Detailed information for compound 18858

Basic information

Technical information
  • TDR Targets ID: 18858
  • Name: [6-(aziridin-1-yl)-7-methyl-5,8-dioxo-2,3-dih ydro-1H-pyrrolo[1,2-a]benzimidazol-3-yl] prop anoate
  • MW: 315.324 | Formula: C16H17N3O4
  • H donors: 0 H acceptors: 4 LogP: 0.98 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)OC1CCn2c1nc1c2C(=O)C(=C(C1=O)N1CC1)C
  • InChi: 1S/C16H17N3O4/c1-3-10(20)23-9-4-5-19-13-11(17-16(9)19)15(22)12(18-6-7-18)8(2)14(13)21/h9H,3-7H2,1-2H3
  • InChiKey: NPSQJYCWTMTMAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • propanoic acid [6-(1-aziridinyl)-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-3-yl] ester
  • propionic acid (6-ethylenimino-5,8-diketo-7-methyl-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-3-yl) ester
  • 1H-Pyrrolo[1,2-a]benzimidazole-5,8-dione, 6-(1-aziridinyl)- 2,3-dihydro-3-(propionyl)-7-methyl-
  • ANTINEOPLASTIC-651079
  • NSC651079
  • AIDS-044385
  • AIDS044385
  • NCI60_017867

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0012 0.0012
Schistosoma mansoni chromobox protein 0.0012 0.0005 0.0005
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.024 0.0769 0.7487
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0008 0.0094
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.028 0.028
Mycobacterium ulcerans dehydrogenase 0.0012 0.0006 0.002
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0005 0.0005
Echinococcus granulosus pyruvate kinase 0.0018 0.0025 0.0025
Trypanosoma cruzi short chain dehydrogenase, putative 0.0013 0.0008 0.0061
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0014 0.0012 0.0012
Brugia malayi Sugar transporter family protein 0.0011 0.0001 0.0003
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0013 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0332 0.1077 0.2104
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0012 0.0006 0.0012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0114 0.0193
Schistosoma mansoni chromobox protein 0.0012 0.0005 0.0005
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0013 0.0008 0.0061
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0012 0.0003 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.0136 0.0419 0.0819
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Plasmodium vivax ferrodoxin reductase, putative 0.0012 0.0006 0.0071
Mycobacterium ulcerans ferredoxin reductase 0.0012 0.0006 0.002
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0014 0.0012 0.0021
Trypanosoma brucei NADH dehydrogenase 0.0012 0.0006 0.0049
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0097 0.0288 0.0288
Onchocerca volvulus 0.0106 0.032 0.0548
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0031 0.0284
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0032 0.0052
Leishmania major hypothetical protein, conserved 0.0013 0.0008 0.0061
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0097 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0041 0.0388
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0047 0.0122 0.1178
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0062
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0076
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.0467 0.4544
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0065 0.0182 0.6165
Loa Loa (eye worm) RecQ helicase 0.0047 0.0122 0.0239
Echinococcus granulosus dna polymerase eta 0.0074 0.0211 0.0211
Entamoeba histolytica hypothetical protein 0.002 0.0032 0.0059
Plasmodium vivax JmjC domain containing protein 0.0016 0.002 0.0257
Schistosoma mansoni tensin-related 0.0013 0.0007 0.0007
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0006 0.0009
Echinococcus multilocularis chromobox protein 1 0.0012 0.0005 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0075 0.0126
Giardia lamblia NADH oxidase lateral transfer candidate 0.0047 0.0122 0.023
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0013 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Echinococcus granulosus histone lysine N methyltransferase SETD2 0.0011 0.0001 0.0001
Mycobacterium ulcerans oxidoreductase 0.0013 0.0008 0.0025
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0013 0.0008 0.0025
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0114 0.159
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0014 0.0012 0.0041
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0032 0.0032
Echinococcus multilocularis retinol dehydrogenase 13 0.0013 0.0008 0.0008
Brugia malayi CXXC zinc finger family protein 0.0092 0.0274 0.0535
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0038
Echinococcus granulosus solute carrier family 22 0.0011 0.0001 0.0001
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.0008 0.0065
Toxoplasma gondii carbonyl reductase 1, putative 0.0013 0.0008 0.0076
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0008 0.0025
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0098 0.0291 0.0544
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0013 0.0008 0.0011
Leishmania major DNA polymerase kappa, putative 0.0023 0.0041 0.0388
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0061
Echinococcus granulosus Solute carrier family 22 5 0.1162 0.3855 0.3855
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0223 0.071 0.071
Brugia malayi SET domain containing protein 0.0011 0.0001 0.0002
Leishmania major oxidoreductase-like protein 0.0013 0.0008 0.0061
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0342 0.0584
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0012 0.0012
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0012 0.0006 0.001
Mycobacterium ulcerans carveol-like dehydrogenase 0.0013 0.0008 0.0025
Onchocerca volvulus 0.0011 0.0001 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0041 0.0041
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0014 0.0012 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0012 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0342 0.0584
Schistosoma mansoni voltage-gated cation channel 0.0097 0.0288 0.0288
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0171 0.0171
Loa Loa (eye worm) X11 protein 0.0069 0.0196 0.0382
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Brugia malayi SET domain containing protein 0.0015 0.0016 0.0031
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0013 0.0008 0.0015
Schistosoma mansoni SET domain protein 0.0015 0.0016 0.0016
Echinococcus multilocularis L aminoadipate semialdehyde 0.0347 0.1126 0.1126
Giardia lamblia DNA damage repair protein 0.0023 0.0041 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0211 0.0827
Plasmodium vivax importin-beta 2, putative 0.0029 0.0062 0.085
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0013 0.0008 0.0025
Schistosoma mansoni hypothetical protein 0.0359 0.1166 0.1166
Brugia malayi hypothetical protein 0.0128 0.0391 0.0764
Loa Loa (eye worm) RGS-3 protein 0.002 0.0032 0.0062
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0134 0.0414 0.0414
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.003 0.003
Brugia malayi hypothetical protein 0.0011 0.0001 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.008 0.0157
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0012 0.0006 0.002
Mycobacterium ulcerans short-chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus granulosus retinol dehydrogenase 11 0.0013 0.0008 0.0008
Plasmodium falciparum basic transcription factor 3b, putative 0.0113 0.0342 0.8152
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0191 0.0605 0.2374
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0047 0.0122 0.1178
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0182 0.031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0043 0.0072
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0043 0.0408
Loa Loa (eye worm) ICD-1 protein 0.0113 0.0342 0.0668
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Entamoeba histolytica hypothetical protein 0.0012 0.0005 0.0007
Leishmania major short chain dehydrogenase, putative 0.0013 0.0008 0.0061
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0098 0.0291 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0012 0.0003 0.0007
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0013 0.0008 0.0008
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0005 0.0005
Leishmania major short chain dehydrogenase-like protein 0.0013 0.0008 0.0061
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0036 0.0066
Loa Loa (eye worm) hypothetical protein 0.0048 0.0126 0.0247
Loa Loa (eye worm) hypothetical protein 0.0059 0.016 0.0313
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0126 0.0126
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0126 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0012 0.0003 0.0007
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0062
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Loa Loa (eye worm) 6-phosphofructokinase 0.024 0.0769 0.1502
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0013 0.0008 0.0013
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0012 0.0003 0.0007
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0012 0.0012
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0014 0.0012 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0182 0.031
Schistosoma mansoni DNA helicase recq1 0.0019 0.003 0.003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0187 0.059 0.7144
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0047 0.0122 0.0475
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0134 0.0414 0.4021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0036 0.0337
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0032 0.0032
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Echinococcus multilocularis phd:f box containing protein 0.0016 0.002 0.002
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0012 0.0006 0.0049
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0032 0.0032
Echinococcus multilocularis 0.0012 0.0003 0.0003
Trichomonas vaginalis apoptosis inducing factor, putative 0.0012 0.0006 0.0009
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Schistosoma mansoni ap endonuclease 0.002 0.0031 0.0031
Echinococcus granulosus solute carrier family 22 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.031 0.1002 0.3937
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0126 0.0217
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.028 0.028
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0178 0.0562 0.1097
Echinococcus granulosus L aminoadipate semialdehyde 0.0347 0.1126 0.1126
Echinococcus granulosus steroid dehydrogenase 0.0013 0.0008 0.0008
Echinococcus granulosus chromobox protein 2 0.0012 0.0005 0.0005
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0047 0.0122 0.1178
Onchocerca volvulus 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0062
Mycobacterium ulcerans DNA polymerase IV 0.01 0.0299 0.1172
Trypanosoma brucei DNA polymerase eta, putative 0.0074 0.0211 0.2049
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0014 0.0012 0.0103
Brugia malayi Major Facilitator Superfamily protein 0.0011 0.0001 0.0003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0074 0.0211 0.0211
Schistosoma mansoni pyruvate kinase 0.0035 0.0082 0.0082
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0012 0.0003 0.0017
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.006 0.0823
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0008 0.0013
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0014 0.0012 0.0023
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0005 0.0009
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.031 0.1002 0.3937
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus granulosus carbonyl reductase 1 0.0013 0.0008 0.0008
Onchocerca volvulus 0.0011 0.0001 0.0002
Trichomonas vaginalis rotamase, putative 0.0033 0.0075 0.0126
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0012 0.0006 0.0061
Schistosoma mansoni pyruvate kinase 0.0018 0.0025 0.0025
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0049 0.0091
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0012 0.0006 0.0061
Schistosoma mansoni terminal deoxycytidyl transferase 0.0074 0.0211 0.0211
Giardia lamblia Hypothetical protein 0.0013 0.0008 0.0012
Loa Loa (eye worm) sugar transporter 0.0011 0.0001 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0012 0.0006 0.0006
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Trypanosoma cruzi NADH dehydrogenase, putative 0.0012 0.0006 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0355 0.0607
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0102 0.0191
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0134 0.0414 0.0808
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0047 0.0122 0.0475
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0059 0.0161 0.1559
Schistosoma mansoni cpg binding protein 0.0098 0.0291 0.0291
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0047 0.0122 0.0122
Schistosoma mansoni chromobox protein 0.0012 0.0005 0.0005
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0069 0.0069
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0012 0.0006 0.0006
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0014 0.0012 0.0103
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0032 0.0032
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0013 0.0008 0.0008
Echinococcus multilocularis glutamate synthase 0.0012 0.0006 0.0006
Leishmania major short chain dehydrogenase/reductase, putative 0.0013 0.0008 0.0061
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0012 0.0003 0.0007
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0013 0.0008 0.0008
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0082 0.0138
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0082 0.1136
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0014 0.0012 0.0041
Echinococcus multilocularis pyruvate kinase 0.0018 0.0025 0.0025
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0098 0.0291 0.3517
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0012 0.0006 0.001
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0008 0.0094
Giardia lamblia Short-chain dehydrogenase, putative 0.0013 0.0008 0.0012
Mycobacterium ulcerans hypothetical protein 0.0023 0.0041 0.0157
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0032 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0355 0.0607
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0047 0.0122 0.4066
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.077 0.2543 1
Schistosoma mansoni tensin-related 0.0013 0.0007 0.0007
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0031 0.0284
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0126 0.0126
Echinococcus granulosus voltage dependent calcium channel 0.002 0.0032 0.0032
Echinococcus granulosus SHC transforming protein 3 0.0013 0.0007 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0031 0.0115
Schistosoma mansoni glutamate synthase 0.0012 0.0006 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0355 0.0607
Onchocerca volvulus 0.0013 0.0008 0.0013
Trypanosoma cruzi NADH dehydrogenase, putative 0.0012 0.0006 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0355 0.0355
Echinococcus multilocularis chromobox protein 2 0.0012 0.0005 0.0005
Treponema pallidum gamma-glutamyl phosphate reductase 0.0014 0.0012 0.0011
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0013 0.0008 0.0061
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0041 0.0388
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0149 0.0149
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0821 0.2714 0.2714
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0009
Onchocerca volvulus 0.0011 0.0001 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Onchocerca volvulus Putative transporter 0.0011 0.0001 0.0002
Onchocerca volvulus 0.0013 0.0008 0.0013
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0008 0.0025
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Echinococcus multilocularis mitogen activated protein kinase 0.0117 0.0355 0.0355
Onchocerca volvulus 0.0048 0.0126 0.0217
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0473 0.0473
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.007 0.0136
Trypanosoma brucei oxidoreductase-like protein 0.0013 0.0008 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0014 0.0012 0.0041
Schistosoma mansoni ran 0.0021 0.0036 0.0036
Leishmania major DNA polymerase eta, putative 0.0023 0.0041 0.0388
Leishmania major hypothetical protein, conserved 0.0028 0.006 0.0568
Onchocerca volvulus 0.0106 0.032 0.0548
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0075 0.0126
Brugia malayi Pre-SET motif family protein 0.0223 0.071 0.1386
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0031 0.0704
Loa Loa (eye worm) voltage-dependent calcium channel 0.002 0.0032 0.0063
Onchocerca volvulus 0.0011 0.0001 0.0002
Echinococcus granulosus transcription factor btf3 0.0113 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0041 0.0483
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0075 0.0126
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0012 0.0006 0.002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0041 0.0483
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Brugia malayi intermediate filament protein 0.0059 0.016 0.0313
Leishmania major basic transcription factor 3a, putative 0.0113 0.0342 0.3322
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Brugia malayi RNA, U transporter 1 0.0082 0.024 0.047
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0014 0.0012 0.0041
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0014 0.0012 0.0041
Echinococcus granulosus phd:f box containing protein 0.0016 0.002 0.002
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0014 0.0012 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0068 0.0262
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0035 0.0035
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0012 0.0006 0.002
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0097 0.0288 0.0288
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0008 0.0013
Schistosoma mansoni DNA polymerase eta 0.0074 0.0211 0.0211
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0013 0.0008 0.0081
Leishmania major hypothetical protein, conserved 0.0013 0.0008 0.0061
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.006 0.0568
Brugia malayi Retinol dehydrogenase 12 0.0013 0.0008 0.0015
Echinococcus granulosus expressed protein 0.0033 0.0075 0.0075
Echinococcus granulosus importin subunit beta 1 0.0029 0.0062 0.0062
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0082 0.0977
Trichomonas vaginalis phosphofructokinase, putative 0.024 0.0769 0.1317
Entamoeba histolytica phosphofructokinase, putative 0.024 0.0769 0.1465
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0012 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0023
Giardia lamblia Glutamate synthase 0.0012 0.0006 0.001
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Echinococcus granulosus CTD small phosphatase protein like 0.0013 0.0008 0.0008
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0013 0.0008 0.0013
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0013 0.0008 0.0061
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0347 0.1126 0.1126
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0097 0.0288 0.0288
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0012 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Trypanosoma brucei unspecified product 0.0093 0.0277 0.2692
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.003 0.0058
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0036 0.007
Echinococcus granulosus WW domain containing oxidoreductase 0.0013 0.0008 0.0008
Brugia malayi hypothetical protein 0.0018 0.0026 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0075 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0012 0.0003 0.0007
Echinococcus granulosus thioredoxin glutathione reductase 0.0136 0.0421 0.0421
Echinococcus multilocularis pyruvate kinase 0.0035 0.0082 0.0082
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0182 0.031
Onchocerca volvulus 0.0015 0.0016 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Entamoeba histolytica hypothetical protein 0.002 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Entamoeba histolytica hypothetical protein 0.0113 0.0342 0.065
Trichomonas vaginalis phosphofructokinase, putative 0.024 0.0769 0.1317
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0014 0.0012 0.0012
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0007 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0182 0.031
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0102 0.0192
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0012 0.0003 0.0007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0005 0.0005
Toxoplasma gondii aldehyde dehydrogenase 0.0257 0.0825 1
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0014 0.0012 0.0018
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0031 0.0031
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0013 0.0008 0.0076
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0032 0.0032
Leishmania major GTP-binding protein, putative 0.0021 0.0036 0.0337
Echinococcus multilocularis conserved hypothetical protein 0.0013 0.0008 0.0008
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0013 0.0008 0.0008
Schistosoma mansoni transcription factor btf3 0.0113 0.0342 0.0342
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0117 0.0355 0.0694
Loa Loa (eye worm) major facilitator superfamily transporter 0.0011 0.0001 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.0122 0.1178
Entamoeba histolytica phosphofructokinase, putative 0.024 0.0769 0.1465
Trypanosoma cruzi short chain dehydrogenase, putative 0.0013 0.0008 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0032
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.016 0.0313
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0037 0.0061
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.008 0.0233 0.2261
Trypanosoma brucei protein kinase, putative 0.0117 0.0355 0.3451
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0309 0.1 0.1
Schistosoma mansoni ap endonuclease 0.002 0.0031 0.0031
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0013 0.0008 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0204 0.0648 0.0648
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0012 0.0003 0.0007
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0013 0.0008 0.0076
Schistosoma mansoni glucose transport protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0032 0.0062
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0012 0.0006 0.0049
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0036 0.042
Plasmodium falciparum glutathione reductase 0.0136 0.0419 1
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0014 0.0012 0.0041
Echinococcus multilocularis carbonyl reductase 1 0.0013 0.0008 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.007 0.0137
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0013 0.0008 0.0013
Plasmodium falciparum glutathione reductase 0.0047 0.0122 0.2895
Entamoeba histolytica hypothetical protein 0.002 0.0032 0.0059
Brugia malayi oxidoreductase 0.0013 0.0008 0.0015
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0473 0.0473
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0032 0.0032
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.002 0.002
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0012 0.0006 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0068 0.0133
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0082 0.014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0075 0.0126
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0032 0.0032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Onchocerca volvulus 0.0013 0.0008 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0092 0.0274 0.0535
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0036 0.0036
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.008 0.0233 0.0912
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0005 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0075 0.0126
Loa Loa (eye worm) glutathione reductase 0.0136 0.0419 0.0819
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0035 0.0035
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0036 0.0337
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0068 0.065
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Echinococcus multilocularis expressed protein 0.0391 0.1273 0.1273
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0097 0.0288 0.0288
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0013 0.0008 0.0008
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0149 0.0149
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0012 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0058
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0022 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0047
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0012 0.0006 0.0128
Echinococcus multilocularis synaptic vesicle 2 protein 0.0011 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0012 0.0003 0.0007
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0013 0.0008 0.0013
Trichomonas vaginalis glutathione reductase, putative 0.0047 0.0122 0.0207
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0031 0.0056
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0082 0.0785
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0006 0.0009
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0065 0.0182 0.031
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0012 0.0006 0.0049
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0014 0.0012 0.0041
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0012 0.0003 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0041 0.0388
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0014 0.0012 0.0023
Mycobacterium ulcerans ketoacyl reductase 0.0013 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0091 0.0177
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0012 0.0006 0.0013
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0005 0.0007
Onchocerca volvulus 0.0013 0.0008 0.0013
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0012 0.0006 0.0006
Brugia malayi hypothetical protein 0.0106 0.032 0.0624
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0149 0.0149
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0134 0.0414 0.0787
Mycobacterium ulcerans oxidoreductase 0.0013 0.0008 0.0025
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0013 0.0008 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans hypothetical protein 0.0167 0.0524 0.2056
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0082 0.0785
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0005 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0014 0.0012 0.0012
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0013 0.0008 0.0018
Brugia malayi PXA domain containing protein 0.002 0.0032 0.0062
Plasmodium falciparum thioredoxin reductase 0.0047 0.0122 0.2895
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0005 0.0005
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0014 0.0012 0.0012
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0065 0.0182 0.0344
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0047 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0047
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0041 0.0562
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0082 0.014
Loa Loa (eye worm) intermediate filament protein 0.0059 0.016 0.0313
Trypanosoma brucei unspecified product 0.0051 0.0135 0.1302
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0074 0.0211 0.0413
Echinococcus granulosus histone lysine methyltransferase setb 0.0223 0.071 0.071
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0114 0.1367
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0117 0.0355 0.3451
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0609 0.2003 0.3434
Giardia lamblia Thioredoxin reductase 0.0012 0.0006 0.001
Echinococcus granulosus cytochrome P450 2K1 0.0012 0.0003 0.0003
Brugia malayi Sugar transporter family protein 0.0011 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0042 0.007
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0013 0.0008 0.0025
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0012 0.0006 0.0061
Schistosoma mansoni amyloid beta A4 protein related 0.0069 0.0196 0.0196
Schistosoma mansoni shc transforming protein 0.0013 0.0007 0.0007
Mycobacterium ulcerans dehydrogenase/reductase 0.0013 0.0008 0.0025
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.002 0.0221
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0012 0.0006 0.0071
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0023
Entamoeba histolytica hypothetical protein 0.0024 0.0043 0.008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0005 0.0007
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0005 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0047 0.0122 0.0475
Loa Loa (eye worm) MBCTL1 0.0055 0.0149 0.029
Trichomonas vaginalis hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0012 0.0005 0.0005
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0082 0.0785
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0072 0.069
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0097 0.0288 0.0288
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0014 0.0012 0.0041
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Treponema pallidum fructose-bisphosphate aldolase 0.1577 0.5243 1
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0013 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0009
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0012 0.0003 0.0007
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0032 0.0032
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0049
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0014 0.0012 0.0012
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0014 0.0012 0.0041
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0071 0.0988
Echinococcus granulosus pyruvate kinase 0.0018 0.0025 0.0025
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0032 0.0032
Trypanosoma brucei trypanothione reductase 0.0136 0.0419 0.4076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0075 0.0126
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0059 0.0059
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0114 0.1098
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0012 0.0006 0.0009
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0012 0.0003 0.0007
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0005 0.0005
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0008 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0075 0.0146
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0134 0.0414 0.0808
Echinococcus multilocularis expressed protein 0.0033 0.0075 0.0075
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0124 0.038 0.0743
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0068 0.065
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0031 0.0411
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0157 0.1514
Mycobacterium ulcerans aldehyde dehydrogenase 0.0257 0.0825 0.3241
Leishmania major hypothetical protein, conserved 0.0016 0.002 0.0177
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Echinococcus multilocularis Chromo domain 0.0012 0.0005 0.0005
Schistosoma mansoni lamin 0.0059 0.016 0.016
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0171 0.0171
Echinococcus multilocularis voltage dependent calcium channel 0.0097 0.0288 0.0288
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.077 0.2543 1
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0014 0.0012 0.0103
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0008 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0257 0.0825 0.3241
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0014 0.0012 0.0041
Trypanosoma cruzi transcription factor btf3, putative 0.0113 0.0342 0.3322
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0157 0.1514
Mycobacterium ulcerans dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0012 0.0003 0.0007
Echinococcus granulosus Chromobox protein 3 0.0012 0.0005 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.003 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus multilocularis carbonyl reductase 1 0.0013 0.0008 0.0008
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0122 0.0208
Schistosoma mansoni axis inhibition protein axin 0.002 0.0032 0.0032
Entamoeba histolytica deoxycytidyl transferase, putative 0.0074 0.0211 0.0401
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0191 0.0605 0.5885
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0098 0.0291 0.114
Brugia malayi Dehydrogenases, short chain protein 2 0.0013 0.0008 0.0015
Giardia lamblia Kinase, CMGC MAPK 0.0117 0.0355 0.0675
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.003 0.0058
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0012 0.0006 0.0012
Toxoplasma gondii oxidoreductase, putative 0.0013 0.0008 0.0076
Trichomonas vaginalis DNA polymerase eta, putative 0.01 0.0299 0.0511
Onchocerca volvulus 0.0013 0.0008 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0013 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.0524 0.2056
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0036 0.0036
Echinococcus multilocularis amyloid beta A4 protein 0.0069 0.0196 0.0196
Brugia malayi dehydrogenases, short chain protein 9 0.0013 0.0008 0.0015
Echinococcus granulosus axis inhibition protein axin 0.002 0.0032 0.0032
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0013 0.0007 0.0007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0223 0.071 0.8598
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0035 0.0035
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0097 0.0288 0.0288
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0031 0.0115
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.024 0.0769 0.7487
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.0045
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0124 0.038 0.038
Schistosoma mansoni sugar transporter 0.0011 0.0001 0.0001
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0124 0.038 0.038
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0087 0.0087
Trichomonas vaginalis rotamase, putative 0.0032 0.0072 0.0121
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0117 0.0355 0.3451
Echinococcus multilocularis retinol dehydrogenase 11 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Onchocerca volvulus Sepiapterin reductase homolog 0.0013 0.0008 0.0013
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0012 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0009
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0012 0.0006 0.0049
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0008 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.002 0.002
Echinococcus multilocularis dna polymerase eta 0.0074 0.0211 0.0211
Echinococcus multilocularis thioredoxin glutathione reductase 0.0136 0.0421 0.0421
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0012 0.0006 0.001
Onchocerca volvulus 0.0011 0.0001 0.0002
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0032 0.0032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Trichomonas vaginalis hypothetical protein 0.0011 0.0002 0.0001
Echinococcus granulosus carbonyl reductase 1 0.0013 0.0008 0.0008
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0114 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Schistosoma mansoni hypothetical protein 0.0013 0.0008 0.0008
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0014 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0013 0.0008 0.0013
Schistosoma mansoni 6-phosphofructokinase 0.024 0.0769 0.0769
Trichomonas vaginalis phosphofructokinase, putative 0.024 0.0769 0.1317
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0014 0.0012 0.0021
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Echinococcus granulosus axis inhibition protein axin 0.002 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0028 0.0059 0.0115
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.0605 0.0605
Leishmania major DNA polymerase kappa, putative 0.008 0.0233 0.2261
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.002 0.002
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0013 0.0008 0.0008
Echinococcus multilocularis dna polymerase kappa 0.01 0.0299 0.0299
Leishmania major DNA polymerase eta, putative 0.0074 0.0211 0.2049
Echinococcus multilocularis steroid dehydrogenase 0.0013 0.0008 0.0008
Brugia malayi polk-prov protein 0.0049 0.0129 0.0252
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0223 0.071 0.071
Loa Loa (eye worm) hypothetical protein 0.0347 0.1126 0.2199
Onchocerca volvulus 0.0012 0.0006 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.006 0.0707
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0117 0.0355 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0257 0.0825 0.3241
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0012 0.0006 0.0128
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0012 0.0012
Leishmania major mitochondrial DNA polymerase beta 0.0317 0.1027 1
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0008 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0012 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0062 0.012
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.002 0.002
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0013 0.0008 0.0061
Brugia malayi POT family protein 0.0092 0.0271 0.053
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0014 0.0012 0.0041
Onchocerca volvulus 0.0013 0.0008 0.0013
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0098 0.0291 1
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0609 0.2003 0.382
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0012 0.0006 0.0012
Schistosoma mansoni hypothetical protein 0.0054 0.0146 0.0146
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.003 0.0687
Trypanosoma brucei unspecified product 0.0051 0.0135 0.1302
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Toxoplasma gondii thioredoxin reductase 0.0136 0.0419 0.5073
Echinococcus granulosus chromobox protein 1 0.0012 0.0005 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.002 0.0038
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Loa Loa (eye worm) aldehyde dehydrogenase 0.0014 0.0012 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0012 0.0003 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Leishmania major hypothetical protein, conserved 0.0013 0.0008 0.0061
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0012 0.0006 0.0006
Onchocerca volvulus 0.0013 0.0008 0.0013
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0032 0.0032
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0013 0.0008 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0014 0.0012 0.0041
Mycobacterium leprae Probable oxidoreductase 0.0013 0.0008 0.0018
Giardia lamblia Fructose-bisphosphate aldolase 0.1577 0.5243 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0031 0.006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0188 0.0188
Echinococcus multilocularis solute carrier family 22 0.0011 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0006 0.0049
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0014 0.0012 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0062 0.0587
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0032 0.0062
Echinococcus multilocularis solute carrier family 22 0.0011 0.0001 0.0001
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0072 0.069
Leishmania major aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Entamoeba histolytica transcription factor BTF3, putative 0.0113 0.0342 0.065
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0043 0.0072
Leishmania major short chain dehydrogenase, putative 0.0013 0.0008 0.0061
Echinococcus granulosus oxidoreductase 0.0013 0.0008 0.0008
Leishmania major aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0012 0.0003 0.0007
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0014 0.0012 0.0012
Leishmania major importin beta-1 subunit, putative 0.0024 0.0043 0.0408
Toxoplasma gondii hypothetical protein 0.0051 0.0136 0.1633
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0012 0.0006 0.0071
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0013 0.0008 0.0168
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0013
Loa Loa (eye worm) POT family protein 0.0092 0.0271 0.053
Loa Loa (eye worm) major facilitator superfamily transporter 0.0011 0.0001 0.0003
Brugia malayi jmjC domain containing protein 0.0062 0.0171 0.0334
Echinococcus granulosus intermediate filament protein 0.0059 0.016 0.016
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.0605 0.0605
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Plasmodium falciparum hexose transporter 0.0011 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0223 0.071 0.1386
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.002 0.002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0065 0.0182 0.0335
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0344 0.1118 0.4392
Schistosoma mansoni hypothetical protein 0.0359 0.1166 0.1166
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Chlamydia trachomatis pyruvate kinase 0.0035 0.0082 0.2652
Trypanosoma brucei DNA polymerase IV, putative 0.01 0.0299 0.2904
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0082 0.016
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0031 0.0046
Mycobacterium ulcerans ketoacyl reductase 0.0013 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0055 0.0149 0.029
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0061
Brugia malayi mbt repeat family protein 0.0048 0.0126 0.0247
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0013 0.0008 0.0025
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0014 0.0012 0.0041
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.007 0.0834
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0012 0.0003 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.002 0.0038
Mycobacterium tuberculosis Possible oxidoreductase 0.0013 0.0008 0.0025
Trypanosoma brucei DNA polymerase IV, putative 0.0093 0.0277 0.2692
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0008 0.0008
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0013 0.0008 0.0008
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.031 0.1002 0.3937
Loa Loa (eye worm) hypothetical protein 0.0057 0.0157 0.0306
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0122 0.0239
Schistosoma mansoni chromobox protein 0.0012 0.0005 0.0005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0257 0.0825 0.0825
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0032 0.0062
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0032 0.0062
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0012 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0012 0.0006 0.002
Echinococcus granulosus synaptic vesicle 2 protein 0.0011 0.0001 0.0001
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0014 0.0012 0.0103
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0012 0.0003 0.0007
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0012 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Brugia malayi MAP kinase sur-1 0.0117 0.0355 0.0694
Echinococcus granulosus lamin dm0 0.0059 0.016 0.016
Brugia malayi ImpB/MucB/SamB family protein 0.0074 0.0211 0.0413
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0012 0.0005 0.0008
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0012 0.0006 0.002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.0122 0.4168
Loa Loa (eye worm) calcium channel 0.0097 0.0288 0.0562
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0223 0.071 0.071
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.154 0.5119 1
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0317 0.1027 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0012 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0012 0.0003 0.0017
Onchocerca volvulus 0.0235 0.075 0.1286
Schistosoma mansoni sugar transporter 0.0011 0.0001 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.006 0.0568
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0076
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0157 0.1514
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0171 0.0171
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0013 0.0008 0.0013
Echinococcus multilocularis transcription factor Dp 1 0.0078 0.0225 0.0225
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0012 0.0003 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0098 0.0291 0.0553
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0082 0.0317
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0134 0.0414 0.4021
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.002 0.0443
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0098 0.0291 0.3517
Brugia malayi Aldehyde dehydrogenase protein 4 0.0014 0.0012 0.0023
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0031 0.005
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0013 0.0008 0.0025
Giardia lamblia Reductase, putative 0.0013 0.0008 0.0012
Brugia malayi CHD4 protein 0.0017 0.0022 0.0043
Schistosoma mansoni hypothetical protein 0.0428 0.1399 0.1399
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0013 0.0008 0.0025
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0114 0.1367
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0012 0.0006 0.001
Loa Loa (eye worm) glutaminase 0.0286 0.0923 0.1803
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0114 0.1098
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0117
Schistosoma mansoni sugar transporter 0.0011 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Plasmodium falciparum thioredoxin reductase 0.0136 0.0419 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Brugia malayi Cytochrome P450 family protein 0.0031 0.0068 0.0133
Trypanosoma cruzi trypanothione reductase, putative 0.0136 0.0419 0.4076
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0188 0.0188
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.031 0.1002 0.3932
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0097 0.0288 0.0288
Schistosoma mansoni protein phosphatase 2C 0.0016 0.002 0.002
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0047 0.0122 0.2895
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0012 0.0003 0.0007
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0013 0.0008 0.0061
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0031 0.1005
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0103 0.2445
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0012 0.0003 0.0007
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0012 0.0006 0.0061
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0012 0.0006 0.002
Trichomonas vaginalis helicase, putative 0.0021 0.0035 0.0057
Brugia malayi glutamate synthase 0.0012 0.0006 0.0012
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0013 0.0008 0.0025
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0012 0.0006 0.001
Echinococcus multilocularis musashi 0.0059 0.016 0.016
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0257 0.0825 0.3241
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0065
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0011 0.0001 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Plasmodium vivax glutathione reductase, putative 0.0136 0.0419 0.59
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0047 0.0122 0.0475
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0012 0.0103
Brugia malayi Heterochromatin protein 1 0.0012 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0012 0.0005 0.0007
Giardia lamblia Alcohol dehydrogenase 0.0014 0.0012 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0068 0.0133
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0012 0.0006 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0041 0.0388
Schistosoma mansoni intermediate filament proteins 0.0059 0.016 0.016
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0014 0.0012 0.0103
Schistosoma mansoni lamin 0.0059 0.016 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0147 0.1416
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Onchocerca volvulus 0.0013 0.0008 0.0013
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0049 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0012 0.0003 0.0007
Mycobacterium ulcerans glutamate synthase subunit beta 0.0012 0.0006 0.002
Schistosoma mansoni disulfide oxidoreductase 0.0012 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0061
Brugia malayi hypothetical protein 0.0028 0.006 0.0117
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0016
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Brugia malayi Sugar transporter family protein 0.0011 0.0001 0.0003
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0013 0.0008 0.0008
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0006 0.0009
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0012 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0134 0.0414 0.4021
Toxoplasma gondii exonuclease III APE 0.002 0.0031 0.0353
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0012 0.0006 0.0173
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0013 0.0008 0.0061
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0072 0.069
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0108
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0136 0.0419 0.1644
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0014 0.0012 0.0034
Echinococcus multilocularis sodium channel protein 0.0041 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0057
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0134 0.0414 0.4021
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0117 0.0355 0.4296
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0012 0.0006 0.0006
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0013 0.0008 0.0008
Brugia malayi mbt repeat family protein 0.0048 0.0126 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0012 0.0003 0.0007
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0012 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Brugia malayi chromobox protein homolog 3 0.0012 0.0005 0.0009
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0059 0.0161 0.1559
Onchocerca volvulus 0.0011 0.0001 0.0002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0047 0.0122 0.1466
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0006 0.0049
Loa Loa (eye worm) hypothetical protein 0.0097 0.0288 0.0562
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0062 0.0171 0.0335
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0059 0.0059
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0117 0.0355 0.3451
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0076
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0047 0.0122 0.0239
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0065 0.0182 0.0345
Loa Loa (eye worm) hypothetical protein 0.0024 0.0046 0.0091
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0012 0.0006 0.0049
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0074 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0012
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0013 0.0008 0.0013
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0035 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0006 0.0009
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Schistosoma mansoni jumonji domain containing protein 0.0016 0.002 0.002
Leishmania major aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Trichomonas vaginalis ran, putative 0.0021 0.0036 0.0059
Schistosoma mansoni axis inhibition protein axin 0.002 0.0032 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.003 0.0058
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0188 0.0368
Toxoplasma gondii NADPH-glutathione reductase 0.0047 0.0122 0.1466
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0035 0.0035
Echinococcus granulosus Sugar transporter ERD6 protein 0.0011 0.0001 0.0001
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0014 0.0012 0.0041
Mycobacterium ulcerans short-chain type oxidoreductase 0.0013 0.0008 0.0025
Echinococcus multilocularis solute carrier family 22 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0011 0.0001 0.0002
Echinococcus granulosus retinol dehydrogenase 11 0.0013 0.0008 0.0008
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0005 0.0045
Trypanosoma cruzi transcription factor btf3, putative 0.0113 0.0342 0.3322
Loa Loa (eye worm) 6-phosphofructokinase 0.024 0.0769 0.1502
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0047 0.0122 0.1705
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0032 0.0032
Brugia malayi hypothetical protein 0.002 0.0032 0.0062
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0014 0.0012 0.0041
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0012 0.0006 0.0049
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.0122 0.1178
Giardia lamblia DINP protein human, muc B family 0.008 0.0233 0.0442
Schistosoma mansoni importin beta-1 0.0029 0.0062 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0124 0.038 0.038
Leishmania major DNA damage repair protein, putative 0.0023 0.0041 0.0388
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Mycobacterium tuberculosis Probable dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0013 0.0008 0.0025
Echinococcus granulosus expressed protein 0.0391 0.1273 0.1273
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0012 0.0103
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0257 0.0825 0.0825
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0347 0.1126 0.2199
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.0605 0.2374
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0013 0.0008 0.0013
Echinococcus multilocularis pyruvate kinase 0.0018 0.0025 0.0025
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0082 0.016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0038
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0008 0.0011
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0194 0.0615 0.0615
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0299 0.2904
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0049 0.0464
Entamoeba histolytica hypothetical protein 0.0012 0.0005 0.0007
Echinococcus multilocularis 6 phosphofructokinase 0.024 0.0769 0.0769
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0126 0.0126
Trypanosoma cruzi DNA polymerase eta, putative 0.0074 0.0211 0.2049
Brugia malayi 6-phosphofructokinase 0.024 0.0769 0.1502
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Schistosoma mansoni cpg binding protein 0.0098 0.0291 0.0291
Onchocerca volvulus 0.0011 0.0001 0.0002
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0005 0.0007
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0089 0.0089
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0065 0.0182 0.2191
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0012 0.0003 0.0007
Brugia malayi Cytochrome P450 family protein 0.0012 0.0003 0.0006
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0014 0.0012 0.0012
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0014 0.0012 0.0103
Leishmania major short chain dehydrogenase/reductase, putative 0.0013 0.0008 0.0061
Toxoplasma gondii transporter, cation channel family protein 0.002 0.0032 0.0375
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0014 0.0012 0.0128
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0149 0.029
Leishmania major 3-keto-dihydrosphingosine reductase 0.0013 0.0008 0.0061
Leishmania major pteridine reductase 1 0.0013 0.0008 0.0061
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Echinococcus granulosus voltage dependent calcium channel 0.0097 0.0288 0.0288
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0013 0.0008 0.0008
Echinococcus multilocularis carbonyl reductase 1 0.0013 0.0008 0.0008
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0012 0.0006 0.0013
Plasmodium vivax 6-phosphofructokinase, putative 0.0065 0.0182 0.2549
Toxoplasma gondii NAC domain-containing protein 0.0113 0.0342 0.4135
Mycobacterium leprae conserved hypothetical protein 0.0098 0.0291 0.1134
Treponema pallidum NADH oxidase 0.0047 0.0122 0.0221
Toxoplasma gondii hypothetical protein 0.0018 0.0024 0.0276
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0082 0.016
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0041 0.0388
Brugia malayi major facilitator superfamily protein 0.0011 0.0001 0.0003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0047 0.0122 0.0122
Onchocerca volvulus 0.0011 0.0001 0.0002
Brugia malayi Cytochrome P450 family protein 0.0032 0.007 0.0137
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0012 0.0006 0.0049
Brugia malayi hypothetical protein 0.0011 0.0001 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0014 0.0012 0.0041
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0117 0.0355 0.3451
Brugia malayi hypothetical protein 0.0011 0.0001 0.0003
Schistosoma mansoni carbonyl reductase 0.0013 0.0008 0.0008
Mycobacterium ulcerans DNA polymerase IV 0.01 0.0299 0.1172
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Leishmania major pyruvate kinase 0.0035 0.0082 0.0785
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0014 0.0012 0.0012
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0025 0.0284
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0041 0.0388
Schistosoma mansoni myst-related protein 0.0011 0.0001 0.0001
Leishmania major pyruvate kinase 0.0035 0.0082 0.0785
Leishmania major trypanothione reductase 0.0136 0.0419 0.4076
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0257 0.0825 0.8035
Schistosoma mansoni glucose transport protein 0.0011 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.024 0.0769 0.1317
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0106 0.032 0.0624
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0098 0.0291 0.409
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0098 0.0291 0.6935
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0182 0.031
Onchocerca volvulus 0.0013 0.0008 0.0013
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0013 0.0008 0.0076
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0012 0.0103
Plasmodium vivax steroid dehydrogenase, putative 0.0013 0.0008 0.0089
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.008 0.0157
Onchocerca volvulus 0.0059 0.016 0.0275
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0117 0.0355 0.3451
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0069 0.0069
Plasmodium vivax basic transcription factor 3b, putative 0.0113 0.0342 0.4809
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0082 0.014
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0122 0.0122
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0117 0.0355 0.3451
Loa Loa (eye worm) phosphofructokinase 0.024 0.0769 0.1502
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0013 0.0008 0.0061
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0005 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0012 0.0006 0.002
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0013 0.0008 0.0011
Loa Loa (eye worm) cytochrome P450 0.0012 0.0003 0.0006
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0126 0.0126
Plasmodium vivax 6-phosphofructokinase, putative 0.0065 0.0182 0.2549
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0032 0.0062
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0061
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0149 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0075 0.0126
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0041 0.0102 0.0102
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0011 0.0001 0.0001
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0134 0.0414 0.0414
Trypanosoma brucei DNA polymerase IV, putative 0.01 0.0299 0.2904
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0041 0.0388
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.1027 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.0605 0.2374
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0014 0.0012 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.0045
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0012 0.0006 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.0122 0.1178
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.003 0.0344
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Giardia lamblia Pyruvate kinase 0.0018 0.0025 0.0045
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0097 0.0288 0.0288
Loa Loa (eye worm) acetyltransferase 0.0152 0.0473 0.0923
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0011 0.0001 0.0008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0035 0.0082 0.016
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0098 0.0291 0.114
Brugia malayi Major Facilitator Superfamily protein 0.0011 0.0001 0.0003
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0098 0.0291 0.114
Toxoplasma gondii cytochrome p450 superfamily protein 0.0012 0.0003 0.0022
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Giardia lamblia Pyruvate kinase 0.0035 0.0082 0.0154
Brugia malayi hypothetical protein 0.0066 0.0187 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Mycobacterium ulcerans short-chain dehydrogenase 0.0013 0.0008 0.0025
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0008 0.0008
Plasmodium vivax SET domain protein, putative 0.0223 0.071 1
Brugia malayi cytochrome P450 0.0012 0.0003 0.0006
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0065 0.0182 0.6165
Schistosoma mansoni 6-phosphofructokinase 0.024 0.0769 0.0769
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0344 0.1118 0.4388
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0032 0.0032
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0032 0.0062
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0014 0.0012 0.0023
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0114 0.1098
Echinococcus granulosus glutamate synthase 0.0012 0.0006 0.0006
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0467 0.4544
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Echinococcus multilocularis tensin 0.0013 0.0007 0.0007
Schistosoma mansoni rotamase 0.0033 0.0075 0.0075
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0014 0.0012 0.0041
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0086 0.0168
Schistosoma mansoni cytochrome P450 0.0012 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0008 0.0013
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.0013 0.0008 0.0061
Echinococcus granulosus bloom syndrome protein 0.0047 0.0122 0.0122
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0047 0.0122 0.1178
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0042 0.007
Loa Loa (eye worm) hypothetical protein 0.0066 0.0187 0.0365
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0038
Echinococcus granulosus lamin 0.0059 0.016 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0074 0.0211 0.0413
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0012 0.0003 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0008 0.0089
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0299 0.2904
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0012 0.0003 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.1027 1
Schistosoma mansoni cpg binding protein 0.0092 0.0274 0.0274
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0012 0.0006 0.001
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0014 0.0012 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Echinococcus multilocularis snurportin 1 0.0309 0.1 0.1
Echinococcus granulosus geminin 0.0359 0.1166 0.1166
Trichomonas vaginalis set domain proteins, putative 0.1752 0.5831 1
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0342 0.0584
Trichomonas vaginalis glutamate synthase, putative 0.0012 0.0006 0.0009
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0041 0.0041
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.003 0.0344
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0047 0.0122 0.1705
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0013 0.0008 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Echinococcus multilocularis SHC transforming protein 3 0.0013 0.0007 0.0007
Loa Loa (eye worm) glutaminase 2 0.0286 0.0923 0.1803
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0252
Plasmodium falciparum pyruvate kinase 0.0035 0.0082 0.1933
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0087 0.0171
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0087 0.0087
Schistosoma mansoni phd/f-box containing protein 0.0016 0.002 0.002
Trichomonas vaginalis dullard protein, putative 0.0013 0.0008 0.0011
Echinococcus granulosus carbonyl reductase 1 0.0013 0.0008 0.0008
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0012 0.0006 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0076
Echinococcus granulosus chromobox protein 1 0.0012 0.0005 0.0005
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0075 0.0146
Echinococcus granulosus transcription factor Dp 1 0.0078 0.0225 0.0225
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0014 0.0012 0.0103
Mycobacterium ulcerans ketoacyl reductase 0.0013 0.0008 0.0025
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0008 0.0011
Plasmodium falciparum ferrodoxin reductase-like protein 0.0012 0.0006 0.0128
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0013 0.0008 0.0061
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.002 0.0177
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0014 0.0012 0.0021
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0068 0.0133
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0299 0.2904
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.0063 0.0747
Echinococcus multilocularis retinol dehydrogenase 11 0.0013 0.0008 0.0008
Toxoplasma gondii 6-phosphofructokinase 0.0065 0.0182 0.2191
Brugia malayi Importin beta-1 subunit 0.0029 0.0062 0.012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1577 0.5243 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0052
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0036 0.0835
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0018
Echinococcus granulosus Chromo domain 0.0012 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0117 0.0355 0.0355
Mycobacterium tuberculosis Probable reductase 0.031 0.1002 0.3937
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0006 0.0009
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0149 0.0149
Entamoeba histolytica short chain dehydrogenase family protein 0.0013 0.0008 0.0013
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0022 0.0022
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0008 0.0025
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0037 0.0037
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0031 0.005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0235 0.075 0.075
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0082 0.016
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0014 0.0012 0.0041
Echinococcus granulosus amyloid beta A4 protein 0.0069 0.0196 0.0196
Echinococcus granulosus carbonyl reductase 1 0.0013 0.0008 0.0008
Brugia malayi hypothetical protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0082 0.016
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0049 0.0464
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0003
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Schistosoma mansoni hypothetical protein 0.0298 0.0961 0.0961
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0124 0.038 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0052
Entamoeba histolytica disulphide oxidoreductase, putative 0.0012 0.0006 0.001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0031 0.0284
Entamoeba histolytica thioredoxin reductase, putative 0.0012 0.0006 0.001
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0013 0.0008 0.0025
Onchocerca volvulus 0.0011 0.0001 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0022 0.0022
Echinococcus multilocularis transcription factor btf3 0.0113 0.0342 0.0342
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Echinococcus granulosus dnaJ subfamily B 0.0428 0.1399 0.1399
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0012 0.0003 0.0007
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0014 0.0012 0.0364
Schistosoma mansoni aldehyde dehydrogenase 0.0257 0.0825 0.0825
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0062
Trichomonas vaginalis steroid dehydrogenase, putative 0.0013 0.0008 0.0011
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0008 0.0011
Brugia malayi Protein cec-1. 0.0012 0.0005 0.0009
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0014 0.0012 0.0012
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0005 0.0084
Schistosoma mansoni hypothetical protein 0.0014 0.0012 0.0012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.0122 0.1178
Leishmania major hypothetical protein, conserved 0.0013 0.0008 0.0065
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0049 0.0464
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0012 0.0003 0.0007
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0006 0.0009
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0022 0.0022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.031 0.1002 0.3937
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0012 0.0006 0.0173
Schistosoma mansoni sulfide quinone reductase 0.0012 0.0006 0.0006
Entamoeba histolytica Ran family GTPase 0.0021 0.0036 0.0067
Echinococcus multilocularis pyruvate kinase 0.0028 0.0057 0.0057
Onchocerca volvulus 0.0013 0.0008 0.0013
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0082 0.0785
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0013 0.0008 0.0015
Brugia malayi beta-NAC-like protein 0.0113 0.0342 0.0668
Onchocerca volvulus 0.0011 0.0001 0.0002
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0012 0.0006 0.0049
Brugia malayi Thioredoxin reductase 0.0136 0.0419 0.0819
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0032 0.0062
Echinococcus multilocularis oxidoreductase 0.0013 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0006 0.0049
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0005 0.0009
Echinococcus granulosus 6 phosphofructokinase 0.024 0.0769 0.0769
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0013 0.0008 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0013 0.0008 0.0061
Schistosoma mansoni glucose transporter 0.0011 0.0001 0.0001
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0012 0.0006 0.0009
Toxoplasma gondii oxidoreductase, putative 0.0013 0.0008 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0108
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0012 0.0003 0.0007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1577 0.5243 1
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Loa Loa (eye worm) dehydrogenase 0.0013 0.0008 0.0015
Loa Loa (eye worm) helicase 0.0012 0.0005 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Onchocerca volvulus 0.1752 0.5831 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0114 0.1098
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0032 0.0032
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0082 0.031
Echinococcus multilocularis geminin 0.0359 0.1166 0.1166
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0031 0.006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Schistosoma mansoni aldehyde dehydrogenase 0.0014 0.0012 0.0012
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0194 0.0615 0.0615
Echinococcus multilocularis lamin dm0 0.0059 0.016 0.016
Loa Loa (eye worm) sugar transporter 0.0011 0.0001 0.0003
Echinococcus granulosus snurportin 1 0.0309 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0009
Onchocerca volvulus 0.0011 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0309 0.1 0.1954
Mycobacterium ulcerans 6-phosphofructokinase 0.024 0.0769 0.302
Leishmania major dehydrogenase-like protein 0.0013 0.0008 0.0061
Onchocerca volvulus 0.0092 0.0274 0.047
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.077 0.2543 1
Mycobacterium ulcerans glutaminase 0.0286 0.0923 0.3626
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0032 0.0032
Leishmania major NADH dehydrogenase, putative 0.0012 0.0006 0.0049
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0043 0.0072
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.016 0.0313
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0006
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0171 0.0171
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0012 0.0006 0.0049
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0012 0.0003 0.0007
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0012 0.0003 0.0007
Leishmania major cytochrome p450-like protein 0.0012 0.0003 0.0017
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0005 0.0038
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0072 0.0136
Trichomonas vaginalis mercuric reductase, putative 0.0047 0.0122 0.0207
Leishmania major hypothetical protein, conserved 0.0013 0.0008 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0041 0.0388
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0014 0.0012 0.0128
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.003 0.003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0031 0.0284
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0047 0.0122 0.2895
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.01 0.0299 0.0511
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0012 0.0003 0.0017
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0013 0.0008 0.0061
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0031 0.0056
Onchocerca volvulus 0.0011 0.0001 0.0002
Mycobacterium ulcerans NADH dehydrogenase 0.0012 0.0006 0.002
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0122 0.0208
Leishmania major ATP-dependent phosphofructokinase 0.024 0.0769 0.7487
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0062 0.0587
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0012 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Mycobacterium tuberculosis Probable oxidoreductase 0.0013 0.0008 0.0025
Loa Loa (eye worm) programmed cell death 8 0.0012 0.0006 0.0012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0008 0.0158
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0008 0.0013
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0035 0.0069
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.002 0.002
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0012 0.0006 0.002
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0013 0.0008 0.0018
Leishmania major cytochrome p450-like protein 0.0012 0.0003 0.0017
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.007 0.0136
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0124 0.038 0.038
Onchocerca volvulus 0.0011 0.0001 0.0002
Echinococcus multilocularis carbonyl reductase 1 0.0013 0.0008 0.0008
Plasmodium falciparum steroid dehydrogenase, putative 0.0013 0.0008 0.0158
Schistosoma mansoni steroid dehydrogenase 0.0013 0.0008 0.0008
Mycobacterium tuberculosis Probable dehydrogenase 0.031 0.1002 0.3937
Brugia malayi glutathione reductase 0.0136 0.0419 0.0819
Echinococcus granulosus hypothetical protein 0.0013 0.0008 0.0008
Plasmodium vivax SET domain containing protein 0.0014 0.0011 0.0135
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Brugia malayi glutaminase DH11.1 0.0286 0.0923 0.1803
Echinococcus granulosus solute carrier family 22 0.0011 0.0001 0.0001
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0005 0.0009
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0188 0.0188
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0012 0.0006 0.0009
Brugia malayi aldehyde dehydrogenase 0.0014 0.0012 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0129 0.1243
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0014 0.0012 0.0103
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0014 0.0012 0.0128
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Loa Loa (eye worm) heterochromatin protein 1 0.0012 0.0005 0.0009
Loa Loa (eye worm) dehydrogenase 0.0013 0.0008 0.0015
Brugia malayi phosphofructokinase 0.024 0.0769 0.1502
Mycobacterium ulcerans short-chain dehydrogenase 0.0013 0.0008 0.0025
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0074 0.0211 0.0413
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0012 0.0006 0.0006
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0065 0.0182 0.4324
Onchocerca volvulus 0.0011 0.0001 0.0002
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0191 0.0605 0.1181
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0012 0.0006 0.0006
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0013 0.0008 0.0013
Schistosoma mansoni DNA helicase recq5 0.0019 0.003 0.003
Brugia malayi 6-phosphofructokinase 0.024 0.0769 0.1502
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0344 0.1118 0.4392
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0117 0.0355 0.3451
Plasmodium vivax thioredoxin reductase, putative 0.0136 0.0419 0.59
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0005 0.0084
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.024 0.0769 0.3016
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0038
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0012 0.0003 0.0007
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0013 0.0008 0.0061
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0074 0.0211 0.0211
Schistosoma mansoni retinal dehydrogenase 0.0013 0.0008 0.0008
Echinococcus granulosus mitogen activated protein kinase 0.0117 0.0355 0.0355
Schistosoma mansoni glutamate synthase 0.0012 0.0006 0.0006
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0062 0.0062
Echinococcus granulosus solute carrier family 22 0.0011 0.0001 0.0001
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0134 0.0414 0.0414
Echinococcus multilocularis 0.0013 0.0008 0.0008
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0013 0.0008 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0299 0.2904
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.002 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0052
Echinococcus granulosus pyruvate kinase 0.0018 0.0025 0.0025
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0212 0.0676 0.0676
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0065 0.0182 0.4324
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0012 0.0006 0.0049
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0005 0.0005
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0049
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0041 0.096
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.003 0.003
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0014 0.0012 0.0023
Leishmania major phosphopantetheinyl transferase-like protein 0.0098 0.0291 0.2826
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0013 0.0008 0.0025
Echinococcus multilocularis lamin 0.0059 0.016 0.016
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0012 0.0006 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0013 0.0008 0.0025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0223 0.071 0.071
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0012 0.0006 0.0049
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0012 0.0006 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.0344 0.1118 0.4392
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0257 0.0825 0.0825
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0013 0.0008 0.0011
Brugia malayi major facilitator superfamily protein 0.0011 0.0001 0.0003
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.002 0.002
Echinococcus granulosus cpg binding protein 0.0098 0.0291 0.0291
Brugia malayi M-phase phosphoprotein, mpp8 0.0106 0.032 0.0624
Schistosoma mansoni glutaminase 0.0286 0.0923 0.0923
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.002 0.0177
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0014 0.0012 0.0041
Brugia malayi Pre-SET motif family protein 0.154 0.5119 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0036 0.0036
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0013 0.0008 0.0061
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.024 0.0769 0.302
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0012 0.0006 0.0173
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0124 0.038 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Echinococcus multilocularis pyruvate kinase 0.0035 0.0082 0.0082
Onchocerca volvulus 0.0013 0.0008 0.0013
Echinococcus granulosus mitogen activated protein kinase 3 0.0117 0.0355 0.0355
Onchocerca volvulus 0.0347 0.1126 0.193
Loa Loa (eye worm) hypothetical protein 0.0106 0.032 0.0624
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0467 0.4544
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0182 0.031
Brugia malayi hypothetical protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0012 0.0006 0.0012
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0012 0.0006 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.2998 1 1
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0025 0.0568
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0005 0.0084
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0126 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0122 0.1178
Brugia malayi hypothetical protein 0.002 0.0032 0.0062
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.002 0.0221
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Schistosoma mansoni pyruvate kinase 0.0035 0.0082 0.0082
Onchocerca volvulus 0.0059 0.016 0.0275
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0011 0.0001 0.0001
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0036 0.0337
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0223 0.071 0.071
Schistosoma mansoni carbonyl reductase 0.0013 0.0008 0.0008
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0082 0.0138
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0046 0.0091
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0012 0.0006 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.0299 0.2904
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0067 0.0188 0.0368
Leishmania major quinonoid dihydropteridine reductase 0.0013 0.0008 0.0061
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0032 0.0032
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0473 0.0923
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0102 0.2403
Brugia malayi Dehydrogenases, short chain protein 30 0.0013 0.0008 0.0015
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0013 0.0008 0.0011
Echinococcus multilocularis solute carrier family 22 0.0011 0.0001 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.006 0.1401
Trypanosoma brucei hypothetical protein, conserved 0.0098 0.0291 0.2826
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0094 0.028 0.028
Trichomonas vaginalis glutamate synthase, putative 0.0012 0.0006 0.0009
Trypanosoma brucei transcription factor BTF3, putative 0.0113 0.0342 0.3322
Trichomonas vaginalis dullard protein, putative 0.0013 0.0008 0.0011
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0082 0.0317
Brugia malayi Major Facilitator Superfamily protein 0.0011 0.0001 0.0003
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.002 0.0177
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0008 0.0025
Plasmodium falciparum importin beta, putative 0.0029 0.0062 0.1447
Echinococcus multilocularis chromobox protein 1 0.0012 0.0005 0.0005
Echinococcus multilocularis voltage dependent calcium channel 0.0097 0.0288 0.0288
Schistosoma mansoni sugar transporter 0.0011 0.0001 0.0001
Echinococcus multilocularis steroid dehydrogenase 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0038
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.1399 0.1399
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0035 0.0057
Mycobacterium ulcerans monoxygenase 0.0012 0.0006 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0075 0.0126
Schistosoma mansoni short chain dehydrogenase 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0062 0.0731
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0012 0.0003 0.0007
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0068 0.065
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0005 0.0038
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0013 0.0008 0.0061
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.006 0.1401
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0008 0.0076
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0233 0.2261
Brugia malayi dehydrogenases, short chain protein 2 0.0013 0.0008 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0012 0.0003 0.0007
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0014 0.0012 0.0103
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0072 0.0859
Brugia malayi Cytochrome P450 family protein 0.0031 0.0068 0.0133
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0014 0.0012 0.0021
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0012 0.0003 0.0007
Mycobacterium ulcerans short-chain dehydrogenase 0.0013 0.0008 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0012 0.0006 0.002
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0126 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0129 0.1243
Echinococcus granulosus hypothetical protein 0.0013 0.0008 0.0008
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0094 0.028 0.028
Echinococcus multilocularis pyruvate kinase 0.0018 0.0025 0.0025
Brugia malayi PXA domain containing protein 0.002 0.0032 0.0062
Echinococcus multilocularis histone lysine N methyltransferase SETD2 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0014 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Schistosoma mansoni glutamate synthase 0.0012 0.0006 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0005 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.024 0.0769 0.1465
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.024 0.0769 0.1456
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.006 0.0568
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0013 0.0008 0.0025
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.0122 0.4168
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0036 0.0488
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0025
Schistosoma mansoni ran 0.0021 0.0036 0.0036
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0014 0.0012 0.0012
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0013 0.0008 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0126 0.0247
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Trichomonas vaginalis glutaminase, putative 0.0286 0.0923 0.1581
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0041 0.0388
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0013 0.0008 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0041 0.0388
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0013 0.0008 0.0025
Trichomonas vaginalis dullard protein, putative 0.0013 0.0008 0.0011
Echinococcus multilocularis cpg binding protein 0.0098 0.0291 0.0291
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0011 0.0001 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.2998 1 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0036 0.007
Schistosoma mansoni glucose transport protein 0.0011 0.0001 0.0001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0013 0.0008 0.0013
Echinococcus granulosus pyruvate kinase 0.0035 0.0082 0.0082
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0012 0.0003 0.0017
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0035 0.0069
Leishmania major hypothetical protein, conserved 0.0012 0.0006 0.0049
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0013 0.0008 0.0217
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0122 0.1178
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0013 0.0008 0.0061
Schistosoma mansoni sulfide quinone reductase 0.0012 0.0006 0.0006
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0013 0.0008 0.0018
Brugia malayi jmjC domain containing protein 0.0016 0.002 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0005 0.0005
Schistosoma mansoni carbonyl reductase 0.0013 0.0008 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1577 0.5243 0.8992
Echinococcus granulosus dna polymerase kappa 0.01 0.0299 0.0299
Leishmania major cytochrome p450-like protein 0.0031 0.0068 0.065
Echinococcus granulosus pyruvate kinase 0.0035 0.0082 0.0082
Trypanosoma brucei short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0014 0.0012 0.0041
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0012 0.0006 0.0061
Toxoplasma gondii selenide, water dikinase 0.0012 0.0006 0.0061
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0097 0.0288 0.0562
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0114 0.0114
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0072 0.069
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0025 0.033
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0012 0.0003 0.0017
Loa Loa (eye worm) oxidoreductase 0.0013 0.0008 0.0015
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0014 0.0012 0.0034
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0013 0.0008 0.0061
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0003
Entamoeba histolytica short chain dehydrogenase family protein 0.0013 0.0008 0.0013
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0013 0.0008 0.0061
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0191 0.0605 0.0605
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0013 0.0008 0.0158
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0061
Schistosoma mansoni myst-related protein 0.0011 0.0001 0.0001
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0032 0.0032
Toxoplasma gondii phosphofructokinase PFKII 0.0065 0.0182 0.2191
Brugia malayi SET domain containing protein 0.0022 0.0038 0.0075

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -8.129 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.532 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.374 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.367 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.201 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.156 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.055 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.048 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.845 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.456 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.814 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
Log LC50 (ADMET) = -5.8 Concentration required for 50% lethality, evaluated on 60 different cancer cell line screens ChEMBL. 7837221
Ratio (functional) = 0.72 Ratio of the LC50 value of the compound to that of PBI-A. ChEMBL. 7837221

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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