0.0853
Brugia malayi Cation transporter family protein 0.0058 0.0113 0.0113
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0204 0.0544 0.0544
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.006 0.006
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0015 0.0015
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0007 0.0057
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0037 0.0051 0.0051
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.015 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0058 0.0145
Mycobacterium ulcerans aldehyde dehydrogenase 0.0457 0.1292 1
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Echinococcus multilocularis snurportin 1 0.065 0.1862 0.3934
Mycobacterium ulcerans ferredoxin reductase 0.0037 0.0051 0.0394
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0496 0.1407 0.2971
Onchocerca volvulus Fatty acid synthase homolog 0.0046 0.0077 0.0238
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.006 0.0149
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0025 0.0015 0.0114
Brugia malayi nuclear receptor RXR 0.0033 0.0039 0.0039
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Onchocerca volvulus 0.0037 0.0051 0.0158
Trichomonas vaginalis apoptosis inducing factor, putative 0.0037 0.0051 0.0192
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.015 0.0465
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0037 0.0051 0.017
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0129 0.032 0.032
Plasmodium vivax thioredoxin reductase, putative 0.0407 0.1143 0.6815
Loa Loa (eye worm) solute carrier family 6 member 4 0.0238 0.0645 0.0645
Echinococcus multilocularis chromobox protein 1 0.007 0.0148 0.0312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0112 0.0237
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0496 0.1407 0.7983
Echinococcus multilocularis neurogenic locus protein delta 0.0157 0.0404 0.0853
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.006 0.0177
Schistosoma mansoni smad1 5 8 and 0.0024 0.0011 0.0028
Brugia malayi MH1 domain containing protein 0.0024 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0337 0.0337
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0058 0.0113 0.0113
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0052 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Schistosoma mansoni chromobox protein 0.007 0.0148 0.0367
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0037 0.0051 0.0304
Echinococcus multilocularis nAChR subunit 0.0031 0.0033 0.007
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0037 0.0051 0.0304
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0038 0.0054 0.0179
Onchocerca volvulus 0.0033 0.0039 0.0122
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0004 0.0032
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0037 0.0051 0.017
Mycobacterium leprae putative cytochrome p450 0.0022 0.0004 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0116 0.0901
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0044 0.0094
Echinococcus granulosus tissue type plasminogen activator 0.0588 0.1677 0.4176
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.021 0.056 0.056
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0044 0.0094
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0073 0.0333
Onchocerca volvulus 0.0035 0.0044 0.0137
Brugia malayi Augmenter of liver regeneration 0.0038 0.0051 0.0051
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0029 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0015 0.0015
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0058 0.0113 0.0113
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0037 0.0051 0.0304
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.0052 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Echinococcus multilocularis fibrillin 1 0.0274 0.075 0.1585
Onchocerca volvulus 0.004 0.0059 0.0184
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0059 0.0059
Echinococcus granulosus fibropellin Ia 0.0157 0.0404 0.1006
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0037 0.0051 0.0051
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0051 0.0051
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0141 0.0357 0.0357
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0148 0.0147
Brugia malayi AKH receptor 0.0032 0.0035 0.0035
Brugia malayi Doublecortin family protein 0.0058 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1114 0.3231 0.8047
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0274 0.075 0.075
Schistosoma mansoni lamin 0.0111 0.0269 0.0671
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0037 0.0051 0.015
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0059 0.0148
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0035 0.0088
Toxoplasma gondii calcium binding egf domain-containing protein 0.0274 0.075 0.2213
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0052 0.013
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0129 0.032 0.1459
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0037 0.0051 0.017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Schistosoma mansoni biogenic amine receptor 0.0032 0.0035 0.0088
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0037 0.0051 0.0192
Onchocerca volvulus 0.1114 0.3231 1
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0025 0.0015 0.0015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.015 0.015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0032 0.0035 0.0035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0081 0.0179 0.0179
Onchocerca volvulus 0.0058 0.0112 0.0347
Onchocerca volvulus 0.0157 0.0404 0.125
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.001 0.0015
Schistosoma mansoni amine oxidase 0.002 0.0000037133 0.0000092482
Giardia lamblia High cysteine protein 0.0157 0.0404 0.223
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0039 0.0098
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0274 0.075 0.075
Echinococcus granulosus neurogenic locus notch protein 0.0157 0.0404 0.1006
Toxoplasma gondii thioredoxin reductase 0.0407 0.1143 0.3369
Onchocerca volvulus 0.0032 0.0035 0.0109
Onchocerca volvulus 0.0031 0.0033 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.021 0.056 0.1182
Echinococcus granulosus sex peptide receptor 0.0032 0.0035 0.0088
Echinococcus granulosus geminin 0.1379 0.4015 1
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0037 0.0051 0.017
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0025 0.0015 0.0049
Leishmania major GTP-binding protein, putative 0.0045 0.0073 0.0073
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0035 0.0075
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0052 0.0052
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.021 0.056 0.056
Loa Loa (eye worm) hypothetical protein 0.0496 0.1407 0.1407
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0073 0.0181
Echinococcus multilocularis cysteine protease 0.0035 0.0044 0.0094
Mycobacterium leprae Polyketide synthase Pks13 0.0038 0.0054 0.0179
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0037 0.0051 0.0394
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.06 0.1713 0.4265
Treponema pallidum NADH oxidase 0.0141 0.0357 0.5483
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0035 0.0088
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0058 0.0113 0.0113
Plasmodium falciparum cysteine repeat modular protein 1 0.0588 0.1677 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.021 0.056 0.056
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0224 0.0474
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0093 0.0093
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0035 0.0088
Brugia malayi nuclear receptor NHR-88 0.0071 0.015 0.015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0035 0.0088
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0004 0.0032
Echinococcus multilocularis neurogenic locus notch protein 0.0157 0.0404 0.0853
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0058 0.0113 0.0239
Schistosoma mansoni nAChR subunit 0.0027 0.002 0.005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0112 0.0112
Onchocerca volvulus 0.004 0.0059 0.0184
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0025 0.0015 0.0114
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0059 0.0199
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Schistosoma mansoni aldehyde dehydrogenase 0.0457 0.1292 0.3218
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0044 0.0211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Entamoeba histolytica hypothetical protein 0.0038 0.0052 0.0256
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0043 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0199
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0274 0.075 0.075
Schistosoma mansoni notch 0.0157 0.0404 0.1006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0039 0.0083
Schistosoma mansoni cell polarity protein 0.0157 0.0404 0.1006
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.0117 0.0117
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0142 0.0361 0.0763
Leishmania major cytochrome p450-like protein 0.003 0.0029 0.0029
Mycobacterium ulcerans NADH dehydrogenase 0.0037 0.0051 0.0394
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0035 0.0088
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis neurogenic locus notch protein 0.0157 0.0404 0.0853
Schistosoma mansoni glutamate synthase 0.0037 0.0051 0.0127
Mycobacterium ulcerans Type I modular polyketide synthase 0.0026 0.0016 0.0125
Loa Loa (eye worm) trypsin family protein 0.021 0.056 0.056
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.021 0.056 0.1394
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.015 0.0374
Brugia malayi Calcitonin receptor-like protein seb-1 0.0299 0.0823 0.0823
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0027 0.002 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0015 0.0037
Brugia malayi hypothetical protein 0.0038 0.0052 0.0052
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0007 0.0025
Schistosoma mansoni glutamate synthase 0.0037 0.0051 0.0127
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0025 0.0015 0.0114
Echinococcus multilocularis Polycystic kidney disease protein 0.0058 0.0112 0.0237
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0616 0.176 0.176
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0037 0.0051 0.0248
Schistosoma mansoni transcription factor LCR-F1 0.0142 0.0361 0.09
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.015 0.015
Schistosoma mansoni zinc finger protein 0.0033 0.0039 0.0098
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0141 0.0357 0.2129
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.006 0.006
Plasmodium vivax glutathione reductase, putative 0.0407 0.1143 0.6815
Plasmodium falciparum glutathione reductase 0.0141 0.0357 0.2129
Mycobacterium ulcerans polyketide synthase Pks13 0.0038 0.0054 0.0415
Schistosoma mansoni hypothetical protein 0.1379 0.4015 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0066 0.0139
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.012 0.0119
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0039 0.0083
Echinococcus granulosus biogenic amine 5HT receptor 0.0165 0.0427 0.1064
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.015 0.015
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Brugia malayi Latrophilin receptor protein 2 0.0094 0.022 0.022
Trichomonas vaginalis mercuric reductase, putative 0.0141 0.0357 0.1631
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.015 0.015
Schistosoma mansoni polycystin 1-related 0.0058 0.0112 0.0279
Trypanosoma brucei hypothetical protein, conserved 0.0129 0.032 0.0317
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Loa Loa (eye worm) acetylcholine receptor protein 0.0027 0.002 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Echinococcus granulosus glutamate synthase 0.0037 0.0051 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0056 0.0219
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0039 0.0039
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0037 0.0051 0.0051
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0104 0.0246 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0039 0.0056 0.0056
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0052 0.013
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0037 0.0051 0.0394
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0013 0.0015
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0274 0.075 0.075
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0059 0.046
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0039 0.0098
Mycobacterium ulcerans lipase LipD 0.004 0.0059 0.046
Trypanosoma cruzi trypanothione reductase, putative 0.0141 0.0357 0.0357
Brugia malayi Muscleblind-like protein 0.0307 0.0847 0.0847
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0039 0.0098
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0116 0.0284 0.06
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Brugia malayi hypothetical protein 0.0033 0.0039 0.0039
Brugia malayi hypothetical protein 0.021 0.056 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.015 0.015
Brugia malayi beta-lactamase family protein 0.004 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0112 0.0279
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Schistosoma mansoni chromobox protein 0.007 0.0148 0.0367
Plasmodium vivax hypothetical protein, conserved 0.004 0.006 0.0357
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.015 0.0374
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0031
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0099 0.0247
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0021 0.0002 0.0005
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0031 0.0033 0.0083
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0035 0.0075
Schistosoma mansoni slit 0.0157 0.0404 0.1006
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0027 0.002 0.0042
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0021 0.0002 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0094 0.0235
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0027 0.002 0.0042
Toxoplasma gondii hypothetical protein 0.0212 0.0567 0.167
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.006 0.006
Brugia malayi Cytochrome P450 family protein 0.003 0.0029 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0011 0.0028
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0027 0.002 0.002
Onchocerca volvulus 0.004 0.006 0.0185
Schistosoma mansoni hypothetical protein 0.0094 0.022 0.0547
Brugia malayi cathepsin L-like precursor 0.0024 0.001 0.001
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0025 0.0015 0.0049
Onchocerca volvulus Arrow homolog 0.0274 0.075 0.2322
Brugia malayi hypothetical protein 0.0027 0.002 0.002
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0015 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0038 0.0052 0.0256
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0004
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0051 0.0051
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0165 0.0164
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0094 0.0235
Schistosoma mansoni hypothetical protein 0.021 0.056 0.1394
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0059 0.0148
Onchocerca volvulus 0.0035 0.0044 0.0137
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0245 0.061
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0035 0.0088
Schistosoma mansoni ran 0.0045 0.0073 0.0181
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0035 0.0075
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0287 0.0788 0.1664
Echinococcus granulosus glycine receptor subunit beta 0.0058 0.0113 0.0281
Brugia malayi MH1 domain containing protein 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0143 0.0357
Echinococcus granulosus microtubule associated protein 2 0.0694 0.1992 0.4962
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.015 0.015
Onchocerca volvulus 0.0058 0.0113 0.035
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0245 0.061
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Plasmodium falciparum thioredoxin reductase 0.0407 0.1143 0.6815
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0015 0.0042
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.015 0.0317
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0039 0.0083
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0037 0.0051 0.0394
Loa Loa (eye worm) PAN domain-containing protein 0.0212 0.0567 0.0566
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0035 0.0075
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0044 0.0094
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus granulosus chromobox protein 1 0.007 0.0148 0.0367
Toxoplasma gondii PAN domain-containing protein 0.1168 0.3391 1
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0035 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0013 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0457 0.1292 0.3218
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0037 0.0051 0.0192
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0141 0.0357 0.0889
Mycobacterium ulcerans monoxygenase 0.0037 0.0051 0.0394
Mycobacterium ulcerans aldehyde dehydrogenase 0.0457 0.1292 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Echinococcus multilocularis lamin 0.0111 0.0269 0.0569
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0044 0.011
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0025 0.0015 0.0049
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0025 0.0015 0.0114
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0025 0.0015 0.0031
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0004 0.0032
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0037 0.0051 0.0051
Echinococcus multilocularis lamin dm0 0.0111 0.0269 0.0569
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0027 0.0021 0.007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0744 0.2138 1
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0496 0.1407 0.8389
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis neural cadherin 0.0157 0.0404 0.0853
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0037 0.0051 0.0248
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.015 0.0465
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0058 0.0113 0.0239
Schistosoma mansoni hypothetical protein 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0032 0.0035 0.0109
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0004 0.0032
Schistosoma mansoni survival motor neuron protein 0.0049 0.0086 0.0215
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0141 0.0357 0.0754
Brugia malayi RE15519p 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0238 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0129 0.032 0.1911
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0052 0.013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Echinococcus granulosus slit 2 protein 0.0157 0.0404 0.1006
Echinococcus granulosus neuropeptide receptor 0.0032 0.0035 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0059 0.0059
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Toxoplasma gondii microneme protein MIC17A 0.0212 0.0567 0.167
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0073 0.0073
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0065 0.026
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Brugia malayi Serotonin receptor 0.0032 0.0035 0.0035
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0021 0.0002 0.0004
Echinococcus granulosus neuropeptide receptor 0.0032 0.0035 0.0088
Schistosoma mansoni loxhd1 0.0058 0.0112 0.0279
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0035 0.0075
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0052 0.0111
Trypanosoma brucei polo-like protein kinase 0.0616 0.176 0.1757
Loa Loa (eye worm) doublecortin family protein 0.0058 0.0112 0.0112
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.004 0.0085
Echinococcus granulosus snurportin 1 0.065 0.1862 0.4639
Brugia malayi Muscle positioning protein 4 0.0157 0.0404 0.0404
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.004 0.01
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0058 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) aldehyde dehydrogenase 0.0025 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0079 0.0173 0.0173
Echinococcus granulosus fmrfamide receptor 0.0032 0.0035 0.0088
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0052 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0059 0.046
Onchocerca volvulus 0.0588 0.1677 0.5189
Echinococcus granulosus zinc finger protein 0.003 0.003 0.0075
Onchocerca volvulus 0.0904 0.2612 0.8083
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0037 0.0051 0.0394
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0058 0.0113 0.0281
Brugia malayi larval opioid receptor 0.0032 0.0035 0.0035
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0457 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0141 0.0357 0.0357
Loa Loa (eye worm) CYP4Cod1 0.003 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Echinococcus multilocularis neurogenic locus protein delta 0.0157 0.0404 0.0853
Plasmodium falciparum thioredoxin reductase 0.0141 0.0357 0.2129
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0129 0.032 0.1911
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.015 0.015
Onchocerca volvulus 0.0048 0.0082 0.0254
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0035 0.0109
Toxoplasma gondii hypothetical protein 0.004 0.006 0.0177
Mycobacterium ulcerans Type I modular polyketide synthase 0.0026 0.0016 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0274 0.075 0.075
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0129 0.032 0.0317
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.015 0.015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0035 0.0075
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0052 0.013
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0004 0.0012
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0179 0.0445
Loa Loa (eye worm) ACC-1 protein 0.0058 0.0113 0.0113
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0035 0.0088
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0015 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0094 0.0235
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0039 0.0083
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Mycobacterium leprae conserved hypothetical protein 0.004 0.0059 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0044
Trichomonas vaginalis glutamate synthase, putative 0.0037 0.0051 0.0192
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0058 0.0113 0.0239
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0037 0.0051 0.0108
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.015 0.0374
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0051 0.0108
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.015 0.015
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0037 0.0051 0.0192
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0007 0.0044
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.021 0.056 0.056
Onchocerca volvulus 0.021 0.056 0.1732
Echinococcus multilocularis enteropeptidase 0.06 0.1713 0.3617
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0457 0.1292 0.4322
Brugia malayi hypothetical protein 0.0027 0.002 0.002
Onchocerca volvulus 0.0125 0.0311 0.0962
Loa Loa (eye worm) CHromoDomain protein family member 0.0021 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.015 0.015
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0025 0.0015 0.0043
Onchocerca volvulus 0.0451 0.1274 0.3942
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.021 0.056 0.056
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0035 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0052 0.0111
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0035 0.0075
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Trichomonas vaginalis ran, putative 0.0045 0.0073 0.0296
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1032 0.2989 1
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0004 0.001
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0007 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0588 0.1677 0.1677
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0654 0.1872 0.1872
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Brugia malayi intermediate filament protein 0.0111 0.0269 0.0269
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0058 0.0113 0.0281
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0457 0.1292 0.2729
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0027 0.0021 0.007
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0025 0.0015 0.0037
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0157 0.0404 0.0404
Onchocerca volvulus 0.0071 0.015 0.0465
Schistosoma mansoni thyroid hormone receptor 0.0318 0.0881 0.2194
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0142 0.0361 0.09
Trypanosoma cruzi hypothetical protein, conserved 0.0129 0.032 0.032
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.1114 0.3231 0.3231
Mycobacterium ulcerans aldehyde dehydrogenase 0.0025 0.0015 0.0114
Echinococcus multilocularis muscleblind protein 0.0307 0.0847 0.179
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.1992 0.4208
Schistosoma mansoni neuropeptide receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Giardia lamblia Rab geranylgeranyltransferase 0.0496 0.1407 0.7975
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0035 0.0075
Toxoplasma gondii hypothetical protein 0.0368 0.1026 0.3027
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0052
Toxoplasma gondii hypothetical protein 0.0212 0.0567 0.167
Schistosoma mansoni hypothetical protein 0.0094 0.022 0.0547
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0037 0.0051 0.0304
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0044 0.0264
Schistosoma mansoni glutamate receptor NMDA 0.0061 0.0119 0.0297
Brugia malayi hypothetical protein 0.0027 0.002 0.002
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0073 0.0073
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0025 0.0015 0.0043
Schistosoma mansoni smad1 5 8 and 0.0024 0.0011 0.0028
Schistosoma mansoni sulfide quinone reductase 0.0037 0.0051 0.0127
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0025 0.0015 0.0114
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0027 0.002 0.002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0039 0.0083
Onchocerca volvulus 0.0045 0.0072 0.0224
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0045 0.0112
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1114 0.3231 0.8047
Onchocerca volvulus 0.0212 0.0567 0.1753
Brugia malayi Cathepsin L-like precursor 0.0035 0.0044 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0269 0.0736 0.1834
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0059 0.0059
Echinococcus multilocularis cpg binding protein 0.0135 0.0339 0.0715
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0052 0.013
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0035 0.0088
Giardia lamblia Glutamate synthase 0.0037 0.0051 0.0207
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.021 0.056 0.1182
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0086 0.0359
Brugia malayi nuclear receptor NHR-88 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Echinococcus multilocularis protein jagged 1 0.0157 0.0404 0.0853
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.001
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0058 0.0113 0.0239
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0086 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Schistosoma mansoni sulfide quinone reductase 0.0037 0.0051 0.0127
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0035 0.0035
Echinococcus granulosus glycine receptor subunit alpha 1 0.0058 0.0113 0.0281
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.006 0.0177
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.006 0.0127
Onchocerca volvulus 0.0212 0.0567 0.1753
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Trypanosoma cruzi cruzipain precursor, putative 0.0134 0.0337 0.0337
Brugia malayi hypothetical protein 0.0051 0.0091 0.0091
Brugia malayi F/Y-rich N-terminus family protein 0.0044 0.007 0.007
Toxoplasma gondii calcium binding egf domain-containing protein 0.0274 0.075 0.2213
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0024 0.0011 0.0037
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0059 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0004 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0129 0.032 0.1786
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Echinococcus multilocularis Mastin 0.06 0.1713 0.3617
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.006 0.0177
Brugia malayi Cadherin domain containing protein 0.0157 0.0404 0.0404
Onchocerca volvulus Putative cubilin 0.0157 0.0404 0.125
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.006 0.0149
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0129 0.032 0.0798
Loa Loa (eye worm) intermediate filament protein 0.0111 0.0269 0.0269
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.015 0.0374
Echinococcus granulosus neurogenic locus notch protein 0.0157 0.0404 0.1006
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0496 0.1407 0.6562
Leishmania major cathepsin L-like protease 0.0134 0.0337 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0023 0.0059
Leishmania major hypothetical protein, conserved 0.0038 0.0051 0.0051
Onchocerca volvulus 0.004 0.0059 0.0184
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0059 0.0233
Brugia malayi nuclear receptor RXR 0.0038 0.0051 0.0051
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0004 0.0004
Schistosoma mansoni nuclear receptor 0.0033 0.0039 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0094 0.0235
Loa Loa (eye worm) hypothetical protein 0.0035 0.0044 0.0044
Loa Loa (eye worm) hepatopoietin HPO2 0.0038 0.0051 0.0051
Brugia malayi Cytochrome P450 family protein 0.0022 0.0004 0.0004
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.012 0.0355
Brugia malayi serine/threonine-protein kinase plk-2 0.0616 0.176 0.176
Loa Loa (eye worm) MH2 domain-containing protein 0.0353 0.0983 0.0983
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0059 0.0059
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0025 0.0015 0.0114
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0616 0.176 0.176
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0058 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0058 0.0113 0.0239
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0157 0.0404 0.1006
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0035 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0004 0.0014
Echinococcus multilocularis GPCR, family 2 0.0094 0.022 0.0464
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0011 0.0024
Plasmodium vivax importin-beta 2, putative 0.0061 0.012 0.0718
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0025 0.0015 0.0015
Schistosoma mansoni bromodomain containing protein 0.0082 0.0183 0.0455
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.006 0.0149
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0059 0.0199
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.015 0.0374
Brugia malayi follicle stimulating hormone receptor 0.0032 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0025 0.0015 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0199
Echinococcus granulosus cpg binding protein 0.0135 0.0339 0.0843
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) ACC-1 protein 0.0058 0.0113 0.0113
Trypanosoma brucei cytochrome P450, putative 0.003 0.0029 0.0025
Brugia malayi Trypsin family protein 0.1114 0.3231 0.3231
Brugia malayi CXXC zinc finger family protein 0.0125 0.0311 0.0311
Leishmania major importin beta-1 subunit, putative 0.0049 0.0086 0.0086
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0037 0.0051 0.0051
Toxoplasma gondii subtilisin SUB12 0.0212 0.0567 0.167
Echinococcus granulosus delta-like protein 1 0.0157 0.0404 0.1006
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0058 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Brugia malayi Cadherin domain containing protein 0.0157 0.0404 0.0404
Brugia malayi nuclear receptor NHR-67 0.0033 0.0039 0.0039
Echinococcus multilocularis protein jagged 2 0.0157 0.0404 0.0853
Brugia malayi Intermediate filament tail domain containing protein 0.0111 0.0269 0.0269
Brugia malayi beta-lactamase 0.004 0.0059 0.0059
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0037 0.0051 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0025 0.0015 0.0037
Echinococcus granulosus Tolloid protein 1 0.0274 0.075 0.1869
Plasmodium vivax SET domain protein, putative 0.0096 0.0224 0.1338
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0037 0.0051 0.0047
Brugia malayi Calcium binding EGF domain containing protein 0.0157 0.0404 0.0404
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0025 0.0015 0.0031
Onchocerca volvulus 0.0157 0.0404 0.125
Toxoplasma gondii PAN domain-containing protein 0.0212 0.0567 0.167
Toxoplasma gondii EGF family domain-containing protein 0.0157 0.0404 0.1191
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0035 0.0075
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.015 0.0374
Toxoplasma gondii hypothetical protein 0.0129 0.032 0.0945
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0039 0.0039
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0058 0.0113 0.0281
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.006 0.0149
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0037 0.0051 0.017
Echinococcus granulosus orexin receptor type 2 0.0032 0.0035 0.0088
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0141 0.0357 0.2129
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0004 0.0032
Toxoplasma gondii selenide, water dikinase 0.0037 0.0051 0.015
Onchocerca volvulus 0.0157 0.0404 0.125
Loa Loa (eye worm) fibroinase 0.0035 0.0044 0.0044
Onchocerca volvulus 0.021 0.056 0.1732
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0025 0.0014 0.0046
Toxoplasma gondii microneme protein MIC17C 0.0212 0.0567 0.167
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0011 0.0028
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0038 0.0051 0.0306
Schistosoma mansoni notch 0.0157 0.0404 0.1006
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0007 0.0057
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0141 0.0357 0.1194
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.012 0.0116
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0129 0.032 0.032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Plasmodium falciparum amino acid transporter, putative 0.004 0.006 0.0357
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0073 0.0434
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0039 0.0039
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0616 0.176 0.3718
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0035 0.0035
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.001
Onchocerca volvulus 0.0027 0.002 0.0062
Onchocerca volvulus 0.0035 0.0044 0.0137
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0025 0.0015 0.0049
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Echinococcus granulosus chromobox protein 1 0.007 0.0148 0.0367
Trypanosoma cruzi polo-like protein kinase, putative 0.0616 0.176 0.176
Brugia malayi PXA domain containing protein 0.0038 0.0052 0.0052
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0058 0.0113 0.0281
Brugia malayi MH2 domain containing protein 0.0024 0.0011 0.0011
Echinococcus multilocularis zinc finger protein 0.003 0.003 0.0063
Onchocerca volvulus 0.0033 0.0039 0.0122
Toxoplasma gondii Erv1 / Alr family protein 0.0038 0.0051 0.0152
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0058 0.0113 0.0281
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0052 0.013
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0141 0.0357 0.0353
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0058 0.0113 0.0239
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.015 0.0317
Leishmania major cathepsin L-like protease 0.0134 0.0337 0.0337
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0052 0.0111
Echinococcus granulosus glycine receptor subunit alpha 1 0.0058 0.0113 0.0281
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0004 0.0032
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0039 0.0098
Schistosoma mansoni hypothetical protein 0.021 0.056 0.1394
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0025 0.0015 0.0114
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0058 0.0113 0.0239
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.017 0.0424
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0035 0.0075
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0094 0.0094
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0026 0.0016 0.0054
Echinococcus granulosus laminin 0.0274 0.075 0.1869
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0031 0.0033 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.0616 0.176 0.8223
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0052 0.013
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Plasmodium falciparum ferrodoxin reductase-like protein 0.0037 0.0051 0.0304
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0116 0.0284 0.0707
Echinococcus granulosus glycine receptor subunit alpha 1 0.0058 0.0113 0.0281
Leishmania major cathepsin L-like protease 0.0035 0.0044 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0039 0.0098
Echinococcus multilocularis glycine receptor subunit beta 0.0058 0.0113 0.0239
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0037 0.0051 0.0108
Loa Loa (eye worm) hypothetical protein 0.0116 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Mycobacterium leprae Probable polyketide synthase Pks1 0.0027 0.0021 0.007
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0037 0.0051 0.017
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0026 0.0016 0.0054
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0044 0.0137
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.006 0.0149
Brugia malayi Aldehyde dehydrogenase protein 4 0.0025 0.0015 0.0015
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0059 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0035 0.0044 0.0137
Onchocerca volvulus 0.0032 0.0035 0.0109
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.065 0.1862 0.1862
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0059 0.0199
Toxoplasma gondii kringle domain-containing protein 0.0588 0.1677 0.4944
Echinococcus granulosus smad 0.0024 0.0011 0.0028
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0035 0.0035
Echinococcus granulosus notch 0.0157 0.0404 0.1006
Schistosoma mansoni egf-like domain protein 0.0274 0.075 0.1869
Loa Loa (eye worm) glutathione reductase 0.0407 0.1143 0.1143
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.006 0.0149
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0007 0.0025
Brugia malayi Heterochromatin protein 1 0.007 0.0148 0.0147
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0035 0.0035
Chlamydia trachomatis thioredoxin reductase 0.0037 0.0051 0.1426
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0065 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.015 0.015
Mycobacterium ulcerans hypothetical protein 0.004 0.0059 0.046
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0016 0.0054
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.021 0.056 0.1394
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0038 0.0051 0.0051
Brugia malayi glutamate synthase 0.0037 0.0051 0.0051
Schistosoma mansoni zinc finger protein 0.003 0.003 0.0075
Schistosoma mansoni neurotransmitter gated ion channel 0.0027 0.002 0.005
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0037 0.0051 0.0051
Echinococcus granulosus protein jagged 2 0.0157 0.0404 0.1006
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0099 0.0209
Echinococcus granulosus lamin dm0 0.0111 0.0269 0.0671
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.015 0.015
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.021 0.056 0.1394
Entamoeba histolytica hypothetical protein 0.0038 0.0052 0.0256
Schistosoma mansoni amine oxidase 0.002 0.0000037133 0.0000092482
Schistosoma mansoni neuropeptide receptor 0.0032 0.0035 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0004 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Brugia malayi Importin beta-1 subunit 0.0061 0.012 0.012
Brugia malayi Dopamine receptor protein 1 0.0032 0.0035 0.0035
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0054 0.0099 0.0099
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0004 0.0014
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0035 0.0088
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0004 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0506 0.1435 0.1435
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Onchocerca volvulus 0.0111 0.0269 0.0834
Entamoeba histolytica serine/threonine protein kinase, putative 0.0616 0.176 1
Trypanosoma cruzi trypanothione reductase, putative 0.0407 0.1143 0.1143
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0025 0.0015 0.0209
Brugia malayi steroid hormone receptor 0.0071 0.015 0.015
Onchocerca volvulus Serine\/threonine kinase homolog 0.0616 0.176 0.5447
Schistosoma mansoni rab6-interacting 0.0058 0.0112 0.0279
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0173 0.1034
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0173 0.0169
Onchocerca volvulus 0.0129 0.032 0.0992
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0035 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Schistosoma mansoni hypothetical protein 0.0032 0.0035 0.0088
Brugia malayi Cathepsin L-like precursor 0.0024 0.001 0.001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0037 0.0051 0.0192
Echinococcus granulosus protein jagged 1 0.0157 0.0404 0.1006
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0025 0.0015 0.0114
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0051 0.0128
Onchocerca volvulus 0.0111 0.0269 0.0834
Onchocerca volvulus 0.0058 0.0112 0.0347
Echinococcus granulosus thioredoxin glutathione reductase 0.0407 0.1143 0.2846
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0044 0.0044
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.012 0.0116
Onchocerca volvulus 0.0157 0.0404 0.125
Mycobacterium ulcerans beta-lactamase 0.004 0.0059 0.046
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0035 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0141 0.0357 0.0353
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.021 0.056 0.1394
Brugia malayi hypothetical protein 0.0033 0.0039 0.0039
Echinococcus granulosus mixed lineage leukemia protein mll 0.0035 0.0043 0.0106
Schistosoma mansoni biogenic amine receptor 0.0032 0.0035 0.0088
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0029 0.0226
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0052 0.013
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0035 0.0088
Echinococcus granulosus RUN 0.0058 0.0112 0.0279
Loa Loa (eye worm) hypothetical protein 0.0069 0.0143 0.0143
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0061 0.0119 0.0252
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0021 0.0001 0.0004
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0165 0.0164
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Echinococcus granulosus glycoprotein Antigen 5 0.06 0.1713 0.4265
Echinococcus granulosus histone lysine methyltransferase setb 0.0116 0.0284 0.0707
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0129 0.032 0.0317
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0086 0.0359
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0027 0.002 0.0042
Onchocerca volvulus 0.0032 0.0035 0.0109
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0025 0.0015 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0059 0.0233
Brugia malayi hypothetical protein 0.0027 0.002 0.002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0299 0.0823 0.0823
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0035 0.0088
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0035 0.0088
Echinococcus granulosus nAChR subunit 0.0031 0.0033 0.0083
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0928 0.2683 0.8976
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0035 0.0075
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0039 0.0122
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0058 0.0113 0.0113
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.0702 0.2347
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0035 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0051 0.0051
Leishmania major NADH dehydrogenase, putative 0.0037 0.0051 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Onchocerca volvulus Putative nachr subunit 0.0058 0.0113 0.035
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0037 0.0051 0.0394
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Onchocerca volvulus 0.0238 0.0645 0.1996
Echinococcus multilocularis expressed protein 0.0738 0.2121 0.448
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0035 0.0075
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0058 0.0227
Echinococcus multilocularis cysteine protease 0.0035 0.0044 0.0094
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0141 0.0357 0.0889
Loa Loa (eye worm) beta-lactamase 0.004 0.0059 0.0059
Plasmodium vivax ferrodoxin reductase, putative 0.0037 0.0051 0.0304
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.0051
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0037 0.0051 0.0051
Echinococcus multilocularis geminin 0.1379 0.4015 0.8481
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0058 0.0113 0.0113
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0031 0.0033 0.0033
Brugia malayi notch-like transmembrane receptor 0.0157 0.0404 0.0404
Echinococcus granulosus enteropeptidase 0.06 0.1713 0.4265
Schistosoma mansoni hypothetical protein 0.0247 0.0671 0.1672
Schistosoma mansoni lamin 0.0111 0.0269 0.0671
Mycobacterium ulcerans aldehyde dehydrogenase 0.0457 0.1292 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0037 0.0051 0.0127
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0004 0.0014
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0025 0.0015 0.0022
Leishmania major hypothetical protein, conserved 0.0588 0.1677 0.1677
Loa Loa (eye worm) hypothetical protein 0.004 0.0059 0.0059
Echinococcus multilocularis laminin 0.0274 0.075 0.1585
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0129 0.032 0.032
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.006 0.0149
Toxoplasma gondii histone lysine methyltransferase SET1 0.0244 0.0661 0.1948
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0165 0.041
Toxoplasma gondii hypothetical protein 0.004 0.006 0.0177
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0058 0.0113 0.0113
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0015 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0039 0.0098
Brugia malayi Calcium binding EGF domain containing protein 0.0157 0.0404 0.0404
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0004 0.0032
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0506 0.1435 0.1435
Leishmania major cathepsin L-like protease 0.0035 0.0044 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Schistosoma mansoni notch 0.0157 0.0404 0.1006
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0152 0.0378
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0044 0.0264
Schistosoma mansoni thyroid hormone receptor 0.0318 0.0881 0.2194
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0035 0.0088
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0025 0.0015 0.0031
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0037 0.0051 0.0394
Leishmania major trypanothione reductase 0.0407 0.1143 0.1143
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0165 0.0164
Onchocerca volvulus 0.0212 0.0567 0.1753
Brugia malayi glutathione reductase 0.0407 0.1143 0.1143
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.015 0.0317
Brugia malayi Bromodomain containing protein 0.0096 0.0224 0.0224
Echinococcus multilocularis smad 0.0024 0.0011 0.0024
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0337 0.0337
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0037 0.0051 0.0192
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0058 0.0113 0.0113
Echinococcus granulosus allatostatin A receptor 0.0032 0.0035 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Brugia malayi Cathepsin L-like precursor 0.0035 0.0044 0.0044
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0274 0.075 0.1869
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0058 0.0113 0.0113
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0173 0.0173
Leishmania major hypothetical protein, conserved 0.0037 0.0051 0.0051
Brugia malayi EGF-like domain containing protein 0.0157 0.0404 0.0404
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.015 0.0374
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Echinococcus granulosus FTZ F1 alpha 0.0071 0.015 0.0374
Brugia malayi Trypsin family protein 0.021 0.056 0.056
Echinococcus multilocularis fat cadherin tumor suppressor 0.0157 0.0404 0.0853
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0065 0.026
Giardia lamblia NADH oxidase lateral transfer candidate 0.0141 0.0357 0.1961
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0496 0.1407 0.3503
Onchocerca volvulus Slit protein homolog 0.0157 0.0404 0.125
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0025 0.0015 0.0011
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Brugia malayi MH2 domain containing protein 0.0353 0.0983 0.0983
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0141 0.0357 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.015 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0067
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0052 0.013
Schistosoma mansoni hypothetical protein 0.0035 0.0045 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Onchocerca volvulus 0.0058 0.0113 0.035
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0045 0.0095
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.015 0.0374
Onchocerca volvulus 0.0027 0.002 0.0062
Echinococcus granulosus Mastin 0.06 0.1713 0.4265
Onchocerca volvulus 0.021 0.056 0.1732
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Trichomonas vaginalis chromobox protein, putative 0.007 0.0148 0.0646
Brugia malayi hypothetical protein 0.0079 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Onchocerca volvulus 0.0058 0.0113 0.035
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0031 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0071 0.015 0.015
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0052 0.0052
Brugia malayi neuropeptide F receptor 0.0032 0.0035 0.0035
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0015 0.0037
Toxoplasma gondii melibiase subfamily protein 0.0103 0.0245 0.0722
Schistosoma mansoni myosin xvIII 0.0032 0.0035 0.0088
Echinococcus granulosus neurogenic locus protein delta 0.0157 0.0404 0.1006
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0496 0.1407 0.8389
Mycobacterium tuberculosis Conserved protein 0.004 0.0059 0.0199
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0112 0.0237
Brugia malayi Cathepsin L-like precursor 0.0035 0.0044 0.0044
Brugia malayi Delta serrate ligand family protein 0.0157 0.0404 0.0404
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0073 0.0215
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0035 0.0075
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0044 0.0211
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.015 0.0465
Brugia malayi chromobox protein homolog 3 0.0039 0.0056 0.0056
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0141 0.0357 0.1053
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.015 0.015
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0037 0.0051 0.0127
Entamoeba histolytica hypothetical protein 0.0049 0.0086 0.045
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0116 0.0389
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0141 0.0357 0.0353
Echinococcus multilocularis protoporphyrinogen oxidase 0.002 0.0000037133 0.0000078435
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) Smad1 0.0024 0.0011 0.0011
Leishmania major cytochrome p450-like protein 0.0022 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0033
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0152 0.032
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1622 0.4734 1
Echinococcus multilocularis tumor protein p63 0.0328 0.091 0.1921
Brugia malayi nuclear hormone receptor 0.0033 0.0039 0.0039
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0025 0.0015 0.0015
Brugia malayi Cathepsin L-like precursor 0.0035 0.0044 0.0044
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0035 0.0035
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0038 0.0051 0.0128
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0035 0.0035
Schistosoma mansoni lipoxygenase 0.0287 0.0788 0.1962
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0038 0.0051 0.0047
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.0656 0.1634
Plasmodium vivax multidomain scavenger receptor, putative 0.0058 0.0112 0.0668
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0496 0.1407 0.3503
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0052 0.0052
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0021 0.0001 0.001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0287 0.0788 0.1962
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0052 0.0052
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0058 0.0113 0.0281
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0004 0.0032
Echinococcus granulosus lamin 0.0111 0.0269 0.0671
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0035 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Onchocerca volvulus 0.0032 0.0035 0.0109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0058 0.0227
Leishmania major cytochrome p450-like protein 0.0022 0.0004 0.0004
Schistosoma mansoni acetylcholine receptor-related 0.0027 0.002 0.005
Mycobacterium ulcerans polyketide synthase 0.0026 0.0016 0.0125
Loa Loa (eye worm) hypothetical protein 0.0058 0.0112 0.0112
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0039 0.0039
Brugia malayi excitatory GABA receptor EXP-1A 0.0058 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.065 0.1862 0.4639
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0044 0.0162
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0027 0.0021 0.007
Schistosoma mansoni amine GPCR 0.0032 0.0035 0.0088
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0035 0.0088
Mycobacterium tuberculosis Probable dehydrogenase 0.0928 0.2683 0.8976
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0058 0.0227
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0039
Brugia malayi hypothetical protein 0.0032 0.0035 0.0035
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0004 0.0014
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0457 0.1292 0.3218
Loa Loa (eye worm) hypothetical protein 0.0212 0.0567 0.0566
Leishmania major cathepsin L-like protease 0.0035 0.0044 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0058 0.0227
Schistosoma mansoni cercarial elastase (S01 family) 0.021 0.056 0.1394
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0141 0.0357 0.0357
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0037 0.0051 0.0127
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0035 0.0075
Schistosoma mansoni biogenic amine receptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0048 0.0082 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0108 0.0258 0.0643
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0035 0.0088
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.015 0.0374
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.015 0.0374
Brugia malayi PXA domain containing protein 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0247 0.0671 0.1418
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0129 0.032 0.0677
Loa Loa (eye worm) hypothetical protein 0.0079 0.0173 0.0173
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0116 0.0246
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0056 0.0175
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Schistosoma mansoni serine/threonine protein kinase 0.0616 0.176 0.4384
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0052 0.013
Schistosoma mansoni hypothetical protein 0.0058 0.0112 0.0279
Loa Loa (eye worm) hypothetical protein 0.0084 0.0188 0.0188
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0004 0.0032
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0015 0.0015
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.006 0.0149
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0035 0.0088
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0173 0.0173
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0037 0.0051 0.0108
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0025 0.0015 0.0114
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0059 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Brugia malayi ecdysteroid receptor 0.0071 0.015 0.015
Loa Loa (eye worm) latrophilin receptor protein 2 0.0094 0.022 0.022
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0025 0.0015 0.0049
Toxoplasma gondii PAN domain-containing protein 0.0212 0.0567 0.167
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Mycobacterium tuberculosis Probable oxidoreductase 0.1032 0.2989 1
Echinococcus multilocularis 0.002 0.0000037133 0.0000078435
Brugia malayi hypothetical protein 0.004 0.006 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0051 0.0051
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0037 0.0051 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0035 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0023 0.0059
Echinococcus granulosus tumor protein p63 0.0328 0.091 0.2265
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0033 0.0083
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0206 0.0513
Loa Loa (eye worm) hypothetical protein 0.0502 0.1424 0.1424
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0025 0.0015 0.0114
Loa Loa (eye worm) hypothetical protein 0.0157 0.0404 0.0404
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0052 0.0111
Toxoplasma gondii microneme protein MIC17B 0.0212 0.0567 0.167
Trypanosoma cruzi NADH dehydrogenase, putative 0.0037 0.0051 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0004 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0506 0.1435 0.1435
Schistosoma mansoni hypothetical protein 0.0157 0.0404 0.1006
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0141 0.0357 0.0353
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0025 0.0015 0.0011
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0058 0.0058
Onchocerca volvulus 0.0031 0.0033 0.0103
Brugia malayi sulfakinin receptor protein 0.0032 0.0035 0.0035
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0066 0.0164
Brugia malayi PAN domain containing protein 0.0212 0.0567 0.0566
Echinococcus granulosus glycine receptor subunit beta 0.0058 0.0113 0.0281
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0065 0.0202
Trypanosoma brucei trypanothione reductase 0.0407 0.1143 0.1139
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0287 0.0788 0.6099
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0058 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0032 0.0035 0.0088
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.007 0.0148
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0035 0.0088
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.015 0.015
Entamoeba histolytica disulphide oxidoreductase, putative 0.0037 0.0051 0.0248
Onchocerca volvulus 0.0058 0.0113 0.035
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0035 0.0075
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0179 0.0445
Brugia malayi Cathepsin L-like precursor 0.0035 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.004 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0129 0.032 0.0677
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0037 0.0051 0.015
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0058 0.0113 0.0113
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0004
Brugia malayi conserved hypotetical protein 0.0033 0.0039 0.0039
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0179 0.0378
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0000037133 0.0000092482
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.004 0.01
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0058 0.0113 0.0281
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0025 0.0015 0.0015
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0052 0.013
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0247 0.0671 0.1672
Onchocerca volvulus 0.004 0.006 0.0185
Schistosoma mansoni sodium/chloride dependent transporter 0.0238 0.0645 0.1606
Treponema pallidum sodium- and chloride- dependent transporter 0.0238 0.0645 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0165 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0305 0.0841 0.3905
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.015 0.015
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0007 0.0022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0094 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0337 0.0333
Schistosoma mansoni notch 0.0157 0.0404 0.1006
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0015 0.0037
Schistosoma mansoni nAChR subunit 0.0058 0.0113 0.0281
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0035 0.0075
Echinococcus granulosus glutamate NMDA receptor subunit 0.0061 0.0119 0.0297
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0113
Echinococcus multilocularis serotonin receptor 0.0165 0.0427 0.0903
Schistosoma mansoni biogenic amine (5HT) receptor 0.0165 0.0427 0.1064
Loa Loa (eye worm) PAN domain-containing protein 0.0212 0.0567 0.0566
Brugia malayi tailless protein 0.0033 0.0039 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0141 0.0357 0.0357
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0035 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0044 0.0162
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.002
Trichomonas vaginalis esterase, putative 0.004 0.0059 0.0233
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0037 0.0051 0.0127
Onchocerca volvulus 0.0212 0.0567 0.1753
Schistosoma mansoni hypothetical protein 0.0204 0.0544 0.1354
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0051 0.0128
Schistosoma mansoni adenoreceptor 0.0032 0.0035 0.0088
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0058 0.0058
Onchocerca volvulus 0.0081 0.0179 0.0553
Brugia malayi GnHR receptor homolog 0.0032 0.0035 0.0035
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0044 0.0137
Leishmania major C-8 sterol isomerase-like protein 0.3404 1 1
Leishmania major hypothetical protein, conserved 0.0037 0.0051 0.0051
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0037 0.0051 0.0394
Schistosoma mansoni nuclear hormone receptor 0.0071 0.015 0.0374
Echinococcus multilocularis 0.0022 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0274 0.075 0.075
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0025 0.0014 0.0046
Echinococcus multilocularis muscleblind protein 1 0.0307 0.0847 0.179
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0122 0.0302 0.0302

Activities

Activity type Activity value Assay description Source Reference
Complex formation (binding) = 140 % Percentage of intracellular covalent DNA-topoisomerase II complexes formed ChEMBL. 12014968
Protein-DNA complex formation (functional) = 140 % Compound tested for ability to form a cellular covalent topoisomerase II-DNA complex. ChEMBL. 8691468

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.