Detailed information for compound 206130

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 264.317 | Formula: C15H20O4
  • H donors: 3 H acceptors: 4 LogP: 0.12 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@]1(C)C=C2C(=C(C)C3([C@@](C2=O)(C)O)CC3)C1O
  • InChi: 1S/C15H20O4/c1-8-10-9(6-13(2,7-16)12(10)18)11(17)14(3,19)15(8)4-5-15/h6,12,16,18-19H,4-5,7H2,1-3H3/t12?,13-,14-/m0/s1
  • InChiKey: DDLLIYKVDWPHJI-TTZKSVMKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni lipoxygenase 0.1345 0.2087 0.2086
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Onchocerca volvulus 0.0052 0.0025 0.0034
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0163 0.0202 0.0251
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0122 0.0137 0.0233
Entamoeba histolytica hypothetical protein 0.0103 0.0106 0.0128
Brugia malayi AF-10 protein 0.0087 0.0081 0.0126
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0122 0.0137 0.0335
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0051 0.0024 0.0057
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0072 0.0057 0.0056
Schistosoma mansoni chromodomain helicase DNA binding protein 0.015 0.0181 0.018
Echinococcus multilocularis carbonyl reductase 1 0.0122 0.0137 0.0137
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0163 0.0202 0.0314
Treponema pallidum oxidoreductase 0.0094 0.0092 0.0086
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0206
Leishmania major cysteine peptidase A (CPA) 0.0069 0.0052 0.0088
Brugia malayi Importin beta-1 subunit 0.009 0.0085 0.0132
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.2481 0.3898 0.9553
Echinococcus granulosus glutamate synthase 0.0094 0.0092 0.0092
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0094 0.0092 0.0236
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0019 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0928 0.1422 0.3647
Echinococcus multilocularis jumonji domain containing protein 0.0372 0.0535 0.0535
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0102 0.0105 0.0104
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0355 0.0508 0.3223
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0122 0.0137 0.0137
Loa Loa (eye worm) thioredoxin reductase 0.1023 0.1574 0.2454
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0051 0.0024 0.0039
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0038 0.0003 0.0003
Echinococcus granulosus phd:f box containing protein 0.0117 0.0129 0.0129
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0122 0.0137 0.0335
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0051 0.0024 0.0057
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0045 0.007
Loa Loa (eye worm) hypothetical protein 0.0091 0.0087 0.0135
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0142 0.0168 0.0262
Mycobacterium ulcerans acyl-CoA synthetase 0.0218 0.029 0.0742
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0051 0.0024 0.0036
Schistosoma mansoni notch 0.0052 0.0025 0.0025
Loa Loa (eye worm) notch protein 0.0052 0.0025 0.0039
Echinococcus multilocularis cathepsin L cysteine protease 0.0069 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0094 0.0092 0.0225
Echinococcus granulosus RUN 0.0582 0.0869 0.0869
Onchocerca volvulus 0.0122 0.0137 0.0187
Onchocerca volvulus Huntingtin homolog 0.0132 0.0153 0.0209
Trichomonas vaginalis hypothetical protein 0.015 0.0181 0.0224
Mycobacterium ulcerans glutamate synthase subunit beta 0.0094 0.0092 0.0236
Loa Loa (eye worm) hypothetical protein 0.0117 0.0129 0.0201
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Schistosoma mansoni amyloid beta A4 protein related 0.0276 0.0382 0.0381
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0122 0.0137 0.0351
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0137 0.0233
Brugia malayi beta-lactamase family protein 0.029 0.0404 0.063
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0274
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0067 0.0049 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0188 0.0459
Loa Loa (eye worm) fibroinase 0.0069 0.0052 0.0081
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0094 0.0092 0.0157
Brugia malayi Associated with TFs and helicases family protein 0.015 0.0181 0.0281
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0044 0.0068
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.015 0.0181 0.0181
Brugia malayi orphan nuclear receptor NR2E1 0.0048 0.0019 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0163 0.0202 0.0251
Leishmania major short chain dehydrogenase/reductase, putative 0.0122 0.0137 0.0233
Echinococcus multilocularis thyroid hormone receptor alpha 0.0102 0.0105 0.0105
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0127 0.0144 0.0369
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0583 0.0872 0.1747
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0211 0.0279 0.1769
Onchocerca volvulus 0.0218 0.029 0.0396
Loa Loa (eye worm) RNA binding protein 0.0065 0.0046 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0102 0.0105 0.0163
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Trypanosoma cruzi NADH dehydrogenase, putative 0.0094 0.0092 0.0157
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.053 0.0787 0.0979
Schistosoma mansoni rab6-interacting 0.0582 0.0869 0.0869
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.0239 0.0372
Echinococcus multilocularis neurogenic locus notch protein 0.0052 0.0025 0.0025
Mycobacterium tuberculosis Conserved protein 0.029 0.0404 0.099
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0211 0.0279 0.0346
Schistosoma mansoni hypothetical protein 0.007 0.0053 0.0053
Onchocerca volvulus 0.0048 0.0019 0.0025
Entamoeba histolytica hypothetical protein 0.0103 0.0106 0.0128
Onchocerca volvulus 0.0122 0.0137 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0355 0.0508 0.0865
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0061 0.0076
Echinococcus granulosus neurogenic locus protein delta 0.0052 0.0025 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0122 0.0137 0.0335
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0122 0.0137 0.0335
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0038 0.0003 0.0005
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0064 0.0044 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0139 0.0236
Brugia malayi jmjC domain containing protein 0.0443 0.0649 0.1012
Mycobacterium ulcerans short-chain dehydrogenase 0.0122 0.0137 0.0351
Trypanosoma brucei hypothetical protein, conserved 0.0429 0.0626 0.1068
Loa Loa (eye worm) heterochromatin protein 1 0.0914 0.14 0.2182
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0142 0.0168 0.0209
Loa Loa (eye worm) doublecortin family protein 0.0582 0.0869 0.1355
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0011 0.0019
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0122 0.0137 0.0233
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0102 0.0105 0.0105
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Leishmania major hypothetical protein, conserved 0.0122 0.0137 0.0233
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0209
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0094 0.0092 0.0143
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0019 0.0025
Brugia malayi A-kinase anchor protein 10, precursor 0.0103 0.0106 0.0164
Mycobacterium ulcerans acyl-CoA synthetase 0.0218 0.029 0.0742
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Echinococcus granulosus enteropeptidase 0.0065 0.0046 0.0046
Mycobacterium ulcerans monoxygenase 0.0094 0.0092 0.0236
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0122 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0122 0.0137 0.0335
Mycobacterium ulcerans hypothetical protein 0.0055 0.0031 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Leishmania major acetyl-CoA synthetase, putative 0.0064 0.0044 0.0075
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0051 0.0024 0.0036
Schistosoma mansoni nuclear receptor 0.0048 0.0019 0.0018
Trypanosoma brucei phosphomannose isomerase 0.0103 0.0107 0.0181
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.0024 0.0023
Echinococcus granulosus amyloid beta A4 protein 0.0276 0.0382 0.0382
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0137 0.0233
Onchocerca volvulus 0.0733 0.1111 0.152
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0049 0.002 0.0049
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0168 0.0287
Entamoeba histolytica hypothetical protein 0.007 0.0054 0.0063
Treponema pallidum NADH oxidase 0.0355 0.0508 0.0604
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0094 0.0092 0.0184
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0019 0.0025
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1071 0.1649 0.2813
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Onchocerca volvulus Huntingtin homolog 0.0132 0.0153 0.0209
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0094 0.0092 0.0092
Onchocerca volvulus 0.0069 0.0052 0.0071
Entamoeba histolytica Ran family GTPase 0.0043 0.0011 0.001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0355 0.0508 0.0507
Echinococcus granulosus carbonyl reductase 1 0.0122 0.0137 0.0137
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0051 0.0024 0.0057
Brugia malayi glutathione reductase 0.1023 0.1574 0.2454
Brugia malayi Cathepsin L-like precursor 0.0069 0.0052 0.0081
Trypanosoma cruzi phosphomannose isomerase, putative 0.0103 0.0107 0.0181
Brugia malayi Bromodomain containing protein 0.0271 0.0374 0.0583
Brugia malayi oxidoreductase 0.0122 0.0137 0.0213
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.0227 0.0387
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.015 0.0181 0.0221
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0064 0.0044 0.0112
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0098 0.0098 0.0153
Echinococcus granulosus transmembrane protease serine 3 0.0065 0.0046 0.0046
Echinococcus granulosus neurogenic locus notch protein 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0094 0.0092 0.0092
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0016 0.0015
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Loa Loa (eye worm) hypothetical protein 0.0155 0.0189 0.0295
Echinococcus multilocularis retinol dehydrogenase 13 0.0122 0.0137 0.0137
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0094 0.0092 0.0157
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0061 0.0104
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1852 0.2895 0.7095
Mycobacterium ulcerans oxidoreductase 0.0122 0.0137 0.0351
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.105 0.1616 0.4144
Schistosoma mansoni notch 0.0052 0.0025 0.0025
Brugia malayi hypothetical protein 0.0724 0.1096 0.1709
Onchocerca volvulus 0.0582 0.0869 0.119
Onchocerca volvulus 0.0046 0.0016 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0551 0.0821 0.1021
Brugia malayi Delta serrate ligand family protein 0.0052 0.0025 0.0039
Giardia lamblia Kinase, PLK 0.1071 0.1649 0.2051
Onchocerca volvulus 0.0122 0.0137 0.0187
Loa Loa (eye worm) hypothetical protein 0.0042 0.0009 0.0013
Trichomonas vaginalis mercuric reductase, putative 0.0355 0.0508 0.0631
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0115 0.0125 0.0194
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0122 0.0137 0.0335
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0102 0.0105 0.0104
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0122 0.0137 0.0233
Schistosoma mansoni steroid hormone receptor ad4bp 0.0102 0.0105 0.0104
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0103 0.0106 0.0105
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0044 0.0068
Onchocerca volvulus 0.0122 0.0137 0.0187
Mycobacterium tuberculosis Probable dehydrogenase 0.0122 0.0137 0.0335
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0218 0.029 0.0742
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Echinococcus multilocularis jumonji domain containing 1A 0.0117 0.0129 0.0129
Schistosoma mansoni disulfide oxidoreductase 0.0094 0.0092 0.0092
Onchocerca volvulus 0.0052 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0163 0.0202 0.0314
Onchocerca volvulus 0.0069 0.0052 0.0071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0163 0.0202 0.0251
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0103 0.0107 0.0675
Mycobacterium ulcerans aldehyde dehydrogenase 0.0051 0.0024 0.0059
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0355 0.0508 0.0865
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0168 0.0168
Echinococcus granulosus dna polymerase kappa 0.0179 0.0227 0.0227
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.0105 0.0105
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.056 0.0836 0.0836
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0102 0.0105 0.0104
Echinococcus granulosus Chromo domain 0.015 0.0181 0.0181
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0051 0.0024 0.0036
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0102 0.0105 0.0104
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0064 0.0044 0.0107
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0061 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0028 0.0043
Brugia malayi nuclear receptor NHR-88 0.0102 0.0105 0.0163
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0355 0.0508 0.0865
Loa Loa (eye worm) hypothetical protein 0.0163 0.0202 0.0314
Loa Loa (eye worm) hypothetical protein 0.0489 0.0723 0.1126
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Entamoeba histolytica short chain dehydrogenase family protein 0.0122 0.0137 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0069 0.0052 0.0064
Toxoplasma gondii ABC1 family protein 0.029 0.0404 0.081
Echinococcus multilocularis neurogenic locus notch protein 4 0.0052 0.0025 0.0025
Toxoplasma gondii histone lysine methyltransferase SET1 0.0138 0.0163 0.0325
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0094 0.0092 0.1139
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1071 0.1649 0.2572
Loa Loa (eye worm) transcription factor SMAD2 0.0479 0.0706 0.11
Mycobacterium ulcerans aldehyde dehydrogenase 0.0928 0.1422 0.3647
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0179 0.0227 0.0556
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.105 0.1616 0.2755
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0031 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0111 0.0111
Brugia malayi photoreceptor-specific nuclear receptor 0.0102 0.0105 0.0163
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0429 0.0626 0.1606
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0067 0.0049 0.006
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0094 0.0092 0.0157
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Brugia malayi Papain family cysteine protease containing protein 0.0069 0.0052 0.0081
Toxoplasma gondii PAN/Apple domain-containing protein 0.0204 0.0267 0.0534
Echinococcus granulosus axis inhibition protein axin 0.0103 0.0106 0.0106
Echinococcus granulosus Polycystic kidney disease protein 0.0582 0.0869 0.0869
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Onchocerca volvulus 0.0069 0.0052 0.0071
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0094 0.0092 0.0114
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Loa Loa (eye worm) MH2 domain-containing protein 0.0479 0.0706 0.11
Brugia malayi RNA binding protein 0.0065 0.0046 0.0071
Leishmania major hypothetical protein, conserved 0.0117 0.0129 0.022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0054 0.0054
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.0169 0.0262
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0051 0.0024 0.0039
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0122 0.0137 0.0233
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0239 0.0239
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0194 0.0251 0.0428
Brugia malayi Dehydrogenases, short chain protein 30 0.0122 0.0137 0.0213
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0051 0.0024 0.0059
Echinococcus multilocularis enteropeptidase 0.0065 0.0046 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0028 0.0028
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0384 0.0555 0.0555
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0069 0.0052 0.0081
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Echinococcus multilocularis RUN 0.0582 0.0869 0.0869
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0064 0.0044 0.0107
Schistosoma mansoni hypothetical protein 0.004 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0011 0.0022
Loa Loa (eye worm) voltage-dependent calcium channel 0.008 0.007 0.0109
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0122 0.0137 0.0335
Echinococcus granulosus cathepsin l1 0.0046 0.0016 0.0016
Onchocerca volvulus 0.0338 0.0481 0.0657
Leishmania major pteridine reductase 1 0.0122 0.0137 0.0233
Loa Loa (eye worm) hypothetical protein 0.0097 0.0097 0.0151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Schistosoma mansoni slit 0.0052 0.0025 0.0025
Echinococcus granulosus thyroid hormone receptor alpha 0.0048 0.0019 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0102 0.0105 0.0105
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0045 0.0061
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0062 0.0042 0.007
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Echinococcus multilocularis glycoprotein Antigen 5 0.0065 0.0046 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0102 0.0105 0.0163
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0355 0.0508 0.1243
Loa Loa (eye worm) PAN domain-containing protein 0.0204 0.0267 0.0416
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0051 0.0024 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Trypanosoma brucei short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.0061 0.0122
Loa Loa (eye worm) hypothetical protein 0.0093 0.009 0.014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0992 0.1524 0.1524
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Schistosoma mansoni jumonji domain containing protein 0.0117 0.0129 0.0129
Echinococcus multilocularis survival motor neuron protein 1 0.0724 0.1096 0.1096
Loa Loa (eye worm) calcium channel 0.0384 0.0555 0.0865
Chlamydia trachomatis thioredoxin reductase 0.0094 0.0092 0.1467
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0179 0.0227 0.0354
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0122 0.0137 0.0335
Plasmodium falciparum DNA repair protein REV1, putative 0.0055 0.0031 0.0192
Echinococcus granulosus histone lysine methyltransferase setb 0.0583 0.0872 0.0872
Brugia malayi Pre-SET motif family protein 0.4058 0.6413 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0582 0.0869 0.5522
Brugia malayi Cathepsin L-like precursor 0.0069 0.0052 0.0081
Loa Loa (eye worm) dehydrogenase 0.0122 0.0137 0.0213
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0428 0.0624 0.1528
Echinococcus granulosus delta-like protein 1 0.0052 0.0025 0.0025
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.105 0.1616 0.2519
Mycobacterium tuberculosis Probable dehydrogenase 0.2335 0.3665 0.8982
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0094 0.0092 0.0114
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0001 0.0001
Onchocerca volvulus Serine\/threonine kinase homolog 0.1071 0.1649 0.2257
Echinococcus multilocularis flap endonuclease 1 0.0188 0.0242 0.0242
Echinococcus granulosus chromobox protein 1 0.0914 0.14 0.14
Echinococcus multilocularis fat cadherin tumor suppressor 0.0052 0.0025 0.0025
Schistosoma mansoni egf-like domain protein 0.0115 0.0125 0.0124
Brugia malayi Blistered cuticle protein 3 0.0065 0.0045 0.007
Echinococcus multilocularis regulator of G protein signaling 7 0.0103 0.0106 0.0106
Loa Loa (eye worm) pip kinase 2 0.0338 0.0481 0.0749
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0052 0.0025 0.0025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0067 0.0049 0.0049
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0064 0.0044 0.0107
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0064 0.0044 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0054 0.0028 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0031 0.0052
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Echinococcus multilocularis L aminoadipate semialdehyde 0.1526 0.2375 0.2375
Echinococcus multilocularis conserved hypothetical protein 0.0122 0.0137 0.0137
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0355 0.0508 0.8031
Echinococcus granulosus fibropellin Ia 0.0052 0.0025 0.0025
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0038 0.0003 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0218 0.029 0.0742
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0093 0.009 0.014
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0194 0.0251 0.0251
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0094 0.0092 0.0225
Trichomonas vaginalis D-aminoacylase, putative 0.029 0.0404 0.0502
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0045 0.007
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0194 0.0251 0.0391
Loa Loa (eye worm) hypothetical protein 0.0115 0.0125 0.0194
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Onchocerca volvulus Slit protein homolog 0.0052 0.0025 0.0034
Schistosoma mansoni regulator of G protein signaling 0.0103 0.0106 0.0105
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0054 0.0028 0.0043
Echinococcus granulosus tumor protein p63 0.0331 0.0469 0.0469
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0122 0.0137 0.0233
Loa Loa (eye worm) jmjC domain-containing protein 0.0552 0.0822 0.1282
Onchocerca volvulus 0.006 0.0038 0.0051
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0051 0.0024 0.0046
Onchocerca volvulus Arrow homolog 0.0115 0.0125 0.017
Brugia malayi beta-lactamase 0.029 0.0404 0.063
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Leishmania major 4-coumarate:coa ligase-like protein 0.0218 0.029 0.0493
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0044 0.0068
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0069 0.0052 0.0064
Giardia lamblia Flap structure-specific endonuclease 0.0188 0.0242 0.0301
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0045 0.007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Onchocerca volvulus 0.029 0.0404 0.0553
Giardia lamblia PHD finger protein 15 0.0267 0.0368 0.0458
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0094 0.0092 0.0111
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0209
Mycobacterium leprae conserved hypothetical protein 0.029 0.0404 0.099
Leishmania major cathepsin L-like protease 0.0263 0.0361 0.0615
Trypanosoma cruzi DNA damage repair protein, putative 0.0055 0.0031 0.0052
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0168 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Trypanosoma brucei exonuclease, putative 0.0038 0.0003 0.0005
Echinococcus granulosus cathepsin l cysteine peptidase 0.0069 0.0052 0.0052
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.015 0.0181 0.018
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0094 0.0092 0.0236
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0065 0.0046 0.0071
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0022 0.0033
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0094 0.0092 0.0225
Loa Loa (eye worm) jmjC domain-containing protein 0.0117 0.0129 0.0201
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Plasmodium vivax SET domain protein, putative 0.0583 0.0872 0.5538
Trypanosoma brucei chrX additional, unordered contigs 0.0055 0.0031 0.0052
Echinococcus granulosus L aminoadipate semialdehyde 0.1526 0.2375 0.2375
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0102 0.0105 0.0143
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0122 0.0137 0.0233
Loa Loa (eye worm) beta-lactamase 0.029 0.0404 0.063
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Schistosoma mansoni flap endonuclease-1 0.017 0.0213 0.0213
Brugia malayi AMP-binding enzyme family protein 0.0218 0.029 0.0451
Trichomonas vaginalis steroid dehydrogenase, putative 0.0122 0.0137 0.017
Schistosoma mansoni chromobox protein 0.015 0.0181 0.018
Echinococcus granulosus snurportin 1 0.0956 0.1467 0.1467
Onchocerca volvulus 0.0204 0.0267 0.0365
Mycobacterium ulcerans oxidoreductase 0.0122 0.0137 0.0351
Echinococcus multilocularis retinol dehydrogenase 11 0.0122 0.0137 0.0137
Brugia malayi Calcium binding EGF domain containing protein 0.0052 0.0025 0.0039
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0051 0.0024 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0211 0.0279 0.0346
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.015 0.0181 0.0221
Leishmania major DNA polymerase kappa, putative 0.0055 0.0031 0.0052
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0094 0.0092 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.015 0.0181 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0105 0.0163
Brugia malayi dehydrogenases, short chain protein 2 0.0122 0.0137 0.0213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0582 0.0869 0.1355
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0038 0.0003 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0012 0.0012
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0044 0.0075
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0019 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0044 0.0051
Brugia malayi Muscle positioning protein 4 0.0052 0.0025 0.0039
Brugia malayi follicle stimulating hormone receptor 0.0484 0.0714 0.1112
Giardia lamblia Alcohol dehydrogenase 0.0051 0.0024 0.0029
Brugia malayi jmjC domain containing protein 0.0117 0.0129 0.0201
Leishmania major aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.029 0.0404 0.063
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0044 0.0068
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0122 0.0137 0.0213
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0051 0.0024 0.0057
Schistosoma mansoni glutamate synthase 0.0094 0.0092 0.0092
Toxoplasma gondii selenide, water dikinase 0.0094 0.0092 0.0184
Plasmodium vivax heterochromatin protein 1, putative 0.015 0.0181 0.1146
Echinococcus granulosus carbonyl reductase 1 0.0122 0.0137 0.0137
Echinococcus multilocularis beta adrenergic receptor kinase 0.0106 0.0111 0.0111
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0064 0.0044 0.0112
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Brugia malayi hypothetical protein 0.01 0.0102 0.0158
Mycobacterium ulcerans dehydrogenase/reductase 0.0122 0.0137 0.0351
Onchocerca volvulus 0.0122 0.0137 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.0105 0.0163
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0045 0.007
Schistosoma mansoni sulfide quinone reductase 0.0094 0.0092 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Trypanosoma cruzi major cysteine proteinase, putative 0.0207 0.0272 0.0462
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.029 0.0404 0.099
Trichomonas vaginalis DNA polymerase eta, putative 0.0179 0.0227 0.0282
Loa Loa (eye worm) CHromoDomain protein family member 0.0153 0.0186 0.029
Onchocerca volvulus 0.0204 0.0267 0.0365
Trypanosoma brucei unspecified product 0.0123 0.0139 0.0236
Loa Loa (eye worm) hypothetical protein 0.029 0.0404 0.063
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0064 0.0044 0.0107
Echinococcus granulosus hypothetical protein 0.0122 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0106 0.0131
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0094 0.0092 0.0092
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0218 0.029 0.0709
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0022 0.0033
Trypanosoma cruzi DNA polymerase eta, putative 0.0055 0.0031 0.0052
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0218 0.029 0.0742
Schistosoma mansoni jumonji domain containing protein 0.0812 0.1237 0.1237
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Toxoplasma gondii PAN domain-containing protein 0.0204 0.0267 0.0534
Echinococcus multilocularis lysine specific demethylase 6a 0.0117 0.0129 0.0129
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0142 0.0168 0.0287
Schistosoma mansoni hypothetical protein 0.0065 0.0046 0.0045
Giardia lamblia Glutamate synthase 0.0094 0.0092 0.0114
Echinococcus multilocularis lipoxygenase domain containing protein 0.0582 0.0869 0.0869
Onchocerca volvulus 0.0195 0.0253 0.0345
Brugia malayi CHD4 protein 0.0153 0.0186 0.029
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Onchocerca volvulus 0.0122 0.0137 0.0187
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0067 0.0049 0.0076
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0163 0.0202 0.0493
Trypanosoma brucei short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Trichomonas vaginalis glutamate synthase, putative 0.0094 0.0092 0.0114
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0064 0.0044 0.0278
Echinococcus granulosus hypothetical protein 0.0122 0.0137 0.0137
Schistosoma mansoni nuclear hormone receptor 0.0102 0.0105 0.0104
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0137 0.0233
Toxoplasma gondii calcium binding egf domain-containing protein 0.0115 0.0125 0.0249
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0038 0.0003 0.0005
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0044 0.0012 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0189 0.0322
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.2481 0.3898 0.9553
Mycobacterium ulcerans NADH dehydrogenase 0.0094 0.0092 0.0236
Schistosoma mansoni aldehyde dehydrogenase 0.0928 0.1422 0.1422
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0211 0.0279 0.0346
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0044 0.0107
Toxoplasma gondii subtilisin SUB12 0.0204 0.0267 0.0534
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.1526 0.2375 0.2375
Trypanosoma cruzi hypothetical protein, conserved 0.0094 0.0092 0.0157
Leishmania major hypothetical protein, conserved 0.029 0.0404 0.0689
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0094 0.0092 0.0157
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0168 0.1068
Brugia malayi polk-prov protein 0.0055 0.0031 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0163 0.0202 0.0251
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0072 0.0057 0.007
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0122 0.0137 0.0187
Mycobacterium tuberculosis Probable hydrolase 0.029 0.0404 0.099
Trichomonas vaginalis exonuclease%2C+putative 0.0038 0.0003 0.0003
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0045 0.007
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0127 0.0144 0.0288
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0274
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0093 0.009 0.0112
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0048 0.0019 0.0018
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0122 0.0137 0.0869
Trypanosoma cruzi cysteine peptidase, putative 0.0263 0.0361 0.0615
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0103 0.0107 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0137 0.0233
Brugia malayi Cathepsin L-like precursor 0.0069 0.0052 0.0081
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0194 0.0251 0.0644
Trypanosoma brucei DNA polymerase eta, putative 0.0179 0.0227 0.0387
Echinococcus multilocularis beta LACTamase domain containing family member 0.029 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0064 0.0044 0.0051
Onchocerca volvulus 0.0052 0.0025 0.0034
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0106 0.0111 0.0173
Onchocerca volvulus Cathepsin L homolog 0.0069 0.0052 0.0071
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0087 0.0552
Brugia malayi hypothetical protein 0.0264 0.0363 0.0566
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0103 0.0106 0.0106
Toxoplasma gondii hypothetical protein 0.0204 0.0267 0.0534
Trichomonas vaginalis chromobox protein, putative 0.015 0.0181 0.0224
Schistosoma mansoni axis inhibition protein axin 0.0103 0.0106 0.0105
Echinococcus granulosus thioredoxin glutathione reductase 0.1031 0.1586 0.1586
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0355 0.0508 0.0865
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0122 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Mycobacterium ulcerans acetyl-CoA synthetase 0.0064 0.0044 0.0112
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0051 0.0024 0.0023
Onchocerca volvulus 0.015 0.0181 0.0247
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0992 0.1524 0.1524
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0261 0.0358 0.0557
Brugia malayi Cadherin domain containing protein 0.0052 0.0025 0.0039
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.015 0.0181 0.0224
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Onchocerca volvulus 0.0052 0.0025 0.0034
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0094 0.0092 0.0114
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0094 0.0092 0.0143
Schistosoma mansoni DNA polymerase IV / kappa 0.0055 0.0031 0.003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0102 0.0105 0.0104
Echinococcus multilocularis regulator of G protein signaling 3 0.0103 0.0106 0.0106
Brugia malayi Cathepsin L-like precursor 0.0046 0.0016 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0733 0.1111 0.111
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0429 0.0626 1
Plasmodium falciparum DNA repair protein RAD2, putative 0.0038 0.0003 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0102 0.0105 0.0163
Trypanosoma cruzi cruzipain precursor, putative 0.0263 0.0361 0.0615
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0168 0.0168
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0064 0.0044 0.0112
Echinococcus granulosus protein jagged 2 0.0052 0.0025 0.0025
Trypanosoma cruzi phosphomannose isomerase, putative 0.0103 0.0107 0.0181
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0094 0.0092 0.0092
Echinococcus granulosus citrate lyase subunit beta protein 0.0428 0.0624 0.0624
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.1526 0.2375 0.3703
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0928 0.1422 0.2425
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Loa Loa (eye worm) aldehyde dehydrogenase 0.0051 0.0024 0.0036
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0218 0.029 0.0709
Echinococcus granulosus chromobox protein 2 0.015 0.0181 0.0181
Mycobacterium tuberculosis Conserved protein 0.029 0.0404 0.099
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0153 0.0186 0.0186
Brugia malayi AMP-binding enzyme family protein 0.0218 0.029 0.0451
Giardia lamblia High cysteine protein 0.0052 0.0025 0.0031
Schistosoma mansoni regulator of G protein signaling 0.0114 0.0124 0.0124
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0064 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Brugia malayi notch-like transmembrane receptor 0.0052 0.0025 0.0039
Schistosoma mansoni hypothetical protein 0.0956 0.1467 0.1466
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0428 0.0624 0.0776
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0218 0.029 0.0451
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0044 0.0012 0.002
Leishmania major hypothetical protein, conserved 0.0122 0.0137 0.0233
Echinococcus granulosus protein jagged 2 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0019 0.0018
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0019 0.0019
Echinococcus multilocularis protein patched 0.0042 0.0009 0.0009
Trichomonas vaginalis flap endonuclease-1, putative 0.0038 0.0003 0.0003
Toxoplasma gondii microneme protein MIC4 0.0204 0.0267 0.0534
Brugia malayi Flap endonuclease-1 0.0188 0.0242 0.0377
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0247 0.0336 0.0523
Plasmodium falciparum thioredoxin reductase 0.0355 0.0508 0.3223
Schistosoma mansoni hypothetical protein 0.0582 0.0869 0.0869
Loa Loa (eye worm) DnaJ domain-containing protein 0.0061 0.004 0.0061
Echinococcus granulosus protein jagged 1 0.0052 0.0025 0.0025
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0044 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0218 0.029 0.0451
Loa Loa (eye worm) hypothetical protein 0.029 0.0404 0.063
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0338 0.0481 0.048
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0179 0.0227 0.0282
Brugia malayi Retinol dehydrogenase 12 0.0122 0.0137 0.0213
Schistosoma mansoni importin beta-1 0.009 0.0085 0.0085
Leishmania major importin beta-1 subunit, putative 0.0073 0.0058 0.0098
Trypanosoma cruzi short chain dehydrogenase, putative 0.0122 0.0137 0.0233
Echinococcus multilocularis fibropellin Ia 0.0052 0.0025 0.0025
Onchocerca volvulus 0.0065 0.0045 0.0061
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Giardia lamblia DNA damage repair protein 0.0055 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Mycobacterium ulcerans hypothetical protein 0.0428 0.0624 0.16
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0102 0.0105 0.0163
Toxoplasma gondii carbonyl reductase 1, putative 0.0122 0.0137 0.0274
Onchocerca volvulus 0.0069 0.0052 0.0071
Echinococcus multilocularis snurportin 1 0.0956 0.1467 0.1467
Trypanosoma brucei hypothetical protein, conserved 0.0094 0.0092 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0102 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0046 0.0016 0.0024
Toxoplasma gondii microneme protein, putative 0.0204 0.0267 0.0534
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0088
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0168 0.0168
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0122 0.0137 0.0274
Toxoplasma gondii cathepsin CPL 0.0069 0.0052 0.0104
Brugia malayi Glycosyl hydrolases family 31 protein 0.0337 0.0479 0.0746
Loa Loa (eye worm) hypothetical protein 0.0115 0.0125 0.0194
Schistosoma mansoni alpha-glucosidase 0.029 0.0404 0.0404
Trichomonas vaginalis antibiotic synthetase, putative 0.0064 0.0044 0.0054
Onchocerca volvulus 0.0064 0.0044 0.006
Loa Loa (eye worm) hypothetical protein 0.0069 0.0052 0.0081
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Schistosoma mansoni septate junction protein 0.0052 0.0025 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0218 0.029 0.0709
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0094 0.0092 0.0184
Echinococcus multilocularis peregrin 0.0271 0.0374 0.0374
Plasmodium vivax hypothetical protein, conserved 0.029 0.0404 0.2567
Mycobacterium leprae Probable lipase LipE 0.029 0.0404 0.099
Onchocerca volvulus 0.0186 0.0239 0.0327
Schistosoma mansoni kinase 0.0544 0.081 0.0809
Onchocerca volvulus 0.0122 0.0137 0.0187
Echinococcus multilocularis fibrillin 1 0.0115 0.0125 0.0125
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0049 0.002 0.0031
Echinococcus granulosus glycoprotein Antigen 5 0.0065 0.0046 0.0046
Brugia malayi hypothetical protein 0.0122 0.0137 0.0213
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0065 0.0046 0.0046
Echinococcus multilocularis amyloid beta A4 protein 0.0276 0.0382 0.0382
Brugia malayi PXA domain containing protein 0.0103 0.0106 0.0164
Echinococcus multilocularis retinol dehydrogenase 11 0.0122 0.0137 0.0137
Echinococcus multilocularis Chromobox protein 3 0.015 0.0181 0.0181
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0428 0.0624 0.16
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0157 0.0192 0.0239
Trypanosoma cruzi polo-like protein kinase, putative 0.1071 0.1649 0.2813
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0048 0.0019 0.0029
Toxoplasma gondii PAN domain-containing protein 0.0204 0.0267 0.0534
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.015 0.0181 0.0361
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0097 0.0097
Loa Loa (eye worm) cysteine protease 0.0069 0.0052 0.0081
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0168 0.0168
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0094 0.0092 0.0225
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0049 0.002 0.0049
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.007 0.0053 0.0053
Onchocerca volvulus 0.0048 0.0019 0.0026
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0036
Mycobacterium tuberculosis Probable oxidoreductase 0.2595 0.408 1
Entamoeba histolytica hypothetical protein 0.015 0.0181 0.0221
Loa Loa (eye worm) hypothetical protein 0.0054 0.0028 0.0043
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0051 0.0024 0.0059
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0051 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0179 0.0227 0.0354
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0429 0.0626 0.0752
Leishmania major phosphomannose isomerase 0.0103 0.0107 0.0181
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0011 0.0014
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0287
Loa Loa (eye worm) hypothetical protein 0.0115 0.0125 0.0194
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0011 0.0019
Trichomonas vaginalis antibiotic synthetase, putative 0.0064 0.0044 0.0054
Brugia malayi hypothetical protein 0.0582 0.0869 0.1355
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Leishmania major hypothetical protein, conserved 0.3713 0.5863 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0429 0.0626 0.1068
Schistosoma mansoni hypothetical protein 0.0087 0.0081 0.0081
Brugia malayi Cathepsin L-like cysteine proteinase 0.0046 0.0016 0.0024
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0122 0.0137 0.0137
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0046 0.0045
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0137 0.0335
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.007 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0009 0.001
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0094 0.0092 0.0184
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Loa Loa (eye worm) hypothetical protein 0.0054 0.0028 0.0043
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0429 0.0626 1
Plasmodium falciparum glutathione reductase 0.1023 0.1574 1
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.0024 0.0023
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0064 0.0044 0.0112
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0122 0.0137 0.0233
Echinococcus multilocularis Polycystic kidney disease protein 0.0582 0.0869 0.0869
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.2335 0.3665 0.8982
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0048 0.0019 0.0019
Brugia malayi Calcium binding EGF domain containing protein 0.0052 0.0025 0.0039
Echinococcus multilocularis cpg binding protein 0.0063 0.0043 0.0043
Onchocerca volvulus 0.0204 0.0267 0.0365
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0064 0.0044 0.0107
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0122 0.0137 0.0233
Leishmania major DNA damage repair protein, putative 0.0055 0.0031 0.0052
Leishmania major aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Echinococcus multilocularis FTZ F1 alpha 0.0102 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Brugia malayi nuclear receptor NHR-88 0.0048 0.0019 0.0029
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0087 0.0081 0.0138
Giardia lamblia Reductase, putative 0.0122 0.0137 0.017
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Echinococcus granulosus sentrin specific protease 8 0.0072 0.0057 0.0057
Toxoplasma gondii EGF family domain-containing protein 0.0052 0.0025 0.005
Echinococcus multilocularis notch 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0122 0.0137 0.0274
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Brugia malayi jmjC domain containing protein 0.0117 0.0129 0.0201
Toxoplasma gondii LsmAD domain-containing protein 0.0155 0.0189 0.0379
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0094 0.0092 0.0114
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0056 0.0031 0.0076
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0052 0.0025 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Toxoplasma gondii transporter, cation channel family protein 0.008 0.007 0.014
Onchocerca volvulus 0.0065 0.0045 0.0061
Schistosoma mansoni cell polarity protein 0.0052 0.0025 0.0025
Entamoeba histolytica hypothetical protein 0.0103 0.0106 0.0128
Schistosoma mansoni cathepsin F (C01 family) 0.0069 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0115 0.0125 0.0194
Mycobacterium ulcerans hypothetical protein 0.029 0.0404 0.1036
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Echinococcus multilocularis transient receptor potential cation channel 0.0122 0.0137 0.0137
Schistosoma mansoni voltage-gated cation channel 0.0384 0.0555 0.0555
Echinococcus granulosus flap endonuclease GEN 1 0.0038 0.0003 0.0003
Echinococcus multilocularis cysteine protease 0.0069 0.0052 0.0052
Brugia malayi F/Y-rich N-terminus family protein 0.0127 0.0145 0.0225
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0065 0.0046 0.0046
Toxoplasma gondii PAN domain-containing protein 0.0204 0.0267 0.0534
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0163 0.0202 0.3216
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0051 0.0024 0.0025
Echinococcus granulosus Chromobox protein 3 0.015 0.0181 0.0181
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0338 0.0481 0.048
Plasmodium vivax thioredoxin reductase, putative 0.1023 0.1574 1
Mycobacterium ulcerans carveol-like dehydrogenase 0.0122 0.0137 0.0351
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0091 0.0087 0.0552
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Echinococcus granulosus arachidonate 5 lipoxygenase 0.2392 0.3756 0.3756
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0094 0.0092 0.0236
Echinococcus multilocularis oxidoreductase 0.0122 0.0137 0.0137
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0044 0.0044
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.0061 0.0061
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Echinococcus granulosus beta-adrenergic receptor kinase 0.0106 0.0111 0.0111
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0188 0.0242 0.0485
Brugia malayi Doublecortin family protein 0.0582 0.0869 0.1355
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Plasmodium vivax ataxin-2 like protein, putative 0.0155 0.0189 0.1201
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0051 0.0024 0.0057
Echinococcus multilocularis lipoxygenase domain containing protein 0.0582 0.0869 0.0869
Schistosoma mansoni lipoxygenase 0.2392 0.3756 0.3756
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0355 0.0508 0.3223
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0429 0.0626 0.1606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0102 0.0105 0.0163
Schistosoma mansoni carbonyl reductase 0.0122 0.0137 0.0137
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0168 0.0168
Onchocerca volvulus 0.0069 0.0052 0.0071
Echinococcus multilocularis neural cadherin 0.0052 0.0025 0.0025
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0429 0.0626 0.3978
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0355 0.0508 0.8031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Leishmania major GTP-binding protein, putative 0.0043 0.0011 0.0019
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0094 0.0092 0.0157
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0094 0.0092 0.0236
Onchocerca volvulus 0.0122 0.0137 0.0187
Entamoeba histolytica acyl-coA synthetase, putative 0.0218 0.029 0.0356
Echinococcus multilocularis transmembrane protease serine 3 0.0065 0.0046 0.0046
Trichomonas vaginalis apoptosis inducing factor, putative 0.0094 0.0092 0.0114
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0355 0.0508 0.3223
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0036
Brugia malayi conserved hypotetical protein 0.0048 0.0019 0.0029
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0003 0.0017
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0512 0.0759 0.1039
Echinococcus multilocularis protein jagged 2 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0264 0.0363 0.0566
Loa Loa (eye worm) hypothetical protein 0.0163 0.0202 0.0314
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.105 0.1616 0.4144
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Plasmodium falciparum thioredoxin reductase 0.1023 0.1574 1
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0051 0.0024 0.0039
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0122 0.0137 0.0233
Loa Loa (eye worm) nuclear receptor NHR-67 0.0048 0.0019 0.0029
Leishmania major trypanothione reductase 0.1023 0.1574 0.2684
Schistosoma mansoni aldehyde dehydrogenase 0.0928 0.1422 0.1422
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0122 0.0137 0.0233
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.029 0.0404 0.1036
Onchocerca volvulus 0.0065 0.0046 0.0062
Echinococcus multilocularis glutamate synthase 0.0094 0.0092 0.0092
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0142 0.0168 0.0337
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0009 0.0013
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0069 0.0052 0.0052
Entamoeba histolytica phosphomannose isomerase, putative 0.0103 0.0107 0.0129
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0139 0.0236
Echinococcus multilocularis steroid dehydrogenase 0.0122 0.0137 0.0137
Schistosoma mansoni chromobox protein 0.0914 0.14 0.1399
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0044 0.0107
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus multilocularis carbonyl reductase 1 0.0122 0.0137 0.0137
Echinococcus multilocularis ubiquitin specific protease 41 0.0067 0.0049 0.0049
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0582 0.0869 0.1355
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0209
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Schistosoma mansoni hypothetical protein 0.007 0.0054 0.0053
Trichomonas vaginalis chromobox protein, putative 0.0551 0.0821 0.1021
Plasmodium falciparum cysteine proteinase falcipain 3 0.0069 0.0052 0.0329
Plasmodium vivax ferrodoxin reductase, putative 0.0094 0.0092 0.0584
Brugia malayi Valyl-tRNA synthetase 0.015 0.0181 0.0281
Brugia malayi PHD-finger family protein 0.0267 0.0368 0.0574
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0206
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Brugia malayi Fibulin-1 precursor 0.0115 0.0125 0.0194
Schistosoma mansoni coup transcription factor 0.0102 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0115 0.0125 0.0194
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0142 0.0168 0.0431
Echinococcus multilocularis chromobox protein 2 0.015 0.0181 0.0181
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0009 0.001
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0019 0.0018
Brugia malayi Cadherin domain containing protein 0.0052 0.0025 0.0039
Giardia lamblia Exonuclease 1 0.0038 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0019 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0105 0.0104
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0051 0.0024 0.0039
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.0102 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0384 0.0555 0.0555
Onchocerca volvulus Alhambra homolog 0.0267 0.0368 0.0504
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0044 0.0075
Trichomonas vaginalis esterase, putative 0.029 0.0404 0.0502
Trichomonas vaginalis Sentrin-specific protease, putative 0.0072 0.0057 0.007
Loa Loa (eye worm) acetyltransferase 0.0142 0.0169 0.0262
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0122 0.0137 0.017
Brugia malayi Pre-SET motif family protein 0.0583 0.0872 0.1359
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0094 0.0092 0.0225
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0103 0.0107 0.0107
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0168 0.0168
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0051 0.0024 0.0025
Trichomonas vaginalis importin beta-1, putative 0.0073 0.0058 0.0072
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0122 0.0137 0.0233
Schistosoma mansoni regulator of G protein signaling 0.0103 0.0106 0.0105
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0164
Schistosoma mansoni notch 0.0052 0.0025 0.0025
Leishmania major short chain dehydrogenase-like protein 0.0122 0.0137 0.0233
Toxoplasma gondii HEAT repeat-containing protein 0.009 0.0085 0.0169
Echinococcus multilocularis slit 2 protein 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0164
Onchocerca volvulus Cathepsin F homolog 0.0069 0.0052 0.0071
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.0061 0.0076
Onchocerca volvulus 0.0064 0.0044 0.006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.0105 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Leishmania major aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Entamoeba histolytica cysteine proteinase, putative 0.0069 0.0052 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0111 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.015 0.0181 0.0361
Plasmodium vivax hypothetical protein, conserved 0.015 0.0181 0.1146
Leishmania major hypothetical protein, conserved 0.0122 0.0137 0.0233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0338 0.0481 0.0481
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.003 0.0072
Trypanosoma brucei DNA damage repair protein, putative 0.0055 0.0031 0.0052
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0064 0.0044 0.0044
Echinococcus multilocularis neurogenic locus notch protein 0.0052 0.0025 0.0025
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0122 0.0137 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0038 0.0003 0.0005
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0094 0.0092 0.0111
Trichomonas vaginalis flap endonuclease-1, putative 0.0188 0.0242 0.0301
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0011 0.0017
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0204 0.0267 0.0534
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0045 0.007
Loa Loa (eye worm) hypothetical protein 0.0064 0.0044 0.0068
Brugia malayi ecdysteroid receptor 0.0102 0.0105 0.0163
Trypanosoma cruzi DNA damage repair protein, putative 0.0055 0.0031 0.0052
Echinococcus granulosus neurogenic locus notch protein 0.0052 0.0025 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0046 0.0045
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0094 0.0092 0.0092
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Brugia malayi Aldehyde dehydrogenase protein 4 0.0051 0.0024 0.0036
Echinococcus multilocularis lysine specific demethylase 5A 0.044 0.0644 0.0644
Brugia malayi aldehyde dehydrogenase 0.0051 0.0024 0.0036
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0355 0.0508 0.0791
Toxoplasma gondii NADPH-glutathione reductase 0.0355 0.0508 0.1017
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0051 0.0024 0.0059
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0009 0.0009
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0218 0.029 0.0742
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0102 0.0105 0.0163
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Loa Loa (eye worm) Ulp1 protease 0.0072 0.0057 0.0088
Echinococcus granulosus dna polymerase eta 0.0179 0.0227 0.0227
Echinococcus granulosus regulator of G protein signaling 7 0.0103 0.0106 0.0106
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0177 0.0276
Trichomonas vaginalis ran, putative 0.0043 0.0011 0.0014
Onchocerca volvulus 0.0065 0.0046 0.0062
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0064 0.0044 0.0112
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0087 0.0081 0.0138
Trypanosoma brucei short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Entamoeba histolytica cysteine proteinase, putative 0.0069 0.0052 0.0061
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Trypanosoma cruzi hypothetical protein, conserved 0.0094 0.0092 0.0157
Plasmodium falciparum flap endonuclease 1 0.0188 0.0242 0.1536
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0058 0.0072
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Brugia malayi XPG I-region family protein 0.0038 0.0003 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0137 0.0335
Mycobacterium tuberculosis Conserved protein 0.029 0.0404 0.099
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Mycobacterium tuberculosis Probable conserved lipoprotein 0.029 0.0404 0.099
Loa Loa (eye worm) dehydrogenase 0.0122 0.0137 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Schistosoma mansoni hypothetical protein 0.0065 0.0046 0.0045
Entamoeba histolytica acyl-CoA synthetase, putative 0.0218 0.029 0.0356
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0115 0.0125 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Loa Loa (eye worm) hypothetical protein 0.0054 0.0028 0.0043
Onchocerca volvulus 0.0048 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0163 0.0202 0.0314
Brugia malayi CXXC zinc finger family protein 0.006 0.0038 0.0058
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Plasmodium vivax JmjC domain containing protein 0.0117 0.0129 0.0819
Schistosoma mansoni hypothetical protein 0.004 0.0006 0.0006
Brugia malayi PXA domain containing protein 0.0103 0.0106 0.0164
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0051 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0073 0.0058 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.3713 0.5863 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0355 0.0508 0.1017
Entamoeba histolytica cysteine protease, putative 0.0069 0.0052 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.0227 0.0387
Brugia malayi Dehydrogenases, short chain protein 2 0.0122 0.0137 0.0213
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Onchocerca volvulus Putative cubilin 0.0052 0.0025 0.0034
Brugia malayi Raf kinase 0.0044 0.0012 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0044 0.0068
Echinococcus granulosus neurogenic locus notch protein 4 0.0052 0.0025 0.0025
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0051 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0218 0.029 0.0451
Toxoplasma gondii PAN domain-containing protein 0.3165 0.4989 1
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0094 0.0092 0.0584
Loa Loa (eye worm) RGS-3 protein 0.0103 0.0106 0.0164
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0004
Brugia malayi tailless protein 0.0048 0.0019 0.0029
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0122 0.0137 0.0233
Schistosoma mansoni protein phosphatase 2C 0.0117 0.0129 0.0129
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.01 0.0099
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0122 0.0137 0.0351
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.5078 0.804 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0094 0.0092 0.0114
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0009 0.0053
Schistosoma mansoni polycystin 1-related 0.0582 0.0869 0.0869
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0051 0.0024 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0106 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0064 0.0044 0.0068
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0094 0.0092 0.0225
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0046 0.0045
Echinococcus multilocularis sentrin specific protease 8 0.0072 0.0057 0.0057
Trypanosoma brucei hypothetical protein, conserved 0.0055 0.0031 0.0052
Brugia malayi Cathepsin L-like precursor 0.0069 0.0052 0.0081
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0132 0.0153 0.0239
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0142 0.0168 0.2685
Schistosoma mansoni regulator of G protein signaling 0.0103 0.0106 0.0105
Schistosoma mansoni hypothetical protein 0.0094 0.0092 0.0092
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0267 0.0368 0.0574
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0009 0.0017
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0122 0.0137 0.1885
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0355 0.0508 0.1302
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Mycobacterium ulcerans esterase/lipase LipP 0.029 0.0404 0.1036
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0094 0.0092 0.0157
Brugia malayi Type III restriction enzyme, res subunit family protein 0.015 0.0181 0.0281
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0094 0.0092 0.0225
Loa Loa (eye worm) histone methyltransferase 0.004 0.0006 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0003 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Brugia malayi nuclear receptor NHR-67 0.0048 0.0019 0.0029
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0122 0.0137 0.0335
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0094 0.0092 0.0225
Schistosoma mansoni RAR-like nuclear receptor 0.0102 0.0105 0.0104
Brugia malayi Probable ATP-dependent helicase DHX35 0.0159 0.0196 0.0305
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0051 0.0024 0.0059
Brugia malayi hypothetical protein 0.0065 0.0045 0.007
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0109
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Echinococcus granulosus lysine specific demethylase 5A 0.0443 0.0649 0.0649
Mycobacterium ulcerans short-chain dehydrogenase 0.0122 0.0137 0.0351
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0019 0.0019
Echinococcus multilocularis axis inhibition protein axin 0.0103 0.0106 0.0106
Leishmania major DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Trichomonas vaginalis protein kinase inhibitor, putative 0.0061 0.004 0.0049
Toxoplasma gondii PHD-finger domain-containing protein 0.0267 0.0368 0.0738
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0049 0.006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0049 0.0083
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0094 0.0092 0.0111
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0065 0.0046 0.0045
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0072 0.0057 0.007
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0429 0.0626 0.1534
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0142 0.0168 0.1068
Loa Loa (eye worm) hypothetical protein 0.0046 0.0016 0.0024
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0117 0.0129 0.022
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Plasmodium falciparum phd finger protein, putative 0.0267 0.0368 0.2339
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0049 0.006
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0048 0.0019 0.0018
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0117 0.0129 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0239 0.0239
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.0061 0.0104
Echinococcus multilocularis tumor protein p63 0.0331 0.0469 0.0469
Echinococcus granulosus cpg binding protein 0.0063 0.0043 0.0043
Mycobacterium ulcerans DNA polymerase IV 0.0179 0.0227 0.0582
Onchocerca volvulus 0.0094 0.0092 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0055 0.0031 0.0052
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0051 0.0024 0.0046
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Onchocerca volvulus 0.0122 0.0137 0.0187
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0137 0.0335
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0045 0.007
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0093 0.009 0.0112
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0206
Leishmania major hypothetical protein, conserved 0.0094 0.0092 0.0157
Echinococcus multilocularis regulator of G protein signaling 7 0.0103 0.0106 0.0106
Onchocerca volvulus 0.0065 0.0045 0.0061
Loa Loa (eye worm) jmjC domain-containing protein 0.0117 0.0129 0.0201
Onchocerca volvulus 0.0122 0.0137 0.0187
Schistosoma mansoni hypothetical protein 0.0169 0.0212 0.0212
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0061 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0102 0.0105 0.0163
Brugia malayi hypothetical protein 0.0054 0.0028 0.0043
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0267 0.0368 0.0368
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0153 0.0186 0.0186
Echinococcus granulosus ubiquitin specific protease 41 0.0067 0.0049 0.0049
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0179 0.0227 0.0387
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.015 0.0181 0.018
Loa Loa (eye worm) ctsf protein 0.0069 0.0052 0.0081
Schistosoma mansoni jumonji/arid domain-containing protein 0.0443 0.0649 0.0649
Plasmodium vivax flap endonuclease 1, putative 0.0188 0.0242 0.1536
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Trichomonas vaginalis D-aminoacylase, putative 0.029 0.0404 0.0502
Leishmania major hypothetical protein, conserved 0.0122 0.0137 0.0233
Toxoplasma gondii propionate-CoA ligase 0.0064 0.0044 0.0088
Echinococcus granulosus expressed protein 0.191 0.2989 0.2989
Onchocerca volvulus Protein ultraspiracle homolog 0.0102 0.0105 0.0143
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Echinococcus granulosus neural cadherin 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Echinococcus granulosus lipoxygenase domain containing protein 0.0582 0.0869 0.0869
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0045 0.0061
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0069 0.0052 0.0329
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0006 0.0006
Giardia lamblia Fructose-bisphosphate aldolase 0.5078 0.804 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0583 0.0872 0.0872
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0044 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0102 0.0105 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0016 0.0016
Mycobacterium ulcerans hypothetical protein 0.0094 0.0092 0.0236
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0094 0.0092 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0443 0.0649 0.1012
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0122 0.0137 0.0351
Echinococcus granulosus dnaJ subfamily C 6 0.0061 0.004 0.004
Echinococcus granulosus importin subunit beta 1 0.009 0.0085 0.0085
Plasmodium vivax glutathione reductase, putative 0.1023 0.1574 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0102 0.0105 0.0105
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0093 0.009 0.0153
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0106 0.0131
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0051 0.0024 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Echinococcus multilocularis lysosomal alpha glucosidase 0.0337 0.0479 0.0479
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0122 0.0137 0.0233
Brugia malayi Cathepsin L-like precursor 0.0046 0.0016 0.0024
Trichomonas vaginalis Heterochromatin protein, putative 0.015 0.0181 0.0224
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0137 0.0335
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0102 0.0105 0.0105
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0163 0.0202 0.0251
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0094 0.0092 0.0092
Echinococcus multilocularis microtubule associated protein 2 0.6308 1 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0106 0.0111 0.0173
Brugia malayi nuclear hormone receptor 0.0102 0.0105 0.0163
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0051 0.0024 0.0057
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.015 0.0181 0.1146
Loa Loa (eye worm) hypothetical protein 0.0054 0.0028 0.0043
Leishmania major dehydrogenase-like protein 0.0122 0.0137 0.0233
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.029 0.0404 0.099
Echinococcus multilocularis voltage dependent calcium channel 0.0384 0.0555 0.0555
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0094 0.0092 0.0184
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0064 0.0044 0.0107
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0097 0.0151
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Brugia malayi hypothetical protein 0.0303 0.0425 0.0661
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.015 0.0181 0.0224
Schistosoma mansoni loxhd1 0.0582 0.0869 0.0869
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Loa Loa (eye worm) hypothetical protein 0.029 0.0404 0.063
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0038 0.0058
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0067 0.0049 0.012
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0287
Schistosoma mansoni nuclear receptor nhr-48 0.0048 0.0019 0.0018
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0163 0.0202 0.0202
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0051 0.0024 0.0039
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0048 0.0019 0.0029
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0094 0.0092 0.0157
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0121 0.0135 0.0135
Mycobacterium leprae conserved hypothetical protein 0.0429 0.0626 0.1534
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0163 0.0202 0.0517
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0061 0.0095
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0088
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.015 0.0181 0.1146
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0103 0.0106 0.0131
Plasmodium falciparum acyl-CoA synthetase 0.0163 0.0202 0.1279
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0067 0.0049 0.0049
Schistosoma mansoni z-protein (S1r protein) 0.0103 0.0106 0.0105
Echinococcus granulosus flap endonuclease 1 0.0188 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus granulosus voltage dependent calcium channel 0.0384 0.0555 0.0555
Trypanosoma cruzi trypanothione reductase, putative 0.1023 0.1574 0.2684
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0051 0.0024 0.0057
Mycobacterium ulcerans beta-lactamase 0.029 0.0404 0.1036
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0056 0.0031 0.0076
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Schistosoma mansoni patched 1 0.0042 0.0009 0.0008
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0428 0.0624 0.1528
Brugia malayi Nuclear hormone receptor-like 1 0.0102 0.0105 0.0163
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0061 0.0076
Brugia malayi ecdysone receptor 0.0048 0.0019 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0583 0.0872 0.0872
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Schistosoma mansoni hypothetical protein 0.0169 0.0212 0.0212
Toxoplasma gondii thioredoxin reductase 0.1023 0.1574 0.3154
Brugia malayi Calcium binding EGF domain containing protein 0.0115 0.0125 0.0194
Trypanosoma brucei PAB1-binding protein , putative 0.0155 0.0189 0.0322
Echinococcus multilocularis dna polymerase kappa 0.0179 0.0227 0.0227
Schistosoma mansoni cpg binding protein 0.0063 0.0043 0.0043
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0384 0.0555 0.0555
Trypanosoma brucei hypothetical protein, conserved 0.3713 0.5863 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0009 0.0017
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0044 0.0012 0.002
Echinococcus granulosus steroid dehydrogenase 0.0122 0.0137 0.0137
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0054 0.0028 0.0028
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0103 0.0107 0.0273
Plasmodium falciparum exonuclease I, putative 0.0038 0.0003 0.0017
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0051 0.0024 0.0046
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0121 0.0135 0.0135
Brugia malayi hypothetical protein 0.0054 0.0028 0.0043
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0094 0.0092 0.0225
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0218 0.029 0.0709
Mycobacterium ulcerans short-chain dehydrogenase 0.0122 0.0137 0.0351
Mycobacterium ulcerans hypothetical protein 0.0218 0.029 0.0742
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0102 0.0105 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Echinococcus multilocularis chromobox protein 1 0.0914 0.14 0.14
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0064 0.0044 0.0107
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0153 0.0186 0.0186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0163 0.0202 0.0251
Entamoeba histolytica Flap nuclease, putative 0.0188 0.0242 0.0297
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0163 0.0202 0.0251
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0067 0.0049 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0061 0.0076
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0094 0.0092 0.0092
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0168 0.0287
Echinococcus granulosus Mastin 0.0065 0.0046 0.0046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0071 0.0055 0.0085
Onchocerca volvulus 0.0052 0.0025 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0016 0.0019
Onchocerca volvulus Peroxidase homolog 0.0065 0.0045 0.0061
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Brugia malayi regulator of G-protein signaling egl-10 0.0103 0.0106 0.0164
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0355 0.0508 0.1302
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0117 0.0129 0.022
Echinococcus granulosus expressed conserved protein 0.0091 0.0088 0.0088
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0051 0.0024 0.0057
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0064 0.0044 0.0112
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0274
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0044 0.0012 0.002
Echinococcus multilocularis Regulator of G protein signaling 20 0.0103 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0044 0.0068
Schistosoma mansoni zinc finger protein 0.0048 0.0019 0.0018
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0355 0.0508 0.8104
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0051 0.0024 0.0025
Giardia lamblia NADH oxidase lateral transfer candidate 0.0355 0.0508 0.0631
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0122 0.0137 0.017
Onchocerca volvulus 0.0064 0.0044 0.006
Mycobacterium ulcerans ketoacyl reductase 0.0122 0.0137 0.0351
Trypanosoma cruzi NADH dehydrogenase, putative 0.0094 0.0092 0.0157
Entamoeba histolytica thioredoxin reductase, putative 0.0094 0.0092 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Onchocerca volvulus 0.029 0.0404 0.0553
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0064 0.0044 0.0107
Trichomonas vaginalis flap endonuclease-1, putative 0.0038 0.0003 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0239 0.0239
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0094 0.0092 0.0584
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0239 0.0239
Onchocerca volvulus 0.0065 0.0046 0.0062
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0044 0.0107
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0139 0.0139
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0094 0.0092 0.0114
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Plasmodium falciparum steroid dehydrogenase, putative 0.0122 0.0137 0.0869
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0137 0.0233
Onchocerca volvulus 0.0204 0.0267 0.0365
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0137 0.0335
Trichomonas vaginalis glutathione reductase, putative 0.0355 0.0508 0.0631
Brugia malayi nuclear receptor RXR 0.0054 0.0028 0.0043
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0122 0.0137 0.0233
Trypanosoma cruzi hypothetical protein, conserved 0.029 0.0404 0.0689
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0051 0.0024 0.0046
Plasmodium vivax hypothetical protein, conserved 0.015 0.0181 0.1146
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.015 0.0181 0.018
Trypanosoma cruzi cysteine peptidase, putative 0.0263 0.0361 0.0615
Toxoplasma gondii PAN domain-containing protein 0.0204 0.0267 0.0534
Schistosoma mansoni carbonyl reductase 0.0122 0.0137 0.0137
Entamoeba histolytica disulphide oxidoreductase, putative 0.0094 0.0092 0.0111
Brugia malayi jmjC domain containing protein 0.0992 0.1524 0.2376
Echinococcus multilocularis PHD finger protein rhinoceros 0.0267 0.0368 0.0368
Leishmania major 4-coumarate:coa ligase-like protein 0.0218 0.029 0.0493
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Schistosoma mansoni notch 0.0052 0.0025 0.0025
Onchocerca volvulus 0.0204 0.0267 0.0365
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0103 0.0106 0.0106
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0209
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0054 0.0054
Echinococcus granulosus FTZ F1 alpha 0.0102 0.0105 0.0105
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0164 0.0164
Brugia malayi Thioredoxin reductase 0.1023 0.1574 0.2454
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0072 0.0057 0.0088
Trichomonas vaginalis D-aminoacylase, putative 0.029 0.0404 0.0502
Loa Loa (eye worm) hypothetical protein 0.0583 0.0872 0.1359
Echinococcus multilocularis chromobox protein 1 0.0914 0.14 0.14
Schistosoma mansoni hypothetical protein 0.0853 0.1303 0.1302
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.029 0.0404 0.063
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0097 0.0117
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Brugia malayi hypothetical protein 0.0048 0.0019 0.0029
Brugia malayi glucose-6-phosphate dehydrogenase 0.0194 0.0251 0.0391
Schistosoma mansoni jumonji/arid domain-containing protein 0.0443 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0159 0.0196 0.0305
Loa Loa (eye worm) nuclear hormone receptor 0.0048 0.0019 0.0029
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Leishmania major hypothetical protein, conserved 0.0122 0.0137 0.0233
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0009 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Schistosoma mansoni sulfide quinone reductase 0.0094 0.0092 0.0092
Leishmania major hypothetical protein, conserved 0.0038 0.0003 0.0005
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0044 0.0075
Toxoplasma gondii phosphomannose isomerase type I protein 0.0103 0.0107 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0102 0.0105 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Brugia malayi beta-lactamase family protein 0.029 0.0404 0.063
Schistosoma mansoni peroxidasin 0.0065 0.0045 0.0045
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0051 0.0024 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0106 0.0131
Mycobacterium ulcerans dehydrogenase 0.0122 0.0137 0.0351
Echinococcus multilocularis cathepsin L cysteine protease 0.0069 0.0052 0.0052
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0122 0.0137 0.0233
Plasmodium vivax vivapain-2 0.0069 0.0052 0.0329
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.2392 0.3756 0.3756
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0088
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0085 0.0144
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.2595 0.408 1
Brugia malayi hypothetical protein 0.0103 0.0106 0.0164
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0051 0.0024 0.0059
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0122 0.0137 0.0335
Onchocerca volvulus 0.0148 0.0177 0.0242
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0038 0.0003 0.0005
Loa Loa (eye worm) DEAH box polypeptide 35 0.0159 0.0196 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Schistosoma mansoni alpha-glucosidase 0.029 0.0404 0.0404
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0044 0.0075
Brugia malayi Peroxidasin 0.0065 0.0045 0.007
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0069 0.0052 0.0052
Mycobacterium tuberculosis Possible oxidoreductase 0.0122 0.0137 0.0335
Entamoeba histolytica short chain dehydrogenase family protein 0.0122 0.0137 0.0167
Mycobacterium ulcerans short-chain type oxidoreductase 0.0122 0.0137 0.0351
Onchocerca volvulus 0.0204 0.0267 0.0365
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Onchocerca volvulus Cathepsin L homolog 0.0069 0.0052 0.0071
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0188 0.0242 0.0412
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1071 0.1649 0.1649
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0103 0.0106 0.0164
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0094 0.0092 0.1139
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Schistosoma mansoni ran 0.0043 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.004 0.0006 0.0006
Mycobacterium leprae Probable oxidoreductase 0.0122 0.0137 0.0335
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0103 0.0106 0.0106
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0287
Echinococcus granulosus regulator of G protein signaling 3 0.0103 0.0106 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0031 0.0052
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0094 0.0092 0.0114
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Trichomonas vaginalis set domain proteins, putative 0.4618 0.7306 0.9087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.0105 0.0105
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0484 0.0714 0.1112
Echinococcus granulosus WW domain containing oxidoreductase 0.0122 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.0051 0.0024 0.0023
Onchocerca volvulus 0.0122 0.0137 0.0187
Mycobacterium tuberculosis Putative ferredoxin reductase 0.2335 0.3665 0.8982
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0049 0.006
Echinococcus multilocularis exonuclease 1 0.0038 0.0003 0.0003
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0384 0.0555 0.0555
Schistosoma mansoni regulator of G protein signaling 0.0103 0.0106 0.0105
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0102 0.0105 0.0104
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.0239 0.0372
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0051 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0117 0.0129 0.0201
Brugia malayi Heterochromatin protein 1 0.0914 0.14 0.2182
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0045 0.007
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0045 0.0061
Trichomonas vaginalis penicillin-binding protein, putative 0.029 0.0404 0.0502
Loa Loa (eye worm) helicase 0.015 0.0181 0.0281
Entamoeba histolytica acyl-CoA synthetase, putative 0.0218 0.029 0.0356
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0194 0.0251 0.0428
Brugia malayi Trypsin-like protease protein 5 0.0065 0.0046 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0028 0.0043
Schistosoma mansoni carbonyl reductase 0.0122 0.0137 0.0137
Trypanosoma cruzi hypothetical protein, conserved 0.3713 0.5863 1
Echinococcus multilocularis protein jagged 1 0.0052 0.0025 0.0025
Toxoplasma gondii aldehyde dehydrogenase 0.0928 0.1422 0.2849
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0051 0.0024 0.0039
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0046
Brugia malayi hypothetical protein 0.0155 0.0189 0.0295
Brugia malayi nuclear hormone receptor family member nhr-6 0.0048 0.0019 0.0029
Schistosoma mansoni hypothetical protein 0.0061 0.004 0.0039
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0355 0.0508 0.0508
Plasmodium vivax vivapain-2 0.0069 0.0052 0.0329
Loa Loa (eye worm) PAN domain-containing protein 0.0204 0.0267 0.0416
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0051 0.0024 0.0039
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0051 0.0024 0.0024
Echinococcus granulosus slit 2 protein 0.0052 0.0025 0.0025
Echinococcus multilocularis protein dispatched 1 0.0048 0.0018 0.0018
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus granulosus lysosomal alpha glucosidase 0.0337 0.0479 0.0479
Leishmania major hypothetical protein, conserved 0.0094 0.0092 0.0157
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0051 0.0024 0.0024
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0038 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.029 0.0404 0.063
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0051 0.0024 0.0059
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0142 0.0168 0.0287
Plasmodium vivax hypothetical protein, conserved 0.0122 0.0137 0.0869
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Mycobacterium ulcerans dehydrogenase 0.0094 0.0092 0.0236
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0402 0.0583 0.0908
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0051 0.0024 0.0059
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.015 0.0181 0.0361
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0122 0.0137 0.0335
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0094 0.0092 0.0143
Brugia malayi hypothetical protein 0.007 0.0054 0.0083
Giardia lamblia Hypothetical protein 0.0122 0.0137 0.017
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0094 0.0092 0.0225
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0234 0.0315 0.0537
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0384 0.0555 0.0555
Brugia malayi Calcium binding EGF domain containing protein 0.0052 0.0025 0.0039
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0122 0.0137 0.0335
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0103 0.0107 0.0166
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0011 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0016 0.0019
Entamoeba histolytica deoxycytidyl transferase, putative 0.0179 0.0227 0.0279
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0054 0.0028 0.0028
Brugia malayi jmjC domain containing protein 0.0117 0.0129 0.0201
Loa Loa (eye worm) PAN domain-containing protein 0.0204 0.0267 0.0416
Plasmodium vivax DNA repair protein RAD2, putative 0.0038 0.0003 0.0017
Leishmania major 3-keto-dihydrosphingosine reductase 0.0122 0.0137 0.0233
Brugia malayi dehydrogenases, short chain protein 9 0.0122 0.0137 0.0213
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0103 0.0107 0.0166
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0384 0.0555 0.0865
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0094 0.0092 0.1139
Echinococcus granulosus carbonyl reductase 1 0.0122 0.0137 0.0137
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Echinococcus granulosus geminin 0.0169 0.0212 0.0212
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0168 0.0287
Onchocerca volvulus 0.1526 0.2375 0.325
Schistosoma mansoni peroxidasin 0.0065 0.0045 0.0045
Echinococcus granulosus raf serine:threonine protein kinase 0.0044 0.0012 0.0012
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0122 0.0137 0.0213
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0045 0.007
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0122 0.0137 0.0167
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.029 0.0404 0.0404
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0194 0.0251 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Mycobacterium tuberculosis Probable esterase LipL 0.029 0.0404 0.099
Giardia lamblia hypothetical protein 0.0038 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0046 0.0071
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0094 0.0092 0.0184
Brugia malayi nuclear hormone receptor 0.0048 0.0019 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Schistosoma mansoni survival motor neuron protein 0.0148 0.0177 0.0177
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.2335 0.3665 0.8982
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Leishmania major hypothetical protein, conserved 0.0155 0.0189 0.0322
Plasmodium vivax hypothetical protein, conserved 0.0267 0.0368 0.2339
Trichomonas vaginalis chromobox protein, putative 0.0914 0.14 0.1741
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0355 0.0508 0.3223
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0122 0.0137 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0156 0.0191 0.0237
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0022 0.0033
Leishmania major hypothetical protein, conserved 0.0094 0.0092 0.0157
Giardia lamblia Short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0064 0.0044 0.0112
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0093 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0049 0.0076
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0003 0.0003
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0122 0.0137 0.0335
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0038 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Trypanosoma brucei unspecified product 0.0179 0.0227 0.0387
Echinococcus multilocularis peroxidasin 0.0065 0.0045 0.0045
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0064 0.0044 0.0068
Brugia malayi Cathepsin L-like precursor 0.0069 0.0052 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0049 0.0083
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0051 0.0024 0.0039
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0044 0.0075
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0428 0.0624 0.16
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Plasmodium falciparum LCCL domain-containing protein 0.0582 0.0869 0.5522
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0239 0.0239
Loa Loa (eye worm) XPG I-region family protein 0.0038 0.0003 0.0004
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0122 0.0137 0.0233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Echinococcus granulosus PHD finger protein rhinoceros 0.0267 0.0368 0.0368
Loa Loa (eye worm) jmjC domain-containing protein 0.0117 0.0129 0.0201
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Plasmodium falciparum heterochromatin protein 1 0.015 0.0181 0.1146
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0122 0.0137 0.0167
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Leishmania major DNA polymerase eta, putative 0.0055 0.0031 0.0052
Brugia malayi chromobox protein homolog 3 0.0512 0.0759 0.1183
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0188 0.0459
Mycobacterium ulcerans hypothetical protein 0.0428 0.0624 0.16
Echinococcus granulosus nuclear receptor nhr 48 0.0048 0.0019 0.0019
Toxoplasma gondii microneme protein MIC17C 0.0204 0.0267 0.0534
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0094 0.0092 0.0111
Entamoeba histolytica hypothetical protein 0.015 0.0181 0.0221
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0188 0.0459
Schistosoma mansoni glutamate synthase 0.0094 0.0092 0.0092
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0122 0.0137 0.0351
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0019 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0011 0.0019
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0067 0.0049 0.0083
Leishmania major short chain dehydrogenase, putative 0.0122 0.0137 0.0233
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0088
Echinococcus multilocularis dnaJ subfamily C 6 0.0061 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Echinococcus multilocularis regulator of G protein signaling 0.0103 0.0106 0.0106
Schistosoma mansoni chromobox protein 0.015 0.0181 0.018
Entamoeba histolytica hypothetical protein 0.015 0.0181 0.0221
Onchocerca volvulus 0.0204 0.0267 0.0365
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0189 0.0322
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0274
Entamoeba histolytica hypothetical protein, conserved 0.0122 0.0137 0.0167
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0064 0.0044 0.0088
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0052 0.0088
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0122 0.0137 0.0869
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0102 0.0105 0.0163
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0046 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Leishmania major cathepsin L-like protease 0.0263 0.0361 0.0615
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0011 0.0011
Trypanosoma brucei short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Echinococcus granulosus exonuclease 1 0.0038 0.0003 0.0003
Echinococcus multilocularis expressed protein 0.191 0.2989 0.2989
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Schistosoma mansoni nuclear receptor 0.0048 0.0019 0.0018
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1071 0.1649 0.1649
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0122 0.0137 0.0187
Trypanosoma brucei trypanothione reductase 0.1023 0.1574 0.2684
Echinococcus multilocularis cysteine protease 0.0069 0.0052 0.0052
Trypanosoma cruzi hypothetical protein 0.0072 0.0057 0.0096
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0122 0.0137 0.0137
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0384 0.0555 0.0555
Trichomonas vaginalis chromobox protein, putative 0.015 0.0181 0.0224
Entamoeba histolytica hypothetical protein 0.007 0.0054 0.0063
Echinococcus granulosus laminin 0.0115 0.0125 0.0125
Onchocerca volvulus 0.0069 0.0052 0.0071
Loa Loa (eye worm) glutathione reductase 0.1023 0.1574 0.2454
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0093 0.009 0.0153
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0064 0.0044 0.0112
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0087 0.0081 0.0163
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0065 0.0046 0.0045
Echinococcus multilocularis neurogenic locus protein delta 0.0052 0.0025 0.0025
Toxoplasma gondii microneme protein MIC17A 0.0204 0.0267 0.0534
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0429 0.0626 0.1255
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0094 0.0092 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0055 0.0031 0.0047
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0054 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Onchocerca volvulus Peroxidase homolog 0.0065 0.0045 0.0061
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.2481 0.3898 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0049 0.002 0.0025
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0094 0.0092 0.0157
Echinococcus multilocularis Chromo domain 0.015 0.0181 0.0181
Brugia malayi Trypsin family protein 0.0065 0.0046 0.0071
Schistosoma mansoni hypothetical protein 0.004 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.0105 0.0105
Schistosoma mansoni notch 0.0052 0.0025 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0928 0.1422 0.3647
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0105 0.0163
Plasmodium vivax importin-beta 2, putative 0.009 0.0085 0.0537
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0927 0.1421 0.2215
Trichomonas vaginalis conserved hypothetical protein 0.0363 0.0521 0.0647
Brugia malayi cathepsin L-like precursor 0.0046 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0168 0.0168
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0094 0.0092 0.0157
Trypanosoma brucei NADH dehydrogenase 0.0094 0.0092 0.0157
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0094 0.0092 0.0157
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0051 0.0024 0.0057
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0355 0.0508 0.0508
Trypanosoma brucei short-chain dehydrogenase, putative 0.0122 0.0137 0.0233
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0137 0.0233
Onchocerca volvulus Bile acid receptor homolog 0.0102 0.0105 0.0143
Entamoeba histolytica hypothetical protein, conserved 0.0122 0.0137 0.0167
Onchocerca volvulus 0.0204 0.0267 0.0365
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0051 0.0024 0.0036
Leishmania major short chain dehydrogenase/reductase, putative 0.0122 0.0137 0.0233
Echinococcus multilocularis carbonyl reductase 1 0.0122 0.0137 0.0137
Echinococcus granulosus jumonji domain containing protein 0.0372 0.0535 0.0535
Echinococcus granulosus Regulator of G protein signaling 20 0.0103 0.0106 0.0106
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Echinococcus granulosus tar DNA binding protein 0.0065 0.0046 0.0046
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0115 0.0125 0.0194
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Onchocerca volvulus Neurogenic locus notch homolog 0.0052 0.0025 0.0034
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0064 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.015 0.0181 0.0281
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0194 0.0251 0.4008
Schistosoma mansoni mannose-6-phosphate isomerase 0.0103 0.0107 0.0106
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0303 0.0425 0.0661
Echinococcus granulosus retinol dehydrogenase 11 0.0122 0.0137 0.0137
Trichomonas vaginalis chromobox protein, putative 0.015 0.0181 0.0224
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0928 0.1422 0.1422
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0122 0.0137 0.0167
Schistosoma mansoni exonuclease 0.0038 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0102 0.0105 0.0163
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0274
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0069 0.0052 0.0329
Brugia malayi TAR-binding protein 0.0065 0.0046 0.0071
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.0227 0.0387
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0064 0.0044 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.0105 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.1071 0.1649 0.1649
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.015 0.0181 0.0221
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0287
Brugia malayi hypothetical protein 0.0048 0.0019 0.0029
Echinococcus granulosus retinol dehydrogenase 11 0.0122 0.0137 0.0137
Echinococcus granulosus ecdysone induced protein 78C 0.0102 0.0105 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0139 0.0236
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Loa Loa (eye worm) hypothetical protein 0.0065 0.0046 0.0071
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0337 0.0479 0.0746
Trypanosoma cruzi DNA polymerase eta, putative 0.0179 0.0227 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0031 0.0052
Mycobacterium tuberculosis Probable reductase 0.2335 0.3665 0.8982
Echinococcus granulosus Tolloid protein 1 0.0115 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.029 0.0404 0.063
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0122 0.0137 0.017
Trypanosoma brucei DNA damage repair protein, putative 0.0055 0.0031 0.0052
Toxoplasma gondii PHD-finger domain-containing protein 0.0267 0.0368 0.0738
Brugia malayi hypothetical protein 0.015 0.0181 0.0281
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0234 0.0315 0.0537
Brugia malayi hypothetical protein 0.0122 0.0137 0.0213
Echinococcus granulosus protein jagged 1 0.0052 0.0025 0.0025
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0045 0.007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0102 0.0105 0.0105
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0044 0.0107
Echinococcus granulosus regulator of G protein signaling 3 0.0103 0.0106 0.0106
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0044 0.0044
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0338 0.0481 0.0481
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0019 0.0029
Brugia malayi Protein cec-1. 0.015 0.0181 0.0281
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0046 0.0046
Echinococcus multilocularis steroid dehydrogenase 0.0122 0.0137 0.0137
Echinococcus granulosus axis inhibition protein axin 0.0103 0.0106 0.0106
Plasmodium vivax DNA repair protein REV1, putative 0.0055 0.0031 0.0192
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0051 0.0024 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0164
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0117 0.0129 0.022
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0011 0.0017
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.0024 0.0023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0117 0.0129 0.0258
Trichomonas vaginalis penicillin-binding protein, putative 0.029 0.0404 0.0502
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0551 0.0821 0.1124
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.0169 0.0168
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0094 0.0092 0.0114
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0046 0.0071
Brugia malayi steroid hormone receptor 0.0102 0.0105 0.0163
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.0061 0.0076
Mycobacterium ulcerans ferredoxin reductase 0.0094 0.0092 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Leishmania major acetyl-CoA synthetase, putative 0.0064 0.0044 0.0075
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0051 0.0024 0.0032
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0189 0.1201
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0261 0.0358 0.0557
Mycobacterium ulcerans ketoacyl reductase 0.0122 0.0137 0.0351
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0211 0.0279 0.0558
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0928 0.1422 0.1422
Echinococcus granulosus lysine specific demethylase 6a 0.0117 0.0129 0.0129
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0093 0.009 0.009
Brugia malayi Pip kinase protein 2 0.0338 0.0481 0.0749
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Mycobacterium tuberculosis Possible oxidoreductase 0.0122 0.0137 0.0335
Echinococcus multilocularis thioredoxin glutathione reductase 0.1031 0.1586 0.1586
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0122 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0512 0.0759 0.0944
Onchocerca volvulus 0.029 0.0404 0.0553
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Echinococcus multilocularis dnaJ subfamily B 0.0853 0.1303 0.1303
Echinococcus granulosus peroxidasin 0.0065 0.0045 0.0045
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.0058 0.0098
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0022 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.4058 0.6413 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.015 0.0181 0.0181
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Brugia malayi CHE-14 protein 0.0042 0.0009 0.0013
Plasmodium vivax acyl-CoA synthetase, putative 0.0163 0.0202 0.1279
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0168 0.0209
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0046 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.5078 0.804 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0103 0.0106 0.0105
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0122 0.0137 0.017
Loa Loa (eye worm) hypothetical protein 0.0071 0.0055 0.0085
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0188 0.0242 0.0412
Onchocerca volvulus 0.0582 0.0869 0.119
Echinococcus granulosus voltage dependent calcium channel 0.008 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0164
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0115 0.0125 0.0194
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0512 0.0759 0.1183
Mycobacterium ulcerans short-chain dehydrogenase 0.0122 0.0137 0.0351
Onchocerca volvulus 0.0204 0.0267 0.0365
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0122 0.0137 0.0137
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0211 0.0279 0.0346
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0093 0.009 0.0153
Schistosoma mansoni axis inhibition protein axin 0.0103 0.0106 0.0105
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0051 0.0024 0.0024
Echinococcus granulosus survival motor neuron protein 1 0.0724 0.1096 0.1096
Treponema pallidum thioredoxin reductase (trxB) 0.0094 0.0092 0.0086
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0162 0.0162
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Echinococcus granulosus cathepsin l1 0.0069 0.0052 0.0052
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Brugia malayi hypothetical protein 0.0582 0.0869 0.1355
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0051 0.0024 0.0029
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0049 0.0083
Trypanosoma brucei polo-like protein kinase 0.1071 0.1649 0.2813
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0188 0.0242 0.0412
Brugia malayi Trypsin family protein 0.0065 0.0046 0.0071
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0046 0.0071
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0122 0.0137 0.0167
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0583 0.0872 0.0872
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0384 0.0555 0.0555
Onchocerca volvulus 0.0065 0.0046 0.0062
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1023 0.1574 0.3857
Trichomonas vaginalis glutamate synthase, putative 0.0094 0.0092 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0061 0.0076
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0051 0.0024 0.0024
Leishmania major cathepsin L-like protease 0.0069 0.0052 0.0088
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Brugia malayi SET domain containing protein 0.0172 0.0217 0.0338
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.1526 0.2375 0.3703
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0122 0.0137 0.0233
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0355 0.0508 0.0865
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0094 0.0092 0.0584
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0122 0.0137 0.0335
Mycobacterium ulcerans DNA polymerase IV 0.0179 0.0227 0.0582
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0583 0.0872 0.0872
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0064 0.0045 0.0075
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Loa Loa (eye worm) X11 protein 0.0276 0.0382 0.0595
Treponema pallidum fructose-bisphosphate aldolase 0.5078 0.804 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0189 0.1201
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0106 0.0131
Brugia malayi serine/threonine-protein kinase plk-2 0.1071 0.1649 0.2572
Plasmodium falciparum JmjC domain-containing protein, putative 0.0117 0.0129 0.0819
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0355 0.0508 0.0865
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Schistosoma mansoni terminal deoxycytidyl transferase 0.0179 0.0227 0.0227
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0117 0.0129 0.0258
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Echinococcus multilocularis neurogenic locus protein delta 0.0052 0.0025 0.0025
Schistosoma mansoni cathepsin F (C01 family) 0.0069 0.0052 0.0052
Echinococcus granulosus chromobox protein 1 0.0914 0.14 0.14
Loa Loa (eye worm) hypothetical protein 0.0065 0.0045 0.007
Echinococcus multilocularis sodium channel protein 0.0163 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.029 0.0404 0.063
Echinococcus multilocularis dna polymerase eta 0.0179 0.0227 0.0227
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0044 0.0112
Echinococcus granulosus JmjC domain containing protein 4 0.0117 0.0129 0.0129
Brugia malayi ImpB/MucB/SamB family protein 0.0179 0.0227 0.0354
Onchocerca volvulus 0.0122 0.0137 0.0187
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.105 0.1616 0.1616
Brugia malayi hypothetical protein 0.0103 0.0106 0.0164
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.0061 0.0061
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Brugia malayi jmjC domain containing protein 0.0117 0.0129 0.0201
Toxoplasma gondii PHD-finger domain-containing protein 0.0087 0.0081 0.0163
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0044 0.0075
Schistosoma mansoni hypothetical protein 0.0148 0.0177 0.0177
Toxoplasma gondii PAN domain-containing protein 0.3165 0.4989 1
Plasmodium falciparum ferrodoxin reductase-like protein 0.0094 0.0092 0.0584
Schistosoma mansoni ran 0.0043 0.0011 0.0011
Brugia malayi GCC2 and GCC3 family protein 0.0052 0.0025 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Loa Loa (eye worm) PXA domain-containing protein 0.0103 0.0106 0.0164
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Trypanosoma brucei oxidoreductase-like protein 0.0122 0.0137 0.0233
Giardia lamblia DINP protein human, muc B family 0.0179 0.0227 0.0282
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0094 0.0092 0.0143
Leishmania major DNA polymerase eta, putative 0.0179 0.0227 0.0387
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0106 0.0111 0.0173
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0142 0.0168 0.0337
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0051 0.0024 0.0039
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0102 0.0105 0.0105
Echinococcus multilocularis citrate lyase subunit beta protein 0.0428 0.0624 0.0624
Plasmodium vivax exonuclease I, putative 0.0038 0.0003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0164
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0047 0.0017 0.0018
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0012 0.0018
Onchocerca volvulus 0.0204 0.0267 0.0365
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0061 0.0072
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0103 0.0106 0.0105
Schistosoma mansoni cpg binding protein 0.006 0.0038 0.0037
Loa Loa (eye worm) PAN domain-containing protein 0.0204 0.0267 0.0416
Trypanosoma brucei unspecified product 0.0123 0.0139 0.0236
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0004
Brugia malayi ImpB/MucB/SamB family protein 0.0179 0.0227 0.0354
Echinococcus multilocularis phd:f box containing protein 0.0117 0.0129 0.0129
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.024 0.0325 0.0553
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0384 0.0555 0.0555
Trypanosoma cruzi short chain dehydrogenase, putative 0.0122 0.0137 0.0233
Leishmania major 4-coumarate:coa ligase-like protein 0.0218 0.029 0.0493
Toxoplasma gondii hypothetical protein 0.0071 0.0055 0.0109
Schistosoma mansoni phd/f-box containing protein 0.0117 0.0129 0.0129
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0428 0.0624 0.1064
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0051 0.0024 0.0059
Schistosoma mansoni DNA polymerase eta 0.0179 0.0227 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.1071 0.1649 0.2051
Echinococcus multilocularis Mastin 0.0065 0.0046 0.0046
Plasmodium falciparum glutathione reductase 0.0355 0.0508 0.3223
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0142 0.0168 0.0287
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0064 0.0044 0.0088
Brugia malayi Trypsin family protein 0.0065 0.0046 0.0071
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0142 0.0168 0.0287
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0428 0.0624 0.16
Echinococcus granulosus dnaJ subfamily B 0.0853 0.1303 0.1303
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.029 0.0404 0.0404
Leishmania major cathepsin L-like protease 0.0263 0.0361 0.0615
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0137 0.0335
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0051 0.0024 0.0059
Echinococcus granulosus mannose 6 phosphate isomerase 0.0103 0.0107 0.0107
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Mycobacterium tuberculosis Probable lipase LipE 0.029 0.0404 0.099
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.5078 0.804 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0163 0.0202 0.0251
Trypanosoma cruzi polo-like protein kinase, putative 0.1071 0.1649 0.2813
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0094 0.0092 0.0111
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0122 0.0137 0.0233
Entamoeba histolytica hypothetical protein 0.007 0.0054 0.0063
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0055 0.0031 0.0061
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0428 0.0624 0.1064
Trypanosoma cruzi hypothetical protein, conserved 0.029 0.0404 0.0689
Entamoeba histolytica hypothetical protein 0.007 0.0054 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0211 0.0279 0.1769
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0093 0.009 0.014
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Mycobacterium tuberculosis Probable lipase LipD 0.029 0.0404 0.099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0512 0.0759 0.0944
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.2335 0.3665 0.8982
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0179 0.0227 0.0227
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0051 0.0024 0.0024
Echinococcus multilocularis nuclear receptor nhr 48 0.0048 0.0019 0.0019
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0055 0.0031 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Loa Loa (eye worm) flap endonuclease-1 0.0188 0.0242 0.0377
Echinococcus multilocularis raf serine:threonine protein kinase 0.0044 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0384 0.0555 0.0865
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Leishmania major quinonoid dihydropteridine reductase 0.0122 0.0137 0.0233
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0072 0.0057 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0048 0.0019 0.0029
Trichomonas vaginalis flap endonuclease-1, putative 0.0038 0.0003 0.0003
Brugia malayi glutamate synthase 0.0094 0.0092 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Schistosoma mansoni rab6-interacting 0.0582 0.0869 0.0869
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Loa Loa (eye worm) Notch2 0.0052 0.0025 0.0039
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0122 0.0137 0.0137
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.2595 0.408 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0928 0.1422 0.3484
Giardia lamblia Thioredoxin reductase 0.0094 0.0092 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0061 0.0076
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0122 0.0137 0.017
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0355 0.0508 0.0865
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0098 0.0098 0.0153
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0094 0.0092 0.0092
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0069 0.0052 0.0081
Loa Loa (eye worm) programmed cell death 8 0.0094 0.0092 0.0143
Onchocerca volvulus 0.0303 0.0425 0.0581
Echinococcus multilocularis Tolloid protein 1 0.0115 0.0125 0.0125
Onchocerca volvulus 0.015 0.0181 0.0247
Trypanosoma cruzi cysteine peptidase, putative 0.0263 0.0361 0.0615
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0067 0.0049 0.0057
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.105 0.1616 0.1615
Brugia malayi EGF-like domain containing protein 0.0052 0.0025 0.0039
Brugia malayi PAN domain containing protein 0.0204 0.0267 0.0416
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Onchocerca volvulus 0.0204 0.0267 0.0365
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0051 0.0024 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Schistosoma mansoni hypothetical protein 0.0052 0.0025 0.0025
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0067 0.0049 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0263 0.0361 0.0615
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0048 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0122 0.0137 0.0213
Brugia malayi Regulator of G protein signaling domain containing protein 0.0103 0.0106 0.0164
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0188 0.0459
Schistosoma mansoni laminin gamma-3 chain 0.0052 0.0025 0.0025
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0011 0.0069
Echinococcus multilocularis ecdysone induced protein 78C 0.0102 0.0105 0.0105
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0956 0.1467 0.2287
Brugia malayi DnaJ domain containing protein 0.0061 0.004 0.0061
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0157 0.0192 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0583 0.0872 0.0872
Loa Loa (eye worm) hypothetical protein 0.0103 0.0106 0.0164
Echinococcus multilocularis protein jagged 1 0.0052 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0132 0.0153 0.0239
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0052 0.0025 0.0034
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0179 0.0227 0.0227
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0122 0.0137 0.0167
Brugia malayi nuclear hormone receptor family member odr-7 0.0048 0.0019 0.0029
Echinococcus granulosus peregrin 0.0271 0.0374 0.0374
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0429 0.0626 0.1255
Schistosoma mansoni alpha glucosidase 0.0075 0.0061 0.0061
Brugia malayi PHD-finger family protein 0.0091 0.0087 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Brugia malayi AMP-binding enzyme family protein 0.0218 0.029 0.0451
Schistosoma mansoni hypothetical protein 0.0267 0.0368 0.0368
Mycobacterium ulcerans lipase LipD 0.029 0.0404 0.1036
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Brugia malayi nuclear receptor RXR 0.0048 0.0019 0.0029
Loa Loa (eye worm) DR-78 0.0048 0.0019 0.0029
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0102 0.0105 0.0105
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0094 0.0092 0.0092
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0094 0.0092 0.0092
Brugia malayi hypothetical protein 0.0132 0.0153 0.0239
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0051 0.0024 0.0039
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0065 0.0046 0.0046
Echinococcus granulosus regulator of G protein signaling 7 0.0103 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Echinococcus granulosus cathepsin L cysteine proteinase 0.0069 0.0052 0.0052
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0085 0.0144
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0064 0.0044 0.0075
Toxoplasma gondii microneme protein MIC17B 0.0204 0.0267 0.0534
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0094 0.0092 0.0092
Echinococcus multilocularis carbonyl reductase 1 0.0122 0.0137 0.0137
Toxoplasma gondii oxidoreductase, putative 0.0122 0.0137 0.0274
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.2595 0.408 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0239 0.0239
Leishmania major NADH dehydrogenase, putative 0.0094 0.0092 0.0157
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0103 0.0107 0.0166
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0122 0.0137 0.0274
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0061 0.0076
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0142 0.0168 0.2404
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0102 0.0105 0.0163
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.2335 0.3665 0.8982
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0038 0.0003 0.0003
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0051 0.0024 0.0039
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0051 0.0024 0.0057
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0044 0.0075
Loa Loa (eye worm) trypsin family protein 0.0065 0.0046 0.0071
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0122 0.0137 0.0137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.0105 0.0163
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0355 0.0508 0.0865
Brugia malayi Cathepsin L-like precursor 0.0069 0.0052 0.0081
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0067 0.0049 0.0049
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.105 0.1616 0.1616
Onchocerca volvulus 0.0069 0.0052 0.0071
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0019 0.0019
Loa Loa (eye worm) oxidoreductase 0.0064 0.0044 0.0068
Plasmodium vivax steroid dehydrogenase, putative 0.0122 0.0137 0.0869
Leishmania major short chain dehydrogenase, putative 0.0122 0.0137 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0181 0.0224
Schistosoma mansoni retinoic acid receptor RXR 0.0102 0.0105 0.0104
Echinococcus multilocularis expressed conserved protein 0.0091 0.0088 0.0088
Schistosoma mansoni cpg binding protein 0.0063 0.0043 0.0043
Onchocerca volvulus 0.4618 0.7306 1
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0051 0.0024 0.0059
Mycobacterium ulcerans ketoacyl reductase 0.0122 0.0137 0.0351
Entamoeba histolytica hypothetical protein 0.0122 0.0137 0.0167
Brugia malayi Trypsin family protein 0.0065 0.0046 0.0071
Schistosoma mansoni microtubule-associated protein tau 0.6308 1 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0428 0.0624 0.1064
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0148 0.0179 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0363 0.0521 0.0647
Echinococcus multilocularis importin subunit beta 1 0.009 0.0085 0.0085
Onchocerca volvulus 0.0102 0.0105 0.0143
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0355 0.0508 0.1302
Trypanosoma brucei DNA repair protein RAD2, putative 0.0038 0.0003 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0097 0.0097
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0335
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0102 0.0105 0.0105
Echinococcus multilocularis geminin 0.0169 0.0212 0.0212
Schistosoma mansoni chromobox protein 0.0914 0.14 0.1399
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0094 0.0092 0.0584
Trichomonas vaginalis flap endonuclease-1, putative 0.0038 0.0003 0.0003
Brugia malayi MH2 domain containing protein 0.0479 0.0706 0.11
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0058 0.0072
Schistosoma mansoni retinal dehydrogenase 0.0122 0.0137 0.0137
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0103 0.0107 0.0675
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0106 0.0131
Mycobacterium ulcerans hypothetical protein 0.0065 0.0046 0.0117
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0093 0.009 0.0153
Trypanosoma brucei hypothetical protein, conserved 0.029 0.0404 0.0689
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0064 0.0044 0.0068
Trichomonas vaginalis chromobox protein, putative 0.0914 0.14 0.1741
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0061 0.0104
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0194 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0204 0.0267 0.0416
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0115 0.0125 0.0194
Schistosoma mansoni steroid dehydrogenase 0.0122 0.0137 0.0137
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Entamoeba histolytica serine/threonine protein kinase, putative 0.1071 0.1649 0.2048
Plasmodium vivax acetyl-CoA synthetase, putative 0.0064 0.0044 0.0278
Loa Loa (eye worm) hypothetical protein 0.0338 0.0481 0.0749
Echinococcus granulosus carbonyl reductase 1 0.0122 0.0137 0.0137
Loa Loa (eye worm) oxidoreductase 0.0122 0.0137 0.0213
Loa Loa (eye worm) hypothetical protein 0.0724 0.1096 0.1709
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0179 0.0227 0.0227
Trypanosoma brucei glucosidase, putative 0.0075 0.0061 0.0104
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Echinococcus granulosus lipoxygenase domain containing protein 0.0582 0.0869 0.0869
Brugia malayi hypothetical protein 0.0065 0.0046 0.0071
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0355 0.0508 0.0865
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0061 0.0076
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Brugia malayi RNA, U transporter 1 0.0255 0.0348 0.0542
Entamoeba histolytica hypothetical protein 0.0429 0.0626 0.0776
Plasmodium falciparum importin beta, putative 0.009 0.0085 0.0537
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0064 0.0044 0.0068
Trypanosoma cruzi trypanothione reductase, putative 0.0355 0.0508 0.0865
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0194 0.0251 0.0428
Brugia malayi Regulator of G protein signaling domain containing protein 0.0103 0.0106 0.0164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0069 0.0052 0.0064
Toxoplasma gondii oxidoreductase, putative 0.0122 0.0137 0.0274
Schistosoma mansoni notch 0.0052 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0069 0.0052 0.0064
Echinococcus granulosus jumonji domain containing 1A 0.0117 0.0129 0.0129
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0051 0.0024 0.0059
Loa Loa (eye worm) raf kinase 0.0043 0.001 0.0015
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0094 0.0092 0.0143
Echinococcus granulosus oxidoreductase 0.0122 0.0137 0.0137
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0055 0.0031 0.0061
Brugia malayi Steroid receptor seven-up type 2 0.0102 0.0105 0.0163
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0384 0.0555 0.0555
Onchocerca volvulus 0.0065 0.0046 0.0062
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0218 0.029 0.0742
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.105 0.1616 0.3959
Schistosoma mansoni glutamate synthase 0.0094 0.0092 0.0092
Echinococcus multilocularis lysosomal alpha glucosidase 0.0337 0.0479 0.0479
Echinococcus multilocularis voltage dependent calcium channel 0.0384 0.0555 0.0555
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0103 0.0107 0.0132
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0094 0.0092 0.0157
Toxoplasma gondii hypothetical protein 0.0204 0.0267 0.0534
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Toxoplasma gondii calcium binding egf domain-containing protein 0.0115 0.0125 0.0249
Onchocerca volvulus 0.0065 0.0046 0.0062
Echinococcus multilocularis flap endonuclease GEN 1 0.0038 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0051 0.0024 0.0023
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0093 0.009 0.0112
Loa Loa (eye worm) hypothetical protein 0.0052 0.0025 0.0039
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0122 0.0137 0.0213
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0122 0.0137 0.0187
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Echinococcus multilocularis axis inhibition protein axin 0.0103 0.0106 0.0106
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0094 0.0092 0.0236
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0094 0.0092 0.0114
Onchocerca volvulus 0.0402 0.0583 0.0797
Echinococcus multilocularis JmjC domain containing protein 4 0.0117 0.0129 0.0129
Echinococcus granulosus beta LACTamase domain containing family member 0.029 0.0404 0.0404
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0094 0.0092 0.0092
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0064 0.0044 0.0107
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0009 0.0009
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0003 0.0000051859
Mycobacterium tuberculosis Conserved hypothetical protein 0.0179 0.0227 0.0556
Brugia malayi regulator of G-protein signaling rgs-7 0.0103 0.0106 0.0164
Loa Loa (eye worm) PHD-finger family protein 0.0267 0.0368 0.0574
Loa Loa (eye worm) PAN domain-containing protein 0.0204 0.0267 0.0416
Trichomonas vaginalis CAMK family protein kinase 0.053 0.0787 0.0979
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0072 0.0057 0.0067
Brugia malayi M-phase phosphoprotein, mpp8 0.015 0.0181 0.0281
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0122 0.0137 0.0213
Schistosoma mansoni cercarial elastase (S01 family) 0.0065 0.0046 0.0045
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.0227 0.0387
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0429 0.0626 0.3978
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0194 0.0251 0.0284
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0102 0.0105 0.0163
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0122 0.0137 0.0351
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0094 0.0092 0.0114
Schistosoma mansoni acetyl-CoA synthetase 0.0064 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0102 0.0105 0.0163
Echinococcus multilocularis laminin 0.0115 0.0125 0.0125
Schistosoma mansoni phosphatidylserine receptor 0.0117 0.0129 0.0129
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0045 0.0061
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0051 0.0024 0.0059
Echinococcus granulosus notch 0.0052 0.0025 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0122 0.0137 0.0137
Mycobacterium ulcerans short chain dehydrogenase 0.0122 0.0137 0.0351
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0142 0.0168 0.0181
Onchocerca volvulus Sepiapterin reductase homolog 0.0122 0.0137 0.0187
Leishmania major oxidoreductase-like protein 0.0122 0.0137 0.0233

Activities

Activity type Activity value Assay description Source Reference
IC50 (ADMET) = 73 nM Concentration required for 50% toxicity in metastatic lung carcinoma (MV522) cells. ChEMBL. 11000013

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.