Detailed information for compound 1270957

Basic information

Technical information
  • TDR Targets ID: 1270957
  • Name: 1-phenyl-2-[2-[4-[(E)-3-phenylprop-2-enyl]pip erazin-1-yl]benzimidazol-1-yl]ethanone
  • MW: 436.548 | Formula: C28H28N4O
  • H donors: 0 H acceptors: 2 LogP: 5.36 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccccc1)Cn1c(nc2c1cccc2)N1CCN(CC1)C/C=C/c1ccccc1
  • InChi: 1S/C28H28N4O/c33-27(24-13-5-2-6-14-24)22-32-26-16-8-7-15-25(26)29-28(32)31-20-18-30(19-21-31)17-9-12-23-10-3-1-4-11-23/h1-16H,17-22H2/b12-9+
  • InChiKey: OKFKHUSURYSPGT-FMIVXFBMSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-phenyl-2-[2-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]-1-benzimidazolyl]ethanone
  • T5337223
  • MLS001007373
  • SMR000384570

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0083 0.0064 0.0338
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0126 0.0118 0.0331
Plasmodium vivax serine-repeat antigen (SERA), putative 0.033 0.038 0.2089
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0027 0.0018
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0393 0.046 0.1286
Brugia malayi Tachykinin-like peptides receptor 99D 0.0222 0.0242 0.0677
Echinococcus multilocularis carbonyl reductase 1 0.0112 0.0101 0.0282
Echinococcus multilocularis glycoprotein Antigen 5 0.0059 0.0033 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0009 0.0006
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0204 0.0219 0.0611
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0112 0.0101 0.0282
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0037 0.0005 0.0023
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0074 0.0053 0.0147
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0112 0.0101 0.0282
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2832 0.3577 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0204 0.0219 0.1204
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.033 0.038 0.2089
Echinococcus multilocularis steroid dehydrogenase 0.0112 0.0101 0.0282
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0188 0.0199 0.0555
Onchocerca volvulus 0.0054 0.0027 0.0127
Plasmodium vivax steroid dehydrogenase, putative 0.0112 0.0101 0.0543
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0062 0.0038 0.0105
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.064
Echinococcus granulosus dnaJ subfamily B 0.045 0.0533 0.1491
Schistosoma mansoni hypothetical protein 0.0222 0.0242 0.0675
Loa Loa (eye worm) latrophilin receptor protein 2 0.0536 0.0644 0.0841
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0048 0.0019 0.0052
Onchocerca volvulus Cathepsin L homolog 0.033 0.038 0.193
Toxoplasma gondii calcium binding egf domain-containing protein 0.0042 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis dnaJ subfamily B 0.045 0.0533 0.1491
Brugia malayi hypothetical protein 0.0149 0.0148 0.0414
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0996
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis oxidoreductase 0.0112 0.0101 0.0282
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0047 0.013
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0033 0.0092
Echinococcus granulosus expressed conserved protein 0.0074 0.0052 0.0146
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0034 0.0002 0.0005
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0059 0.0033 0.0094
Echinococcus multilocularis tissue type plasminogen activator 0.0122 0.0114 0.0318
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0003 0.0004
Echinococcus granulosus G protein coupled receptor 139 0.0222 0.0242 0.0677
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0101 0.0543
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Echinococcus granulosus Niemann Pick C1 protein 0.0079 0.0058 0.0163
Trichomonas vaginalis glucosylceramidase, putative 0.0204 0.0219 0.1204
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trypanosoma cruzi cysteine proteinase, putative 0.0783 0.0958 0.2676
Echinococcus granulosus adam 0.0272 0.0306 0.0856
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0054 0.0027 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0466 0.0554 0.1546
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0009 0.0041
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0062 0.0038 0.0339
Brugia malayi N-terminal motif family protein 0.0034 0.0002 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.0101 0.0098
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.004 0.0009 0.0024
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0339 0.0391 0.1094
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0128 0.0122 0.0657
Trichomonas vaginalis glucosylceramidase, putative 0.0204 0.0219 0.1204
Onchocerca volvulus 0.1447 0.1807 0.9215
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0112 0.0101 0.0543
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Giardia lamblia Dipeptidyl-peptidase I precursor 0.033 0.038 0.2686
Brugia malayi Cytochrome P450 family protein 0.0068 0.0045 0.0126
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0228 0.0249 0.0326
Giardia lamblia Dipeptidyl-peptidase I precursor 0.033 0.038 0.2686
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Schistosoma mansoni biogenic amine receptor 0.0222 0.0242 0.0675
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0221 0.0241 0.1317
Brugia malayi Papain family cysteine protease containing protein 0.033 0.038 0.1062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0009 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0994 0.1228 0.3433
Brugia malayi Pre-SET motif family protein 0.0574 0.0692 0.1934
Plasmodium falciparum serine repeat antigen 4 0.033 0.038 0.2089
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0034 0.0002 0.0004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0107 0.0095 0.0124
Plasmodium falciparum serine repeat antigen 8 0.033 0.038 0.2089
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0074 0.0053 0.005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Onchocerca volvulus 0.0059 0.0033 0.0162
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1664 0.2085 0.583
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0037 0.0005 0.0023
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0097 0.0082 0.0439
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0996
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.0101 0.0282
Schistosoma mansoni opsin-like receptor 0.0222 0.0242 0.0675
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0055 0.0029 0.015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Schistosoma mansoni survival motor neuron protein 0.0058 0.0032 0.0089
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0112 0.0101 0.0282
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Toxoplasma gondii oxidoreductase, putative 0.0112 0.0101 0.0543
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0017 0.008
Brugia malayi Cathepsin L-like precursor 0.0994 0.1228 0.3434
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0112 0.0101 0.0282
Loa Loa (eye worm) RasGEF domain-containing protein 0.0034 0.0002 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0783 0.0958 0.5299
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Onchocerca volvulus 0.0126 0.0118 0.0596
Trichomonas vaginalis steroid dehydrogenase, putative 0.0112 0.0101 0.0553
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0054 0.0027 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0027 0.0142
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Mycobacterium ulcerans hypothetical protein 0.0074 0.0053 0.0044
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Schistosoma mansoni hypothetical protein 0.0536 0.0644 0.1798
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Onchocerca volvulus 0.1447 0.1807 0.9215
Loa Loa (eye worm) hypothetical protein 0.079 0.0967 0.1264
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0029 0.0143
Schistosoma mansoni ras GTP exchange factor 0.0034 0.0002 0.0003
Echinococcus multilocularis adam 17 protease 0.1707 0.2139 0.5981
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0054 0.0027 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.038 0.2097
Mycobacterium tuberculosis Conserved protein 0.0074 0.0053 0.005
Giardia lamblia Cathepsin L precursor 0.033 0.038 0.2686
Echinococcus multilocularis hyperpolarization activated cyclic 0.0107 0.0095 0.0265
Leishmania major cytochrome p450-like protein 0.0046 0.0017 0.008
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0126 0.0118 0.0329
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0222 0.0242 0.0677
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0009 0.0006
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Brugia malayi cathepsin B-like cysteine proteinase 0.2832 0.3577 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0072 0.005 0.014
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1447 0.1807 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0126 0.0118 0.0329
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.039 0.0457 0.2516
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0074 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Schistosoma mansoni immunophilin 0.0393 0.046 0.1284
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0048 0.0019 0.009
Mycobacterium ulcerans hydrolase 0.079 0.0967 0.0959
Brugia malayi Cathepsin L-like precursor 0.1447 0.1807 0.5052
Echinococcus granulosus hyperpolarization activated cyclic 0.0107 0.0095 0.0265
Giardia lamblia Encystation-specific protease 0.033 0.038 0.2686
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus granulosus WW domain containing oxidoreductase 0.0112 0.0101 0.0282
Trichomonas vaginalis adenylate cyclase type III, putative 0.0037 0.0005 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0864 0.1062 0.2968
Onchocerca volvulus 0.0059 0.0033 0.0162
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0396 0.0465 0.2566
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0188 0.0199 0.0555
Loa Loa (eye worm) hypothetical protein 0.0116 0.0106 0.0139
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0041 0.001 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Onchocerca volvulus 0.0122 0.0114 0.0571
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0156 0.0158 0.0439
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1447 0.1807 1
Brugia malayi N-terminal motif family protein 0.0034 0.0002 0.0005
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0543
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.033 0.038 0.106
Echinococcus granulosus SAM and MBT domain containing protein 0.0035 0.0002 0.0007
Mycobacterium tuberculosis Possible oxidoreductase 0.0112 0.0101 0.0098
Echinococcus multilocularis segment polarity protein dishevelled 0.0048 0.0019 0.0054
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0122 0.0114 0.0613
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) TK/ROR protein kinase 0.0122 0.0114 0.0148
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0222 0.0242 0.0317
Brugia malayi isocitrate dehydrogenase 0.0035 0.0003 0.0008
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Brugia malayi hypothetical protein 0.0118 0.0109 0.0305
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0054 0.0027 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0027 0.0142
Echinococcus granulosus laminin 0.0042 0.0012 0.0034
Onchocerca volvulus Matrix metalloproteinase homolog 0.1438 0.1796 0.9159
Schistosoma mansoni smad 0.0048 0.0019 0.0052
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.033 0.038 0.106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0122 0.0115 0.0625
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0126 0.0118 0.0331
Loa Loa (eye worm) hypothetical protein 0.1159 0.1439 0.1881
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0112 0.0101 0.0282
Echinococcus granulosus Dipeptidyl peptidase 9 0.0128 0.0122 0.034
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0101 0.0277
Toxoplasma gondii calcium binding egf domain-containing protein 0.0042 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0025
Giardia lamblia Hypothetical protein 0.0112 0.0101 0.0624
Schistosoma mansoni dishevelled 0.0048 0.0019 0.0052
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.033 0.038 0.2089
Loa Loa (eye worm) hypothetical protein 0.0355 0.0412 0.0538
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0222 0.0242 0.0677
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0112 0.0101 0.0282
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0044
Brugia malayi Papain family cysteine protease containing protein 0.033 0.038 0.1062
Echinococcus multilocularis carbonyl reductase 1 0.0112 0.0101 0.0282
Brugia malayi hypothetical protein 0.0112 0.0101 0.0282
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0222 0.0242 0.0677
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0101 0.0277
Onchocerca volvulus Cathepsin L homolog 0.1447 0.1807 0.9215
Entamoeba histolytica hypothetical protein 0.0112 0.0101 0.0549
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Brugia malayi Papain family cysteine protease containing protein 0.0783 0.0958 0.2679
Trypanosoma brucei protein kinase A regulatory subunit 0.0074 0.0053 0.0275
Schistosoma mansoni hypothetical protein 0.0451 0.0535 0.1493
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0118 0.0109 0.0143
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Trypanosoma cruzi cysteine peptidase, putative 0.1447 0.1807 0.5049
Brugia malayi Trypsin family protein 0.0059 0.0033 0.0094
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0009 0.0006
Trypanosoma cruzi short chain dehydrogenase, putative 0.0112 0.0101 0.0277
Mycobacterium ulcerans ketoacyl reductase 0.0112 0.0101 0.0092
Giardia lamblia Cysteine protease 0.033 0.038 0.2686
Onchocerca volvulus 0.0112 0.0101 0.0506
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0222 0.0242 0.0677
Brugia malayi Pre-SET motif family protein 0.0083 0.0064 0.0179
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0112 0.0101 0.0553
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0062 0.0038 0.0192
Brugia malayi Cathepsin L-like precursor 0.1447 0.1807 0.5052
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0074 0.0053 0.0143
Brugia malayi Cathepsin L-like cysteine proteinase 0.0994 0.1228 0.3434
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0055 0.0029 0.0154
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0074 0.0053 0.0147
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.0013 0.0035
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Brugia malayi Dopamine receptor protein 1 0.0222 0.0242 0.0677
Onchocerca volvulus 0.0222 0.0242 0.1228
Onchocerca volvulus 0.0222 0.0242 0.1228
Echinococcus granulosus allatostatin A receptor 0.0222 0.0242 0.0677
Echinococcus granulosus carbonyl reductase 1 0.0112 0.0101 0.0282
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0034 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0013 0.0017
Echinococcus granulosus sodium and chloride dependent glycine 0.0126 0.0118 0.0331
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0126 0.0118 0.0331
Echinococcus granulosus cathepsin b 0.2832 0.3577 1
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0224 0.0244 0.068
Brugia malayi putative neuropeptide receptor NPR1 0.0222 0.0242 0.0677
Brugia malayi cathepsin Z-like cysteine proteinase 0.033 0.038 0.1062
Loa Loa (eye worm) serotonin transporter b 0.074 0.0903 0.1181
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0053 0.0145
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0423 0.0498 0.1391
Schistosoma mansoni niemann-pick C1 (NPC1) 0.008 0.006 0.0166
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0112 0.0101 0.0549
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.0155
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.1447 0.1807 1
Onchocerca volvulus 0.0222 0.0242 0.1228
Loa Loa (eye worm) hypothetical protein 0.0107 0.0095 0.0124
Schistosoma mansoni smad1 5 8 and 0.0048 0.0019 0.0052
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0222 0.0242 0.0675
Onchocerca volvulus 0.0222 0.0242 0.1228
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1104 0.1369 0.7573
Entamoeba histolytica hypothetical protein 0.0065 0.0041 0.0216
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0074 0.0053 0.0275
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0112 0.0101 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.2389 0.3011 0.8418
Trichomonas vaginalis adenylate cyclase type, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0107 0.0095 0.0518
Echinococcus multilocularis neuropeptide s receptor 0.0778 0.0952 0.2662
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.0198 0.0189
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0044
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.039 0.0457 0.1273
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0222 0.0242 0.0675
Trypanosoma cruzi cruzipain precursor, putative 0.1447 0.1807 0.5049
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Echinococcus multilocularis smad 0.0048 0.0019 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0118 0.0109 0.0589
Loa Loa (eye worm) hypothetical protein 0.033 0.038 0.0496
Mycobacterium ulcerans ketoacyl reductase 0.0112 0.0101 0.0092
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.0126
Echinococcus granulosus single minded 2 0.0037 0.0005 0.0014
Loa Loa (eye worm) G-protein coupled receptor 0.0222 0.0242 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0009 0.0006
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Leishmania major short chain dehydrogenase/reductase, putative 0.0112 0.0101 0.0543
Loa Loa (eye worm) RasGEF domain-containing protein 0.0034 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.2832 0.3577 0.4674
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0074 0.0053 0.0145
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Loa Loa (eye worm) hypothetical protein 0.0054 0.0027 0.0035
Echinococcus granulosus steroid dehydrogenase 0.0112 0.0101 0.0282
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0107 0.0095 0.0265
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0079 0.0059 0.0166
Echinococcus granulosus voltage gated potassium channel 0.0144 0.0142 0.0396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.033 0.038 0.2097
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0112 0.0101 0.028
Schistosoma mansoni cathepsin C 0.033 0.038 0.106
Echinococcus multilocularis sex peptide receptor 0.0222 0.0242 0.0677
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0009 0.0006
Entamoeba histolytica cysteine protease, putative 0.1447 0.1807 1
Echinococcus multilocularis carbonyl reductase 1 0.0112 0.0101 0.0282
Toxoplasma gondii hypothetical protein 0.0126 0.0118 0.064
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0783 0.0958 0.5296
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Toxoplasma gondii aldehyde dehydrogenase 0.0187 0.0198 0.1078
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Loa Loa (eye worm) G-protein coupled receptor 0.0222 0.0242 0.0317
Onchocerca volvulus 0.0059 0.0033 0.0162
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.2389 0.3011 0.8418
Loa Loa (eye worm) hypothetical protein 0.0188 0.0199 0.026
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0074 0.0053 0.0275
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.033 0.038 0.2089
Schistosoma mansoni hypothetical protein 0.1159 0.1439 0.4023
Loa Loa (eye worm) Smad1 0.0048 0.0019 0.0025
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0107 0.0095 0.0265
Schistosoma mansoni retinal dehydrogenase 0.0112 0.0101 0.028
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0222 0.0242 0.0677
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0165 0.0169 0.0473
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0126 0.0118 0.0329
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0037 0.0005 0.0023
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0551 0.0662 0.1849
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0042 0.0012 0.0032
Giardia lamblia Cysteine protease 0.033 0.038 0.2686
Loa Loa (eye worm) prolyl oligopeptidase 0.0226 0.0247 0.0322
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0009 0.0006
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0054 0.0027 0.0035
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1447 0.1807 0.2361
Giardia lamblia Reductase, putative 0.0112 0.0101 0.0624
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0017 0.0044
Brugia malayi Probable ClpP-like protease 0.0062 0.0038 0.0105
Mycobacterium ulcerans short-chain type oxidoreductase 0.0112 0.0101 0.0092
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0222 0.0242 0.0677
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis cpg binding protein 0.0033 0.0001 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0222 0.0242 0.0677
Mycobacterium ulcerans oxidoreductase 0.0112 0.0101 0.0092
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Onchocerca volvulus 0.033 0.038 0.193
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.0095 0.0263
Entamoeba histolytica hypothetical protein 0.0065 0.0041 0.0216
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Schistosoma mansoni amine GPCR 0.1131 0.1404 0.3924
Onchocerca volvulus 0.0222 0.0242 0.1228
Onchocerca volvulus 0.0492 0.0586 0.2985
Brugia malayi hypothetical protein 0.0112 0.0101 0.0282
Schistosoma mansoni hypothetical protein 0.0222 0.0242 0.0675
Schistosoma mansoni hypothetical protein 0.004 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0536 0.0644 0.0841
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Loa Loa (eye worm) hypothetical protein 0.0086 0.0068 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Brugia malayi glutaminase DH11.1 0.0172 0.0178 0.0497
Schistosoma mansoni tar DNA-binding protein 0.0864 0.1062 0.2968
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0144 0.0142 0.0185
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0128 0.0122 0.0657
Loa Loa (eye worm) dehydrogenase 0.0112 0.0101 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.038 0.2097
Toxoplasma gondii LsmAD domain-containing protein 0.0118 0.0109 0.0589
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0994 0.1228 0.3431
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Plasmodium vivax vivapain-1 0.0783 0.0958 0.5296
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0543
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0009 0.0006
Brugia malayi RasGEF domain containing protein 0.0034 0.0002 0.0005
Echinococcus granulosus patatin phospholipase domain containing protein 0.0074 0.0053 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0079 0.0219
Echinococcus multilocularis cathepsin L 0.033 0.038 0.1062
Loa Loa (eye worm) hypothetical protein 0.0116 0.0106 0.0139
Loa Loa (eye worm) hypothetical protein 0.0062 0.0038 0.0049
Trypanosoma brucei cAMP binding protein, putative 0.0074 0.0053 0.0275
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0065 0.0041 0.0114
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0112 0.0101 0.0549
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.033 0.038 0.2686
Schistosoma mansoni growth hormone secretagogue receptor 0.0222 0.0242 0.0675
Brugia malayi Melatonin receptor type 1A 0.0222 0.0242 0.0677
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0054 0.0027 0.0138
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.033 0.038 0.2089
Brugia malayi hypothetical protein 0.0059 0.0033 0.0094
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0042 0.0012 0.0034
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0055 0.0029 0.0298
Loa Loa (eye worm) hypothetical protein 0.0122 0.0114 0.0148
Loa Loa (eye worm) hypothetical protein 0.074 0.0903 0.1181
Plasmodium falciparum serine repeat antigen 3 0.033 0.038 0.2089
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0074 0.0053 0.005
Schistosoma mansoni hypothetical protein 0.0054 0.0027 0.0073
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Trypanosoma brucei DNA polymerase IV, putative 0.0051 0.0024 0.0115
Giardia lamblia Cathepsin B precursor 0.033 0.038 0.2686
Schistosoma mansoni cathepsin s 0.0453 0.0537 0.1498
Onchocerca volvulus 0.1447 0.1807 0.9215
Schistosoma mansoni neuropeptide receptor 0.0222 0.0242 0.0675
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Loa Loa (eye worm) inositol-1 0.0055 0.0029 0.0038
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0038 0.0196
Mycobacterium leprae Conserved hypothetical protein 0.0074 0.0053 0.0494
Echinococcus granulosus carbonyl reductase 1 0.0112 0.0101 0.0282
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0112 0.0101 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Echinococcus multilocularis retinol dehydrogenase 13 0.0112 0.0101 0.0282
Echinococcus multilocularis SAM and MBT domain containing protein 0.0035 0.0002 0.0007
Onchocerca volvulus Neuropeptide F receptor homolog 0.0222 0.0242 0.1228
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0054 0.0027 0.0131
Echinococcus granulosus transmembrane protease serine 3 0.0059 0.0033 0.0094
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0112 0.0101 0.0282
Entamoeba histolytica cysteine proteinase, putative 0.1447 0.1807 1
Leishmania major cyclic nucleotide-binding protein-like protein 0.0074 0.0053 0.0275
Echinococcus multilocularis allatostatin A receptor 0.0222 0.0242 0.0677
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0112 0.0101 0.0098
Trypanosoma cruzi short chain dehydrogenase, putative 0.0112 0.0101 0.0277
Brugia malayi Fibulin-1 precursor 0.0042 0.0012 0.0034
Onchocerca volvulus 0.0112 0.0101 0.0506
Mycobacterium ulcerans ketoacyl reductase 0.0112 0.0101 0.0092
Echinococcus multilocularis g protein coupled receptor 0.0222 0.0242 0.0677
Echinococcus granulosus Mastin 0.0059 0.0033 0.0094
Plasmodium falciparum serine repeat antigen 1 0.033 0.038 0.2089
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0074 0.0053 0.0143
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0091 0.0074 0.0393
Echinococcus granulosus tar DNA binding protein 0.0864 0.1062 0.2969
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Echinococcus multilocularis g protein coupled receptor 0.0222 0.0242 0.0677
Brugia malayi hypothetical protein 0.0065 0.0041 0.0114
Onchocerca volvulus 0.0112 0.0101 0.0506
Schistosoma mansoni patched 1 0.0034 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.033 0.038 0.0496
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Echinococcus multilocularis sterol regulatory element binding protein 0.0034 0.0001 0.0003
Loa Loa (eye worm) RasGEF domain-containing protein 0.0034 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Toxoplasma gondii oxidoreductase, putative 0.0112 0.0101 0.0543
Onchocerca volvulus 0.1447 0.1807 0.9215
Giardia lamblia Fructose-bisphosphate aldolase 0.0122 0.0115 0.0724
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0222 0.0242 0.0677
Brugia malayi Dopamine receptor 0.0222 0.0242 0.0677
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Trypanosoma cruzi cysteine peptidase, putative 0.1447 0.1807 0.5049
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0222 0.0242 0.0675
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0222 0.0242 0.0677
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0027 0.0135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Loa Loa (eye worm) hypothetical protein 0.033 0.038 0.0496
Plasmodium vivax vivapain-2 0.1447 0.1807 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0074 0.0053 0.0147
Onchocerca volvulus 0.0222 0.0242 0.1228
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0074 0.0053 0.0147
Echinococcus granulosus fmrfamide receptor 0.0222 0.0242 0.0677
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0079 0.0219
Echinococcus granulosus g protein coupled receptor 0.0222 0.0242 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0156 0.0158 0.0439
Echinococcus granulosus oxidoreductase 0.0112 0.0101 0.0282
Giardia lamblia Cathepsin L precursor 0.033 0.038 0.2686
Echinococcus granulosus hypothetical protein 0.0112 0.0101 0.0282
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.039 0.0457 0.1276
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0033 0.0092
Loa Loa (eye worm) FKBP5 protein 0.039 0.0457 0.0597
Echinococcus multilocularis isocitrate dehydrogenase 0.0035 0.0003 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0222 0.0242 0.0675
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0118 0.0109 0.0589
Echinococcus granulosus histone acetyltransferase MYST2 0.004 0.0009 0.0024
Schistosoma mansoni immunophilin 0.0339 0.0391 0.1092
Giardia lamblia Cathepsin L precursor 0.033 0.038 0.2686
Mycobacterium leprae putative cytochrome p450 0.004 0.0009 0.0041
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Brugia malayi Matrixin family protein 0.0648 0.0787 0.2199
Loa Loa (eye worm) hypothetical protein 0.0042 0.0012 0.0016
Leishmania major cysteine peptidase A (CPA) 0.1447 0.1807 1
Brugia malayi dehydrogenases, short chain protein 2 0.0112 0.0101 0.0282
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0175 0.0182 0.0179
Echinococcus granulosus GPCR family 2 0.0536 0.0644 0.1799
Loa Loa (eye worm) hypothetical protein 0.0453 0.0537 0.0701
Echinococcus granulosus cathepsin L 0.033 0.038 0.1062
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0101 0.0277
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0054 0.0027 0.0075
Echinococcus multilocularis neuropeptide receptor 0.0301 0.0343 0.0959
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1447 0.1807 0.5052
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.0138
Leishmania major 3-keto-dihydrosphingosine reductase 0.0112 0.0101 0.0543
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0126 0.0118 0.0331
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0222 0.0242 0.0677
Schistosoma mansoni neuropeptide receptor 0.0222 0.0242 0.0675
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Onchocerca volvulus 0.0149 0.0148 0.0747
Entamoeba histolytica cysteine protease, putative 0.033 0.038 0.2094
Echinococcus granulosus Pleckstrin G protein interacting region 0.0048 0.0019 0.0054
Echinococcus granulosus cathepsin L cysteine protease 0.0783 0.0958 0.2679
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0165 0.0169 0.0221
Echinococcus multilocularis neuropeptide FF receptor 2 0.0222 0.0242 0.0677
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Onchocerca volvulus 0.0653 0.0793 0.4039
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Brugia malayi DIX domain containing protein 0.0048 0.0019 0.0054
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0112 0.0101 0.0553
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0054 0.0027 0.007
Trichomonas vaginalis glucosylceramidase, putative 0.0204 0.0219 0.1204
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0083 0.0064 0.0177
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0041 0.001 0.0007
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0042 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.0212 0.0228 0.0637
Trichomonas vaginalis adenylate cyclase type III, putative 0.0037 0.0005 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Schistosoma mansoni hypothetical protein 0.0122 0.0114 0.0316
Brugia malayi AKH receptor 0.0222 0.0242 0.0677
Mycobacterium leprae PROBABLE HYDROLASE 0.079 0.0967 1
Mycobacterium ulcerans dehydrogenase/reductase 0.0112 0.0101 0.0092
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Entamoeba histolytica hypothetical protein, conserved 0.0112 0.0101 0.0549
Loa Loa (eye worm) RNA binding protein 0.0864 0.1062 0.1388
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.0029
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.039 0.0457 0.2516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0222 0.0242 0.0677
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0074 0.0053 0.0147
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0074 0.0053 0.0147
Echinococcus granulosus neuropeptide s receptor 0.0778 0.0952 0.2662
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.033 0.038 0.2097
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0074 0.0053 0.0147
Echinococcus granulosus polycomb protein SCMH1 0.0035 0.0002 0.0007
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0393 0.046 0.1286
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0112 0.0101 0.0543
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1695 0.2125 0.2777
Leishmania major fk506-binding protein 1-like protein 0.039 0.0457 0.2516
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0101 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0053 0.0286
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Echinococcus granulosus Tolloid protein 1 0.0042 0.0012 0.0034
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0117 0.0108 0.1066
Echinococcus multilocularis Mastin 0.0059 0.0033 0.0094
Echinococcus granulosus cathepsin b 0.2832 0.3577 1
Entamoeba histolytica short chain dehydrogenase family protein 0.0112 0.0101 0.0549
Schistosoma mansoni hypothetical protein 0.0536 0.0644 0.1798
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0126 0.0118 0.0329
Echinococcus granulosus neuropeptide Y receptor 0.0222 0.0242 0.0677
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0222 0.0242 0.1228
Schistosoma mansoni DNA polymerase eta 0.0043 0.0013 0.0035
Onchocerca volvulus 0.0059 0.0033 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Plasmodium falciparum serine repeat antigen 9 0.033 0.038 0.2089
Schistosoma mansoni neuropeptide f receptor 76f 0.0222 0.0242 0.0675
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0222 0.0242 0.0675
Trypanosoma brucei unspecified product 0.0051 0.0024 0.0115
Mycobacterium leprae Probable oxidoreductase 0.0112 0.0101 0.0996
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0009 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0222 0.0242 0.0677
Schistosoma mansoni opsin-like receptor 0.0222 0.0242 0.0675
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0083 0.0064 0.0177
Plasmodium vivax vivapain-2 0.1447 0.1807 1
Plasmodium vivax serine-repeat antigen (SERA) 0.033 0.038 0.2089
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis orexin receptor type 2 0.0222 0.0242 0.0677
Giardia lamblia Cathepsin B precursor 0.1104 0.1369 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0074 0.0053 0.0147
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0055 0.0029 0.002
Brugia malayi Serotonin receptor 0.0222 0.0242 0.0677
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.033 0.038 0.2089
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.0013 0.0063
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.006 0.0034 0.0031
Echinococcus multilocularis 0.0054 0.0027 0.0075
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0536 0.0644 0.1799
Trypanosoma cruzi protein kinase A regulatory subunit 0.0074 0.0053 0.0143
Mycobacterium ulcerans transcriptional regulatory protein 0.0074 0.0053 0.0044
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0222 0.0242 0.0677
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0222 0.0242 0.0675
Brugia malayi Egg laying defective protein 4 0.0074 0.0053 0.0147
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0054 0.0027 0.0035
Plasmodium falciparum serine repeat antigen 7 0.033 0.038 0.2089
Trichomonas vaginalis glutaminase, putative 0.0172 0.0178 0.0978
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Brugia malayi hypothetical protein 0.0048 0.0019 0.0054
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0037 0.0005 0.0023
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0074 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Mycobacterium ulcerans hypothetical protein 0.0059 0.0033 0.0024
Echinococcus multilocularis regulator of G protein signaling 7 0.0048 0.0019 0.0054
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Brugia malayi GnHR receptor homolog 0.1642 0.2057 0.5751
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0222 0.0242 0.0675
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0112 0.0101 0.0624
Schistosoma mansoni carbonyl reductase 0.0112 0.0101 0.028
Trichomonas vaginalis adenylate cyclase type, putative 0.0037 0.0005 0.0023
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0112 0.0101 0.0277
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.033 0.038 0.2089
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0054 0.0027 0.007
Onchocerca volvulus 0.0112 0.0101 0.0506
Echinococcus granulosus FK506 binding protein 2 0.0054 0.0027 0.0075
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0033 0.0092
Schistosoma mansoni hypothetical protein 0.0536 0.0644 0.1798
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0017 0.0075
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0074 0.0053 0.0145
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Brugia malayi G-protein coupled receptor 0.0222 0.0242 0.0677
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0037 0.0005 0.0023
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0034 0.0002 0.0003
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0107 0.0095 0.0265
Mycobacterium ulcerans epoxide hydrolase EphA 0.0194 0.0206 0.0197
Plasmodium falciparum serine repeat antigen 6 0.033 0.038 0.2089
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0054 0.0027 0.0145
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0222 0.0242 0.0677
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.0013 0.0017
Echinococcus multilocularis cysteine protease 0.1447 0.1807 0.5052
Echinococcus multilocularis sodium channel protein 0.0091 0.0074 0.0206
Loa Loa (eye worm) hypothetical protein 0.0453 0.0537 0.0701
Echinococcus granulosus ras GTP exchange factor 0.0034 0.0002 0.0005
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.033 0.038 0.2097
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0054 0.0027 0.0224
Echinococcus multilocularis fibrillin 1 0.0042 0.0012 0.0034
Loa Loa (eye worm) glutaminase 2 0.0172 0.0178 0.0232
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0095 0.0263
Plasmodium falciparum cGMP-dependent protein kinase 0.0074 0.0053 0.0275
Schistosoma mansoni hypothetical protein 0.0053 0.0026 0.007
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) solute carrier family 6 member 4 0.074 0.0903 0.1181
Loa Loa (eye worm) hypothetical protein 0.0337 0.0388 0.0507
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0466 0.0554 0.1546
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0112 0.0101 0.0543
Leishmania major DNA polymerase kappa, putative 0.0046 0.0017 0.0075
Schistosoma mansoni histamine h1 receptor 0.0222 0.0242 0.0675
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.033 0.038 0.106
Echinococcus granulosus neuropeptides capa receptor 0.0222 0.0242 0.0677
Brugia malayi fibroinase precursor 0.033 0.038 0.1062
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0074 0.0053 0.0145
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0222 0.0242 0.0677
Brugia malayi Smad1 0.0048 0.0019 0.0054
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus multilocularis segment polarity protein dishevelled 0.0048 0.0019 0.0054
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0226 0.0247 0.069
Loa Loa (eye worm) AGC/PKG protein kinase 0.0074 0.0053 0.0069
Echinococcus granulosus hypothetical protein 0.0112 0.0101 0.0282
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0429 0.0506 0.1416
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0009 0.0021
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0112 0.0101 0.0506
Echinococcus granulosus Smad4 0.0048 0.0019 0.0054
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis fk506-binding protein, putative 0.0054 0.0027 0.0142
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.033 0.038 0.2097
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.006 0.0034 0.0025
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0053 0.0275
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0042 0.0012 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Entamoeba histolytica hypothetical protein 0.0065 0.0041 0.0216
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0059 0.0033 0.0092
Brugia malayi RNA binding protein 0.0864 0.1062 0.2969
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0074 0.0053 0.0147
Echinococcus multilocularis regulator of G protein signaling 7 0.0048 0.0019 0.0054
Trypanosoma brucei short-chain dehydrogenase, putative 0.0112 0.0101 0.0543
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0107 0.0095 0.0263
Echinococcus multilocularis Niemann Pick C1 protein 0.0112 0.0101 0.0284
Trypanosoma cruzi cysteine protease, putative 0.0783 0.0958 0.2676
Schistosoma mansoni voltage-gated potassium channel 0.0144 0.0142 0.0395
Onchocerca volvulus 0.0112 0.0101 0.0506
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0112 0.0101 0.0549
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0112 0.0101 0.0092
Echinococcus granulosus orexin receptor type 2 0.0222 0.0242 0.0677
Schistosoma mansoni immunophilin 0.0393 0.046 0.1284
Echinococcus multilocularis somatostatin receptor 0.0222 0.0242 0.0677
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0112 0.0101 0.0543
Onchocerca volvulus 0.0222 0.0242 0.1228
Echinococcus multilocularis dro:myosuppressin receptor 0.0222 0.0242 0.0677
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Brugia malayi hypothetical protein 0.0074 0.0053 0.0148
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0222 0.0242 0.0677
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0112 0.0101 0.0543
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.039 0.0457 0.1273
Brugia malayi hypothetical protein 0.0076 0.0056 0.0155
Echinococcus granulosus glycoprotein Antigen 5 0.0059 0.0033 0.0094
Schistosoma mansoni hypothetical protein 0.0222 0.0242 0.0675
Brugia malayi Trypsin family protein 0.0551 0.0662 0.185
Brugia malayi Calcium binding EGF domain containing protein 0.0042 0.0012 0.0034
Trypanosoma brucei cysteine peptidase C (CPC) 0.1104 0.1369 0.757
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.0013 0.0035
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0144 0.0142 0.0396
Echinococcus multilocularis neuropeptide receptor A26 0.0778 0.0952 0.2662
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2832 0.3577 1
Echinococcus granulosus neuropeptide receptor 0.0222 0.0242 0.0677
Onchocerca volvulus Cathepsin L homolog 0.1447 0.1807 0.9215
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0453 0.0537 0.0701
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0126 0.0118 0.0331
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Loa Loa (eye worm) cathepsin B 0.1104 0.1369 0.1788
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Brugia malayi Papain family cysteine protease containing protein 0.1447 0.1807 0.5052
Plasmodium vivax serine-repeat antigen (SERA) 0.033 0.038 0.2089
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0112 0.0101 0.0092
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0112 0.0101 0.0506
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0222 0.0242 0.0677
Echinococcus granulosus smad 0.0048 0.0019 0.0054
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Brugia malayi mbt repeat family protein 0.0035 0.0002 0.0007
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0806 0.0988 0.2762
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.039 0.0457 0.2516
Loa Loa (eye worm) TAR-binding protein 0.0864 0.1062 0.1388
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0783 0.0958 0.2676
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0117 0.0108 0.0105
Onchocerca volvulus 0.0222 0.0242 0.1228
Echinococcus granulosus 7tm_1 domain containing protein 0.0222 0.0242 0.0677
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0188 0.0199 0.0553
Brugia malayi angiogenesis inhibito 0.0116 0.0106 0.0298
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0429 0.0506 0.1416
Brugia malayi Trypsin family protein 0.0059 0.0033 0.0094
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.039 0.0457 0.1277
Echinococcus multilocularis Smad4 0.0048 0.0019 0.0054
Schistosoma mansoni cathepsin B (C01 family) 0.033 0.038 0.106
Echinococcus multilocularis serotonin transporter 0.074 0.0903 0.2526
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Onchocerca volvulus 0.0126 0.0118 0.0596
Trypanosoma brucei short-chain dehydrogenase, putative 0.0112 0.0101 0.0543
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Echinococcus multilocularis fmrfamide receptor 0.0222 0.0242 0.0677
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.033 0.038 0.2097
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.033 0.038 0.2089
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Loa Loa (eye worm) matrix metalloproteinase 0.0648 0.0787 0.1028
Echinococcus granulosus serotonin transporter 0.074 0.0903 0.2526
Brugia malayi cathepsin Z-like cysteine proteinase 0.033 0.038 0.1062
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0138 0.0759
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0053 0.0286
Brugia malayi Trypsin family protein 0.0059 0.0033 0.0094
Leishmania major cytochrome p450-like protein 0.004 0.0009 0.0034
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0112 0.0101 0.0277
Echinococcus granulosus neuropeptides capa receptor 0.0222 0.0242 0.0677
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0112 0.0101 0.0282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2832 0.3577 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.033 0.038 0.106
Echinococcus granulosus neuropeptide FF receptor 2 0.0222 0.0242 0.0677
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.039 0.0457 0.2516
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Brugia malayi cathepsin L-like precursor 0.0994 0.1228 0.3434
Onchocerca volvulus 0.0222 0.0242 0.1228
Echinococcus multilocularis Niemann Pick C1 protein 0.0079 0.0058 0.0163
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.039 0.0457 0.1277
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0126 0.0118 0.0329
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1695 0.2125 0.5941
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0112 0.0101 0.0543
Trichomonas vaginalis inositol monophosphatase, putative 0.0055 0.0029 0.0154
Trypanosoma cruzi cruzipain precursor, putative 0.0453 0.0537 0.1496
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0806 0.0988 0.2762
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0188 0.0199 0.0555
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1447 0.1807 0.5052
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0536 0.0644 0.1799
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Giardia lamblia Cathepsin L precursor 0.033 0.038 0.2686
Giardia lamblia Short-chain dehydrogenase, putative 0.0112 0.0101 0.0624
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0112 0.0101 0.0098
Loa Loa (eye worm) hypothetical protein 0.0041 0.0011 0.0014
Echinococcus multilocularis cysteine protease 0.1447 0.1807 0.5052
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0126 0.0118 0.0329
Echinococcus multilocularis protein dispatched 1 0.0038 0.0007 0.002
Echinococcus multilocularis snurportin 1 0.0228 0.0249 0.0697
Echinococcus granulosus enteropeptidase 0.0059 0.0033 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Mycobacterium ulcerans oxidoreductase 0.0112 0.0101 0.0092
Echinococcus multilocularis inositol monophosphatase 1 0.0055 0.0029 0.0081
Echinococcus multilocularis peptidase Clp (S14 family) 0.0041 0.001 0.0029
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.1206
Onchocerca volvulus 0.0074 0.0053 0.026
Loa Loa (eye worm) neuropeptide F receptor 0.0222 0.0242 0.0317
Echinococcus multilocularis g protein coupled receptor 0.0222 0.0242 0.0677
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0048 0.0019 0.0054
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Brugia malayi Matrixin family protein 0.0648 0.0787 0.2199
Loa Loa (eye worm) hypothetical protein 0.0054 0.0027 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Echinococcus multilocularis fk506 binding protein 0.039 0.0457 0.1277
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0035 0.0002 0.0005
Schistosoma mansoni amine GPCR 0.0222 0.0242 0.0675
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0543
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0187 0.0198 0.1078
Echinococcus multilocularis enteropeptidase 0.0059 0.0033 0.0094
Loa Loa (eye worm) hypothetical protein 0.0034 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Echinococcus granulosus Niemann Pick C1 protein 0.0112 0.0101 0.0284
Schistosoma mansoni hypothetical protein 0.0536 0.0644 0.1798
Brugia malayi Isocitrate dehydrogenase 0.0035 0.0003 0.0008
Echinococcus granulosus peptide allatostatin:somatostatin 0.0222 0.0242 0.0677
Brugia malayi dehydrogenases, short chain protein 9 0.0112 0.0101 0.0282
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0003 0.0008
Brugia malayi mbt repeat family protein 0.0035 0.0002 0.0007
Brugia malayi putative neuropeptide receptor 0.0222 0.0242 0.0677
Loa Loa (eye worm) hypothetical protein 0.6021 0.7653 1
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Plasmodium vivax unspecified product 0.0453 0.0537 0.2958
Loa Loa (eye worm) hypothetical protein 0.074 0.0903 0.1181
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0222 0.0242 0.0675
Echinococcus multilocularis tar DNA binding protein 0.0864 0.1062 0.2969
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis mothers against decapentaplegic 5 0.0048 0.0019 0.0054
Giardia lamblia Cathepsin L precursor 0.033 0.038 0.2686
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0112 0.0101 0.0506
Brugia malayi MH2 domain containing protein 0.0048 0.0019 0.0054
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis disintegrin and metalloproteinase 0.0266 0.0298 0.0834
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.007
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0055 0.0029 0.0154
Toxoplasma gondii kringle domain-containing protein 0.0122 0.0114 0.0613
Echinococcus granulosus dna polymerase kappa 0.0054 0.0027 0.0076
Brugia malayi Cathepsin L-like precursor 0.0994 0.1228 0.3434
Trichomonas vaginalis fk506-binding protein, putative 0.039 0.0457 0.2524
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.0155
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Treponema pallidum cyclic nucleotide binding protein 0.0074 0.0053 0.0297
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.1707 0.2139 0.598
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Brugia malayi Trypsin-like protease protein 5 0.0059 0.0033 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0101 0.0277
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0128 0.0122 0.0657
Loa Loa (eye worm) hypothetical protein 0.0074 0.0053 0.0069
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Brugia malayi latrophilin 2 splice variant baaae 0.1159 0.1439 0.4024
Loa Loa (eye worm) MH2 domain-containing protein 0.0048 0.0019 0.0025
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0112 0.0101 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0126 0.0118 0.064
Echinococcus granulosus disintegrin and metalloproteinase 0.0266 0.0298 0.0834
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0112 0.0101 0.028
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0009 0.0021
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0074 0.0053 0.0069
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.039 0.0457 0.2524
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0128 0.0122 0.0338
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0053 0.0275
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus granulosus neuropeptide receptor 0.0301 0.0343 0.0959
Echinococcus multilocularis ras GTP exchange factor 0.0034 0.0002 0.0005
Loa Loa (eye worm) matrixin family protein 0.1438 0.1796 0.2347
Onchocerca volvulus Glucosylceramidase homolog 0.0134 0.0129 0.0649
Schistosoma mansoni biogenic amine receptor 0.0222 0.0242 0.0675
Entamoeba histolytica cysteine proteinase 1, putative 0.0783 0.0958 0.5299
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Schistosoma mansoni hypothetical protein 0.0065 0.0041 0.0112
Brugia malayi neuropeptide F receptor 0.0222 0.0242 0.0677
Onchocerca volvulus 0.0112 0.0101 0.0506
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Trypanosoma cruzi cysteine peptidase, putative 0.0783 0.0958 0.2676
Trypanosoma cruzi cAMP response protein 1, putative 0.0074 0.0053 0.0143
Echinococcus granulosus mothers against decapentaplegic 5 0.0048 0.0019 0.0054
Echinococcus multilocularis voltage gated potassium channel 0.0144 0.0142 0.0396
Schistosoma mansoni z-protein (S1r protein) 0.0048 0.0019 0.0052
Loa Loa (eye worm) cysteine protease 0.1447 0.1807 0.2361
Onchocerca volvulus 0.0222 0.0242 0.1228
Brugia malayi regulator of G-protein signaling egl-10 0.0048 0.0019 0.0054
Echinococcus granulosus alpha 1A adrenergic receptor 0.0222 0.0242 0.0677
Trichomonas vaginalis DNA polymerase eta, putative 0.0054 0.0027 0.0145
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0079 0.0103
Trypanosoma cruzi PAB1-binding protein , putative 0.0118 0.0109 0.0301
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0054 0.0027 0.0131
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0783 0.0958 0.5301
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0074 0.0053 0.0286
Brugia malayi Latrophilin receptor protein 2 0.0536 0.0644 0.1799
Echinococcus granulosus hyperpolarization activated cyclic 0.0107 0.0095 0.0265
Leishmania major protein kinase, putative 0.0074 0.0053 0.0275
Schistosoma mansoni amine GPCR 0.0222 0.0242 0.0675
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0079 0.0221
Brugia malayi cathepsin L-like cysteine proteinase 0.033 0.038 0.1062
Schistosoma mansoni carbonyl reductase 0.0112 0.0101 0.028
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0112 0.0101 1
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0101 0.0277
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.038 0.2097
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0048 0.0019 0.0054
Mycobacterium ulcerans short chain dehydrogenase 0.0117 0.0108 0.0099
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0222 0.0242 0.0677
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Leishmania major cytochrome p450-like protein 0.004 0.0009 0.0034
Leishmania major short chain dehydrogenase, putative 0.0112 0.0101 0.0543
Loa Loa (eye worm) MH1 domain-containing protein 0.0048 0.0019 0.0025
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0042 0.0012 0.0016
Brugia malayi Matrixin family protein 0.0648 0.0787 0.2199
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Loa Loa (eye worm) mbt repeat family protein 0.0035 0.0002 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0027 0.0072
Brugia malayi MH1 domain containing protein 0.0048 0.0019 0.0054
Toxoplasma gondii preprocathepsin c precursor, putative 0.033 0.038 0.2089
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1447 0.1807 0.2361
Loa Loa (eye worm) MBCTL1 0.004 0.0009 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0009 0.0006
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0027 0.0018
Brugia malayi neuropeptide F receptor 0.0222 0.0242 0.0677
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.039 0.0457 0.3257
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0112 0.0101 0.0543
Mycobacterium ulcerans regulatory protein 0.0074 0.0053 0.0044
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0783 0.0958 0.2678
Onchocerca volvulus Arrow homolog 0.0042 0.0012 0.0053
Giardia lamblia Hypothetical protein 0.033 0.038 0.2686
Giardia lamblia Hypothetical protein 0.033 0.038 0.2686
Echinococcus granulosus cathepsin l cysteine peptidase 0.1447 0.1807 0.5052
Plasmodium vivax unspecified product 0.0783 0.0958 0.5296
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.033 0.038 0.2089
Brugia malayi CHE-14 protein 0.0034 0.0001 0.0003
Echinococcus multilocularis cathepsin L cysteine protease 0.1447 0.1807 0.5052
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.039 0.0457 0.1273
Onchocerca volvulus 0.0035 0.0002 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1104 0.1369 0.3825
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Brugia malayi G-protein coupled receptor 0.0222 0.0242 0.0677
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.0331
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0045 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Brugia malayi G protein-coupled receptor 0.0222 0.0242 0.0677
Schistosoma mansoni hypothetical protein 0.0074 0.0053 0.0145
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0112 0.0101 0.0996
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0783 0.0958 0.2678
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Onchocerca volvulus Sepiapterin reductase homolog 0.0112 0.0101 0.0506
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0112 0.0101 0.0098
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0048 0.0019 0.0054
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0074 0.0053 0.0275
Leishmania major short chain dehydrogenase, putative 0.0112 0.0101 0.0543
Echinococcus granulosus carbonyl reductase 1 0.0112 0.0101 0.0282
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0054 0.0027 0.0074
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Echinococcus multilocularis conserved hypothetical protein 0.0112 0.0101 0.0282
Trichomonas vaginalis glucosylceramidase, putative 0.0204 0.0219 0.1204
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0054 0.0027 0.0131
Loa Loa (eye worm) hypothetical protein 0.0156 0.0158 0.0206
Onchocerca volvulus 0.1447 0.1807 0.9215
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0107 0.0095 0.0265
Echinococcus granulosus retinol dehydrogenase 11 0.0112 0.0101 0.0282
Echinococcus multilocularis cathepsin b 0.2832 0.3577 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0204 0.0219 0.0286
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0112 0.0101 0.0277
Echinococcus multilocularis transmembrane protease serine 3 0.0059 0.0033 0.0094
Schistosoma mansoni cathepsin D (A01 family) 0.006 0.0034 0.0094
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.033 0.038 0.2089
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0112 0.0101 0.028
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0543
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0806 0.0988 0.2761
Echinococcus multilocularis expressed conserved protein 0.0074 0.0052 0.0146
Leishmania major hypothetical protein, conserved 0.0074 0.0053 0.0275
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0044
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Plasmodium vivax unspecified product 0.033 0.038 0.2089
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.033 0.038 0.106
Echinococcus multilocularis polycomb protein SCMH1 0.0035 0.0002 0.0007
Echinococcus multilocularis geminin 0.0451 0.0535 0.1494
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0035 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0074 0.0053 0.0147
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0053 0.0026 0.0072
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0112 0.0101 0.0282
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0126 0.0118 0.0329
Entamoeba histolytica papain family cysteine protease domain containing protein 0.033 0.038 0.2094
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0037 0.0005 0.0023
Brugia malayi Papain family cysteine protease containing protein 0.033 0.038 0.1062
Echinococcus multilocularis neuropeptides capa receptor 0.0222 0.0242 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0126 0.0118 0.0331
Leishmania major hypothetical protein, conserved 0.0074 0.0053 0.0275
Echinococcus granulosus sterol regulatory element binding protein 0.0034 0.0001 0.0003
Onchocerca volvulus 0.0222 0.0242 0.1228
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Schistosoma mansoni myosin xvIII 0.0222 0.0242 0.0675
Entamoeba histolytica cysteine protease, putative 0.033 0.038 0.2094
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Brugia malayi ADAMTS-like protease 0.0116 0.0106 0.0298
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0112 0.0101 0.0098
Loa Loa (eye worm) hypothetical protein 0.0149 0.0148 0.0194
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0074 0.0053 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.033 0.038 0.2089
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0222 0.0242 0.0677
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0112 0.0101 0.0282
Mycobacterium ulcerans short-chain dehydrogenase 0.0112 0.0101 0.0092
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0107 0.0095 0.0263
Brugia malayi cytochrome P450 0.004 0.0009 0.0025
Trypanosoma brucei oxidoreductase-like protein 0.0112 0.0101 0.0543
Onchocerca volvulus Huntingtin homolog 0.0086 0.0068 0.0339
Schistosoma mansoni smad1 5 8 and 0.0048 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.1695 0.2125 0.2777
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.038 0.2097
Schistosoma mansoni glutaminase 0.0172 0.0178 0.0495
Loa Loa (eye worm) hypothetical protein 0.2817 0.3558 0.4649
Entamoeba histolytica cysteine proteinase, putative 0.0783 0.0958 0.5299
Onchocerca volvulus 0.1447 0.1807 0.9215
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0074 0.0053 0.0286
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0393 0.046 0.2539
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0112 0.0101 0.0277
Loa Loa (eye worm) disintegrin family protein 0.011 0.0099 0.0129
Loa Loa (eye worm) hypothetical protein 0.0648 0.0787 0.1028
Toxoplasma gondii cathepsin B 0.1104 0.1369 0.757
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0393 0.046 0.2539
Schistosoma mansoni sodium/chloride dependent transporter 0.0126 0.0118 0.0329
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0059 0.0033 0.0094
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0065 0.0041 0.0114
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0226 0.0247 0.125
Leishmania major protein kinase A regulatory subunit, putative 0.0074 0.0053 0.0275
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0083 0.0064 0.0177
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0079 0.0221
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0034 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.033 0.038 0.2097
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Loa Loa (eye worm) hypothetical protein 0.0994 0.1228 0.1605
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0165 0.0169 0.0473
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0536 0.0644 0.1799
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0074 0.0053 0.0147
Schistosoma mansoni neuropeptide receptor 0.0222 0.0242 0.0675
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Schistosoma mansoni neuropeptide receptor 0.0301 0.0343 0.0957
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0009 0.0006
Mycobacterium ulcerans glutaminase 0.0172 0.0178 0.0169
Giardia lamblia Cathepsin L-like protease 0.033 0.038 0.2686
Brugia malayi Matrixin family protein 0.0648 0.0787 0.2199
Leishmania major hypothetical protein, conserved 0.0118 0.0109 0.0589
Onchocerca volvulus 0.0074 0.0053 0.026
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0009 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Entamoeba histolytica cysteine protease, putative 0.033 0.038 0.2094
Giardia lamblia Hypothetical protein 0.0054 0.0027 0.0074
Loa Loa (eye worm) hypothetical protein 0.0083 0.0064 0.0084
Schistosoma mansoni cathepsin D (A01 family) 0.006 0.0034 0.0094
Loa Loa (eye worm) hypothetical protein 0.074 0.0903 0.1181
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0009 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0029 0.0145
Loa Loa (eye worm) hypothetical protein 0.033 0.038 0.0496
Schistosoma mansoni Smad4 0.0048 0.0019 0.0052
Echinococcus granulosus TGF beta signal transducer SmadC 0.0048 0.0019 0.0054
Echinococcus multilocularis serotonin receptor 0.0222 0.0242 0.0677
Schistosoma mansoni egf-like domain protein 0.0042 0.0012 0.0032
Brugia malayi Matrixin family protein 0.1599 0.2002 0.5596
Mycobacterium ulcerans hypothetical protein 0.0074 0.0053 0.0044
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0003 0.0008
Mycobacterium ulcerans dehydrogenase 0.0112 0.0101 0.0092
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0033 0.0092
Schistosoma mansoni sodium-dependent amino acid transporter 0.0126 0.0118 0.0329
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0165 0.0169 0.0473
Onchocerca volvulus 0.0112 0.0101 0.0506
Brugia malayi RNA, U transporter 1 0.0061 0.0036 0.0099
Loa Loa (eye worm) hypothetical protein 0.0994 0.1228 0.1605
Echinococcus granulosus cpg binding protein 0.0033 0.0001 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Brugia malayi hypothetical protein 0.0126 0.0118 0.0331
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0112 0.0101 0.0277
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0044
Trichomonas vaginalis set domain proteins, putative 0.0653 0.0793 0.4385
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0053 0.0143
Echinococcus multilocularis histone acetyltransferase MYST2 0.004 0.0009 0.0024
Echinococcus granulosus hypothetical protein 0.0222 0.0242 0.0677
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0272 0.0306 0.0854
Mycobacterium ulcerans carveol-like dehydrogenase 0.0112 0.0101 0.0092
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0112 0.0101 0.0098
Loa Loa (eye worm) hypothetical protein 0.033 0.038 0.0496
Echinococcus granulosus somatostatin receptor 0.0222 0.0242 0.0677
Schistosoma mansoni lipoxygenase 0.0072 0.005 0.0138
Onchocerca volvulus 0.0222 0.0242 0.1228
Entamoeba histolytica hypothetical protein 0.0065 0.0041 0.0216
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0053 0.005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.0331
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0222 0.0242 0.0317
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Mycobacterium ulcerans transmembrane transport protein 0.0074 0.0053 0.0044
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0074 0.0053 0.0147
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0156 0.0158 0.0441
Onchocerca volvulus 0.0112 0.0101 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.033 0.038 0.2097
Entamoeba histolytica cysteine protease, putative 0.033 0.038 0.2094
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Plasmodium falciparum amino acid transporter, putative 0.0126 0.0118 0.064
Treponema pallidum cyclic nucleotide binding protein 0.0074 0.0053 0.0297
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0144 0.0142 0.0396
Plasmodium falciparum cysteine proteinase falcipain 3 0.1447 0.1807 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Onchocerca volvulus 0.0222 0.0242 0.1228
Echinococcus granulosus cathepsin l1 0.1447 0.1807 0.5052
Trypanosoma brucei short-chain dehydrogenase, putative 0.0112 0.0101 0.0543
Schistosoma mansoni aldehyde dehydrogenase 0.0187 0.0198 0.055
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0222 0.0242 0.0317
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.007
Schistosoma mansoni hypothetical protein 0.0822 0.1008 0.2817
Trichomonas vaginalis ras GTP exchange factor, putative 0.0034 0.0002 0.0004
Leishmania major short chain dehydrogenase/reductase, putative 0.0112 0.0101 0.0543
Echinococcus granulosus tm gpcr rhodopsin 0.0222 0.0242 0.0677
Echinococcus granulosus carbonyl reductase 1 0.0112 0.0101 0.0282
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0777 0.0951 0.2659
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0074 0.0053 0.005
Loa Loa (eye worm) MH2 domain-containing protein 0.0704 0.0858 0.112
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.006 0.0034 0.0305
Onchocerca volvulus 0.0054 0.0027 0.0127
Brugia malayi Calcitonin receptor-like protein seb-1 0.1695 0.2125 0.5941
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0074 0.0053 0.0275
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0034 0.0002 0.0005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0222 0.0242 0.0675
Leishmania major DNA polymerase eta, putative 0.0043 0.0013 0.0056
Brugia malayi Cathepsin L-like precursor 0.1447 0.1807 0.5052
Schistosoma mansoni sex comb on midleg homolog 0.0035 0.0002 0.0005
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0086 0.0067 0.0187
Schistosoma mansoni neuropeptide F-like receptor 0.0222 0.0242 0.0675
Schistosoma mansoni dep domain containing protein 0.0048 0.0019 0.0052
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1104 0.1369 0.3823
Echinococcus multilocularis GPCR, family 2 0.0536 0.0644 0.1799
Mycobacterium tuberculosis Possible oxidoreductase 0.0112 0.0101 0.0098
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Echinococcus multilocularis transient receptor potential cation channel 0.0112 0.0101 0.0282
Loa Loa (eye worm) glutaminase 0.0172 0.0178 0.0232
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0053 0.0275
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0112 0.0101 0.0277
Schistosoma mansoni tar DNA-binding protein 0.0864 0.1062 0.2968
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0222 0.0242 0.0675
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0429 0.0506 0.1416
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0074 0.0053 0.0275
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Echinococcus granulosus segment polarity protein dishevelled 0.0048 0.0019 0.0054
Giardia lamblia Cathepsin B precursor 0.033 0.038 0.2686
Trypanosoma cruzi cysteine proteinase, putative 0.0783 0.0958 0.2676
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0112 0.0101 0.0277
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Trichomonas vaginalis ras GTP exchange factor, putative 0.0034 0.0002 0.0004
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0112 0.0101 0.0098
Loa Loa (eye worm) hypothetical protein 0.1447 0.1807 0.2361
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.033 0.038 0.2097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.038 0.2097
Trypanosoma brucei hypothetical protein, conserved 0.0054 0.0027 0.0131
Schistosoma mansoni biogenic amine receptor 0.0222 0.0242 0.0675
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.039 0.0457 0.0448
Brugia malayi Cytochrome P450 family protein 0.0046 0.0017 0.0049
Echinococcus multilocularis protein patched 0.0034 0.0001 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0017 0.0023
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0048 0.0019 0.0025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0013 0.001
Brugia malayi Dopamine receptor protein 2 0.0222 0.0242 0.0677
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0112 0.0101 0.0549
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0204 0.0219 0.1204
Brugia malayi Cytochrome P450 family protein 0.0046 0.0017 0.0049
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0095 0.0263
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0009 0.0006
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1104 0.1369 0.757
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Trichomonas vaginalis fk506 binding protein, putative 0.0054 0.0027 0.0142
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0074 0.0053 0.0145
Mycobacterium ulcerans short-chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0194 0.0206 0.0203
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0074 0.0053 0.0145
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Schistosoma mansoni cathepsin F (C01 family) 0.1447 0.1807 0.5051
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Leishmania major peptidylprolyl isomerase-like protein 0.039 0.0457 0.2516
Echinococcus granulosus geminin 0.0451 0.0535 0.1494
Onchocerca volvulus 0.0112 0.0101 0.0506
Loa Loa (eye worm) norepinephrine transporter 0.074 0.0903 0.1181
Brugia malayi RE15519p 0.0222 0.0242 0.0677
Brugia malayi Cathepsin L-like precursor 0.1447 0.1807 0.5052
Leishmania major protein kinase, putative 0.0074 0.0053 0.0275
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Trypanosoma brucei Flagellar Member 6 0.0074 0.0053 0.0275
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0091 0.0074 0.0206
Trypanosoma brucei cAMP response protein 1, putative 0.0074 0.0053 0.0275
Brugia malayi ADAM-TS Spacer 1 family protein 0.0116 0.0106 0.0298
Echinococcus multilocularis sodium and chloride dependent glycine 0.0126 0.0118 0.0331
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0034 0.0002 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Schistosoma mansoni smad1 5 8 and 0.0048 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0994 0.1228 0.1605
Onchocerca volvulus 0.0112 0.0101 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0083 0.0064 0.0179
Brugia malayi Cathepsin L-like precursor 0.1447 0.1807 0.5052
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0864 0.1062 0.1388
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.0783 0.0958 0.5299
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.0013 0.0037
Leishmania major regulatory subunit of protein kinase a-like protein 0.0074 0.0053 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0101 0.0277
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0034 0.0002 0.0003
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0048 0.0019 0.0052
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0453 0.0537 0.15
Echinococcus multilocularis steroid dehydrogenase 0.0112 0.0101 0.0282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2832 0.3577 1
Giardia lamblia Cathepsin L-like protease 0.033 0.038 0.2686
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0222 0.0242 0.0677
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0037 0.0005 0.0012
Entamoeba histolytica cysteine protease, putative 0.033 0.038 0.2094
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0074 0.0053 0.0267
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0114 0.0313
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0137 0.0133 0.0372
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0112 0.0101 0.0092
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0062 0.0038 0.0192
Schistosoma mansoni myelin transcription factor 1 myt1 0.004 0.0009 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Brugia malayi Niemann-Pick C1 protein precursor 0.0079 0.0058 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0222 0.0242 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0074 0.0053 0.0145
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.033 0.038 0.106
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0029 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Schistosoma mansoni sodium/chloride dependent transporter 0.0126 0.0118 0.0329
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.0331
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Leishmania major hypothetical protein, conserved 0.0122 0.0114 0.0613
Mycobacterium ulcerans hypothetical protein 0.0074 0.0053 0.0044
Loa Loa (eye worm) TYRA-2 protein 0.0222 0.0242 0.0317
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0112 0.0101 0.0543
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0806 0.0988 0.2762
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0074 0.0053 0.0275
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.1029 0.1273 0.6489
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0074 0.0053 0.0143
Loa Loa (eye worm) cytochrome P450 0.004 0.0009 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0009 0.0006
Mycobacterium ulcerans hypothetical protein 0.0054 0.0027 0.0018
Giardia lamblia Cathepsin L precursor 0.033 0.038 0.2686
Plasmodium vivax SET domain protein, putative 0.0083 0.0064 0.0338
Echinococcus granulosus peptidase Clp S14 family 0.0041 0.001 0.0029
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Plasmodium vivax serine-repeat antigen (SERA), putative 0.033 0.038 0.2089
Echinococcus multilocularis adam 0.0272 0.0306 0.0856
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0074 0.0053 0.0147
Echinococcus granulosus son of sevenless 1 0.0034 0.0002 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0033 0.0092
Brugia malayi ORL1-like opioid receptor 0.0222 0.0242 0.0677
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0107 0.0095 0.0265
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0009 0.0034
Loa Loa (eye worm) trypsin family protein 0.0059 0.0033 0.0044
Brugia malayi Cyclic-nucleotide gated cation channel 0.0107 0.0095 0.0265
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0054 0.0027 0.0075
Brugia malayi Dehydrogenases, short chain protein 2 0.0112 0.0101 0.0282
Echinococcus multilocularis son of sevenless 1 0.0034 0.0002 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.0222 0.0242 0.0677
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0009 0.0021
Giardia lamblia Cathepsin B precursor 0.033 0.038 0.2686
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0034 0.0002 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Onchocerca volvulus 0.0083 0.0064 0.0318
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0396 0.0465 0.2566
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.1491
Entamoeba histolytica cysteine proteinase 2 0.0783 0.0958 0.5299
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0054 0.0027 0.0131
Loa Loa (eye worm) hypothetical protein 0.0034 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0037 0.0005 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.1447 0.1807 0.5049
Loa Loa (eye worm) hypothetical protein 0.0079 0.0058 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.074 0.0903 0.2526
Echinococcus granulosus histone lysine methyltransferase setb 0.0083 0.0064 0.0179
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0128 0.0122 0.034
Leishmania major hypothetical protein, conserved 0.0112 0.0101 0.0543
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0112 0.0101 0.0553
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0187 0.0198 0.0195
Trypanosoma cruzi major cysteine proteinase, putative 0.033 0.038 0.1057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Loa Loa (eye worm) papain family cysteine protease containing protein 0.033 0.038 0.0496
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.079 0.0967 0.0965
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1447 0.1807 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0429 0.0506 0.0662
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0112 0.0101 0.0543
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0112 0.0101 0.0277
Echinococcus granulosus cGMP dependent protein kinase 1 0.0074 0.0053 0.0147
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0112 0.0101 0.0098
Loa Loa (eye worm) transcription factor SMAD2 0.0704 0.0858 0.112
Loa Loa (eye worm) hypothetical protein 0.0074 0.0053 0.0069
Loa Loa (eye worm) isocitrate dehydrogenase 0.0035 0.0003 0.0004
Echinococcus granulosus serotonin receptor 0.0222 0.0242 0.0677
Trypanosoma cruzi cysteine peptidase, putative 0.1447 0.1807 0.5049
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0112 0.0101 0.028
Leishmania major hypothetical protein, conserved 0.0112 0.0101 0.0543
Echinococcus granulosus cathepsin L 0.0783 0.0958 0.2679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0536 0.0644 0.1799
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Entamoeba histolytica short chain dehydrogenase family protein 0.0112 0.0101 0.0549
Brugia malayi Dehydrogenases, short chain protein 30 0.0112 0.0101 0.0282
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0112 0.0101 0.0277
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0009 0.0034
Echinococcus multilocularis neuropeptide receptor 0.0222 0.0242 0.0677
Leishmania major quinonoid dihydropteridine reductase 0.0112 0.0101 0.0543
Schistosoma mansoni 60S ribosomal protein L21 0.007 0.0047 0.013
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0009 0.0006
Brugia malayi hypothetical protein 0.0086 0.0068 0.0191
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0112 0.0101 0.0277
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.039 0.0457 0.2524
Echinococcus granulosus snurportin 1 0.0228 0.0249 0.0697
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0054 0.0027 0.0074
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0112 0.0101 0.0553
Leishmania major hypothetical protein, conserved 0.0112 0.0101 0.0543
Mycobacterium ulcerans hypothetical protein 0.0074 0.0053 0.0044
Echinococcus granulosus Protein patched homolog 1 0.0034 0.0001 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus granulosus cysteine protease 0.0783 0.0958 0.2679
Schistosoma mansoni cathepsin S (C01 family) 0.033 0.038 0.106
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0027 0.0135
Mycobacterium ulcerans short-chain dehydrogenase 0.0112 0.0101 0.0092
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Echinococcus multilocularis neuropeptide Y receptor 0.0222 0.0242 0.0677
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.079 0.0967 0.2704
Trypanosoma cruzi cysteine peptidase, putative 0.0453 0.0537 0.1496
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0112 0.0101 0.0996
Trypanosoma brucei short-chain dehydrogenase, putative 0.0112 0.0101 0.0543
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Trypanosoma cruzi PAB1-binding protein , putative 0.0118 0.0109 0.0301
Echinococcus multilocularis G-protein coupled receptor, putative 0.0222 0.0242 0.0677
Loa Loa (eye worm) hypothetical protein 0.0116 0.0106 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Schistosoma mansoni hypothetical protein 0.0037 0.0005 0.0012
Echinococcus multilocularis Tolloid protein 1 0.0042 0.0012 0.0034
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0032 0.0091
Brugia malayi G protein-coupled receptor F59B2.13 0.0222 0.0242 0.0677
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0054 0.0027 0.0035
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0222 0.0242 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.038 0.2097
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0994 0.1228 0.6796
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0144 0.0142 0.0396
Brugia malayi Protein kinase domain containing protein 0.0122 0.0114 0.0318
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0079 0.0219
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0053 0.005
Brugia malayi Serotonin receptor 0.0222 0.0242 0.0677
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Schistosoma mansoni hypothetical protein 0.0059 0.0033 0.0092
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.0192
Echinococcus granulosus dro:myosuppressin receptor 0.0222 0.0242 0.0677
Loa Loa (eye worm) hypothetical protein 0.004 0.0009 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.0101 0.0098
Echinococcus multilocularis Protein son of sevenless 0.0034 0.0002 0.0005
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0112 0.0101 0.0098
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus granulosus regulator of G protein signaling 7 0.0048 0.0019 0.0054
Trypanosoma cruzi cAMP binding protein, putative 0.0074 0.0053 0.0143
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Leishmania major hypothetical protein, conserved 0.0112 0.0101 0.0543
Echinococcus granulosus tissue type plasminogen activator 0.0122 0.0114 0.0318
Loa Loa (eye worm) reprolysin 0.0156 0.0158 0.0206
Echinococcus multilocularis carbonyl reductase 1 0.0112 0.0101 0.0282
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Schistosoma mansoni cytochrome P450 0.004 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0059 0.0033 0.0044
Onchocerca volvulus 0.0059 0.0033 0.0162
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Brugia malayi cahepsin L-like non-peptiedase homolog 0.033 0.038 0.1062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.038 0.2097
Entamoeba histolytica hypothetical protein, conserved 0.0112 0.0101 0.0549
Echinococcus granulosus regulator of G protein signaling 7 0.0048 0.0019 0.0054
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0543
Leishmania major dehydrogenase-like protein 0.0112 0.0101 0.0543
Treponema pallidum catabolite gene activator 0.0077 0.0056 0.0332
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0009 0.0006
Onchocerca volvulus Matrilysin homolog 0.0648 0.0787 0.4007
Loa Loa (eye worm) hypothetical protein 0.0551 0.0662 0.0865
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0423 0.0498 0.1392
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0035 0.0002 0.0004
Schistosoma mansoni hypothetical protein 0.0228 0.0249 0.0695
Toxoplasma gondii cathepsin CPC1 0.033 0.038 0.2089
Entamoeba histolytica papain family cysteine protease domain containing protein 0.033 0.038 0.2094
Leishmania major pteridine reductase 1 0.0112 0.0101 0.0543
Giardia lamblia Cathepsin B precursor 0.033 0.038 0.2686
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0783 0.0958 0.2678
Loa Loa (eye worm) hypothetical protein 0.0551 0.0662 0.0865
Brugia malayi MH2 domain containing protein 0.0048 0.0019 0.0054
Echinococcus granulosus cathepsin l1 0.0994 0.1228 0.3434
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.0131
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0079 0.0221
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0074 0.0053 0.2837
Brugia malayi TAR-binding protein 0.0864 0.1062 0.2969
Loa Loa (eye worm) hypothetical protein 0.0126 0.0118 0.0155
Schistosoma mansoni opsin-like receptor 0.0222 0.0242 0.0675
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0112 0.0101 0.0277
Schistosoma mansoni carbonyl reductase 0.0112 0.0101 0.028
Onchocerca volvulus 0.0222 0.0242 0.1228
Echinococcus multilocularis expressed conserved protein 0.0074 0.0053 0.0147
Leishmania major hypothetical protein, unknown function 0.0074 0.0053 0.0275
Giardia lamblia Cathepsin B precursor 0.1104 0.1369 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0035 0.0003 0.0008
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.1116 0.1385 0.3872
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.033 0.038 0.0496
Echinococcus multilocularis g-protein coupled receptor 0.0222 0.0242 0.0677
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0079 0.0221
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Toxoplasma gondii hypothetical protein 0.0126 0.0118 0.064
Loa Loa (eye worm) papain family cysteine protease containing protein 0.033 0.038 0.0496
Onchocerca volvulus 0.0112 0.0101 0.0506
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0034 0.0002 0.0005
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0156 0.0158 0.0441
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0365 0.0425 0.1188
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0055 0.0029 0.0143
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0128 0.0122 0.0335
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.038 0.2097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Echinococcus granulosus inositol monophosphatase 1 0.0055 0.0029 0.0081
Brugia malayi MH2 domain containing protein 0.0704 0.0858 0.2397
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1185 0.1472 0.1924
Brugia malayi MH1 domain containing protein 0.0048 0.0019 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0222 0.0242 0.0675
Echinococcus multilocularis cathepsin L cysteine protease 0.1447 0.1807 0.5052
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0046 0.0017 0.0014
Giardia lamblia Dipeptidyl-peptidase I precursor 0.033 0.038 0.2686
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.0101 0.0098
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0083 0.0064 0.0179
Trichomonas vaginalis immunophilin, putative 0.039 0.0457 0.2524
Trypanosoma cruzi major cysteine proteinase, putative 0.033 0.038 0.1057
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0126 0.0118 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0068 0.0089
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0037 0.0005 0.0023
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0128 0.0122 0.0335
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0107 0.0095 0.0265
Onchocerca volvulus 0.0048 0.0019 0.009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Echinococcus granulosus neuropeptide receptor A26 0.0778 0.0952 0.2662
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Brugia malayi Inositol-1 0.0055 0.0029 0.0081
Brugia malayi N-terminal motif family protein 0.1029 0.1273 0.3559
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Brugia malayi Papain family cysteine protease containing protein 0.0783 0.0958 0.2679
Schistosoma mansoni short chain dehydrogenase 0.0112 0.0101 0.028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0048 0.0131
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0033 0.0092
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0122 0.0115 0.0625
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.038 0.2097
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0034 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Mycobacterium ulcerans short-chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus multilocularis retinol dehydrogenase 11 0.0112 0.0101 0.0282
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0074 0.0053 0.0145
Brugia malayi Retinol dehydrogenase 12 0.0112 0.0101 0.0282
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.005 0.0021 0.0018
Schistosoma mansoni hypothetical protein 0.045 0.0533 0.149
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Loa Loa (eye worm) fibroinase 0.1447 0.1807 0.2361
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.033 0.038 0.106
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0053 0.0026 0.0072
Brugia malayi oxidoreductase 0.0112 0.0101 0.0282
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Onchocerca volvulus 0.0058 0.0032 0.0157
Plasmodium falciparum transporter, putative 0.0126 0.0118 0.064
Echinococcus granulosus segment polarity protein dishevelled 0.0048 0.0019 0.0054
Brugia malayi RasGEF domain containing protein 0.0034 0.0002 0.0005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.064
Loa Loa (eye worm) hypothetical protein 0.6021 0.7653 1
Giardia lamblia Cathepsin B precursor 0.033 0.038 0.2686
Onchocerca volvulus 0.0222 0.0242 0.1228
Plasmodium vivax amine transporter, putative 0.0126 0.0118 0.064
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0137 0.0133 0.0372
Loa Loa (eye worm) hypothetical protein 0.0042 0.0012 0.0016
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0017 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.0198 0.0189
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0027 0.0135
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0046 0.0017 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0994 0.1228 0.6796
Onchocerca volvulus Cathepsin F homolog 0.1447 0.1807 0.9215
Loa Loa (eye worm) neuropeptide F receptor 0.0222 0.0242 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1447 0.1807 1
Echinococcus granulosus cGMP dependent protein kinase 0.0074 0.0053 0.0147
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.039 0.0457 0.1273
Brugia malayi prolyl oligopeptidase family protein 0.0226 0.0247 0.069
Schistosoma mansoni amine GPCR 0.0222 0.0242 0.0675
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0783 0.0958 0.5296
Mycobacterium ulcerans aldehyde dehydrogenase 0.0187 0.0198 0.0189
Brugia malayi hypothetical protein 0.0272 0.0306 0.0856
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0187 0.0198 0.0552
Loa Loa (eye worm) hypothetical protein 0.0042 0.0012 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Echinococcus granulosus g protein coupled receptor 0.0222 0.0242 0.0677
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0037 0.0005 0.0023
Trichomonas vaginalis fk506-binding protein, putative 0.0054 0.0027 0.0142
Echinococcus granulosus g protein coupled receptor 0.0222 0.0242 0.0677
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0056 0.003 0.0083
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0112 0.0101 0.0277
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0864 0.1062 0.2968
Schistosoma mansoni dihydroceramide desaturase 0.0266 0.0298 0.0832
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0074 0.0053 0.005
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0226 0.0247 0.069
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.039 0.0457 0.4908
Echinococcus granulosus g-protein coupled receptor 0.0222 0.0242 0.0677
Schistosoma mansoni adenoreceptor 0.0222 0.0242 0.0675
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0059 0.0033 0.0094
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0423 0.0498 0.1392
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0226 0.0247 0.0688
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.0323 0.0903
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0037 0.0005 0.0014
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0126 0.0118 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0222 0.0242 0.0677
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0187 0.0198 0.0552
Treponema pallidum catabolite gene activator (Crp) 0.0074 0.0053 0.0297
Brugia malayi hypothetical protein 0.0286 0.0323 0.0903
Giardia lamblia Cysteine protease 0.033 0.038 0.2686
Onchocerca volvulus 0.0126 0.0118 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.033 0.038 0.2097
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.0131
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0013 0.0037
Echinococcus granulosus tachykinin peptides receptor 99D 0.0365 0.0425 0.1188
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0037 0.0005 0.0023
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0072 0.005 0.014
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0188 0.0199 0.1346
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) dehydrogenase 0.0112 0.0101 0.0132
Schistosoma mansoni biogenic amine (5HT) receptor 0.0222 0.0242 0.0675
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0054 0.0027 0.0074
Brugia malayi cathepsin F-like cysteine proteinase 0.033 0.038 0.1062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Schistosoma mansoni hypothetical protein 0.0058 0.0032 0.0089
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0074 0.0053 0.0147
Schistosoma mansoni hypothetical protein 0.0222 0.0242 0.0675
Echinococcus granulosus tm gpcr rhodopsin 0.0222 0.0242 0.0677
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0112 0.0101 0.0277
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Leishmania major hypothetical protein, conserved 0.0074 0.0053 0.0275
Echinococcus granulosus Protein son of sevenless 0.0034 0.0002 0.0005
Loa Loa (eye worm) melatonin receptor type 1A 0.0222 0.0242 0.0317
Echinococcus granulosus sex peptide receptor 0.0222 0.0242 0.0677
Plasmodium vivax vivapain-3 0.0783 0.0958 0.5296
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0079 0.0221
Echinococcus granulosus adam 17 protease 0.1863 0.2339 0.6539
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0222 0.0242 0.0675
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0017 0.0008
Brugia malayi Hemopexin family protein 0.0822 0.1008 0.2819
Loa Loa (eye worm) hypothetical protein 0.0777 0.0951 0.1243
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0054 0.0027 0.0131
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0029 0.0076
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0126 0.0118 0.0329
Schistosoma mansoni dishevelled 0.0048 0.0019 0.0052
Brugia malayi Kringle domain containing protein 0.0122 0.0114 0.0318
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.033 0.038 0.2089
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0035 0.0003 0.0004
Schistosoma mansoni aldehyde dehydrogenase 0.0187 0.0198 0.055
Trypanosoma cruzi Flagellar Member 6 0.0074 0.0053 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0009 0.0006
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0112 0.0101 0.0098
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0041 0.001 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Echinococcus multilocularis G protein coupled receptor 139 0.0301 0.0343 0.0959
Schistosoma mansoni fk506 binding protein 0.0054 0.0027 0.0073
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0027 0.0072
Treponema pallidum fructose-bisphosphate aldolase 0.0122 0.0115 0.1002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0107 0.0095 0.0518
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.039 0.0457 0.1277
Brugia malayi Cytochrome P450 family protein 0.004 0.0009 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0134 0.0129 0.0708
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.039 0.0457 0.0597
Treponema pallidum sodium- and chloride- dependent transporter 0.074 0.0903 1
Mycobacterium ulcerans short chain dehydrogenase 0.0112 0.0101 0.0092
Echinococcus multilocularis cathepsin L 0.0783 0.0958 0.2679
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2832 0.3577 1
Entamoeba histolytica hypothetical protein 0.033 0.038 0.2094
Echinococcus multilocularis 0.004 0.0009 0.0025
Echinococcus granulosus biogenic amine 5HT receptor 0.0222 0.0242 0.0677
Onchocerca volvulus 0.0994 0.1228 0.6261
Trichomonas vaginalis adenylate cyclase type, putative 0.0037 0.0005 0.0023
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0112 0.0101 0.0543
Loa Loa (eye worm) oxidoreductase 0.0112 0.0101 0.0132
Schistosoma mansoni transcription factor LCR-F1 0.0065 0.0041 0.0112
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0062 0.0038 0.1206
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0112 0.0101 0.0282
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0222 0.0242 0.0677
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0033 0.0094
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Schistosoma mansoni inositol monophosphatase 0.0055 0.0029 0.0079
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0112 0.0101 0.0092
Toxoplasma gondii cathepsin CPL 0.1447 0.1807 1
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0222 0.0242 0.0677
Plasmodium falciparum serine repeat antigen 2 0.033 0.038 0.2089
Brugia malayi cathepsin F-like cysteine proteinase 0.0453 0.0537 0.15
Trypanosoma cruzi cAMP response protein 1 0.0074 0.0053 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Onchocerca volvulus Matrilysin homolog 0.1567 0.1961 1
Entamoeba histolytica cysteine protease, putative 0.033 0.038 0.2094
Schistosoma mansoni neuropeptide F-like receptor 0.0222 0.0242 0.0675
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0054 0.0027 0.0131
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.0013 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0222 0.0242 0.0675
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0055 0.0029 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.033 0.038 0.2097
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0864 0.1062 0.2968
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0059 0.0033 0.0094
Plasmodium falciparum steroid dehydrogenase, putative 0.0112 0.0101 0.0543
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0074 0.0053 0.0145
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0054 0.0027 0.007
Echinococcus granulosus retinol dehydrogenase 11 0.0112 0.0101 0.0282
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0222 0.0242 0.0675
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0112 0.0101 0.0543
Loa Loa (eye worm) hypothetical protein 0.033 0.038 0.0496
Loa Loa (eye worm) hypothetical protein 0.0648 0.0787 0.1028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0013 0.0037
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0107 0.0095 0.0124
Toxoplasma gondii carbonyl reductase 1, putative 0.0112 0.0101 0.0543
Brugia malayi cathepsin L precursor 0.033 0.038 0.1062
Loa Loa (eye worm) hypothetical protein 0.0453 0.0537 0.0701
Brugia malayi sulfakinin receptor protein 0.0222 0.0242 0.0677
Schistosoma mansoni sodium/chloride dependent transporter 0.074 0.0903 0.2524
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0126 0.0118 0.0331
Onchocerca volvulus 0.0822 0.1008 0.5138
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Toxoplasma gondii cathepsin CPC2 0.033 0.038 0.2089
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0054 0.0027 0.0075
Schistosoma mansoni alpha-1 adrenergic receptor 0.0222 0.0242 0.0675
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.0994 0.1228 0.6795
Onchocerca volvulus 0.0112 0.0101 0.0506
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0035 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0042 0.0012 0.0016
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0074 0.0053 0.0275
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0027 0.0072
Brugia malayi Disintegrin family protein 0.0266 0.0298 0.0834
Trypanosoma brucei short-chain dehydrogenase, putative 0.0112 0.0101 0.0543
Onchocerca volvulus 0.1447 0.1807 0.9215
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0074 0.0053 0.0147
Brugia malayi Cathepsin L-like precursor 0.0453 0.0537 0.15
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0003 0.0008
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0107 0.0095 0.0265
Loa Loa (eye worm) hypothetical protein 0.0034 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.074 0.0903 0.2524
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.005 0.0021 0.0169
Brugia malayi prolyl oligopeptidase family protein 0.0128 0.0122 0.034
Onchocerca volvulus 0.0112 0.0101 0.0506
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0027 0.0072
Schistosoma mansoni inositol monophosphatase 0.0055 0.0029 0.0079
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0013 0.0032
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.0323 0.0903
Plasmodium falciparum cysteine repeat modular protein 1 0.0122 0.0114 0.0613
Loa Loa (eye worm) DIX domain-containing protein 0.0048 0.0019 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Onchocerca volvulus 0.0222 0.0242 0.1228
Brugia malayi larval opioid receptor 0.0222 0.0242 0.0677
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0079 0.0058 0.0314
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.004 0.0009 0.0024
Brugia malayi RasGEF domain containing protein 0.0034 0.0002 0.0005
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0074 0.0053 0.0147
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.0101 0.0098
Entamoeba histolytica cysteine proteinase, putative 0.0783 0.0958 0.5299
Loa Loa (eye worm) hypothetical protein 0.0112 0.0101 0.0132
Plasmodium falciparum ataxin-2 like protein, putative 0.0118 0.0109 0.0589
Loa Loa (eye worm) hypothetical protein 0.0042 0.0012 0.0016
Mycobacterium ulcerans short chain dehydrogenase 0.7857 1 1
Schistosoma mansoni sex comb on midleg homolog 0.0035 0.0002 0.0005
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.039 0.0457 0.3257
Echinococcus granulosus 7TM GPCR rhodopsin 0.0222 0.0242 0.0677
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus granulosus sodium channel protein 0.0091 0.0074 0.0206
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0009 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0122 0.0115 0.0628
Echinococcus multilocularis serotonin receptor 0.0222 0.0242 0.0677
Echinococcus multilocularis sodium and chloride dependent glycine 0.0126 0.0118 0.0331
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0013 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0005 0.0023
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0062 0.0038 0.0105
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.033 0.038 0.106
Schistosoma mansoni peptidase Clp (S14 family) 0.0062 0.0038 0.0104
Onchocerca volvulus 0.074 0.0903 0.4603
Echinococcus multilocularis hyperpolarization activated cyclic 0.0107 0.0095 0.0265
Schistosoma mansoni hypothetical protein 0.0059 0.0033 0.0092
Onchocerca volvulus Huntingtin homolog 0.0086 0.0068 0.0339
Echinococcus multilocularis dna polymerase kappa 0.0054 0.0027 0.0076
Onchocerca volvulus 0.0222 0.0242 0.1228
Giardia lamblia Cathepsin B precursor 0.1104 0.1369 1
Onchocerca volvulus 0.0648 0.0787 0.4007
Loa Loa (eye worm) hypothetical protein 0.1029 0.1273 0.1663
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0074 0.0053 0.0275
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0112 0.0101 0.0132
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0017 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0092
Loa Loa (eye worm) hypothetical protein 0.0222 0.0242 0.0317
Echinococcus granulosus rhodopsin orphan GPCR 0.0222 0.0242 0.0677
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0222 0.0242 0.0677
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023
Brugia malayi hypothetical protein 0.0222 0.0242 0.0677
Loa Loa (eye worm) matrixin family protein 0.1599 0.2002 0.2616
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.0101 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0053 0.0145
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0112 0.0101 0.0549
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0048 0.0019 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0138 0.0759
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.0101 0.0098
Trichomonas vaginalis guanylate cyclase, putative 0.0037 0.0005 0.0023
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0062 0.0038 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0783 0.0958 0.5301
Plasmodium vivax ataxin-2 like protein, putative 0.0118 0.0109 0.0589
Echinococcus multilocularis retinol dehydrogenase 11 0.0112 0.0101 0.0282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.033 0.038 0.106
Schistosoma mansoni voltage-gated potassium channel 0.0144 0.0142 0.0395
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0222 0.0242 0.0675
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0188 0.0199 0.0555
Onchocerca volvulus 0.0551 0.0662 0.337
Schistosoma mansoni amine GPCR 0.0222 0.0242 0.0675
Plasmodium falciparum serine repeat antigen 5 0.033 0.038 0.2089
Leishmania major short chain dehydrogenase-like protein 0.0112 0.0101 0.0543
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0536 0.0644 0.1799
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0339 0.0391 0.1094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0083 0.0064 0.0177
Schistosoma mansoni hypothetical protein 0.0451 0.0535 0.1493
Echinococcus multilocularis dna polymerase eta 0.0043 0.0013 0.0037
Schistosoma mansoni cathepsin F (C01 family) 0.1447 0.1807 0.5051
Echinococcus multilocularis laminin 0.0042 0.0012 0.0034
Echinococcus granulosus sodium and chloride dependent glycine 0.0126 0.0118 0.0331
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0574 0.0692 0.0904
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0222 0.0242 0.0677
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0107 0.0095 0.0263
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0112 0.0101 0.0282
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.004 0.0009 0.0024
Schistosoma mansoni steroid dehydrogenase 0.0112 0.0101 0.028
Brugia malayi Cathepsin L-like precursor 0.1447 0.1807 0.5052
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0025
Leishmania major cathepsin L-like protease 0.1447 0.1807 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.1447 0.1807 0.5052
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0222 0.0242 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1447 0.1807 1
Toxoplasma gondii hypothetical protein 0.0048 0.0019 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1447 0.1807 1
Brugia malayi RNA recognition motif domain containing protein 0.0864 0.1062 0.2969
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0053 0.0286
Leishmania major hypothetical protein, conserved 0.0112 0.0101 0.0543
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0783 0.0958 0.5296
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0037 0.0005 0.0023
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0551 0.0662 0.1849
Leishmania major oxidoreductase-like protein 0.0112 0.0101 0.0543
Echinococcus granulosus dna polymerase eta 0.0043 0.0013 0.0037
Echinococcus multilocularis neuropeptides capa receptor 0.0222 0.0242 0.0677
Loa Loa (eye worm) hypothetical protein 0.0035 0.0002 0.0003
Schistosoma mansoni regulator of G protein signaling 0.0048 0.0019 0.0052
Giardia lamblia Cysteine protease 0.033 0.038 0.2686
Entamoeba histolytica cysteine protease, putative 0.0783 0.0958 0.5299
Brugia malayi follicle stimulating hormone receptor 0.1185 0.1472 0.4116
Echinococcus multilocularis neuropeptide Y receptor 0.0222 0.0242 0.0677
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.1116 0.1385 0.3872
Trichomonas vaginalis hypothetical protein 0.0037 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0286 0.0323 0.0422
Brugia malayi hypothetical protein 0.0048 0.0019 0.0054
Echinococcus multilocularis cathepsin b 0.2832 0.3577 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1447 0.1807 1
Loa Loa (eye worm) ctsf protein 0.1447 0.1807 0.2361
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0112 0.0101 0.0277
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0126 0.0118 0.064
Trichomonas vaginalis adenylate cyclase, putative 0.0037 0.0005 0.0023

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.8526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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