Detailed information for compound 946233

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 467.968 | Formula: C24H22ClN3O3S
  • H donors: 2 H acceptors: 4 LogP: 4.64 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc2c(c1)c(c([nH]2)C(=O)NC(c1ccncc1)C)S(=O)(=O)c1cc(C)cc(c1)C
  • InChi: 1S/C24H22ClN3O3S/c1-14-10-15(2)12-19(11-14)32(30,31)23-20-13-18(25)4-5-21(20)28-22(23)24(29)27-16(3)17-6-8-26-9-7-17/h4-13,16,28H,1-3H3,(H,27,29)
  • InChiKey: WOULWISOHTZRJX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Reverse transcriptase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni hypothetical protein Get druggable targets OG5_139608 All targets in OG5_139608
Trypanosoma brucei RNA helicase, putative Get druggable targets OG5_139608 All targets in OG5_139608
Trypanosoma congolense RNA helicase, putative Get druggable targets OG5_139608 All targets in OG5_139608
Plasmodium yoelii integrase-related Get druggable targets OG5_139608 All targets in OG5_139608
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) Reverse transcriptase   259 aa 208 aa 26.4 %
Dictyostelium discoideum hypothetical protein Reverse transcriptase   259 aa 245 aa 25.7 %
Trypanosoma congolense Retroviral aspartyl protease/Reverse transcriptase (RNA-dependent DNA polymerase)/RNase H, putative Reverse transcriptase   259 aa 237 aa 29.1 %
Dictyostelium discoideum hypothetical protein Reverse transcriptase   259 aa 222 aa 22.5 %
Dictyostelium discoideum hypothetical protein Reverse transcriptase   259 aa 226 aa 24.3 %
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) Reverse transcriptase   259 aa 227 aa 26.4 %
Candida albicans ReverseTranscriptase similar to fruit fly Tom element Reverse transcriptase   259 aa 244 aa 27.9 %
Candida albicans hypothetical protein Reverse transcriptase   259 aa 223 aa 29.1 %
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) Reverse transcriptase   259 aa 227 aa 26.4 %
Candida albicans polyprotein of retrotransposon Tca8 Reverse transcriptase   259 aa 238 aa 26.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0068 0.007 0.0816
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0019 0.0005 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0023 0.001 0.0188
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0024 0.0024
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0397 0.0506 0.4759
Echinococcus granulosus chromobox protein 2 0.0024 0.0012 0.0018
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0088 0.0283
Loa Loa (eye worm) dihydrofolate reductase 0.0029 0.0018 0.0057
Echinococcus multilocularis inositol monophosphatase 1 0.0062 0.0062 0.0062
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0009 0.0008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0055 0.0052 0.0168
Loa Loa (eye worm) transcription factor SMAD2 0.1689 0.2217 0.7176
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0513 0.066 0.2134
Brugia malayi CHD4 protein 0.0037 0.0029 0.0093
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0418 0.0533 0.0849
Loa Loa (eye worm) hypothetical protein 0.006 0.0059 0.0191
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0091 0.0091
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0094 0.0586
Entamoeba histolytica peptidase, C54 family 0.0026 0.0014 0.0238
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0012 0.0012
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0005 0.0008
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0024 0.0038
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0024 0.0077
Schistosoma mansoni opsin-like receptor 0.0033 0.0024 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0025 0.0039
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0104 0.0118 0.0388
Onchocerca volvulus 0.0024 0.0012 0.0036
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0062 0.0199
Loa Loa (eye worm) hypothetical protein 0.019 0.0232 0.0751
Brugia malayi Serotonin receptor 0.0033 0.0024 0.0077
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0004 0.0003
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0063 0.0064 0.0101
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0029 0.0018 0.011
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0055 0.0052 0.0994
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0024 0.0024
Trichomonas vaginalis esterase, putative 0.019 0.0232 0.2746
Brugia malayi Bromodomain containing protein 0.0082 0.0089 0.0286
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0029 0.0045
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Brugia malayi HSF-type DNA-binding domain containing protein 0.0104 0.0118 0.0381
Trypanosoma brucei glucosidase, putative 0.0041 0.0034 0.0108
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.001 0.0093
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0019 0.0118
Schistosoma mansoni myst-related protein 0.0025 0.0013 0.002
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0055 0.0052 0.0168
Loa Loa (eye worm) helicase 0.0024 0.0012 0.0038
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0025 0.0024
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Leishmania major hypothetical protein, conserved 0.019 0.0232 0.075
Leishmania major cathepsin L-like protease 0.0102 0.0115 0.037
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0051 0.0048 0.0047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0024 0.0038
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.031 0.0391 0.0621
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.0698
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0397 0.0506 0.0805
Onchocerca volvulus 0.0033 0.0024 0.0077
Echinococcus granulosus transcription factor Dp 1 0.004 0.0032 0.0051
Echinococcus granulosus g protein coupled receptor 0.0033 0.0024 0.0038
Entamoeba histolytica hypothetical protein, conserved 0.0182 0.0221 0.4338
Onchocerca volvulus 0.0033 0.0024 0.0077
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0397 0.0506 0.1637
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0025 0.0079
Schistosoma mansoni chromobox protein 0.0147 0.0175 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0043 0.0491
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0043 0.0036 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0148 0.0235
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0032 0.0023 0.0023
Trypanosoma brucei polo-like protein kinase 0.0061 0.006 0.0194
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0019 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0004 0.0006
Leishmania major cytochrome p450-like protein 0.0028 0.0017 0.0055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0028 0.0091
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis fk506-binding protein, putative 0.0055 0.0052 0.0598
Toxoplasma gondii cathepsin CPL 0.0029 0.0019 0.0173
Brugia malayi SET domain containing protein 0.002 0.0007 0.0021
Brugia malayi follicle stimulating hormone receptor 0.0262 0.0327 0.1058
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.004 0.0033 0.0105
Entamoeba histolytica heat shock transcription factor, putative 0.0104 0.0118 0.2301
Brugia malayi Cathepsin L-like precursor 0.0029 0.0019 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Toxoplasma gondii Sel1 repeat-containing protein 0.0023 0.001 0.0089
Brugia malayi steroid hormone receptor 0.0034 0.0025 0.0079
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0045 0.0039 0.0739
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0055 0.0052 0.0489
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0045 0.0039 0.1665
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0513 0.066 0.2134
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0019 0.0061
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0045 0.0039 0.0062
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0066 0.0068 0.0784
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.0015
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0091 0.0295
Trypanosoma cruzi Sel1 repeat, putative 0.0023 0.001 0.0031
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0397 0.0506 0.6016
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0034 0.0108
Brugia malayi MAP kinase sur-1 0.0084 0.0091 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Trypanosoma brucei cysteine peptidase C (CPC) 0.0044 0.0038 0.0123
Trypanosoma cruzi major cysteine proteinase, putative 0.0081 0.0087 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Schistosoma mansoni aldehyde dehydrogenase 0.0045 0.0039 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0062 0.0062 0.0713
Trichomonas vaginalis TK family protein kinase 0.0025 0.0013 0.0124
Brugia malayi MHCK/EF2 kinase domain family protein 0.0623 0.0805 0.2606
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0021
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.004 0.0033 0.0306
Plasmodium vivax vivapain-2 0.0029 0.0019 0.0364
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0019 0.0005 0.0005
Schistosoma mansoni smad 0.0115 0.0132 0.0211
Onchocerca volvulus 0.019 0.0232 0.0766
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0024 0.0078
Schistosoma mansoni survival motor neuron protein 0.0128 0.0149 0.0237
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0106 0.0666
Plasmodium falciparum importin beta, putative 0.0054 0.0052 0.1017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0043 0.0036 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0446 0.057 0.0907
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0017 0.0055
Trypanosoma brucei C-8 sterol isomerase, putative 0.2347 0.309 1
Schistosoma mansoni ap endonuclease 0.0043 0.0036 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0017 0.0107
Toxoplasma gondii HEAT repeat-containing protein 0.0054 0.0052 0.0484
Brugia malayi AKH receptor 0.0033 0.0024 0.0077
Mycobacterium ulcerans hypothetical protein 0.019 0.0232 0.2179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0017 0.0002 0.0012
Plasmodium vivax ataxin-2 like protein, putative 0.0082 0.0089 0.1752
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0009 0.0008
Echinococcus multilocularis sodium and chloride dependent glycine 0.0071 0.0074 0.0074
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0024 0.0038
Toxoplasma gondii hypothetical protein 0.0083 0.0089 0.084
Brugia malayi AMP-binding enzyme family protein 0.005 0.0046 0.0149
Echinococcus granulosus inositol monophosphatase 1 0.0062 0.0062 0.0098
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.005 0.0046 0.015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus granulosus chromobox protein 1 0.0147 0.0175 0.0278
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.003 0.0582
Loa Loa (eye worm) hypothetical protein 0.019 0.0232 0.0751
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.019 0.0232 0.2179
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0019 0.0005 0.0008
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.0994
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1216 0.1591 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0054 0.0052 0.0166
Onchocerca volvulus 0.0033 0.0024 0.0077
Mycobacterium ulcerans aldehyde dehydrogenase 0.0817 0.1062 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0025 0.0079
Leishmania major elongation factor-2 kinase-like protein 0.0182 0.0221 0.0713
Onchocerca volvulus 0.002 0.0007 0.0019
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0022 0.0009 0.0013
Schistosoma mansoni gabp alpha 0.0053 0.005 0.0079
Echinococcus multilocularis expressed protein 0.0019 0.0005 0.0005
Echinococcus multilocularis microtubule associated protein 2 0.4755 0.6282 0.6282
Mycobacterium tuberculosis Conserved protein 0.019 0.0232 0.1457
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0055 0.0052 0.0327
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0093 0.0299
Echinococcus granulosus integrin beta 2 0.0652 0.0844 0.1343
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0012 0.0038
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0019 0.0059
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.0232 0.2746
Schistosoma mansoni cathepsin D (A01 family) 0.0061 0.0061 0.0097
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0057 0.0056
Echinococcus multilocularis serine protein kinase ATM 0.0021 0.0007 0.0007
Echinococcus multilocularis cathepsin L 0.0017 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0046 0.0429
Plasmodium falciparum cysteine protease ATG4, putative 0.0026 0.0014 0.0274
Brugia malayi intermediate filament protein 0.0193 0.0236 0.0762
Schistosoma mansoni biogenic amine receptor 0.0033 0.0024 0.0038
Schistosoma mansoni integrin beta subunit 0.0518 0.0666 0.1061
Echinococcus granulosus allatostatin A receptor 0.0033 0.0024 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Schistosoma mansoni zinc finger protein 0.0016 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0045 0.0039 0.0063
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0017 0.0002 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Brugia malayi Pyruvate kinase, M2 isozyme 0.0029 0.0018 0.0058
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Onchocerca volvulus Matrilysin homolog 0.0189 0.023 0.0761
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.003 0.0184
Loa Loa (eye worm) hypothetical protein 0.0459 0.0588 0.1903
Trypanosoma cruzi Sel1 repeat, putative 0.0023 0.001 0.0031
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0001 0.0001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0033 0.0107
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0024 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Brugia malayi larval opioid receptor 0.0033 0.0024 0.0077
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0024 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Mycobacterium ulcerans ion transport protein 0.0337 0.0426 0.4006
Onchocerca volvulus 0.0033 0.0024 0.0077
Brugia malayi mbt repeat family protein 0.0045 0.0039 0.0127
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0094 0.0586
Loa Loa (eye worm) Sel1l protein 0.0023 0.001 0.0032
Plasmodium falciparum cysteine proteinase falcipain 1 0.0017 0.0002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0048 0.0043 0.0396
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Echinococcus granulosus dnaJ subfamily B 0.2784 0.3669 0.5841
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0033 0.0053
Toxoplasma gondii cathepsin B 0.0044 0.0038 0.0359
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.0241
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0033 0.0033
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0016 0.0002 0.0006
Echinococcus granulosus Peptidase C54 0.0066 0.0068 0.0107
Schistosoma mansoni Smad4 0.0051 0.0048 0.0076
Brugia malayi MH1 domain containing protein 0.0064 0.0064 0.0207
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0057 0.0089
Plasmodium falciparum plasmepsin IV 0.0021 0.0007 0.0139
Brugia malayi Ets-domain containing protein 0.0053 0.005 0.016
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.004 0.0033 0.0105
Brugia malayi nuclear hormone receptor 0.0034 0.0025 0.0079
Echinococcus granulosus expressed protein 0.0019 0.0005 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Toxoplasma gondii thioredoxin reductase 0.0038 0.003 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0025 0.0079
Echinococcus multilocularis tar DNA binding protein 0.0127 0.0148 0.0147
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0019 0.0005 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Schistosoma mansoni immunophilin 0.0397 0.0506 0.0805
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0243 0.0302 0.0975
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0025 0.0024
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0045 0.0039 0.0062
Schistosoma mansoni sel-1-like protein sel-1l 0.0023 0.001 0.0016
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0045 0.0039 0.0127
Entamoeba histolytica protein kinase, putative 0.0182 0.0221 0.4338
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0024 0.0024
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0024 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0057 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0013 0.0124
Echinococcus multilocularis Smad4 0.0115 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0026 0.0014 0.0045
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0397 0.0506 1
Entamoeba histolytica hypothetical protein 0.0044 0.0038 0.0714
Brugia malayi Phospholipase A2 family protein 0.0104 0.0117 0.0378
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Schistosoma mansoni aldehyde dehydrogenase 0.0045 0.0039 0.0063
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0105
Echinococcus granulosus sodium and chloride dependent glycine 0.0071 0.0074 0.0118
Brugia malayi chromobox protein homolog 3 0.0083 0.0089 0.0288
Brugia malayi AMP-binding enzyme family protein 0.005 0.0046 0.0149
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0019 0.0005 0.0016
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0017 0.0154
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0022 0.0009 0.0165
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0342 0.0433 0.069
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0046 0.1968
Onchocerca volvulus 0.0033 0.0024 0.0077
Toxoplasma gondii Sel1 repeat-containing protein 0.0023 0.001 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0034 0.0377
Entamoeba histolytica G protein alpha subunit, putative 0.0019 0.0005 0.0061
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0344 0.0436 0.0694
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Loa Loa (eye worm) hypothetical protein 0.0083 0.0089 0.0289
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0016 0.0002 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0046 0.0878
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Trichomonas vaginalis ran, putative 0.004 0.0033 0.0365
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0071 0.0074 0.0118
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0397 0.0506 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0012 0.0019
Brugia malayi hypothetical protein 0.0024 0.0012 0.0037
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0196
Schistosoma mansoni bromodomain containing protein 0.0071 0.0074 0.0118
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0066 0.0068 0.0108
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0019 0.0005 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0017 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0019 0.0005 0.0036
Brugia malayi Niemann-Pick C1 protein precursor 0.0114 0.013 0.0421
Giardia lamblia DINP protein human, muc B family 0.0019 0.0005 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0074 0.0238
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0019 0.0005 0.0016
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0074 0.0117
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0019 0.0005 0.0008
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0033 0.0107
Brugia malayi Melatonin receptor type 1A 0.0033 0.0024 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0045 0.0039 0.0063
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0045 0.0039 0.0363
Echinococcus multilocularis survival motor neuron protein 1 0.0626 0.081 0.0809
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0019 0.0005 0.0008
Loa Loa (eye worm) integrin beta-2 0.088 0.1146 0.3708
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0021 0.0007 0.0024
Schistosoma mansoni immunophilin 0.0397 0.0506 0.0805
Plasmodium vivax amine transporter, putative 0.0071 0.0074 0.1466
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0017 0.0154
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0089 0.0098 0.0155
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0446 0.057 0.057
Loa Loa (eye worm) hypothetical protein 0.005 0.0046 0.015
Trichomonas vaginalis glutaminase, putative 0.0208 0.0256 0.3033
Trichomonas vaginalis CAMK family protein kinase 0.003 0.002 0.0215
Plasmodium falciparum ubiquitin-protein ligase, putative 0.0023 0.001 0.0188
Onchocerca volvulus 0.0029 0.0019 0.0059
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0071 0.0227
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0012 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0013 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0052 0.0598
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0262 0.0328 0.106
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0009
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.0048 0.0155
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0397 0.0506 1
Echinococcus granulosus dna polymerase eta 0.0019 0.0005 0.0007
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0033 0.0024 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0002 0.0006
Echinococcus multilocularis cysteine protease atg4b 0.0066 0.0068 0.0067
Brugia malayi Ets-domain containing protein 0.0053 0.005 0.016
Echinococcus granulosus sex peptide receptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) MH1 domain-containing protein 0.0115 0.0132 0.0428
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0052 0.0048 0.0048
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0045 0.0039 0.0062
Schistosoma mansoni protein kinase 0.0156 0.0187 0.0297
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0063 0.0064 0.0064
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0093 0.0103 0.0103
Brugia malayi EGF-like domain containing protein 0.0028 0.0017 0.0055
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0024 0.0024
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0025 0.0039
Brugia malayi Matrixin family protein 0.0085 0.0093 0.0299
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0024 0.0078
Echinococcus granulosus survival motor neuron protein 1 0.0626 0.081 0.1288
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0019 0.0005 0.0008
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0017 0.0154
Echinococcus multilocularis tumor protein p63 0.1107 0.1447 0.1447
Entamoeba histolytica hypothetical protein 0.0197 0.0241 0.4738
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0019 0.0005 0.0008
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0044 0.0044
Plasmodium falciparum ubiquitin-protein ligase, putative 0.0023 0.001 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0025 0.0079
Echinococcus granulosus sodium and chloride dependent glycine 0.0071 0.0074 0.0118
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0029 0.0018 0.0727
Schistosoma mansoni vesicular amine transporter 0.0016 0.0001 0.0002
Echinococcus granulosus cathepsin L cysteine proteinase 0.0029 0.0019 0.0029
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0016 0.0001 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0068 0.007 0.0816
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0071 0.0074 0.0074
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0071 0.0227
Leishmania major myosin heavy chain kinase c-like protein 0.0182 0.0221 0.0713
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0115 0.0133 0.0211
Echinococcus multilocularis GA binding protein alpha chain 0.0053 0.005 0.005
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0012 0.0118
Echinococcus multilocularis pyruvate kinase 0.0029 0.0018 0.0018
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0089 0.0287
Brugia malayi glutaminase DH11.1 0.0208 0.0256 0.0828
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0021 0.0007 0.0062
Echinococcus granulosus fetal alzheimer antigen falz 0.0032 0.0023 0.0036
Schistosoma mansoni zinc finger protein 0.003 0.0019 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0017 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0055 0.0052 0.0083
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0046 0.1968
Onchocerca volvulus 0.0019 0.0005 0.0014
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0051 0.0048 0.0156
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Onchocerca volvulus 0.0128 0.0149 0.0491
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0056
Onchocerca volvulus 0.0034 0.0025 0.0079
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0033 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0025 0.0013 0.0124
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0053 0.005 0.047
Loa Loa (eye worm) pyruvate kinase-PB 0.002 0.0007 0.0021
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0017 0.0017
Toxoplasma gondii melibiase subfamily protein 0.0089 0.0098 0.0916
Loa Loa (eye worm) G protein alpha subunit 3 0.0019 0.0005 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0004 0.0011
Brugia malayi isocitrate dehydrogenase 0.0022 0.0009 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0025 0.0079
Brugia malayi neuropeptide F receptor 0.0033 0.0024 0.0077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0024 0.0024
Brugia malayi RNA, U transporter 1 0.0154 0.0184 0.0595
Loa Loa (eye worm) hypothetical protein 0.2347 0.309 1
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0024 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.083 0.1079 0.3492
Onchocerca volvulus 0.0029 0.0019 0.0059
Loa Loa (eye worm) prolyl oligopeptidase 0.0158 0.0189 0.0612
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0045 0.0039 0.0039
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0001 0.0002
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0342 0.0433 0.0433
Brugia malayi MH2 domain containing protein 0.0115 0.0132 0.0427
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0018 0.0057
Loa Loa (eye worm) MBCTL1 0.0051 0.0048 0.0154
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0025 0.0039
Giardia lamblia Cathepsin B precursor 0.0044 0.0038 0.0678
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0043 0.0036 0.0117
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0098 0.1139
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0091 0.0145
Schistosoma mansoni chromobox protein 0.0147 0.0175 0.0278
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0025 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Schistosoma mansoni DNA polymerase eta 0.0019 0.0005 0.0008
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0397 0.0506 0.1636
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0158 0.0189 0.0189
Loa Loa (eye worm) glutathione reductase 0.0038 0.003 0.0096
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0025 0.0039
Echinococcus granulosus g protein coupled receptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Schistosoma mansoni hypothetical protein 0.2784 0.3669 0.5841
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.001 0.0032
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0071 0.0228
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0089 0.0098 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0007 0.0063
Onchocerca volvulus 0.011 0.0125 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0011 0.0106
Leishmania major hypothetical protein, conserved 0.0082 0.0089 0.0287
Brugia malayi Smad1 0.0115 0.0132 0.0427
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0019 0.0004 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0026 0.0014 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0262 0.0328 0.1061
Loa Loa (eye worm) hypothetical protein 0.0054 0.0052 0.0167
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0071 0.0227
Echinococcus granulosus neuropeptide receptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0064 0.0064 0.0208
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0019 0.0005 0.0008
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0012 0.0191
Brugia malayi hypothetical protein 0.0071 0.0074 0.024
Brugia malayi Cytochrome P450 family protein 0.0028 0.0017 0.0055
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0045 0.0039 0.0363
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0017 0.0154
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0045 0.0039 0.1665
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0024 0.0038
Trypanosoma brucei Sel1 repeat, putative 0.0023 0.001 0.0031
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0045 0.0039 0.0246
Loa Loa (eye worm) CYP4Cod1 0.0048 0.0043 0.0139
Brugia malayi Cathepsin L-like precursor 0.0029 0.0019 0.006
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.001 0.0093
Echinococcus granulosus tar DNA binding protein 0.0127 0.0148 0.0235
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.011 0.0125 0.0199
Loa Loa (eye worm) hypothetical protein 0.0085 0.0093 0.03
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0022 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0045 0.0039 0.0363
Echinococcus multilocularis snurportin 1 0.0579 0.0747 0.0747
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0085 0.0093 0.0093
Brugia malayi nuclear hormone receptor 0.0016 0.0001 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0012 0.0019
Loa Loa (eye worm) hypothetical protein 0.0506 0.0651 0.2106
Echinococcus multilocularis zinc finger protein 0.003 0.0019 0.0019
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0024 0.0038
Echinococcus granulosus cathepsin l1 0.0029 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.004 0.0033 0.0642
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0017 0.0107
Trichomonas vaginalis helicase, putative 0.0044 0.0039 0.0434
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0124 0.0144 0.023
Echinococcus granulosus neuropeptide s receptor 0.1017 0.1327 0.2112
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.001 0.0088
Loa Loa (eye worm) hypothetical protein 0.0459 0.0588 0.1903
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0018 0.0059
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0019 0.0005 0.0008
Echinococcus multilocularis serotonin receptor 0.0033 0.0024 0.0024
Echinococcus granulosus zinc finger protein 0.003 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0012
Brugia malayi Pyruvate kinase, muscle isozyme 0.0029 0.0018 0.0058
Echinococcus multilocularis beta LACTamase domain containing family member 0.019 0.0232 0.0232
Toxoplasma gondii isocitrate dehydrogenase 0.0022 0.0009 0.0078
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0045 0.0039 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Schistosoma mansoni hypothetical protein 0.0121 0.014 0.0223
Schistosoma mansoni amine GPCR 0.0033 0.0024 0.0038
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0024 0.0024
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0005 0.0056
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0045 0.0039 0.0246
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0089 0.1719
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0055 0.0052 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Leishmania major cathepsin L-like protease 0.0102 0.0115 0.037
Brugia malayi glutathione reductase 0.0038 0.003 0.0095
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0045 0.0039 0.0246
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0017 0.0107
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0817 0.1062 0.6672
Leishmania major peptidylprolyl isomerase-like protein 0.0397 0.0506 0.1636
Onchocerca volvulus 0.0029 0.0019 0.0059
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0359 0.7088
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0148 0.0235
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0045 0.0039 0.0739
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0033 0.058
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0005 0.0036
Echinococcus granulosus cathepsin b 0.0124 0.0144 0.0229
Schistosoma mansoni hypothetical protein 0.0055 0.0052 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0091 0.0146
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Schistosoma mansoni alpha glucosidase 0.0041 0.0034 0.0054
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0009 0.0027
Brugia malayi Muscleblind-like protein 0.0459 0.0588 0.1902
Trichomonas vaginalis inositol monophosphatase, putative 0.0062 0.0062 0.0713
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Echinococcus multilocularis isocitrate dehydrogenase 0.0022 0.0009 0.0008
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0024 0.0038
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0397 0.0506 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0024 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0025 0.0079
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0045 0.0039 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0024 0.0038
Brugia malayi serine/threonine-protein kinase plk-2 0.0061 0.006 0.0194
Toxoplasma gondii exonuclease III APE 0.0043 0.0036 0.034
Trypanosoma brucei myosin heavy chain kinase A, putative 0.0623 0.0805 0.2606
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0066 0.0068 0.0218
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0025 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Brugia malayi Cytochrome P450 family protein 0.0085 0.0093 0.0299
Onchocerca volvulus Cytochrome c oxidase assembly factor 7 homolog 0.0023 0.001 0.0029
Trichomonas vaginalis chromobox protein, putative 0.0147 0.0175 0.2063
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0262 0.0328 0.0521
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0024 0.0038
Schistosoma mansoni cytochrome P450 0.0028 0.0017 0.0027
Leishmania major GTP-binding protein, putative 0.004 0.0033 0.0105
Leishmania major myosin heavy chain kinase a-like protein 0.0623 0.0805 0.2606
Giardia lamblia Neurogenic locus notch-like protein 0.0028 0.0017 0.026
Mycobacterium tuberculosis Conserved protein 0.0024 0.0012 0.0074
Onchocerca volvulus 0.0019 0.0005 0.0014
Leishmania major aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Entamoeba histolytica actin binding protein, putative 0.0023 0.001 0.0151
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0024 0.0024
Echinococcus multilocularis adam 0.0028 0.0017 0.0017
Onchocerca volvulus 0.0019 0.0005 0.0014
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0017 0.0154
Brugia malayi Dopamine receptor protein 1 0.0033 0.0024 0.0077
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0024 0.0078
Schistosoma mansoni cellular tumor antigen P53 0.0162 0.0195 0.031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0025 0.0079
Plasmodium vivax importin-beta 2, putative 0.0054 0.0052 0.1017
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0026 0.0014 0.013
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0061 0.006 0.0096
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0001 0.0002
Brugia malayi prolyl oligopeptidase family protein 0.0053 0.005 0.0162
Loa Loa (eye worm) FKBP5 protein 0.0397 0.0506 0.1637
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0089 0.0287
Schistosoma mansoni pyruvate kinase 0.0029 0.0018 0.0029
Echinococcus multilocularis 0.0055 0.0052 0.0052
Entamoeba histolytica protein kinase, putative 0.0182 0.0221 0.4338
Leishmania major alpha glucosidase II subunit, putative 0.0041 0.0034 0.0108
Brugia malayi thymidylate synthase 0.007 0.0073 0.0234
Schistosoma mansoni myosin xvIII 0.0033 0.0024 0.0038
Brugia malayi Dopamine receptor 0.0033 0.0024 0.0077
Entamoeba histolytica peptidase, C54 family 0.0026 0.0014 0.0238
Mycobacterium ulcerans aldehyde dehydrogenase 0.0817 0.1062 1
Brugia malayi Intermediate filament tail domain containing protein 0.0193 0.0236 0.0762
Onchocerca volvulus 0.007 0.0073 0.0238
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0002 0.0004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0062 0.0062 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0088 0.0139
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0062 0.0062 0.0575
Brugia malayi hypothetical protein 0.0197 0.0241 0.0778
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0024 0.0038
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0012 0.0037
Echinococcus multilocularis lysosomal alpha glucosidase 0.0183 0.0223 0.0222
Brugia malayi mothers against decapentaplegic homolog 3 0.0051 0.0048 0.0154
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0025 0.0079
Plasmodium vivax unspecified product 0.0017 0.0002 0.0037
Loa Loa (eye worm) serotonin transporter b 0.042 0.0537 0.1737
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0099 0.0111 0.0357
Onchocerca volvulus 0.0121 0.014 0.0461
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0045 0.0039 0.0127
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0017
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0006 0.0019
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.003 0.003
Schistosoma mansoni ran 0.004 0.0033 0.0052
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0021 0.0007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0193 0.0236 0.0763
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0046 0.0429
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0017
Brugia malayi G-protein alpha subunit 0.0019 0.0005 0.0016
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0012 0.0115
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0045 0.0039 0.0363
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0001 0.0002
Echinococcus granulosus somatostatin receptor 0.0033 0.0024 0.0038
Trypanosoma brucei protein kinase, putative 0.0084 0.0091 0.0295
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0106 0.4556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0068 0.007 0.0816
Leishmania major cathepsin L-like protease 0.0029 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0128
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0024 0.0077
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0043 0.0036 0.0335
Schistosoma mansoni biogenic amine receptor 0.0033 0.0024 0.0038
Echinococcus multilocularis protein dispatched 1 0.0056 0.0054 0.0053
Leishmania major trypanothione reductase 0.0038 0.003 0.0095
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Echinococcus multilocularis protein tyrosine kinase 0.0249 0.0309 0.0309
Schistosoma mansoni hypothetical protein 0.0128 0.0149 0.0237
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Mycobacterium tuberculosis Conserved protein 0.019 0.0232 0.1457
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0068 0.007 0.0816
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0071 0.0112
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0025 0.0079
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0024 0.0024
Onchocerca volvulus 0.0071 0.0074 0.0243
Echinococcus granulosus cpg binding protein 0.0208 0.0256 0.0407
Onchocerca volvulus 0.0033 0.0024 0.0077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0027 0.0167
Entamoeba histolytica peptidase, C54 family 0.0026 0.0014 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Schistosoma mansoni amine GPCR 0.0033 0.0024 0.0038
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0024 0.0024
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0005 0.0036
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.024
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0159
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0062 0.0199
Brugia malayi nuclear receptor NHR-67 0.0016 0.0001 0.0002
Onchocerca volvulus 0.0024 0.0012 0.0036
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0071 0.0074 0.0074
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0021 0.0007 0.0023
Loa Loa (eye worm) solute carrier family 6 member 4 0.042 0.0537 0.1737
Trichomonas vaginalis chromobox protein, putative 0.0147 0.0175 0.2063
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0051 0.0048 0.0075
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0033 0.0107
Trypanosoma cruzi cysteine peptidase, putative 0.0102 0.0115 0.037
Brugia malayi G protein-coupled receptor 0.0033 0.0024 0.0077
Schistosoma mansoni GTP-binding protein alpha subunit 0.0019 0.0005 0.0008
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0071 0.0227
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0085 0.0093 0.0148
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0055 0.0052 0.0168
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0017 0.0055
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0055 0.0053 0.2266
Schistosoma mansoni patched 1 0.0049 0.0044 0.0071
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0016 0.0002 0.0008
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0017 0.0055
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0056
Schistosoma mansoni hypothetical protein 0.0033 0.0024 0.0038
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0007 0.0063
Trypanosoma cruzi pyruvate kinase 2, putative 0.0029 0.0018 0.0058
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0052 0.0048 0.0076
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0001 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.083 0.1079 0.3493
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.0109
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0088 0.0087
Leishmania major aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0019 0.0059
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0046 0.0878
Mycobacterium ulcerans beta-lactamase 0.019 0.0232 0.2179
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0034 0.0108
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0017 0.0107
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0001 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0027 0.0167
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.003 0.058
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0024 0.0024
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.001 0.0062
Brugia malayi hypothetical protein 0.0506 0.0651 0.2105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0068 0.007 0.0816
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0021 0.0033
Echinococcus multilocularis fk506 binding protein 0.0397 0.0506 0.0506
Brugia malayi CHE-14 protein 0.0049 0.0044 0.0143
Entamoeba histolytica protein kinase, putative 0.0024 0.0011 0.0176
Schistosoma mansoni histamine h1 receptor 0.0033 0.0024 0.0038
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0186 0.0226 0.0359
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0033 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0002 0.0006
Brugia malayi Dihydrofolate reductase 0.0029 0.0018 0.0056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0025 0.0039
Brugia malayi Cathepsin L-like precursor 0.0029 0.0019 0.006
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.0698
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0029 0.0019 0.0061
Onchocerca volvulus 0.0071 0.0074 0.0243
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Brugia malayi Cathepsin L-like precursor 0.0021 0.0007 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Echinococcus granulosus geminin 0.1405 0.1842 0.2932
Trypanosoma brucei ISWI complex protein 0.0021 0.0007 0.0022
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0158 0.0189 0.0301
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0046 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0048 0.0043 0.0491
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0071 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Brugia malayi mbt repeat family protein 0.0045 0.0039 0.0127
Plasmodium falciparum transporter, putative 0.0071 0.0074 0.1466
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0024 0.0077
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0151
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0017 0.0154
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0091 0.0295
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0025 0.0079
Onchocerca volvulus 0.0033 0.0024 0.0077
Echinococcus multilocularis histone acetyltransferase MYST2 0.0051 0.0048 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.1689 0.2217 0.7176
Loa Loa (eye worm) hypothetical protein 0.0039 0.0031 0.01
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0043 0.0036 0.0117
Brugia malayi EGF-like domain containing protein 0.0028 0.0017 0.0055
Schistosoma mansoni elongation factor 2 kinase 0.0182 0.0221 0.0351
Trichomonas vaginalis sucrase-isomaltase, putative 0.0041 0.0034 0.0377
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0359 0.7088
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0005 0.0034
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0017 0.0107
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0044 0.0038 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0012
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0104 0.0117 0.0379
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0012 0.0115
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0045 0.0039 0.0363
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0018 0.0057
Onchocerca volvulus 0.005 0.0046 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0053 0.005 0.0162
Mycobacterium leprae conserved hypothetical protein 0.0023 0.001 0.0402
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0002 0.0006
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0072 0.0075 0.0243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0024
Echinococcus granulosus mothers against decapentaplegic 5 0.0115 0.0132 0.021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0026 0.0014 0.0045
Brugia malayi MH1 domain containing protein 0.0115 0.0132 0.0427
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0089 0.1752
Loa Loa (eye worm) pigment dispersing factor receptor c 0.083 0.1079 0.3493
Schistosoma mansoni hypothetical protein 0.0579 0.0747 0.1189
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0089 0.0098 0.0155
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0024 0.0077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0034 0.0377
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0017 0.0154
Brugia malayi nuclear receptor NHR-88 0.0034 0.0025 0.0079
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Schistosoma mansoni cpg binding protein 0.0208 0.0256 0.0408
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0017 0.0107
Brugia malayi nuclear receptor RXR 0.0018 0.0004 0.0011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0262 0.0328 0.1061
Brugia malayi Peptidase family C54 containing protein 0.0066 0.0068 0.0218
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0055 0.0052 0.0052
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0044 0.0038 0.0432
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0044 0.0144
Trypanosoma cruzi cytochrome P450, putative 0.0048 0.0043 0.0138
Echinococcus granulosus thymidylate synthase 0.007 0.0073 0.0115
Onchocerca volvulus 0.019 0.0232 0.0766
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Echinococcus granulosus serotonin receptor 0.0033 0.0024 0.0038
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0005
Onchocerca volvulus 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0124 0.0144 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0817 0.1062 0.3436
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0091 0.1066
Onchocerca volvulus Fatty acid synthase homolog 0.0029 0.0018 0.0056
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0019 0.0005 0.0016
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0004 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0034 0.0627
Toxoplasma gondii aldehyde dehydrogenase 0.0817 0.1062 1
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0045 0.0039 0.0127
Loa Loa (eye worm) cytochrome P450 0.0028 0.0017 0.0056
Leishmania major fk506-binding protein 1-like protein 0.0397 0.0506 0.1636
Trypanosoma cruzi cytochrome P450, putative 0.0048 0.0043 0.0138
Echinococcus granulosus LRP2 binding protein 0.0023 0.001 0.0015
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0017 0.0154
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0032
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.003 0.0095
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0055 0.0052 0.8133
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus multilocularis Niemann Pick C1 protein 0.0162 0.0195 0.0195
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0005 0.0005
Onchocerca volvulus 0.0029 0.0019 0.0059
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0017 0.0055
Echinococcus granulosus Niemann Pick C1 protein 0.0162 0.0195 0.031
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0005 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.001 0.0032
Echinococcus multilocularis importin subunit beta 1 0.0054 0.0052 0.0051
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0021 0.0007 0.0012
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0025 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Leishmania major pyruvate kinase 0.0029 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0096
Plasmodium vivax vivapain-1 0.0017 0.0002 0.0037
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0044 0.0038 0.0061
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0034 0.0627
Brugia malayi Matrixin family protein 0.0085 0.0093 0.0299
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0024 0.0078
Entamoeba histolytica hypothetical protein 0.0197 0.0241 0.4738
Echinococcus multilocularis thymidylate synthase 0.007 0.0073 0.0072
Trypanosoma cruzi Sel1 repeat, putative 0.0023 0.001 0.0031
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0025 0.0039
Trypanosoma cruzi importin beta-1 subunit, putative 0.0044 0.0038 0.0122
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Brugia malayi AMP-binding enzyme family protein 0.003 0.0019 0.0061
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0017 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0017 0.0107
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0017 0.0002 0.0012
Mycobacterium leprae Probable pyruvate kinase PykA 0.0029 0.0018 0.0747
Echinococcus granulosus hypothetical protein 0.0033 0.0024 0.0038
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0045 0.0039 0.0739
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0043 0.0036 0.0117
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0024 0.0038
Trypanosoma brucei pyruvate kinase 1, putative 0.0029 0.0018 0.0058
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0025 0.0024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0024 0.0038
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0045 0.0039 0.0127
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0071 0.1357
Entamoeba histolytica cysteine proteinase, putative 0.0021 0.0007 0.0104
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0045 0.0039 0.0127
Loa Loa (eye worm) hypothetical protein 0.0051 0.0048 0.0155
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0037 0.0029 0.0046
Toxoplasma gondii FATC domain-containing protein 0.0021 0.0007 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0148 0.0235
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Mycobacterium ulcerans hypothetical protein 0.005 0.0046 0.0429
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0009 0.0027
Brugia malayi hypothetical protein 0.0023 0.001 0.0031
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0045 0.0039 0.0039
Plasmodium vivax vivapain-3 0.0017 0.0002 0.0037
Trichomonas vaginalis penicillin-binding protein, putative 0.019 0.0232 0.2746
Loa Loa (eye worm) hypothetical protein 0.0065 0.0066 0.0212
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0029 0.0046
Trypanosoma cruzi polo-like protein kinase, putative 0.0061 0.006 0.0194
Brugia malayi Sodium:neurotransmitter symporter family protein 0.042 0.0537 0.1737
Loa Loa (eye worm) hypothetical protein 0.019 0.0232 0.0751
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0016
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0029 0.0019 0.0328
Brugia malayi MH2 domain containing protein 0.0051 0.0048 0.0154
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0029 0.0019 0.0061
Trichomonas vaginalis fk506-binding protein, putative 0.0055 0.0052 0.0598
Schistosoma mansoni SET domain protein 0.002 0.0007 0.0011
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0019 0.0004 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0057 0.0658
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Brugia malayi Aldehyde dehydrogenase protein 4 0.0045 0.0039 0.0127
Brugia malayi TAR-binding protein 0.0127 0.0148 0.0477
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0115 0.0182
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0094 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0011 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0012 0.0115
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.005 0.0046 0.0073
Schistosoma mansoni ap endonuclease 0.0043 0.0036 0.0058
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0016 0.0002 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trypanosoma brucei pyruvate kinase 1 0.0029 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Loa Loa (eye worm) glutaminase 0.0208 0.0256 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0045 0.0039 0.0063
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0091 0.0145
Toxoplasma gondii ABC1 family protein 0.019 0.0232 0.2183
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0019 0.0004 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.4755 0.6282 1
Onchocerca volvulus Matrilysin homolog 0.0085 0.0093 0.0304
Echinococcus granulosus fibrillin 2 0.0028 0.0017 0.0027
Brugia malayi jmjC domain containing protein 0.0058 0.0057 0.0182
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0513 0.066 0.2134
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0024 0.0038
Schistosoma mansoni lamin 0.0193 0.0236 0.0375
Brugia malayi ecdysteroid receptor 0.0034 0.0025 0.0079
Mycobacterium leprae PROBABLE HYDROLASE 0.0104 0.0117 0.504
Mycobacterium leprae Probable lipase LipE 0.019 0.0232 1
Mycobacterium ulcerans polyketide synthase Pks13 0.0024 0.0011 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Trichomonas vaginalis importin beta-1, putative 0.0044 0.0038 0.0429
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Onchocerca volvulus 0.0162 0.0195 0.0642
Trichomonas vaginalis CAMK family protein kinase 0.003 0.002 0.0215
Schistosoma mansoni hypothetical protein 0.0567 0.0731 0.1164
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0089 0.104
Trypanosoma brucei importin beta-1 subunit, putative 0.0054 0.0052 0.0166
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0033 0.0374
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0012 0.0227
Brugia malayi Cytochrome P450 family protein 0.0048 0.0043 0.0138
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0016 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0066 0.0068 0.0784
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0397 0.0506 0.9411
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0019 0.0004 0.0007
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0104 0.0117 0.0736
Schistosoma mansoni nuclear receptor 0.0016 0.0001 0.0002
Echinococcus granulosus FK506 binding protein 2 0.0055 0.0052 0.0083
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0045 0.0039 0.0363
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.024
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0046 0.0429
Brugia malayi Heterochromatin protein 1 0.0147 0.0175 0.0565
Schistosoma mansoni inositol monophosphatase 0.0062 0.0062 0.0099
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0017 0.0154
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0034 0.0025 0.0039
Schistosoma mansoni amine GPCR 0.0033 0.0024 0.0038
Onchocerca volvulus 0.0024 0.0012 0.0036
Brugia malayi hypothetical protein 0.0018 0.0004 0.0011
Entamoeba histolytica heat shock transcription factor, putative 0.0104 0.0118 0.2301
Giardia lamblia Tenascin-like 0.0028 0.0017 0.026
Schistosoma mansoni coup transcription factor 0.0034 0.0025 0.0039
Schistosoma mansoni hypothetical protein 0.1405 0.1842 0.2933
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0017 0.0154
Trypanosoma brucei Sel1 repeat, putative 0.0023 0.001 0.0031
Echinococcus granulosus lamin dm0 0.0193 0.0236 0.0375
Echinococcus granulosus orexin receptor type 2 0.0033 0.0024 0.0038
Plasmodium falciparum pyruvate kinase 0.0029 0.0018 0.0354
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0024 0.0078
Schistosoma mansoni biogenic amine receptor 0.0033 0.0024 0.0038
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0024 0.0077
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0089 0.0287
Brugia malayi Matrixin family protein 0.0085 0.0093 0.0299
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0016 0.0002 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0102 0.0115 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.019 0.0232 0.075
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0024 0.0024
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0016 0.0001 0.0004
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.0029 0.0029
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0045 0.0039 0.0246
Trichomonas vaginalis penicillin-binding protein, putative 0.019 0.0232 0.2746
Trypanosoma cruzi pyruvate kinase 2, putative 0.0029 0.0018 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0085 0.0093 0.0148
Echinococcus multilocularis dnaJ subfamily B 0.2784 0.3669 0.3669
Echinococcus multilocularis chromobox protein 1 0.0147 0.0175 0.0175
Schistosoma mansoni hypothetical protein 0.0197 0.0241 0.0383
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0148 0.0235
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0093 0.0103 0.0164
Trypanosoma cruzi cysteine peptidase, putative 0.0102 0.0115 0.037
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0017
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0124 0.0144 0.0466
Echinococcus multilocularis musashi 0.0193 0.0236 0.0235
Schistosoma mansoni GTP-binding protein alpha subunit 0.0019 0.0005 0.0008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0193 0.0236 0.0763
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0012 0.0074
Schistosoma mansoni aldehyde dehydrogenase 0.0045 0.0039 0.0063
Schistosoma mansoni hypothetical protein 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0096
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0024 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.019 0.0232 0.1457
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0025 0.0039
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0036 0.0409
Onchocerca volvulus 0.0055 0.0052 0.017
Schistosoma mansoni dihydrofolate reductase 0.0029 0.0018 0.0028
Echinococcus multilocularis Niemann Pick C1 protein 0.0114 0.013 0.013
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0017 0.016
Mycobacterium ulcerans polyketide synthase 0.0017 0.0002 0.0012
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0029 0.0018 0.0158
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.0029 0.0046
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0045 0.0039 0.0363
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0024 0.0078
Onchocerca volvulus 0.0033 0.0024 0.0077
Brugia malayi Glycosyl hydrolases family 31 protein 0.0183 0.0223 0.072
Brugia malayi EGF-like domain containing protein 0.0028 0.0017 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0007 0.0063
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0071 0.0074 0.0118
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0024 0.0078
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0106 0.0666
Echinococcus granulosus smad 0.0115 0.0132 0.021
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0034 0.0108
Brugia malayi MH1 domain containing protein 0.0064 0.0064 0.0207
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0001 0.0001
Giardia lamblia Alcohol dehydrogenase 0.0045 0.0039 0.0698
Loa Loa (eye worm) intermediate filament protein 0.0193 0.0236 0.0763
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0039 0.044
Trypanosoma cruzi hypothetical protein, conserved 0.019 0.0232 0.075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0262 0.0328 0.0522
Treponema pallidum sodium- and chloride- dependent transporter 0.042 0.0537 1
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0045 0.0039 0.0127
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0025 0.0024
Echinococcus granulosus pyruvate kinase 0.0029 0.0018 0.0028
Schistosoma mansoni protein kinase 0.0156 0.0187 0.0297
Mycobacterium ulcerans glutaminase 0.0208 0.0256 0.2405
Schistosoma mansoni opsin-like receptor 0.0033 0.0024 0.0038
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0045 0.0039 0.0246
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0029 0.0019 0.0364
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0068 0.007 0.0816
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0012 0.0018
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0051 0.0048 0.0153
Loa Loa (eye worm) norepinephrine transporter 0.042 0.0537 0.1737
Schistosoma mansoni importin beta-1 0.0054 0.0052 0.0082
Plasmodium falciparum amino acid transporter, putative 0.0071 0.0074 0.1466
Brugia malayi hypothetical protein 0.0018 0.0004 0.0011
Trichomonas vaginalis hypothetical protein 0.0023 0.001 0.0091
Echinococcus multilocularis cathepsin L cysteine protease 0.0029 0.0019 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0024 0.0011 0.0106
Leishmania major related to elongation factor-2 kinase efk-1b isoform-like protein 0.0182 0.0221 0.0713
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0446 0.057 0.0907
Toxoplasma gondii histone lysine methyltransferase SET1 0.0376 0.0478 0.4495
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0055 0.0052 0.0798
Onchocerca volvulus 0.0033 0.0024 0.0077
Schistosoma mansoni sodium/chloride dependent transporter 0.042 0.0537 0.0855
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.004 0.0033 0.0642
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0016 0.0002 0.0006
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0019 0.0004 0.0007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0397 0.0506 0.1636
Echinococcus granulosus cathepsin l1 0.0021 0.0007 0.0011
Onchocerca volvulus 0.0033 0.0024 0.0077
Onchocerca volvulus 0.0033 0.0024 0.0077
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0019 0.0004 0.0004
Brugia malayi Dopamine receptor protein 2 0.0033 0.0024 0.0077
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0005 0.0015
Schistosoma mansoni kinase 0.0031 0.0021 0.0034
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Plasmodium falciparum plasmepsin I 0.0021 0.0007 0.0139
Echinococcus granulosus tumor protein p63 0.1107 0.1447 0.2304
Brugia malayi Serine protease Z688.6 precursor 0.0019 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0012
Mycobacterium leprae Probable polyketide synthase Pks1 0.0017 0.0002 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.006 0.0096
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0036 0.0409
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.0102 0.0115 0.0182
Schistosoma mansoni vesicular acetylcholine transporter 0.2291 0.3016 0.4801
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0089 0.0098 0.0155
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0019 0.0005 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Trypanosoma cruzi cysteine protease, putative 0.0017 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0099 0.0111 0.2181
Brugia malayi ecdysone receptor 0.0016 0.0001 0.0002
Schistosoma mansoni tyrosine kinase 0.0249 0.0309 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0053 0.005 0.0161
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0134 0.0157 0.0508
Echinococcus multilocularis chromobox protein 1 0.0147 0.0175 0.0175
Schistosoma mansoni sodium/chloride dependent transporter 0.0071 0.0074 0.0118
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0033 0.0053
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.019 0.0232 0.0751
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0033 0.0033
Echinococcus multilocularis protein jagged 2 0.0028 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0102 0.0115 0.0371
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0046 0.0149
Echinococcus multilocularis Peptidase C54 0.0066 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0017
Mycobacterium tuberculosis Probable lipase LipD 0.019 0.0232 0.1457
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Loa Loa (eye worm) mbt repeat family protein 0.0045 0.0039 0.0128
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Onchocerca volvulus Cathepsin F homolog 0.0029 0.0019 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Leishmania major aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Plasmodium vivax ubiquitin-protein ligase, putative 0.0023 0.001 0.0188
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.019 0.0232 0.0369
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0019 0.0005 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0024 0.0038
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0017 0.0154
Mycobacterium ulcerans thymidylate synthase 0.007 0.0073 0.0677
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0045 0.0039 0.0363
Schistosoma mansoni glutaminase 0.0208 0.0256 0.0408
Leishmania major cathepsin L-like protease 0.0029 0.0019 0.006
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Loa Loa (eye worm) hypothetical protein 0.0623 0.0805 0.2606
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0446 0.057 0.0908
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0017 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0033 0.0374
Loa Loa (eye worm) hypothetical protein 0.0342 0.0433 0.1403
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0446 0.057 0.1846
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0045 0.0039 0.0246
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0019 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0134 0.0157 0.0508
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Loa Loa (eye worm) Smad1 0.0115 0.0132 0.0428
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0025 0.0039
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0024 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0058
Brugia malayi AMP-binding enzyme family protein 0.005 0.0046 0.0149
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0024 0.0038
Echinococcus granulosus dna polymerase kappa 0.0019 0.0005 0.0007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.019 0.0232 0.0369
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0017 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Onchocerca volvulus 0.0055 0.0052 0.017
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0025 0.0039
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0012 0.0105
Onchocerca volvulus Phospholipase A2 homolog 0.0492 0.0632 0.2091
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0066 0.0068 0.0784
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.0148 0.0478
Brugia malayi dihydrofolate reductase family protein 0.0029 0.0018 0.0056
Mycobacterium tuberculosis Conserved protein 0.019 0.0232 0.1457
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0001 0.0002
Schistosoma mansoni cpg binding protein 0.0195 0.0239 0.038
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0045 0.0039 0.0368
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0091 0.0295
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0099 0.0111 0.0357
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0091 0.0295
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0045 0.0039 0.0363
Entamoeba histolytica hypothetical protein, conserved 0.0182 0.0221 0.4338
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.042 0.0537 0.1737
Brugia malayi hypothetical protein 0.0053 0.005 0.0162
Brugia malayi Hemopexin family protein 0.0121 0.014 0.0452
Schistosoma mansoni neuropeptide receptor 0.0033 0.0024 0.0038
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0078 0.0084 0.0132
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0055 0.0052 0.0169
Loa Loa (eye worm) hypothetical protein 0.0085 0.0093 0.03
Mycobacterium tuberculosis Conserved hypothetical protein 0.027 0.0338 0.2122
Echinococcus multilocularis cathepsin b 0.0124 0.0144 0.0144
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0005 0.0036
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0019 0.0005 0.0008
Onchocerca volvulus 0.0193 0.0236 0.0778
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0012 0.0108
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0025 0.0024
Echinococcus granulosus TGF beta signal transducer SmadC 0.0115 0.0132 0.021
Schistosoma mansoni chromobox protein 0.0024 0.0012 0.0019
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.019 0.0232 0.0751
Toxoplasma gondii aspartyl protease ASP1 0.0021 0.0007 0.0066
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0045 0.0039 0.0062
Trypanosoma brucei hypothetical protein, conserved 0.019 0.0232 0.075
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0043 0.0139
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0002 0.0003
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0019 0.0004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0018
Schistosoma mansoni ets-related 0.016 0.0192 0.0306
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0165 0.7104
Schistosoma mansoni Smad4 0.0051 0.0048 0.0076
Schistosoma mansoni smad1 5 8 and 0.0115 0.0132 0.0211
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0012 0.0011
Brugia malayi Pre-SET motif family protein 0.0085 0.0093 0.03
Schistosoma mansoni myelin transcription factor 1 myt1 0.0051 0.0048 0.0076
Brugia malayi Cytochrome P450 family protein 0.0048 0.0043 0.0138
Echinococcus multilocularis Chromo domain 0.0024 0.0012 0.0011
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0036 0.0715
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0024 0.0024
Echinococcus multilocularis serotonin transporter 0.042 0.0537 0.0537
Giardia lamblia Tenascin-37 0.0028 0.0017 0.026
Brugia malayi beta-lactamase family protein 0.019 0.0232 0.075
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0024 0.0024
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0019 0.0005 0.0016
Echinococcus granulosus Niemann Pick C1 protein 0.0114 0.013 0.0207
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0156 0.0187 0.0297
Trypanosoma cruzi polo-like protein kinase, putative 0.0061 0.006 0.0194
Loa Loa (eye worm) matrix metalloproteinase 0.0085 0.0093 0.03
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0044 0.007
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0024 0.0038
Entamoeba histolytica elongation factor-2 kinase, putative 0.0182 0.0221 0.4338
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.2291 0.3016 0.976
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0114 0.013 0.2546
Brugia malayi tailless protein 0.0016 0.0001 0.0002
Onchocerca volvulus 0.0029 0.0019 0.0059
Echinococcus multilocularis pyruvate kinase 0.0029 0.0018 0.0018
Brugia malayi Matrixin family protein 0.0206 0.0253 0.0818
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Echinococcus multilocularis neuropeptide receptor A26 0.1017 0.1327 0.1327
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0156
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.0698
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0059 0.0058 0.0189
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0024 0.0038
Brugia malayi PHD-finger family protein 0.0035 0.0026 0.0083
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0397 0.0506 1
Loa Loa (eye worm) matrixin family protein 0.0189 0.023 0.0746
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Echinococcus multilocularis protein patched 0.0049 0.0044 0.0044
Loa Loa (eye worm) cathepsin B 0.0044 0.0038 0.0124
Brugia malayi Matrixin family protein 0.0085 0.0093 0.0299
Schistosoma mansoni intermediate filament proteins 0.0193 0.0236 0.0375
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0019 0.0005 0.0017
Echinococcus multilocularis cathepsin L cysteine protease 0.0029 0.0019 0.0018
Schistosoma mansoni hypothetical protein 0.1405 0.1842 0.2933
Onchocerca volvulus Matrix metalloproteinase homolog 0.0189 0.023 0.0761
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0074 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0012 0.0115
Echinococcus granulosus histone acetyltransferase MYST2 0.0051 0.0048 0.0075
Echinococcus multilocularis muscleblind protein 0.0459 0.0588 0.0588
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0025 0.0079
Loa Loa (eye worm) inositol-1 0.0062 0.0062 0.02
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0089 0.0098 0.0155
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0817 0.1062 0.169
Echinococcus granulosus protein sel 1 1 0.0023 0.001 0.0015
Schistosoma mansoni lamin 0.0193 0.0236 0.0375
Giardia lamblia Hypothetical protein 0.0055 0.0052 0.0954
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0012
Toxoplasma gondii Sel1 repeat-containing protein 0.0023 0.001 0.0089
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.007 0.0073 0.0455
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0033 0.0621
Brugia malayi RE15519p 0.0033 0.0024 0.0077
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0017 0.0027
Mycobacterium tuberculosis Probable hydrolase 0.019 0.0232 0.1457
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.0067
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.024
Brugia malayi beta-lactamase 0.019 0.0232 0.075
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Onchocerca volvulus 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0082 0.0089 0.0288
Echinococcus granulosus cathepsin l cysteine peptidase 0.0029 0.0019 0.0029
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0024 0.0024
Echinococcus granulosus Smad4 0.0115 0.0132 0.021
Loa Loa (eye worm) hypothetical protein 0.0506 0.0651 0.2106
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Loa Loa (eye worm) ctsf protein 0.0029 0.0019 0.0061
Brugia malayi RNA binding protein 0.0127 0.0148 0.0477
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0053 0.005 0.005
Schistosoma mansoni neuropeptide receptor 0.0033 0.0024 0.0038
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0055 0.0052 0.0489
Echinococcus granulosus cysteine protease 0.0017 0.0002 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0085 0.0093 0.0874
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0158 0.0189 0.0624
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.007 0.0073 0.0116
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.0067
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0001 0.0003
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0105
Onchocerca volvulus 0.0195 0.0239 0.0789
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0071 0.0074 1
Plasmodium falciparum plasmepsin VI 0.0021 0.0007 0.0139
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0104 0.0117 0.0379
Giardia lamblia Cathepsin B precursor 0.0044 0.0038 0.0678
Schistosoma mansoni hypothetical protein 0.0024 0.0012 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0017 0.0154
Toxoplasma gondii pyruvate kinase PyK1 0.0029 0.0018 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0025 0.0024
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Schistosoma mansoni amine GPCR 0.0033 0.0024 0.0038
Echinococcus multilocularis chromobox protein 2 0.0024 0.0012 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0197 0.0241 0.0383
Echinococcus multilocularis mothers against decapentaplegic 5 0.0115 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0024
Echinococcus multilocularis eukaryotic elongation factor 2 kinase 0.0623 0.0805 0.0805
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0005 0.0034
Schistosoma mansoni smad 0.0051 0.0048 0.0076
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0005 0.0016
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0001 0.0001
Plasmodium vivax plasmepsin IV, putative 0.0021 0.0007 0.0139
Brugia malayi conserved hypotetical protein 0.0016 0.0001 0.0002
Echinococcus multilocularis sex peptide receptor 0.0033 0.0024 0.0024
Schistosoma mansoni amine GPCR 0.0033 0.0024 0.0038
Onchocerca volvulus 0.0029 0.0019 0.0059
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0262 0.0328 0.0327
Onchocerca volvulus Phospholipase A2 homolog 0.0104 0.0117 0.0385
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0397 0.0506 0.1636
Echinococcus granulosus neutral alpha glucosidase AB 0.0041 0.0034 0.0053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.042 0.0537 0.0855
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0024 0.0024
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0025 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0019 0.0005 0.0008
Echinococcus granulosus snurportin 1 0.0579 0.0747 0.1189
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0024 0.0011 0.0106
Brugia malayi cathepsin L-like precursor 0.0021 0.0007 0.0023
Giardia lamblia hypothetical protein 0.0028 0.0017 0.026
Schistosoma mansoni sodium/chloride dependent transporter 0.0072 0.0076 0.012
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0032 0.0023 0.0036
Loa Loa (eye worm) RNA binding protein 0.0127 0.0148 0.0478
Schistosoma mansoni sodium-dependent amino acid transporter 0.0071 0.0074 0.0118
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0045 0.0039 0.0445
Entamoeba histolytica hypothetical protein 0.0197 0.0241 0.4738
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.003 0.002 0.0063
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Loa Loa (eye worm) hypothetical protein 0.0162 0.0195 0.063
Entamoeba histolytica hypothetical protein, conserved 0.0182 0.0221 0.4338
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0128 0.0149 0.0482
Schistosoma mansoni Smad4 0.0115 0.0132 0.0211
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0017 0.0002 0.0057
Toxoplasma gondii isocitrate dehydrogenase 0.0022 0.0009 0.0078
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0017 0.0154
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0262 0.0328 0.0327
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0024 0.0024
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0055 0.0053 0.0333
Echinococcus granulosus mothers against decapentaplegic 6 0.0051 0.0048 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0024
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0243 0.0302 0.0975
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0096
Trypanosoma cruzi myosin heavy chain kinase A, putative 0.0623 0.0805 0.2606
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0024 0.0038
Brugia malayi prolyl oligopeptidase family protein 0.0158 0.0189 0.0611
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0446 0.057 0.0908
Onchocerca volvulus 0.0033 0.0024 0.0077
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Brugia malayi hypothetical protein 0.0016 0.0001 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0024 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0045 0.0039 0.0063
Mycobacterium tuberculosis Probable reductase 0.0086 0.0094 0.0586
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0055 0.0052 0.0169
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0017 0.0107
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0096
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0017 0.0002 0.0012
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Echinococcus multilocularis GTP binding nuclear protein Ran 0.004 0.0033 0.0032
Echinococcus granulosus Dipeptidyl peptidase 9 0.0053 0.005 0.0079
Loa Loa (eye worm) TAR-binding protein 0.0127 0.0148 0.0478
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0024 0.0024
Echinococcus granulosus cathepsin L cysteine protease 0.0017 0.0002 0.0003
Echinococcus multilocularis pyruvate kinase 0.0023 0.001 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0025 0.0039
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0052 0.0048 0.0048
Mycobacterium leprae Polyketide synthase Pks13 0.0024 0.0011 0.045
Brugia malayi sel-1 0.0023 0.001 0.0031
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0049 0.0921
Brugia malayi Cathepsin L-like precursor 0.0021 0.0007 0.0023
Brugia malayi hypothetical protein 0.0626 0.081 0.2619
Mycobacterium tuberculosis Hypothetical protein 0.0033 0.0024 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0039 0.0434
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0025 0.0079
Onchocerca volvulus 0.0029 0.0019 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0025 0.0024
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0397 0.0506 0.1636
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0089 0.1752
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Brugia malayi EGF-like domain containing protein 0.0028 0.0017 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0024 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Schistosoma mansoni immunophilin 0.0342 0.0433 0.069
Leishmania major mitochondrial DNA polymerase beta 0.0513 0.066 0.2134
Giardia lamblia Kinase, PLK 0.0061 0.006 0.1116
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0057 0.009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0045 0.0039 0.0368
Trichomonas vaginalis hypothetical protein 0.0023 0.001 0.0091
Entamoeba histolytica hypothetical protein 0.0024 0.0011 0.0176
Entamoeba histolytica peptidase, C54 family 0.0026 0.0014 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0004 0.0026
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0029 0.0018 0.0113
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0029 0.0019 0.0364
Schistosoma mansoni nuclear receptor 0.0016 0.0001 0.0002
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0062 0.0062 0.1186
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0019 0.006
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0397 0.0506 0.6016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0059 0.0058 0.0093
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0019 0.003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0024 0.0038
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0072 0.0075 0.0243
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0359 0.7075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0062 0.0199
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0066 0.0068 0.0108
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0026 0.0014 0.0045
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Brugia malayi vesicular acetylcholine transporter unc-17 0.2291 0.3016 0.976
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Brugia malayi nuclear receptor NHR-88 0.0016 0.0001 0.0002
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0045 0.0039 0.0127
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0017 0.0154
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0039
Treponema pallidum gamma-glutamyl phosphate reductase 0.0045 0.0039 0.0554
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Onchocerca volvulus 0.0106 0.012 0.0396
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0066 0.0068 0.0218
Onchocerca volvulus 0.0065 0.0066 0.0214
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0045 0.0039 0.0127
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0045 0.0039 0.0128
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0012 0.0227
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0029 0.0019 0.0198
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0017 0.0154
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0463 0.0593 0.0593
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0106 0.0666
Leishmania major pyruvate kinase 0.0029 0.0018 0.0058
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0025 0.0039
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0071 0.0074 0.0118
Brugia malayi Isocitrate dehydrogenase 0.0022 0.0009 0.0027
Schistosoma mansoni elongation factor 2 kinase 0.0182 0.0221 0.0351
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0091 0.1066
Echinococcus granulosus fmrfamide receptor 0.0033 0.0024 0.0038
Onchocerca volvulus Serine\/threonine kinase homolog 0.0061 0.006 0.0197
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0019 0.0005 0.0008
Echinococcus granulosus mothers against decapentaplegic 2 0.0051 0.0048 0.0076
Plasmodium falciparum glutathione reductase 0.0038 0.003 0.0582
Onchocerca volvulus Huntingtin homolog 0.0506 0.0651 0.2155
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0046 0.0149
Entamoeba histolytica Ran family GTPase 0.004 0.0033 0.0607
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0024 0.0011 0.0069
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0034 0.0377
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0089 0.1719
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.083 0.1079 0.3492
Onchocerca volvulus 0.003 0.0019 0.006
Schistosoma mansoni cpg binding protein 0.0208 0.0256 0.0408
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0344 0.0436 0.0436
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0397 0.0506 1
Brugia malayi ERG2 and Sigma1 receptor like protein 0.2347 0.309 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0025 0.008
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0046 0.0149
Echinococcus multilocularis expressed conserved protein 0.0107 0.0121 0.0121
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0397 0.0506 0.1636
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0025 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Echinococcus multilocularis fibrillin 2 0.0028 0.0017 0.0017
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0045 0.0039 0.0368
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Schistosoma mansoni autophagin-1 (C54 family) 0.0066 0.0068 0.0108
Echinococcus granulosus cathepsin L 0.0017 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0044 0.0505
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0009 0.0027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0025 0.0039
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0024 0.0038
Schistosoma mansoni sex comb on midleg homolog 0.0045 0.0039 0.0063
Brugia malayi G-protein coupled receptor 0.0033 0.0024 0.0077
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0019 0.003
Brugia malayi hypothetical protein 0.0019 0.0005 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.0015
Brugia malayi GnHR receptor homolog 0.0033 0.0024 0.0077
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0091 0.0295
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0045 0.0039 0.0039
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0025 0.0039
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0066 0.0068 0.0784
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0262 0.0327 0.1059
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0045 0.0039 0.0363
Mycobacterium leprae conserved hypothetical protein 0.019 0.0232 1
Schistosoma mansoni hypothetical protein 0.0262 0.0328 0.0522
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0019 0.0005 0.0005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.019 0.0232 0.0751
Leishmania major hypothetical protein, conserved 0.0211 0.026 0.0839
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0059 0.0058 0.0093
Echinococcus multilocularis lamin 0.0193 0.0236 0.0235
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0072 0.0075 0.0243
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0024 0.0024
Onchocerca volvulus 0.0021 0.0007 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0025 0.008
Giardia lamblia High cysteine protein 0.0028 0.0017 0.026
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0045 0.0039 0.0127
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0055 0.0052 0.0489
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0004 0.0011
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0045 0.0039 0.0127
Trichomonas vaginalis hypothetical protein 0.0024 0.0012 0.0115
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0055 0.0052 0.6547
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.0148 0.0477
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0005 0.003
Trichomonas vaginalis hypothetical protein 0.0024 0.0011 0.011
Toxoplasma gondii hypothetical protein 0.0071 0.0074 0.0698
Leishmania major cysteine peptidase A (CPA) 0.0029 0.0019 0.006
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0024 0.0024
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0094 0.0586
Onchocerca volvulus 0.0649 0.0839 0.2781
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0019 0.0004 0.0026
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0045 0.0039 0.0246
Schistosoma mansoni inositol monophosphatase 0.0062 0.0062 0.0099
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Schistosoma mansoni neuropeptide receptor 0.0033 0.0024 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0025 0.0079
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0043 0.0036 0.0639
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2347 0.309 1
Echinococcus multilocularis cysteine protease 0.0029 0.0019 0.0018
Echinococcus granulosus neuropeptide receptor A26 0.1017 0.1327 0.2112
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0002 0.0006
Loa Loa (eye worm) TK/FAK protein kinase 0.0251 0.0313 0.1013
Loa Loa (eye worm) cysteine protease 0.0029 0.0019 0.0061
Plasmodium falciparum plasmepsin II 0.0021 0.0007 0.0139
Giardia lamblia Pyruvate kinase 0.0029 0.0018 0.0275
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0045 0.0039 0.0127
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0397 0.0506 0.1636
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0043 0.0139
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0091 0.1066
Loa Loa (eye worm) heterochromatin protein 1 0.0147 0.0175 0.0566
Echinococcus multilocularis mothers against decapentaplegic 2 0.0051 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Brugia malayi cytochrome P450 0.0028 0.0017 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0024 0.0038
Onchocerca volvulus 0.0071 0.0074 0.0243
Loa Loa (eye worm) hypothetical protein 0.0114 0.013 0.0422
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0045 0.0039 0.0363
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0012 0.0191
Plasmodium vivax ubiquitin-protein ligase, putative 0.0023 0.001 0.0188
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0007 0.0139
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0053 0.005 0.0162
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0019 0.0328
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Mycobacterium tuberculosis Probable lipase LipE 0.019 0.0232 0.1457
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0012 0.0115
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0128
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0016 0.0002 0.0008
Trypanosoma cruzi Sel1 repeat, putative 0.0023 0.001 0.0031
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0017 0.0154
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0002 0.0006
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.001 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0017 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0024 0.0011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.007 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Onchocerca volvulus 0.0033 0.0024 0.0077
Schistosoma mansoni hypothetical protein 0.0262 0.0328 0.0522
Loa Loa (eye worm) CXXC zinc finger family protein 0.0195 0.0239 0.0773
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0055 0.0052 0.0954
Schistosoma mansoni cathepsin F (C01 family) 0.0021 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0019 0.0005 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0056
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0463 0.0593 0.0944
Echinococcus multilocularis serotonin receptor 0.0033 0.0024 0.0024
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0033 0.0053
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0025 0.0013 0.0124
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0071 0.0074 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0397 0.0506 0.0805
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0043 0.0036 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0091 0.0296
Schistosoma mansoni cathepsin D (A01 family) 0.0061 0.0061 0.0097
Echinococcus granulosus fibrillin 1 0.0028 0.0017 0.0027
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0071 0.0227
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0165 0.1036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0015
Echinococcus granulosus neuropeptide receptor 0.0033 0.0024 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0011 0.0106
Schistosoma mansoni neuropeptide receptor 0.0033 0.0024 0.0038
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0098 0.032
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Echinococcus multilocularis SAM and MBT domain containing protein 0.0045 0.0039 0.0039
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0055 0.0052 0.0169
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0062 0.0062 0.058
Schistosoma mansoni eukaryotic elongation factor 2 kinase (eef-2 kinase) 0.0623 0.0805 0.1282
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0016 0.0002 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0045 0.0039 0.1665
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0025 0.0079
Trypanosoma brucei hypothetical protein, conserved 0.0055 0.0052 0.0168
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0025 0.0039
Brugia malayi Serotonin receptor 0.0033 0.0024 0.0077
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0817 0.1062 0.1062
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0053 0.005 0.0162
Schistosoma mansoni sex comb on midleg homolog 0.0045 0.0039 0.0063
Echinococcus multilocularis cysteine protease 0.0029 0.0019 0.0018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0062 0.0062 0.0713
Schistosoma mansoni fk506 binding protein 0.0055 0.0052 0.0083
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0019 0.0005 0.0008
Onchocerca volvulus 0.0085 0.0093 0.0304
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0021 0.0007 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0044 0.0038 0.0429
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0024 0.0077
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0045 0.0039 0.0368
Echinococcus multilocularis polycomb protein SCMH1 0.0045 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0045 0.004 0.0129
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0041 0.0034 0.0109
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0463 0.0593 0.1918
Loa Loa (eye worm) thymidylate synthase 0.007 0.0073 0.0235
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0034 0.0377
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0089 0.0098 0.0155
Echinococcus multilocularis cathepsin b 0.0124 0.0144 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Trichomonas vaginalis fk506 binding protein, putative 0.0055 0.0052 0.0598
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0025 0.0079
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0012 0.0227
Chlamydia trachomatis pyruvate kinase 0.0029 0.0018 0.1244
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0019 0.0005 0.0005
Plasmodium falciparum zinc finger protein, putative 0.0025 0.0013 0.0248
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0005 0.0036
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0033 0.0107
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus multilocularis GPCR, family 2 0.0262 0.0328 0.0327
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.2291 0.3016 1
Brugia malayi Serine carboxypeptidase S28 family protein 0.0019 0.0004 0.0013
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0066 0.0068 0.0784
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0022 0.0009 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Brugia malayi nuclear receptor RXR 0.0016 0.0001 0.0002
Echinococcus multilocularis dna polymerase eta 0.0019 0.0005 0.0005
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0099 0.0111 0.0357
Brugia malayi Cathepsin L-like precursor 0.0029 0.0019 0.006
Trichomonas vaginalis pyruvate kinase, putative 0.0029 0.0018 0.0191
Brugia malayi Thioredoxin reductase 0.0038 0.003 0.0095
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0074 0.1466
Schistosoma mansoni hypothetical protein 0.0028 0.0017 0.0027
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0262 0.0328 0.0521
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0045 0.0039 0.0039
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.003 0.302
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0007 0.0023
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0024 0.0024
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0012 0.0115
Loa Loa (eye worm) hypothetical protein 0.019 0.0231 0.0748
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0025 0.008
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0091 0.0859
Schistosoma mansoni pyruvate kinase 0.0029 0.0018 0.0029
Trypanosoma brucei trypanothione reductase 0.0038 0.003 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Echinococcus multilocularis integrin beta 2 0.0652 0.0844 0.0843
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0025 0.0039
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0012 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0025 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Echinococcus granulosus vesicular acetylcholine transporter 0.2291 0.3016 0.4801
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0098 0.1139
Echinococcus granulosus GPCR family 2 0.0262 0.0328 0.0521
Giardia lamblia Cathepsin B precursor 0.0044 0.0038 0.0678
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0019 0.0004 0.0044
Trypanosoma cruzi cruzipain precursor, putative 0.0102 0.0115 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0093 0.0103 0.0333
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0004 0.0006
Treponema pallidum exodeoxyribonuclease (exoA) 0.0043 0.0036 0.0498
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0033 0.0053
Echinococcus granulosus polycomb protein SCMH1 0.0045 0.0039 0.0062
Loa Loa (eye worm) voltage-gated potassium channel 0.0449 0.0574 0.1858
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0091 0.0295
Loa Loa (eye worm) isocitrate dehydrogenase 0.0022 0.0009 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Brugia malayi Kelch motif family protein 0.0134 0.0157 0.0507
Giardia lamblia Neurogenic locus Notch protein precursor 0.0028 0.0017 0.026
Leishmania major cathepsin L-like protease 0.0029 0.0019 0.006
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0012 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0817 0.1062 0.1691
Plasmodium vivax SET domain protein, putative 0.0085 0.0093 0.1836
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Loa Loa (eye worm) hypothetical protein 0.0085 0.0093 0.03
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0397 0.0506 0.1636
Loa Loa (eye worm) hypothetical protein 0.0049 0.0044 0.0144
Echinococcus granulosus microtubule associated protein 2 0.4755 0.6282 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0025 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0027 0.0167
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0018 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0024 0.0038
Brugia malayi Bromodomain containing protein 0.0036 0.0028 0.0089
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0012 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0068 0.007 0.0816
Echinococcus granulosus serotonin transporter 0.042 0.0537 0.0854
Schistosoma mansoni hypothetical protein 0.0282 0.0353 0.0562
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0025 0.0024
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0055 0.0052 0.222
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0115 0.0132 0.0132
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0045 0.0039 0.0127
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0094 0.4007
Echinococcus granulosus adam 0.0028 0.0017 0.0027
Trypanosoma cruzi ISWI complex protein 0.0021 0.0007 0.0022
Echinococcus granulosus Chromo domain 0.0024 0.0012 0.0018
Giardia lamblia Tenascin-X 0.0028 0.0017 0.026
Toxoplasma gondii Sel1 repeat-containing protein 0.0023 0.001 0.0089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0009 0.0008
Brugia malayi neuropeptide F receptor 0.0033 0.0024 0.0077
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.0067
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0012 0.0227
Chlamydia trachomatis dihydrofolate reductase 0.0029 0.0018 0.1169
Leishmania major hypothetical protein, conserved 0.0023 0.001 0.0031
Echinococcus multilocularis lamin dm0 0.0193 0.0236 0.0235
Brugia malayi latrophilin 2 splice variant baaae 0.0567 0.0731 0.2366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Trichomonas vaginalis hypothetical protein 0.0028 0.0017 0.0182
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0132 0.0428
Echinococcus granulosus cathepsin b 0.0124 0.0144 0.0229
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0055 0.0052 0.0489
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0053 0.005 0.0162
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.003 0.058
Onchocerca volvulus 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0081 0.0088 0.0284
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0061 0.006 0.0195
Echinococcus granulosus GA binding protein alpha chain 0.0053 0.005 0.0079
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0017 0.0002 0.0012
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0046 0.0429
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Entamoeba histolytica peptidase, C54 family 0.0066 0.0068 0.1303
Trichomonas vaginalis set domain proteins, putative 0.0649 0.0839 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0024 0.0038
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0397 0.0506 0.0506
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0071 0.0074 0.024
Toxoplasma gondii type I fatty acid synthase, putative 0.0019 0.0005 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0048 0.0077
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0025 0.0079
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0057 0.0056
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0024 0.0077
Schistosoma mansoni chromobox protein 0.0024 0.0012 0.0019
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0055 0.0052 0.8133
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0012 0.0191
Mycobacterium ulcerans hypothetical protein 0.0055 0.0052 0.0484
Plasmodium vivax vivapain-2 0.0029 0.0019 0.0364
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0019 0.0004 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0091 0.1066
Brugia malayi ORL1-like opioid receptor 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0066 0.0068 0.0219
Loa Loa (eye worm) hypothetical protein 0.0492 0.0632 0.2044
Brugia malayi beta-lactamase family protein 0.019 0.0232 0.075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0074 0.0117
Toxoplasma gondii hypothetical protein 0.0071 0.0074 0.0698
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0022 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0019 0.006
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0012 0.0019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0024 0.0024
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0019 0.0005 0.0016
Echinococcus granulosus mixed lineage leukemia protein mll 0.0052 0.0048 0.0076
Echinococcus granulosus SAM and MBT domain containing protein 0.0045 0.0039 0.0062
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0017 0.0002 0.0012
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Brugia malayi Importin beta-1 subunit 0.0054 0.0052 0.0166
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0046 0.029
Echinococcus granulosus dihydrofolate reductase 0.0029 0.0018 0.0028
Echinococcus multilocularis cpg binding protein 0.0208 0.0256 0.0256
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0091 0.1736
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0071 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Brugia malayi CXXC zinc finger family protein 0.0195 0.0239 0.0772
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0019 0.0005 0.0016
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0043 0.0036 0.0118
Loa Loa (eye worm) aldehyde dehydrogenase 0.0045 0.0039 0.0128
Loa Loa (eye worm) hypothetical protein 0.12 0.1569 0.5079
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0089 0.104
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0012 0.0115
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0019 0.0005 0.0016
Toxoplasma gondii LsmAD domain-containing protein 0.0082 0.0089 0.0834
Plasmodium vivax hypothetical protein, conserved 0.019 0.0232 0.4585
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0115 0.0182
Entamoeba histolytica hypothetical protein 0.0024 0.0012 0.0191
Entamoeba histolytica hypothetical protein 0.0182 0.0221 0.4338
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0018 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0158 0.0189 0.0301
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0053 0.005 0.008
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0001 0.0002
Onchocerca volvulus 0.019 0.0232 0.0766
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0066 0.0068 0.0218
Trypanosoma brucei myosin heavy chain kinase A, putative 0.0623 0.0805 0.2606
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.007 0.0069
Mycobacterium ulcerans esterase/lipase LipP 0.019 0.0232 0.2179
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.0067
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Schistosoma mansoni adenoreceptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0626 0.081 0.262
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0043 0.0036 0.0036
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0016 0.0001 0.0004
Loa Loa (eye worm) nuclear factor I 0.0064 0.0064 0.0208
Echinococcus multilocularis 0.0028 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0183 0.0223 0.0721
Loa Loa (eye worm) hypothetical protein 0.0067 0.0069 0.0222
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0028 0.0017 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Loa Loa (eye worm) matrixin family protein 0.0206 0.0253 0.0819
Echinococcus multilocularis lysosomal alpha glucosidase 0.0183 0.0223 0.0222
Schistosoma mansoni hypothetical protein 0.0033 0.0024 0.0038
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0186 0.0226 0.0226
Echinococcus granulosus lamin 0.0193 0.0236 0.0375
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0019 0.0062
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.0029 0.0094
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0099 0.0111 0.2181
Echinococcus granulosus intermediate filament protein 0.0193 0.0236 0.0375
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0024 0.0038
Schistosoma mansoni hypothetical protein 0.0167 0.0201 0.032
Brugia malayi Serine protease Z688.6 precursor 0.0019 0.0004 0.0013
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0024 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0025 0.008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0005 0.003
Schistosoma mansoni hypothetical protein 0.0262 0.0328 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0004 0.0026
Onchocerca volvulus 0.0042 0.0036 0.0116
Leishmania major DNA polymerase eta, putative 0.0019 0.0005 0.0015
Brugia malayi aldehyde dehydrogenase 0.0045 0.0039 0.0127
Schistosoma mansoni aldehyde dehydrogenase 0.0817 0.1062 0.1691
Mycobacterium ulcerans pyruvate kinase 0.0029 0.0018 0.0163
Plasmodium falciparum cysteine proteinase falcipain 3 0.0029 0.0019 0.0364
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0055 0.0052 0.0954
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0197 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus granulosus Chromobox protein 3 0.0024 0.0012 0.0018
Echinococcus multilocularis LRP2 binding protein 0.0023 0.001 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.0232 0.2746
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Loa Loa (eye worm) hypothetical protein 0.005 0.0046 0.015
Loa Loa (eye worm) fatty acid synthase 0.0016 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0017 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.007 0.0073 0.3105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0001 0.0001
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0055 0.0052 0.0169
Schistosoma mansoni ran 0.004 0.0033 0.0052
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0059 0.0058 0.0671
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0019 0.0005 0.0017
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0002 0.0006
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0045 0.0039 0.0063
Loa Loa (eye worm) hypothetical protein 0.0051 0.0048 0.0154
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0041 0.0034 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Loa Loa (eye worm) hypothetical protein 0.009 0.0099 0.0319
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0019 0.0005 0.0016
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0017 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0025 0.008
Trichomonas vaginalis fk506-binding protein, putative 0.0397 0.0506 0.6016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0001 0.0002
Echinococcus granulosus importin subunit beta 1 0.0054 0.0052 0.0082
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0055 0.0052 0.0954
Giardia lamblia High cysteine protein 0.0028 0.0017 0.026
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0034 0.0377
Brugia malayi Fli-1 protein 0.016 0.0192 0.0622
Echinococcus granulosus cysteine protease atg4b 0.0066 0.0068 0.0107
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0463 0.0593 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0115
Entamoeba histolytica serine/threonine protein kinase, putative 0.0061 0.006 0.1155
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0071 0.0112
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0019 0.0005 0.0036
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0045 0.0039 0.0063
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0024 0.0024
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0045 0.0039 0.0363
Loa Loa (eye worm) hypothetical protein 0.042 0.0537 0.1737
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0024 0.0011 0.0069
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0002 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0029 0.0019 0.0198
Schistosoma mansoni alpha-glucosidase 0.0158 0.0189 0.0301
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0359 0.6626
Onchocerca volvulus 0.0019 0.0004 0.0011
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0022 0.0009 0.0053
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0165 0.1548
Schistosoma mansoni opsin-like receptor 0.0033 0.0024 0.0038
Brugia malayi G-protein coupled receptor 0.0033 0.0024 0.0077
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.004 0.0033 0.0105
Echinococcus granulosus serine protein kinase ATM 0.0021 0.0007 0.0011
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0103 0.0117 0.0378
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0089 0.0098 0.0097
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trypanosoma brucei hypothetical protein, conserved 0.0211 0.026 0.0839
Echinococcus multilocularis geminin 0.1405 0.1842 0.1842
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Echinococcus multilocularis vesicular acetylcholine transporter 0.2291 0.3016 0.3016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0024 0.0038
Brugia malayi Cathepsin L-like precursor 0.0029 0.0019 0.006
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0005 0.0015
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.001 0.0188
Onchocerca volvulus 0.0033 0.0024 0.0077
Brugia malayi Latrophilin receptor protein 2 0.0262 0.0328 0.106
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0197 0.0241 0.0383
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0045 0.0039 0.0127
Echinococcus multilocularis mothers against decapentaplegic 6 0.0051 0.0048 0.0048
Brugia malayi cathepsin B-like cysteine proteinase 0.0124 0.0144 0.0466
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0045 0.0039 0.0363
Echinococcus multilocularis protein sel 1 1 0.0023 0.001 0.0009
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0053 0.005 0.0162
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.026 0.0839
Echinococcus multilocularis sodium and chloride dependent glycine 0.0071 0.0074 0.0074
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0044 0.007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0017 0.0107
Echinococcus multilocularis smad 0.0115 0.0132 0.0132
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0397 0.0506 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0027 0.0167
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0102 0.0115 0.0114
Schistosoma mansoni smad1 5 8 and 0.0115 0.0132 0.0211
Echinococcus multilocularis somatostatin receptor 0.0033 0.0024 0.0024
Brugia malayi Protein kinase domain containing protein 0.0251 0.0313 0.1012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0024 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Loa Loa (eye worm) hypothetical protein 0.019 0.0232 0.0751
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.0089 0.0293
Leishmania major cathepsin L-like protease 0.0029 0.0019 0.006
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0044 0.0038 0.0123
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0093 0.0103 0.0334
Entamoeba histolytica hypothetical protein 0.0025 0.0013 0.0211
Brugia malayi cytoplasmic intermediate filament protein 0.0103 0.0117 0.0377
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.003 0.0096
Loa Loa (eye worm) histone methyltransferase 0.0063 0.0064 0.0207
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0024 0.0038
Leishmania major C-8 sterol isomerase-like protein 0.2347 0.309 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0007 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0034 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0033 0.0374
Echinococcus granulosus protein tyrosine kinase 0.0249 0.0309 0.0492
Onchocerca volvulus 0.0045 0.0039 0.0127
Echinococcus multilocularis dihydrofolate reductase 0.0029 0.0018 0.0017
Entamoeba histolytica hypothetical protein 0.0197 0.0241 0.4738
Brugia malayi Pre-SET motif family protein 0.057 0.0736 0.238
Echinococcus granulosus beta LACTamase domain containing family member 0.019 0.0232 0.0369
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0045 0.0039 0.0246
Echinococcus granulosus g protein coupled receptor 0.0033 0.0024 0.0038
Trypanosoma brucei cytochrome P450, putative 0.0048 0.0043 0.0138
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0017 0.0107
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0001 0.0001
Brugia malayi Integrin beta pat-3 precursor 0.088 0.1146 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0024 0.0011 0.0106
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.0108
Entamoeba histolytica pyruvate kinase, putative 0.002 0.0007 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.019 0.0232 0.075
Onchocerca volvulus 0.0193 0.0236 0.0778
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0024 0.0024
Echinococcus granulosus eukaryotic elongation factor 2 kinase 0.0623 0.0805 0.1282
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Schistosoma mansoni smad1 5 8 and 0.0115 0.0132 0.0211
Onchocerca volvulus 0.0028 0.0017 0.0054
Entamoeba histolytica hypothetical protein 0.0024 0.0012 0.0191
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.031 0.0391 0.039
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0144 0.023
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0036 0.0715
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0071 0.0074 0.0074
Leishmania major cathepsin L-like protease 0.0102 0.0115 0.037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Loa Loa (eye worm) DR-78 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0091 0.0295
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0017 0.0107
Echinococcus multilocularis muscleblind protein 1 0.0459 0.0588 0.0588
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0045 0.0039 0.0739
Entamoeba histolytica heat shock transcription factor, putative 0.0104 0.0118 0.2301
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0025 0.008
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0024 0.0038
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0115 0.0132 0.0211
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.001 0.0088
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0045 0.0039 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0046 0.0429
Brugia malayi Cathepsin L-like cysteine proteinase 0.0021 0.0007 0.0023
Echinococcus granulosus lysosomal alpha glucosidase 0.0183 0.0223 0.0354
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.1028
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0397 0.0506 0.1636
Echinococcus granulosus expressed conserved protein 0.0107 0.0121 0.0193
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0144 0.023
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0019 0.0005 0.0008
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0033 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Brugia malayi Protein cec-1. 0.0024 0.0012 0.0037
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0025 0.0079
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0024 0.0038
Brugia malayi exodeoxyribonuclease III family protein 0.0043 0.0036 0.0117
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0024 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Loa Loa (eye worm) hypothetical protein 0.009 0.0099 0.0319
Brugia malayi hypothetical protein 0.0082 0.0089 0.0287
Loa Loa (eye worm) glutaminase 2 0.0208 0.0256 0.0829
Trypanosoma brucei unspecified product 0.0019 0.0005 0.0015
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0024 0.0077
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0024 0.0038
Onchocerca volvulus 0.0081 0.0088 0.0288
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Loa Loa (eye worm) beta-lactamase 0.019 0.0232 0.0751
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0148 0.0235
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Giardia lamblia Tenascin precursor 0.0028 0.0017 0.026
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0034 0.0377
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0196
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0046 0.0429
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0024 0.0078
Entamoeba histolytica hypothetical protein 0.0021 0.0007 0.0104
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0065 0.021
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0071 0.0074 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0018 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0025 0.0079
Mycobacterium ulcerans hypothetical protein 0.027 0.0338 0.3176
Brugia malayi hypothetical protein 0.0016 0.0001 0.0002
Toxoplasma gondii hypothetical protein 0.0028 0.0017 0.0161
Brugia malayi hypothetical protein 0.0134 0.0157 0.0507
Leishmania major cytochrome p450-like protein 0.0028 0.0017 0.0055
Brugia malayi sulfakinin receptor protein 0.0033 0.0024 0.0077
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0029 0.0019 0.0018
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.004 0.0033 0.0566
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0045 0.0039 0.0127
Echinococcus multilocularis neutral alpha glucosidase AB 0.0041 0.0034 0.0033
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0019 0.0004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.004 0.0033 0.0106
Brugia malayi putative neuropeptide receptor 0.0033 0.0024 0.0077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0446 0.057 0.0908
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0012 0.0108
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0062 0.0062 0.0199
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0024 0.0038
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0001 0.0003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0024 0.0024
Brugia malayi MH2 domain containing protein 0.0115 0.0132 0.0427
Brugia malayi MH1 domain containing protein 0.0115 0.0132 0.0427
Trichomonas vaginalis D-aminoacylase, putative 0.019 0.0232 0.2746
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.026 0.0839
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0017
Echinococcus multilocularis fibrillin 1 0.0028 0.0017 0.0017
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0017 0.0154
Echinococcus granulosus chromobox protein 1 0.0147 0.0175 0.0278
Schistosoma mansoni alpha-glucosidase 0.0158 0.0189 0.0301
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.004 0.0033 0.0105
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0019 0.0005 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0017 0.0107
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0001 0.0001
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0019 0.0005 0.0008
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0012 0.0038
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0045 0.0039 0.0128
Brugia malayi Melibiase family protein 0.0059 0.0058 0.0188
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0102 0.0115 0.037
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0017 0.0154
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0055 0.0052 0.1028
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0004 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0007 0.0023
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0024 0.0024
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0025 0.0039
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0012 0.0019
Leishmania major importin beta-1 subunit, putative 0.0044 0.0038 0.0122
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0094 0.0586
Schistosoma mansoni hypothetical protein 0.0033 0.0024 0.0038
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.057 0.0736 0.2381
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0088 0.014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0004 0.0012
Echinococcus granulosus muscleblind protein 0.0459 0.0588 0.0935
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0446 0.057 0.057
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0024 0.0078
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0017 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Leishmania major cytochrome p450-like protein 0.0048 0.0043 0.0138
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.003 0.0185
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0359 0.4264
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0046 0.0429
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0001 0.0002
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0071 0.0074 0.0241
Trypanosoma cruzi myosin heavy chain kinase A, putative 0.0623 0.0805 0.2606
Loa Loa (eye worm) fli-1 protein 0.016 0.0192 0.0623
Loa Loa (eye worm) hypothetical protein 0.0104 0.0117 0.038
Echinococcus granulosus GTP binding nuclear protein Ran 0.004 0.0033 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0012 0.0227
Loa Loa (eye worm) hypothetical protein 0.042 0.0537 0.1737
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0024 0.0024
Brugia malayi hypothetical protein 0.0033 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0012
Onchocerca volvulus 0.042 0.0537 0.1777
Loa Loa (eye worm) hypothetical protein 0.0071 0.0074 0.0241
Brugia malayi jmjC domain containing protein 0.0071 0.0074 0.0237
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0024 0.0038
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0579 0.0747 0.2418
Schistosoma mansoni myst-related protein 0.0025 0.0013 0.002
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0012 0.0037
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0029 0.0028
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.003 0.027
Loa Loa (eye worm) hypothetical protein 0.0082 0.0089 0.0287
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0045 0.0039 0.0246
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0061 0.006 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0695
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0024 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0002 0.0006
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0017 0.0027
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.019 0.0232 0.1457
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Mycobacterium ulcerans aldehyde dehydrogenase 0.0817 0.1062 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0052 0.0598
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0024 0.0038
Trichomonas vaginalis beta chain spectrin, putative 0.0023 0.001 0.0091
Brugia malayi SET domain containing protein 0.0031 0.0021 0.0068
Loa Loa (eye worm) hypothetical protein 0.0104 0.0118 0.0382
Mycobacterium leprae putative cytochrome p450 0.0028 0.0017 0.0706
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0029 0.0019 0.0018
Brugia malayi hypothetical protein 0.0041 0.0034 0.0108
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0044 0.0038 0.0429
Mycobacterium ulcerans lipase LipD 0.019 0.0232 0.2179
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0055 0.0052 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0043 0.0036 0.5074
Echinococcus multilocularis neuropeptide s receptor 0.1017 0.1327 0.1327
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0024 0.0038
Entamoeba histolytica hypothetical protein 0.0024 0.0012 0.0191
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0024 0.0078
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0016 0.0001 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0034 0.0377
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0344 0.0436 0.0694
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0014
Trypanosoma brucei RNA helicase, putative 0.0167 0.0201 0.0649
Loa Loa (eye worm) fibroinase 0.0029 0.0019 0.0061
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0032 0.0032
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0088 0.0096 0.0311
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0055 0.0052 0.0168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0068 0.007 0.0816
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.019 0.0232 0.1457
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0061 0.006 0.0194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0019 0.0198
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0045 0.0039 0.5649
Brugia malayi Inositol-1 0.0062 0.0062 0.0199
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0045 0.0039 0.0127
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0024 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0038
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0034 0.0377
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0017 0.0055
Plasmodium vivax pyruvate kinase, putative 0.0029 0.0018 0.0354
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0072 0.0075 0.0243
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0019 0.0004 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0017 0.0107
Plasmodium falciparum thioredoxin reductase 0.0038 0.003 0.0582
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0243 0.0302 0.0975
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0567 0.0731 0.2367
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0043 0.0036 0.068
Echinococcus granulosus pyruvate kinase 0.0029 0.0018 0.0028
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0055 0.0052 0.0168
Trichomonas vaginalis pyruvate kinase, putative 0.0029 0.0018 0.0191
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0024 0.0038
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0019 0.0005 0.0017
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0024 0.0038
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0025 0.0039
Brugia malayi MH2 domain containing protein 0.1689 0.2217 0.7176
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0059
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0099 0.0111 0.1038
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0022 0.0009 0.0014
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0045 0.0039 0.0363
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0017 0.0107
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0025 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.0048 0.0155
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0156 0.0187 0.0187
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0019 0.0004 0.0044
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0012 0.0105
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0019 0.0004 0.0026
Trichomonas vaginalis immunophilin, putative 0.0397 0.0506 0.6016
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0017 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Mycobacterium tuberculosis Probable conserved lipoprotein 0.019 0.0232 0.1457
Leishmania major DNA polymerase kappa, putative 0.0019 0.0005 0.0015
Onchocerca volvulus Huntingtin homolog 0.0506 0.0651 0.2155
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0058
Leishmania major cathepsin L-like protease 0.0029 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0025 0.008
Plasmodium vivax glutathione reductase, putative 0.0038 0.003 0.0582
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0022 0.0009 0.0008
Mycobacterium ulcerans hydrolase 0.0104 0.0117 0.1098
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0078
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.0144 0.023
Brugia malayi Cathepsin L-like precursor 0.0029 0.0019 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.001 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0019 0.0198
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0024 0.0038
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0446 0.057 0.1845

Activities

Activity type Activity value Assay description Source Reference
CC50 (ADMET) = 30216 nM Cytotoxic activity against human MT4 cells by MTT assay ChEMBL. 25418038
IC50 (binding) = 30 nM Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activity ChEMBL. 25418038
IC50 (binding) = 40 nM Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activity ChEMBL. 25418038
IC50 (binding) = 40 nM Inhibition of wild type HIV1 reverse transcriptase V106A mutant assessed as reduction in enzyme activity ChEMBL. 25418038
IC50 (binding) = 220 nM Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activity ChEMBL. 25418038
IC50 (binding) = 3500 nM Inhibition of wild type HIV1 reverse transcriptase Y181I/Y181C mutant assessed as reduction in enzyme activity ChEMBL. 25418038
IC50 (binding) = 3550 nM Inhibition of wild type HIV1 reverse transcriptase Y181I mutant assessed as reduction in enzyme activity ChEMBL. 25418038

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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