Detailed information for compound 64655

Basic information

Technical information
  • TDR Targets ID: 64655
  • Name: (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4- hydroxyphenyl)propanoyl]amino]propanoyl]amino ]-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S)- 1-(carboxymethylamino)-3-methyl-1-oxobutan-2- yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-o xopentanoic acid
  • MW: 783.868 | Formula: C38H53N7O11
  • H donors: 10 H acceptors: 11 LogP: -0.68 Rotable bonds: 28
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC(=O)CC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)O)C(C)C)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)O)N)C)Cc1ccccc1
  • InChi: 1S/C38H53N7O11/c1-20(2)31(37(55)40-19-30(49)50)45-38(56)32(21(3)4)44-35(53)27(15-16-29(47)48)42-36(54)28(18-23-9-7-6-8-10-23)43-33(51)22(5)41-34(52)26(39)17-24-11-13-25(46)14-12-24/h6-14,20-22,26-28,31-32,46H,15-19,39H2,1-5H3,(H,40,55)(H,41,52)(H,42,54)(H,43,51)(H,44,53)(H,45,56)(H,47,48)(H,49,50)/t22-,26-,27-,28-,31-,32-/m0/s1
  • InChiKey: FWGXLJYMZWCJJV-LJXGPVSSSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-5-[[(1S)-1-[[(1S)-1-(carboxymethylcarbamoyl)-2-methyl-propyl]carbamoyl]-2-methyl-propyl]amino]-5-oxo-pentanoic acid
  • (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-1-oxopropyl]amino]-1-oxo-3-phenylpropyl]amino]-5-[[(1S)-1-[[[(1S)-1-[(carboxymethylamino)-oxomethyl]-2-methylpropyl]amino]-oxomethyl]-2-methylpropyl]amino]-5-oxopentanoic acid
  • (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-3-methyl-1-oxo-butan-2-yl]amino]-3-methyl-1-oxo-butan-2-yl]amino]-5-oxo-pentanoic acid
  • (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-5-[[(1S)-1-[[(1S)-1-(carboxymethylcarbamoyl)-2-methyl-propyl]carbamoyl]-2-methyl-propyl]amino]-5-keto-valeric acid
  • (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-3-methyl-1-oxo-butan-2-yl]amino]-3-methyl-1-oxo-butan-2-yl]amino]-5-oxo-pentanoic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Delta opioid receptor Starlite/ChEMBL References
Mus musculus opioid receptor, delta 1 Starlite/ChEMBL References
Rattus norvegicus Mu opioid receptor Starlite/ChEMBL References
Cavia porcellus Mu opioid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi larval opioid receptor Mu opioid receptor   98 aa 100 aa 24.0 %
Onchocerca volvulus Mu opioid receptor   98 aa 96 aa 24.0 %
Echinococcus granulosus tachykinin peptides receptor 99D Mu opioid receptor   98 aa 93 aa 25.8 %
Schistosoma mansoni hypothetical protein Mu opioid receptor   98 aa 100 aa 23.0 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Mu opioid receptor   98 aa 89 aa 40.4 %
Brugia malayi Melatonin receptor type 1A Mu opioid receptor   98 aa 80 aa 22.5 %
Schistosoma mansoni thyrotropin-releasing hormone receptor Mu opioid receptor   98 aa 100 aa 27.0 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Mu opioid receptor   398 aa 397 aa 22.7 %
Schistosoma japonicum ko:K04165 Oamb gene product from transcript, putative Mu opioid receptor   98 aa 79 aa 34.2 %
Onchocerca volvulus Programmed cell death protein 5 homolog Mu opioid receptor   398 aa 323 aa 24.1 %
Schistosoma mansoni neuropeptide F-like receptor Mu opioid receptor   398 aa 335 aa 20.6 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 92 aa 23.9 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 79 aa 29.1 %
Schistosoma mansoni amine GPCR Mu opioid receptor   98 aa 86 aa 32.6 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 92 aa 31.5 %
Onchocerca volvulus Mu opioid receptor   98 aa 100 aa 25.0 %
Onchocerca volvulus Mu opioid receptor   98 aa 80 aa 22.5 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Mu opioid receptor   98 aa 80 aa 31.2 %
Onchocerca volvulus Mu opioid receptor   98 aa 85 aa 24.7 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Mu opioid receptor   98 aa 89 aa 38.2 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Mu opioid receptor   98 aa 93 aa 33.3 %
Onchocerca volvulus Mu opioid receptor   98 aa 79 aa 27.8 %
Schistosoma japonicum Neuropeptide Y receptor, putative Mu opioid receptor   98 aa 100 aa 29.0 %
Echinococcus multilocularis g protein coupled receptor Mu opioid receptor   98 aa 81 aa 24.7 %
Echinococcus multilocularis serotonin receptor Mu opioid receptor   98 aa 97 aa 35.1 %
Onchocerca volvulus Mu opioid receptor   98 aa 96 aa 28.1 %
Echinococcus multilocularis neuropeptide Y receptor Mu opioid receptor   98 aa 95 aa 32.6 %
Schistosoma japonicum 5-hydroxytryptamine receptor 4, putative Mu opioid receptor   98 aa 79 aa 36.7 %
Schistosoma mansoni biogenic amine receptor Mu opioid receptor   98 aa 91 aa 38.5 %
Echinococcus granulosus neuropeptide FF receptor 2 Mu opioid receptor   98 aa 84 aa 31.0 %
Brugia malayi GnHR receptor homolog Delta opioid receptor   372 aa 313 aa 18.5 %
Schistosoma mansoni neuropeptide receptor Mu opioid receptor   98 aa 93 aa 24.7 %
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor Mu opioid receptor   98 aa 100 aa 29.0 %
Schistosoma japonicum ko:K04282 thyrotropin-releasing hormone receptor, putative Mu opioid receptor   98 aa 100 aa 28.0 %
Onchocerca volvulus Mu opioid receptor   98 aa 87 aa 32.2 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Mu opioid receptor   98 aa 93 aa 25.8 %
Echinococcus granulosus neuropeptide receptor Mu opioid receptor   98 aa 88 aa 22.7 %
Onchocerca volvulus Mu opioid receptor   98 aa 93 aa 36.6 %
Schistosoma japonicum Neuropeptide Y receptor type 2, putative Mu opioid receptor   98 aa 79 aa 31.6 %
Loa Loa (eye worm) TYRA-2 protein Mu opioid receptor   98 aa 87 aa 31.0 %
Onchocerca volvulus RB1-inducible coiled-coil protein 1 homolog Mu opioid receptor   98 aa 96 aa 31.2 %
Loa Loa (eye worm) neuropeptide F receptor Delta opioid receptor   372 aa 317 aa 23.3 %
Onchocerca volvulus Phospholipase d-related homolog Mu opioid receptor   98 aa 82 aa 25.6 %
Echinococcus multilocularis neuropeptide FF receptor 2 Mu opioid receptor   98 aa 84 aa 31.0 %
Onchocerca volvulus Mu opioid receptor   98 aa 80 aa 35.0 %
Schistosoma mansoni adenoreceptor Mu opioid receptor   98 aa 88 aa 38.6 %
Schistosoma mansoni biogenic amine (dopamine) receptor Mu opioid receptor   98 aa 97 aa 35.1 %
Brugia malayi ORL1-like opioid receptor Delta opioid receptor   372 aa 300 aa 24.7 %
Schistosoma mansoni biogenic amine (5HT) receptor Mu opioid receptor   98 aa 97 aa 34.0 %
Echinococcus granulosus g protein coupled receptor Mu opioid receptor   98 aa 81 aa 24.7 %
Echinococcus multilocularis neuropeptide receptor Mu opioid receptor   98 aa 88 aa 22.7 %
Schistosoma japonicum Octopamine receptor, putative Mu opioid receptor   98 aa 98 aa 37.8 %
Schistosoma mansoni biogenic amine (5HT) receptor Mu opioid receptor   98 aa 97 aa 36.1 %
Onchocerca volvulus Glycoprotein hormone beta 5 homolog Mu opioid receptor   98 aa 92 aa 32.6 %
Echinococcus multilocularis biogenic amine (5HT) receptor Mu opioid receptor   98 aa 96 aa 30.2 %
Onchocerca volvulus Delta opioid receptor   372 aa 353 aa 21.0 %
Schistosoma mansoni growth hormone secretagogue receptor Mu opioid receptor   98 aa 93 aa 24.7 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 98 aa 31.6 %
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Mu opioid receptor   98 aa 97 aa 37.1 %
Echinococcus granulosus g protein coupled receptor Mu opioid receptor   98 aa 92 aa 26.1 %
Echinococcus granulosus biogenic amine 5HT receptor Mu opioid receptor   98 aa 97 aa 35.1 %
Schistosoma mansoni biogenic amine receptor Mu opioid receptor   98 aa 97 aa 38.1 %
Echinococcus multilocularis rhodopsin orphan GPCR Mu opioid receptor   98 aa 80 aa 23.8 %
Schistosoma japonicum Octopamine receptor, putative Mu opioid receptor   98 aa 88 aa 37.5 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Mu opioid receptor   398 aa 334 aa 23.1 %
Schistosoma japonicum Probable G-protein coupled receptor No9, putative Mu opioid receptor   98 aa 95 aa 28.4 %
Onchocerca volvulus Mu opioid receptor   98 aa 101 aa 20.8 %
Echinococcus granulosus neuropeptide Y receptor Mu opioid receptor   98 aa 95 aa 32.6 %
Onchocerca volvulus Delta opioid receptor   372 aa 349 aa 22.1 %
Schistosoma mansoni opsin-like receptor Mu opioid receptor   98 aa 80 aa 25.0 %
Echinococcus granulosus biogenic amine 5HT receptor Mu opioid receptor   98 aa 96 aa 30.2 %
Onchocerca volvulus Mu opioid receptor   98 aa 79 aa 21.5 %
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a Mu opioid receptor   98 aa 96 aa 29.2 %
Onchocerca volvulus Delta opioid receptor   372 aa 316 aa 26.9 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Delta opioid receptor   372 aa 315 aa 28.6 %
Echinococcus granulosus alpha 1A adrenergic receptor Mu opioid receptor   98 aa 92 aa 21.7 %
Echinococcus granulosus allatostatin A receptor Delta opioid receptor   372 aa 302 aa 27.8 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Delta opioid receptor   372 aa 330 aa 24.2 %
Schistosoma mansoni biogenic amine (dopamine) receptor Mu opioid receptor   98 aa 88 aa 39.8 %
Echinococcus granulosus thyrotropin releasing hormone receptor Delta opioid receptor   372 aa 330 aa 24.5 %
Echinococcus multilocularis allatostatin A receptor Delta opioid receptor   372 aa 302 aa 28.5 %
Schistosoma japonicum Muscarinic acetylcholine receptor M1, putative Mu opioid receptor   98 aa 95 aa 30.5 %
Brugia malayi G protein-coupled receptor Mu opioid receptor   98 aa 90 aa 31.1 %
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor Mu opioid receptor   98 aa 100 aa 29.0 %
Schistosoma mansoni peptide (allatostatin)-like receptor Delta opioid receptor   372 aa 353 aa 29.2 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 81 aa 35.8 %
Schistosoma japonicum Alpha-1A adrenergic receptor, putative Mu opioid receptor   98 aa 98 aa 34.7 %
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) Mu opioid receptor   98 aa 97 aa 36.1 %
Schistosoma mansoni rhodopsin-like orphan GPCR Mu opioid receptor   98 aa 85 aa 25.9 %
Onchocerca volvulus Delta opioid receptor   372 aa 386 aa 22.8 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 93 aa 30.1 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Delta opioid receptor   372 aa 320 aa 25.6 %
Schistosoma japonicum FMRFamide receptor, putative Mu opioid receptor   98 aa 109 aa 28.4 %
Onchocerca volvulus Mu opioid receptor   98 aa 79 aa 31.6 %
Schistosoma mansoni neuropeptide receptor Mu opioid receptor   98 aa 81 aa 34.6 %
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor Mu opioid receptor   98 aa 96 aa 32.3 %
Schistosoma japonicum Neuropeptide Y receptor, putative Mu opioid receptor   98 aa 88 aa 23.9 %
Onchocerca volvulus 26S proteasome non-ATPase regulatory subunit 1 homolog Mu opioid receptor   98 aa 80 aa 28.8 %
Schistosoma mansoni histamine-responsive GPCR (AAF21638) Mu opioid receptor   98 aa 99 aa 36.4 %
Echinococcus multilocularis tachykinin peptides receptor 99D Mu opioid receptor   98 aa 93 aa 25.8 %
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a Mu opioid receptor   98 aa 96 aa 29.2 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Mu opioid receptor   98 aa 90 aa 28.9 %
Schistosoma mansoni biogenic amine receptor Mu opioid receptor   98 aa 98 aa 35.7 %
Onchocerca volvulus Mu opioid receptor   98 aa 86 aa 33.7 %
Echinococcus multilocularis g protein coupled receptor Mu opioid receptor   98 aa 92 aa 26.1 %
Onchocerca volvulus Mu opioid receptor   98 aa 81 aa 33.3 %
Brugia malayi Serotonin/octopamine receptor family protein 7 Mu opioid receptor   98 aa 85 aa 32.9 %
Onchocerca volvulus Delta opioid receptor   372 aa 344 aa 22.1 %
Schistosoma mansoni neuropeptide F-like receptor Mu opioid receptor   98 aa 85 aa 32.9 %
Schistosoma japonicum Rhodopsin, putative Mu opioid receptor   398 aa 328 aa 23.2 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 96 aa 31.2 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Delta opioid receptor   372 aa 366 aa 22.7 %
Schistosoma mansoni neuropeptide receptor Mu opioid receptor   98 aa 95 aa 32.6 %
Onchocerca volvulus Mu opioid receptor   98 aa 81 aa 25.9 %
Loa Loa (eye worm) melatonin receptor type 1A Mu opioid receptor   98 aa 80 aa 22.5 %
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor Mu opioid receptor   98 aa 80 aa 37.5 %
Loa Loa (eye worm) hypothetical protein Mu opioid receptor   98 aa 85 aa 37.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0034 0.0081
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi PXA domain containing protein 0.0237 0.0682 0.1563
Trichomonas vaginalis hypothetical protein 0.0022 0.0036 0.0257
Onchocerca volvulus 0.006 0.015 0.1082
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0014 0.0088
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0143 0.0402 0.4556
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Loa Loa (eye worm) UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 0.004 0.0091 0.0207
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0142 0.158
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0015 0.0367
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0034 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0143 0.0402 0.092
Brugia malayi nuclear receptor NHR-88 0.001 0 0.0000046864
Echinococcus granulosus sterol regulatory element binding protein 0.009 0.0241 0.0569
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni o-linked n-acetylglucosamine transferase ogt 0.004 0.0091 0.0209
Echinococcus granulosus biogenic amine 5HT receptor 0.0165 0.0467 0.1104
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis pleckstrin y domain containing family A 0.0022 0.0036 0.0036
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0165 0.0467 0.1069
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0 0.0001
Leishmania major cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Giardia lamblia hypothetical protein 0.0143 0.0402 0.1143
Echinococcus granulosus Pleckstrin y 0.0022 0.0036 0.0084
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0142 0.158
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0125
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Echinococcus multilocularis dna polymerase eta 0.0021 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) thioredoxin reductase 0.0094 0.0253 0.0579
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0084 0.1106
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.021 0.0601 0.1378
Toxoplasma gondii Alpha-galactosidase 0.0016 0.0018 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0034 0.0078
Entamoeba histolytica G protein alpha subunit, putative 0.001 0 0.0004
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1178 0.3514 0.3514
Brugia malayi Oxysterol binding protein 0.0022 0.0036 0.0081
Schistosoma mansoni nuclear receptor 0.001 0 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0067 0.0732
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus multilocularis calcium activated potassium channel 0.0011 0.0004 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Echinococcus granulosus transient receptor potential cation channel 0.0168 0.0476 0.1126
Loa Loa (eye worm) hypothetical protein 0.0143 0.0402 0.092
Entamoeba histolytica cell surface protease gp63, putative 0.0012 0.0006 0.007
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0022 0.0036 0.0084
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0022 0.0036 0.0255
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus Ribosomal protein L34a 0.0136 0.0379 0.0896
Onchocerca volvulus 0.005 0.012 0.0866
Schistosoma mansoni plexin 0.0065 0.0166 0.038
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0165 0.0467 0.0467
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0034 0.0081
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0142 0.158
Brugia malayi hypothetical protein 0.0016 0.0019 0.0044
Onchocerca volvulus 0.0053 0.0131 0.0946
Onchocerca volvulus 0.0022 0.0036 0.0255
Loa Loa (eye worm) hypothetical protein 0.005 0.012 0.0274
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.146 0.4362 1
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0122 0.2479
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0034 0.0245
Onchocerca volvulus Protein patched homolog 0.0013 0.0008 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis fmrfamide receptor 0.0165 0.0467 0.0467
Schistosoma mansoni axis inhibition protein axin 0.0237 0.0682 0.1564
Plasmodium vivax importin-beta 2, putative 0.0032 0.0067 0.168
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0122 0.1355
Echinococcus granulosus importin subunit beta 1 0.0032 0.0067 0.016
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0045 0.0103
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0049 0.0356
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0034 0.0077
Echinococcus granulosus serotonin receptor 0.0165 0.0467 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Schistosoma mansoni netrin receptor unc5 0.0032 0.0066 0.0151
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.029 0.0665
Onchocerca volvulus 0.0165 0.0467 0.3379
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0259 0.0259
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0036 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0122 0.1671
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0083 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0112 0.0308 0.0308
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Schistosoma mansoni hypothetical protein 0.0029 0.0058 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Loa Loa (eye worm) galactosyltransferase 0.0184 0.0524 0.1202
Brugia malayi Patched related family protein 4 0.0013 0.0008 0.0019
Schistosoma mansoni oxysterol-binding protein 1 0.0022 0.0036 0.0081
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0143 0.0402 0.092
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Toxoplasma gondii thioredoxin reductase 0.0094 0.0253 0.0716
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0015 0.0042
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0161
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0015 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Brugia malayi Metabotropic glutamate receptor precursor. 0.0232 0.0667 0.1528
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0143 0.0402 0.0402
Schistosoma mansoni jumonji domain containing protein 0.0076 0.02 0.0458
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Brugia malayi tailless protein 0.001 0 0.0000046864
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0034 0.0081
Loa Loa (eye worm) PDE1B protein 0.0143 0.0402 0.092
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0142 0.158
Echinococcus granulosus metabotropic glutamate receptor 2 0.0194 0.0554 0.131
Brugia malayi MAP kinase sur-1 0.0057 0.0142 0.0324
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0686 0.0686
Entamoeba histolytica PH domain containing protein 0.0022 0.0036 0.0415
Echinococcus granulosus tumor protein p63 0.034 0.0993 0.2349
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0143 0.0402 0.095
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0237 0.0682 0.1614
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.0257 0.0257
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.003 0.003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0233 0.0672 0.1539
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0143 0.0402 0.4556
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0122 0.2479
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0042 0.0096
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0006 0.0013
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0221 0.0506
Brugia malayi Guanylyl cyclase protein 23 0.0025 0.0045 0.0103
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Onchocerca volvulus 0.0013 0.0008 0.0059
Trichomonas vaginalis kinesin light chain, putative 0.0022 0.0036 0.026
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0022 0.0036 0.0884
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0 0.0001
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.001 0 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0233 0.0672 0.0672
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0143 0.0402 1
Treponema pallidum NADH oxidase 0.0033 0.0068 0.0604
Loa Loa (eye worm) beta-1,4-galactosyltransferase VII 0.0048 0.0116 0.0265
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.001
Echinococcus multilocularis Regulator of G protein signaling 20 0.0237 0.0682 0.0682
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0034 0.0078
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Echinococcus multilocularis neuropeptide receptor 0.0165 0.0467 0.0467
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Brugia malayi G-protein coupled receptor 0.0165 0.0467 0.1069
Echinococcus multilocularis neuropeptide s receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0399 0.4532
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0046 0.0492
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0022 0.0036 0.0366
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0122 0.1598
Loa Loa (eye worm) glycosyl transferase 0.002 0.003 0.0068
Toxoplasma gondii hypothetical protein 0.0022 0.0036 0.0101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0165 0.0467 0.0467
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0078 0.1462
Echinococcus granulosus beta 14 galactosyltransferase 7 0.0048 0.0116 0.0274
Onchocerca volvulus 0.0015 0.0015 0.0104
Brugia malayi MAX-1A 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Schistosoma mansoni hypothetical protein 0.0345 0.1008 0.2312
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.001 0 0.0001
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0237 0.0682 0.1564
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0068
Mycobacterium tuberculosis Probable oxidoreductase 0.0238 0.0687 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Onchocerca volvulus 0.0165 0.0467 0.3379
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Entamoeba histolytica hypothetical protein 0.0237 0.0682 0.7979
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0028 0.0054 0.0392
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0122 0.1598
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0034 0.0348
Brugia malayi intermediate filament protein 0.0053 0.0131 0.0299
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0015 0.0107
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0042 0.0438
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Loa Loa (eye worm) cytochrome P450 0.0015 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Echinococcus multilocularis GRB2 associated binding protein 3 0.0022 0.0036 0.0036
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0143 0.0402 0.095
Loa Loa (eye worm) Plekhf2 protein 0.0022 0.0036 0.0081
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0084 0.2081
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0004 0.0042
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0233 0.0672 0.154
Loa Loa (eye worm) hypothetical protein 0.0053 0.0131 0.0299
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni hypothetical protein 0.0038 0.0084 0.0193
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0066 0.1196
Onchocerca volvulus 0.0165 0.0467 0.3379
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0022 0.0036 0.0255
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Giardia lamblia DINP protein human, muc B family 0.0021 0.0034 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0034 0.0077
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0221 0.0506
Brugia malayi jmjC domain containing protein 0.0037 0.0082 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Onchocerca volvulus 0.0013 0.0008 0.0059
Echinococcus granulosus neuropeptide Y receptor 0.0165 0.0467 0.1104
Schistosoma mansoni dynamin 0.0022 0.0036 0.0081
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0015 0.0042
Onchocerca volvulus 0.0021 0.0034 0.0245
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis Metazoa galactosyltransferase 0.0156 0.0439 0.0439
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0068 0.0155
Onchocerca volvulus 0.0032 0.0065 0.0469
Onchocerca volvulus 0.0022 0.0036 0.0255
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0094 0.0253 0.3601
Echinococcus granulosus expressed protein 0.001 0 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0046 0.1158
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0221 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0014 0.0121
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0137 0.0137
Echinococcus multilocularis beta 1 syntrophin 0.0022 0.0036 0.0036
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0098 0.1078
Brugia malayi hypothetical protein 0.002 0.003 0.0068
Echinococcus granulosus oxysterol binding protein 3 0.0022 0.0036 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0083 0.0913
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0078 0.9166
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Echinococcus multilocularis thioredoxin glutathione reductase 0.0094 0.0253 0.0253
Brugia malayi hypothetical protein 0.0237 0.0682 0.1563
Echinococcus granulosus metabotropic glutamate receptor 5 0.0285 0.0828 0.1958
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.1008 0.2311
Schistosoma mansoni loxhd1 0.002 0.003 0.0068
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0028 0.0054 0.0578
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0015 0.0172
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0066 0.0151
Leishmania major extracellular receptor, putative 0.0022 0.0036 0.0368
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0221 0.0506
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0165 0.0467 0.107
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0004 0.0009
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.001 0 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0014 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0014 0.0088
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0165 0.0467 0.1069
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0402 0.2911
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0059 0.0149 0.034
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0068 0.0739
Schistosoma mansoni biogenic amine (5HT) receptor 0.0165 0.0467 0.107
Echinococcus multilocularis neuropeptide Y receptor 0.0165 0.0467 0.0467
Echinococcus granulosus lamin 0.0053 0.0131 0.031
Schistosoma mansoni protein kinase 0.0025 0.0045 0.0104
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.001 0 0.0002
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0083 0.019
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Brugia malayi Patched protein homolog 1 0.0013 0.0008 0.0019
Plasmodium falciparum thioredoxin reductase 0.0033 0.0068 0.1697
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0122 0.2479
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0004 0.0004
Trichomonas vaginalis set domain proteins, putative 0.0469 0.138 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1178 0.3514 0.8314
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0034 0.0034
Echinococcus multilocularis neuropeptides capa receptor 0.0165 0.0467 0.0467
Brugia malayi Dopamine receptor protein 2 0.0165 0.0467 0.1069
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Entamoeba histolytica hypothetical protein 0.0237 0.0682 0.7979
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0014 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0068 0.1697
Brugia malayi Presenilin spe-4 0.0085 0.0224 0.0514
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0014 0.0088
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.001 0 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Brugia malayi G protein-coupled receptor 0.0165 0.0467 0.1069
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0238 0.0687 1
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Brugia malayi hypothetical protein 0.001 0 0.0000046864
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0233 0.0672 0.0672
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0034 0.0034
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0196 0.1419
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0237 0.0682 0.1563
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0036 0.0081
Trypanosoma brucei unspecified product 0.0021 0.0034 0.0348
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Echinococcus multilocularis oxysterol binding protein 3 0.0022 0.0036 0.0036
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis neuropeptides capa receptor 0.0165 0.0467 0.0467
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0083 0.2075
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0019 0.0045
Toxoplasma gondii O-linked N-acetylglucosamine transferase 0.004 0.009 0.0255
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.009 0.0241 0.0551
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.029 0.029
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0015 0.0006
Brugia malayi Cytohesin 3 0.0022 0.0036 0.0081
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.092
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi Dopamine receptor 0.0165 0.0467 0.1069
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0083 0.0237
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Brugia malayi conserved hypotetical protein 0.001 0 0.0000046864
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.146 0.4362 1
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0015 0.0006
Schistosoma mansoni inositol monophosphatase 0.0036 0.0078 0.0178
Brugia malayi Dopamine receptor protein 1 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0078 0.0911
Echinococcus multilocularis lamin 0.0053 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus granulosus G protein coupled receptor kinase 1 0.0883 0.2625 0.621
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0042 0.0438
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.0054 0.0124
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0022 0.0036 0.0415
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Brugia malayi hypothetical protein 0.0113 0.031 0.0709
Echinococcus multilocularis protein patched 0.009 0.0241 0.0241
Brugia malayi Sema domain containing protein 0.0027 0.0052 0.0118
Brugia malayi jmjC domain containing protein 0.0096 0.0259 0.0594
Echinococcus multilocularis regulator of G protein signaling 3 0.0237 0.0682 0.0682
Onchocerca volvulus 0.002 0.003 0.0214
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0 0.0001
Schistosoma mansoni syntrophin 0.0022 0.0036 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0034 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Brugia malayi Cytochrome P450 family protein 0.0032 0.0066 0.0151
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus Niemann Pick C1 protein 0.0209 0.06 0.142
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0057 0.141
Plasmodium vivax phosphodiesterase gamma, putative 0.0143 0.0402 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.1104
Mycobacterium ulcerans hypothetical protein 0.0016 0.0018 0.007
Toxoplasma gondii exonuclease III APE 0.0038 0.0083 0.0236
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0165 0.0467 0.107
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0082 0.0195
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.0402 0.895
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0214 0.0615 0.8939
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0082 0.0189
Echinococcus multilocularis pdz domain containing protein 0.0022 0.0036 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0014 0.0088
Brugia malayi PHD-finger family protein 0.0011 0.0004 0.0009
Leishmania major protein kinase, putative 0.0028 0.0054 0.0578
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0033 0.0074
Schistosoma mansoni myotubularin-related protein 0.0022 0.0036 0.0081
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.0921
Brugia malayi protein C24B5.3 0.0013 0.0008 0.0019
Trypanosoma brucei unspecified product 0.0015 0.0014 0.0121
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0007 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Echinococcus granulosus dnaJ subfamily B 0.0449 0.1321 0.3125
Schistosoma mansoni polycystin 1-related 0.002 0.003 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0034 0.0077
Schistosoma mansoni cellular tumor antigen P53 0.005 0.012 0.0275
Schistosoma mansoni ran 0.0024 0.0042 0.0096
Treponema pallidum hypothetical protein 0.0016 0.0018 0.0000051679
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0083 0.019
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0399 0.4532
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0034 0.0077
Schistosoma mansoni opsin-like receptor 0.0165 0.0467 0.107
Echinococcus granulosus g protein coupled receptor 0.0165 0.0467 0.1104
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0143 0.0402 0.4556
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Schistosoma mansoni zinc finger protein 0.0022 0.0036 0.0081
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0125
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0034 0.0077
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0046 0.0492
Echinococcus multilocularis axis inhibition protein axin 0.0237 0.0682 0.0682
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Giardia lamblia O-linked GlcNAc transferase 0.0023 0.004 0.0114
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0233 0.0672 0.1589
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.031 0.0733
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0068 0.0739
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Brugia malayi Latrophilin receptor protein 2 0.0096 0.0257 0.059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1223 0.365 0.8368
Brugia malayi AKH receptor 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Echinococcus granulosus guanine nucleotide binding protein subunit 0.001 0 0.0001
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni growth hormone secretagogue receptor 0.0165 0.0467 0.107
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0014 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0122 0.1355
Echinococcus granulosus GPCR family 2 0.0096 0.0257 0.0609
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0083 0.0913
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0034 0.0077
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0034 0.0078
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.029 0.328
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0034 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0014 0.0088
Onchocerca volvulus 0.0165 0.0467 0.3379
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0034 0.0348
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0883 0.2625 0.2625
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.029 0.3393
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis g protein coupled receptor 0.0165 0.0467 0.0467
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus neuropeptide s receptor 0.0165 0.0467 0.1104
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0241 0.0696 0.7929
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Onchocerca volvulus 0.0022 0.0036 0.0255
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.0083 0.0221 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.001 0 0.0001
Leishmania major protein kinase, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0022 0.0036 0.0081
Brugia malayi Cytochrome P450 family protein 0.0036 0.0078 0.0177
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0122 0.2479
Echinococcus multilocularis exocyst complex component 2 0.0012 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0233 0.0672 0.1589
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.0095
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0022 0.0036 0.0081
Echinococcus multilocularis nmda type glutamate receptor 0.0022 0.0036 0.0036
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0156
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0022 0.0036 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Onchocerca volvulus 0.0049 0.0116 0.0839
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0013 0.0008 0.0059
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0022 0.0036 0.0257
Schistosoma mansoni hypothetical protein 0.0083 0.0221 0.0506
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1035 0.3083 0.3083
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0067 0.0154
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0034 0.0374
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0033 0.0033
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0034 0.0245
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.4556
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0067 0.0191
Echinococcus multilocularis G protein coupled receptor 139 0.0165 0.0467 0.0467
Echinococcus granulosus dna polymerase kappa 0.0021 0.0034 0.008
Toxoplasma gondii hypothetical protein 0.0022 0.0036 0.0101
Brugia malayi cytochrome P450 0.0015 0.0014 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Trichomonas vaginalis centaurin alpha, putative 0.0022 0.0036 0.0257
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0083 0.0604
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0004 0.001
Schistosoma mansoni lamin 0.0053 0.0131 0.03
Echinococcus granulosus microtubule associated protein 2 0.0694 0.2059 0.4872
Schistosoma mansoni GTP-binding protein alpha subunit 0.001 0 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0178 0.0408
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0098 0.1078
Giardia lamblia PHD finger protein 15 0.0029 0.0058 0.0166
Entamoeba histolytica ARF GTPase activating protein, putative 0.0022 0.0036 0.0415
Brugia malayi hypothetical protein 0.0238 0.0686 0.1572
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.029 0.0665
Loa Loa (eye worm) hypothetical protein 0.005 0.0121 0.0278
Echinococcus multilocularis ankyrin repeat protein 0.0163 0.0461 0.0461
Echinococcus granulosus beta 1 syntrophin 0.0022 0.0036 0.0084
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0042 0.0118
Schistosoma mansoni lipoxygenase 0.0056 0.0137 0.0315
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.029 0.3254
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0122 0.2479
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0302 0.0878 0.2012
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0156 0.0443
Toxoplasma gondii melibiase subfamily protein 0.0112 0.0308 0.0874
Trichomonas vaginalis alpha chimerin, putative 0.0022 0.0036 0.0257
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0022 0.0036 0.0257
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0022 0.0036 0.0084
Brugia malayi Sema domain containing protein 0.0027 0.0052 0.0118
Loa Loa (eye worm) inositol-1 0.0036 0.0078 0.0178
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0143 0.0402 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0 0.0000046864
Loa Loa (eye worm) hypothetical protein 0.011 0.0301 0.069
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Schistosoma mansoni myosin xvIII 0.0165 0.0467 0.107
Schistosoma mansoni survival motor neuron protein 0.0049 0.0116 0.0266
Echinococcus granulosus neuropeptides capa receptor 0.0165 0.0467 0.1104
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.001 0 0.0001
Brugia malayi CXXC zinc finger family protein 0.0032 0.0065 0.0148
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0022 0.0036 0.0884
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0165 0.0467 0.1104
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Echinococcus granulosus regulator of G protein signaling 7 0.0237 0.0682 0.1614
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0142 0.0335
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.1178 0.3514 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.1035 0.3083 0.7067
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0068 0.0878
Entamoeba histolytica tyrosin kinase, putative 0.0015 0.0016 0.0182
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0034 0.0034
Onchocerca volvulus 0.0165 0.0467 0.3379
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Schistosoma mansoni biogenic amine receptor 0.0165 0.0467 0.107
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0015 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.1321 0.1321
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica hypothetical protein, conserved 0.0022 0.0036 0.0415
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.001 0 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0143 0.0402 0.4556
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0142 0.0324
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0233 0.0672 0.154
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0022 0.0036 0.0036
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0143 0.0402 0.095
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.0402 0.5806
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0014
Echinococcus granulosus cytohesin 1 0.0022 0.0036 0.0084
Brugia malayi Uncoordinated protein 104 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Schistosoma mansoni zinc finger protein 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0143 0.0402 0.092
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0209 0.06 0.1376
Brugia malayi PHD-finger family protein 0.0029 0.0058 0.0133
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0022 0.0036 0.0257
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.0036 0.0081
Schistosoma mansoni cpg binding protein 0.0033 0.007 0.0161
Echinococcus multilocularis oxysterol binding protein 1 0.0022 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Brugia malayi orphan nuclear receptor NR2E1 0.001 0 0.0000046864
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0241 0.0696 0.7929
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.015 0.0343
Trypanosoma cruzi NIMA-related kinase, putative 0.0028 0.0054 0.0578
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1178 0.3514 0.8314
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0137 0.0325
Echinococcus granulosus regulator of G protein signaling 7 0.0237 0.0682 0.1614
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0034 0.0077
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0066 0.0151
Echinococcus granulosus tyrosine kinase 0.0025 0.0045 0.0107
Brugia malayi Pre-SET motif family protein 0.006 0.015 0.0342
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Echinococcus granulosus DCC interacting protein 13 beta 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0068 0.0739
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0054 0.0578
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0034 0.0081
Plasmodium falciparum glutathione reductase 0.0094 0.0253 0.6296
Echinococcus granulosus plexin a4 0.0077 0.0202 0.0477
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0143 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Leishmania major hypothetical protein, conserved 0.0022 0.0036 0.0366
Trypanosoma cruzi NIMA-related kinase, putative 0.0028 0.0054 0.0578
Brugia malayi hypothetical protein 0.0027 0.0052 0.0118
Schistosoma mansoni intermediate filament proteins 0.0053 0.0131 0.03
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0082 0.0188
Echinococcus granulosus oxysterol binding protein 9 0.0022 0.0036 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0065 0.0166 0.038
Plasmodium falciparum lipid/sterol:H+ symporter 0.0013 0.0008 0.0209
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0084 0.1594
Brugia malayi neuropeptide F receptor 0.0165 0.0467 0.1069
Echinococcus multilocularis G-protein coupled receptor, putative 0.0165 0.0467 0.0467
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0241 0.0696 0.5046
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Echinococcus granulosus transcription factor collier 0.0012 0.0006 0.0014
Schistosoma mansoni zinc finger protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0165 0.0467 0.0467
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0221 0.0523
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0028 0.0054 0.0578
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0034 0.0077
Trichomonas vaginalis centaurin gamma, putative 0.0022 0.0036 0.0257
Plasmodium vivax thioredoxin reductase, putative 0.0094 0.0253 0.6296
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Schistosoma mansoni nuclear hormone receptor 0.001 0 0.0001
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Echinococcus multilocularis actin binding protein anillin 0.0022 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0165 0.0467 0.1104
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0013 0.0008 0.0059
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0165 0.0467 0.0467
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Schistosoma mansoni trimeric G-protein alpha o subunit 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0068 0.0739
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0022 0.0036 0.0036
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Brugia malayi PXA domain containing protein 0.0237 0.0682 0.1563
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0165 0.0467 0.0467
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0034 0.0448
Schistosoma mansoni biogenic amine receptor 0.0165 0.0467 0.107
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0034 0.0077
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Toxoplasma gondii N-acetylgalactosaminyl transferase 0.002 0.003 0.0085
Brugia malayi hypothetical protein 0.001 0 0.0000046864
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0015 0.0034
Echinococcus multilocularis cytohesin 1 0.0022 0.0036 0.0036
Schistosoma mansoni inositol monophosphatase 0.0036 0.0078 0.0178
Plasmodium falciparum PH domain-containing protein, putative 0.0022 0.0036 0.0884
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0067 0.0855
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0022 0.0036 0.0084
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0022 0.0036 0.0036
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni hypothetical protein 0.0032 0.0066 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0122 0.2479
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Onchocerca volvulus Protein patched homolog 0.0013 0.0008 0.0059
Echinococcus granulosus snurportin 1 0.0345 0.1008 0.2386
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Brugia malayi ORL1-like opioid receptor 0.0165 0.0467 0.1069
Echinococcus multilocularis g-protein coupled receptor 0.0165 0.0467 0.0467
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0125
Echinococcus multilocularis serotonin receptor 0.0165 0.0467 0.0467
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0165 0.0467 0.1069
Brugia malayi DNA-binding protein LAG-1 0.0012 0.0006 0.0013
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0014 0.0041
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0066 0.0719
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0068 0.0739
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0196 0.0449
Schistosoma mansoni adenoreceptor 0.0165 0.0467 0.107
Brugia malayi G protein-coupled receptor F59B2.13 0.0165 0.0467 0.1069
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0054 0.0578
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0057 0.141
Loa Loa (eye worm) hypothetical protein 0.0238 0.0686 0.1572
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0165 0.0467 0.1069
Echinococcus granulosus peregrin 0.0029 0.0058 0.0138
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0068 0.0193
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis centaurin beta, putative 0.0022 0.0036 0.0257
Loa Loa (eye worm) hypothetical protein 0.0302 0.0878 0.2012
Echinococcus multilocularis Ribosomal protein L34a 0.0136 0.0379 0.0379
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0096 0.0257 0.0257
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0077 0.0077
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.0921
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0066 0.0719
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0058 0.1455
Schistosoma mansoni neuropeptide f receptor 76f 0.0165 0.0467 0.107
Leishmania major GTP-binding protein, putative 0.0024 0.0042 0.0438
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0058 0.0138
Plasmodium falciparum phosphodiesterase gamma, putative 0.0143 0.0402 1
Brugia malayi Death domain containing protein 0.0032 0.0066 0.015
Echinococcus granulosus orexin receptor type 2 0.0165 0.0467 0.1104
Echinococcus multilocularis beta 1,4 galactosyltransferase 7 0.0048 0.0116 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.2059 0.472
Schistosoma mansoni hypothetical protein 0.0206 0.0591 0.1354
Loa Loa (eye worm) hypothetical protein 0.005 0.0122 0.0279
Toxoplasma gondii AtPH1 family protein 0.0022 0.0036 0.0101
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0059 0.0149 0.034
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Loa Loa (eye worm) neuropeptide F receptor 0.0165 0.0467 0.1069
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0068 0.7691
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0 0.0001
Brugia malayi Regulator of G protein signaling domain containing protein 0.0237 0.0682 0.1563
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Schistosoma mansoni hypothetical protein 0.0027 0.0052 0.0119
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0739
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0067 0.0067
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0067 0.0732
Loa Loa (eye worm) hypothetical protein 0.0206 0.0591 0.1354
Echinococcus granulosus sex peptide receptor 0.0165 0.0467 0.1104
Echinococcus multilocularis dro:myosuppressin receptor 0.0165 0.0467 0.0467
Brugia malayi G-protein coupled receptor 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor E75 0.001 0 0.0000046864
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0028 0.0054 0.0392
Echinococcus multilocularis plexin a4 0.0077 0.0202 0.0202
Echinococcus granulosus semaphorin 5B 0.0027 0.0052 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0034 0.0077
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Echinococcus multilocularis rac serine:threonine kinase 0.0028 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0034 0.0081
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Plasmodium falciparum importin beta, putative 0.0032 0.0067 0.168
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0068 0.0739
Entamoeba histolytica p21-activated kinase 0.0028 0.0054 0.0632
Brugia malayi Dynamin 0.0022 0.0036 0.0081
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0015 0.0006
Echinococcus multilocularis myotubularin protein 13 0.0022 0.0036 0.0036
Echinococcus multilocularis Pleckstrin y 0.0022 0.0036 0.0036
Brugia malayi Cadps2 protein 0.0022 0.0036 0.0081
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0015 0.0367
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0057 0.141
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0 0.0001
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0058 0.0058
Brugia malayi Pleckstrin Homology Domain 0.0022 0.0036 0.0081
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0125
Echinococcus granulosus oxysterol binding protein 1 0.0022 0.0036 0.0084
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Echinococcus multilocularis fmrfamide receptor 0.0165 0.0467 0.0467
Echinococcus multilocularis axis inhibition protein axin 0.0237 0.0682 0.0682
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0034 0.0246
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0022 0.0036 0.0084
Loa Loa (eye worm) oxidoreductase 0.0015 0.0015 0.0033
Echinococcus multilocularis O glycosyltransferase 0.004 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.005 0.0122 0.0279
Loa Loa (eye worm) hypothetical protein 0.0052 0.0128 0.0293
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0057 0.016
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0591 0.1354
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Trypanosoma brucei trypanothione reductase 0.0094 0.0253 0.2854
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0034 0.0077
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.0048 0.0116 0.0265
Echinococcus granulosus glutamate receptor 2 0.0022 0.0036 0.0084
Loa Loa (eye worm) UDP-Galactose:b-N-acetylglucosamine b1,4-galactosyltransferase 4 0.0048 0.0116 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0083 0.2075
Onchocerca volvulus 0.0053 0.0131 0.0946
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0241 0.0696 0.7929
Loa Loa (eye worm) hypothetical protein 0.0143 0.0402 0.092
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0034 0.0077
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0241 0.0696 0.5046
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0014 0.0121
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0022 0.0036 0.0884
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.0036 0.0081
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0241 0.0696 0.1596
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0877 1
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0034 0.0078
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0036 0.0884
Loa Loa (eye worm) rho-GTPase-activating 0.0022 0.0036 0.0081
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.012
Schistosoma mansoni plexin 0.0038 0.0084 0.0193
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0165 0.0467 0.0467
Schistosoma mansoni hypothetical protein 0.0015 0.0014 0.0033
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0 0.0000046864
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0066 0.015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0034 0.0078
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Trypanosoma brucei PH domain containing protein, putative 0.0022 0.0036 0.0366
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Plasmodium falciparum oxysterol-binding protein, putative 0.0022 0.0036 0.0884
Echinococcus granulosus tachykinin peptides receptor 99D 0.0165 0.0467 0.1104
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0165 0.0467 0.107
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Echinococcus granulosus neuropeptide Y receptor 0.0165 0.0467 0.1104
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.029 0.3393
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.015 0.0343
Entamoeba histolytica PH domain containing protein 0.0022 0.0036 0.0415
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0049 0.0356
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Schistosoma mansoni patched 1 0.009 0.0241 0.0552
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0 0.0000046864
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0036 0.0036
Echinococcus granulosus dna polymerase eta 0.0021 0.0034 0.008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0015 0.0004
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0237 0.0682 0.4944
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0028 0.0054 0.0578
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0014 0.0088
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.003 0.0744
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0025 0.0624
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.015 0.0343
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0015 0.0006
Echinococcus granulosus presenilin 0.0241 0.0696 0.1647
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0001 0.0002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.005
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.029 0.0664
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0057 0.0467
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0045
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Onchocerca volvulus 0.0165 0.0467 0.3379
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0102
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1223 0.365 0.8368
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0165 0.0467 0.0467
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0014 0.0088
Schistosoma mansoni hypothetical protein 0.0449 0.1321 0.3028
Echinococcus granulosus calcium dependent secretion activator 1 0.0022 0.0036 0.0084
Echinococcus granulosus 7tm_1 domain containing protein 0.0165 0.0467 0.1104
Echinococcus granulosus cpg binding protein 0.0033 0.007 0.0167
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0014
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Toxoplasma gondii Oxysterol-binding protein 0.0022 0.0036 0.0101
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Entamoeba histolytica presenilin 1 peptidase, putative 0.0241 0.0696 0.8144
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0109
Echinococcus granulosus nuclear factor of activated T cells 5 0.0311 0.0906 0.2145
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0004 0.0026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0238 0.0687 1
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.0855 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0214 0.0615 0.893
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0233 0.0672 0.154
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0034 0.0034
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.0119
Brugia malayi UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 0.004 0.0091 0.0207
Echinococcus multilocularis GPCR, family 3, C terminal 0.0038 0.0083 0.0083
Leishmania major hypothetical protein, conserved 0.0025 0.0046 0.0492
Echinococcus multilocularis transcription factor collier 0.0012 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Schistosoma mansoni vav2 0.0022 0.0036 0.0081
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0165 0.0467 0.1069
Schistosoma mansoni ap endonuclease 0.0038 0.0083 0.0191
Echinococcus granulosus glutamate receptor 2 0.0022 0.0036 0.0084
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.0855 1
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0066 0.0156
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.104
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0057 0.041
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0034 0.0374
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Echinococcus granulosus GRB2 associated binding protein 3 0.0022 0.0036 0.0084
Brugia malayi Syntrophin-1 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus Niemann Pick C1 protein 0.0299 0.0871 0.206
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni goodpasture antigen-binding protein 0.0022 0.0036 0.0081
Schistosoma mansoni alpha-1 adrenergic receptor 0.0165 0.0467 0.107
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.1119 0.3337 0.765
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0034 0.0077
Brugia malayi Serotonin receptor 0.0165 0.0467 0.1069
Brugia malayi Niemann-Pick C1 protein precursor 0.0209 0.06 0.1376
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.029 0.4098
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0034 0.0077
Leishmania major serine/threonine-protein kinase a, putative 0.0028 0.0054 0.0578
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0068 0.1697
Schistosoma mansoni hypothetical protein 0.0113 0.031 0.071
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0 0.0001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0142 0.158
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Schistosoma mansoni nuclear receptor 0.001 0 0.0001
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0034 0.0077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0078 0.085
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0022 0.0036 0.0036
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0066 0.0151
Onchocerca volvulus 0.0165 0.0467 0.3379
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi regulator of G-protein signaling rgs-7 0.0237 0.0682 0.1563
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0066 0.015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0068 0.1238
Brugia malayi RE15519p 0.0165 0.0467 0.1069
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0078 0.0177
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0165 0.0467 0.0467
Plasmodium falciparum LCCL domain-containing protein 0.002 0.003 0.0744
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0194 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0022 0.0036 0.0084
Echinococcus granulosus peptide allatostatin:somatostatin 0.0165 0.0467 0.1104
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Brugia malayi hypothetical protein 0.0025 0.0046 0.0106
Loa Loa (eye worm) phosphofructokinase 0.0106 0.029 0.0664
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Leishmania major cytochrome p450-like protein 0.0032 0.0066 0.0719
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0214 0.0615 0.8939
Echinococcus granulosus atrial natriuretic peptide receptor 0.0022 0.0036 0.0084
Brugia malayi Presenilin family protein 0.0241 0.0696 0.1595
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0142 0.0403
Echinococcus multilocularis tyrosine kinase 0.0025 0.0045 0.0045
Brugia malayi Nuclear hormone receptor E75 0.001 0 0.0000046864
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Cytochrome P450 family protein 0.0032 0.0066 0.0151
Echinococcus granulosus pdz domain containing protein 0.0022 0.0036 0.0084
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0015 0.0091
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0034 0.0081
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0034 0.0245
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0057 0.0662
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0148 0.0417 0.118
Schistosoma mansoni cytochrome P450 0.0015 0.0014 0.0033
Trichomonas vaginalis ran, putative 0.0024 0.0042 0.0303
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0 0.0000046864
Trichomonas vaginalis protein transport protein sec7, putative 0.0022 0.0036 0.0257
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0028 0.0054 0.0578
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0143 0.0402 0.092
Echinococcus granulosus biogenic amine 5HT receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) RecQ helicase 0.0021 0.0033 0.0074
Loa Loa (eye worm) doublecortin family protein 0.002 0.003 0.0068
Brugia malayi hypothetical protein 0.0027 0.0052 0.0118
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0143 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Echinococcus granulosus g-protein coupled receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis g protein coupled receptor 0.0165 0.0467 0.0467
Echinococcus multilocularis RUN 0.002 0.003 0.003
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0739
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Schistosoma mansoni oxysterol-binding protein 1 0.0022 0.0036 0.0081
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0142 0.0335
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0165 0.0467 0.107
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.001 0 0.0001
Echinococcus granulosus G protein coupled receptor 139 0.0165 0.0467 0.1104
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0022 0.0036 0.0036
Schistosoma mansoni biogenic amine (5HT) receptor 0.0165 0.0467 0.107
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Schistosoma mansoni hypothetical protein 0.0083 0.0221 0.0506
Brugia malayi Bromodomain containing protein 0.0029 0.0058 0.0133
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus pleckstrin y domain containing family A 0.0022 0.0036 0.0084
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Brugia malayi hypothetical protein 0.0085 0.0224 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Plasmodium falciparum phd finger protein, putative 0.0029 0.0058 0.1455
Echinococcus granulosus somatostatin receptor 0.0165 0.0467 0.1104
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0028 0.0054 0.0153
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Loa Loa (eye worm) hypothetical protein 0.0096 0.0257 0.059
Leishmania major importin beta-1 subunit, putative 0.0026 0.0049 0.0521
Schistosoma mansoni metabotropic glutamate receptor 0.0113 0.031 0.071
Schistosoma mansoni tyrosine kinase 0.0025 0.0045 0.0104
Trypanosoma cruzi extracellular receptor, putative 0.0022 0.0036 0.0368
Echinococcus granulosus lamin dm0 0.0053 0.0131 0.031
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0042 0.0099
Echinococcus granulosus Metazoa galactosyltransferase 0.0184 0.0524 0.1241
Schistosoma mansoni lipoxygenase 0.002 0.003 0.0068
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0022 0.0036 0.0257
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0068 0.1697
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0233 0.0672 0.1539
Echinococcus multilocularis Oxysterol binding protein 11 0.0022 0.0036 0.0036
Brugia malayi hypothetical protein 0.0011 0.0004 0.0008
Echinococcus multilocularis peregrin 0.0029 0.0058 0.0058
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0058 0.0134
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0122 0.1355
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0035 0.0078
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.0257 0.0609
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0068 0.0194
Echinococcus multilocularis snurportin 1 0.0345 0.1008 0.1008
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0238 0.0687 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.1035 0.3083 0.7067
Echinococcus granulosus RUN 0.002 0.003 0.0071
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Onchocerca volvulus Alhambra homolog 0.0029 0.0058 0.0421
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0141 0.0334
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0033 0.0237
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0015 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0034 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Trichomonas vaginalis centaurin/arf, putative 0.0022 0.0036 0.0257
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.029 0.415
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus Oxysterol binding protein 11 0.0022 0.0036 0.0084
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0034 0.0077
Schistosoma mansoni nuclear hormone receptor 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0014 0.0088
Echinococcus granulosus dynamin 1 0.0022 0.0036 0.0084
Schistosoma mansoni histamine h1 receptor 0.0165 0.0467 0.107
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0004 0.0009
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0125
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0034 0.0078
Schistosoma mansoni ap endonuclease 0.0038 0.0083 0.0191
Onchocerca volvulus Neuropeptide F receptor homolog 0.0165 0.0467 0.3379
Brugia malayi hypothetical protein 0.0085 0.0224 0.0514
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0014 0.0088
Schistosoma mansoni axis inhibition protein axin 0.0237 0.0682 0.1564
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.015 0.0354
Echinococcus granulosus bloom syndrome protein 0.0021 0.0033 0.0077
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0006 0.0014
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.003 0.003
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0015 0.0015 0.0104
Echinococcus granulosus Pleckstrin y 0.0022 0.0036 0.0084
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0036 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0034 0.0078
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0009
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0042 0.104
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0034 0.0077
Echinococcus granulosus neuropeptide receptor 0.0165 0.0467 0.1104
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.0402 0.5769
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis protein transport protein sec7, putative 0.0022 0.0036 0.0257
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0004 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Brugia malayi Patched related family protein 12 0.0013 0.0008 0.0019
Brugia malayi Melatonin receptor type 1A 0.0165 0.0467 0.1069
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Schistosoma mansoni hypothetical protein 0.0083 0.0221 0.0506
Mycobacterium tuberculosis Probable dehydrogenase 0.0214 0.0615 0.8939
Brugia malayi Protein kinase domain containing protein 0.0028 0.0054 0.0123
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Echinococcus granulosus hypothetical protein 0.0165 0.0467 0.1104
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0046 0.0492
Brugia malayi nuclear hormone receptor 0.0021 0.0034 0.0077
Loa Loa (eye worm) RNA binding protein 0.0062 0.0155 0.0355
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Echinococcus granulosus expressed conserved protein 0.0197 0.0562 0.133
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0083 0.0913
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0415
Loa Loa (eye worm) hypothetical protein 0.0237 0.0682 0.1563
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0143 0.0402 0.095
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Loa Loa (eye worm) plexin A 0.0077 0.0202 0.0462
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0165 0.0467 0.0467
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0402 0.2911
Toxoplasma gondii phosphatidylinositol transfer protein 0.0022 0.0036 0.0101
Brugia malayi CHE-14 protein 0.009 0.0241 0.0551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0034 0.0077
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0034 0.0077
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Onchocerca volvulus outspread protein homolog 0.0022 0.0036 0.0255
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.001 0 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0014 0.0121
Echinococcus multilocularis Ankyrin 0.0032 0.0067 0.0067
Brugia malayi beta-1,4-galactosyltransferase VII 0.0048 0.0116 0.0265
Brugia malayi RNA binding protein 0.0062 0.0155 0.0355
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.029 0.328
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0014 0.0088
Onchocerca volvulus Protein melted homolog 0.0022 0.0036 0.0255
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1183 0.3529 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Schistosoma mansoni opsin-like receptor 0.0165 0.0467 0.107
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0028 0.0054 0.0578
Brugia malayi larval opioid receptor 0.0165 0.0467 0.1069
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0015 0.0091
Echinococcus multilocularis beta adrenergic receptor kinase 0.1119 0.3337 0.3337
Echinococcus granulosus neuropeptide receptor A26 0.0165 0.0467 0.1104
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0418
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0042 0.0095
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0016 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0033
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0083 0.0604
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis Rho GTPase activating protein 24 0.0022 0.0036 0.0036
Onchocerca volvulus 0.0013 0.0008 0.0059
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi protein C24B5.3 0.0013 0.0008 0.0019
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.029 0.3393
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0028 0.0054 0.0578
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0028 0.0054 0.0578
Echinococcus multilocularis neuropeptide FF receptor 2 0.0165 0.0467 0.0467
Echinococcus granulosus guanine nucleotide binding protein G protein 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0112 0.0308 0.0308
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0 0.0001
Brugia malayi probable spectrin beta chain 0.0022 0.0036 0.0081
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0142 0.0142
Loa Loa (eye worm) sema domain-containing protein 0.0027 0.0052 0.0118
Onchocerca volvulus 0.0469 0.1381 1
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0143 0.0402 0.0402
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0022 0.0036 0.0084
Schistosoma mansoni hypothetical protein 0.0029 0.0056 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Brugia malayi Plexin repeat family protein 0.0065 0.0166 0.038
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Brugia malayi steroid hormone receptor 0.0021 0.0034 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0034 0.0077
Echinococcus granulosus thioredoxin glutathione reductase 0.0094 0.0253 0.0598
Brugia malayi Oxysterol-binding protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0152 0.0349
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Trypanosoma brucei rac serine-threonine kinase, putative 0.0028 0.0054 0.0578
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0165 0.0467 0.0467
Brugia malayi Melibiase family protein 0.0075 0.0196 0.0448
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Toxoplasma gondii glycosyl transferase 0.002 0.003 0.0085
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0057 0.0161
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0015 0.0015
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Schistosoma mansoni lamin 0.0053 0.0131 0.03
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0034 0.0081
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0237 0.0682 0.1564
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi Presenilin spe-4 0.0085 0.0224 0.0514
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0093 0.022
Leishmania major hypothetical protein, conserved 0.0143 0.0402 0.4556
Schistosoma mansoni neuropeptide F-like receptor 0.0165 0.0467 0.107
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0015 0.0091
Echinococcus multilocularis cpg binding protein 0.0033 0.007 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Schistosoma mansoni DNA polymerase eta 0.0021 0.0034 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0066 0.0151
Echinococcus multilocularis tumor protein p63 0.034 0.0993 0.0993
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0165 0.0467 0.107
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0142 0.0401
Loa Loa (eye worm) hypothetical protein 0.0075 0.0196 0.0448
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.029 0.328
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0034 0.0448
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0034 0.0034
Brugia malayi regulator of G-protein signaling egl-10 0.0237 0.0682 0.1563
Echinococcus multilocularis lamin dm0 0.0053 0.0131 0.0131
Brugia malayi Doublecortin family protein 0.002 0.003 0.0068
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0036 0.0084
Schistosoma mansoni beta-14-galactosyltransferase 0.0184 0.0524 0.1202
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0412 0.1209 0.2771
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0058 0.0166
Entamoeba histolytica Ran family GTPase 0.0024 0.0042 0.0489
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi neuropeptide F receptor 0.0165 0.0467 0.1069
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0068 0.0193
Echinococcus granulosus regulator of G protein signaling 3 0.0237 0.0682 0.1614
Brugia malayi AMP-binding enzyme family protein 0.005 0.0122 0.0279
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Leishmania major hypothetical protein, conserved 0.0143 0.0402 0.4556
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0057 0.041
Onchocerca volvulus 0.0165 0.0467 0.3379
Brugia malayi metabotropic glutamate receptor type 2 0.0113 0.031 0.0709
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.003 0.0071
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0083 0.1588
Brugia malayi glutathione reductase 0.0094 0.0253 0.0579
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0068 0.1238
Brugia malayi Importin beta-1 subunit 0.0032 0.0067 0.0154
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0133
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0022 0.0036 0.0366
Schistosoma mansoni hypothetical protein 0.0165 0.0467 0.107
Schistosoma mansoni centaurin alpha 0.0022 0.0036 0.0081
Onchocerca volvulus 0.0015 0.0015 0.0104
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0034 0.0078
Plasmodium falciparum thioredoxin reductase 0.0094 0.0253 0.6296
Brugia malayi GnHR receptor homolog 0.0165 0.0467 0.1069
Entamoeba histolytica hypothetical protein 0.0028 0.0054 0.0632
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0034 0.008
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0084 1
Brugia malayi TBC domain containing protein 0.0022 0.0036 0.0081
Brugia malayi nuclear receptor RXR 0.001 0 0.0000046864
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Loa Loa (eye worm) melatonin receptor type 1A 0.0165 0.0467 0.1069
Echinococcus multilocularis beta 1,4 N acetylgalactosaminyltransferase 0.0048 0.0116 0.0116
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0058 0.0133
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0083 0.1102
Leishmania major DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0034 0.0078
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0237 0.0682 0.0682
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0034 0.0078
Onchocerca volvulus 0.0015 0.0015 0.0104
Loa Loa (eye worm) latrophilin receptor protein 2 0.0096 0.0257 0.059
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0034 0.0077
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0143 0.0402 0.4556
Echinococcus multilocularis neuropeptide Y receptor 0.0165 0.0467 0.0467
Leishmania major trypanothione reductase 0.0094 0.0253 0.2854
Schistosoma mansoni ran 0.0024 0.0042 0.0096
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.003 0.0071
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0213 0.061 0.1399
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0034 0.0034
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Schistosoma mansoni neuropeptide receptor 0.0165 0.0467 0.107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Echinococcus granulosus neuropeptide receptor 0.0165 0.0467 0.1104
Schistosoma mansoni serine/threonine protein kinase 0.146 0.4362 1
Brugia malayi Patched related family protein 10 0.0013 0.0008 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.031 0.071
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0013 0.0008 0.0059
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0022 0.0036 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0014 0.0088
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0122 0.1426
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0057 0.5917
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0015 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Schistosoma mansoni n-acetylgalactosaminyltransferase 0.002 0.003 0.0068
Onchocerca volvulus 0.005 0.0122 0.0881
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0078 0.0221
Trichomonas vaginalis centaurin/arf, putative 0.0022 0.0036 0.0257
Echinococcus multilocularis GPCR, family 2 0.0096 0.0257 0.0257
Entamoeba histolytica hypothetical protein 0.0237 0.0682 0.7979
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0068 0.0494
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0122 0.1426
Schistosoma mansoni serine/threonine protein kinase 0.1119 0.3337 0.765
Brugia malayi RNA, U transporter 1 0.0092 0.0247 0.0565
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0015 0.0006
Brugia malayi Galactosyltransferase family protein 0.0048 0.0116 0.0265
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0078 0.0564
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0015 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi sulfakinin receptor protein 0.0165 0.0467 0.1069
Onchocerca volvulus 0.0165 0.0467 0.3379
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0 0.0001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0237 0.0682 0.1564
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0068 0.0739
Schistosoma mansoni amine GPCR 0.0165 0.0467 0.107
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.015 0.015
Brugia malayi nuclear hormone receptor 0.001 0 0.0000046864
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0209 0.06 0.7022
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Echinococcus granulosus beta-adrenergic receptor kinase 0.1119 0.3337 0.7895
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.1104
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0034 0.0348
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0082 0.0189
Schistosoma mansoni hypothetical protein 0.0049 0.0116 0.0266
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0028 0.0054 0.0578
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0165 0.0467 0.107
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0014 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0057 0.016
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0056 0.0128
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0142 0.158
Onchocerca volvulus Putative zinc finger protein 0.0022 0.0036 0.0255
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0033 0.0237
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0078 0.0564
Schistosoma mansoni semaphorin 5-related 0.0027 0.0052 0.0119
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) glutamate receptor 0.0091 0.0244 0.0559
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0022 0.0036 0.0257
Brugia malayi Presenilin spe-4 0.0085 0.0224 0.0514
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus granulosus polypeptide N acetylgalactosaminyltransferase 0.002 0.003 0.0071
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0048 0.0113
Echinococcus multilocularis DCC interacting protein 13 beta 0.0022 0.0036 0.0036
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.4556
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0083 0.0083
Schistosoma mansoni rab6-interacting 0.002 0.003 0.0068
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0165 0.0467 0.1069
Echinococcus granulosus tm gpcr rhodopsin 0.0165 0.0467 0.1104
Echinococcus multilocularis semaphorin 5B 0.0027 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0143 0.0402 0.092
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0155 0.0355
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0192
Giardia lamblia Hypothetical protein 0.0143 0.0402 0.1143
Loa Loa (eye worm) hypothetical protein 0.006 0.015 0.0342
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0221 0.0221
Echinococcus granulosus guanine nucleotide binding protein subunit 0.001 0 0.0001
Echinococcus multilocularis Niemann Pick C1 protein 0.0209 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni beta-14-galactosyltransferase 0.0184 0.0524 0.1202
Mycobacterium tuberculosis Probable reductase 0.0214 0.0615 0.8939
Brugia malayi hypothetical protein 0.002 0.003 0.0068
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0112 0.0308 0.073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0046 0.1158
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.0855 0.2433
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0012 0.0309
Loa Loa (eye worm) RGS-3 protein 0.0237 0.0682 0.1563
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0042 0.0096
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0046 0.0132
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.029 0.2102
Echinococcus granulosus g protein coupled receptor 0.0165 0.0467 0.1104
Loa Loa (eye worm) hypothetical protein 0.005 0.0122 0.0279
Echinococcus granulosus Regulator of G protein signaling 20 0.0237 0.0682 0.1614
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1223 0.365 0.8636
Brugia malayi Serotonin receptor 0.0165 0.0467 0.1069
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0014 0.0088
Echinococcus granulosus intermediate filament protein 0.0053 0.0131 0.031
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0014 0.0088
Echinococcus multilocularis 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis regulator of G protein signaling 3 0.0237 0.0682 0.0682
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0022 0.0036 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1223 0.365 0.8368
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0014 0.0088
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.029 0.0664
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0 0.0000046864
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0165 0.0467 0.1104
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Echinococcus multilocularis serotonin receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0036 0.0884
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0015 0.0042
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.001 0 0.0002
Echinococcus multilocularis musashi 0.0053 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0000046864
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0066 0.0156
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0068 0.0068
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Schistosoma mansoni neuropeptide F-like receptor 0.0165 0.0467 0.107
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) TYRA-2 protein 0.0165 0.0467 0.1069
Echinococcus multilocularis sterol regulatory element binding protein 0.009 0.0241 0.0241
Brugia malayi Receptor family ligand binding region containing protein 0.0025 0.0045 0.0103
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0068 0.1697
Giardia lamblia O-linked GlcNAc transferase 0.004 0.009 0.0256
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0302 0.0878 0.2012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Loa Loa (eye worm) G-protein coupled receptor 0.0165 0.0467 0.1069
Mycobacterium ulcerans hypothetical protein 0.0159 0.0448 1
Echinococcus multilocularis neuropeptide receptor 0.0165 0.0467 0.0467
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0221 0.0523
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0165 0.0467 0.107
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.002 0.003 0.0068
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0122 0.1426
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0068 0.7663
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0034 0.0034
Schistosoma mansoni serine/threonine-protein kinase 0.0028 0.0054 0.0124
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0093 0.0093
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0165 0.0467 0.1069
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0045 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Echinococcus multilocularis somatostatin receptor 0.0165 0.0467 0.0467
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0038 0.0083 0.019
Brugia malayi hypothetical protein 0.0085 0.0224 0.0514
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0034 0.0081
Echinococcus granulosus axis inhibition protein axin 0.0237 0.0682 0.1614
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0034 0.0078
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni hypothetical protein 0.002 0.003 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0078 0.0184
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Echinococcus granulosus GPCR family 3 C terminal 0.0038 0.0083 0.0197
Loa Loa (eye worm) patched family protein 0.0013 0.0008 0.0019
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0004 0.0004
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0083 0.0913
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.2059 0.2059
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0165 0.0467 0.0467
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0066 0.0475
Brugia malayi IPT/TIG domain containing protein 0.0012 0.0006 0.0013
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0068 0.0494
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0014 0.0125
Onchocerca volvulus 0.0165 0.0467 0.3379
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0027 0.0052 0.0119
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Echinococcus granulosus fmrfamide receptor 0.0165 0.0467 0.1104
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0016 0.0018 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.0877 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0098 0.1078
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0028 0.0054 0.1346
Echinococcus granulosus regulator of G protein signaling 3 0.0237 0.0682 0.1614
Brugia malayi Tachykinin-like peptides receptor 99D 0.0165 0.0467 0.1069
Echinococcus multilocularis Metazoa galactosyltransferase 0.0184 0.0524 0.0524
Schistosoma mansoni glutamate receptor NMDA 0.0022 0.0036 0.0082
Schistosoma mansoni hypothetical protein 0.0087 0.0231 0.0529
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0066 0.0719
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0106
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.015
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus multilocularis dynamin 1 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0154
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) hypothetical protein 0.009 0.0241 0.0551
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0116 0.0266
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0049 0.0356
Loa Loa (eye worm) presenilin spe-4 0.0085 0.0224 0.0514
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1415 0.4227 0.4227
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Schistosoma mansoni dynamin 0.0022 0.0036 0.0081
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0022 0.0036 0.0081
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0165 0.0467 0.0467
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0034 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.1119 0.3337 0.765
Echinococcus granulosus ankyrin repeat protein 0.0163 0.0461 0.1091
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0165 0.0467 0.107
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0022 0.0036 0.0036
Brugia malayi Pre-SET motif family protein 0.0412 0.1209 0.2771
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0259 0.0613
Echinococcus multilocularis expressed conserved protein 0.0197 0.0562 0.0562
Echinococcus granulosus axis inhibition protein axin 0.0237 0.0682 0.1614
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0034 0.0348
Echinococcus granulosus exocyst complex component 2 0.0012 0.0006 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0034 0.0081
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Entamoeba histolytica hypothetical protein 0.0028 0.0054 0.0632
Echinococcus granulosus O glycosyltransferase 0.004 0.0091 0.0216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Loa Loa (eye worm) glutathione reductase 0.0094 0.0253 0.0579
Brugia malayi putative neuropeptide receptor 0.0165 0.0467 0.1069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0103
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0142 0.0142
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0083 0.0975
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0241 0.0696 0.5046
Brugia malayi 6-phosphofructokinase 0.0106 0.029 0.0664
Onchocerca volvulus Poor gastrulation protein homolog 0.0038 0.0083 0.0601
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0128
Brugia malayi nuclear receptor RXR 0.0011 0.0004 0.0008
Onchocerca volvulus 0.0022 0.0036 0.0255
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0059 0.0149 0.034
Echinococcus granulosus allatostatin A receptor 0.0165 0.0467 0.1104
Onchocerca volvulus 0.0165 0.0467 0.3379
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0028 0.0054 0.0578
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0214 0.0615 0.8939
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0015 0.0091
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.0855 1
Schistosoma mansoni metabotropic glutamate receptor 0.0194 0.0554 0.1269
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Loa Loa (eye worm) nuclear hormone receptor 0.001 0 0.0000046864
Toxoplasma gondii hypothetical protein 0.0049 0.0116 0.033
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.029 0.6358
Echinococcus granulosus neuropeptide FF receptor 2 0.0165 0.0467 0.1104
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0068
Brugia malayi Thioredoxin reductase 0.0094 0.0253 0.0579
Echinococcus multilocularis presenilin 0.0241 0.0696 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0155 0.0355
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Loa Loa (eye worm) DR-78 0.001 0 0.0000046864
Onchocerca volvulus 0.0165 0.0467 0.3379
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Echinococcus multilocularis orexin receptor type 2 0.0165 0.0467 0.0467
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0015 0.0033
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0012 0.0034
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Schistosoma mansoni rab6-interacting 0.002 0.003 0.0068
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.015 0.0424
Schistosoma mansoni regulator of G protein signaling 0.0237 0.0682 0.1564
Brugia malayi AMP-binding enzyme family protein 0.005 0.0122 0.0279
Schistosoma mansoni cpg binding protein 0.0033 0.007 0.0161
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0077 0.1015
Echinococcus multilocularis hypothetical protein 0.0027 0.0052 0.0052
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0005 0.012
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0042 0.0438
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Schistosoma mansoni nuclear receptor nhr-48 0.001 0 0.0001
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0015 0.0107
Echinococcus granulosus neuropeptides capa receptor 0.0165 0.0467 0.1104
Brugia malayi Uncoordinated protein 44 0.0032 0.0066 0.015
Brugia malayi nuclear receptor NHR-88 0.0021 0.0034 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Brugia malayi Galactosyltransferase family protein 0.0184 0.0524 0.1202
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0402 0.4556
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0096 0.0257 0.059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.015 0.0343
Brugia malayi Inositol-1 0.0036 0.0078 0.0178
Echinococcus multilocularis regulator of G protein signaling 0.0237 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0068
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0056 0.0128
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0028 0.0054 0.0578
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0022 0.0036 0.0255
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0008
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0067 0.0774
Schistosoma mansoni importin beta-1 0.0032 0.0067 0.0155
Brugia malayi hypothetical protein 0.0022 0.0036 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Brugia malayi Calcitonin receptor-like protein seb-1 0.0302 0.0878 0.2012
Onchocerca volvulus 0.0022 0.0036 0.0255
Schistosoma mansoni cpg binding protein 0.0032 0.0065 0.0149
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Brugia malayi Myosin head containing protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) sema domain-containing protein 0.0027 0.0052 0.0118
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1035 0.3083 0.7293
Loa Loa (eye worm) G-protein coupled receptor 0.0165 0.0467 0.1069
Schistosoma mansoni biogenic amine receptor 0.0165 0.0467 0.107
Echinococcus multilocularis regulator of G protein signaling 7 0.0237 0.0682 0.0682
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0165 0.0467 0.3379
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0015 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.015 0.015
Echinococcus granulosus receptor type guanylyl cyclase 0.0025 0.0045 0.0107
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.029 0.0686
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0057 0.016
Echinococcus granulosus tm gpcr rhodopsin 0.1415 0.4227 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis protein dispatched 1 0.0103 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Plasmodium vivax SET domain protein, putative 0.006 0.015 0.3726
Plasmodium vivax patched family protein, putative 0.0013 0.0008 0.0209
Schistosoma mansoni tyrosine kinase 0.0025 0.0045 0.0104
Echinococcus granulosus guanine nucleotide binding protein G protein 0.001 0 0.0001
Brugia malayi ecdysone receptor 0.001 0 0.0000046864
Echinococcus multilocularis receptor type guanylyl cyclase 0.0025 0.0045 0.0045
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0022 0.0036 0.0415
Toxoplasma gondii patched family protein 0.0013 0.0008 0.0024
Onchocerca volvulus 0.0022 0.0036 0.0255
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0025 0.0045 0.0326
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0155 0.0155
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0034 0.0348
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Echinococcus granulosus g protein coupled receptor 0.0165 0.0467 0.1104
Echinococcus granulosus semaphorin 1A 0.0027 0.0052 0.0123
Loa Loa (eye worm) neuropeptide F receptor 0.0165 0.0467 0.1069
Echinococcus granulosus beta 14 N acetylgalactosaminyltransferase 0.0048 0.0116 0.0274
Brugia malayi PH domain containing protein 0.0022 0.0036 0.0081
Plasmodium falciparum calcium-dependent protein kinase 7 0.0028 0.0054 0.1346
Brugia malayi phosphofructokinase 0.0106 0.029 0.0664
Schistosoma mansoni rho gtpase activating protein 0.0022 0.0036 0.0081
Schistosoma mansoni hypothetical protein 0.0038 0.0083 0.0191
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0058 0.0166
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0083 0.0786
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Echinococcus multilocularis Pleckstrin y 0.0022 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0012 0.0006 0.007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0045 0.0103
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Echinococcus granulosus calcium activated potassium channel 0.0011 0.0004 0.0009
Schistosoma mansoni hypothetical protein 0.0096 0.0257 0.059
Trypanosoma cruzi trypanothione reductase, putative 0.0094 0.0253 0.2854
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0131 0.0299
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0066 0.0066
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0165 0.0467 0.1104
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0143 0.0402 0.4556
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) uncoordinated protein 104 0.0022 0.0036 0.0081
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0122 0.2479
Echinococcus granulosus rhodopsin orphan GPCR 0.0165 0.0467 0.1104
Brugia malayi Presenilin-like protein At2g29900 0.0085 0.0224 0.0514
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0036 0.0884
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0574
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0014 0.0088
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0022 0.0036 0.0036
Onchocerca volvulus 0.0025 0.0045 0.0326
Echinococcus granulosus Protein patched homolog 1 0.009 0.0241 0.0569
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0068 0.1238
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0078 0.0078
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0263 0.0762 0.1748
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0022 0.0036 0.0081
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0155 0.0355
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0046 0.1158
Onchocerca volvulus 0.0013 0.0008 0.0059
Echinococcus multilocularis Pleckstrin y 0.0022 0.0036 0.0036
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0034 0.0077
Brugia malayi follicle stimulating hormone receptor 0.0389 0.114 0.2612
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Plasmodium falciparum glutathione reductase 0.0033 0.0068 0.1697
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0028 0.0054 0.0578
Echinococcus granulosus expressed protein 0.0237 0.0682 0.1614
Echinococcus granulosus 7TM GPCR rhodopsin 0.0165 0.0467 0.1104
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus multilocularis sex peptide receptor 0.0165 0.0467 0.0467
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0034 0.0077
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0034 0.0348
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0165 0.0467 0.107
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0241 0.0696 0.7929
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0034 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0855 0.6197
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0399 0.4532
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0301 0.0877 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0241 0.1744
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0004 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0126 0.1397
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0084 0.2081
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0034 0.0077
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Brugia malayi Protein kinase domain containing protein 0.0038 0.0084 0.0193
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0143 0.0402 0.0921
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Schistosoma mansoni z-protein (S1r protein) 0.0237 0.0682 0.1564
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0389 0.114 0.2612
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0057 0.141
Echinococcus granulosus death domain containing protein 0.0032 0.0066 0.0156
Plasmodium falciparum phosphodiesterase delta, putative 0.0143 0.0402 1
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0143 0.0402 0.0402
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0022 0.0036 0.0884
Loa Loa (eye worm) syntrophin-1 0.0022 0.0036 0.0081
Schistosoma mansoni fibrocystin l 0.0012 0.0006 0.0014
Brugia malayi Plekhf2 protein 0.0022 0.0036 0.0081
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0221 0.0506
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0068 0.7691
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0214 0.0615 0.8939
Echinococcus granulosus nmda type glutamate receptor 0.0022 0.0036 0.0084
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0122 0.1671
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0163 0.0461 0.1057
Brugia malayi AMP-binding enzyme family protein 0.005 0.0122 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0191
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0022 0.0036 0.0415
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0131 0.0299
Brugia malayi ecdysteroid receptor 0.0021 0.0034 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi hypothetical protein 0.0022 0.0036 0.0081
Schistosoma mansoni opsin-like receptor 0.0165 0.0467 0.107
Loa Loa (eye worm) glutamate receptor 0.0232 0.0667 0.1528
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0142 0.0325
Echinococcus granulosus tar DNA binding protein 0.0062 0.0155 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Trypanosoma brucei unspecified product 0.0015 0.0014 0.0121
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus Ankyrin 0.0032 0.0067 0.0159
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0165 0.0467 0.107
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.4556
Loa Loa (eye worm) cytohesin 3 0.0022 0.0036 0.0081
Leishmania major hypothetical protein, conserved 0.0022 0.0036 0.0366
Echinococcus multilocularis Ras associated and pleckstrin y 0.0022 0.0036 0.0036
Brugia malayi hypothetical protein 0.0011 0.0004 0.0008
Brugia malayi 6-phosphofructokinase 0.0106 0.029 0.0664
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0049 0.0521
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0112 0.0308 0.0707
Echinococcus granulosus nuclear receptor nhr 48 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0118
Loa Loa (eye worm) AGC/AKT protein kinase 0.0028 0.0054 0.0123
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0022 0.0036 0.0036
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0143 0.0402 0.0402
Echinococcus multilocularis calcium dependent secretion activator 1 0.0022 0.0036 0.0036
Schistosoma mansoni coup transcription factor 0.0021 0.0034 0.0078
Echinococcus multilocularis allatostatin A receptor 0.0165 0.0467 0.0467
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0034 0.0348
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0083 0.0197
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0014 0.0088
Toxoplasma gondii protein kinase domain-containing protein 0.0028 0.0054 0.0153
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 0.2911
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0143 0.0402 0.095
Echinococcus multilocularis neuropeptide receptor A26 0.0165 0.0467 0.0467
Loa Loa (eye worm) oxysterol binding protein 0.0022 0.0036 0.0081
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0038 0.0083 0.0601
Brugia malayi Patched family protein 0.0013 0.0008 0.0019
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0028 0.0054 0.0578
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0143 0.0402 0.4556
Brugia malayi Dynamin 0.0022 0.0036 0.0081
Entamoeba histolytica PH domain containing protein 0.0022 0.0036 0.0415
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0004
Entamoeba histolytica PH domain containing protein kinase, putative 0.0028 0.0054 0.0632
Brugia malayi Probable exocyst complex component Sec5 0.0012 0.0006 0.0013
Echinococcus multilocularis regulator of G protein signaling 7 0.0237 0.0682 0.0682
Entamoeba histolytica protein kinase, putative 0.0028 0.0054 0.0632
Echinococcus multilocularis transient receptor potential cation channel 0.0169 0.0477 0.0477
Echinococcus multilocularis oxysterol binding protein 9 0.0022 0.0036 0.0036
Trypanosoma brucei protein kinase, putative 0.0057 0.0142 0.158
Onchocerca volvulus 0.0022 0.0036 0.0256
Plasmodium vivax glutathione reductase, putative 0.0094 0.0253 0.6296
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0065 0.0148
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0015 0.0033
Mycobacterium ulcerans hypothetical protein 0.005 0.0122 0.2479
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0102
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0285 0.0828 0.0828
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0165 0.0467 0.0467
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0448 0.6477
Toxoplasma gondii hypothetical protein 0.0085 0.0224 0.0636
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0057 0.5917
Brugia malayi plexin A 0.0077 0.0202 0.0462
Loa Loa (eye worm) galactosyltransferase 0.0048 0.0116 0.0265
Schistosoma mansoni goodpasture antigen-binding protein 0.0022 0.0036 0.0081
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0131 0.0299
Trypanosoma cruzi Protein kinase B 0.0028 0.0054 0.0578
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0034 0.0397
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0311 0.0906 0.0906
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0022 0.0036 0.0366
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0165 0.0467 0.1069
Brugia malayi nuclear receptor NHR-67 0.001 0 0.0000046864
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Echinococcus granulosus Pleckstrin y 0.0022 0.0036 0.0084
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1178 0.3514 0.8056
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0686 0.1623
Onchocerca volvulus 0.002 0.003 0.0214
Loa Loa (eye worm) PH domain-containing protein 0.0022 0.0036 0.0081
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0143 0.0402 0.092
Echinococcus granulosus serine/threonine protein kinase 0.0028 0.0054 0.0128
Brugia malayi Regulator of G protein signaling domain containing protein 0.0237 0.0682 0.1563
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0034 0.0246
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Onchocerca volvulus 0.0165 0.0467 0.3379
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.001 0 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0165 0.0467 0.107
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0015 0.0091
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0143 0.0402 0.1138
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0142 0.1026
Schistosoma mansoni GTP-binding protein alpha subunit 0.001 0 0.0001
Toxoplasma gondii hypothetical protein 0.0048 0.0116 0.0328
Schistosoma mansoni beta-14-galactosyltransferase 0.0029 0.0056 0.0129
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0029 0.0067
Trypanosoma cruzi hypothetical protein 0.0022 0.0036 0.0366
Loa Loa (eye worm) hypothetical protein 0.1178 0.3514 0.8056
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0022 0.0036 0.0081
Brugia malayi Receptor family ligand binding region containing protein 0.0059 0.0149 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.0682 0.4944
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Toxoplasma gondii hypothetical protein 0.0013 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0098 0.1078
Echinococcus granulosus dro:myosuppressin receptor 0.0165 0.0467 0.1104
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0036 0.0084
Brugia malayi hypothetical protein 0.0237 0.0682 0.1563
Trypanosoma brucei protein kinase, putative 0.0028 0.0054 0.0578
Plasmodium vivax PH domain containing protein 0.0022 0.0036 0.0884
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0143 0.0402 0.092
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1223 0.365 0.365
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0165 0.0467 0.107
Loa Loa (eye worm) hypothetical protein 0.0165 0.0467 0.1069
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0143 0.0402 0.095
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0014 0.0088
Schistosoma mansoni beta-14-galactosyltransferase 0.0048 0.0116 0.0265
Schistosoma mansoni phenylalanine decarboxylase 0.0048 0.0116 0.0265
Leishmania major folate/biopterin transporter, putative 0.0028 0.0054 0.0578
Entamoeba histolytica hypothetical protein 0.0113 0.031 0.3622
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0012 0.0006 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0155 0.0356
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0143 0.0402 1
Brugia malayi TAR-binding protein 0.0062 0.0155 0.0355
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0143 0.0402 0.0921
Echinococcus granulosus myotubularin protein 13 0.0022 0.0036 0.0084
Echinococcus multilocularis Niemann Pick C1 protein 0.0299 0.0871 0.0871
Leishmania major DNA polymerase eta, putative 0.0021 0.0034 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0257
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0014 0.0088
Echinococcus multilocularis expressed protein 0.0237 0.0682 0.0682
Brugia malayi hypothetical protein 0.0165 0.0467 0.1069
Brugia malayi A-kinase anchor protein 10, precursor 0.0237 0.0682 0.1563
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0068 0.0739
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0015 0.0004
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0096 0.0257 0.0609
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0004 0.001
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0015 0.0006
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0143 0.0402 0.4556
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.019
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.003 0.0071
Onchocerca volvulus 0.0027 0.0052 0.0374
Leishmania major mitochondrial DNA polymerase beta 0.0301 0.0877 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0165 0.0467 0.1104
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0054 0.0392
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1178 0.3514 0.3514
Brugia malayi hypothetical protein 0.0013 0.0008 0.0019
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0078 0.0564
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0022 0.0036 0.0036
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0142 0.158
Brugia malayi putative neuropeptide receptor NPR1 0.0165 0.0467 0.1069
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0 0.0001
Onchocerca volvulus 0.0065 0.0166 0.1199
Loa Loa (eye worm) PXA domain-containing protein 0.0237 0.0682 0.1563
Echinococcus granulosus Rho GTPase activating protein 24 0.0022 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0081
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0034 0.0034
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0196 0.0449
Trypanosoma cruzi PH domain containing protein, putative 0.0022 0.0036 0.0366
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0143 0.0402 0.2911
Loa Loa (eye worm) hypothetical protein 0.0285 0.0828 0.1897

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 0.64 Antagonist activity at CB2 receptor expressed in HEK293 cells assessed as blockade of secreted alkaline phosphatase activity at 1 uM after 6 hrs relative to control ChEMBL. 18077343
EC50 (functional) = -9.48 Negative logarithm of the molar concentration of delta receptor was determined in mouse vas deferens ChEMBL. 11133082
EC50 (binding) = 4.71 nM Agonist potency using GTP-gamma [35S]- binding assay for delta-opioid receptor ChEMBL. 11448220
EC50 (binding) = 1130 nM Agonist potency using GTP-gamma [35S]- binding assay for mu-opioid receptor ChEMBL. 11448220
Emax (binding) = 21.8 % Compound was tested for maximum stimulation of mu opioid receptor by GTP-gamma [35S]- binding assay ChEMBL. 11448220
Emax (binding) = 78.7 % Maximum stimulation of delta opioid receptor by GTP-gamma [35S]- binding assay ChEMBL. 11448220
Emax (functional) = 91 % Agonist activity at delta receptor as maximal effect induced by an agonist expressed as percent inhibition of the electrically induced twitches in rat vas deferens ChEMBL. 11133082
IC50 (binding) = 0.08 nM Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membrane by liquid scintillation counting ChEMBL. 22047797
IC50 (functional) = 0.21 nM The inhibitory concentration activity of the compound was measured on electrically induced contraction of the mouse vas deferens (MVD) ChEMBL. 9083489
IC50 (functional) = 0.39 nM inhibitory concentration for inhibition of electrically induced smooth muscle contractions of MVD (mouse vas deferens) myenteric-plexus-longitudinal muscle strips. ChEMBL. 10753473
IC50 (functional) = 0.53 nM Agonist activity at delta opioid receptor in mouse vas deference ChEMBL. 20637637
IC50 (functional) = 0.75 nM Concentration of the compound required to inhibit electrically induced twitch by 50% in mouse vas deferens(MVD). ChEMBL. 1335080
IC50 (binding) = 1.3 nM Binding affinity at cloned human delta-opioid receptor ChEMBL. 11448220
IC50 (binding) = 5.55 nM In vitro opioid receptor delta mediated mouse vas deferens (MVD) assay ChEMBL. 1851843
IC50 (binding) = 5.55 nM In vitro opioid receptor delta mediated mouse vas deferens (MVD) assay ChEMBL. 1851843
IC50 (binding) = 184 nM Displacement of [3H]-DSLET from delta opioid receptor in rat brain membrane ChEMBL. 1851843
IC50 (binding) = 184 nM Displacement of [3H]-DSLET from delta opioid receptor in rat brain membrane ChEMBL. 1851843
IC50 (binding) = 225 nM Binding affinity at cloned human mu-opioid receptor ChEMBL. 11448220
IC50 (functional) = 1000 nM inhibitory concentration for inhibition of electrically induced smooth muscle contractions of GPI (guinea pig ileum) myenteric-plexus-longitudinal muscle strips. ChEMBL. 10753473
IC50 (binding) = 7330 nM Binding affinity at cloned human opioid receptor kappa 1 ChEMBL. 11448220
IC50 (binding) = 9000 nM Inhibition of opioid receptor mu in guinea pig ileum (GPI) ChEMBL. 1851843
IC50 (binding) = 9000 nM Inhibition of opioid receptor mu in guinea pig ileum (GPI) ChEMBL. 1851843
IC50 (functional) > 10000 nM Agonist activity at mu opioid receptor in Hartley guinea pig small intestine ChEMBL. 20637637
IC50 (binding) = 14500 nM Displacement of [3H]- DAGO from opioid receptor mu in rat brain membrane ChEMBL. 1851843
IC50 (binding) = 14500 nM Displacement of [3H]- DAGO from opioid receptor mu in rat brain membrane ChEMBL. 1851843
Ke (functional) nM Affinity of the compound towards mu opioid receptor using CTAP as antagonist in guinea pig ileum; Not tested ChEMBL. 12657261
Ke (functional) = 0.64 nM Affinity of the compound towards delta opioid receptor using N,N(Me)2Dmt-Tic-OH as antagonist in mouse vas deferens ChEMBL. 12657261
Ke (functional) > 1000 nM Affinity of the compound towards delta opioid receptor using CTAP as antagonist in mouse vas deferens ChEMBL. 12657261
Ki (binding) = 0.12 nM Binding affinity against opioid receptor delta in rats by displacing [3H]-DPDPE ChEMBL. 1335080
Ki (binding) = 0.12 nM Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membrane ChEMBL. 20637637
Ki (binding) = 0.31 nM Inhibition of [3H]-DADLE binding to opioid receptor delta in P2 membrane preparation of rat brain ChEMBL. 1849997
Ki (binding) = 0.41 nM Inhibition of [3H]-DPDPE binding to Opioid receptor delta 1 ChEMBL. 1313878
Ki (binding) = 638 nM Binding affinity against opioid receptor mu in rats by displacing [3H]-DAGO ChEMBL. 1335080
Ki (binding) = 638 nM Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membrane ChEMBL. 20637637
Ki (binding) = 1280 nM Inhibition of [3H]-DAGO binding to trat brain opioid receptor mu in P2 membrane ChEMBL. 1849997
Ki (binding) = 1280 nM Inhibition of [3H]-DAGO binding to rat Opioid receptor mu 1 ChEMBL. 1313878
NA (binding) 0 Agonist potency using GTP-gamma [35S]- binding assay for opioid receptor kappa 1; Inactive ChEMBL. 11448220
Ratio (binding) = 1620 IC50 ratio of the compound is GPI/MVD ChEMBL. 1851843
Ratio (binding) = 78 Relative affinity for mu and delta opioid receptors in rat brain membrane ChEMBL. 1851843
Ratio (binding) = 173 Ratio, binding to cloned human mu-opioid versus delta-opioid receptor (IC50) ChEMBL. 11448220
Ratio (binding) = 1620 IC50 ratio of the compound is GPI/MVD ChEMBL. 1851843
Ratio (binding) = 5640 Ratio, binding to cloned human kappa-opioid versus delta-opioid receptor (IC50) ChEMBL. 11448220

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 1335080

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

7 literature references were collected for this gene.

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