Detailed information for compound 572000

Basic information

Technical information
  • TDR Targets ID: 572000
  • Name: (2R)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenyl-b utanoyl]amino]-4-methyl-pentanoic acid
  • MW: 308.373 | Formula: C16H24N2O4
  • H donors: 4 H acceptors: 4 LogP: -0.96 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H](C(=O)N[C@@H](C(=O)O)CC(C)C)[C@@H](Cc1ccccc1)N
  • InChi: 1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13-,14+/m1/s1
  • InChiKey: VGGGPCQERPFHOB-MCIONIFRSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-2-[[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]amino]-4-methylpentanoic acid
  • (2R)-2-[[(2S,3R)-3-azanyl-2-hydroxy-4-phenyl-butanoyl]amino]-4-methyl-pentanoic acid
  • (2R)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenyl-butanoyl]amino]-4-methyl-valeric acid
  • (2R)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid
  • bestatin
  • 58970-76-6
  • NCGC00161660-01
  • Bestatin (TN)
  • D00087
  • Ubenimex (JAN/INN)
  • UPCMLD-DP116:001
  • C00732
  • Ubenimex

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Leishmania major pyroglutamyl-peptidase I (C15 family) Curated by TDR Targets References
Plasmodium falciparum M17 leucyl aminopeptidase Curated by TDR Targets References
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Curated by TDR Targets References
Rattus norvegicus Aminopeptidase B Starlite/ChEMBL References
Plasmodium falciparum M1-family alanyl aminopeptidase Curated by TDR Targets References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum M1-family alanyl aminopeptidase Get druggable targets OG5_130542 All targets in OG5_130542
Trypanosoma cruzi pyroglutamyl-peptidase I, putative Get druggable targets OG5_150045 All targets in OG5_150045
Cryptosporidium parvum zincin/aminopeptidase N like metalloprotease Get druggable targets OG5_130542 All targets in OG5_130542
Plasmodium knowlesi M17 leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania donovani cytosolic leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Echinococcus multilocularis leucine aminopeptidase protein Get druggable targets OG5_127293 All targets in OG5_127293
Cryptosporidium hominis leucine aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma congolense metallo-peptidase, Clan MF, Family M17, putative Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium yoelii m1-family aminopeptidase Get druggable targets OG5_130542 All targets in OG5_130542
Toxoplasma gondii aminopeptidase n, putative Get druggable targets OG5_130542 All targets in OG5_130542
Leishmania mexicana cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium berghei M1-family alanyl aminopeptidase, putative Get druggable targets OG5_130542 All targets in OG5_130542
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 Get druggable targets OG5_150045 All targets in OG5_150045
Plasmodium yoelii putative leucine aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Toxoplasma gondii aminopeptidase N, putative Get druggable targets OG5_130542 All targets in OG5_130542
Mycobacterium ulcerans leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Theileria parva alpha-aminoacylpeptide hydrolase, putative Get druggable targets OG5_130542 All targets in OG5_130542
Neospora caninum Aminopeptidase N (EC 3.4.11.2), related Get druggable targets OG5_130542 All targets in OG5_130542
Trypanosoma brucei pyroglutamyl-peptidase I, putative Get druggable targets OG5_150045 All targets in OG5_150045
Babesia bovis leucine aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium falciparum M17 leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania braziliensis pyroglutamyl-peptidase I (PGP), putative Get druggable targets OG5_150045 All targets in OG5_150045
Trypanosoma brucei gambiense pyroglutamyl-peptidase I (PGP), putative,cysteine peptidase, Clan CF, family C15, putative Get druggable targets OG5_150045 All targets in OG5_150045
Leishmania infantum cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Neospora caninum hypothetical protein Get druggable targets OG5_130542 All targets in OG5_130542
Leishmania braziliensis cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania major pyroglutamyl-peptidase I (C15 family) Get druggable targets OG5_150045 All targets in OG5_150045
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania donovani pyroglutamyl-peptidase I, putative Get druggable targets OG5_150045 All targets in OG5_150045
Chlamydia trachomatis cytosol aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium knowlesi M1-family alanyl aminopeptidase, putative Get druggable targets OG5_130542 All targets in OG5_130542
Leishmania infantum pyroglutamyl-peptidase I (PGP), putative Get druggable targets OG5_150045 All targets in OG5_150045
Plasmodium vivax M17 leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Echinococcus granulosus leucine aminopeptidase protein Get druggable targets OG5_127293 All targets in OG5_127293
Mycobacterium tuberculosis Probable aminopeptidase PepB Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium berghei M17 leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma brucei gambiense cytosolic leucyl aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17, putative Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania mexicana pyroglutamyl-peptidase I (PGP), putative,cysteine peptidase, Clan CF, family C15, putative Get druggable targets OG5_150045 All targets in OG5_150045
Babesia bovis aminopeptidase, putative Get druggable targets OG5_130542 All targets in OG5_130542
Cryptosporidium parvum putative leucine aminopeptidase; of possible plant or bacterial origin Get druggable targets OG5_127293 All targets in OG5_127293
Mycobacterium leprae Probable cytosol aminopeptidase PepB Get druggable targets OG5_127293 All targets in OG5_127293
Theileria parva leucine aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Toxoplasma gondii leucyl aminopeptidase LAP Get druggable targets OG5_127293 All targets in OG5_127293
Toxoplasma gondii aminopeptidase N protein Get druggable targets OG5_130542 All targets in OG5_130542
Cryptosporidium hominis aminopeptidase N Get druggable targets OG5_130542 All targets in OG5_130542
Neospora caninum Probable cytosol aminopeptidase, related Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium vivax M1-family alanyl aminopeptidase, putative Get druggable targets OG5_130542 All targets in OG5_130542
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0045 0.002 0.0018
Brugia malayi AMP-binding enzyme family protein 0.004 0.0016 0.0101
Brugia malayi Sodium/hydrogen exchanger 8 0.005 0.0023 0.0148
Trypanosoma brucei histone deacetylase 1 0.0078 0.0043 0.049
Schistosoma mansoni tyrosine kinase 0.0144 0.009 0.0103
Schistosoma mansoni Slc9a7 protein 0.005 0.0023 0.0026
Plasmodium vivax histone deacetylase, putative 0.0034 0.0011 0.0178
Loa Loa (eye worm) hypothetical protein 0.0122 0.0074 0.0476
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0028 0.0007 0.0006
Echinococcus multilocularis neuropeptide FF receptor 2 0.1214 0.0851 0.549
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0007 0.0299
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Brugia malayi Sugar transporter family protein 0.0031 0.0009 0.006
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0085 0.0048 0.0306
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0081 0.3989
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0003 0.0022
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0009 0.006
Brugia malayi hypothetical protein 0.0024 0.0004 0.0027
Echinococcus multilocularis fmrfamide receptor 0.1214 0.0851 0.549
Trypanosoma cruzi Aminopeptidase M1, putative 0.0281 0.0187 0.214
Brugia malayi hypothetical protein 0.0385 0.0261 0.1681
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.004 0.0016 0.0014
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0385 0.0261 0.1681
Echinococcus multilocularis sodium:hydrogen exchanger 7 0.005 0.0023 0.0148
Plasmodium vivax aspartyl protease, putative 0.0023 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.1359 0.0955 0.6146
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0081 0.0519
Schistosoma mansoni hypothetical protein 0.0327 0.022 0.0252
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0024 0.0004 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0101
Echinococcus granulosus epidermal growth factor receptor 0.0078 0.0043 0.0276
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0178 0.0114 0.0734
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus glycylpeptide N tetradecanoyltransferase 0.0043 0.0018 0.0116
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0007 0.0046
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.0021 0.0133
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0425 0.029 0.3313
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Schistosoma mansoni hypothetical protein 0.022 0.0144 0.0165
Echinococcus granulosus glutamate receptor 2 0.0115 0.0069 0.0445
Plasmodium falciparum histone deacetylase 1 0.0078 0.0043 0.0709
Schistosoma mansoni hypothetical protein 0.1214 0.0851 0.0974
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0373 0.0253 0.1626
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0101
Echinococcus multilocularis tissue type plasminogen activator 0.0062 0.0031 0.0202
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0029 0.0008 0.0051
Echinococcus multilocularis histone deacetylase 6 0.0071 0.0038 0.0242
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Toxoplasma gondii sugar transporter ST2 0.0031 0.0009 0.0145
Echinococcus granulosus rho-associated protein kinase 1 0.0044 0.0019 0.0119
Schistosoma mansoni nAChR subunit 0.0385 0.0261 0.0299
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Plasmodium vivax aspartyl protease, putative 0.0023 0.0003 0.0045
Schistosoma mansoni tyrosine kinase 0.0078 0.0043 0.0049
Mycobacterium ulcerans thioesterase 0.0047 0.0021 0.002
Leishmania major hypothetical protein, conserved 0.0062 0.0031 0.0354
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0081 0.2547
Schistosoma mansoni sodium/chloride dependent transporter 0.0373 0.0253 0.0289
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0021 0.0002 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.1626
Schistosoma mansoni hypothetical protein 0.0056 0.0027 0.0031
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0 0.0003
Brugia malayi jmjC domain containing protein 0.0023 0.0003 0.0022
Schistosoma mansoni zinc finger protein 0.0024 0.0004 0.0005
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0023 0.0003 0.0045
Mycobacterium ulcerans hypothetical protein 0.004 0.0016 0.0014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0231 0.0152 0.0978
Brugia malayi aspartic protease BmAsp-2, identical 0.0023 0.0003 0.0021
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.006 0.003 0.0029
Echinococcus granulosus 7TM GPCR rhodopsin 0.1214 0.0851 0.549
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Mycobacterium leprae Polyketide synthase Pks13 0.0084 0.0047 0.0046
Echinococcus multilocularis JmjC domain containing protein 4 0.0023 0.0003 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0417
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0127 0.0078 0.0077
Trypanosoma cruzi histone deacetylase, putative 0.0071 0.0038 0.0424
Echinococcus multilocularis aminopeptidase N 0.0685 0.0475 0.3062
Leishmania major glucose transporter, lmgt2 0.0068 0.0036 0.0404
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0004 0.0025
Schistosoma mansoni hypothetical protein 0.0056 0.0027 0.0031
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0004 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Echinococcus granulosus mitochondrial sodium:hydrogen exchanger 9B2 0.005 0.0023 0.0148
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0213 0.0139 0.0897
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0264 0.0175 0.1125
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0009 0.0008
Echinococcus multilocularis solute carrier family 22 0.0031 0.0009 0.0059
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Schistosoma mansoni microtubule-associated protein tau 0.0777 0.054 0.0618
Leishmania major hypothetical protein, conserved 0.0031 0.0009 0.01
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0846 0.0589 0.3798
Mycobacterium tuberculosis Probable conserved integral membrane transport protein YjcE 0.005 0.0023 0.0022
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0281 0.0187 0.2142
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0084 0.0047 0.0046
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.1214 0.0851 0.0974
Echinococcus multilocularis histone deacetylase 8 0.0034 0.0011 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Echinococcus multilocularis leucyl aminopeptidase 0.0085 0.0048 0.0306
Mycobacterium leprae Probable polyketide synthase Pks1 0.006 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0016 0.0175
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni jumonji domain containing protein 0.0129 0.0079 0.009
Echinococcus granulosus neuropeptides capa receptor 0.1214 0.0851 0.549
Echinococcus multilocularis neuropeptide Y receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0085 0.0048 0.0306
Schistosoma mansoni sugar transporter 0.0031 0.0009 0.0011
Brugia malayi metabotropic glutamate receptor type 2 0.0021 0.0002 0.0014
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus 7tm_1 domain containing protein 0.1214 0.0851 0.549
Schistosoma mansoni N-myristoyltransferase 0.0043 0.0018 0.0021
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0846 0.0589 0.3798
Echinococcus granulosus tyrosine kinase 0.0023 0.0004 0.0025
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0264 0.0175 0.1128
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Echinococcus granulosus histone deacetylase 7 0.0071 0.0038 0.0242
Loa Loa (eye worm) matrixin family protein 0.0051 0.0023 0.0151
Brugia malayi glutaminase DH11.1 0.0301 0.0201 0.1296
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0117 0.007 0.0454
Loa Loa (eye worm) hypothetical protein 0.0157 0.0099 0.0637
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0004 0.0005
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0004 0.0027
Loa Loa (eye worm) solute carrier family 6 member 4 0.2197 0.1551 0.9983
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0019 0.0001 0.0001
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0038 0.0431
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Schistosoma mansoni alpha-1 adrenergic receptor 0.1214 0.0851 0.0974
Treponema pallidum sodium- and chloride- dependent transporter 0.2197 0.1551 1
Schistosoma mansoni alpha glucosidase 0.0024 0.0004 0.0005
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.001 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.001 0.0151
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.003 0.0009 0.0057
Mycobacterium ulcerans sugar transporter 0.0031 0.0009 0.0008
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0104 0.0061 0.0395
Schistosoma mansoni hypothetical protein 0.005 0.0023 0.0026
Brugia malayi G-protein coupled receptor 0.1214 0.0851 0.5481
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0038 0.0244
Trichomonas vaginalis N-myristoyl transferase, putative 0.0028 0.0008 0.0345
Brugia malayi Hemopexin family protein 0.003 0.0009 0.0055
Schistosoma mansoni jumonji/arid domain-containing protein 0.009 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Plasmodium falciparum glutathione reductase 0.0024 0.0004 0.0062
Loa Loa (eye worm) aminopeptidase N 0.0281 0.0187 0.1205
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Loa Loa (eye worm) N-myristoyltransferase 2 0.0043 0.0018 0.0116
Brugia malayi GnHR receptor homolog 0.1393 0.0978 0.6298
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0009 0.0216
Onchocerca volvulus 0.0031 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0425 0.029 0.3315
Schistosoma mansoni apoferritin-2 0.002 0.0001 0.0001
Brugia malayi Matrixin family protein 0.0021 0.0002 0.0014
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.001 0.0314
Leishmania major hypothetical protein, conserved 0.0023 0.0003 0.0033
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0002 0.0014
Echinococcus multilocularis neuropeptide receptor 0.1214 0.0851 0.549
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0165 0.8178
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0 0.0003
Echinococcus granulosus microtubule associated protein 2 0.0777 0.054 0.3482
Echinococcus multilocularis FTZ F1 alpha 0.0019 0 0.0003
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0081 0.0092
Echinococcus multilocularis tyrosine kinase 0.0023 0.0004 0.0025
Echinococcus granulosus histone deacetylase 6 0.0071 0.0038 0.0242
Brugia malayi Bromodomain containing protein 0.0083 0.0047 0.03
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Brugia malayi Muscleblind-like protein 0.0276 0.0184 0.1183
Leishmania major histone deacetylase, putative 0.0078 0.0043 0.0488
Onchocerca volvulus Alhambra homolog 0.0031 0.001 0.0059
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0009 0.0102
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.1214 0.0851 0.0974
Schistosoma mansoni carboxypeptidase N (M14 family) 0.0076 0.0041 0.0047
Brugia malayi Tyrosine-protein kinase abl-1 0.0238 0.0157 0.101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0004 0.0004
Schistosoma mansoni metabotropic glutamate receptor 0.0021 0.0002 0.0003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.1214 0.0851 0.549
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0056 0.0027 0.0026
Brugia malayi Matrixin family protein 0.0021 0.0002 0.0014
Loa Loa (eye worm) CYP4Cod1 0.0147 0.0092 0.059
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0081 0.0921
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Brugia malayi Integrin beta pat-3 precursor 0.0203 0.0132 0.0848
Entamoeba histolytica hypothetical protein 0.0021 0.0002 0.0054
Brugia malayi G protein-coupled receptor F59B2.13 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Onchocerca volvulus 0.0031 0.0009 0.0057
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Brugia malayi hypothetical protein 0.0184 0.0118 0.0762
Mycobacterium ulcerans polyketide synthase Pks13 0.0084 0.0047 0.0046
Trypanosoma cruzi sodium/hydrogen exchanger, putative 0.005 0.0023 0.0258
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0 0.0002
Brugia malayi Glycosyl hydrolases family 31 protein 0.0108 0.0064 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.000005704 0.0000065289
Trypanosoma brucei aminopeptidase, putative 0.0085 0.0048 0.054
Echinococcus multilocularis muscleblind protein 0.0276 0.0184 0.1185
Echinococcus multilocularis lysosomal alpha glucosidase 0.0108 0.0064 0.0413
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0373 0.0253 0.0289
Toxoplasma gondii subtilisin SUB12 0.0021 0.0003 0.0032
Brugia malayi Tyrosine-protein kinase abl-1 0.0161 0.0102 0.0656
Brugia malayi neuropeptide F receptor 0.1214 0.0851 0.5481
Echinococcus granulosus dna polymerase eta 0.003 0.0009 0.0055
Echinococcus granulosus ferritin 0.002 0.0001 0.0008
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0078 0.0043 0.2118
Brugia malayi Cytochrome P450 family protein 0.0147 0.0092 0.059
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0127 0.0078 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Mycobacterium leprae PROBABLE HYDROLASE 0.0026 0.0006 0.0004
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.003 0.0009 0.0057
Brugia malayi Protein kinase domain containing protein 0.0064 0.0033 0.0213
Echinococcus multilocularis g protein coupled receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0385 0.0261 0.1684
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Schistosoma mansoni neurotransmitter gated ion channel 0.0385 0.0261 0.0299
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Loa Loa (eye worm) glutaminase 0.0301 0.0201 0.1296
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0004 0.0003
Echinococcus granulosus JmjC domain containing protein 4 0.0023 0.0003 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0 0.0003
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.001 0.0151
Echinococcus granulosus g protein coupled receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Echinococcus multilocularis histone deacetylase 6 0.0073 0.0039 0.0251
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0013 0.0199
Brugia malayi Sugar transporter family protein 0.0031 0.0009 0.006
Onchocerca volvulus 0.1214 0.0851 0.5489
Echinococcus granulosus histone deacetylase 6 0.0071 0.0038 0.0242
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.001 0.0452
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0012 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0127 0.0078 0.0077
Trichomonas vaginalis alpha-glucosidase, putative 0.0024 0.0004 0.0187
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0023 0.0003 0.0035
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.006 0.003 0.0029
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0028 0.0007 0.0044
Plasmodium falciparum sodium/hydrogen exchanger, Na+, H+ antiporter 0.005 0.0023 0.0375
Echinococcus granulosus metabotropic glutamate receptor 5 0.0021 0.0002 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0062 0.0031 0.0202
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0022
Loa Loa (eye worm) norepinephrine transporter 0.2197 0.1551 0.9983
Loa Loa (eye worm) latrophilin receptor protein 2 0.0056 0.0027 0.0176
Onchocerca volvulus 0.0846 0.0589 0.3796
Loa Loa (eye worm) hypothetical protein 0.2197 0.1551 0.9983
Onchocerca volvulus 0.0685 0.0475 0.306
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0036 0.0404
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.004 0.0016 0.0015
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0038 0.0244
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0059 0.0029 0.0187
Brugia malayi Subtilase family protein 0.0136 0.0084 0.0541
Trichomonas vaginalis alpha-glucosidase, putative 0.0024 0.0004 0.0187
Trichomonas vaginalis glutaminase, putative 0.0301 0.0201 1
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus neuropeptide FF receptor 2 0.1214 0.0851 0.549
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0004 0.0027
Echinococcus multilocularis expressed conserved protein 0.0051 0.0023 0.015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0035 0.0225
Trypanosoma cruzi aminopeptidase, putative 0.0144 0.009 0.1026
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0009 0.0145
Brugia malayi RE15519p 0.1214 0.0851 0.5481
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0021 0.0002 0.0014
Trypanosoma cruzi zinc carboxypeptidase, putative 0.0076 0.0041 0.0465
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0373 0.0253 0.6744
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0036 0.1755
Loa Loa (eye worm) zinc carboxypeptidase 0.0076 0.0041 0.0264
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0846 0.0589 0.0674
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0021
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.01 0.0058 0.0665
Loa Loa (eye worm) acyl carrier protein 0.0026 0.0006 0.0037
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0013 0.0199
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0009 0.0096
Schistosoma mansoni ferritin 0.002 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0127 0.0078 0.0077
Brugia malayi excitatory GABA receptor EXP-1A 0.0846 0.0589 0.3792
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0009 0.0096
Echinococcus multilocularis leucyl aminopeptidase 0.0085 0.0048 0.0306
Loa Loa (eye worm) hypothetical protein 0.0365 0.0247 0.1591
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0519 0.0356 0.408
Brugia malayi Kringle domain containing protein 0.0062 0.0031 0.0202
Echinococcus granulosus geminin 0.0332 0.0224 0.1442
Brugia malayi ecdysteroid receptor 0.0019 0 0.0003
Brugia malayi MBOAT family protein 0.0019 0.0001 0.0003
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0281 0.0187 0.0214
Loa Loa (eye worm) peptidase family M1 containing protein 0.0548 0.0378 0.2431
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0006 0.0041
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0846 0.0589 0.3792
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0385 0.0261 0.1681
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0013 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0036 0.1755
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0018 0.0118
Schistosoma mansoni acetylcholine receptor-related 0.0385 0.0261 0.0299
Echinococcus granulosus c-Jun N-terminal kinases 0.0104 0.0061 0.0395
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1214 0.0851 0.549
Trypanosoma brucei Aminopeptidase M1, putative 0.0281 0.0187 0.2142
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0056 0.0027 0.0026
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0078 0.0043 0.2118
Loa Loa (eye worm) TK/EGFR protein kinase 0.0144 0.009 0.0577
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Loa Loa (eye worm) MBOAT family protein 0.0019 0.0001 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0117 0.007 0.0069
Echinococcus multilocularis lysine specific demethylase 6a 0.0023 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Echinococcus granulosus cpg binding protein 0.0048 0.0021 0.0137
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0066 0.0034 0.0221
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0081 0.0519
Brugia malayi diacylglycerol acyltransferase 0.0019 0.0001 0.0003
Echinococcus multilocularis nmda type glutamate receptor 0.0181 0.0116 0.0747
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0066 0.0034 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0 0.0003
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0032 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Onchocerca volvulus 0.003 0.0009 0.0052
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Onchocerca volvulus 0.1214 0.0851 0.5489
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.011 0.0065 0.042
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0038 0.0244
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0846 0.0589 0.3798
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0066 0.0034 0.0221
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0009 0.0059
Leishmania major cytochrome p450-like protein 0.0127 0.0078 0.0887
Echinococcus multilocularis nAChR subunit 0.0461 0.0315 0.2031
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Loa Loa (eye worm) hypothetical protein 0.1359 0.0955 0.6146
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0024 0.0005 0.0046
Schistosoma mansoni ferritin 0.002 0.0001 0.0001
Echinococcus granulosus o acyltransferase membrane bound domain 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0157 0.0099 0.0098
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0037 0.0014 0.0013
Leishmania major Na/H antiporter-like protein 0.005 0.0023 0.0258
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0181 0.0116 0.0748
Schistosoma mansoni histone deacetylase 0.0078 0.0043 0.0049
Entamoeba histolytica Flap nuclease, putative 0.0031 0.001 0.0289
Schistosoma mansoni sodium/chloride dependent transporter 0.0374 0.0253 0.029
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Trypanosoma cruzi cytochrome P450, putative 0.0147 0.0092 0.1044
Onchocerca volvulus 0.0461 0.0315 0.2029
Mycobacterium ulcerans leucyl aminopeptidase 0.0541 0.0373 0.0371
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Echinococcus multilocularis thioredoxin glutathione reductase 0.0069 0.0037 0.0236
Toxoplasma gondii thioredoxin reductase 0.0069 0.0036 0.0596
Schistosoma mansoni glutamate receptor kainate 0.016 0.0101 0.0116
Schistosoma mansoni lozenge 0.0023 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0846 0.0589 0.3791
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0009 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0127 0.0078 0.0077
Onchocerca volvulus Matrilysin homolog 0.0047 0.0021 0.0129
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Schistosoma mansoni hypothetical protein 0.0403 0.0274 0.0314
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0181 0.0116 0.0748
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0 0.0003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.2197 0.1551 0.9983
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Onchocerca volvulus 0.0059 0.0029 0.0185
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.0028 0.0032
Echinococcus multilocularis serotonin receptor 0.1214 0.0851 0.549
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0127 0.0078 0.0887
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0264 0.0175 0.1126
Brugia malayi CXXC zinc finger family protein 0.0043 0.0018 0.0116
Echinococcus granulosus dro:myosuppressin receptor 0.1214 0.0851 0.549
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0519 0.0356 0.408
Schistosoma mansoni tyrosine kinase 0.0076 0.0041 0.0047
Mycobacterium tuberculosis Probable oxidoreductase 0.0175 0.0112 0.0111
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0013 0.0223
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) serotonin transporter b 0.2197 0.1551 0.9983
Brugia malayi hypothetical protein 0.0023 0.0003 0.0021
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0009 0.01
Loa Loa (eye worm) neuropeptide F receptor 0.1214 0.0851 0.5481
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0178 0.0114 0.0734
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.0081 0.052
Schistosoma mansoni aldehyde dehydrogenase 0.0117 0.007 0.0081
Echinococcus granulosus cytosolic carboxypeptidase protein 5 0.0076 0.0041 0.0265
Onchocerca volvulus Subfamily M14A unassigned peptidase homolog 0.0441 0.0301 0.1939
Echinococcus multilocularis dnaJ subfamily B 0.0327 0.022 0.142
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0066 0.0034 0.0217
Plasmodium falciparum plasmepsin III 0.0023 0.0003 0.0045
Echinococcus multilocularis neuropeptide s receptor 0.1582 0.1113 0.7179
Loa Loa (eye worm) hypothetical protein 0.0276 0.0184 0.1183
Onchocerca volvulus 0.1214 0.0851 0.5489
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.2107 0.1486 0.9585
Trypanosoma brucei glycerol uptake protein, putative 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0019 0.0001 0.0001
Plasmodium falciparum cysteine repeat modular protein 1 0.0062 0.0031 0.0514
Entamoeba histolytica sodium/proton antiporter, putative 0.005 0.0023 0.0715
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0057 0.0028 0.1362
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0037 0.0014 0.009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0007 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.0191 0.0123 0.0794
Brugia malayi jmjC domain containing protein 0.0023 0.0003 0.0022
Schistosoma mansoni flap endonuclease-1 0.0028 0.0008 0.0009
Trypanosoma cruzi sodium/hydrogen exchanger, putative 0.005 0.0023 0.0258
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.001 0.0062
Plasmodium falciparum thioredoxin reductase 0.0024 0.0004 0.0062
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.01 0.0058 0.0663
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0009 0.0011
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0021 0.0002 0.0014
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0004 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.0117 0.007 0.0081
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0009 0.0059
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0021 0.0002 0.0014
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0281 0.0187 0.214
Brugia malayi Hhat protein 0.0019 0.0001 0.0003
Onchocerca volvulus 0.0031 0.0009 0.0057
Brugia malayi AKH receptor 0.1214 0.0851 0.5481
Schistosoma mansoni metabotropic glutamate receptor 0.0021 0.0002 0.0003
Echinococcus multilocularis dna polymerase kappa 0.004 0.0016 0.0101
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14 0.0076 0.0041 0.0465
Entamoeba histolytica sodium/proton antiporter, putative 0.005 0.0023 0.0715
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.001 0.0011
Schistosoma mansoni apoferritin-2 0.002 0.0001 0.0001
Onchocerca volvulus 0.0385 0.0261 0.1682
Echinococcus multilocularis sodium:hydrogen exchanger 0.0264 0.0175 0.1128
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0029 0.0008 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Plasmodium falciparum flap endonuclease 1 0.0031 0.001 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0165 0.8178
Onchocerca volvulus 0.0184 0.0118 0.0761
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0 0.0003
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.0081 0.008
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0095 0.0055 0.0351
Onchocerca volvulus 0.0031 0.0009 0.0057
Giardia lamblia Fructose-bisphosphate aldolase 0.0206 0.0134 0.7614
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0018 0.0117
Schistosoma mansoni ferritin light chain 0.002 0.0001 0.0001
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0047 0.0021 0.002
Echinococcus multilocularis SAM and MBT domain containing protein 0.0066 0.0034 0.022
Plasmodium falciparum plasmepsin VI 0.0057 0.0028 0.0456
Mycobacterium tuberculosis Probable histidinol dehydrogenase HisD (HDH) 1.4071 1 1
Echinococcus granulosus Squalene phytoene synthase 0.0388 0.0263 0.1698
Echinococcus multilocularis somatostatin receptor 0.1214 0.0851 0.549
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0157 0.0099 0.0098
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0025 0.016
Trypanosoma cruzi N-myristoyl transferase, putative 0.0043 0.0018 0.0201
Brugia malayi hypothetical protein 0.0031 0.0009 0.006
Onchocerca volvulus Matrilysin homolog 0.0021 0.0002 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0025 0.0028
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0127 0.0078 0.0077
Plasmodium vivax aspartyl proteinase, putative 0.0023 0.0003 0.0045
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0037 0.0013 0.0213
Echinococcus granulosus neuropeptide receptor A26 0.1582 0.1113 0.7179
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0009 0.01
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Loa Loa (eye worm) melatonin receptor type 1A 0.1214 0.0851 0.5481
Echinococcus granulosus integrin beta 2 0.015 0.0094 0.0608
Echinococcus granulosus phd:f box containing protein 0.0023 0.0003 0.0022
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0 0.0003
Onchocerca volvulus 0.1214 0.0851 0.5489
Onchocerca volvulus 0.1214 0.0851 0.5489
Echinococcus multilocularis jumonji domain containing 1A 0.0023 0.0003 0.0022
Schistosoma mansoni alpha-glucosidase 0.0093 0.0053 0.0061
Loa Loa (eye worm) POT family protein 0.0049 0.0022 0.0143
Brugia malayi Tachykinin-like peptides receptor 99D 0.1214 0.0851 0.5481
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0023 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Schistosoma mansoni biogenic amine receptor 0.1214 0.0851 0.0974
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.001 0.0062
Echinococcus granulosus leucyl aminopeptidase 0.0085 0.0048 0.0306
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Echinococcus multilocularis zinc finger protein 0.0024 0.0004 0.0026
Echinococcus granulosus o acyltransferase membrane bound domain 0.0019 0.0001 0.0003
Trypanosoma brucei histone deacetylase 3 0.0071 0.0038 0.0426
Trypanosoma cruzi Carboxypeptidase-like protein 0.0076 0.0041 0.0465
Loa Loa (eye worm) neuropeptide F receptor 0.1214 0.0851 0.5481
Echinococcus multilocularis integrin alpha 3 0.0076 0.0041 0.0266
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0846 0.0589 0.0674
Trypanosoma brucei sugar transporter, putative 0.0031 0.0009 0.0102
Trichomonas vaginalis maltase-glucoamylase, putative 0.0024 0.0004 0.0187
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0846 0.0589 0.3798
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0263 0.0174 0.1123
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0036 0.1755
Echinococcus granulosus expressed protein 0.002 0.0001 0.0008
Echinococcus granulosus aminopeptidase N 0.0685 0.0475 0.3062
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0049 0.0022 0.0025
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0036 0.1755
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0136 0.0084 0.0096
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Brugia malayi hypothetical protein 0.0385 0.0261 0.1681
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0 0.0003
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0019 0.0001 0.0003
Schistosoma mansoni histone deacetylase hda2 0.0034 0.0011 0.0013
Brugia malayi Matrixin family protein 0.0021 0.0002 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0012 0.0186
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.1214 0.0851 0.549
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0036 0.1755
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0147 0.0092 0.009
Entamoeba histolytica glycylpeptide N-tetradecanoyltransferase, putative 0.0043 0.0018 0.0556
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0009 0.0434
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.006 0.003 0.0029
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.2107 0.1486 0.9569
Echinococcus granulosus G protein coupled receptor 139 0.1214 0.0851 0.549
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Echinococcus multilocularis ferritin 0.002 0.0001 0.0008
Leishmania major glucose transporter/membrane transporter D2, putative 0.0068 0.0036 0.0404
Onchocerca volvulus 0.0044 0.0019 0.0117
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0045 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Echinococcus granulosus histone acetyltransferase MYST2 0.0075 0.0041 0.0262
Schistosoma mansoni hypothetical protein 0.0127 0.0078 0.0089
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0028 0.0007 0.0086
Onchocerca volvulus 0.0281 0.0187 0.1205
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0038 0.0429
Onchocerca volvulus 0.1214 0.0851 0.5489
Mycobacterium ulcerans ion antiporter, NhaP 0.005 0.0023 0.0022
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0036 0.0404
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0001 0.0013
Loa Loa (eye worm) histone deacetylase 7A 0.0071 0.0038 0.0241
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0846 0.0589 0.3798
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0 0.0003
Echinococcus multilocularis G protein coupled receptor 139 0.1214 0.0851 0.549
Onchocerca volvulus 0.0031 0.0009 0.0057
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0028 0.0007 0.0044
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0019 0.0001 0.0003
Echinococcus multilocularis dna polymerase eta 0.003 0.0009 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Mycobacterium tuberculosis Probable dehydrogenase 0.0157 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0137 0.0084 0.0544
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Loa Loa (eye worm) hypothetical protein 0.0137 0.0084 0.0544
Onchocerca volvulus 0.005 0.0023 0.0146
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0127 0.0078 0.0077
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0373 0.0253 0.0289
Echinococcus granulosus allatostatin A receptor 0.1214 0.0851 0.549
Echinococcus multilocularis NMDA receptor 0.0066 0.0034 0.0221
Schistosoma mansoni sodium/chloride dependent transporter 0.2197 0.1551 0.1775
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.011 0.545
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.0081 0.0079
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0181 0.0116 0.0748
Echinococcus granulosus biogenic amine 5HT receptor 0.1214 0.0851 0.549
Onchocerca volvulus 0.0021 0.0002 0.0012
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0846 0.0589 0.3792
Schistosoma mansoni opsin-like receptor 0.1214 0.0851 0.0974
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0281 0.0187 0.214
Onchocerca volvulus 0.0031 0.0009 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0025 0.016
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.0538
Echinococcus granulosus neuropeptide s receptor 0.1582 0.1113 0.7179
Echinococcus multilocularis integrin alpha ps 0.0044 0.0019 0.0122
Echinococcus granulosus glutamate NMDA receptor subunit 0.0354 0.0239 0.1542
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0013 0.0595
Entamoeba histolytica hypothetical protein 0.0043 0.0018 0.056
Onchocerca volvulus 0.0846 0.0589 0.3796
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0009 0.0434
Brugia malayi Receptor family ligand binding region containing protein 0.0021 0.0002 0.0014
Echinococcus granulosus somatostatin receptor 0.1214 0.0851 0.549
Echinococcus multilocularis insulin receptor 0.0047 0.0021 0.0133
Brugia malayi jmjC domain containing protein 0.015 0.0094 0.0606
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0003 0.002
Trypanosoma cruzi squalene synthase, putative 0.1244 0.0873 1
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0519 0.0356 0.408
Echinococcus multilocularis geminin 0.0332 0.0224 0.1442
Leishmania major cytochrome p450-like protein 0.0127 0.0078 0.0887
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.005 0.0023 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0013 0.0595
Echinococcus granulosus leucyl aminopeptidase 0.0085 0.0048 0.0306
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0846 0.0589 0.3798
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0024
Echinococcus multilocularis nmda type glutamate receptor 0.0254 0.0168 0.1084
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0013 0.0199
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0006 0.0041
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Schistosoma mansoni nAChR subunit 0.0385 0.0261 0.0299
Loa Loa (eye worm) TATA binding protein associated factor 0.0144 0.009 0.0579
Brugia malayi 6-phosphofructokinase 0.0131 0.0081 0.0519
Echinococcus granulosus tm gpcr rhodopsin 0.1214 0.0851 0.549
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0006 0.0067
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.1626
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0 0.0003
Brugia malayi nuclear receptor NHR-88 0.0019 0 0.0003
Trypanosoma cruzi Na/H antiporter-like protein, putative 0.005 0.0023 0.0258
Onchocerca volvulus 0.0066 0.0034 0.0217
Loa Loa (eye worm) hypothetical protein 0.0078 0.0043 0.0274
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.2197 0.1551 0.1775
Brugia malayi PHD-finger family protein 0.0029 0.0008 0.0052
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0019 0.0001 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0041 0.0676
Echinococcus multilocularis sterol O acyltransferase 1 0.0191 0.0123 0.0795
Schistosoma mansoni protein kinase 0.004 0.0016 0.0018
Echinococcus granulosus zinc finger protein 0.0024 0.0004 0.0026
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0077 0.0042 0.0269
Brugia malayi Matrixin family protein 0.0021 0.0002 0.0014
Echinococcus granulosus leucine aminopeptidase protein 0.0541 0.0373 0.2403
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0461 0.0315 0.2028
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.022 0.0144 0.0927
Leishmania major hypothetical protein, conserved 0.0388 0.0263 0.3012
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Brugia malayi Carboxypeptidase A2 precursor 0.0076 0.0041 0.0265
Loa Loa (eye worm) glutamate receptor 2 0.016 0.0101 0.0651
Brugia malayi Eukaryotic aspartyl protease family protein 0.0023 0.0003 0.0021
Loa Loa (eye worm) thioredoxin reductase 0.0069 0.0036 0.0234
Echinococcus multilocularis neuropeptide receptor 0.1214 0.0851 0.549
Schistosoma mansoni sugar transporter 0.0031 0.0009 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0004 0.0043
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0019 0.0001 0.0003
Schistosoma mansoni neuropeptide receptor 0.1214 0.0851 0.0974
Plasmodium falciparum glutathione reductase 0.0069 0.0036 0.0596
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0004 0.0185
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0165 0.8178
Entamoeba histolytica aminopeptidase, putative 0.0281 0.0187 0.5937
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0846 0.0589 0.3791
Brugia malayi Integrin alpha pat-2 precursor 0.0099 0.0058 0.0372
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.001 0.0151
Echinococcus granulosus glycine receptor subunit beta 0.0846 0.0589 0.3798
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0081 0.0092
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0056 0.0027 0.0176
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0075 0.0041 0.0262
Toxoplasma gondii sugar transporter ST3 0.0031 0.0009 0.0145
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Plasmodium falciparum JmjC domain-containing protein, putative 0.0023 0.0003 0.0048
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Echinococcus multilocularis receptor type guanylyl cyclase 0.0023 0.0004 0.0025
Echinococcus multilocularis ubiquitin specific protease 41 0.003 0.0009 0.0057
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.01 0.0058 0.0663
Schistosoma mansoni growth hormone secretagogue receptor 0.1214 0.0851 0.0974
Schistosoma mansoni hypothetical protein 0.0332 0.0224 0.0256
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0137 0.0084 0.0097
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0665 0.046 0.2969
Brugia malayi Peptidase family M1 containing protein 0.0144 0.009 0.058
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Echinococcus multilocularis glycylpeptide N tetradecanoyltransferase 0.0043 0.0018 0.0116
Toxoplasma gondii histone deacetylase HDAC1 0.0071 0.0038 0.0616
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.2107 0.1486 0.9585
Brugia malayi POT family protein 0.0049 0.0022 0.0144
Brugia malayi gonadotropin-releasing hormone receptor 2 0.1214 0.0851 0.5481
Mycobacterium ulcerans aldehyde dehydrogenase 0.0117 0.007 0.0069
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0019 0.0001 0.0001
Loa Loa (eye worm) TK/ROR protein kinase 0.0064 0.0033 0.0213
Echinococcus multilocularis orexin receptor type 2 0.1214 0.0851 0.549
Toxoplasma gondii aspartyl protease ASP3 0.0023 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Leishmania major N-myristoyl transferase, putative 0.0043 0.0018 0.0201
Schistosoma mansoni neuropeptide F-like receptor 0.1214 0.0851 0.0974
Schistosoma mansoni adenoreceptor 0.1214 0.0851 0.0974
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0 0.0003
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0127 0.0078 0.0077
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0846 0.0589 0.0674
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0385 0.0261 0.1684
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.1626
Brugia malayi Steroid receptor seven-up type 2 0.0019 0 0.0003
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0181 0.0116 0.0748
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.001 0.0104
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0385 0.0261 0.1681
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0009 0.0434
Plasmodium falciparum transporter, putative 0.0373 0.0253 0.4199
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.1214 0.0851 0.5481
Trypanosoma brucei Aminopeptidase M1, putative 0.0281 0.0187 0.2142
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0013 0.0595
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0051 0.0024 0.0151
Trypanosoma brucei glucose transporter 2A 0.0068 0.0036 0.0406
Entamoeba histolytica acyl-CoA synthetase, putative 0.004 0.0016 0.0482
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0075 0.0041 0.0261
Echinococcus granulosus sodium and chloride dependent glycine 0.0373 0.0253 0.1629
Onchocerca volvulus 0.0385 0.0261 0.1682
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.003 0.0009 0.0136
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.001 0.0062
Brugia malayi cytosol aminopeptidase 0.0085 0.0048 0.0306
Schistosoma mansoni neuropeptide F-like receptor 0.1214 0.0851 0.0974
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0023 0.0003 0.0004
Schistosoma mansoni alpha-glucosidase 0.0093 0.0053 0.0061
Loa Loa (eye worm) sugar transporter 0.0031 0.0009 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0 0.0003
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0144 0.009 0.4456
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.0044 0.0019 0.0119
Schistosoma mansoni leucine aminopeptidase 0.0085 0.0048 0.0054
Brugia malayi Bromodomain containing protein 0.0034 0.0011 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0006
Plasmodium vivax plasmepsin IV, putative 0.0057 0.0028 0.0456
Brugia malayi G protein-coupled receptor 0.1214 0.0851 0.5481
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0051 0.0326
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0007 0.0299
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0385 0.0261 0.1681
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.1214 0.0851 0.5481
Brugia malayi hypothetical protein 0.0385 0.0261 0.1681
Loa Loa (eye worm) hypothetical protein 0.0097 0.0056 0.036
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.0538
Onchocerca volvulus 0.1214 0.0851 0.5489
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0009 0.0434
Schistosoma mansoni histamine h1 receptor 0.1214 0.0851 0.0974
Loa Loa (eye worm) NHE-3 0.0264 0.0175 0.1126
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.001 0.0104
Brugia malayi AMP-binding enzyme family protein 0.004 0.0016 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0009 0.0434
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0541 0.0373 0.6197
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0004 0.0062
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0846 0.0589 0.3791
Echinococcus multilocularis sodium and chloride dependent glycine 0.0373 0.0253 0.1629
Onchocerca volvulus 0.0031 0.0009 0.0057
Echinococcus multilocularis lysosomal alpha glucosidase 0.0108 0.0064 0.0413
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0373 0.0253 0.1629
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0004 0.0025
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0135 0.0084 0.0538
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0016 0.0173
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0083 0.0047 0.0301
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0373 0.0253 0.0289
Brugia malayi Flap endonuclease-1 0.0031 0.001 0.0062
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0104 0.0061 0.0394
Echinococcus multilocularis glutamate receptor 2 0.0115 0.0069 0.0445
Trypanosoma brucei hypothetical protein, conserved 0.01 0.0058 0.0665
Schistosoma mansoni phd/f-box containing protein 0.0023 0.0003 0.0004
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0127 0.0078 0.0077
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0019 0.0001 0.0003
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0019 0.0001 0.0001
Schistosoma mansoni glutamate receptor AMPA 0.016 0.0101 0.0116
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0249 0.0165 0.1061
Echinococcus multilocularis leucyl aminopeptidase 0.0085 0.0048 0.0306
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0144 0.009 0.1026
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0056 0.0027 0.0026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0056 0.0027 0.0176
Schistosoma mansoni hypothetical protein 0.0022 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Onchocerca volvulus 0.0846 0.0589 0.3796
Schistosoma mansoni hypothetical protein 0.005 0.0023 0.0026
Brugia malayi PHD-finger family protein 0.0031 0.001 0.0062
Echinococcus granulosus subfamily M14A unassigned peptidase 0.0441 0.0301 0.1941
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0157 0.0099 0.0098
Brugia malayi Cytochrome P450 family protein 0.0127 0.0078 0.0502
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0846 0.0589 0.3792
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0846 0.0589 0.0674
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.4199
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0004 0.0082
Echinococcus multilocularis L aminoadipate semialdehyde 0.0059 0.0029 0.0187
Trypanosoma cruzi Na/H antiporter-like protein, putative 0.005 0.0023 0.0258
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0004 0.0082
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0076 0.0041 0.216
Leishmania major squalene synthase, putative 0.1244 0.0873 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Loa Loa (eye worm) fatty acid synthase 0.0056 0.0027 0.0173
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0206 0.0134 0.4249
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0019 0.0001 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.003 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.015 0.0094 0.0605
Onchocerca volvulus 0.005 0.0023 0.0146
Brugia malayi larval opioid receptor 0.1214 0.0851 0.5481
Brugia malayi cytochrome P450 0.0127 0.0078 0.0502
Echinococcus multilocularis alpha 1A adrenergic receptor 0.1214 0.0851 0.549
Brugia malayi histone deacetylase 11 0.0034 0.0011 0.0072
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Giardia lamblia Sugar-proton symporter 0.0031 0.0009 0.0293
Brugia malayi N-myristoyltransferase 2 0.0043 0.0018 0.0116
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0015 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0012 0.0013
Brugia malayi Glutamate receptor 2 precursor 0.016 0.0101 0.0651
Giardia lamblia Hexose transporter 0.0031 0.0009 0.0293
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0144 0.009 0.058
Brugia malayi Matrixin family protein 0.0051 0.0023 0.0151
Brugia malayi Histone deacetylase 1 0.0078 0.0043 0.0277
Echinococcus granulosus dna polymerase kappa 0.004 0.0016 0.0101
Echinococcus granulosus integrin alpha 3 0.0076 0.0041 0.0266
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0846 0.0589 0.3792
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0046 0.002 0.0019
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0038 0.0244
Toxoplasma gondii kringle domain-containing protein 0.0062 0.0031 0.0514
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0036 0.1755
Brugia malayi Histone deacetylase family protein 0.0071 0.0038 0.0242
Trypanosoma brucei N-myristoyltransferase 0.0043 0.0018 0.0203
Brugia malayi Furin-like cysteine rich region family protein 0.0144 0.009 0.0577
Toxoplasma gondii sugar transporter ST1 0.0031 0.0009 0.0145
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0085 0.0048 0.0306
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Brugia malayi mbt repeat family protein 0.0066 0.0034 0.022
Schistosoma mansoni glucose transport protein 0.022 0.0144 0.0165
Schistosoma mansoni amine GPCR 0.1214 0.0851 0.0974
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0009 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0066 0.0034 0.0039
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0009 0.006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0004 0.0003
Toxoplasma gondii aminopeptidase n, putative 0.0862 0.0601 1
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Trypanosoma brucei cytochrome P450, putative 0.0147 0.0092 0.1047
Brugia malayi nuclear hormone receptor 0.0019 0 0.0003
Schistosoma mansoni hypothetical protein 0.0031 0.001 0.0011
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Echinococcus granulosus alpha 1A adrenergic receptor 0.1214 0.0851 0.549
Plasmodium falciparum histone deacetylase, putative 0.0071 0.0038 0.0616
Brugia malayi Pre-SET motif family protein 0.0034 0.0012 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0373 0.0253 0.1629
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0846 0.0589 0.3798
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Schistosoma mansoni integrin alpha-ps 0.0023 0.0004 0.0004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0206 0.0134 0.4249
Echinococcus granulosus tissue type plasminogen activator 0.0062 0.0031 0.0202
Echinococcus granulosus tm gpcr rhodopsin 0.1214 0.0851 0.549
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0373 0.0253 0.1629
Schistosoma mansoni myosin xvIII 0.1214 0.0851 0.0974
Brugia malayi Latrophilin receptor protein 2 0.0056 0.0027 0.0176
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0176
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0 0.0003
Echinococcus granulosus g protein coupled receptor 0.1214 0.0851 0.549
Onchocerca volvulus 0.0031 0.0009 0.0057
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0016 0.0173
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus g-protein coupled receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0 0.0003
Onchocerca volvulus 0.0031 0.0009 0.0057
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0127 0.0078 0.0077
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0373 0.0253 0.1629
Brugia malayi histone deacetylase 1 (HD1) 0.0078 0.0043 0.0277
Echinococcus multilocularis leucine aminopeptidase protein 0.0541 0.0373 0.2403
Leishmania major hypothetical protein, conserved 0.005 0.0023 0.0258
Mycobacterium ulcerans acyl-CoA synthetase 0.004 0.0016 0.0014
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0038 0.1189
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0127 0.0078 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0009 0.0434
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0461 0.0315 0.0361
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0 0.0003
Leishmania major histone deacetylase, putative 0.0071 0.0038 0.0424
Plasmodium vivax hypothetical protein, conserved 0.0031 0.001 0.0151
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.004 0.0016 0.0014
Echinococcus granulosus nmda type glutamate receptor 0.0181 0.0116 0.0747
Onchocerca volvulus 0.0062 0.0031 0.02
Onchocerca volvulus 0.0019 0.0001 0.0001
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0383 0.026 0.1673
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0665 0.046 0.2964
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0354 0.0239 0.1542
Toxoplasma gondii Na+/H+ exchanger NHE1 0.005 0.0023 0.0375
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14, putative 0.0076 0.0041 0.0465
Echinococcus multilocularis histone acetyltransferase MYST2 0.0075 0.0041 0.0262
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Leishmania major DNA polymerase eta, putative 0.003 0.0009 0.0091
Onchocerca volvulus 0.0076 0.0041 0.0262
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0425 0.029 0.3313
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0045 0.002 0.0018
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.0043 0.2118
Schistosoma mansoni hypothetical protein 0.0056 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0053 0.0025 0.0159
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.002 0.0611
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0846 0.0589 0.3791
Echinococcus granulosus neuropeptide Y receptor 0.1214 0.0851 0.549
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0144 0.009 0.0103
Echinococcus multilocularis 0.0044 0.0019 0.012
Loa Loa (eye worm) G-protein coupled receptor 0.1214 0.0851 0.5481
Loa Loa (eye worm) glutathione reductase 0.0069 0.0036 0.0234
Plasmodium vivax hypothetical protein, conserved 0.0373 0.0253 0.4199
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.000005704 0.0000065289
Echinococcus multilocularis glutamate receptor NMDA 0.016 0.0101 0.065
Brugia malayi hypothetical protein 0.0031 0.0009 0.0059
Plasmodium vivax histone deacetylase 2, putative 0.0071 0.0038 0.0616
Schistosoma mansoni thyroid hormone receptor 0.0019 0 0.0001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.1214 0.0851 0.5481
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0006 0.0007
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1214 0.0851 0.0974
Entamoeba histolytica histone deacetylase, putative 0.0078 0.0043 0.1353
Brugia malayi jmjC domain containing protein 0.0023 0.0003 0.0022
Echinococcus multilocularis Squalene phytoene synthase 0.0388 0.0263 0.1698
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0 0.0001
Trypanosoma cruzi histone deacetylase, putative 0.0034 0.0011 0.0123
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Leishmania major trypanothione reductase 0.0069 0.0036 0.041
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0009 0.0059
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0 0.0003
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0264 0.0175 0.1128
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.0003 0.0033
Plasmodium falciparum amino acid transporter, putative 0.0373 0.0253 0.4199
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0023 0.0003 0.0021
Echinococcus multilocularis sex peptide receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) hypothetical protein 0.0059 0.0029 0.0187
Echinococcus granulosus dnaJ subfamily B 0.0327 0.022 0.142
Plasmodium vivax aspartyl protease, putative 0.0023 0.0003 0.0045
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0004 0.0062
Schistosoma mansoni sugar transporter 0.0031 0.0009 0.0011
Echinococcus granulosus peptide allatostatin:somatostatin 0.1214 0.0851 0.549
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0038 0.0429
Echinococcus granulosus glycine receptor subunit alpha 1 0.0846 0.0589 0.3798
Echinococcus granulosus nmda type glutamate receptor 0.0254 0.0168 0.1084
Plasmodium falciparum histone deacetylase 2 0.0071 0.0038 0.0616
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0249 0.0165 0.1061
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0019 0.0001 0.0003
Mycobacterium leprae probable conserved integral membrane transport protein 0.005 0.0023 0.0022
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0862 0.0601 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Schistosoma mansoni glucose transporter 0.0031 0.0009 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0024 0.0004 0.012
Echinococcus granulosus receptor type guanylyl cyclase 0.0023 0.0004 0.0025
Brugia malayi histone deacetylase 3 (HD3) 0.0078 0.0043 0.0277
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0038 0.0043
Plasmodium vivax histone deacetylase 1, putative 0.0078 0.0043 0.0709
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.054
Echinococcus multilocularis glycine receptor subunit beta 0.0846 0.0589 0.3798
Toxoplasma gondii sodium/hydrogen exchanger 3 protein 0.005 0.0023 0.0375
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Loa Loa (eye worm) glutamate receptor 1 0.016 0.0101 0.0651
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0394 0.0268 0.1725
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Onchocerca volvulus 0.0031 0.0009 0.0057
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0085 0.0048 0.0306
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Loa Loa (eye worm) MBOAT family protein 0.0019 0.0001 0.0003
Onchocerca volvulus 0.1214 0.0851 0.5489
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0012 0.0134
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Trypanosoma brucei unspecified product 0.0035 0.0012 0.0134
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Loa Loa (eye worm) hypothetical protein 0.0034 0.0011 0.0072
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trypanosoma brucei glucosidase, putative 0.0024 0.0004 0.0045
Plasmodium falciparum plasmepsin IV 0.0057 0.0028 0.0456
Schistosoma mansoni amine GPCR 0.1214 0.0851 0.0974
Brugia malayi phosphofructokinase 0.0131 0.0081 0.0519
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0037 0.0014 0.009
Brugia malayi MBOAT family protein 0.0019 0.0001 0.0003
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.004 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.003 0.0009 0.001
Brugia malayi Stress-activated protein kinase jnk-1 0.0104 0.0061 0.0394
Echinococcus multilocularis epidermal growth factor receptor 0.0078 0.0043 0.0276
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus sodium:hydrogen exchanger 0.0264 0.0175 0.1128
Schistosoma mansoni myelin transcription factor 1 myt1 0.0075 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0005 0.0033
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14, putative 0.0076 0.0041 0.0465
Schistosoma mansoni glutamate receptor NMDA 0.0354 0.0239 0.0274
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0388 0.0263 0.1695
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0144 0.009 0.058
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0013 0.0595
Echinococcus multilocularis histone deacetylase 6 0.0071 0.0038 0.0242
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.003 0.0009 0.0115
Plasmodium falciparum plasmepsin X 0.0023 0.0003 0.0045
Leishmania major histone deacetylase, putative 0.0071 0.0038 0.0424
Echinococcus multilocularis GPCR, family 2 0.0056 0.0027 0.0176
Treponema pallidum bacterioferrin (TpF1) 0.002 0.0001 0.0004
Schistosoma mansoni neurotransmitter gated ion channel 0.0461 0.0315 0.0361
Schistosoma mansoni amine GPCR 0.1214 0.0851 0.0974
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0016 0.0173
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.1214 0.0851 0.0974
Onchocerca volvulus 0.1214 0.0851 0.5489
Echinococcus granulosus insulin receptor 0.0047 0.0021 0.0133
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.1214 0.0851 0.549
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Loa Loa (eye worm) hypothetical protein 0.0264 0.0175 0.1126
Echinococcus granulosus epidermal growth factor receptor 0.0144 0.009 0.0578
Schistosoma mansoni ferritin light chain 0.002 0.0001 0.0001
Brugia malayi Sugar transporter family protein 0.022 0.0144 0.0925
Trypanosoma cruzi hexose transporter 0.0068 0.0036 0.0404
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.003 0.0009 0.0057
Echinococcus multilocularis integrin alpha ps 0.0044 0.0019 0.0122
Schistosoma mansoni biogenic amine (5HT) receptor 0.1214 0.0851 0.0974
Loa Loa (eye worm) hypothetical protein 0.0231 0.0152 0.0978
Schistosoma mansoni protein kinase 0.004 0.0016 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0846 0.0589 0.3792
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0461 0.0315 0.0361
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.005 0.0023 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0 0.0003
Loa Loa (eye worm) zinc carboxypeptidase 0.0076 0.0041 0.0264
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.1214 0.0851 0.5481
Echinococcus granulosus glutamate receptor 2 0.0181 0.0116 0.0748
Echinococcus granulosus L aminoadipate semialdehyde 0.0059 0.0029 0.0187
Loa Loa (eye worm) integrin beta-2 0.0203 0.0132 0.0848
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0 0.0003
Loa Loa (eye worm) mbt repeat family protein 0.0066 0.0034 0.022
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0144 0.009 0.1026
Schistosoma mansoni peptidase 0.0076 0.0041 0.0047
Schistosoma mansoni histone deacetylase 4 5 0.0071 0.0038 0.0043
Loa Loa (eye worm) hypothetical protein 0.0075 0.0041 0.0261
Echinococcus multilocularis neuropeptide receptor A26 0.1582 0.1113 0.7179
Leishmania major DNA polymerase kappa, putative 0.0024 0.0005 0.0046
Echinococcus multilocularis Protein lozenge 0.0023 0.0004 0.0024
Schistosoma mansoni cathepsin D (A01 family) 0.0145 0.0091 0.0104
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0004 0.0043
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0004 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0083 0.0047 0.0053
Onchocerca volvulus 0.0441 0.0301 0.1939
Onchocerca volvulus 0.0023 0.0003 0.0018
Brugia malayi MBOAT family protein 0.0019 0.0001 0.0003
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0461 0.0315 0.2028
Echinococcus granulosus sex peptide receptor 0.1214 0.0851 0.549
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0007 0.0006
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.4199
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.0043 0.2118
Schistosoma mansoni coup transcription factor 0.0019 0 0.0001
Echinococcus granulosus FTZ F1 alpha 0.0019 0 0.0003
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0519 0.0356 0.4082
Mycobacterium ulcerans polyketide synthase Pks9 0.0037 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0035
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0077 0.0042 0.0269
Brugia malayi prolyl oligopeptidase family protein 0.0049 0.0022 0.0143
Schistosoma mansoni histone deacetylase 4 5 0.0071 0.0038 0.0043
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0846 0.0589 0.3792
Schistosoma mansoni glucose transport protein 0.022 0.0144 0.0165
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0665 0.046 0.0527
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0846 0.0589 0.3792
Plasmodium falciparum plasmepsin IX 0.0023 0.0003 0.0045
Loa Loa (eye worm) ACC-1 protein 0.0846 0.0589 0.3791
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Toxoplasma gondii histone deacetylase HDAC4 0.0034 0.0011 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.004 0.0016 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0056 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.1214 0.0851 0.549
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0014 0.0152
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0036 0.0406
Schistosoma mansoni nuclear hormone receptor 0.0019 0 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0541 0.0373 0.0371
Onchocerca volvulus 0.0373 0.0253 0.1627
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0024 0.0004 0.0028
Onchocerca volvulus Putative transporter 0.0031 0.0009 0.0057
Mycobacterium ulcerans histidinol dehydrogenase 1.4071 1 1
Onchocerca volvulus 0.0846 0.0589 0.3796
Echinococcus granulosus solute carrier family 22 0.0031 0.0009 0.0059
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0076 0.0041 0.0465
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.0021 0.0133
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0083 0.0047 0.0053
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.054
Trypanosoma cruzi PAB1-binding protein , putative 0.0037 0.0014 0.0148
Loa Loa (eye worm) hypothetical protein 0.0157 0.0099 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0009 0.0434
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0036 0.0404
Brugia malayi Bromodomain containing protein 0.0041 0.0017 0.0107
Loa Loa (eye worm) steroid hormone receptor 0.0019 0 0.0003
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0385 0.0261 0.1684
Echinococcus granulosus tm gpcr rhodopsin 0.1214 0.0851 0.549
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0 0.0003
Schistosoma mansoni hypothetical protein 0.0332 0.0224 0.0256
Echinococcus multilocularis integrin alpha ps 0.0021 0.0002 0.0015
Leishmania major extracellular receptor, putative 0.0021 0.0002 0.002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0175 0.0112 0.0111
Plasmodium vivax glutathione reductase, putative 0.0069 0.0036 0.0596
Mycobacterium ulcerans membrane transporter 0.005 0.0023 0.0022
Trypanosoma brucei aminopeptidase, putative 0.0144 0.009 0.1028
Onchocerca volvulus 0.0385 0.0261 0.1682
Brugia malayi hypothetical protein 0.0021 0.0002 0.0014
Brugia malayi sulfakinin receptor protein 0.2201 0.1553 1
Loa Loa (eye worm) hhat protein 0.0019 0.0001 0.0003
Trypanosoma brucei glucose transporter, putative 0.0068 0.0036 0.0406
Echinococcus granulosus atrial natriuretic peptide receptor 0.0021 0.0002 0.0014
Chlamydia trachomatis cytosol aminopeptidase 0.0541 0.0373 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.009 0.0051 0.0058
Onchocerca volvulus 0.1214 0.0851 0.5489
Onchocerca volvulus 0.004 0.0016 0.0099
Echinococcus multilocularis serotonin receptor 0.1214 0.0851 0.549
Echinococcus granulosus ubiquitin specific protease 41 0.003 0.0009 0.0057
Schistosoma mansoni cpg binding protein 0.0043 0.0018 0.0021
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0846 0.0589 0.0674
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0264 0.0175 0.1126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Onchocerca volvulus 0.0031 0.0009 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0033 0.0215
Schistosoma mansoni phosphatidylserine receptor 0.0023 0.0003 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0846 0.0589 0.3798
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Schistosoma mansoni neuropeptide receptor 0.1214 0.0851 0.0974
Trichomonas vaginalis alpha-glucosidase, putative 0.0024 0.0004 0.0187
Brugia malayi Melatonin receptor type 1A 0.1214 0.0851 0.5481
Onchocerca volvulus 0.1214 0.0851 0.5489
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Loa Loa (eye worm) glutaminase 2 0.0301 0.0201 0.1296
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0385 0.0261 0.1684
Schistosoma mansoni hypothetical protein 0.1214 0.0851 0.0974
Brugia malayi Dopamine receptor protein 1 0.1214 0.0851 0.5481
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0144 0.009 0.1026
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.2107 0.1486 0.9569
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0005 0.0049
Loa Loa (eye worm) histone deacetylase 0.0071 0.0038 0.0241
Loa Loa (eye worm) hypothetical protein 0.0144 0.009 0.0579
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0016 0.0751
Schistosoma mansoni hypothetical protein 0.0066 0.0034 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.004 0.0016 0.0014
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0264 0.0175 0.1126
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Loa Loa (eye worm) hypothetical protein 0.2197 0.1551 0.9983
Toxoplasma gondii aminopeptidase N, putative 0.0862 0.0601 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0846 0.0589 0.3798
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0846 0.0589 0.3792
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0018 0.0117
Echinococcus granulosus biogenic amine 5HT receptor 0.1214 0.0851 0.549
Trichomonas vaginalis ferritin, putative 0.002 0.0001 0.0034
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0066 0.0034 0.0221
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.0021 0.0133
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.011 0.545
Loa Loa (eye worm) hypothetical protein 0.0144 0.009 0.0579
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0127 0.0078 0.0077
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.2107 0.1486 0.9585
Plasmodium falciparum ataxin-2 like protein, putative 0.0037 0.0014 0.0216
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0117 0.007 0.0802
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Toxoplasma gondii histone lysine methyltransferase SET1 0.0087 0.0049 0.0809
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.0021 0.0129
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0373 0.0253 0.0289
Echinococcus multilocularis solute carrier family 22 0.0031 0.0009 0.0059
Echinococcus multilocularis dro:myosuppressin receptor 0.1214 0.0851 0.549
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0057 0.0028 0.018
Echinococcus granulosus integrin alpha ps 0.0021 0.0002 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0 0.0003
Schistosoma mansoni cpg binding protein 0.0048 0.0021 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.1214 0.0851 0.549
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0057 0.0028 0.0179
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0165 0.8178
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.1626
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0127 0.0078 0.0077
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0264 0.0175 0.1128
Schistosoma mansoni metallocarboxypeptidase D peptidase unit 2 (M14 family) 0.0076 0.0041 0.0047
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0001 0.0005
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0373 0.0253 0.1629
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0007 0.0006
Onchocerca volvulus 0.0846 0.0589 0.3796
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.1214 0.0851 0.549
Echinococcus granulosus leukotriene A 4 hydrolase 0.0665 0.046 0.2969
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.1214 0.0851 0.0974
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0062 0.0031 0.0514
Leishmania major hypothetical protein, conserved 0.0037 0.0014 0.0148
Echinococcus granulosus cytosolic carboxypeptidase 1 0.0076 0.0041 0.0265
Loa Loa (eye worm) hypothetical protein 0.0184 0.0118 0.0762
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.011 0.0065 0.042
Trichomonas vaginalis N-myristoyl transferase, putative 0.0043 0.0018 0.0871
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Echinococcus multilocularis subfamily M14A unassigned peptidase 0.0441 0.0301 0.1941
Echinococcus granulosus serotonin receptor 0.1214 0.0851 0.549
Echinococcus granulosus glycine receptor subunit alpha 1 0.0846 0.0589 0.3798
Schistosoma mansoni biogenic amine receptor 0.1214 0.0851 0.0974
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Loa Loa (eye worm) histone deacetylase 1 0.0078 0.0043 0.0277
Echinococcus granulosus orexin receptor type 2 0.1214 0.0851 0.549
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0087 0.0049 0.0317
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.0538
Plasmodium falciparum acyl-CoA synthetase 0.003 0.0009 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0096
Toxoplasma gondii aspartyl protease ASP1 0.0057 0.0028 0.0456
Echinococcus granulosus g protein coupled receptor 0.1214 0.0851 0.549
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0 0.0003
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0016 0.0014
Brugia malayi Cytochrome P450 family protein 0.0144 0.009 0.0577
Trichomonas vaginalis conserved hypothetical protein 0.022 0.0144 0.7131
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0127 0.0078 0.0887
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0137 0.0084 0.0545
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0057 0.0028 0.0456
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Plasmodium falciparum glycylpeptide N-tetradecanoyltransferase 0.0043 0.0018 0.0291
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0846 0.0589 0.3798
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0006 0.0035
Echinococcus multilocularis sodium:hydrogen exchanger 0.0264 0.0175 0.1128
Trypanosoma cruzi DNA polymerase eta, putative 0.003 0.0009 0.0091
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trypanosoma cruzi trypanothione reductase, putative 0.0069 0.0036 0.041
Loa Loa (eye worm) hypothetical protein 0.0173 0.011 0.0708
Entamoeba histolytica hypothetical protein 0.0043 0.0018 0.056
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1214 0.0851 0.549
Schistosoma mansoni hypothetical protein 0.0043 0.0018 0.0021
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0373 0.0253 0.1629
Brugia malayi putative neuropeptide receptor NPR1 0.1214 0.0851 0.5481
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0021 0.0002 0.0014
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0055
Schistosoma mansoni tyrosine kinase 0.0023 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0062 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0 0.0003
Onchocerca volvulus 0.1214 0.0851 0.5489
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0127 0.0078 0.0077
Giardia lamblia DINP protein human, muc B family 0.0024 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0081 0.2547
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0385 0.0261 0.1684
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0065 0.0033 0.0213
Echinococcus granulosus General substrate transporter 0.0189 0.0122 0.0785
Schistosoma mansoni hypothetical protein 0.1214 0.0851 0.0974
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Schistosoma mansoni memapsin-2 (A01 family) 0.0163 0.0104 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.003 0.0009 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1214 0.0851 0.0974
Brugia malayi hypothetical protein 0.0281 0.0187 0.1205
Schistosoma mansoni glutamate receptor kainate 0.016 0.0101 0.0116
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0076 0.0041 0.216
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0004 0.0062
Onchocerca volvulus 0.0031 0.0009 0.0057
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.01 0.0058 0.0663
Toxoplasma gondii LsmAD domain-containing protein 0.0037 0.0014 0.0216
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0264 0.0175 0.1128
Plasmodium falciparum phd finger protein, putative 0.0031 0.001 0.0151
Loa Loa (eye worm) histone deacetylase 3 0.0078 0.0043 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0061 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1871 0.1318 0.8503
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0066 0.0034 0.0221
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0016 0.0175
Schistosoma mansoni protein kinase 0.0023 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Toxoplasma gondii type I fatty acid synthase, putative 0.004 0.0016 0.0255
Echinococcus granulosus sodium and chloride dependent glycine 0.0373 0.0253 0.1629
Echinococcus multilocularis polycomb protein SCMH1 0.0066 0.0034 0.022
Giardia lamblia PHD finger protein 15 0.0031 0.001 0.0315
Mycobacterium ulcerans potassium/proton antiporter 0.005 0.0023 0.0022
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.1214 0.0851 0.549
Brugia malayi putative neuropeptide receptor 0.1214 0.0851 0.5481
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0127 0.0078 0.0077
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0181 0.0116 0.0748
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0101 0.0059 0.0058
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1214 0.0851 0.0974
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0001 0.0006
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0001 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0165 0.8178
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.0081 0.052
Echinococcus multilocularis allatostatin A receptor 0.1214 0.0851 0.549
Mycobacterium ulcerans glutaminase 0.0301 0.0201 0.02
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Brugia malayi glutathione reductase 0.0069 0.0036 0.0234
Brugia malayi mbt repeat family protein 0.0066 0.0034 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Onchocerca volvulus 0.0034 0.0012 0.0073
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0373 0.0253 0.0289
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0137 0.0084 0.0962
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0385 0.0261 0.1681
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0013 0.0199
Brugia malayi Sodium:neurotransmitter symporter family protein 0.2197 0.1551 0.9983
Brugia malayi hypothetical protein 0.0023 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Schistosoma mansoni amine GPCR 1.2296 0.8736 1
Brugia malayi hypothetical protein 0.0037 0.0014 0.0087
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0009 0.0145
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0017 0.0107
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Brugia malayi aspartic protease BmAsp-1, identical 0.0023 0.0003 0.0021
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0144 0.009 0.1026
Echinococcus granulosus polycomb protein SCMH1 0.0066 0.0034 0.022
Brugia malayi Histone deacetylase family protein 0.0071 0.0038 0.0242
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Toxoplasma gondii Na+/H+ exchanger NHE3 0.005 0.0023 0.0375
Echinococcus granulosus expressed protein 0.0339 0.0228 0.1472
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.0149 0.0956
Trypanosoma cruzi histone deacetylase 1, putative 0.0078 0.0043 0.0488
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0004 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0009 0.0098
Onchocerca volvulus Cytosolic carboxypeptidase 1 homolog 0.0076 0.0041 0.0262
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0263 0.0174 0.1123
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.1626
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0076 0.0041 0.216
Schistosoma mansoni opsin-like receptor 0.1214 0.0851 0.0974
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0004 0.0062
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.003 0.0009 0.0057
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0081 0.2547
Loa Loa (eye worm) hhat protein 0.0019 0.0001 0.0003
Schistosoma mansoni tyrosine kinase 0.0047 0.0021 0.0024
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0049 0.0022 0.0143
Echinococcus multilocularis histone deacetylase 3 0.0078 0.0043 0.0278
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0846 0.0589 0.3792
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0385 0.0261 0.1681
Brugia malayi major facilitator superfamily protein 0.0031 0.0009 0.006
Onchocerca volvulus 0.1214 0.0851 0.5489
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0083 0.0047 0.0301
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.005 0.0023 0.0026
Brugia malayi hypothetical protein 0.0147 0.0092 0.0591
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0127 0.0078 0.0077
Schistosoma mansoni tyrosine kinase 0.0076 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0264 0.0175 0.1126
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0019 0.0001 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0037 0.0014 0.0216
Loa Loa (eye worm) MBCTL1 0.0075 0.0041 0.0261
Schistosoma mansoni hypothetical protein 0.1214 0.0851 0.0974
Loa Loa (eye worm) sodium-hydrogen exchanger NHE1 0.005 0.0023 0.0148
Toxoplasma gondii histone deacetylase HDAC2 0.0078 0.0043 0.0709
Schistosoma mansoni histone deacetylase 0.0078 0.0043 0.0049
Echinococcus multilocularis integrin beta 2 0.015 0.0094 0.0608
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0007 0.0043
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.01 0.0058 0.0663
Onchocerca volvulus 0.0076 0.0041 0.0262
Onchocerca volvulus 0.0441 0.0301 0.1939
Schistosoma mansoni sodium-dependent amino acid transporter 0.0373 0.0253 0.0289
Plasmodium vivax amine transporter, putative 0.0373 0.0253 0.4199
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0181 0.0116 0.0748
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1214 0.0851 0.0974
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0181 0.0116 0.0748
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.0076 0.0041 0.0467
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0023 0.0003 0.0048
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0157 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0 0.0001
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0264 0.0175 0.1125
Loa Loa (eye worm) zinc carboxypeptidase 0.0076 0.0041 0.0264
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0024 0.0004 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0425 0.029 0.3313
Onchocerca volvulus 0.1214 0.0851 0.5489
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0004 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Brugia malayi Glycosyl hydrolases family 31 protein 0.0024 0.0004 0.0028
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.1214 0.0851 0.549
Echinococcus granulosus lysosomal alpha glucosidase 0.0108 0.0064 0.0413
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0055
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0127 0.0078 0.0077
Echinococcus granulosus neuropeptide receptor 0.1214 0.0851 0.549
Schistosoma mansoni sodium/hydrogen exchanger 3 (nhe3) 0.005 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0036 0.0406
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0846 0.0589 0.3792
Trypanosoma brucei squalene synthase, putative 0.1244 0.0873 1
Schistosoma mansoni SET domain protein 0.0037 0.0014 0.0016
Trypanosoma brucei Carboxypeptidase-like protein 0.0076 0.0041 0.0467
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1214 0.0851 0.549
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0009 0.0008
Echinococcus granulosus neuropeptide receptor 0.1214 0.0851 0.549
Schistosoma mansoni hypothetical protein 0.0021 0.0002 0.0003
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.001 0.0106
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.0104 0.0666
Onchocerca volvulus 0.0043 0.0018 0.0114
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0004 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Brugia malayi hypothetical protein 0.0157 0.0099 0.0637
Loa Loa (eye worm) hypothetical protein 0.0276 0.0184 0.1183
Brugia malayi hypothetical protein 0.0043 0.0018 0.0117
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0024 0.0005 0.0004
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.1214 0.0851 0.5481
Brugia malayi hypothetical protein 0.0144 0.009 0.058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.0043 0.2118
Onchocerca volvulus 0.0065 0.0033 0.0211
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0004 0.0045
Brugia malayi TATA binding protein associated factor 0.0144 0.009 0.058
Mycobacterium tuberculosis Polyketide synthase Pks12 0.006 0.003 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0024 0.0004 0.0187
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0083 0.0047 0.0301
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0031 0.0009 0.0059
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Toxoplasma gondii histone deacetylase HDAC3 0.0078 0.0043 0.0709
Echinococcus multilocularis glutamate receptor 2 0.0181 0.0116 0.0748
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Trypanosoma cruzi extracellular receptor, putative 0.0021 0.0002 0.002
Schistosoma mansoni acetylcholine receptor subunit beta 0.0385 0.0261 0.0299
Echinococcus multilocularis Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0036 0.1755
Onchocerca volvulus 0.1214 0.0851 0.5489
Giardia lamblia Sodium/hydrogen exchanger 3 0.0264 0.0175 1
Schistosoma mansoni biogenic amine receptor 0.1214 0.0851 0.0974
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0013 0.0223
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1214 0.0851 0.549
Mycobacterium ulcerans aldehyde dehydrogenase 0.0117 0.007 0.0069
Echinococcus multilocularis histone deacetylase 0.0071 0.0038 0.0242
Echinococcus multilocularis phd:f box containing protein 0.0023 0.0003 0.0022
Trypanosoma brucei DNA polymerase eta, putative 0.003 0.0009 0.0093
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.003 0.0009 0.0266
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0541 0.0373 0.0372
Toxoplasma gondii sodium/hydrogen exchanger NHE2 0.005 0.0023 0.0375
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0127 0.0078 0.0077
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0144 0.009 0.1026
Brugia malayi Cytochrome P450 family protein 0.0147 0.0092 0.059
Schistosoma mansoni neuropeptide receptor 0.1214 0.0851 0.0974
Schistosoma mansoni thyroid hormone receptor 0.0019 0 0.0001
Leishmania major histone deacetylase, putative 0.0078 0.0043 0.0488
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0281 0.0187 0.9296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.004
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.0076 0.0041 0.0467
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0127 0.0078 0.0077
Loa Loa (eye worm) G-protein coupled receptor 0.1214 0.0851 0.5481
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.0538
Brugia malayi Pepsin A precursor 0.0023 0.0003 0.0021
Loa Loa (eye worm) glutamate receptor 0.0021 0.0002 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.1214 0.0851 0.0974
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0846 0.0589 0.3792
Loa Loa (eye worm) hypothetical protein 0.0066 0.0034 0.022
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0461 0.0315 0.2028
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0552 0.038 0.0435
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.003 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0055
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0264 0.0175 0.1125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1214 0.0851 0.0974
Brugia malayi hypothetical protein 0.0373 0.0253 0.1626
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0018 0.0021
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0117 0.007 0.0454
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0264 0.0175 0.1128
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Onchocerca volvulus Huntingtin homolog 0.0157 0.0099 0.0635
Echinococcus granulosus fmrfamide receptor 0.1214 0.0851 0.549
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.1214 0.0851 0.5489
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0264 0.0175 0.1128
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.2107 0.1486 0.9585
Echinococcus granulosus glutamate receptor subunit protein glur 0.0066 0.0034 0.0221
Brugia malayi Cation transporter family protein 0.0846 0.0589 0.3792
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Brugia malayi Cation transporter family protein 0.0846 0.0589 0.3792
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.001 0.0062
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.0076 0.0041 0.0676
Mycobacterium ulcerans phytoene synthase, CrtB 0.0388 0.0263 0.0262
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1214 0.0851 0.0974
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.0076 0.0041 0.0676
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0373 0.0253 0.4199
Echinococcus multilocularis expressed protein 0.002 0.0001 0.0008
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0101 0.0059 0.0058
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Schistosoma mansoni peptidase 0.0076 0.0041 0.0047
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.006 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0127 0.0078 0.0077
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0264 0.0175 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0009 0.0434
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Treponema pallidum NADH oxidase 0.0024 0.0004 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0003
Plasmodium falciparum plasmepsin VII 0.0023 0.0003 0.0045
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0017 0.0107
Loa Loa (eye worm) hypothetical protein 0.0078 0.0043 0.0277
Echinococcus granulosus nAChR subunit 0.0461 0.0315 0.2031
Echinococcus multilocularis rho associated protein kinase 0.0044 0.0019 0.0119
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0087
Onchocerca volvulus 0.0062 0.0032 0.0202
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.0043 0.2118
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0373 0.0253 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0 0.0003
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0846 0.0589 0.0674
Brugia malayi Peptidase family M1 containing protein 0.0281 0.0187 0.1205
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0013 0.0595
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0085 0.0048 0.0306
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0066 0.0034 0.0221
Echinococcus granulosus neutral alpha glucosidase AB 0.0024 0.0004 0.0028
Mycobacterium ulcerans aminopeptidase N PepN 0.0144 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0025
Schistosoma mansoni tyrosine kinase 0.0047 0.0021 0.0024
Echinococcus multilocularis histone deacetylase 1 0.0078 0.0043 0.0278
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0004 0.0043
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.0081 0.0918
Onchocerca volvulus Histone deacetylase 10 homolog 0.0034 0.0011 0.007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0083 0.0047 0.0053
Loa Loa (eye worm) GABA receptor subunit 0.0461 0.0315 0.2028
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0085 0.0048 0.0054
Trypanosoma cruzi histone deacetylase, putative 0.0071 0.0038 0.0424
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0049 0.0022 0.0143
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0056 0.0027 0.0177
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0083 0.0047 0.0301
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Echinococcus granulosus solute carrier family 22 0.0031 0.0009 0.0059
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0055 0.0026 0.0025
Echinococcus multilocularis neutral alpha glucosidase AB 0.0024 0.0004 0.0028
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0016 0.0751
Loa Loa (eye worm) CXXC zinc finger family protein 0.0043 0.0018 0.0116
Brugia malayi steroid hormone receptor 0.0019 0 0.0003
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0018 0.0118
Schistosoma mansoni hypothetical protein 0.0076 0.0041 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0127 0.0078 0.0077
Loa Loa (eye worm) sugar transporter 0.022 0.0144 0.0925
Onchocerca volvulus 0.0031 0.0009 0.0057
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0081 0.0918
Toxoplasma gondii aspartyl protease 0.0023 0.0003 0.0045
Schistosoma mansoni sodium/hydrogen exchanger 0.0264 0.0175 0.02
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0063
Plasmodium vivax histone deacetylase, putative 0.0071 0.0038 0.0616
Brugia malayi hypothetical protein 0.0385 0.0261 0.1681
Loa Loa (eye worm) LGC-31 protein 0.0846 0.0589 0.3791
Onchocerca volvulus 0.0461 0.0315 0.2029
Echinococcus granulosus solute carrier family 22 0.0031 0.0009 0.0059
Treponema pallidum fructose-bisphosphate aldolase 0.0206 0.0134 0.0862
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Plasmodium vivax hexose transporter 0.022 0.0144 0.2385
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0009 0.0008
Loa Loa (eye worm) integrin alpha pat-2 0.0153 0.0096 0.0618
Plasmodium vivax sodium/hydrogen exchanger 1, putative 0.005 0.0023 0.0375
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0037 0.0014 0.0013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0461 0.0315 0.2028
Loa Loa (eye worm) cytochrome P450 0.0127 0.0078 0.0502
Plasmodium falciparum hexose transporter 0.022 0.0144 0.2385
Trichomonas vaginalis sucrase-isomaltase, putative 0.0024 0.0004 0.0187
Toxoplasma gondii aminopeptidase N protein 0.0862 0.0601 1
Echinococcus granulosus sterol O acyltransferase 1 0.0191 0.0123 0.0795
Echinococcus multilocularis fmrfamide receptor 0.1214 0.0851 0.549
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni opsin-like receptor 0.1214 0.0851 0.0974
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0015 0.0096
Brugia malayi Guanylyl cyclase protein 23 0.0023 0.0004 0.0025
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0127 0.0078 0.0077
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0127 0.0078 0.0077
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0175 0.0112 0.0111
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0 0.0003
Echinococcus granulosus sodium:hydrogen exchanger 0.0264 0.0175 0.1128
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Echinococcus multilocularis histone deacetylase 7 0.0071 0.0038 0.0242
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Onchocerca volvulus 0.0031 0.0009 0.0057
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0846 0.0589 0.3792
Brugia malayi Metabotropic glutamate receptor precursor. 0.0021 0.0002 0.0014
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0007 0.0043
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0056 0.0027 0.0176
Plasmodium vivax thioredoxin reductase, putative 0.0069 0.0036 0.0596
Trypanosoma brucei N-myristoyl transferase, putative 0.0043 0.0018 0.0203
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0041 0.0016 0.0015
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0004 0.0062
Leishmania major 4-coumarate:coa ligase-like protein 0.004 0.0016 0.0174
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0846 0.0589 0.3798
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.0081 0.0079
Loa Loa (eye worm) TYRA-2 protein 0.1214 0.0851 0.5481
Echinococcus multilocularis G-protein coupled receptor, putative 0.1214 0.0851 0.549
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Echinococcus granulosus serotonin transporter 0.2197 0.1551 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0107 0.0063 0.0408
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0094 0.0054 0.0062
Loa Loa (eye worm) cytochrome P450 family protein 0.0147 0.0092 0.059
Mycobacterium ulcerans thioesterase TesA 0.0047 0.0021 0.002
Echinococcus granulosus integrin alpha ps 0.0044 0.0019 0.0122
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1474 0.1036 0.6673
Mycobacterium ulcerans polyketide synthase 0.0056 0.0027 0.0026
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0008 0.0051
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0373 0.0253 0.1629
Echinococcus granulosus thioredoxin glutathione reductase 0.0069 0.0037 0.0236
Mycobacterium tuberculosis Probable thioesterase TesA 0.0047 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Loa Loa (eye worm) hypothetical protein 0.0048 0.0022 0.014
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0101 0.0059 0.0058
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0009 0.006
Brugia malayi AMP-binding enzyme family protein 0.0065 0.0033 0.0213
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.0144 0.0927
Brugia malayi Serotonin receptor 0.1214 0.0851 0.5481
Schistosoma mansoni sugar transporter 0.0031 0.0009 0.0011
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0 0.0003
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0021 0.0002 0.0014
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0 0.0001
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.029 0.0193 0.0221
Brugia malayi latrophilin 2 splice variant baaae 0.0122 0.0074 0.0476
Schistosoma mansoni family M14 non-peptidase homologue (M14 family) 0.0076 0.0041 0.0047
Echinococcus multilocularis tyrosine protein kinase Abl 0.0161 0.0102 0.0657
Plasmodium falciparum M17 leucyl aminopeptidase 0.0425 0.029 0.4814
Schistosoma mansoni integrin alpha 0.0099 0.0058 0.0066
Echinococcus multilocularis peregrin 0.0044 0.0019 0.0121
Schistosoma mansoni bromodomain containing protein 0.0071 0.0038 0.0043
Mycobacterium tuberculosis Probable reductase 0.0157 0.0099 0.0098
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) phosphofructokinase 0.0131 0.0081 0.0519
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0076 0.0041 0.0465
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0385 0.0261 0.1681
Brugia malayi MBOAT family protein 0.0019 0.0001 0.0003
Brugia malayi hypothetical protein 0.2201 0.1553 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0127 0.0078 0.0889
Loa Loa (eye worm) cytochrome P450 family protein 0.0144 0.009 0.0577
Trypanosoma brucei histone deacetylase, putative 0.0071 0.0038 0.0426
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0009 0.006
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Brugia malayi hypothetical protein 0.0385 0.0261 0.1681
Schistosoma mansoni ATP-binding cassette transporter 0.016 0.0101 0.0116
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.1214 0.0851 0.0974
Schistosoma mansoni amine GPCR 0.1214 0.0851 0.0974
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0065 0.0033 0.0032
Brugia malayi hypothetical protein 0.0031 0.0009 0.006
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0057 0.0028 0.0179
Brugia malayi Peptidase family M1 containing protein 0.0685 0.0475 0.3056
Trichomonas vaginalis set domain proteins, putative 0.0258 0.0171 0.847
Toxoplasma gondii hypothetical protein 0.0373 0.0253 0.4199
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0001 0.0006
Plasmodium vivax ataxin-2 like protein, putative 0.0037 0.0014 0.0216
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0028 0.0007 0.0006
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Loa Loa (eye worm) hypothetical protein 0.0041 0.0017 0.0107
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0003 0.0022
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0036 0.0406
Loa Loa (eye worm) cytochrome P450 family protein 0.0147 0.0092 0.059
Toxoplasma gondii histone deacetylase HDAC5 0.0034 0.0011 0.018
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0016 0.0014
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Onchocerca volvulus 0.0021 0.0002 0.0012
Trypanosoma brucei glucose transporter 1E 0.0068 0.0036 0.0406
Echinococcus granulosus Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Echinococcus multilocularis neuropeptides capa receptor 0.1214 0.0851 0.549
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0084 0.0047 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Echinococcus multilocularis g-protein coupled receptor 0.1214 0.0851 0.549
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1214 0.0851 0.549
Schistosoma mansoni tyrosine kinase 0.0023 0.0004 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0013 0.0595
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0013 0.0077
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0057 0.0028 0.018
Trichomonas vaginalis alpha-glucosidase, putative 0.0024 0.0004 0.0187
Loa Loa (eye worm) aspartyl protease 6 0.0023 0.0003 0.0021
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0013 0.0199
Trypanosoma brucei PAB1-binding protein , putative 0.0037 0.0014 0.0151
Schistosoma mansoni sex comb on midleg homolog 0.0066 0.0034 0.0039
Echinococcus multilocularis sodium and chloride dependent glycine 0.0373 0.0253 0.1629
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Trypanosoma cruzi cytochrome P450, putative 0.0147 0.0092 0.1044
Echinococcus granulosus glutamate receptor NMDA 0.016 0.0101 0.065
Onchocerca volvulus Huntingtin homolog 0.0157 0.0099 0.0635
Echinococcus multilocularis g protein coupled receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.1214 0.0851 0.5481
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0862 0.0601 1
Plasmodium falciparum plasmepsin II 0.0057 0.0028 0.0456
Onchocerca volvulus Neuropeptide F receptor homolog 0.1214 0.0851 0.5489
Echinococcus granulosus peregrin 0.0044 0.0019 0.0121
Schistosoma mansoni protein phosphatase 2C 0.0023 0.0003 0.0004
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.015 0.0094 0.0606
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Entamoeba histolytica hypothetical protein 0.0461 0.0315 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0013 0.0199
Echinococcus granulosus neuropeptides capa receptor 0.1214 0.0851 0.549
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0 0.0003
Echinococcus granulosus tachykinin peptides receptor 99D 0.1214 0.0851 0.549
Echinococcus multilocularis serotonin transporter 0.2197 0.1551 1
Leishmania major 4-coumarate:coa ligase-like protein 0.004 0.0016 0.0174
Echinococcus granulosus solute carrier family 22 0.0031 0.0009 0.0059
Onchocerca volvulus Putative nachr subunit 0.2107 0.1486 0.9585
Schistosoma mansoni ferritin 0.002 0.0001 0.0001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0004 0.0043
Loa Loa (eye worm) histone deacetylase 11 0.0034 0.0011 0.0072
Mycobacterium ulcerans fatty-acid-CoA ligase 0.003 0.0009 0.0007
Onchocerca volvulus 0.2197 0.1551 1
Trypanosoma brucei histone deacetylase 2 0.0034 0.0011 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0004 0.0045
Echinococcus granulosus cytochrome P450 2K1 0.0127 0.0078 0.0502
Brugia malayi Protein kinase domain containing protein 0.0135 0.0084 0.0538
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0004 0.0045
Mycobacterium ulcerans aminopeptidase N PepN 0.0281 0.0187 0.0186
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0078 0.0043 0.0276
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Schistosoma mansoni neuropeptide f receptor 76f 0.1214 0.0851 0.0974
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0007 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.004 0.0016 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0009 0.01
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0009 0.0059
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0009 0.0059
Echinococcus granulosus hypothetical protein 0.1214 0.0851 0.549
Trypanosoma cruzi histone deacetylase, putative 0.0034 0.0011 0.0123
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.015 0.0094 0.0606
Toxoplasma gondii zinc carboxypeptidase, putative 0.0076 0.0041 0.0676
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0009 0.0417
Brugia malayi ORL1-like opioid receptor 0.1214 0.0851 0.5481
Schistosoma mansoni sterol O-acyltransferase 1 0.0191 0.0123 0.0141
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0055
Schistosoma mansoni cytochrome P450 0.0127 0.0078 0.0089
Echinococcus multilocularis 0.0127 0.0078 0.0502
Echinococcus granulosus lysine specific demethylase 5A 0.009 0.0051 0.0329
Plasmodium vivax sugar transporter, putative 0.0031 0.0009 0.0145
Trypanosoma cruzi phytoene synthase, putative 0.0388 0.0263 0.3012
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.004 0.0016 0.0014
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0001 0.0001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.003 0.0009 0.0273
Toxoplasma gondii cytochrome p450 superfamily protein 0.0127 0.0078 0.1289
Echinococcus multilocularis epidermal growth factor receptor 0.0144 0.009 0.0578
Echinococcus multilocularis muscleblind protein 1 0.0276 0.0184 0.1185
Mycobacterium ulcerans Type I modular polyketide synthase 0.0056 0.0027 0.0026
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0001 0.0006
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0846 0.0589 0.3798
Toxoplasma gondii facilitative glucose transporter GT1 0.022 0.0144 0.2385
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0051 0.0024 0.0151
Onchocerca volvulus 0.0031 0.0009 0.0057
Loa Loa (eye worm) subtilase 0.0136 0.0084 0.0541
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0083 0.0047 0.03
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0117 0.007 0.007
Loa Loa (eye worm) ACC-1 protein 0.0846 0.0589 0.3791
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0019 0.0001 0.0003
Echinococcus granulosus glycine receptor subunit beta 0.0846 0.0589 0.3798
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.1214 0.0851 0.5481
Brugia malayi 6-phosphofructokinase 0.0131 0.0081 0.0519
Onchocerca volvulus 0.0031 0.0009 0.0057
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0078 0.0043 0.2118
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0016 0.0173
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0056 0.0027 0.0026
Echinococcus granulosus metabotropic glutamate receptor 2 0.0021 0.0002 0.0014
Brugia malayi follicle stimulating hormone receptor 0.1474 0.1036 0.6673
Brugia malayi major facilitator superfamily protein 0.0031 0.0009 0.006
Toxoplasma gondii hypothetical protein 0.0373 0.0253 0.4199
Mycobacterium leprae Conserved hypothetical protein 0.0127 0.0078 0.0077
Schistosoma mansoni DNA polymerase eta 0.003 0.0009 0.001
Brugia malayi Kelch motif family protein 0.0031 0.0009 0.0059
Schistosoma mansoni neurotransmitter gated ion channel 0.0385 0.0261 0.0299
Trypanosoma cruzi PAB1-binding protein , putative 0.0037 0.0014 0.0148
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0127 0.0078 0.0887
Echinococcus multilocularis dual specificity testis specific protein kinase 0.004 0.0016 0.0101
Onchocerca volvulus 0.0846 0.0589 0.3796
Brugia malayi G-protein coupled receptor 0.1214 0.0851 0.5481
Echinococcus granulosus SAM and MBT domain containing protein 0.0066 0.0034 0.022
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0059 0.0029 0.0033
Trypanosoma cruzi N-myristoyl transferase, putative 0.0043 0.0018 0.0201
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0081 0.3989
Loa Loa (eye worm) hypothetical protein 0.0066 0.0035 0.0222
Mycobacterium ulcerans Type I modular polyketide synthase 0.0056 0.0027 0.0026
Echinococcus granulosus nAChR subunit 0.0846 0.0589 0.3798
Mycobacterium ulcerans hydrolase 0.0026 0.0006 0.0004
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Schistosoma mansoni aminopeptidase A (M01 family) 0.0144 0.009 0.0103
Loa Loa (eye worm) zinc carboxypeptidase 0.0076 0.0041 0.0264
Schistosoma mansoni integrin alpha-ps 0.0044 0.0019 0.0022
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0281 0.0187 0.9296
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0076 0.0042 0.0267
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0157 0.0099 0.0098
Schistosoma mansoni tyrosine kinase 0.0388 0.0264 0.0302
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Leishmania major glucose transporter, lmgt3 0.0068 0.0036 0.0404
Loa Loa (eye worm) hypothetical protein 0.2201 0.1553 1
Schistosoma mansoni nAChR subunit 0.0846 0.0589 0.0674
Plasmodium vivax acyl-CoA synthetase, putative 0.003 0.0009 0.0133
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0127 0.0078 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1214 0.0851 0.549
Onchocerca volvulus 0.1214 0.0851 0.5489
Schistosoma mansoni jumonji domain containing protein 0.0023 0.0003 0.0004
Trypanosoma brucei histone deacetylase 4 0.0071 0.0038 0.0426
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0004 0.0043
Giardia lamblia CDC72 0.0043 0.0018 0.0808
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0846 0.0589 0.3798
Schistosoma mansoni hypothetical protein 0.0056 0.0027 0.0031
Echinococcus granulosus jumonji domain containing 1A 0.0023 0.0003 0.0022
Schistosoma mansoni tyrosine kinase 0.0076 0.0041 0.0047
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.0016 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0004 0.0043
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0013 0.0482
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.2107 0.1486 0.9585
Toxoplasma gondii leucyl aminopeptidase LAP 0.0541 0.0373 0.6197
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Schistosoma mansoni cpg binding protein 0.0048 0.0021 0.0024
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.2107 0.1486 0.9585
Plasmodium vivax JmjC domain containing protein 0.0023 0.0003 0.0048
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0004 0.0062
Schistosoma mansoni glucose transport protein 0.022 0.0144 0.0165
Onchocerca volvulus 0.0023 0.0003 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0165 0.8178
Loa Loa (eye worm) matrixin family protein 0.0047 0.0021 0.0132
Schistosoma mansoni hypothetical protein 0.0388 0.0263 0.0301
Schistosoma mansoni neuropeptide receptor 0.1214 0.0851 0.0974
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0009 0.0417
Onchocerca volvulus 0.0373 0.0253 0.1627
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0081 0.3989
Echinococcus granulosus o acyltransferase membrane bound domain 0.0019 0.0001 0.0003
Echinococcus granulosus histone deacetylase 1 0.0078 0.0043 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Echinococcus multilocularis 0.0076 0.0041 0.0265
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Loa Loa (eye worm) hypothetical protein 0.2107 0.1486 0.9569
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Schistosoma mansoni glutamate receptor AMPA 0.016 0.0101 0.0116
Mycobacterium ulcerans polyketide synthase 0.006 0.003 0.0029
Echinococcus multilocularis glutamate receptor 2 0.016 0.0101 0.0652
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1214 0.0851 0.5481
Trypanosoma brucei glycerol uptake protein, putative 0.0019 0.0001 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.003 0.0009 0.0096
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0009 0.0059
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0055 0.0026 0.0025
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0 0.0001
Mycobacterium leprae putative cytochrome p450 0.0127 0.0078 0.0077
Echinococcus granulosus flap endonuclease 1 0.0031 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0055
Schistosoma mansoni integrin beta subunit 0.012 0.0072 0.0083
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.006 0.003 0.0029
Brugia malayi hypothetical protein 0.0385 0.0261 0.168
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0019 0.0001 0.0003
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0181 0.0116 0.0748
Echinococcus granulosus tyrosine protein kinase ABL1 0.0394 0.0268 0.1725
Loa Loa (eye worm) hypothetical protein 0.005 0.0023 0.0148
Loa Loa (eye worm) prolyl oligopeptidase 0.0049 0.0022 0.0143
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Loa Loa (eye worm) jmjC domain-containing protein 0.009 0.0051 0.0329
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.004 0.0016 0.0014
Brugia malayi Serotonin receptor 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0144 0.009 0.0579
Trypanosoma cruzi histone deacetylase 1, putative 0.0078 0.0043 0.0488
Brugia malayi Zinc carboxypeptidase family protein 0.0076 0.0041 0.0265
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.01 0.0058 0.0663
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.0003 0.0033
Leishmania major alpha glucosidase II subunit, putative 0.0024 0.0004 0.0043
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Echinococcus multilocularis solute carrier family 22 0.0031 0.0009 0.0059
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.001 0.0151
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Loa Loa (eye worm) hypothetical protein 0.0541 0.0372 0.2395
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0541 0.0373 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0016 0.0175
Echinococcus granulosus thyrotropin releasing hormone receptor 0.1214 0.0851 0.549
Loa Loa (eye worm) acetylcholine receptor protein 0.0385 0.0261 0.1681
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0144 0.009 0.1491
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0066 0.0034 0.0039
Onchocerca volvulus 0.0441 0.0301 0.1939
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1214 0.0851 0.549
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0006 0.0005
Schistosoma mansoni cathepsin D (A01 family) 0.0145 0.0091 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0019 0.0021
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0019 0.0001 0.0003
Brugia malayi hypothetical protein 0.0031 0.0009 0.006
Loa Loa (eye worm) runx1 0.0023 0.0004 0.0024
Schistosoma mansoni glutaminase 0.0301 0.0201 0.0231
Onchocerca volvulus 0.0441 0.0301 0.1939
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0385 0.0261 0.1681
Echinococcus granulosus sodium:hydrogen exchanger 7 0.005 0.0023 0.0148
Loa Loa (eye worm) hypothetical protein 0.0404 0.0275 0.1769
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Echinococcus granulosus histone deacetylase 3 0.0078 0.0043 0.0278
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0056 0.0027 0.0026
Schistosoma mansoni histone deacetylase hda2 0.0073 0.0039 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0035 0.0225
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0038 0.0429
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0085 0.0048 0.0538
Onchocerca volvulus 0.011 0.0066 0.042
Leishmania major glucose transporter, lmgt1 0.0068 0.0036 0.0404
Echinococcus multilocularis cytosolic carboxypeptidase protein 5 0.0076 0.0041 0.0265
Brugia malayi Protein kinase domain containing protein 0.0047 0.0021 0.0133
Onchocerca volvulus 0.1214 0.0851 0.5489
Schistosoma mansoni subfamily M14A unassigned peptidase (M14 family) 0.0441 0.0301 0.0345
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0127 0.0078 0.0077
Brugia malayi neuropeptide F receptor 0.1214 0.0851 0.5481
Brugia malayi MBOAT family protein 0.0019 0.0001 0.0003
Giardia lamblia Histone deacetylase 0.0078 0.0043 0.2276
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1214 0.0851 0.0974
Echinococcus granulosus rhodopsin orphan GPCR 0.1214 0.0851 0.549
Brugia malayi polk-prov protein 0.0027 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0041 0.0261
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0024 0.0004 0.012
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0004 0.0185
Plasmodium vivax glycylpeptide N-tetradecanoyltransferase, putative 0.0043 0.0018 0.0291
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0081 0.3989
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0049 0.0022 0.014
Trypanosoma brucei trypanothione reductase 0.0069 0.0036 0.0413
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0008 0.0051
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Plasmodium vivax aspartyl proteinase, putative 0.0057 0.0028 0.0456
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0846 0.0589 0.3792
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.003 0.0009 0.001
Brugia malayi jmjC domain containing protein 0.009 0.0051 0.0329
Wolbachia endosymbiont of Brugia malayi Kef-type K+ transport system, membrane component 0.005 0.0023 0.0587
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0023 0.0003 0.0048
Echinococcus granulosus histone deacetylase 8 0.0034 0.0011 0.0072
Chlamydia trachomatis glutamine binding protein 0.0028 0.0007 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0 0.0003
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Trypanosoma cruzi histone deacetylase, putative 0.0071 0.0038 0.0424
Schistosoma mansoni hypothetical protein 0.0122 0.0074 0.0085
Loa Loa (eye worm) MBOAT family protein 0.0019 0.0001 0.0003
Brugia malayi Pre-SET motif family protein 0.0227 0.0149 0.0956
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0108 0.0064 0.0413
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0175 0.0112 0.0111
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0076 0.0041 0.202
Onchocerca volvulus 0.0023 0.0004 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1214 0.0851 0.0974
Entamoeba histolytica acyl-coA synthetase, putative 0.004 0.0016 0.0482
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0009 0.0008
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0127 0.0078 0.0077
Schistosoma mansoni glutamate receptor kainate 0.016 0.0101 0.0116
Onchocerca volvulus 0.0043 0.0018 0.0114
Schistosoma mansoni ferritin 0.002 0.0001 0.0001
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0846 0.0589 0.3791
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0023 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0184 0.0118 0.0762
Brugia malayi Thioredoxin reductase 0.0069 0.0036 0.0234
Echinococcus multilocularis g protein coupled receptor 0.1214 0.0851 0.549
Brugia malayi Dopamine receptor protein 2 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0012 0.0013
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0024 0.0004 0.0187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0 0.0003
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0127 0.0078 0.0077
Onchocerca volvulus 0.0144 0.009 0.0578
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0051 0.0326
Onchocerca volvulus Carboxypeptidase D homolog 0.0076 0.0041 0.0262
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0213 0.0139 0.0897
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0127 0.0078 0.0077
Toxoplasma gondii type I fatty acid synthase, putative 0.0062 0.0031 0.0509
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0006 0.0067
Echinococcus multilocularis flap endonuclease 1 0.0031 0.001 0.0062
Echinococcus granulosus neuropeptide Y receptor 0.1214 0.0851 0.549
Brugia malayi Dopamine receptor 0.1214 0.0851 0.5481
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0281 0.0187 0.214
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.000005704 0.0000065289
Schistosoma mansoni peptidase 0.0076 0.0041 0.0047
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.0043 0.2118
Entamoeba histolytica hypothetical protein 0.0043 0.0018 0.056
Trypanosoma brucei hypothetical protein, conserved 0.01 0.0058 0.0665
Echinococcus multilocularis nAChR subunit 0.0846 0.0589 0.3798
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0021 0.0002 0.0003
Schistosoma mansoni zinc finger protein 0.0019 0.0001 0.0001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0003 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0144 0.009 0.1026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1214 0.0851 0.549
Echinococcus multilocularis neuropeptides capa receptor 0.1214 0.0851 0.549
Echinococcus granulosus muscleblind protein 0.0276 0.0184 0.1185
Brugia malayi AMP-binding enzyme family protein 0.004 0.0016 0.0101
Echinococcus granulosus expressed conserved protein 0.0051 0.0023 0.015
Brugia malayi hypothetical protein 0.1214 0.0851 0.5481
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0009 0.0434
Brugia malayi hypothetical protein 0.005 0.0023 0.0148
Echinococcus multilocularis General substrate transporter 0.0189 0.0122 0.0785
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Entamoeba histolytica hypothetical protein 0.0043 0.0018 0.056
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0083 0.0047 0.03
Brugia malayi jmjC domain containing protein 0.0023 0.0003 0.0022
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.0081 0.0517
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0014
Echinococcus multilocularis microtubule associated protein 2 0.0777 0.054 0.3482
Schistosoma mansoni tyrosine kinase 0.0078 0.0043 0.0049
Echinococcus multilocularis solute carrier family 22 0.0031 0.0009 0.0059
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0075 0.0041 0.0262
Loa Loa (eye worm) hypothetical protein 0.0373 0.0253 0.1626
Onchocerca volvulus 0.0258 0.0171 0.1099
Echinococcus multilocularis rhodopsin orphan GPCR 0.1214 0.0851 0.549
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0281 0.0187 0.1207
Plasmodium vivax plasmepsin V, putative 0.0023 0.0003 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0 0.0003
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0019 0.0001 0.0001
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0846 0.0589 0.3792
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0059
Schistosoma mansoni protease m14 carboxypeptidase 0.0076 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0846 0.0589 0.3791
Loa Loa (eye worm) hypothetical protein 0.0385 0.0261 0.1681
Brugia malayi ImpB/MucB/SamB family protein 0.003 0.0009 0.0055
Brugia malayi Glutamate receptor 1 precursor 0.016 0.0101 0.0651
Echinococcus granulosus dual specificity testis-specific protein kinase 0.004 0.0016 0.0101
Schistosoma mansoni histone deacetylase 1 2 3 0.0034 0.0011 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.004 0.0016 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0025 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Loa Loa (eye worm) hypothetical protein 0.0264 0.0175 0.1126
Echinococcus multilocularis expressed protein 0.0339 0.0228 0.1472
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0 0.0003
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) TK/ABL protein kinase 0.0394 0.0268 0.1722
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0127 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.0062
Plasmodium falciparum plasmepsin I 0.0057 0.0028 0.0456
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.1214 0.0851 0.549
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0373 0.0253 0.0289
Echinococcus granulosus lysine specific demethylase 6a 0.0023 0.0003 0.0022
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0127 0.0078 0.0887
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0069 0.0036 0.0035
Echinococcus granulosus histone deacetylase 0.0071 0.0038 0.0242
Loa Loa (eye worm) hypothetical protein 0.0461 0.0315 0.2028
Plasmodium vivax SET domain protein, putative 0.0034 0.0012 0.0186
Loa Loa (eye worm) hypothetical protein 0.0388 0.0263 0.1695
Loa Loa (eye worm) hypothetical protein 0.0076 0.0041 0.0264
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0127 0.0078 0.0077
Trypanosoma cruzi aminopeptidase, putative 0.0281 0.0187 0.214
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0 0.0003
Toxoplasma gondii aldehyde dehydrogenase 0.0117 0.007 0.1165
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.006 0.003 0.0029
Echinococcus multilocularis mitochondrial sodium:hydrogen exchanger 9B2 0.005 0.0023 0.0148
Brugia malayi Cation transporter family protein 0.0846 0.0589 0.3792
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.1214 0.0851 0.549
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.3038 0.2149 0.246
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0013 0.038
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0075 0.0041 0.0262
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0 0.0001
Trypanosoma cruzi squalene synthase, putative 0.1244 0.0873 1
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0388 0.0263 0.0262
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0846 0.0589 0.3792
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0004 0.0045
Toxoplasma gondii flagellar/basal body protein 0.0076 0.0041 0.0676
Leishmania major cytochrome p450-like protein 0.0147 0.0092 0.1044
Echinococcus multilocularis cpg binding protein 0.0048 0.0021 0.0137
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0127 0.0078 0.0077
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.0043 0.2118
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0076 0.0041 0.0465
Echinococcus multilocularis glycine receptor subunit beta 0.0846 0.0589 0.3798
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0021 0.0002 0.0014
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0127 0.0078 0.0077
Onchocerca volvulus 0.0373 0.0253 0.1627
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0206 0.0134 0.6653
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0031 0.0354
Plasmodium falciparum thioredoxin reductase 0.0069 0.0036 0.0596
Onchocerca volvulus Fatty acid synthase homolog 0.0102 0.006 0.0382
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0013 0.0199
Plasmodium falciparum plasmepsin V 0.0023 0.0003 0.0045
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0127 0.0078 0.0077
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0281 0.0187 0.1207
Echinococcus multilocularis lysine specific demethylase 5A 0.0085 0.0048 0.0308
Plasmodium falciparum plasmepsin VIII, putative 0.0023 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481
Mycobacterium ulcerans Type I modular polyketide synthase 0.0056 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0101
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.1214 0.0851 0.0974
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0373 0.0253 0.0289
Echinococcus granulosus histone deacetylase 6 0.0073 0.0039 0.0251
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0003 0.0022
Echinococcus granulosus GPCR family 2 0.0056 0.0027 0.0176
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0144 0.009 0.1491
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0168
Loa Loa (eye worm) hypothetical protein 0.005 0.0023 0.0148
Schistosoma mansoni glutamate receptor NMDA 0.0341 0.023 0.0263
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0104 0.5138
Loa Loa (eye worm) hypothetical protein 0.1214 0.0851 0.5481

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.56 ug ml-1 Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetry ChEMBL. 850237
Potency (binding) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from structural similarity (ECO:0000027) Leishmania major 23720  
Annotator: aaronjr@u.washington.edu Comment: Drug: 26305-03-3. chemical inhibition with known cysteine peptidase inhibitors leads to reduced enzyme activity in vitro; References: 17028008
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania major 23720  
Annotator: aaronjr@u.washington.edu Comment: Drug: 26305-03-3. chemical inhibition with known cysteine peptidase inhibitors leads to reduced enzyme activity in vitro; References: 17028008
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania donovani 26075  
Annotator: crowther@u.washington.edu Comment: Drug: 160470-73-5 (Apstatin); Drug: 96551-81-4 (Arphamenine A); Drug: DL-Thiorphan. chemical inhibitors reduce LAP activity References: 12006595
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania major 26075  
Annotator: crowther@u.washington.edu Comment: Drug: 160470-73-5 (Apstatin); Drug: 96551-81-4 (Arphamenine A); Drug: DL-Thiorphan. chemical inhibitors reduce LAP activity References: 12006595
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania amazonensis 26075  
Annotator: crowther@u.washington.edu Comment: Drug: 160470-73-5 (Apstatin); Drug: 96551-81-4 (Arphamenine A); Drug: DL-Thiorphan. chemical inhibitors reduce LAP activity References: 12006595
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) multi-cellular organism (CARO:0000012) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Plasmodium chabaudi 333  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 12166515 9879894
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) multi-cellular organism (CARO:0000012) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Plasmodium falciparum 333  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 12166515 9879894
response to drug (GO:0042493) decreased sensitivity toward (PATO:0001550) bloodstream stage (PLO:0040) inferred from over expression (ECO:0000120) Plasmodium falciparum 2770  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 16286469
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) multi-cellular organism (CARO:0000012) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Plasmodium chabaudi 2770  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 16286469 9694371
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) multi-cellular organism (CARO:0000012) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Plasmodium falciparum 2770  
Annotator: saralph@unimelb.edu.au Comment: 012/Mar/09 References: 16286469 9694371

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

15 literature references were collected for this gene.

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