Detailed information for compound 1104889

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 515.557 | Formula: C29H29N3O6
  • H donors: 2 H acceptors: 5 LogP: 3.44 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N[C@]12CCC(=O)[C@H]3[C@]42CCN([C@@H]1Cc1c4c(O3)c(cc1)O)CC1CC1)/C=C/c1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C29H29N3O6/c33-21-9-6-19-15-23-29(30-24(35)10-5-17-3-7-20(8-4-17)32(36)37)12-11-22(34)27-28(29,25(19)26(21)38-27)13-14-31(23)16-18-1-2-18/h3-10,18,23,27,33H,1-2,11-16H2,(H,30,35)/b10-5+/t23-,27+,28+,29-/m1/s1
  • InChiKey: USUATCCCIDHRPH-DNIKMYEQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens opioid receptor, kappa 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, delta 1 Starlite/ChEMBL References
Bos taurus Mu opioid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni neuropeptide F-like receptor Mu opioid receptor   401 aa 335 aa 20.9 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Mu opioid receptor   401 aa 373 aa 27.3 %
Echinococcus multilocularis allatostatin A receptor Mu opioid receptor   401 aa 341 aa 29.0 %
Onchocerca volvulus Mu opioid receptor   401 aa 321 aa 20.9 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Mu opioid receptor   401 aa 334 aa 23.4 %
Onchocerca volvulus Programmed cell death protein 5 homolog Mu opioid receptor   401 aa 323 aa 24.1 %
Onchocerca volvulus Mu opioid receptor   401 aa 354 aa 24.6 %
Echinococcus granulosus allatostatin A receptor Mu opioid receptor   401 aa 346 aa 29.2 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Mu opioid receptor   401 aa 385 aa 23.4 %
Echinococcus granulosus thyrotropin releasing hormone receptor Mu opioid receptor   401 aa 373 aa 27.6 %
Onchocerca volvulus Mu opioid receptor   401 aa 341 aa 26.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans hypothetical protein 0.0042 0.0017 0.0025
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0058 0.0034 0.0068
Loa Loa (eye worm) MBOAT family protein 0.0248 0.0241 0.0544
Schistosoma mansoni ap endonuclease 0.0076 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0462 0.0472 0.1067
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0059 0.0035 0.0035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.007 0.0047 0.0434
Loa Loa (eye worm) hypothetical protein 0.011 0.0091 0.0205
Brugia malayi ORL1-like opioid receptor 0.084 0.0883 0.337
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0028 0.0028
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.012 0.0101 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0083
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0047 0.0107
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0015 0.0048
Plasmodium falciparum phosphodiesterase gamma, putative 0.0059 0.0035 0.2286
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0076 0.0054 0.02
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0058 0.0034 0.0068
Echinococcus multilocularis carbonyl reductase 1 0.0048 0.0024 0.0024
Loa Loa (eye worm) glutaminase 0.0559 0.0578 0.1306
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Loa Loa (eye worm) STAT protein 0.0137 0.012 0.0271
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0048 0.0024 0.0024
Echinococcus granulosus peptide allatostatin:somatostatin 0.084 0.0883 0.0883
Trypanosoma brucei short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Toxoplasma gondii hypothetical protein 0.0044 0.0018 0.0158
Echinococcus multilocularis histone deacetylase 6 0.0038 0.0012 0.0012
Trypanosoma cruzi DNA topoisomerase II, putative 0.0136 0.0118 0.0445
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.084 0.0883 0.1994
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0136 0.0118 0.0293
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.0028 0.0098
Onchocerca volvulus 0.084 0.0883 0.3631
Schistosoma mansoni histone deacetylase hda2 0.0038 0.0012 0.0012
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.0099 0.0099
Onchocerca volvulus 0.084 0.0883 0.3631
Echinococcus granulosus geminin 0.0347 0.0347 0.0347
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0079 0.0079
Onchocerca volvulus 0.0048 0.0024 0.0081
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0003 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.0028 0.0106
Echinococcus granulosus histone deacetylase 3 0.004 0.0014 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0017 0.0125
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.0208
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0048 0.0024 0.0083
Loa Loa (eye worm) hypothetical protein 0.0085 0.0064 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0008 0.0217
Plasmodium vivax SET domain protein, putative 0.0287 0.0283 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0431 0.0439 0.0439
Loa Loa (eye worm) histone deacetylase 7A 0.0038 0.0012 0.0027
Echinococcus granulosus tar DNA binding protein 0.0066 0.0043 0.0043
Schistosoma mansoni biogenic amine receptor 0.084 0.0883 0.0883
Onchocerca volvulus 0.0044 0.0018 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.0323 0.1334
Leishmania major mitochondrial DNA topoisomerase II 0.0136 0.0118 0.0445
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.009 0.0217
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0048 0.0024 0.0083
Onchocerca volvulus 0.084 0.0883 0.3631
Brugia malayi STAT protein, DNA binding domain containing protein 0.0137 0.012 0.0458
Loa Loa (eye worm) hypothetical protein 0.0583 0.0604 0.1365
Mycobacterium ulcerans lipase LipD 0.0109 0.009 0.0217
Echinococcus multilocularis muscleblind protein 0.061 0.0634 0.0634
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0626 0.0651 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.0158
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0326 0.0325 0.0843
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0018 0.0018
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0136 0.0118 0.0445
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.0028 0.0063
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Schistosoma mansoni cpg binding protein 0.0119 0.0101 0.0101
Schistosoma mansoni endoplasmin 0.0136 0.0118 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0155 0.0139 0.0524
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0097 0.0077 0.0316
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0015 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.0028 0.0063
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0256 0.025 0.025
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0022 0.0022
Brugia malayi hypothetical protein 0.0462 0.0472 0.1804
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.084 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.0098 0.0078 0.0176
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0274 0.0268 0.0268
Brugia malayi Retinol dehydrogenase 12 0.0048 0.0024 0.009
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0383 0.0387 0.1472
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0306 0.0303 0.0784
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0136 0.0118 0.0473
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0001 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0058 0.0034 0.0068
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0431 0.0439 0.0439
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Brugia malayi sulfakinin receptor protein 0.084 0.0883 0.337
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0325 0.0324 0.0324
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0072 0.0164
Brugia malayi beta-lactamase family protein 0.0109 0.009 0.0343
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.0028 0.0098
Brugia malayi hypothetical protein 0.0695 0.0725 0.277
Entamoeba histolytica hypothetical protein 0.0145 0.0129 0.0923
Brugia malayi glutaminase DH11.1 0.0559 0.0578 0.2207
Schistosoma mansoni amine GPCR 0.084 0.0883 0.0883
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0051 0.0212
Onchocerca volvulus 0.084 0.0883 0.3631
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Loa Loa (eye worm) RecQ helicase 0.0044 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0256 0.025 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0035 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Onchocerca volvulus 0.2259 0.2423 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0626 0.0651 0.1707
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0136 0.0118 0.0293
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0048 0.0024 0.0149
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0048 0.0024 0.0041
Treponema pallidum exodeoxyribonuclease (exoA) 0.0076 0.0054 0.0373
Leishmania major hypothetical protein, conserved 0.0059 0.0035 0.0126
Toxoplasma gondii histone deacetylase HDAC3 0.004 0.0014 0.0117
Trypanosoma brucei short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0294 0.029 0.029
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Brugia malayi Thioredoxin reductase 0.0098 0.0077 0.0296
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.0028 0.0028
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.009 0.0217
Schistosoma mansoni pyruvate dehydrogenase 0.2439 0.2619 0.2619
Plasmodium vivax histone deacetylase 1, putative 0.004 0.0014 0.0433
Echinococcus multilocularis g protein coupled receptor 0.084 0.0883 0.0883
Brugia malayi RNA, U transporter 1 0.0085 0.0063 0.0241
Mycobacterium ulcerans dehydrogenase 0.0048 0.0024 0.0041
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0111 0.0092 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Giardia lamblia hypothetical protein 0.0059 0.0035 0.0232
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0008 0.0018
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0003 0.0014
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) hypothetical protein 0.1305 0.1388 0.3135
Mycobacterium tuberculosis Probable oxidoreductase 0.0048 0.0024 0.0041
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0058 0.0034 0.0121
Entamoeba histolytica hypothetical protein 0.0145 0.0129 0.0923
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0136 0.0118 1
Brugia malayi Cytochrome P450 family protein 0.0093 0.0072 0.0276
Brugia malayi hypothetical protein 0.0028 0.0001 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Onchocerca volvulus 0.0048 0.0024 0.0081
Leishmania major histone deacetylase, putative 0.0038 0.0012 0.0038
Leishmania major dehydrogenase-like protein 0.0048 0.0024 0.0083
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) norepinephrine transporter 0.0256 0.025 0.0564
Trypanosoma brucei heat shock protein 90, putative 0.0136 0.0118 0.0445
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0058 0.0034 0.0068
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Schistosoma mansoni carbonyl reductase 0.0048 0.0024 0.0024
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.006 0.0246
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0136 0.0118 0.1702
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0059 0.0035 0.0144
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Giardia lamblia Kinase, CMGC MAPK 0.0154 0.0138 0.099
Plasmodium vivax histone acetyltransferase GCN5, putative 0.009 0.0069 0.2388
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.009 0.0343
Schistosoma mansoni thyroid hormone receptor 0.0052 0.0028 0.0028
Loa Loa (eye worm) dehydrogenase 0.0048 0.0024 0.0053
Brugia malayi latrophilin 2 splice variant baaae 0.0215 0.0205 0.0781
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.0028 0.0028
Toxoplasma gondii cytochrome p450 superfamily protein 0.0058 0.0034 0.0304
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni 6-phosphofructokinase 0.011 0.009 0.009
Brugia malayi Inositol-1 0.0039 0.0014 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0016 0.0066
Onchocerca volvulus 0.084 0.0883 0.3631
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.084 0.0883 0.337
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.0208
Echinococcus multilocularis neuropeptides capa receptor 0.084 0.0883 0.0883
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0028 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0083
Echinococcus granulosus neuropeptide FF receptor 2 0.084 0.0883 0.0883
Brugia malayi Serotonin receptor 0.084 0.0883 0.337
Schistosoma mansoni neuropeptide receptor 0.084 0.0883 0.0883
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.009 0.0204
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0018 0.0018
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.009 0.0217
Giardia lamblia Hypothetical protein 0.0059 0.0035 0.0232
Echinococcus multilocularis geminin 0.0347 0.0347 0.0347
Echinococcus granulosus mitogen activated protein kinase 11 0.025 0.0243 0.0243
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0422 0.0429 0.1769
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0315 0.0313 0.0706
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.006 0.0414
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0003 0.0008
Trypanosoma cruzi Heat shock protein 83, putative 0.0136 0.0118 0.0445
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0058 0.0034 0.0068
Echinococcus granulosus G protein coupled receptor 139 0.084 0.0883 0.0883
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0098 0.0078 0.0078
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0224 0.0214 0.0546
Echinococcus multilocularis expressed protein 0.0364 0.0366 0.0366
Loa Loa (eye worm) hypothetical protein 0.2083 0.2233 0.5044
Echinococcus granulosus potassium voltage gated channel subfamily H 0.012 0.0101 0.0101
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0224 0.0214 0.0546
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.2286
Plasmodium falciparum histone deacetylase 2 0.0038 0.0012 0.069
Echinococcus multilocularis neuropeptide s receptor 0.2264 0.2429 0.2429
Echinococcus multilocularis histone deacetylase 1 0.004 0.0014 0.0014
Brugia malayi putative neuropeptide receptor 0.084 0.0883 0.337
Loa Loa (eye worm) G-protein coupled receptor 0.084 0.0883 0.1994
Schistosoma mansoni jumonji/arid domain-containing protein 0.0052 0.0028 0.0028
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0003 0.0006
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Schistosoma mansoni peptide (allatostatin)-like receptor 0.084 0.0883 0.0883
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0059 0.0035 0.0126
Echinococcus granulosus 7tm_1 domain containing protein 0.084 0.0883 0.0883
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0008 0.0322
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0136 0.0118 0.0293
Schistosoma mansoni jumonji domain containing protein 0.0088 0.0067 0.0067
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0058 0.0034 0.0068
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0318 0.0316 0.0715
Echinococcus multilocularis chromobox protein 1 0.0074 0.0051 0.0051
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.009 0.0219
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0018 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0048 0.0024 0.0053
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0058 0.0034 0.0068
Schistosoma mansoni bromodomain containing protein 0.0157 0.0141 0.0141
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.009 0.0371
Trypanosoma cruzi short chain dehydrogenase, putative 0.0048 0.0024 0.0083
Brugia malayi intermediate filament protein 0.0085 0.0063 0.0242
Loa Loa (eye worm) transcription factor SMAD2 0.037 0.0373 0.0842
Brugia malayi Receptor family ligand binding region containing protein 0.0031 0.0004 0.0016
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0048 0.0024 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0043 0.0043
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0004 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.0028 0.0106
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Echinococcus granulosus tm gpcr rhodopsin 0.2378 0.2552 0.2552
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.0012 0.0012
Echinococcus granulosus retinol dehydrogenase 11 0.0048 0.0024 0.0024
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0136 0.0118 0.0293
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0093 0.0072 0.0171
Brugia malayi cytochrome P450 0.0058 0.0034 0.0128
Trypanosoma cruzi heat shock protein 85, putative 0.0136 0.0118 0.0445
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0907 0.0955 0.0955
Echinococcus granulosus microtubule associated protein 2 0.136 0.1447 0.1447
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Plasmodium falciparum histone acetyltransferase GCN5 0.0078 0.0055 0.3709
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.01 0.0079 0.0179
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0076 0.0054 0.0373
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0008 0.0008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0224 0.0214 0.3189
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0003 0.0014
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.0004 0.0008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0003 0.0103
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0306 0.0303 0.0303
Plasmodium falciparum histone deacetylase, putative 0.0038 0.0012 0.069
Echinococcus multilocularis mitogen activated protein kinase 11 0.025 0.0243 0.0243
Schistosoma mansoni heat shock protein 0.0136 0.0118 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Schistosoma mansoni 6-phosphofructokinase 0.011 0.009 0.009
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0048 0.0024 0.0083
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Echinococcus granulosus somatostatin receptor 0.084 0.0883 0.0883
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Echinococcus granulosus chromobox protein 1 0.0074 0.0051 0.0051
Onchocerca volvulus Neuropeptide F receptor homolog 0.084 0.0883 0.3631
Schistosoma mansoni hypothetical protein 0.01 0.0079 0.0079
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0014 0.0056
Schistosoma mansoni hypothetical protein 0.01 0.0079 0.0079
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0098 0.0078 0.0078
Echinococcus multilocularis survival motor neuron protein 1 0.0695 0.0725 0.0725
Toxoplasma gondii endonuclease IV APN 0.0161 0.0146 0.1387
Mycobacterium tuberculosis Possible oxidoreductase 0.0048 0.0024 0.0041
Trichomonas vaginalis helicase, putative 0.0027 0 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.084 0.0883 0.0883
Brugia malayi AKH receptor 0.084 0.0883 0.337
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0031 0.0004 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.0028 0.0063
Schistosoma mansoni amine GPCR 0.084 0.0883 0.0883
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Onchocerca volvulus 0.0048 0.0024 0.0081
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0058 0.0034 0.0121
Mycobacterium ulcerans carveol-like dehydrogenase 0.0048 0.0024 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0043 0.0043
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Loa Loa (eye worm) hypothetical protein 0.0147 0.013 0.0294
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Loa Loa (eye worm) hypothetical protein 0.0136 0.0118 0.0267
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0048 0.0024 0.0083
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0383 0.0387 0.1472
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.0028 0.0028
Echinococcus multilocularis alpha 1A adrenergic receptor 0.084 0.0883 0.0883
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0058 0.0034 0.0121
Echinococcus granulosus metabotropic glutamate receptor 2 0.01 0.0079 0.0079
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0422 0.0429 0.1769
Entamoeba histolytica short chain dehydrogenase family protein 0.0048 0.0024 0.0149
Brugia malayi Serotonin receptor 0.1786 0.191 0.7293
Trypanosoma brucei glucosidase, putative 0.0082 0.006 0.0221
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Mycobacterium tuberculosis Possible two component sensor kinase 0.0136 0.0118 0.0293
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0058 0.0034 0.0068
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0256 0.025 0.0953
Schistosoma mansoni chromobox protein 0.0074 0.0051 0.0051
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.084 0.0883 0.0883
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0058 0.0034 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.0028 0.0106
Trichomonas vaginalis set domain proteins, putative 0.2259 0.2423 1
Leishmania major histone deacetylase, putative 0.004 0.0014 0.0046
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.084 0.0883 0.0883
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0058 0.0034 0.0068
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0422 0.0429 0.1769
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi hypothetical protein 0.0085 0.0064 0.0243
Brugia malayi larval opioid receptor 0.084 0.0883 0.337
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.0028 0.0028
Schistosoma mansoni alpha-glucosidase 0.0316 0.0314 0.0314
Loa Loa (eye worm) RNA binding protein 0.0066 0.0043 0.0097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0225
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.0028 0.0106
Echinococcus granulosus tm gpcr rhodopsin 0.084 0.0883 0.0883
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0058 0.0034 0.0068
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0059 0.0035 0.2286
Echinococcus multilocularis mitogen activated protein kinase 14 0.025 0.0243 0.0243
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0136 0.0118 0.0489
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0021 0.0046
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0058 0.0034 0.0068
Onchocerca volvulus 0.084 0.0883 0.3631
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.0028 0.0106
Leishmania major short chain dehydrogenase, putative 0.0048 0.0024 0.0083
Brugia malayi exodeoxyribonuclease III family protein 0.0076 0.0054 0.0207
Onchocerca volvulus 0.0294 0.029 0.1182
Schistosoma mansoni opsin-like receptor 0.084 0.0883 0.0883
Trypanosoma cruzi ISWI complex protein 0.0034 0.0009 0.0026
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0008 0.0023
Echinococcus multilocularis zinc finger protein 0.0058 0.0034 0.0034
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0048 0.0024 0.0024
Echinococcus multilocularis neuropeptide receptor 0.924 1 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1282 0.1362 1
Loa Loa (eye worm) beta-lactamase 0.0109 0.009 0.0203
Echinococcus multilocularis importin subunit beta 1 0.003 0.0003 0.0003
Toxoplasma gondii heat shock protein HSP90 0.0136 0.0118 0.1118
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0015 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.025 0.0243 0.092
Mycobacterium ulcerans glutaminase 0.0559 0.0578 0.1513
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0028 0.0028
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0626 0.0651 0.1707
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0058 0.0034 0.0068
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0035 0.0144
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Schistosoma mansoni histone deacetylase 4 5 0.0038 0.0012 0.0012
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0224 0.0214 0.0546
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0058 0.0034 0.0068
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0048 0.0024 0.0024
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0001 0.0003
Brugia malayi TAR-binding protein 0.0066 0.0043 0.0164
Loa Loa (eye worm) hypothetical protein 0.0315 0.0313 0.0706
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0083
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0018 0.0018
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0008 0.0217
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0014 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0031 0.0004 0.001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0009 0.0003
Echinococcus multilocularis sex peptide receptor 0.084 0.0883 0.0883
Echinococcus granulosus neuropeptide Y receptor 0.084 0.0883 0.0883
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.009 0.0371
Trypanosoma brucei histone deacetylase 1 0.004 0.0014 0.0046
Brugia malayi Bromodomain containing protein 0.0046 0.0021 0.0082
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0083
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0048 0.0024 0.0083
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0015 0.0015
Schistosoma mansoni amine GPCR 0.084 0.0883 0.0883
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.0028 0.0028
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1526 0.1628 0.6213
Brugia malayi Endoplasmin precursor 0.0136 0.0118 0.0452
Leishmania major cytochrome p450-like protein 0.0058 0.0034 0.0121
Loa Loa (eye worm) hypothetical protein 0.0695 0.0725 0.1639
Schistosoma mansoni growth hormone secretagogue receptor 0.084 0.0883 0.0883
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.012 0.0101 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.009 0.0336
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.0028 0.0028
Echinococcus multilocularis fmrfamide receptor 0.084 0.0883 0.0883
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.084 0.0883 0.337
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0161 0.0146 0.5147
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.009 0.0339
Brugia malayi Tachykinin-like peptides receptor 99D 0.084 0.0883 0.337
Brugia malayi putative neuropeptide receptor NPR1 0.084 0.0883 0.337
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.084 0.0883 0.1994
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0431 0.0439 0.0439
Echinococcus multilocularis mitogen activated protein kinase 3 0.0154 0.0138 0.0138
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0048 0.0024 0.0208
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0136 0.0118 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0018 0.1142
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.007
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.2439 0.2619 0.2619
Loa Loa (eye worm) hypothetical protein 0.061 0.0634 0.1432
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Trichomonas vaginalis heat shock protein, putative 0.0136 0.0118 0.0489
Mycobacterium ulcerans putative regulatory protein 0.0152 0.0136 0.0341
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0012 0.0012
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0136 0.0118 0.0293
Schistosoma mansoni biogenic amine (dopamine) receptor 0.084 0.0883 0.0883
Schistosoma mansoni transcription factor LCR-F1 0.0145 0.0129 0.0129
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0028 0.0063
Echinococcus granulosus dnaJ subfamily B 0.1277 0.1357 0.1357
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.0126
Toxoplasma gondii oxidoreductase, putative 0.0048 0.0024 0.0208
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.2083 0.2233 0.2233
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.009 0.0336
Loa Loa (eye worm) neuropeptide F receptor 0.084 0.0883 0.1994
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0014 0.0045
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0048 0.0024 0.0083
Leishmania major developmentally regulated phosphoprotein-like protein 0.2439 0.2619 1
Loa Loa (eye worm) thioredoxin reductase 0.0098 0.0077 0.0175
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0048 0.0024 0.0024
Brugia malayi Histone deacetylase family protein 0.0038 0.0012 0.0045
Schistosoma mansoni methyl-cpg binding protein mbd 0.0038 0.0013 0.0013
Onchocerca volvulus 0.0299 0.0296 0.1206
Giardia lamblia Heat shock protein HSP 90-alpha 0.0136 0.0118 0.0846
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0038 0.0013 0.0013
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0059 0.0035 0.0133
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0048 0.0024 0.0097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.0028 0.0028
Loa Loa (eye worm) follicle stimulating hormone receptor 0.2081 0.223 0.5037
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Trypanosoma brucei DNA topoisomerase ii 0.0136 0.0118 0.0445
Mycobacterium tuberculosis Probable oxidoreductase 0.0048 0.0024 0.0041
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0383 0.0387 0.0387
Trypanosoma brucei short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Brugia malayi Ets-domain containing protein 0.0072 0.005 0.0189
Loa Loa (eye worm) bromodomain containing protein 0.0047 0.0022 0.005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0148 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0059 0.0035 0.0079
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0098 0.0078 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0012 0.0012
Echinococcus granulosus oxidoreductase 0.0048 0.0024 0.0024
Leishmania major short chain dehydrogenase/reductase, putative 0.0048 0.0024 0.0083
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0136 0.0118 0.8043
Mycobacterium tuberculosis Conserved protein 0.0109 0.009 0.0217
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0047 0.0023 0.0023
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.084 0.0883 0.0883
Brugia malayi G-protein coupled receptor 0.084 0.0883 0.337
Loa Loa (eye worm) hypothetical protein 0.0109 0.009 0.0203
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0004 0.0017
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.084 0.0883 0.0883
Schistosoma mansoni zinc finger protein 0.0034 0.0009 0.0009
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0012 0.0012
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Echinococcus granulosus carbonyl reductase 1 0.0048 0.0024 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Echinococcus granulosus tm gpcr rhodopsin 0.1718 0.1836 0.1836
Schistosoma mansoni thyroid hormone receptor 0.0052 0.0028 0.0028
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0142 0.0125 0.0477
Trypanosoma brucei cytochrome P450, putative 0.0093 0.0072 0.0269
Schistosoma mansoni hypothetical protein 0.084 0.0883 0.0883
Brugia malayi 6-phosphofructokinase 0.011 0.009 0.0346
Echinococcus granulosus lysine specific demethylase 5A 0.0052 0.0028 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Entamoeba histolytica heat shock protein 90, putative 0.0136 0.0118 0.0846
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Brugia malayi oxidoreductase 0.0048 0.0024 0.009
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0098 0.0078 0.0176
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) glutamate receptor 0.0119 0.01 0.0227
Schistosoma mansoni adenoreceptor 0.084 0.0883 0.0883
Plasmodium falciparum importin beta, putative 0.003 0.0003 0.0109
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0018 0.0076
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.084 0.0883 0.0883
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0048 0.0024 0.0083
Echinococcus multilocularis histone deacetylase 0.0038 0.0012 0.0012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0035 0.0144
Onchocerca volvulus 0.084 0.0883 0.3631
Trypanosoma cruzi DNA topoisomerase II, putative 0.0136 0.0118 0.0445
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0048 0.0024 0.0083
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Echinococcus multilocularis retinol dehydrogenase 11 0.0048 0.0024 0.0024
Schistosoma mansoni zinc finger protein 0.0248 0.0241 0.0241
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0048 0.0024 0.0081
Brugia malayi Latrophilin receptor protein 2 0.01 0.0079 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Onchocerca volvulus 0.0085 0.0063 0.0245
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Schistosoma mansoni amine GPCR 0.084 0.0883 0.0883
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.1176
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0008 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0045 0.002 0.008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Loa Loa (eye worm) hypothetical protein 0.4105 0.4426 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0211 0.02 0.0826
Plasmodium vivax hypothetical protein, conserved 0.0152 0.0136 0.4792
Schistosoma mansoni hypothetical protein 0.1277 0.1357 0.1357
Brugia malayi Dehydrogenases, short chain protein 30 0.0048 0.0024 0.009
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0079 0.0179
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0048 0.0024 0.0149
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0003 0.0014
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0326 0.0325 0.0843
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0136 0.0118 0.0489
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0001 0.0001
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Schistosoma mansoni neuropeptide f receptor 76f 0.084 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Plasmodium vivax hypothetical protein, conserved 0.0109 0.009 0.3131
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0035 0.0126
Loa Loa (eye worm) PDE1B protein 0.0059 0.0035 0.0079
Onchocerca volvulus 0.0048 0.0024 0.0081
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Loa Loa (eye worm) PHD-finger family protein 0.0047 0.0022 0.0049
Schistosoma mansoni biogenic amine (dopamine) receptor 0.084 0.0883 0.0883
Leishmania major alpha glucosidase II subunit, putative 0.0082 0.006 0.0221
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.009 0.0219
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.084 0.0883 0.1994
Mycobacterium ulcerans ketoacyl reductase 0.0048 0.0024 0.0041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0028 0.0028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0058 0.0034 0.0121
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0048 0.0024 0.0041
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0043 0.0043
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.009 0.0069 0.0643
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0048 0.0024 0.0041
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0079 0.0302
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0327 0.0326 0.1237
Trichomonas vaginalis sucrase-isomaltase, putative 0.0082 0.006 0.0246
Schistosoma mansoni cpg binding protein 0.013 0.0113 0.0113
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0008 0.0059
Echinococcus granulosus cpg binding protein 0.013 0.0113 0.0113
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.1176
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0008 0.0059
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0059 0.0035 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0431 0.0439 0.0439
Trypanosoma cruzi histone deacetylase, putative 0.0038 0.0012 0.0038
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0004 0.0005
Leishmania major short chain dehydrogenase-like protein 0.0048 0.0024 0.0083
Plasmodium vivax DNA gyrase subunit B, putative 0.0136 0.0118 0.415
Brugia malayi histone deacetylase 1 (HD1) 0.004 0.0014 0.0054
Schistosoma mansoni amine GPCR 0.1367 0.1455 0.1455
Trichomonas vaginalis receptor histidine kinase, putative 0.0136 0.0118 0.0489
Plasmodium vivax hypothetical protein, conserved 0.0136 0.0118 0.415
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Trypanosoma cruzi heat shock protein 85, putative 0.0136 0.0118 0.0445
Onchocerca volvulus Huntingtin homolog 0.0138 0.0121 0.0484
Mycobacterium ulcerans putative regulatory protein 0.0152 0.0136 0.0341
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0043 0.0097
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0058 0.0034 0.0068
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0231 0.0222 0.0915
Echinococcus multilocularis neuropeptides capa receptor 0.084 0.0883 0.0883
Echinococcus granulosus GPCR family 2 0.01 0.0079 0.0079
Brugia malayi Calcitonin receptor-like protein seb-1 0.0315 0.0313 0.1194
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Toxoplasma gondii histone deacetylase HDAC2 0.004 0.0014 0.0117
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0048 0.0024 0.0041
Schistosoma mansoni sodium/chloride dependent transporter 0.0256 0.025 0.025
Onchocerca volvulus 0.0109 0.009 0.0354
Schistosoma mansoni metabotropic glutamate receptor 0.01 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.078 0.0818 0.1848
Loa Loa (eye worm) hypothetical protein 0.0036 0.001 0.0022
Schistosoma mansoni hypothetical protein 0.01 0.0079 0.0079
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0059 0.0035 0.0126
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1638 0.1749 0.1749
Brugia malayi Probable DNA topoisomerase II 0.0136 0.0118 0.0452
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0136 0.0118 0.0293
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.0099 0.0099
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0136 0.0118 0.0489
Plasmodium vivax amine transporter, putative 0.0044 0.0018 0.0588
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0043 0.0043
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0327 0.0326 0.1237
Giardia lamblia PHD finger protein 15 0.0034 0.0008 0.0034
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0048 0.0024 0.0041
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Brugia malayi Histone deacetylase 1 0.004 0.0014 0.0054
Echinococcus granulosus survival motor neuron protein 1 0.0695 0.0725 0.0725
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1526 0.1628 0.6215
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0248 0.0241 0.0241
Onchocerca volvulus 0.0048 0.0024 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Echinococcus multilocularis zinc finger protein 0.0227 0.0217 0.0217
Mycobacterium tuberculosis Conserved protein 0.0136 0.0118 0.0293
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0098 0.0078 0.0078
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0015 0.0015
Echinococcus granulosus fmrfamide receptor 0.084 0.0883 0.0883
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0231 0.0222 0.084
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0327 0.0326 0.1237
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni carbonyl reductase 0.0048 0.0024 0.0024
Mycobacterium leprae putative cytochrome p450 0.0058 0.0034 0.038
Brugia malayi jmjC domain containing protein 0.0111 0.0092 0.035
Schistosoma mansoni inositol monophosphatase 0.0039 0.0014 0.0014
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.084 0.0883 0.0883
Echinococcus multilocularis thioredoxin glutathione reductase 0.0098 0.0077 0.0077
Mycobacterium ulcerans short-chain dehydrogenase 0.0048 0.0024 0.0041
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0136 0.0118 0.0473
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Echinococcus multilocularis serotonin transporter 0.0256 0.025 0.025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0028 0.0028
Schistosoma mansoni microtubule-associated protein tau 0.136 0.1447 0.1447
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0098 0.0078 0.0078
Echinococcus granulosus hypothetical protein 0.2259 0.2423 0.2423
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0161 0.0146 1
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0059 0.0035 0.0144
Mycobacterium leprae conserved hypothetical protein 0.0152 0.0136 0.1984
Echinococcus granulosus thyrotropin releasing hormone receptor 0.084 0.0883 0.0883
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Loa Loa (eye worm) heat shock protein 90 0.0136 0.0118 0.0267
Echinococcus granulosus histone deacetylase 7 0.0038 0.0012 0.0012
Schistosoma mansoni cpg binding protein 0.013 0.0113 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.009 0.0373
Onchocerca volvulus 0.084 0.0883 0.3631
Echinococcus granulosus histone acetyltransferase KAT2B 0.028 0.0275 0.0275
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0021 0.0079
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0059 0.0035 0.0126
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0098 0.0078 0.0298
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0048 0.0024 0.0041
Trichomonas vaginalis maltase-glucoamylase, putative 0.0082 0.006 0.0246
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0154 0.0138 0.052
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0002 0.0004
Toxoplasma gondii carbonyl reductase 1, putative 0.0048 0.0024 0.0208
Plasmodium vivax steroid dehydrogenase, putative 0.0048 0.0024 0.0773
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0048 0.0024 0.0024
Echinococcus granulosus FTZ F1 alpha 0.0052 0.0028 0.0028
Mycobacterium ulcerans oxidoreductase 0.0048 0.0024 0.0041
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0043 0.0164
Loa Loa (eye worm) hypothetical protein 0.061 0.0634 0.1432
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0853 0.0897 0.3419
Loa Loa (eye worm) inositol-1 0.0039 0.0014 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Echinococcus granulosus histone deacetylase 0.0038 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.006 0.0221
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0058 0.0034 0.0068
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0014 0.0014
Echinococcus granulosus serotonin receptor 0.084 0.0883 0.0883
Mycobacterium ulcerans beta-lactamase 0.0109 0.009 0.0217
Trichomonas vaginalis histone deacetylase, putative 0.004 0.0014 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0231 0.0222 0.0915
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0048 0.0024 0.0041
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.009 0.0217
Plasmodium vivax thioredoxin reductase, putative 0.0098 0.0077 0.2693
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0008 0.0033
Mycobacterium tuberculosis Possible oxidoreductase 0.0048 0.0024 0.0041
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.025 0.0243 0.092
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.004 0.0014 0.0058
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.084 0.0883 0.3631
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0136 0.0118 0.0293
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Brugia malayi hypothetical protein 0.0294 0.029 0.1108
Echinococcus multilocularis steroid dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi acetyltransferase, GNAT family protein 0.0294 0.029 0.1107
Brugia malayi nuclear receptor NHR-88 0.0052 0.0028 0.0106
Trypanosoma cruzi heat shock protein 85, putative 0.0136 0.0118 0.0445
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0028 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Giardia lamblia Hypothetical protein 0.0048 0.0024 0.0149
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0054 0.0223
Leishmania major hypothetical protein, conserved 0.0059 0.0035 0.0126
Echinococcus multilocularis histone deacetylase 6 0.0038 0.0012 0.0012
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Echinococcus multilocularis neuropeptide receptor 0.084 0.0883 0.0883
Toxoplasma gondii hypothetical protein 0.0044 0.0018 0.0158
Echinococcus multilocularis neutral alpha glucosidase AB 0.0082 0.006 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0048 0.0024 0.0097
Echinococcus granulosus 6 phosphofructokinase 0.011 0.009 0.009
Trichomonas vaginalis histone deacetylase, putative 0.004 0.0014 0.0058
Loa Loa (eye worm) hypothetical protein 0.0103 0.0082 0.0186
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Echinococcus granulosus g protein coupled receptor 0.084 0.0883 0.0883
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0048 0.0024 0.0024
Echinococcus granulosus orexin receptor type 2 0.084 0.0883 0.0883
Plasmodium falciparum histone deacetylase 1 0.004 0.0014 0.0842
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Brugia malayi Muscleblind-like protein 0.061 0.0634 0.242
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0018 0.007
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0018 0.0018
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0058 0.0034 0.0068
Plasmodium vivax endoplasmin, putative 0.0136 0.0118 0.415
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0014 0.0056
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Mycobacterium ulcerans putative regultory protein 0.0136 0.0118 0.0293
Echinococcus granulosus alpha 1A adrenergic receptor 0.084 0.0883 0.0883
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.009 0.009
Giardia lamblia Pms1-like protein 0.0136 0.0118 0.0846
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0048 0.0024 0.0081
Leishmania major hypothetical protein, conserved 0.0034 0.0009 0.0026
Echinococcus multilocularis serotonin receptor 0.4105 0.4426 0.4426
Echinococcus multilocularis GPCR, family 2 0.01 0.0079 0.0079
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0048 0.0024 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0422 0.0429 0.1769
Echinococcus granulosus histone acetyltransferase KAT2B 0.009 0.0069 0.0069
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.006 0.0246
Onchocerca volvulus 0.084 0.0883 0.3631
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0136 0.0118 0.8063
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Brugia malayi Cytochrome P450 family protein 0.0058 0.0034 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.0028 0.0106
Brugia malayi ecdysteroid receptor 0.0052 0.0028 0.0106
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0136 0.0118 0.0445
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0248 0.0241 0.0618
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0294 0.029 0.029
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0136 0.0118 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0082 0.006 0.006
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0004 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0138 0.0569
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0059 0.0035 0.0232
Entamoeba histolytica hypothetical protein 0.0145 0.0129 0.0923
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0054 0.3613
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.084 0.0883 0.0883
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.084 0.0883 0.0883
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0058 0.0034 0.0068
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0021 0.0073
Schistosoma mansoni lamin 0.0085 0.0063 0.0063
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0298 0.0294 0.1124
Schistosoma mansoni endoplasmin 0.0136 0.0118 0.0118
Echinococcus multilocularis fmrfamide receptor 0.084 0.0883 0.0883
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Schistosoma mansoni inositol monophosphatase 0.0039 0.0014 0.0014
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0003 0.0014
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0136 0.0118 0.0118
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0058 0.0034 0.0034
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.0042
Entamoeba histolytica phosphofructokinase, putative 0.011 0.009 0.0641
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0008 0.0023
Onchocerca volvulus 0.0212 0.0202 0.0817
Brugia malayi RE15519p 0.084 0.0883 0.337
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0136 0.0118 0.1118
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0059 0.0035 0.0035
Brugia malayi 6-phosphofructokinase 0.011 0.009 0.0346
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0015 0.006
Schistosoma mansoni aldehyde dehydrogenase 0.0306 0.0303 0.0303
Brugia malayi Bromodomain containing protein 0.0093 0.0073 0.0277
Loa Loa (eye worm) hypothetical protein 0.0059 0.0035 0.0079
Mycobacterium leprae Conserved hypothetical protein 0.0058 0.0034 0.038
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Echinococcus granulosus g protein coupled receptor 0.084 0.0883 0.0883
Echinococcus granulosus neuropeptides capa receptor 0.084 0.0883 0.0883
Brugia malayi Pre-SET motif family protein 0.0287 0.0283 0.1079
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.009 0.0217
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Schistosoma mansoni hypothetical protein 0.0142 0.0125 0.0125
Toxoplasma gondii hypothetical protein 0.0152 0.0136 0.1291
Loa Loa (eye worm) histone methyltransferase 0.0047 0.0023 0.0051
Trichomonas vaginalis ap endonuclease, putative 0.0076 0.0054 0.0223
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0008 0.0422
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0048 0.0024 0.0041
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0059 0.0035 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0035 0.0144
Onchocerca volvulus 0.0044 0.0018 0.0059
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0154 0.0138 0.052
Toxoplasma gondii GAF domain-containing protein 0.0152 0.0136 0.1291
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0003 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0161 0.0146 0.2139
Onchocerca volvulus 0.0048 0.0024 0.0081
Schistosoma mansoni eyes absent homolog 0.0085 0.0064 0.0064
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0048 0.0024 0.0225
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0048 0.0024 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.0028 0.0063
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0082 0.0082
Schistosoma mansoni neuropeptide receptor 0.084 0.0883 0.0883
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0035 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0058 0.0034 0.0068
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0315 0.0313 0.1194
Onchocerca volvulus 0.0103 0.0082 0.0324
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.0256 0.025 0.0564
Leishmania major trypanothione reductase 0.0098 0.0077 0.0289
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0248 0.0241 0.0241
Brugia malayi PHD-finger family protein 0.007 0.0047 0.018
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0012 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0014 0.0056
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0021 0.0073
Echinococcus granulosus hypothetical protein 0.0048 0.0024 0.0024
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.0109 0.009 0.0217
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Mycobacterium leprae Probable two component sensor kinase MprB 0.0136 0.0118 0.1702
Echinococcus multilocularis histone deacetylase 6 0.0038 0.0012 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.084 0.0883 0.0883
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.009 0.009
Plasmodium vivax DNA topoisomerase II, putative 0.0136 0.0118 0.415
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0076 0.0054 0.02
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0154 0.0138 0.052
Chlamydia trachomatis endonuclease IV 0.0161 0.0146 1
Plasmodium vivax importin-beta 2, putative 0.003 0.0003 0.0056
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0082 0.006 0.0554
Loa Loa (eye worm) hypothetical protein 0.0034 0.0008 0.0018
Echinococcus granulosus sex peptide receptor 0.084 0.0883 0.0883
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Echinococcus multilocularis snurportin 1 0.0318 0.0316 0.0316
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.084 0.0883 0.0883
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.0028 0.0028
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0048 0.0024 0.0225
Plasmodium falciparum thioredoxin reductase 0.0034 0.0008 0.0422
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0081 0.0059 0.0059
Plasmodium falciparum phd finger protein, putative 0.0034 0.0008 0.0421
Echinococcus multilocularis G-protein coupled receptor, putative 0.084 0.0883 0.0883
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0048 0.0024 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0035 0.0126
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.009 0.0069 0.0643
Echinococcus multilocularis neuropeptide Y receptor 0.084 0.0883 0.0883
Brugia malayi Cytochrome P450 family protein 0.0133 0.0115 0.044
Echinococcus granulosus thioredoxin glutathione reductase 0.0098 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0039 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.009 0.0203
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.084 0.0883 0.0883
Schistosoma mansoni chromobox protein 0.0074 0.0051 0.0051
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0072 0.0164
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.025 0.0243 0.0548
Echinococcus multilocularis tumor protein p63 0.0701 0.0732 0.0732
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.0028 0.0063
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0001 0.0001
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0059 0.0035 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0008 0.0023
Onchocerca volvulus 0.0048 0.0024 0.0081
Plasmodium vivax phosphodiesterase gamma, putative 0.0059 0.0035 0.1176
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Entamoeba histolytica phosphofructokinase, putative 0.011 0.009 0.0641
Loa Loa (eye worm) hypothetical protein 0.0431 0.0439 0.0992
Echinococcus granulosus neuropeptide receptor A26 0.2264 0.2429 0.2429
Brugia malayi glutathione reductase 0.0098 0.0077 0.0296
Trypanosoma brucei heat shock protein 90, putative 0.0136 0.0118 0.0445
Trypanosoma cruzi ISWI complex protein 0.0034 0.0009 0.0026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0018 0.0018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.0208
Onchocerca volvulus Alhambra homolog 0.0034 0.0008 0.0016
Mycobacterium ulcerans two component sensor kinase MprB 0.0136 0.0118 0.0293
Echinococcus granulosus histone deacetylase 6 0.0038 0.0012 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0907 0.0955 0.0955
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0015 0.0048
Plasmodium falciparum glutathione reductase 0.0034 0.0008 0.0422
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0015 0.0015
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.0126
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0003 0.0045
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Plasmodium falciparum endoplasmin, putative 0.0136 0.0118 0.8063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0014 0.0056
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0136 0.0118 0.0293
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0059 0.0035 0.0126
Plasmodium vivax histone deacetylase, putative 0.0038 0.0012 0.0355
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0014 0.0056
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0076 0.0054 0.02
Brugia malayi dehydrogenases, short chain protein 9 0.0048 0.0024 0.009
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Schistosoma mansoni heat shock protein 0.0136 0.0118 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0015 0.0015
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0367 0.037 0.0836
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0642 0.0668 0.0668
Echinococcus granulosus lysosomal alpha glucosidase 0.0367 0.037 0.037
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0048 0.0024 0.0024
Plasmodium falciparum GAF domain-related protein, putative 0.0152 0.0136 0.9312
Schistosoma mansoni lamin 0.0085 0.0063 0.0063
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0042 0.0017 0.0054
Brugia malayi hypothetical protein 0.0138 0.0121 0.0463
Treponema pallidum sodium- and chloride- dependent transporter 0.0256 0.025 0.1811
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0048 0.0024 0.0041
Schistosoma mansoni aldehyde dehydrogenase 0.0306 0.0303 0.0303
Toxoplasma gondii hypothetical protein 0.0152 0.0136 0.1291
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0076 0.0054 0.186
Mycobacterium ulcerans epimerase 0.0042 0.0017 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0058 0.0034 0.0068
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0051 0.0116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Plasmodium falciparum glutathione reductase 0.0098 0.0077 0.5232
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0035 0.0126
Trypanosoma brucei protein kinase, putative 0.0154 0.0138 0.052
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0048 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0083
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0988 0.1044 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.084 0.0883 0.0883
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0059 0.0035 0.0126
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.084 0.0883 0.0883
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0098 0.0078 0.0078
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0154 0.0138 0.052
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Brugia malayi Cytochrome P450 family protein 0.0093 0.0072 0.0276
Schistosoma mansoni hypothetical protein 0.084 0.0883 0.0883
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0058 0.0034 0.0068
Mycobacterium tuberculosis Probable reductase 0.0224 0.0214 0.0546
Entamoeba histolytica acetyltransferase, GNAT family 0.0078 0.0055 0.0383
Brugia malayi Glycosyl hydrolases family 31 protein 0.003 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.005 0.005
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0083
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.009 0.0371
Brugia malayi beta-lactamase family protein 0.0109 0.009 0.0343
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0018 0.0018
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.084 0.0883 0.337
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Entamoeba histolytica hypothetical protein 0.0145 0.0129 0.0923
Entamoeba histolytica phosphofructokinase, putative 0.011 0.009 0.0641
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0058 0.0034 0.0068
Echinococcus multilocularis lamin dm0 0.0085 0.0063 0.0063
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0001 0.0001
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0048 0.0024 0.0083
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0024 0.0773
Brugia malayi Melatonin receptor type 1A 0.084 0.0883 0.337
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.0028 0.0028
Schistosoma mansoni glutaminase 0.0559 0.0578 0.0578
Brugia malayi jmjC domain containing protein 0.0052 0.0028 0.0106
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.0158
Echinococcus multilocularis dnaJ subfamily B 0.1277 0.1357 0.1357
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0003 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Echinococcus multilocularis neuropeptide receptor A26 0.2264 0.2429 0.2429
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.0139 0.0524
Loa Loa (eye worm) hypothetical protein 0.0215 0.0205 0.0462
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.009 0.0339
Giardia lamblia Fructose-bisphosphate aldolase 0.1282 0.1362 1
Echinococcus granulosus histone deacetylase 6 0.0038 0.0012 0.0012
Echinococcus multilocularis tachykinin peptides receptor 99D 0.084 0.0883 0.0883
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0047 0.0023 0.0023
Echinococcus granulosus bloom syndrome protein 0.0044 0.0018 0.0018
Echinococcus granulosus mitogen activated protein kinase 14 0.025 0.0243 0.0243
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0154 0.0138 0.0312
Echinococcus multilocularis orexin receptor type 2 0.084 0.0883 0.0883
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0136 0.0118 0.0293
Trichomonas vaginalis histone deacetylase, putative 0.004 0.0014 0.0058
Trypanosoma brucei trypanothione reductase 0.0098 0.0077 0.0289
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0016 0.005
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Echinococcus granulosus histone deacetylase 1 0.004 0.0014 0.0014
Loa Loa (eye worm) TYRA-2 protein 0.084 0.0883 0.1994
Brugia malayi Stress-activated protein kinase jnk-1 0.0907 0.0955 0.3648
Loa Loa (eye worm) hypothetical protein 0.0325 0.0324 0.0733
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0383 0.0387 0.1472
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0017 0.0025
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0248 0.0241 0.0618
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0058 0.0034 0.0034
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus multilocularis steroid dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi Dopamine receptor protein 1 0.1305 0.1388 0.5299
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0048 0.0024 0.0083
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.009 0.0371
Loa Loa (eye worm) cytochrome P450 0.0058 0.0034 0.0076
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0058 0.0034 0.0121
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0008 0.0008
Giardia lamblia Histone deacetylase 0.004 0.0014 0.0079
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0048 0.0024 0.0097
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0014 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0058 0.0034 0.0068
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.009 0.0217
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.2439 0.2619 0.2619
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Plasmodium falciparum heat shock protein 90 0.0136 0.0118 0.8063
Brugia malayi gonadotropin-releasing hormone receptor 2 0.084 0.0883 0.337
Leishmania major short chain dehydrogenase/reductase, putative 0.0048 0.0024 0.0083
Onchocerca volvulus 0.0462 0.0472 0.1936
Trypanosoma cruzi histone deacetylase, putative 0.0038 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0018 0.0588
Loa Loa (eye worm) endoplasmin 0.0136 0.0118 0.0267
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.084 0.0883 0.0883
Toxoplasma gondii aldehyde dehydrogenase 0.0306 0.0303 0.2893
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0058 0.0034 0.0068
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.007 0.0047 0.0434
Onchocerca volvulus 0.0048 0.0024 0.0081
Loa Loa (eye worm) acetyltransferase 0.0294 0.029 0.0655
Loa Loa (eye worm) hypothetical protein 0.0031 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0085 0.0063 0.0143
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.084 0.0883 0.0883
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Mycobacterium ulcerans dehydrogenase/reductase 0.0048 0.0024 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0004 0.0017
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Loa Loa (eye worm) hypothetical protein 0.004 0.0014 0.0032
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0018 0.1049
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.2286
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0008 0.0033
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0003 0.0015
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0853 0.0897 0.3419
Echinococcus granulosus hypothetical protein 0.0048 0.0024 0.0024
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0048 0.0024 0.0149
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0003 0.0014
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Mycobacterium tuberculosis Conserved protein 0.0109 0.009 0.0217
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.025 0.0243 0.092
Trypanosoma cruzi heat shock protein 90, putative 0.0136 0.0118 0.0445
Brugia malayi hypothetical protein 0.0044 0.0018 0.007
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.084 0.0883 0.0883
Onchocerca volvulus 0.0052 0.0028 0.0098
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0003 0.0053
Onchocerca volvulus 0.0142 0.0125 0.05
Loa Loa (eye worm) hypothetical protein 0.0138 0.0121 0.0274
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0016 0.0016
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Brugia malayi PHD-finger family protein 0.0034 0.0008 0.003
Brugia malayi Fli-1 protein 0.0219 0.0209 0.0799
Schistosoma mansoni alpha-glucosidase 0.0316 0.0314 0.0314
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Trichomonas vaginalis maltase-glucoamylase, putative 0.003 0.0004 0.0017
Trichomonas vaginalis esterase, putative 0.0109 0.009 0.0371
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0154 0.0138 0.052
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0698 0.0729 0.1915
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0059 0.0035 0.0035
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0136 0.0118 0.0293
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.009 0.0373
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0008 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0015 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0083
Leishmania major histone deacetylase, putative 0.004 0.0014 0.0046
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Echinococcus multilocularis lysosomal alpha glucosidase 0.0367 0.037 0.037
Brugia malayi dehydrogenases, short chain protein 2 0.0048 0.0024 0.009
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0136 0.0118 0.0293
Schistosoma mansoni hypothetical protein 0.0034 0.0009 0.0009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Trypanosoma cruzi heat shock protein 90, putative 0.0136 0.0118 0.0445
Brugia malayi MBOAT family protein 0.0248 0.0241 0.0919
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.084 0.0883 0.1994
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0431 0.0439 0.1677
Toxoplasma gondii histone deacetylase HDAC1 0.0038 0.0012 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0015 0.006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1282 0.1362 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0076 0.0054 0.0054
Echinococcus granulosus neuropeptide s receptor 0.2264 0.2429 0.2429
Brugia malayi Heterochromatin protein 1 0.0074 0.0051 0.0196
Echinococcus multilocularis allatostatin A receptor 0.084 0.0883 0.0883
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0642 0.0668 0.2551
Plasmodium vivax glutathione reductase, putative 0.0098 0.0077 0.2693
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.002
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Loa Loa (eye worm) histone deacetylase 1 0.004 0.0014 0.0032
Mycobacterium tuberculosis Probable oxidoreductase 0.0048 0.0024 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0211 0.02 0.0826
Leishmania major C-8 sterol isomerase-like protein 0.1526 0.1628 0.6213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Mycobacterium tuberculosis Probable oxidoreductase 0.0048 0.0024 0.0041
Onchocerca volvulus 0.0119 0.0101 0.0399
Mycobacterium ulcerans ketoacyl reductase 0.0048 0.0024 0.0041
Entamoeba histolytica short chain dehydrogenase family protein 0.0048 0.0024 0.0149
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0014 0.0113
Trypanosoma brucei histone deacetylase, putative 0.0038 0.0012 0.0038
Echinococcus granulosus snurportin 1 0.0318 0.0316 0.0316
Mycobacterium ulcerans short-chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus granulosus muscleblind protein 0.061 0.0634 0.0634
Echinococcus multilocularis somatostatin receptor 0.084 0.0883 0.0883
Echinococcus multilocularis oxidoreductase 0.0048 0.0024 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0058 0.0034 0.0068
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0136 0.0118 0.0445
Mycobacterium tuberculosis Probable dehydrogenase 0.0224 0.0214 0.0546
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0048 0.0024 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.006 0.0246
Loa Loa (eye worm) hypothetical protein 0.0159 0.0144 0.0326
Brugia malayi G-protein coupled receptor 0.084 0.0883 0.337
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Onchocerca volvulus 0.084 0.0883 0.3631
Loa Loa (eye worm) hypothetical protein 0.2439 0.2619 0.5916
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.009 0.0373
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0145 0.0129 0.0129
Onchocerca volvulus Putative nachr subunit 0.0098 0.0078 0.0306
Loa Loa (eye worm) serotonin transporter b 0.0256 0.025 0.0564
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0136 0.0118 0.0452
Loa Loa (eye worm) melatonin receptor type 1A 0.084 0.0883 0.1994
Loa Loa (eye worm) hypothetical protein 0.0298 0.0294 0.0665
Onchocerca volvulus Huntingtin homolog 0.0138 0.0121 0.0484
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0059 0.0035 0.0126
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0043 0.0043
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.0028 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus granulosus lamin dm0 0.0085 0.0063 0.0063
Brugia malayi Bromodomain containing protein 0.0183 0.017 0.0648
Trichomonas vaginalis DNA topoisomerase II, putative 0.0136 0.0118 0.0489
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.007
Echinococcus multilocularis heat shock protein 0.0136 0.0118 0.0118
Trichomonas vaginalis chromobox protein, putative 0.0045 0.002 0.008
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.0028 0.0106
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0003 0.0053
Onchocerca volvulus 0.0044 0.0018 0.0059
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.0028 0.0028
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0147 0.013 0.013
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0138 0.0569
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0059 0.0035 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0076 0.0054 0.0373
Trichomonas vaginalis histone deacetylase, putative 0.004 0.0014 0.0058
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0004 0.0017
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.009 0.0373
Loa Loa (eye worm) phosphofructokinase 0.011 0.009 0.0204
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0138 0.0138
Schistosoma mansoni opsin-like receptor 0.084 0.0883 0.0883
Schistosoma mansoni myosin xvIII 0.084 0.0883 0.0883
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0014 0.0045
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0048 0.0024 0.0149
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Schistosoma mansoni hypothetical protein 0.01 0.0079 0.0079
Echinococcus multilocularis histone deacetylase 7 0.0038 0.0012 0.0012
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0853 0.0897 0.3419
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Echinococcus granulosus retinol dehydrogenase 11 0.0048 0.0024 0.0024
Brugia malayi MH2 domain containing protein 0.037 0.0373 0.1423
Schistosoma mansoni jumonji/arid domain-containing protein 0.0052 0.0028 0.0028
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.002 0.0064
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Onchocerca volvulus 0.0048 0.0024 0.0081
Echinococcus granulosus g-protein coupled receptor 0.084 0.0883 0.0883
Leishmania major glycosyl hydrolase-like protein 0.003 0.0004 0.0008
Leishmania major 3-keto-dihydrosphingosine reductase 0.0048 0.0024 0.0083
Schistosoma mansoni importin beta-1 0.003 0.0003 0.0003
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.2439 0.2619 0.2619
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.009 0.0336
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi nuclear hormone receptor 0.0052 0.0028 0.0106
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0014 0.0045
Schistosoma mansoni lipoxygenase 0.0118 0.0099 0.0099
Loa Loa (eye worm) CYP4Cod1 0.0093 0.0072 0.0164
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0008 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0008 0.0422
Trypanosoma brucei developmentally regulated phosphoprotein 0.2439 0.2619 1
Schistosoma mansoni hypothetical protein 0.0215 0.0205 0.0205
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0048 0.0024 0.0149
Schistosoma mansoni alpha glucosidase 0.0082 0.006 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0014 0.0045
Schistosoma mansoni gabp alpha 0.0072 0.005 0.005
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.004 0.0014 0.0058
Trichomonas vaginalis receptor histidine kinase, putative 0.0136 0.0118 0.0489
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0032 0.0115
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0008 0.0216
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0383 0.0387 0.1472
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0035 0.0144
Brugia malayi Dehydrogenases, short chain protein 2 0.0048 0.0024 0.009
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0059 0.0035 0.0035
Loa Loa (eye worm) dehydrogenase 0.0048 0.0024 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0014 0.0056
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0136 0.0118 0.0293
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) histone deacetylase 3 0.004 0.0014 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.3504 0.3774 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.007
Schistosoma mansoni carbonyl reductase 0.0048 0.0024 0.0024
Schistosoma mansoni pyruvate dehydrogenase 0.2304 0.2471 0.2471
Echinococcus granulosus steroid dehydrogenase 0.0048 0.0024 0.0024
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0059 0.0035 0.0079
Leishmania major cytochrome p450-like protein 0.0093 0.0072 0.0269
Echinococcus granulosus methyl CpG binding domain protein 2 0.0038 0.0013 0.0013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.084 0.0883 0.0883
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0028 0.0106
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0048 0.0024 0.0208
Schistosoma mansoni hypothetical protein 0.084 0.0883 0.0883
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1718 0.1836 0.1836
Brugia malayi hypothetical protein 0.0252 0.0245 0.0935
Loa Loa (eye worm) intermediate filament protein 0.0085 0.0063 0.0143
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0015 0.0055
Trypanosoma brucei ISWI complex protein 0.0034 0.0009 0.0026
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0014 0.0056
Onchocerca volvulus 0.0048 0.0024 0.0081
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0042 0.0017 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Echinococcus granulosus heat shock protein 90 0.0136 0.0118 0.0118
Loa Loa (eye worm) solute carrier family 6 member 4 0.0256 0.025 0.0564
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0048 0.0024 0.0081
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Mycobacterium ulcerans two component regulator - sensor kinase 0.0136 0.0118 0.0293
Trypanosoma brucei short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0024 0.1503
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0059 0.0035 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0058 0.0034 0.0068
Brugia malayi G protein-coupled receptor 0.084 0.0883 0.337
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0058 0.0034 0.0068
Brugia malayi nuclear receptor RXR 0.0028 0.0001 0.0004
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.009 0.0217
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0048 0.0024 0.0083
Onchocerca volvulus 0.0109 0.009 0.0354
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.0028 0.0063
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.0028 0.0028
Echinococcus granulosus 7TM GPCR rhodopsin 0.084 0.0883 0.0883
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.0077 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.0136 0.0563
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0024 0.0149
Echinococcus granulosus cytochrome P450 2K1 0.0058 0.0034 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Brugia malayi phosphofructokinase 0.011 0.009 0.0346
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Echinococcus granulosus expressed protein 0.0364 0.0366 0.0366
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Loa Loa (eye worm) glutamate receptor 0.0047 0.0022 0.005
Trichomonas vaginalis endoplasmin, putative 0.0136 0.0118 0.0489
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0038 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Plasmodium falciparum DNA topoisomerase 2 0.0136 0.0118 0.8063
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0059 0.0035 0.0133
Schistosoma mansoni hypothetical protein 0.0318 0.0316 0.0316
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0058 0.0034 0.0068
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Echinococcus granulosus allatostatin A receptor 0.084 0.0883 0.0883
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi metabotropic glutamate receptor type 2 0.0058 0.0034 0.013
Onchocerca volvulus 0.084 0.0883 0.3631
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0059 0.0035 0.2286
Onchocerca volvulus 0.0048 0.0024 0.0081
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0038 0.0013 0.0042
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0136 0.0118 0.0293
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Entamoeba histolytica heat shock protein 90, putative 0.0136 0.0118 0.0846
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) hypothetical protein 0.0105 0.0085 0.0191
Brugia malayi hypothetical protein 0.0145 0.0129 0.0492
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.006 0.0221
Brugia malayi Histone deacetylase family protein 0.0038 0.0012 0.0045
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Brugia malayi histone deacetylase 3 (HD3) 0.004 0.0014 0.0054
Onchocerca volvulus 0.0085 0.0063 0.0245
Echinococcus multilocularis 0.0058 0.0034 0.0034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0014 0.0056
Loa Loa (eye worm) hypothetical protein 0.0136 0.0118 0.0267
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0138 0.0569
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0043 0.0043
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0136 0.0118 0.0489
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0008 0.0023
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.0042
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.0028 0.0028
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.0139 0.0524
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0154 0.0138 0.052
Plasmodium vivax histone deacetylase 2, putative 0.0038 0.0012 0.0355
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.009 0.009
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0211 0.02 0.0826
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0008 0.0034
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0048 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0024 0.0083
Trichomonas vaginalis histone deacetylase, putative 0.004 0.0014 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Mycobacterium tuberculosis Probable oxidoreductase 0.3504 0.3774 1
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0009
Trypanosoma cruzi short chain dehydrogenase, putative 0.0048 0.0024 0.0083
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0657 0.0685 0.1547
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) fli-1 protein 0.0219 0.0209 0.0473
Trypanosoma brucei short-chain dehydrogenase, putative 0.0048 0.0024 0.0083
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0008 0.0023
Entamoeba histolytica DNA topoisomerase II, putative 0.0136 0.0118 0.0846
Mycobacterium ulcerans ketoacyl reductase 0.0048 0.0024 0.0041
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0028 0.0106
Schistosoma mansoni zinc finger protein 0.0058 0.0034 0.0034
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.025 0.0243 0.092
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0008 0.0008
Schistosoma mansoni metabotropic glutamate receptor 0.0058 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.1114 0.1181 0.2667
Chlamydia trachomatis DNA gyrase subunit B 0.0136 0.0118 0.8043
Loa Loa (eye worm) hypothetical protein 0.0294 0.029 0.0655
Onchocerca volvulus 0.0048 0.0024 0.0081
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0287 0.0283 0.0283
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0058 0.0034 0.0068
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Onchocerca volvulus 0.084 0.0883 0.3631
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0076 0.0054 0.0122
Schistosoma mansoni retinal dehydrogenase 0.0048 0.0024 0.0024
Mycobacterium leprae Probable lipase LipE 0.0109 0.009 0.1256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.0028 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0016 0.0066
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.009 0.0217
Schistosoma mansoni neuropeptide F-like receptor 0.084 0.0883 0.0883
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0306 0.0303 0.0303
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0018 0.0158
Schistosoma mansoni neuropeptide receptor 0.924 1 1
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Mycobacterium tuberculosis Conserved hypothetical protein 0.0172 0.0158 0.0398
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0059 0.0035 0.0035
Echinococcus granulosus neuropeptide receptor 0.084 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.0059 0.0035 0.0079
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0001 0.0001
Loa Loa (eye worm) histone deacetylase 0.0038 0.0012 0.0027
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0015 0.0048
Onchocerca volvulus 0.084 0.0883 0.3631
Trichomonas vaginalis steroid dehydrogenase, putative 0.0048 0.0024 0.0097
Echinococcus multilocularis carbonyl reductase 1 0.0048 0.0024 0.0024
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0042 0.0017 0.0025
Echinococcus multilocularis mitogen activated protein kinase 0.0154 0.0138 0.0138
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0431 0.0439 0.0439
Echinococcus multilocularis retinol dehydrogenase 13 0.0048 0.0024 0.0024
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Echinococcus granulosus heat shock protein 0.0136 0.0118 0.0118
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.005 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Onchocerca volvulus 0.0256 0.025 0.1014
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0082 0.006 0.0135
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0287 0.0283 0.2694
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0145 0.0129 0.0129
Schistosoma mansoni biogenic amine (5HT) receptor 0.1638 0.1749 0.1749
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0003 0.0006
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0136 0.0118 0.0846
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0048 0.0024 0.0041
Mycobacterium leprae conserved hypothetical protein 0.0109 0.009 0.1256
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0048 0.0024 0.009
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0108 0.0088 0.0337
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0021 0.0073
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Echinococcus multilocularis heat shock protein 90 0.0136 0.0118 0.0118
Mycobacterium ulcerans short-chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus multilocularis conserved hypothetical protein 0.0048 0.0024 0.0024
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0383 0.0387 0.1597
Schistosoma mansoni ets-related 0.0219 0.0209 0.0209
Schistosoma mansoni histone deacetylase 0.004 0.0014 0.0014
Echinococcus granulosus chromobox protein 1 0.0074 0.0051 0.0051
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0003 0.0014
Echinococcus granulosus mitogen activated protein kinase 0.0154 0.0138 0.0138
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0161 0.0146 0.0559
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Brugia malayi GnHR receptor homolog 0.084 0.0883 0.337
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0048 0.0024 0.0041
Echinococcus multilocularis chromobox protein 1 0.0074 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0099 0.0078 0.0177
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0083
Mycobacterium ulcerans DNA gyrase subunit B 0.0136 0.0118 0.0293
Leishmania major hypothetical protein, conserved 0.0038 0.0013 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0299 0.0296 0.0296
Brugia malayi Dopamine receptor protein 2 0.084 0.0883 0.337
Schistosoma mansoni ap endonuclease 0.0076 0.0054 0.0054
Plasmodium vivax heat shock protein 86, putative 0.0136 0.0118 0.415
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0058 0.0034 0.0068
Loa Loa (eye worm) MH2 domain-containing protein 0.037 0.0373 0.0842
Trichomonas vaginalis bromodomain-containing protein, putative 0.009 0.0069 0.0284
Leishmania major ATP-dependent phosphofructokinase 0.011 0.009 0.0339
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0224 0.0214 0.0546
Trypanosoma cruzi histone deacetylase 1, putative 0.004 0.0014 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0059 0.0035 0.0035
Echinococcus granulosus histone lysine methyltransferase setb 0.0325 0.0324 0.0324
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.084 0.0883 0.0883
Schistosoma mansoni cytochrome P450 0.0058 0.0034 0.0034
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.0028 0.0098
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0048 0.0024 0.0083
Brugia malayi hypothetical protein 0.0028 0.0001 0.0004
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) runx1 0.0058 0.0034 0.0077
Echinococcus multilocularis Protein lozenge 0.0058 0.0034 0.0034
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0012 0.0026
Echinococcus multilocularis musashi 0.0085 0.0063 0.0063
Loa Loa (eye worm) glutaminase 2 0.0559 0.0578 0.1306
Schistosoma mansoni hypothetical protein 0.0047 0.0022 0.0022
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0015 0.0082
Trypanosoma brucei glycosyl hydrolase-like protein 0.003 0.0004 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.0048 0.0024 0.0024
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Onchocerca volvulus 0.0109 0.009 0.0354
Echinococcus granulosus zinc finger protein 0.0227 0.0217 0.0217
Echinococcus granulosus importin subunit beta 1 0.003 0.0003 0.0003
Toxoplasma gondii DNA topoisomerase 2, putative 0.0136 0.0118 0.1118
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Loa Loa (eye worm) hypothetical protein 0.0161 0.0146 0.0331
Leishmania major pteridine reductase 1 0.0048 0.0024 0.0083
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0022 0.0022
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0136 0.0118 0.0293
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0048 0.0024 0.0208
Brugia malayi Importin beta-1 subunit 0.003 0.0003 0.0013
Echinococcus granulosus mitogen activated protein kinase 3 0.0154 0.0138 0.0138
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0136 0.0118 0.0489
Loa Loa (eye worm) neuropeptide F receptor 0.084 0.0883 0.1994
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0642 0.0668 0.0668
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0048 0.0024 0.0083
Chlamydia trachomatis DNA gyrase subunit B 0.0136 0.0118 0.8043
Schistosoma mansoni biogenic amine receptor 0.084 0.0883 0.0883
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus multilocularis dro:myosuppressin receptor 0.084 0.0883 0.0883
Plasmodium falciparum thioredoxin reductase 0.0098 0.0077 0.5232
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3537 0.381 0.381
Schistosoma mansoni biogenic amine (dopamine) receptor 0.084 0.0883 0.0883
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.0144
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0058 0.0034 0.0068
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0018 0.0018
Leishmania major cAMP-specific phosphodiesterase, putative 0.0059 0.0035 0.0126
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0154 0.0138 0.1306
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.0028 0.0106
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0048 0.0024 0.0024
Brugia malayi P38 map kinase family protein 2 0.025 0.0243 0.0927
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0021 0.0073
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0058 0.0034 0.0068
Mycobacterium ulcerans short-chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.0028 0.0028
Echinococcus granulosus fetal alzheimer antigen falz 0.0058 0.0034 0.0034
Echinococcus multilocularis cpg binding protein 0.013 0.0113 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Trypanosoma cruzi cytochrome P450, putative 0.0093 0.0072 0.0269
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0136 0.0118 0.0445
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0383 0.0387 0.1472
Mycobacterium leprae Probable two-component sensor kinase 0.0136 0.0118 0.1702
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0076 0.0054 0.4176
Loa Loa (eye worm) hypothetical protein 0.0109 0.009 0.0203
Schistosoma mansoni pyruvate dehydrogenase 0.2304 0.2471 0.2471
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0037 0.0012 0.0044
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0014 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0462 0.0472 0.1067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2378 0.2552 0.2552
Brugia malayi heat shock protein 90 0.0136 0.0118 0.0452
Schistosoma mansoni survival motor neuron protein 0.0142 0.0125 0.0125
Echinococcus multilocularis neuropeptide FF receptor 2 0.084 0.0883 0.0883
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0248 0.0241 0.3611
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0136 0.0118 0.0293
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1282 0.1362 0.5621
Mycobacterium ulcerans oxidoreductase 0.0048 0.0024 0.0041
Schistosoma mansoni neuropeptide F-like receptor 0.084 0.0883 0.0883
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0048 0.0024 0.0041
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0038 0.0013 0.0042
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus granulosus neuropeptides capa receptor 0.084 0.0883 0.0883
Brugia malayi Metabotropic glutamate receptor precursor. 0.0119 0.01 0.0384
Loa Loa (eye worm) hypothetical protein 0.1526 0.1628 0.3677
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0853 0.0897 0.8587
Brugia malayi steroid hormone receptor 0.0052 0.0028 0.0106
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0034 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0028 0.0106
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0136 0.0118 0.0445
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0048 0.0024 0.0024
Echinococcus granulosus carbonyl reductase 1 0.0048 0.0024 0.0024
Leishmania major hypothetical protein, conserved 0.0136 0.0118 0.0445
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0048 0.0024 0.009
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.4105 0.4426 1
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0024 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0138 0.0569
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0076 0.0054 0.0054
Echinococcus granulosus lamin 0.0085 0.0063 0.0063
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0048 0.0024 0.0041
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Schistosoma mansoni hypothetical protein 0.0347 0.0347 0.0347
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0298 0.0294 0.0294
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0015 0.0082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Loa Loa (eye worm) hypothetical protein 0.0042 0.0017 0.0039
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0015 0.0015
Echinococcus multilocularis carbonyl reductase 1 0.0048 0.0024 0.0024
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.005 0.0112
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0148 0.0132 0.0132
Toxoplasma gondii heat shock protein 90, putative 0.0136 0.0118 0.1118
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0431 0.0439 0.0439
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0058 0.0034 0.0068
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Mycobacterium tuberculosis Probable dehydrogenase 0.0048 0.0024 0.0041
Treponema pallidum fructose-bisphosphate aldolase 0.1282 0.1362 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0003 0.0014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0136 0.0118 1
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0136 0.0118 0.0489
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0018 0.0018
Onchocerca volvulus 0.0048 0.0024 0.0081
Brugia malayi chromobox protein homolog 3 0.0041 0.0016 0.0061
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0325 0.0324 0.0324
Brugia malayi kinase, mitochondrial precursor 0.2439 0.2619 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.4105 0.4426 0.4426
Loa Loa (eye worm) hypothetical protein 0.0109 0.009 0.0203
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0135 0.0118 0.0118
Brugia malayi Dopamine receptor 0.084 0.0883 0.337
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0383 0.0387 0.0387
Echinococcus granulosus serotonin transporter 0.0256 0.025 0.025
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0048 0.0024 0.1414
Echinococcus multilocularis g protein coupled receptor 0.084 0.0883 0.0883
Schistosoma mansoni rhodopsin-like orphan GPCR 0.084 0.0883 0.0883
Brugia malayi beta-lactamase 0.0109 0.009 0.0343
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0048 0.0024 0.0149
Mycobacterium tuberculosis Probable oxidoreductase 0.0048 0.0024 0.0041
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0014
Trypanosoma brucei heat shock protein, putative 0.0136 0.0118 0.0445
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0136 0.0118 0.0445
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0018 0.0071
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0161 0.0146 0.0367
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0383 0.0387 0.0387
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0014 0.0014
Schistosoma mansoni alpha-1 adrenergic receptor 0.084 0.0883 0.0883
Leishmania major quinonoid dihydropteridine reductase 0.0048 0.0024 0.0083
Onchocerca volvulus 0.084 0.0883 0.3631
Echinococcus granulosus carbonyl reductase 1 0.0048 0.0024 0.0024
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.0208
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.00000053848 0.0000022219
Trypanosoma cruzi histone deacetylase 1, putative 0.004 0.0014 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Brugia malayi Serotonin/octopamine receptor family protein 7 0.2083 0.2233 0.8525
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) hypothetical protein 0.0044 0.0018 0.0042
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0058 0.0034 0.0068
Loa Loa (eye worm) hypothetical protein 0.0085 0.0064 0.0144
Trypanosoma brucei Heat shock protein 83, putative 0.0136 0.0118 0.0445
Echinococcus granulosus biogenic amine 5HT receptor 0.4105 0.4426 0.4426
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.0028 0.0106
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0097 0.0077 0.0316
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0048 0.0024 0.0083
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.0063 0.0143
Brugia malayi hypothetical protein 0.0028 0.0002 0.0007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) hypothetical protein 0.0256 0.025 0.0564
Brugia malayi neuropeptide F receptor 0.084 0.0883 0.337
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0059 0.0035 0.0035
Echinococcus multilocularis carbonyl reductase 1 0.0048 0.0024 0.0024
Echinococcus multilocularis metabotropic glutamate receptor 2 0.01 0.0079 0.0079
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.009 0.1267
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0288 0.0284 0.0732
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.006 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0028 0.0106
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0048 0.0024 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.0323 0.1334
Brugia malayi hypothetical protein 0.084 0.0883 0.337
Loa Loa (eye worm) TOPoisomerase family member 0.0136 0.0118 0.0267
Schistosoma mansoni histone deacetylase 0.004 0.0014 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0109 0.0089 0.0368
Loa Loa (eye worm) CXXC zinc finger family protein 0.0119 0.0101 0.0227
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0059 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0062 0.0038 0.0086
Leishmania major histone deacetylase, putative 0.0038 0.0012 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.00000053847 0.0000022219
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0048 0.0024 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0131 0.0113 0.0113
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0058 0.0034 0.0068
Loa Loa (eye worm) hypothetical protein 0.0109 0.009 0.0203
Echinococcus granulosus dro:myosuppressin receptor 0.084 0.0883 0.0883
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0018 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0249 0.0241 0.2298
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0383 0.0387 0.1597
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Leishmania major DNA topoisomerase ii 0.0136 0.0118 0.0445
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.0028 0.0063
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0136 0.0118 0.1118
Mycobacterium ulcerans aldehyde dehydrogenase 0.0306 0.0303 0.0784
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0008 0.0031
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0048 0.0024 0.0083
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0018 0.0018
Mycobacterium leprae Probable oxidoreductase 0.0048 0.0024 0.0225
Echinococcus multilocularis mitogen activated protein kinase 14 0.025 0.0243 0.0243
Mycobacterium ulcerans hypothetical protein 0.0172 0.0158 0.0398
Loa Loa (eye worm) G-protein coupled receptor 0.084 0.0883 0.1994
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.0323 0.1334
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0059 0.0035 0.0035
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0013 0.0751
Plasmodium falciparum phosphodiesterase delta, putative 0.0059 0.0035 0.2286
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0003 0.0103
Trichomonas vaginalis sensor histidine kinase, putative 0.0136 0.0118 0.0489
Brugia malayi Ets-domain containing protein 0.0072 0.005 0.0189
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.009 0.0069 0.0284
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.084 0.0883 0.0883
Echinococcus granulosus peregrin 0.0046 0.0021 0.0021
Echinococcus granulosus histone deacetylase 6 0.0038 0.0012 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0059 0.0035 0.0126
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0079 0.0079
Echinococcus multilocularis g-protein coupled receptor 0.084 0.0883 0.0883
Toxoplasma gondii ABC1 family protein 0.0109 0.009 0.0844
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.006 0.0246
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.009 0.0641
Echinococcus multilocularis G protein coupled receptor 139 0.924 1 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0111 0.0092 0.0092
Trypanosoma cruzi histone deacetylase, putative 0.0038 0.0012 0.0038
Echinococcus granulosus tumor protein p63 0.0701 0.0732 0.0732
Brugia malayi F/Y-rich N-terminus family protein 0.0062 0.0039 0.0148
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0225
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0018 0.0076
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.1176
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.0028 0.0028
Echinococcus multilocularis lysosomal alpha glucosidase 0.0367 0.037 0.037
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.0028 0.0028
Echinococcus granulosus tachykinin peptides receptor 99D 0.084 0.0883 0.0883
Trypanosoma cruzi cytochrome P450, putative 0.0093 0.0072 0.0269
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0013 0.0013
Brugia malayi hypothetical protein 0.0048 0.0024 0.009
Toxoplasma gondii thioredoxin reductase 0.0098 0.0077 0.0726
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.084 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.0087 0.0065 0.0147
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0907 0.0955 0.2158
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0058 0.0034 0.0068
Toxoplasma gondii hypothetical protein 0.0324 0.0323 0.3084
Echinococcus granulosus WW domain containing oxidoreductase 0.0048 0.0024 0.0024
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.012 0.0101 0.0229
Loa Loa (eye worm) hypothetical protein 0.0083 0.0062 0.0139
Leishmania major hypothetical protein, conserved 0.0109 0.009 0.0336
Schistosoma mansoni opsin-like receptor 0.084 0.0883 0.0883
Trypanosoma brucei histone deacetylase 3 0.0038 0.0012 0.0038
Entamoeba histolytica histone deacetylase, putative 0.004 0.0014 0.0079
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0016 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0131 0.0113 0.0113
Echinococcus granulosus c-Jun N-terminal kinases 0.0907 0.0955 0.0955
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0016 0.0016
Brugia malayi CXXC zinc finger family protein 0.0119 0.0101 0.0384
Loa Loa (eye worm) hypothetical protein 0.0039 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0077
Echinococcus multilocularis lamin 0.0085 0.0063 0.0063
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0059 0.0035 0.0035
Toxoplasma gondii oxidoreductase, putative 0.0048 0.0024 0.0208
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.009 0.009
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0018 0.0018
Schistosoma mansoni coup transcription factor 0.0052 0.0028 0.0028
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0136 0.0118 0.0293
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.0144
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0136 0.0118 0.0473
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0008
Treponema pallidum NADH oxidase 0.0034 0.0008 0.0034
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0015 0.0015
Plasmodium falciparum steroid dehydrogenase, putative 0.0048 0.0024 0.1503
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0008 0.0008
Toxoplasma gondii exonuclease III APE 0.0076 0.0054 0.0501
Onchocerca volvulus Sepiapterin reductase homolog 0.0048 0.0024 0.0081
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0136 0.0118 0.0846
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.0028 0.0028
Brugia malayi Pre-SET motif family protein 0.1985 0.2126 0.8119
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0048 0.0024 0.1503
Brugia malayi neuropeptide F receptor 0.084 0.0883 0.337
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0154 0.0138 0.052
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0079 0.0079
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.2439 0.2619 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0014 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Echinococcus granulosus intermediate filament protein 0.0085 0.0063 0.0063
Mycobacterium ulcerans hypothetical protein 0.0109 0.009 0.0217
Schistosoma mansoni hypothetical protein 0.0145 0.0129 0.0129
Echinococcus multilocularis microtubule associated protein 2 0.136 0.1447 0.1447
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Giardia lamblia Histone acetyltransferase GCN5 0.0078 0.0055 0.0383
Schistosoma mansoni lipoxygenase 0.0083 0.0061 0.0061
Schistosoma mansoni lozenge 0.0058 0.0034 0.0034
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0008 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.006 0.0246
Brugia malayi hypothetical protein 0.0048 0.0024 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0035 0.0126
Loa Loa (eye worm) hypothetical protein 0.2083 0.2233 0.5044
Onchocerca volvulus 0.084 0.0883 0.3631
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0028 0.0106
Echinococcus granulosus neuropeptide Y receptor 0.084 0.0883 0.0883
Trichomonas vaginalis glutaminase, putative 0.0559 0.0578 0.2384
Leishmania major oxidoreductase-like protein 0.0048 0.0024 0.0083
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0264 0.0257 0.0257
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Toxoplasma gondii hypothetical protein 0.0053 0.0028 0.0254
Leishmania major short chain dehydrogenase, putative 0.0048 0.0024 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0002
Echinococcus granulosus metabotropic glutamate receptor 5 0.0147 0.013 0.013
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.0004 0.0008
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0059 0.0035 0.0035
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0081 0.0059 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0325 0.0324 0.0324
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0004 0.0017
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.084 0.0883 0.0883
Echinococcus multilocularis peregrin 0.0046 0.0021 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Plasmodium falciparum DNA gyrase subunit B 0.0136 0.0118 0.8063
Loa Loa (eye worm) hypothetical protein 0.0138 0.0121 0.0274
Trypanosoma brucei C-8 sterol isomerase, putative 0.1526 0.1628 0.6213
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0048 0.0024 0.0041
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0051 0.0212
Trypanosoma brucei oxidoreductase-like protein 0.0048 0.0024 0.0083
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0035 0.0317
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Plasmodium falciparum transporter, putative 0.0044 0.0018 0.1142
Leishmania major mitochondrial DNA polymerase beta 0.0327 0.0326 0.1237
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0014 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0058 0.0034 0.0068
Mycobacterium ulcerans endonuclease IV 0.0161 0.0146 0.0367
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0083
Echinococcus granulosus voltage gated potassium channel 0.0037 0.0012 0.0012
Schistosoma mansoni DNA topoisomerase II 0.0136 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Brugia malayi MAP kinase sur-1 0.0154 0.0138 0.0527
Schistosoma mansoni hypothetical protein 0.084 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0136 0.0118 0.0452
Onchocerca volvulus 0.084 0.0883 0.3631
Echinococcus multilocularis serotonin receptor 0.4105 0.4426 0.4426
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.009 0.0371
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.004 0.0014 0.0058
Trichomonas vaginalis histone deacetylase, putative 0.004 0.0014 0.0058
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0306 0.0303 0.0784
Loa Loa (eye worm) cytochrome P450 family protein 0.0133 0.0115 0.026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0008 0.0023
Echinococcus multilocularis conserved hypothetical protein 0.1419 0.1512 0.1512
Mycobacterium ulcerans aldehyde dehydrogenase 0.0306 0.0303 0.0784
Echinococcus granulosus carbonyl reductase 1 0.0048 0.0024 0.0024
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.006 0.0414
Echinococcus granulosus g protein coupled receptor 0.084 0.0883 0.0883
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.0208
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.009 0.0204
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0018 0.0018
Brugia malayi follicle stimulating hormone receptor 0.2081 0.223 0.8514
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.0063 0.0242
Leishmania major hypothetical protein, conserved 0.0048 0.0024 0.0083
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1985 0.2126 0.4803
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0431 0.0439 0.0439
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus multilocularis mitogen activated protein kinase 11 0.025 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0052 0.0028 0.0063
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.0028 0.0028
Schistosoma mansoni histamine h1 receptor 0.084 0.0883 0.0883
Leishmania major heat shock protein 83-1 0.0136 0.0118 0.0445
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0306 0.0303 0.1152
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.009 0.0217
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0076 0.0054 0.0122
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0098 0.0077 0.0185
Mycobacterium ulcerans short chain dehydrogenase 0.0048 0.0024 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.084 0.0883 0.0883
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0076 0.0054 0.02
Onchocerca volvulus 0.084 0.0883 0.3631
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0059 0.0035 0.0133
Loa Loa (eye worm) hypothetical protein 0.0109 0.009 0.0203
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0048 0.0024 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0003 0.0012
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0035 0.0144
Loa Loa (eye worm) hypothetical protein 0.004 0.0015 0.0033
Mycobacterium tuberculosis Probable two component sensor kinase 0.0136 0.0118 0.0293
Echinococcus granulosus zinc finger protein 0.0058 0.0034 0.0034
Brugia malayi RNA binding protein 0.0066 0.0043 0.0164
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.0028 0.0028
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0014 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0058 0.0034 0.0068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0287 0.0283 0.0283
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0136 0.0118 0.1702
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0003 0.0014
Schistosoma mansoni methyl-cpg binding protein mbd 0.0038 0.0013 0.0013
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0048 0.0024 0.0083
Onchocerca volvulus 0.0032 0.0006 0.001
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Schistosoma mansoni neuropeptide receptor 0.084 0.0883 0.0883
Schistosoma mansoni biogenic amine receptor 0.084 0.0883 0.0883
Loa Loa (eye worm) oxidoreductase 0.0048 0.0024 0.0053
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0058 0.0034 0.0068
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0048 0.0024 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0048 0.0024 0.009
Echinococcus multilocularis g protein coupled receptor 0.084 0.0883 0.0883
Echinococcus multilocularis histone deacetylase 3 0.004 0.0014 0.0014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0053
Loa Loa (eye worm) hypothetical protein 0.0041 0.0016 0.0035
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0018 0.0018
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0008 0.0008
Schistosoma mansoni intermediate filament proteins 0.0085 0.0063 0.0063
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0109 0.0089 0.0368
Echinococcus multilocularis retinol dehydrogenase 11 0.0048 0.0024 0.0024
Echinococcus granulosus biogenic amine 5HT receptor 0.1638 0.1749 0.1749
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0001 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.084 0.0883 0.0883
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0431 0.0439 0.0992
Brugia malayi G protein-coupled receptor F59B2.13 0.084 0.0883 0.337
Echinococcus multilocularis thyroid hormone receptor alpha 0.0052 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0048 0.0024 0.0149
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0058 0.0034 0.0068
Mycobacterium tuberculosis Probable oxidoreductase 0.0248 0.0241 0.0618
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0048 0.0024 0.0225
Loa Loa (eye worm) hypothetical protein 0.0041 0.0016 0.0036
Giardia lamblia Short-chain dehydrogenase, putative 0.0048 0.0024 0.0149
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0076 0.0054 0.0122
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0043 0.0097
Brugia malayi Glycosyl hydrolases family 31 protein 0.0082 0.006 0.0228
Echinococcus multilocularis muscleblind protein 1 0.061 0.0634 0.0634
Schistosoma mansoni histone deacetylase 4 5 0.0038 0.0012 0.0012
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0048 0.0024 0.0024
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0008 0.0023
Mycobacterium ulcerans short-chain type oxidoreductase 0.0048 0.0024 0.0041
Schistosoma mansoni hypothetical protein 0.0054 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.084 0.0883 0.1994
Schistosoma mansoni steroid dehydrogenase 0.0048 0.0024 0.0024
Trypanosoma brucei histone deacetylase 4 0.0038 0.0012 0.0038
Schistosoma mansoni hypothetical protein 0.0347 0.0347 0.0347
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.006 0.0246
Leishmania major cytochrome p450-like protein 0.0058 0.0034 0.0121
Schistosoma mansoni hypothetical protein 0.0058 0.0034 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0048 0.0024 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0367 0.037 0.1412
Loa Loa (eye worm) hypothetical protein 0.0109 0.009 0.0203
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0028 0.0028
Loa Loa (eye worm) glutathione reductase 0.0098 0.0077 0.0175
Giardia lamblia Reductase, putative 0.0048 0.0024 0.0149
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0059 0.0035 0.0133
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0383 0.0387 0.1597

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 40 % Agonist activity in mouse by hot water tail withdrawal assay at 32 mg/kg, sc ChEMBL. 16913723
Activity (functional) > 90 % Antagonist activity against morphin-induced antinociception in sc dosed mouse by hot water tail withdrawal assay at 32 mg/kg, sc ChEMBL. 16913723
IC50 (binding) = 0.87 nM Binding affinity against mu opioid receptor from calf frontal cortex. ChEMBL. 7693944
IC50 (binding) = 12.1 nM Binding affinity against kappa opioid receptor from calf frontal cortex. ChEMBL. 7693944
IC50 (binding) = 21.2 nM Binding affinity against delta opioid receptor from calf frontal cortex. ChEMBL. 7693944

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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