Detailed information for compound 592063

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 508.614 | Formula: C30H32N6O2
  • H donors: 3 H acceptors: 3 LogP: 5.64 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(c1cccc(c1)Nc1nccc(n1)Nc1ccc(cc1)Oc1ccccc1)NCCN1CCCCC1
  • InChi: 1S/C30H32N6O2/c37-29(31-18-21-36-19-5-2-6-20-36)23-8-7-9-25(22-23)34-30-32-17-16-28(35-30)33-24-12-14-27(15-13-24)38-26-10-3-1-4-11-26/h1,3-4,7-17,22H,2,5-6,18-21H2,(H,31,37)(H2,32,33,34,35)
  • InChiKey: IOPAODNPPCBEKQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Plasmodium falciparum calcium-dependent protein kinase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Theileria parva calcium-dependent protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum Calcium-dependent protein kinase 2, related Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum ko:K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II, putative Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum calcium-dependent protein kinase 1 Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania mexicana protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium hominis CDPK2 Get druggable targets OG5_126600 All targets in OG5_126600
Theileria parva calmodulin-domain protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) CAMK/CAMK2 protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans Serine-threonine protein kinase similar to S. cerevisiae CMK2 (YOL016C) calcium/calmodulin-dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Babesia bovis calcium-dependent protein kinase 4 Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium berghei calcium-dependent protein kinase 4 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium vivax calcium-dependent protein kinase 4, putative Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis calcium dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum calcium-dependent protein kinase 5 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii calcium-dept. protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type II delta chain, putative Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii calcium-dependent protein kinase CDPK2A Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi Cam kinase protein 1 Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii calcium-dependent protein kinase CDPK3 Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium parvum calmodulin-domain protein kinase 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum calcium-dependent protein kinase 2 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium berghei calcium-dependent protein kinase 3 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus calcium dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium knowlesi calcium-dependent protein kinase 5, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum ko:K08794 calcium/calmodulin-dependent protein kinase I, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type II beta chain, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium berghei calcium-dependent protein kinase 1 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum calcium-dependent protein kinase 3 Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium berghei calcium-dependent protein kinase 5 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii Plasmodium falciparum CDPK2 protein Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium vivax calcium-dependent protein kinase 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum calcium-dependent protein kinase 4 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii calcium-dependent protein kinase-3 Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii calcium-dependent protein kinase CDPK2B Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum Calmodulin-like domain protein kinase isoenzyme gamma, related Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium knowlesi calcium-dependent protein kinase 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii calmodulin-domain protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium vivax calcium-dependent protein kinase 3, putative Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania donovani protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium knowlesi calcium-dependent protein kinase 3, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium vivax calcium-dependent protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans Serine-threonine protein kinase similar to S. cerevisiae CMK2 (YOL016C) calcium/calmodulin-dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium knowlesi calcium-dependent protein kinase 4, putative Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania infantum protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania major protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium hominis calcium-dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type II alpha chain, putative Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium hominis calmodulin-domain protein kinase 1 Get druggable targets OG5_126600 All targets in OG5_126600
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tissue type plasminogen activator 0.001 0 0.0001
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0024 0.0008 0.0018
Schistosoma mansoni methyl-cpg binding protein mbd 0.0013 0.0002 0.0006
Mycobacterium ulcerans pyruvate kinase 0.0024 0.0008 0.0017
Schistosoma mansoni neuropeptide F-like receptor 0.0702 0.0378 0.1274
Echinococcus multilocularis axis inhibition protein axin 0.0013 0.0002 0.0004
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0022 0.0047
Schistosoma mansoni SET domain protein 0.0015 0.0003 0.001
Mycobacterium ulcerans endonuclease IV 0.0051 0.0022 0.006
Echinococcus granulosus WW domain containing oxidoreductase 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.2518 0.1367 0.2989
Brugia malayi hypothetical protein 0.0013 0.0002 0.0002
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.0008 0.0007
Echinococcus granulosus liprin alpha 2 0.004 0.0016 0.0035
Echinococcus multilocularis liprin beta 1 0.004 0.0016 0.0039
Echinococcus granulosus ETS domain containing protein Elk 1 0.0013 0.0002 0.0003
Onchocerca volvulus 0.003 0.0011 0.0037
Loa Loa (eye worm) TK/ROR protein kinase 0.001 0 0.0001
Schistosoma mansoni lamin 0.0137 0.007 0.0234
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.5448 0.2964 0.6498
Onchocerca volvulus 0.0172 0.0089 0.0299
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.0053
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0702 0.0378 0.0828
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.008 0.0269
Brugia malayi hypothetical protein 0.0026 0.0009 0.0009
Mycobacterium ulcerans lipase LipD 0.0172 0.0089 0.0255
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Leishmania major short chain dehydrogenase, putative 0.0096 0.0047 0.0103
Schistosoma mansoni hypothetical protein 0.0237 0.0124 0.0418
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0237 0.0124 0.0295
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0009
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0022 0.0051
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0702 0.0378 0.0901
Plasmodium vivax cysteine repeat modular protein 1, putative 0.001 0 0.0048
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Onchocerca volvulus 0.0096 0.0047 0.0159
Trypanosoma cruzi protein kinase A regulatory subunit 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0172 0.0089 0.0299
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0702 0.0378 0.0901
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0014 0.0003 0.004
Loa Loa (eye worm) hypothetical protein 0.0081 0.0039 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0006 0.0098
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0019 0.0005 0.0011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.006 0.0028 0.0059
Brugia malayi latrophilin 2 splice variant baaae 0.0512 0.0274 0.0274
Onchocerca volvulus 0.0702 0.0378 0.1274
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus multilocularis regulator of G protein signaling 3 0.0013 0.0002 0.0004
Echinococcus multilocularis fmrfamide receptor 0.0702 0.0378 0.0901
Entamoeba histolytica hypothetical protein 0.0208 0.0108 0.1349
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0011 0.0001 0.0002
Mycobacterium tuberculosis Probable hydrolase 0.0172 0.0089 0.0256
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0143 0.0073 0.0245
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0229 0.012 0.0261
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Schistosoma mansoni hypothetical protein 0.0237 0.0124 0.0418
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0051 0.0022 0.006
Mycobacterium leprae Conserved hypothetical protein 0.0041 0.0017 0.1723
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0702 0.0378 0.1274
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0011 0.0182
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0021 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0032 0.0012 0.0026
Mycobacterium ulcerans 6-phosphofructokinase 0.0077 0.0037 0.0102
Plasmodium falciparum cGMP-dependent protein kinase 0.0015 0.0003 0.0548
Echinococcus multilocularis dnaJ subfamily C 6 0.0045 0.002 0.0046
Echinococcus granulosus inositol monophosphatase 1 0.006 0.0028 0.006
Leishmania major protein kinase, putative 0.0019 0.0005 0.001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0004 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0172 0.0089 0.0193
Mycobacterium ulcerans ketoacyl reductase 0.0096 0.0047 0.0133
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0008 0.0025
Brugia malayi nuclear receptor NHR-88 0.0049 0.0022 0.0022
Brugia malayi hypoxia-induced factor 1 0.0187 0.0097 0.0096
Plasmodium vivax SET domain protein, putative 0.0143 0.0073 0.82
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.001 0.0155
Leishmania major hypothetical protein, conserved 0.0096 0.0047 0.0103
Schistosoma mansoni ets 0.0013 0.0002 0.0005
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0018 0.0005 0.001
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0023 0.0007 0.0015
Onchocerca volvulus 0.0702 0.0378 0.1274
Schistosoma mansoni cellular tumor antigen P53 0.0026 0.0009 0.0029
Echinococcus granulosus neuropeptide receptor 0.0702 0.0378 0.0825
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0131
Echinococcus multilocularis neuropeptide receptor 0.0702 0.0378 0.0901
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0066 0.0031 0.0067
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) hypothetical protein 0.0074 0.0035 0.0077
Schistosoma mansoni carbonyl reductase 0.0096 0.0047 0.0159
Onchocerca volvulus 0.0058 0.0026 0.0088
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.003 0.0011 0.1921
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) TAR-binding protein 0.027 0.0142 0.0311
Brugia malayi Neurabin protein 1 0.004 0.0016 0.0016
Onchocerca volvulus 0.0023 0.0008 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0038 0.0126
Echinococcus multilocularis muscleblind protein 0.0634 0.0341 0.0812
Brugia malayi G protein-coupled receptor 0.0702 0.0378 0.0377
Trypanosoma cruzi cAMP response protein 1 0.0014 0.0003 0.0005
Brugia malayi Cam kinase protein 1 0.0019 0.0005 0.0005
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0014 0.0003 0.0006
Trypanosoma brucei short-chain dehydrogenase, putative 0.0096 0.0047 0.0101
Mycobacterium ulcerans short-chain type oxidoreductase 0.0096 0.0047 0.0133
Schistosoma mansoni neuropeptide F-like receptor 0.0702 0.0378 0.1274
Echinococcus multilocularis conserved hypothetical protein 0.0096 0.0047 0.0112
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0003 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0008 0.0025
Brugia malayi Serotonin receptor 0.0702 0.0378 0.0377
Echinococcus multilocularis pyruvate kinase 0.0024 0.0008 0.0019
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Schistosoma mansoni opsin-like receptor 0.0702 0.0378 0.1274
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0031
Echinococcus multilocularis G protein coupled receptor 139 0.0702 0.0378 0.0901
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0103 0.0051 0.0111
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0037 0.0602
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0054 0.0024 0.2545
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0014 0.0003 0.0032
Onchocerca volvulus 0.0023 0.0008 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0031
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0051 0.0022 0.0022
Onchocerca volvulus 0.0096 0.0047 0.0159
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0008 0.0025
Schistosoma mansoni lipoxygenase 0.0295 0.0156 0.0525
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0028 0.001 0.0022
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0014 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0172 0.0089 0.0194
Loa Loa (eye worm) hypothetical protein 0.0055 0.0025 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.0043 0.0018 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Plasmodium vivax hypothetical protein, conserved 0.0172 0.0089 1
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) hypothetical protein 0.0034 0.0014 0.0029
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0108 0.0054 0.0116
Loa Loa (eye worm) hypothetical protein 0.0749 0.0403 0.0883
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Entamoeba histolytica hypothetical protein 0.0096 0.0047 0.0586
Echinococcus granulosus hypothetical protein 0.8402 0.4574 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0002 0.0004
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0702 0.0378 0.1274
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0096 0.0047 0.0577
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0039 0.8345
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0016 0.0003 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0022 0.0047
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.01 0.0049 0.0108
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0749 0.0403 0.0403
Schistosoma mansoni ets-related 0.0262 0.0138 0.0465
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0088 0.0043 0.0707
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0096 0.0047 0.0101
Schistosoma mansoni inositol monophosphatase 0.006 0.0028 0.0092
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Brugia malayi beta-lactamase family protein 0.0172 0.0089 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0002 0.0008
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0041 0.0017 0.0044
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0011 0.0022
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0004 0.06
Onchocerca volvulus 0.0026 0.0009 0.0029
Schistosoma mansoni carbonyl reductase 0.0096 0.0047 0.0159
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0012 0.0029
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0008 0.0016
Leishmania major pyruvate kinase 0.0024 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0024
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0017 0.0004 0.0009
Schistosoma mansoni ap endonuclease 0.0014 0.0003 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.2585 0.1404 0.3069
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0041 0.0017 0.0044
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Echinococcus granulosus beta LACTamase domain containing family member 0.0172 0.0089 0.0193
Echinococcus granulosus cpg binding protein 0.0115 0.0058 0.0125
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0096 0.0047 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0035
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0055 0.0156
Loa Loa (eye worm) hypothetical protein 0.8378 0.4561 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.0008 0.0016
Echinococcus multilocularis neuropeptides capa receptor 0.0702 0.0378 0.0901
Echinococcus granulosus Protein Wnt-111 0.0081 0.0039 0.0085
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0008 0.0131
Onchocerca volvulus 0.0045 0.0019 0.0064
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0702 0.0378 0.0901
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0014 0.0003 0.0002
Echinococcus multilocularis beta LACTamase domain containing family member 0.0172 0.0089 0.0211
Plasmodium vivax glutathione reductase, putative 0.0048 0.0021 0.239
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0014 0.0003 0.0002
Toxoplasma gondii cytochrome p450 superfamily protein 0.0041 0.0017 0.0208
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0013 0.0002 0.0006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0003 0.0005
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.001 0.0166
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0041 0.0017 0.0044
Schistosoma mansoni polycystin 1-related 0.0055 0.0025 0.0083
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0014 0.0003 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0028 0.001 0.0024
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.0062 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0055 0.0025 0.0083
Echinococcus multilocularis nibrin 0.003 0.0011 0.0026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0052 0.0023 0.0078
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0075 0.0036 0.0099
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0011 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0017
Schistosoma mansoni z-protein (S1r protein) 0.0018 0.0005 0.0015
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0004 0.0063
Brugia malayi tailless protein 0.0023 0.0008 0.0007
Loa Loa (eye worm) DnaJ domain-containing protein 0.0045 0.002 0.0042
Plasmodium falciparum pyruvate kinase 0.0024 0.0008 0.1609
Echinococcus multilocularis wingless type MMTV integration site family 0.0081 0.0039 0.0093
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0096 0.0047 0.0112
Schistosoma mansoni ets-related 0.0013 0.0002 0.0005
Brugia malayi hypothetical protein 0.0096 0.0047 0.0047
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0078 0.0038 0.0089
Echinococcus granulosus nibrin 0.003 0.0011 0.0024
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0006 0.0095
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.004 0.0017 0.0205
Treponema pallidum exodeoxyribonuclease (exoA) 0.0014 0.0003 0.0015
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0013 0.0002 0.0338
Toxoplasma gondii Alpha-galactosidase 0.0011 0.0001 0.0011
Brugia malayi hypothetical protein 0.0088 0.0043 0.0043
Echinococcus multilocularis pyruvate kinase 0.0012 0.0002 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0229 0.012 0.0261
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0002 0.0025
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis orexin receptor type 2 0.0702 0.0378 0.0901
Brugia malayi putative neuropeptide receptor NPR1 0.0702 0.0378 0.0377
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Trichomonas vaginalis protein kinase inhibitor, putative 0.0045 0.002 0.0321
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Echinococcus multilocularis g protein coupled receptor 0.0702 0.0378 0.0901
Loa Loa (eye worm) hypothetical protein 0.0058 0.0026 0.0057
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0013
Giardia lamblia Reductase, putative 0.0096 0.0047 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0031
Echinococcus granulosus axis inhibition protein axin 0.0013 0.0002 0.0004
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0096 0.0047 0.0133
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.002 0.0006 0.0014
Echinococcus multilocularis steroid dehydrogenase 0.0096 0.0047 0.0112
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0006 0.0686
Echinococcus multilocularis nervana 2 0.0011 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0005
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0006 0.0019
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0003 0.0005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0135 0.0069 0.015
Mycobacterium tuberculosis Conserved protein 0.0172 0.0089 0.0256
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0229 0.012 0.012
Leishmania major ATP-dependent phosphofructokinase 0.0077 0.0037 0.0079
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0003 0.0032
Echinococcus granulosus intermediate filament protein 0.0137 0.007 0.0152
Loa Loa (eye worm) hypothetical protein 0.1333 0.0721 0.1581
Brugia malayi follicle stimulating hormone receptor 0.0869 0.0468 0.0468
Plasmodium falciparum steroid dehydrogenase, putative 0.0096 0.0047 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.0105 0.023
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0003 0.0053
Entamoeba histolytica hypothetical protein 0.0013 0.0002 0.0023
Loa Loa (eye worm) transcription factor SMAD2 0.0189 0.0098 0.0214
Echinococcus granulosus Ankyrin 0.0017 0.0004 0.0009
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0022 0.0073
Onchocerca volvulus Pyruvate kinase homolog 0.0024 0.0008 0.0026
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.0003 0.0005
Echinococcus granulosus pyruvate kinase 0.0012 0.0002 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0041 0.0017 0.0044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Toxoplasma gondii LsmAD domain-containing protein 0.0082 0.0039 0.0483
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0039 0.8345
Loa Loa (eye worm) doublecortin family protein 0.0055 0.0025 0.0054
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0096 0.0047 0.5209
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Echinococcus multilocularis expressed protein 0.0024 0.0008 0.0018
Schistosoma mansoni netrin receptor unc5 0.001 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0011 0.0182
Loa Loa (eye worm) RecQ helicase 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0702 0.0378 0.1274
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0027 0.001 0.0019
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.1135 0.0613 0.1344
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0022 0.0022
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0013 0.0002 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0011
Entamoeba histolytica hypothetical protein 0.0103 0.0051 0.0632
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.1135 0.0613 0.1344
Echinococcus granulosus carbonyl reductase 1 0.0096 0.0047 0.0103
Entamoeba histolytica hypothetical protein 0.0303 0.016 0.1992
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0096 0.0047 0.0103
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0009 0.0019
Plasmodium falciparum glutathione reductase 0.0048 0.0021 0.4443
Echinococcus multilocularis bloom syndrome protein 0.0014 0.0003 0.0005
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0004 0.0063
Plasmodium vivax ataxin-2 like protein, putative 0.0082 0.0039 0.4448
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.0039
Schistosoma mansoni neuropeptide f receptor 76f 0.0702 0.0378 0.1274
Echinococcus multilocularis protein Wnt 1 0.0081 0.0039 0.0093
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0004 0.0004
Entamoeba histolytica PH domain containing protein kinase, putative 0.0013 0.0002 0.002
Echinococcus granulosus poly (ADP ribose) polymerase 0.0303 0.016 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0011
Schistosoma mansoni ankyrin 23/unc44 0.001 0.0001 0.0001
Schistosoma mansoni myst-related protein 0.0014 0.0003 0.0008
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0008 0.0017
Brugia malayi glutathione reductase 0.0048 0.0021 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0043 0.0018 0.0047
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0022 0.0047
Onchocerca volvulus 0.0702 0.0378 0.1274
Schistosoma mansoni topbp1 0.003 0.0011 0.0037
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.0003 0.0004
Brugia malayi Ets-domain containing protein 0.0086 0.0042 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.0008 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Brugia malayi G-protein coupled receptor 0.0702 0.0378 0.0377
Schistosoma mansoni tar DNA-binding protein 0.027 0.0142 0.0479
Brugia malayi MH2 domain containing protein 0.0013 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.2585 0.1404 0.3077
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0021 0.0006 0.1032
Brugia malayi regulator of G-protein signaling rgs-7 0.0013 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0006 0.0014
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0.001 0.0023
Leishmania major hypothetical protein, conserved 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0041 0.0017 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0131
Brugia malayi Dehydrogenases, short chain protein 30 0.0096 0.0047 0.0047
Brugia malayi wnt family protein 0.0081 0.0039 0.0039
Trypanosoma cruzi FHA domain containing protein, putative 0.003 0.0011 0.0024
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0096 0.0047 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0047 0.0133
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0008 0.0007
Brugia malayi hypothetical protein 0.0103 0.0051 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0041 0.0017 0.0044
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0004 0.0446
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0003 0.004
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0035
Trypanosoma brucei short-chain dehydrogenase, putative 0.0096 0.0047 0.0101
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0077 0.0037 0.0079
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0012
Schistosoma mansoni loxhd1 0.0055 0.0025 0.0083
Echinococcus multilocularis pyruvate kinase 0.0012 0.0002 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0022 0.0022
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0005 0.0011
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0052 0.0023 0.005
Echinococcus granulosus WGR domain containing protein 0.0606 0.0325 0.071
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0022 0.0051
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3551 0.193 0.4605
Brugia malayi Ets-domain containing protein 0.0086 0.0042 0.0042
Leishmania major protein kinase A regulatory subunit, putative 0.0014 0.0003 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0011
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.006 0.0028 0.0337
Trichomonas vaginalis penicillin-binding protein, putative 0.0172 0.0089 0.1465
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0003 0.0032
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0016 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0006 0.0098
Schistosoma mansoni methyl-cpg binding protein mbd 0.0013 0.0002 0.0006
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0096 0.0047 0.0101
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0003 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Schistosoma mansoni bromodomain containing protein 0.0054 0.0025 0.0082
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0096 0.0047 0.0103
Brugia malayi Pyruvate kinase, muscle isozyme 0.0024 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0041 0.0017 0.0044
Brugia malayi Retinol dehydrogenase 12 0.0096 0.0047 0.0047
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0096 0.0047 0.0103
Brugia malayi Dehydrogenases, short chain protein 2 0.0096 0.0047 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0233 0.0122 0.0411
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0702 0.0378 0.0901
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0009 0.003
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0003 0.0041
Trypanosoma brucei oxidoreductase-like protein 0.0096 0.0047 0.0101
Giardia lamblia Pyruvate kinase 0.0012 0.0002 0.0077
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0016 0.0034
Trichomonas vaginalis rotamase, putative 0.0024 0.0008 0.0123
Leishmania major hypothetical protein, conserved 0.0012 0.0001 0.0002
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0702 0.0378 0.0825
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0003 0.0053
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0043 0.0018 0.0039
Echinococcus multilocularis pyruvate kinase 0.0024 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus multilocularis steroid dehydrogenase 0.0096 0.0047 0.0112
Schistosoma mansoni neuropeptide receptor 0.0702 0.0378 0.1274
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0237 0.0124 0.0124
Brugia malayi Regulator of G protein signaling domain containing protein 0.0013 0.0002 0.0002
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0096 0.0047 0.0103
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0014 0.0003 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0055 0.0156
Schistosoma mansoni hypothetical protein 0.0512 0.0274 0.0924
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Echinococcus multilocularis ets variant gene 4 0.0013 0.0002 0.0004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0089 0.0211
Trypanosoma brucei glucosidase, putative 0.0038 0.0016 0.0032
Schistosoma mansoni coup transcription factor 0.0049 0.0022 0.0073
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Schistosoma mansoni elf1 0.0013 0.0002 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0004 0.0296
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0016 0.0037
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.003 0.0011 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Schistosoma mansoni gabp alpha 0.0086 0.0042 0.0141
Leishmania major hypothetical protein, conserved 0.0096 0.0047 0.0103
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0096 0.0047 0.0133
Echinococcus multilocularis protein Wnt 2 0.0081 0.0039 0.0093
Loa Loa (eye worm) hypothetical protein 0.1333 0.0721 0.1581
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0022 0.0073
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0008 0.0131
Onchocerca volvulus 0.0702 0.0378 0.1274
Onchocerca volvulus 0.0096 0.0047 0.0159
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Mycobacterium ulcerans hypothetical protein 0.0014 0.0003 0.0002
Plasmodium vivax pyruvate kinase 2, putative 0.0012 0.0002 0.0175
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0255
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0004 0.0007
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0022 0.0022
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0096 0.0047 0.0133
Schistosoma mansoni amine GPCR 0.0702 0.0378 0.1274
Mycobacterium ulcerans oxidoreductase 0.0096 0.0047 0.0133
Echinococcus granulosus retinol dehydrogenase 11 0.0096 0.0047 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0003 0.0053
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0041 0.0017 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0022 0.0022
Brugia malayi small heat shock protein 0.0366 0.0195 0.0194
Mycobacterium ulcerans carveol-like dehydrogenase 0.0096 0.0047 0.0133
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0008 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Loa Loa (eye worm) TYRA-2 protein 0.0702 0.0378 0.0828
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.1135 0.0613 0.1463
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0003 0.0053
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0039 0.0016 0.0035
Schistosoma mansoni hypothetical protein 0.0037 0.0015 0.0049
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0634 0.0341 0.0746
Schistosoma mansoni 60S ribosomal protein L21 0.0015 0.0003 0.0009
Brugia malayi DKFZp564C0469 protein 0.003 0.0011 0.0011
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0702 0.0378 0.0828
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.008 0.0269
Plasmodium falciparum pyruvate kinase 2 0.0012 0.0002 0.0242
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0702 0.0378 0.1274
Schistosoma mansoni hypothetical protein 0.004 0.0016 0.0055
Echinococcus multilocularis retinol dehydrogenase 11 0.0096 0.0047 0.0112
Echinococcus multilocularis Glutaredoxin protein 5 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0094 0.0046 0.0101
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0702 0.0378 0.0828
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0002 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0022 0.0047
Schistosoma mansoni hypothetical protein 0.0045 0.002 0.0065
Echinococcus granulosus methyl CpG binding domain protein 2 0.0013 0.0002 0.0004
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0081 0.0039 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0007 0.0089
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0108 0.0054 0.0117
Brugia malayi Pre-SET motif family protein 0.0143 0.0073 0.0073
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0096 0.0047 0.0047
Brugia malayi Bromodomain containing protein 0.0029 0.0011 0.0011
Schistosoma mansoni single-minded 0.006 0.0028 0.0093
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.001 0.0155
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Onchocerca volvulus Tankyrase homolog 0.0545 0.0292 0.0985
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0022 0.0073
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0577
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0015 0.0035
Brugia malayi ecdysteroid receptor 0.0049 0.0022 0.0022
Onchocerca volvulus 0.004 0.0016 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.003 0.0064
Brugia malayi topoisomerase 0.003 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0006 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0031
Trypanosoma cruzi Protein kinase B 0.0013 0.0002 0.0003
Echinococcus multilocularis inositol monophosphatase 1 0.006 0.0028 0.0065
Onchocerca volvulus 0.0702 0.0378 0.1274
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Toxoplasma gondii peptidylprolyl isomerase 0.0023 0.0007 0.009
Brugia malayi Pyruvate kinase, M2 isozyme 0.0024 0.0008 0.0008
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0089 0.0211
Brugia malayi nuclear receptor RXR 0.0026 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Echinococcus granulosus Protein Wnt-5 0.0081 0.0039 0.0085
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0013 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0702 0.0378 0.0825
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0019 0.0005 0.0011
Schistosoma mansoni myosin xvIII 0.0702 0.0378 0.1274
Trypanosoma brucei poly(adp-ribose) polymerase 0.1135 0.0613 0.1343
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0002 0.0001
Echinococcus multilocularis pyruvate kinase 0.0019 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0081 0.0039 0.0085
Plasmodium falciparum thioredoxin reductase 0.0048 0.0021 0.4443
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0006 0.0019
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0003 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0022 0.0022
Echinococcus granulosus serotonin receptor 0.0702 0.0378 0.0825
Brugia malayi hypothetical protein 0.0026 0.0009 0.0009
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0051 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Echinococcus granulosus pyruvate kinase 0.0012 0.0002 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0022 0.0047
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0074 0.0035 0.0076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.012 0.0403
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0052 0.0023 0.0054
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0011 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0023
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0077 0.0037 0.0102
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0041 0.0017 0.0044
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0028 0.001 0.001
Schistosoma mansoni biogenic amine receptor 0.0702 0.0378 0.1274
Brugia malayi MH1 domain containing protein 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0041 0.0017 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0255
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0096 0.0047 0.0159
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0702 0.0378 0.0377
Echinococcus granulosus tm gpcr rhodopsin 0.0702 0.0378 0.0825
Schistosoma mansoni hypothetical protein 0.0237 0.0124 0.0418
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0003 0.0006
Trypanosoma brucei protein kinase, putative 0.0027 0.001 0.0019
Mycobacterium ulcerans hypothetical protein 0.0121 0.0061 0.0172
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0041 0.0017 0.0036
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.5209
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0702 0.0378 0.0825
Echinococcus granulosus survival motor neuron protein 1 0.0933 0.0504 0.11
Brugia malayi Egg laying defective protein 4 0.0015 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0933 0.0504 0.1104
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0022 0.0073
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0007
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0012 0.0029
Echinococcus granulosus poly (ADP ribose) polymerase 0.0303 0.016 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0034
Treponema pallidum NADH oxidase 0.0017 0.0004 0.0404
Onchocerca volvulus 0.001 0 0.0001
Leishmania major protein kinase, putative 0.0016 0.0004 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0131
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.0039
Loa Loa (eye worm) Wnt2 protein 0.0081 0.0039 0.0085
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.001 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Mycobacterium ulcerans esterase/lipase LipP 0.0172 0.0089 0.0255
Trypanosoma cruzi C-8 sterol isomerase, putative 0.8378 0.4561 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.0003 0.0005
Schistosoma mansoni cytochrome P450 0.0041 0.0017 0.0057
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0023
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0021 0.0046
Schistosoma mansoni tar DNA-binding protein 0.027 0.0142 0.0479
Schistosoma mansoni hypothetical protein 0.0702 0.0378 0.1274
Loa Loa (eye worm) isocitrate dehydrogenase 0.0013 0.0002 0.0004
Echinococcus granulosus ETS transcription factor Elf 1 0.0013 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0137 0.007 0.0152
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0011
Trichomonas vaginalis hypothetical protein 0.0013 0.0002 0.0029
Brugia malayi hypothetical protein 0.0203 0.0105 0.0105
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0096 0.0047 0.0133
Trypanosoma cruzi cAMP binding protein, putative 0.0014 0.0003 0.0005
Schistosoma mansoni axis inhibition protein axin 0.0013 0.0002 0.0006
Brugia malayi beta-lactamase 0.0172 0.0089 0.0088
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0013 0.0002 0.0003
Trypanosoma brucei protein kinase A regulatory subunit 0.0014 0.0003 0.0004
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Schistosoma mansoni smad 0.0013 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0011 0.0182
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Echinococcus granulosus neuropeptide Y receptor 0.0702 0.0378 0.0825
Mycobacterium ulcerans hypothetical protein 0.0014 0.0003 0.0002
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0003 0.0032
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0011 0.0023
Brugia malayi 6-phosphofructokinase 0.0077 0.0037 0.0036
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0004 0.0694
Trichomonas vaginalis myo inositol monophosphatase, putative 0.006 0.0028 0.0453
Schistosoma mansoni pyruvate kinase 0.0012 0.0002 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0096 0.0047 0.0101
Brugia malayi Inositol-1 0.006 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0109 0.0054 0.0118
Brugia malayi hypothetical protein 0.0819 0.0441 0.0441
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0027 0.001 0.0117
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0003 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0055 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0172 0.0089 0.0193
Entamoeba histolytica hypothetical protein 0.0014 0.0003 0.0029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0229 0.012 0.0262
Echinococcus granulosus Protein Wnt-11b 0.0081 0.0039 0.0085
Brugia malayi Wnt-2 protein precursor 0.0081 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Loa Loa (eye worm) histone methyltransferase 0.0038 0.0016 0.0034
Schistosoma mansoni nuclear receptor 0.0023 0.0008 0.0025
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0702 0.0378 0.0377
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0014 0.0003 0.0002
Echinococcus multilocularis isocitrate dehydrogenase 0.0013 0.0002 0.0004
Plasmodium falciparum calcium-dependent protein kinase 5 0.0019 0.0005 0.0999
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0028 0.001 0.0034
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.1511 0.0818 1
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0014 0.0003 0.0006
Entamoeba histolytica hypothetical protein 0.0208 0.0108 0.1349
Loa Loa (eye worm) hypothetical protein 0.0055 0.0025 0.0054
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0003 0.0006
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0022 0.0073
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0006 0.1211
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0027 0.001 0.002
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0006 0.0075
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0047 0.0103
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0041 0.0017 0.0036
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0014 0.0003 0.0008
Leishmania major hypothetical protein, conserved 0.0082 0.0039 0.0086
Echinococcus multilocularis ETS transcription factor Elf 2 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) hypothetical protein 0.0192 0.0099 0.0217
Loa Loa (eye worm) hypothetical protein 0.0634 0.0341 0.0746
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0096 0.0047 0.0047
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0096 0.0047 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0005 0.001
Brugia malayi hypothetical protein 0.0023 0.0008 0.0007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.0008 0.0007
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0013 0.0002 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0047 0.0133
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0014 0.0003 0.0005
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0019 0.0005 0.0063
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Toxoplasma gondii AGC kinase 0.0017 0.0004 0.0053
Leishmania major mitochondrial DNA polymerase beta 0.0229 0.012 0.0261
Onchocerca volvulus Netrin receptor homolog 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0096 0.0047 0.0133
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0096 0.0047 0.0103
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0096 0.0047 0.0159
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Onchocerca volvulus 0.0055 0.0025 0.0083
Echinococcus granulosus ETS transcription factor Elf 5 0.0013 0.0002 0.0003
Mycobacterium ulcerans short-chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0016 0.0003 0.0007
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0022 0.0073
Schistosoma mansoni hypothetical protein 0.004 0.0016 0.0055
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.004 0.0016 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0041 0.0017 0.0044
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0013 0.0002 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0172 0.0089 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0013
Schistosoma mansoni intermediate filament proteins 0.0137 0.007 0.0234
Echinococcus multilocularis Ankyrin 0.0017 0.0004 0.001
Echinococcus granulosus sex peptide receptor 0.0702 0.0378 0.0825
Loa Loa (eye worm) hypothetical protein 0.0058 0.0026 0.0057
Schistosoma mansoni tar DNA-binding protein 0.027 0.0142 0.0479
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1333 0.0721 0.2432
Entamoeba histolytica protein kinase, putative 0.0019 0.0005 0.0061
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0024 0.0008 0.0007
Schistosoma mansoni vesicular acetylcholine transporter 0.5448 0.2964 1
Brugia malayi Fli-1 protein 0.0262 0.0138 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0041 0.0017 0.0044
Loa Loa (eye worm) fli-1 protein 0.0262 0.0138 0.0302
Entamoeba histolytica hypothetical protein 0.0103 0.0051 0.0632
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0052 0.0023 0.0078
Loa Loa (eye worm) intermediate filament protein 0.0137 0.007 0.0152
Echinococcus granulosus lipoxygenase domain containing protein 0.0055 0.0025 0.0054
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0041 0.0017 0.0044
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0096 0.0047 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0019 0.0005 0.0081
Loa Loa (eye worm) hypothetical protein 0.0192 0.0099 0.0217
Mycobacterium tuberculosis Conserved protein 0.0014 0.0003 0.0002
Echinococcus granulosus Glutaredoxin protein 5 0.0011 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0013 0.0002 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0172 0.0089 0.0256
Entamoeba histolytica protein kinase 2, putative 0.0012 0.0001 0.0013
Echinococcus granulosus axis inhibition protein axin 0.0013 0.0002 0.0004
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0012
Echinococcus multilocularis smad 0.0013 0.0002 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0577
Leishmania major oxidoreductase-like protein 0.0096 0.0047 0.0103
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0014 0.0003 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0003 0.0009
Leishmania major short chain dehydrogenase-like protein 0.0096 0.0047 0.0103
Schistosoma mansoni neuropeptide receptor 0.0702 0.0378 0.1274
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0013 0.0002 0.0006
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.1481 0.0802 0.1913
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0002 0.0004
Echinococcus multilocularis neuropeptide receptor A26 0.0942 0.0508 0.1212
Schistosoma mansoni aryl hydrocarbon receptor 0.006 0.0028 0.0093
Entamoeba histolytica phosphofructokinase, putative 0.0077 0.0037 0.0453
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0016 0.0033
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0022 0.0073
Loa Loa (eye worm) MH2 domain-containing protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) bromodomain containing protein 0.0013 0.0002 0.0004
Trypanosoma cruzi short chain dehydrogenase, putative 0.0096 0.0047 0.0103
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0096 0.0047 0.0103
Brugia malayi dehydrogenases, short chain protein 2 0.0096 0.0047 0.0047
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0014 0.0003 0.0008
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0019 0.0005 0.0011
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0014 0.0003 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0008 0.0025
Onchocerca volvulus 0.0096 0.0047 0.0159
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus granulosus lamin 0.0137 0.007 0.0152
Brugia malayi Melatonin receptor type 1A 0.0702 0.0378 0.0377
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0006
Echinococcus multilocularis transient receptor potential cation channel 0.0096 0.0047 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Schistosoma mansoni serine/threonine-protein kinase 0.0013 0.0002 0.0005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0027 0.001 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) PHD-finger family protein 0.0016 0.0003 0.0007
Mycobacterium ulcerans short-chain dehydrogenase 0.0096 0.0047 0.0133
Plasmodium vivax steroid dehydrogenase, putative 0.0096 0.0047 0.532
Schistosoma mansoni lip-related protein (liprin) alpha 0.004 0.0016 0.0055
Echinococcus multilocularis mothers against decapentaplegic 5 0.0013 0.0002 0.0004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.027 0.0142 0.0311
Brugia malayi Cytochrome P450 family protein 0.0075 0.0036 0.0035
Echinococcus multilocularis WNT 0.0081 0.0039 0.0093
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0096 0.0047 0.0112
Loa Loa (eye worm) hypoxia-induced factor 1 0.0187 0.0097 0.0212
Treponema pallidum DNA ligase (lig) 0.003 0.0011 0.2535
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0004 0.0049
Echinococcus multilocularis biogenic amine (5HT) receptor 0.2518 0.1367 0.3262
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0003
Echinococcus granulosus neuropeptide receptor A26 0.0942 0.0508 0.1111
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.001 0.0155
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0041 0.0017 0.0044
Schistosoma mansoni cpg binding protein 0.0115 0.0058 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0123
Echinococcus multilocularis calcium dependent protein kinase 0.0018 0.0005 0.0011
Onchocerca volvulus 0.0143 0.0073 0.0245
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0014 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0135 0.0068 0.0149
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0077 0.0037 0.0078
Onchocerca volvulus Pyruvate kinase homolog 0.0024 0.0008 0.0026
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0002 0.0001
Schistosoma mansoni rab6-interacting 0.0055 0.0025 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0022 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0047 0.0103
Brugia malayi ERG2 and Sigma1 receptor like protein 0.8378 0.4561 0.456
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0035
Brugia malayi Wnt-4 protein precursor 0.0081 0.0039 0.0039
Echinococcus granulosus pyruvate kinase 0.0012 0.0002 0.0003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0211 0.011 0.134
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0041 0.0017 0.0035
Trypanosoma brucei trypanothione reductase 0.0048 0.0021 0.0044
Echinococcus multilocularis Regulator of G protein signaling 20 0.0013 0.0002 0.0004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0006 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0041 0.0017 0.0044
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0022 0.0073
Mycobacterium ulcerans ketoacyl reductase 0.0096 0.0047 0.0133
Brugia malayi isocitrate dehydrogenase 0.0013 0.0002 0.0002
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0096 0.0047 0.0586
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0096 0.0047 0.0577
Echinococcus multilocularis retinol dehydrogenase 11 0.0096 0.0047 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0047 0.0103
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0022 0.0051
Loa Loa (eye worm) hypothetical protein 0.0512 0.0274 0.06
Loa Loa (eye worm) hypothetical protein 0.0081 0.0039 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.0039
Brugia malayi hypothetical protein 0.004 0.0016 0.0016
Brugia malayi Cytochrome P450 family protein 0.0075 0.0036 0.0035
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0702 0.0378 0.0828
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0702 0.0378 0.1274
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0011 0.0024
Mycobacterium tuberculosis Probable lipase LipE 0.0172 0.0089 0.0256
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0016 0.0003 0.0396
Giardia lamblia Hypothetical protein 0.0096 0.0047 1
Leishmania major protein kinase, putative 0.0031 0.0012 0.0024
Trypanosoma brucei pyruvate kinase 1, putative 0.0024 0.0008 0.0015
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0096 0.0047 0.0103
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0003 0.0297
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0037 0.0602
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0027 0.001 0.002
Mycobacterium leprae Probable lipase LipE 0.0172 0.0089 1
Echinococcus granulosus Polycystic kidney disease protein 0.0055 0.0025 0.0054
Schistosoma mansoni amine GPCR 0.0702 0.0378 0.1274
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0016 0.0003 0.0007
Brugia malayi Cyclic-nucleotide gated cation channel 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0702 0.0378 0.1274
Echinococcus multilocularis axis inhibition protein axin 0.0013 0.0002 0.0004
Brugia malayi steroid hormone receptor 0.0049 0.0022 0.0022
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0014 0.0003 0.0301
Mycobacterium leprae Probable pyruvate kinase PykA 0.0024 0.0008 0.068
Echinococcus granulosus g-protein coupled receptor 0.0702 0.0378 0.0825
Onchocerca volvulus 0.0096 0.0047 0.0159
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0003 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Loa Loa (eye worm) D-ets-2 protein 0.0013 0.0002 0.0003
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.01 0.0049 0.0107
Onchocerca volvulus 0.0096 0.0047 0.0159
Toxoplasma gondii exonuclease III APE 0.0014 0.0003 0.0033
Onchocerca volvulus 0.0096 0.0047 0.0159
Onchocerca volvulus 0.0099 0.0049 0.0165
Brugia malayi Tnks protein 0.0586 0.0314 0.0314
Echinococcus granulosus carbonyl reductase 1 0.0096 0.0047 0.0103
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0096 0.0047 0.0159
Trypanosoma cruzi DNA repair protein, putative 0.01 0.0049 0.0107
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0028 0.001 0.0021
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0013 0.0002 0.0004
Onchocerca volvulus 0.0702 0.0378 0.1274
Echinococcus multilocularis sex peptide receptor 0.0702 0.0378 0.0901
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0021 0.0046
Brugia malayi Latrophilin receptor protein 2 0.0237 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0019
Onchocerca volvulus 0.0096 0.0047 0.0159
Echinococcus multilocularis stromal interaction molecule 1 0.004 0.0016 0.0039
Brugia malayi nuclear receptor NHR-88 0.0023 0.0008 0.0007
Mycobacterium ulcerans short-chain dehydrogenase 0.0096 0.0047 0.0133
Echinococcus multilocularis serotonin receptor 0.2585 0.1404 0.3349
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0702 0.0378 0.0901
Mycobacterium ulcerans short-chain dehydrogenase 0.0096 0.0047 0.0133
Leishmania major C-8 sterol isomerase-like protein 0.8378 0.4561 1
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0002 0.0003
Echinococcus granulosus regulator of G protein signaling 3 0.0013 0.0002 0.0004
Echinococcus multilocularis muscleblind protein 1 0.0634 0.0341 0.0812
Schistosoma mansoni hypothetical protein 0.004 0.0016 0.0055
Trichomonas vaginalis set domain proteins, putative 0.1118 0.0604 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0096 0.0047 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0041 0.0017 0.0044
Entamoeba histolytica protein kinase, putative 0.0019 0.0005 0.0061
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0015 0.0003 0.0037
Mycobacterium tuberculosis Possible penicillin-binding protein 0.11 0.0594 0.1747
Mycobacterium tuberculosis Probable reductase 0.011 0.0055 0.0156
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0011 0.0026
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0749 0.0403 0.0883
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0032 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Mycobacterium leprae Possible regulatory protein 0.0016 0.0003 0.0151
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0094 0.0046 0.0046
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0011 0.0182
Giardia lamblia Short-chain dehydrogenase, putative 0.0096 0.0047 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0013 0.0002 0.0006
Brugia malayi larval opioid receptor 0.0702 0.0378 0.0377
Onchocerca volvulus 0.0049 0.0022 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0702 0.0378 0.1274
Leishmania major dehydrogenase-like protein 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.003 0.0011 0.1055
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0037 0.0602
Echinococcus granulosus peptide allatostatin:somatostatin 0.0702 0.0378 0.0825
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0024
Trypanosoma cruzi pyruvate kinase 2, putative 0.0024 0.0008 0.0016
Echinococcus granulosus 7tm_1 domain containing protein 0.0702 0.0378 0.0825
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.004 0.0016 0.0039
Echinococcus multilocularis WNT 0.0081 0.0039 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0041 0.0017 0.0044
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0096 0.0047 0.0103
Brugia malayi conserved hypotetical protein 0.0023 0.0008 0.0007
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0022 0.0047
Echinococcus granulosus bloom syndrome protein 0.0014 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0172 0.0089 0.0255
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0172 0.0089 0.0299
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0022 0.0047
Schistosoma mansoni serine/threonine-protein kinase 0.0013 0.0002 0.0005
Echinococcus granulosus allatostatin A receptor 0.0702 0.0378 0.0825
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.0008 0.0017
Mycobacterium ulcerans dehydrogenase 0.0096 0.0047 0.0133
Echinococcus multilocularis mitogen activated protein kinase 3 0.0027 0.001 0.0022
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0077 0.0037 0.3981
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Brugia malayi cytoplasmic intermediate filament protein 0.0074 0.0035 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0041 0.0017 0.0044
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0014 0.0003 0.0313
Schistosoma mansoni hypothetical protein 0.0103 0.0051 0.0171
Brugia malayi nuclear hormone receptor 0.0049 0.0022 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0702 0.0378 0.1274
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0012 0.0001 0.0002
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0014 0.0003 0.0005
Loa Loa (eye worm) MH1 domain-containing protein 0.0013 0.0002 0.0004
Onchocerca volvulus 0.0107 0.0053 0.018
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0096 0.0047 0.0577
Plasmodium falciparum calcium-dependent protein kinase 4 0.0019 0.0005 0.0999
Trypanosoma cruzi cytochrome P450, putative 0.0075 0.0036 0.0077
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0702 0.0378 0.0377
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0013 0.0002 0.0006
Echinococcus granulosus serine/threonine protein kinase 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0037 0.0602
Mycobacterium tuberculosis Possible oxidoreductase 0.0096 0.0047 0.0133
Echinococcus multilocularis RUN 0.0055 0.0025 0.0059
Brugia malayi hypothetical protein 0.0055 0.0025 0.0025
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0028 0.001 0.0021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0003 0.0005
Echinococcus multilocularis lipoxygenase domain containing protein 0.0055 0.0025 0.0059
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.0008 0.0017
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0022 0.0047
Echinococcus granulosus Regulator of G protein signaling 20 0.0013 0.0002 0.0004
Schistosoma mansoni hypothetical protein 0.0907 0.0489 0.1649
Echinococcus granulosus calcium dependent protein kinase 0.0018 0.0005 0.001
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0051 0.0022 0.2344
Echinococcus multilocularis conserved hypothetical protein 0.77 0.4191 1
Entamoeba histolytica protein kinase, putative 0.0018 0.0005 0.0058
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Toxoplasma gondii endonuclease IV APN 0.0051 0.0022 0.0274
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0143 0.0073 0.0889
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0229 0.012 0.026
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0028 0.001 0.0125
Onchocerca volvulus 0.0702 0.0378 0.1274
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0001 0.0001
Schistosoma mansoni survival motor neuron protein 0.019 0.0099 0.0332
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0006 0.0098
Onchocerca volvulus 0.0702 0.0378 0.1274
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0016 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0096 0.0047 0.0103
Brugia malayi Smad1 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0096 0.0047 0.0133
Schistosoma mansoni adenoreceptor 0.0702 0.0378 0.1274
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.0039
Schistosoma mansoni pyruvate kinase 0.0024 0.0008 0.0026
Echinococcus multilocularis regulator of G protein signaling 0.0013 0.0002 0.0004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0055 0.0025 0.0059
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0009 0.0021
Brugia malayi dehydrogenases, short chain protein 9 0.0096 0.0047 0.0047
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0003 0.0053
Leishmania major DNA repair protein, putative 0.01 0.0049 0.0107
Onchocerca volvulus 0.0137 0.007 0.0234
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0702 0.0378 0.1274
Entamoeba histolytica hypothetical protein, conserved 0.0096 0.0047 0.0586
Echinococcus granulosus dnaJ subfamily C 6 0.0045 0.002 0.0042
Brugia malayi ORL1-like opioid receptor 0.0702 0.0378 0.0377
Schistosoma mansoni biogenic amine (5HT) receptor 0.2585 0.1404 0.4736
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0096 0.0047 0.0778
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0006 0.0013
Brugia malayi A-kinase anchor protein 10, precursor 0.0013 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0014 0.0003 0.0002
Schistosoma mansoni alpha glucosidase 0.0038 0.0016 0.0052
Echinococcus multilocularis neuropeptide Y receptor 0.0702 0.0378 0.0901
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0002 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0172 0.0089 0.1465
Echinococcus granulosus cytochrome P450 2K1 0.0041 0.0017 0.0037
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0255
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0016 0.0191
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0029 0.0011 0.001
Loa Loa (eye worm) Smad1 0.0013 0.0002 0.0004
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0003 0.0008
Mycobacterium leprae conserved hypothetical protein 0.0172 0.0089 1
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Leishmania major short chain dehydrogenase/reductase, putative 0.0096 0.0047 0.0103
Mycobacterium ulcerans putative regulatory protein 0.0045 0.0019 0.005
Echinococcus multilocularis g-protein coupled receptor 0.0702 0.0378 0.0901
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0096 0.0047 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0008 0.0016
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0096 0.0047 0.0159
Plasmodium falciparum protein kinase, putative 0.004 0.0016 0.3407
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.0003 0.0002
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0003 0.0053
Schistosoma mansoni nuclear receptor 0.0023 0.0008 0.0025
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0003 0.0039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0022 0.0022
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0702 0.0378 0.1274
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0027 0.001 0.002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0013 0.0002 0.0004
Leishmania major 3-keto-dihydrosphingosine reductase 0.0096 0.0047 0.0103
Echinococcus granulosus g protein coupled receptor 0.0702 0.0378 0.0825
Trypanosoma cruzi cAMP response protein 1, putative 0.0014 0.0003 0.0005
Mycobacterium ulcerans beta-lactamase 0.0172 0.0089 0.0255
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0047 0.0133
Schistosoma mansoni DNA ligase IV 0.003 0.0011 0.0037
Echinococcus multilocularis neuropeptide Y receptor 0.0702 0.0378 0.0901
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0006 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0041 0.0017 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0702 0.0378 0.1274
Brugia malayi nuclear receptor NHR-67 0.0023 0.0008 0.0007
Schistosoma mansoni hypothetical protein 0.0603 0.0324 0.1091
Entamoeba histolytica hypothetical protein 0.003 0.0011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.0008 0.0007
Toxoplasma gondii aldehyde dehydrogenase 0.0043 0.0018 0.0222
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0003 0.004
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0006 0.0686
Brugia malayi nuclear hormone receptor 0.0023 0.0008 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.012 0.0403
Brugia malayi Melibiase family protein 0.0052 0.0023 0.0023
Echinococcus granulosus ETS transcription factor Elf 2 0.0013 0.0002 0.0003
Brugia malayi wnt family protein 0.0081 0.0039 0.0039
Echinococcus granulosus expressed protein 0.0258 0.0135 0.0295
Echinococcus multilocularis musashi 0.0137 0.007 0.0166
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0022 0.0051
Loa Loa (eye worm) hypothetical protein 0.0338 0.0179 0.0392
Plasmodium falciparum calcium-dependent protein kinase 1 0.0019 0.0005 0.0999
Echinococcus granulosus smad 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0022 0.0022
Schistosoma mansoni histamine h1 receptor 0.0702 0.0378 0.1274
Echinococcus multilocularis mitogen activated protein kinase 0.0027 0.001 0.0022
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0003 0.0003
Schistosoma mansoni poly [ADP-ribose] polymerase 0.1481 0.0802 0.2705
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0052 0.0023 0.0383
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0011 0.0035
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0028 0.001 0.0022
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0011 0.0011
Brugia malayi Doublecortin family protein 0.0055 0.0025 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0078 0.0038 0.0089
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0006 0.1063
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Echinococcus multilocularis fmrfamide receptor 0.0702 0.0378 0.0901
Brugia malayi hypothetical protein 0.0096 0.0047 0.0047
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0022 0.0051
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0012
Trypanosoma cruzi ISWI complex protein 0.0011 0.0001 0.0001
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0096 0.0047 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0008 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0022 0.0073
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0003 0.0291
Echinococcus granulosus Smad4 0.0013 0.0002 0.0004
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0032 0.0012 0.0025
Echinococcus multilocularis nervana 2 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0024
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.002 0.0006 0.0012
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0006 0.1211
Chlamydia trachomatis endonuclease IV 0.0051 0.0022 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0009 0.0019
Brugia malayi Calcitonin receptor-like protein seb-1 0.0749 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Trichomonas vaginalis myo inositol monophosphatase, putative 0.006 0.0028 0.0453
Brugia malayi regulator of G-protein signaling egl-10 0.0018 0.0005 0.0004
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0156 0.008 0.019
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.002 0.0006 0.0014
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0013 0.0002 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3614 0.1964 0.4687
Brugia malayi Cytochrome P450 family protein 0.0041 0.0017 0.0017
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0702 0.0378 0.0901
Mycobacterium ulcerans transcriptional regulatory protein 0.0014 0.0003 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0005 0.001
Schistosoma mansoni neuropeptide receptor 0.0702 0.0378 0.1274
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0012 0.0001 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0002 0.0008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0013 0.0002 0.0004
Echinococcus multilocularis tar DNA binding protein 0.027 0.0142 0.0339
Mycobacterium tuberculosis Possible oxidoreductase 0.0096 0.0047 0.0133
Plasmodium vivax tyrosine kinase-like protein, putative 0.004 0.0016 0.1844
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0172 0.0089 0.1465
Brugia malayi hypothetical protein 0.0013 0.0002 0.0002
Leishmania major trypanothione reductase 0.0048 0.0021 0.0046
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0041 0.0017 0.0044
Trichomonas vaginalis rotamase, putative 0.0023 0.0007 0.0118
Schistosoma mansoni smad1 5 8 and 0.0013 0.0002 0.0006
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Entamoeba histolytica PH domain containing protein kinase, putative 0.0013 0.0002 0.002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0702 0.0378 0.0377
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0011 0.0137
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0014 0.0003 0.0005
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.002 0.0006 0.0012
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.0008 0.0016
Entamoeba histolytica hypothetical protein 0.0208 0.0108 0.1349
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0013 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Plasmodium falciparum glutathione reductase 0.0017 0.0004 0.0756
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.0089 0.0194
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0028 0.001 0.0022
Entamoeba histolytica short chain dehydrogenase family protein 0.0096 0.0047 0.0586
Brugia malayi Bromodomain containing protein 0.0063 0.0029 0.0029
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0015 0.0003 0.001
Echinococcus multilocularis ETS transcription factor Elf 2 0.0013 0.0002 0.0004
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0096 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.0819 0.0441 0.0967
Schistosoma mansoni topbp1 0.003 0.0011 0.0037
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.0062 0.0176
Plasmodium vivax multidomain scavenger receptor, putative 0.0055 0.0025 0.2787
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0003 0.0473
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0041 0.0017 0.0044
Giardia lamblia Pyruvate kinase 0.0024 0.0008 0.1467
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0028 0.001 0.0125
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0096 0.0047 0.0103
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0094 0.0046 0.0101
Echinococcus granulosus g protein coupled receptor 0.0702 0.0378 0.0825
Brugia malayi hypothetical protein 0.0082 0.0039 0.0039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0022 0.0073
Echinococcus multilocularis zinc finger protein 0.0021 0.0006 0.0015
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0011 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0047 0.0103
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0702 0.0378 0.1274
Schistosoma mansoni sarm1 0.004 0.0016 0.0055
Chlamydia trachomatis pyruvate kinase 0.0024 0.0008 0.2711
Echinococcus multilocularis expressed conserved protein 0.0015 0.0003 0.0007
Schistosoma mansoni opsin-like receptor 0.0702 0.0378 0.1274
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.0089 0.0193
Brugia malayi RNA binding protein 0.027 0.0142 0.0142
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0927 0.05 0.1686
Echinococcus granulosus protein Wnt 1 0.0081 0.0039 0.0085
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0096 0.0047 0.0133
Brugia malayi DnaJ domain containing protein 0.0045 0.002 0.0019
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0043 0.0018 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0003 0.0053
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0003 0.0006
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0832 0.0448 0.0983
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0011 0.2304
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.1135 0.0613 0.1345
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0016 0.0192
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0702 0.0378 0.0901
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0004 0.0008
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0015 0.0032
Echinococcus granulosus hypothetical protein 0.0096 0.0047 0.0103
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0011 0.0025
Echinococcus granulosus retinol dehydrogenase 11 0.0096 0.0047 0.0103
Onchocerca volvulus 0.0702 0.0378 0.1274
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0054 0.0024 0.0065
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0019 0.0005 0.0575
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0022 0.0022
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0005 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0172 0.0089 0.1465
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0008 0.0007
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0003 0.004
Brugia malayi Protein kinase domain containing protein 0.0011 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.012 0.0403
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Trichomonas vaginalis steroid dehydrogenase, putative 0.0096 0.0047 0.0778
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0009 0.003
Echinococcus multilocularis ewsr:fli fusion protein type 0.0013 0.0002 0.0004
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0002 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0094 0.0046 0.011
Brugia malayi PHD-finger family protein 0.0025 0.0009 0.0008
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0003 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0022 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Echinococcus granulosus dro:myosuppressin receptor 0.0702 0.0378 0.0825
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0043 0.0018 0.0043
Schistosoma mansoni protein kinase 0.0019 0.0005 0.0017
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0006 0.0012
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0005 0.0077
Loa Loa (eye worm) latrophilin receptor protein 2 0.0237 0.0124 0.0271
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0004 0.0756
Loa Loa (eye worm) hypothetical protein 0.0081 0.0039 0.0085
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0022 0.0073
Loa Loa (eye worm) RGS-3 protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0022 0.0047
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0035
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Loa Loa (eye worm) AGC/PKG protein kinase 0.0015 0.0003 0.0006
Brugia malayi Dopamine receptor 0.0702 0.0378 0.0377
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0016 0.0268
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0096 0.0047 0.0103
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0702 0.0378 0.0901
Brugia malayi hypothetical protein 0.0192 0.0099 0.0099
Schistosoma mansoni lipoxygenase 0.0197 0.0102 0.0344
Trichomonas vaginalis helicase, putative 0.0024 0.0008 0.0131
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0018 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0022 0.0047
Brugia malayi TAR-binding protein 0.027 0.0142 0.0142
Echinococcus multilocularis expressed protein 0.0258 0.0135 0.0322
Loa Loa (eye worm) pyruvate kinase-PB 0.0017 0.0004 0.0008
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0004 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0001 0.0013
Loa Loa (eye worm) melatonin receptor type 1A 0.0702 0.0378 0.0828
Brugia malayi sulfakinin receptor protein 0.0819 0.0441 0.0441
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0702 0.0378 0.0901
Loa Loa (eye worm) neuropeptide F receptor 0.0702 0.0378 0.0828
Plasmodium vivax calcium-dependent protein kinase, putative 0.0019 0.0005 0.0575
Plasmodium falciparum LCCL domain-containing protein 0.0055 0.0025 0.5196
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0022 0.0047
Plasmodium falciparum tyrosine kinase-like protein 0.004 0.0016 0.3407
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0002 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.6234 0.3392 1
Giardia lamblia Replication factor C, subunit 1 0.003 0.0011 0.2174
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0021 0.005
Trypanosoma cruzi pyruvate kinase 2, putative 0.0024 0.0008 0.0016
Echinococcus multilocularis dro:myosuppressin receptor 0.0702 0.0378 0.0901
Echinococcus multilocularis allatostatin A receptor 0.0702 0.0378 0.0901
Echinococcus granulosus protein C ets 2 0.0013 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Leishmania major hypothetical protein, unknown function 0.0014 0.0003 0.0005
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.1481 0.0802 1
Trypanosoma brucei rac serine-threonine kinase, putative 0.0018 0.0005 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0039 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0011 0.0182
Schistosoma mansoni wnt related 0.0081 0.0039 0.0131
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.006 0.0028 0.0059
Entamoeba histolytica zinc finger protein, putative 0.0208 0.0108 0.1349
Echinococcus granulosus 7TM GPCR rhodopsin 0.0702 0.0378 0.0825
Leishmania major cyclic nucleotide-binding protein-like protein 0.0014 0.0003 0.0005
Brugia malayi Uncoordinated protein 44 0.0016 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.019 0.0099 0.0332
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0005
Echinococcus granulosus geminin 0.0907 0.0489 0.1069
Brugia malayi Protein kinase domain containing protein 0.0018 0.0005 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0107 0.0053 0.0117
Echinococcus granulosus mitogen activated protein kinase 3 0.0027 0.001 0.002
Mycobacterium ulcerans hypothetical protein 0.0172 0.0089 0.0255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.0096 0.0047 0.0103
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0051 0.0022 0.4692
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0006 0.0098
Brugia malayi Isocitrate dehydrogenase 0.0013 0.0002 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0088 0.0043 0.0707
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0078 0.0038 0.0082
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0003 0.0006
Onchocerca volvulus 0.019 0.0099 0.0332
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0041 0.0017 0.0044
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0028 0.001 0.0021
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0172 0.0089 0.0299
Loa Loa (eye worm) CYP4Cod1 0.0075 0.0036 0.0078
Brugia malayi Dopamine receptor protein 2 0.0702 0.0378 0.0377
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0131
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0022 0.0051
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0013 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Brugia malayi beta-lactamase family protein 0.0172 0.0089 0.0088
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Onchocerca volvulus Neuropeptide F receptor homolog 0.0702 0.0378 0.1274
Brugia malayi intermediate filament protein 0.0137 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0172 0.0089 0.0194
Loa Loa (eye worm) hypothetical protein 0.0052 0.0023 0.0051
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0255
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0016 0.0255
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0041 0.0017 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0003 0.0009
Toxoplasma gondii pyruvate kinase PyK1 0.0024 0.0008 0.0098
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0016 0.0192
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0024
Echinococcus granulosus stromal interaction molecule 1 0.004 0.0016 0.0035
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Leishmania major protein kinase, putative 0.0015 0.0003 0.0006
Schistosoma mansoni growth hormone secretagogue receptor 0.0702 0.0378 0.1274
Schistosoma mansoni rotamase 0.0024 0.0008 0.0025
Entamoeba histolytica myo-inositol monophosphatase, putative 0.006 0.0028 0.0341
Echinococcus multilocularis 6 phosphofructokinase 0.0077 0.0037 0.0087
Echinococcus granulosus serine threonine protein kinase nrc 0.0012 0.0001 0.0002
Echinococcus granulosus carbonyl reductase 1 0.0096 0.0047 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0003 0.0005
Brugia malayi RE15519p 0.0702 0.0378 0.0377
Toxoplasma gondii oxidoreductase, putative 0.0096 0.0047 0.0577
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0295 0.0156 0.034
Loa Loa (eye worm) beta-lactamase 0.0172 0.0089 0.0194
Echinococcus multilocularis lamin dm0 0.0137 0.007 0.0166
Schistosoma mansoni smad1 5 8 and 0.0013 0.0002 0.0006
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0022 0.0073
Schistosoma mansoni hypothetical protein 0.004 0.0016 0.0055
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0011 0.0138
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0003 0.0002
Echinococcus granulosus GPCR family 2 0.0237 0.0124 0.0271
Echinococcus granulosus neuropeptide receptor 0.0702 0.0378 0.0825
Schistosoma mansoni tar DNA-binding protein 0.027 0.0142 0.0479
Echinococcus multilocularis tissue type plasminogen activator 0.001 0 0.0001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0006 0.1771
Echinococcus multilocularis SAM domain containing protein 0.004 0.0016 0.0039
Echinococcus multilocularis serotonin receptor 0.2585 0.1404 0.3349
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Brugia malayi MAP kinase sur-1 0.0027 0.001 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0131
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0027 0.001 0.002
Echinococcus granulosus regulator of G protein signaling 3 0.0013 0.0002 0.0004
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0016 0.0255
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.0008 0.0016
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0006 0.1771
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0028 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.4219 0.2294 0.5029
Echinococcus granulosus zinc finger protein 0.0021 0.0006 0.0013
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Brugia malayi phosphofructokinase 0.0077 0.0037 0.0036
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0003 0.0008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0023 0.0007 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0702 0.0378 0.0825
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.0003 0.0006
Trichomonas vaginalis inositol monophosphatase, putative 0.006 0.0028 0.0453
Entamoeba histolytica hypothetical protein 0.0208 0.0108 0.1349
Trypanosoma brucei pyruvate kinase 1 0.0024 0.0008 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0702 0.0378 0.1274
Schistosoma mansoni aldehyde dehydrogenase 0.0043 0.0018 0.0061
Onchocerca volvulus 0.0172 0.0089 0.0299
Onchocerca volvulus Huntingtin homolog 0.0192 0.0099 0.0334
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0172 0.0089 0.0256
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0019
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0004 0.0007
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0086 0.0042 0.0092
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0003 0.0053
Trichomonas vaginalis esterase, putative 0.0172 0.0089 0.1465
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0143 0.0073 0.0173
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0008 0.0016
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0096 0.0047 1
Schistosoma mansoni rab6-interacting 0.0055 0.0025 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Mycobacterium ulcerans regulatory protein 0.0014 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0172 0.0089 0.0194
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.004 0.0016 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0366 0.0195 0.0426
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0032 0.0012 0.0026
Schistosoma mansoni alpha-glucosidase 0.0148 0.0076 0.0254
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus multilocularis transfer RNA-Lys 0.0045 0.0019 0.0045
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.0008 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0702 0.0378 0.0828
Onchocerca volvulus 0.0702 0.0378 0.1274
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0011 0.0024
Echinococcus granulosus muscleblind protein 0.0634 0.0341 0.0744
Echinococcus multilocularis netrin receptor unc 5 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0041 0.0017 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.0008 0.0025
Brugia malayi WGR domain containing protein 0.1135 0.0613 0.0613
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0019 0.0005 0.0009
Brugia malayi 6-phosphofructokinase 0.0077 0.0037 0.0036
Entamoeba histolytica hypothetical protein 0.0013 0.0002 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0022 0.0022
Schistosoma mansoni zinc finger protein 0.0012 0.0001 0.0003
Echinococcus granulosus neuropeptide FF receptor 2 0.0702 0.0378 0.0825
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0006 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0702 0.0378 0.0901
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0014 0.0003 0.0006
Trypanosoma brucei cAMP response protein 1, putative 0.0014 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0027 0.001 0.0021
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0005 0.0012
Mycobacterium ulcerans hypothetical protein 0.0014 0.0003 0.0002
Onchocerca volvulus 0.0096 0.0047 0.0159
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0041 0.0017 0.0044
Brugia malayi Intermediate filament tail domain containing protein 0.0137 0.007 0.0069
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0006 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0022 0.0022
Echinococcus multilocularis carbonyl reductase 1 0.0096 0.0047 0.0112
Loa Loa (eye worm) 6-phosphofructokinase 0.0077 0.0037 0.008
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0096 0.0047 0.0586
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0022 0.0047
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0096 0.0047 0.0133
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0011 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.001 0.0032
Schistosoma mansoni opsin-like receptor 0.0702 0.0378 0.1274
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0041 0.0017 0.0044
Entamoeba histolytica protein kinase, putative 0.0018 0.0005 0.0058
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Toxoplasma gondii kringle domain-containing protein 0.001 0 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0022 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0008 0.0018
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0003 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) dehydrogenase 0.0096 0.0047 0.0103
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0014 0.0003 0.0002
Echinococcus granulosus Sterile alpha motif SAM 0.004 0.0016 0.0035
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0096 0.0047 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0041 0.0017 0.0044
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0014 0.0003 0.0462
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0041 0.0017 0.0044
Leishmania major short chain dehydrogenase/reductase, putative 0.0096 0.0047 0.0103
Onchocerca volvulus 0.0014 0.0003 0.0008
Leishmania major hypothetical protein, conserved 0.0096 0.0047 0.0103
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Echinococcus multilocularis g protein coupled receptor 0.0702 0.0378 0.0901
Echinococcus granulosus SAM domain containing protein 0.004 0.0016 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0096 0.0047 0.532
Trypanosoma brucei DNA repair protein, putative 0.01 0.0049 0.0106
Echinococcus multilocularis rac serine:threonine kinase 0.0013 0.0002 0.0004
Echinococcus multilocularis tankyrase 0.0591 0.0317 0.0756
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.0036 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) PXA domain-containing protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0008 0.0017
Onchocerca volvulus 0.0051 0.0023 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0009 0.0009
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Entamoeba histolytica hypothetical protein 0.0103 0.0051 0.0632
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0006 0.0075
Onchocerca volvulus 0.0096 0.0047 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0003 0.0005
Onchocerca volvulus DNA ligase 3 homolog 0.01 0.0049 0.0166
Schistosoma mansoni biogenic amine (5HT) receptor 0.2518 0.1367 0.4613
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.006 0.0028 0.0059
Onchocerca volvulus 0.0702 0.0378 0.1274
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Schistosoma mansoni tar DNA-binding protein 0.027 0.0142 0.0479
Echinococcus granulosus mothers against decapentaplegic 5 0.0013 0.0002 0.0004
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0019 0.0005 0.001
Schistosoma mansoni tankyrase 0.0592 0.0317 0.107
Trypanosoma brucei cAMP binding protein, putative 0.0014 0.0003 0.0004
Mycobacterium tuberculosis Probable esterase LipL 0.0172 0.0089 0.0256
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0096 0.0047 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0029
Echinococcus multilocularis neuropeptide s receptor 0.0942 0.0508 0.1212
Brugia malayi hypothetical protein 0.003 0.0011 0.0011
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0012 0.0001 0.0002
Schistosoma mansoni wnt related 0.0081 0.0039 0.0131
Echinococcus multilocularis neuropeptide receptor 0.0702 0.0378 0.0901
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Brugia malayi hypothetical protein 0.0933 0.0504 0.0503
Mycobacterium leprae Probable oxidoreductase 0.0096 0.0047 0.5209
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0017
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0004 0.0296
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0096 0.0047 0.5209
Brugia malayi Muscleblind-like protein 0.0634 0.0341 0.034
Schistosoma mansoni retinal dehydrogenase 0.0096 0.0047 0.0159
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0004 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0022 0.0022
Echinococcus granulosus RUN 0.0055 0.0025 0.0054
Echinococcus granulosus g protein coupled receptor 0.0702 0.0378 0.0825
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0137 0.007 0.0152
Echinococcus multilocularis vesicular acetylcholine transporter 0.5448 0.2964 0.7071
Chlamydia trachomatis DNA ligase 0.003 0.0011 0.4353
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0041 0.0017 0.0044
Echinococcus multilocularis aryl hydrocarbon receptor 0.0016 0.0003 0.0008
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0041 0.0017 0.0044
Loa Loa (eye worm) hypothetical protein 0.0237 0.0124 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Brugia malayi Ets-domain containing protein 0.0013 0.0002 0.0001
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Schistosoma mansoni cpg binding protein 0.0107 0.0053 0.018
Leishmania major cytochrome p450-like protein 0.0075 0.0036 0.0077
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0051 0.0022 0.2522
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0143 0.0073 0.0245
Echinococcus granulosus TGF beta signal transducer SmadC 0.0013 0.0002 0.0004
Mycobacterium tuberculosis Probable lipase LipD 0.0172 0.0089 0.0256
Echinococcus multilocularis ETS transcription factor Elf 5 0.0013 0.0002 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0003 0.0009
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.0008 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0006 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0043 0.0018 0.0047
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0041 0.0017 0.0044
Trypanosoma brucei C-8 sterol isomerase, putative 0.8378 0.4561 1
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0039 0.0084
Schistosoma mansoni alpha-1 adrenergic receptor 0.0702 0.0378 0.1274
Brugia malayi N-terminal motif family protein 0.0109 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0172 0.0089 0.0194
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0055 0.0156
Schistosoma mansoni poly [ADP-ribose] polymerase 0.1135 0.0613 0.2069
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.004 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Echinococcus granulosus tm gpcr rhodopsin 0.0702 0.0378 0.0825
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0003 0.0007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0043 0.0018 0.0039
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0003 0.004
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0024
Brugia malayi PXA domain containing protein 0.0013 0.0002 0.0002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0003 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0014 0.0003 0.0002
Brugia malayi MH1 domain containing protein 0.0013 0.0002 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0004 0.0007
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.0062 0.6886
Loa Loa (eye worm) wnt-4 protein 0.0081 0.0039 0.0085
Mycobacterium tuberculosis Conserved protein 0.0172 0.0089 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Loa Loa (eye worm) cytochrome P450 family protein 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0019
Echinococcus multilocularis tumor protein p63 0.0176 0.0091 0.0216
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0172 0.0089 0.0194
Schistosoma mansoni amine GPCR 0.08 0.0431 0.1453
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus granulosus patatin phospholipase domain containing protein 0.0014 0.0003 0.0005
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0006 0.0013
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0016 0.0268
Schistosoma mansoni wnt-5 0.0081 0.0039 0.0131
Echinococcus multilocularis liprin alpha 2 0.004 0.0016 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) ets-domain-containing protein 0.0013 0.0002 0.0003
Trypanosoma brucei short-chain dehydrogenase, putative 0.0096 0.0047 0.0101
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0702 0.0378 0.1274
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0982 0.053 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0011 0.0182
Toxoplasma gondii carbonyl reductase 1, putative 0.0096 0.0047 0.0577
Onchocerca volvulus Sepiapterin reductase homolog 0.0096 0.0047 0.0159
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0096 0.0047 0.0133
Echinococcus granulosus hypothetical protein 0.0096 0.0047 0.0103
Brugia malayi ecdysone receptor 0.0023 0.0008 0.0007
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0022 0.0051
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) 6-phosphofructokinase 0.0077 0.0037 0.008
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0096 0.0047 0.0133
Onchocerca volvulus 0.1118 0.0604 0.2039
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0016 0.0034
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.006 0.0028 0.0058
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0026 0.0088
Entamoeba histolytica phosphofructokinase, putative 0.0077 0.0037 0.0453
Echinococcus granulosus sterile alpha and tir motif containing protein 0.004 0.0016 0.0035
Onchocerca volvulus 0.0055 0.0025 0.0083
Schistosoma mansoni Smad4 0.0013 0.0002 0.0006
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0109 0.0054 0.0182
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Schistosoma mansoni carbonyl reductase 0.0096 0.0047 0.0159
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0019 0.0005 0.0063
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0041 0.0017 0.0044
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Echinococcus granulosus steroid dehydrogenase 0.0096 0.0047 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Schistosoma mansoni lamin 0.0137 0.007 0.0234
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0022 0.0022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Brugia malayi putative neuropeptide receptor 0.0702 0.0378 0.0377
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0022 0.0073
Brugia malayi Thioredoxin reductase 0.0048 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0019
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0022 0.0047
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0041 0.0017 0.0044
Toxoplasma gondii pyruvate kinase PyKII 0.0012 0.0002 0.002
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0003 0.0053
Echinococcus granulosus death domain containing protein 0.001 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0003 0.0039
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0006 0.0095
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0003 0.0005
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0013 0.0002 0.0003
Toxoplasma gondii oxidoreductase, putative 0.0096 0.0047 0.0577
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0013 0.0002 0.0031
Echinococcus granulosus tm gpcr rhodopsin 0.3614 0.1964 0.4295
Echinococcus granulosus G protein coupled receptor 139 0.0702 0.0378 0.0825
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0028 0.001 0.1148
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0021 0.0057
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0006 0.0019
Echinococcus granulosus histone lysine methyltransferase setb 0.0156 0.008 0.0174
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Echinococcus granulosus netrin receptor unc 5 0.001 0.0001 0.0001
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0006 0.0012
Brugia malayi PXA domain containing protein 0.0013 0.0002 0.0002
Toxoplasma gondii thioredoxin reductase 0.0048 0.0021 0.026
Brugia malayi Trypsin family protein 0.0058 0.0026 0.0026
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0702 0.0378 0.0825
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0004 0.0007
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Brugia malayi Pre-SET motif family protein 0.0982 0.053 0.053
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0028 0.001 0.002
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0022 0.0073
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0008 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0051 0.0171
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0702 0.0378 0.0901
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0041 0.0017 0.0044
Leishmania major regulatory subunit of protein kinase a-like protein 0.0014 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0027 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.001
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0021 0.239
Echinococcus granulosus tachykinin peptides receptor 99D 0.0702 0.0378 0.0825
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0047 0.0133
Schistosoma mansoni hypothetical protein 0.0237 0.0124 0.0418
Brugia malayi wnt family protein 0.0081 0.0039 0.0039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0103 0.0051 0.0121
Schistosoma mansoni hypothetical protein 0.0702 0.0378 0.1274
Echinococcus multilocularis wnt family member wnt11 2 0.0081 0.0039 0.0093
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0041 0.0017 0.0044
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0702 0.0378 0.0901
Schistosoma mansoni zinc finger protein 0.0021 0.0006 0.0021
Mycobacterium ulcerans ketoacyl reductase 0.0096 0.0047 0.0133
Schistosoma mansoni hypothetical protein 0.0013 0.0002 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0003 0.0041
Leishmania major hypothetical protein, conserved 0.0014 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0172 0.0089 0.0193
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.006 0.0028 0.559
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0255
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0096 0.0047 1
Trypanosoma cruzi Flagellar Member 6 0.0014 0.0003 0.0005
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0003 0.0006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0003 0.0039
Entamoeba histolytica pyruvate kinase, putative 0.0017 0.0004 0.0047
Echinococcus granulosus beta-adrenergic receptor kinase 0.0014 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0064 0.003 0.0064
Brugia malayi p70 ribosomal S6 kinase beta 0.0017 0.0004 0.0004
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0014 0.0002 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0002 0.0006
Loa Loa (eye worm) dehydrogenase 0.0096 0.0047 0.0103
Echinococcus granulosus somatostatin receptor 0.0702 0.0378 0.0825
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0023 0.0007 0.0015
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0014 0.0003 0.0002
Brugia malayi Cytochrome P450 family protein 0.0096 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0004 0.0049
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0012 0.0001 0.0135
Loa Loa (eye worm) tnks protein 0.0552 0.0296 0.0648
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0007
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0096 0.0047 0.0103
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.01 0.0049 0.0106
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0014 0.0002 0.0005
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0053 0.0024 0.0056
Trichomonas vaginalis CMGC family protein kinase 0.0027 0.001 0.0155
Schistosoma mansoni neuropeptide receptor 0.0702 0.0378 0.1274
Echinococcus granulosus fmrfamide receptor 0.0702 0.0378 0.0825
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0096 0.0047 0.0103
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0022 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0003 0.0053
Entamoeba histolytica hypothetical protein 0.0013 0.0002 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.006 0.0028 0.0075
Trypanosoma cruzi ISWI complex protein 0.0012 0.0001 0.0002
Echinococcus multilocularis lamin 0.0137 0.007 0.0166
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0016 0.0255
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0003 0.0002
Echinococcus granulosus ewsr:fli fusion protein type 0.0013 0.0002 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0237 0.0124 0.0271
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0011 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Brugia malayi cytochrome P450 0.0041 0.0017 0.0017
Trypanosoma cruzi short chain dehydrogenase, putative 0.0096 0.0047 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0041 0.0017 0.0044
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Schistosoma mansoni 6-phosphofructokinase 0.0077 0.0037 0.0123
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0006 0.0074
Schistosoma mansoni hypothetical protein 0.0907 0.0489 0.1649
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.0008 0.0017
Echinococcus granulosus liprin beta 1 0.004 0.0016 0.0035
Entamoeba histolytica phosphofructokinase, putative 0.0077 0.0037 0.0453
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0011 0.0182
Mycobacterium leprae putative cytochrome p450 0.0041 0.0017 0.1723
Echinococcus multilocularis GA binding protein alpha chain 0.0086 0.0042 0.01
Onchocerca volvulus 0.0014 0.0003 0.0008
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0577
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0003 0.0006
Schistosoma mansoni 6-phosphofructokinase 0.0077 0.0037 0.0123
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0014 0.0002 0.0005
Schistosoma mansoni biogenic amine receptor 0.0702 0.0378 0.1274
Loa Loa (eye worm) cytochrome P450 0.0041 0.0017 0.0037
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0577
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0041 0.0017 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.0103 0.0051 0.0171
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0026 0.0088
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0002 0.0031
Echinococcus multilocularis neuropeptide FF receptor 2 0.0702 0.0378 0.0901
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.001 0.0001 0.0001
Brugia malayi PAS domain containing protein 0.006 0.0028 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0702 0.0378 0.0901
Echinococcus granulosus neuropeptides capa receptor 0.0702 0.0378 0.0825
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0702 0.0378 0.0825
Echinococcus granulosus pyruvate kinase 0.0024 0.0008 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0002 0.0006
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0096 0.0047 0.0101
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0096 0.0047 0.0586
Loa Loa (eye worm) neuropeptide F receptor 0.0702 0.0378 0.0828
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0014 0.0003 0.0291
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Loa Loa (eye worm) CWN-2 protein 0.0081 0.0039 0.0085
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0041 0.0017 0.0044
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0004 0.0008
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.0008 0.0016
Leishmania major pteridine reductase 1 0.0096 0.0047 0.0103
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0003 0.0005
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0013 0.0002 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0229 0.012 0.0261
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.0003 0.0005
Brugia malayi hypothetical protein 0.0055 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0035
Leishmania major cytochrome p450-like protein 0.0041 0.0017 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0006 0.0098
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0012 0.0026
Schistosoma mansoni steroid dehydrogenase 0.0096 0.0047 0.0159
Onchocerca volvulus 0.004 0.0016 0.0055
Echinococcus granulosus protein Wnt 2 0.0081 0.0039 0.0085
Trypanosoma cruzi ISWI complex protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0952 0.0513 0.1125
Onchocerca volvulus 0.0137 0.007 0.0234
Trichomonas vaginalis pyruvate kinase, putative 0.0024 0.0008 0.0129
Brugia malayi transcription factor E74 isoform 0.0013 0.0002 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0006 0.002
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0006 0.0014
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0019 0.0005 0.0063
Brugia malayi WGR domain containing protein 0.1481 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0051 0.0022 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.6234 0.3392 1
Echinococcus multilocularis pyruvate kinase 0.0012 0.0002 0.0003
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0003 0.0053
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0008 0.0025
Entamoeba histolytica hypothetical protein, conserved 0.0096 0.0047 0.0586
Schistosoma mansoni hypothetical protein 0.0702 0.0378 0.1274
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0096 0.0047 0.0159
Schistosoma mansoni zinc finger protein 0.0023 0.0008 0.0025
Schistosoma mansoni protein kinase 0.0019 0.0005 0.0017
Trypanosoma brucei cytochrome P450, putative 0.0075 0.0036 0.0076
Echinococcus granulosus aryl hydrocarbon receptor 0.0016 0.0003 0.0007
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0096 0.0047 0.5209
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0096 0.0047 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0096 0.0047 0.0133
Brugia malayi hypothetical protein 0.003 0.0011 0.0011
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.5209
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.0036 0.0078
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0172 0.0089 0.0088
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0096 0.0047 0.0103
Schistosoma mansoni hypothetical protein 0.001 0 0.0001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0038 0.0126
Echinococcus granulosus mitogen activated protein kinase 0.0027 0.001 0.002
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0003 0.0032
Echinococcus granulosus vesicular acetylcholine transporter 0.5448 0.2964 0.648
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0008
Echinococcus granulosus expressed protein 0.0024 0.0008 0.0016
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0006 0.0019
Onchocerca volvulus 0.0016 0.0003 0.0011
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0066 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.008 0.0038 0.0084
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Entamoeba histolytica short chain dehydrogenase family protein 0.0096 0.0047 0.0586
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0011 0.0182
Entamoeba histolytica hypothetical protein 0.0103 0.0051 0.0632
Echinococcus granulosus poly (ADP ribose) polymerase 0.0606 0.0325 0.071
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0002 0.0002
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0096 0.0047 0.0103
Echinococcus multilocularis ETS transcription factor Elf 1 0.0013 0.0002 0.0004
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0041 0.0017 0.0044
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.0008 0.0016
Schistosoma mansoni alpha-glucosidase 0.0148 0.0076 0.0254
Brugia malayi G protein-coupled receptor F59B2.13 0.0702 0.0378 0.0377
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.0008 0.0025
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1333 0.0721 0.0721
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0022 0.0073
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Brugia malayi SET domain containing protein 0.0015 0.0003 0.0003
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0022 0.0047
Onchocerca volvulus 0.0096 0.0047 0.0159
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0702 0.0378 0.0377
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0096 0.0047 0.0112
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0002 0.0004
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0022 0.0051
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.0089 0.0088
Onchocerca volvulus 0.0096 0.0047 0.0159
Echinococcus multilocularis 0.0041 0.0017 0.004
Brugia malayi vesicular acetylcholine transporter unc-17 0.5448 0.2964 0.2963
Schistosoma mansoni amine GPCR 0.0702 0.0378 0.1274
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0702 0.0378 0.1274
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Onchocerca volvulus Huntingtin homolog 0.0192 0.0099 0.0334
Brugia malayi hypothetical protein 0.0053 0.0024 0.0023
Echinococcus multilocularis dnaJ subfamily B 0.0603 0.0324 0.0772
Echinococcus granulosus poly (ADP ribose) polymerase 0.0303 0.016 0.0349
Echinococcus multilocularis GPCR, family 2 0.0237 0.0124 0.0295
Brugia malayi hypothetical protein 0.0023 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Loa Loa (eye worm) hypothetical protein 0.0066 0.0031 0.0067
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Echinococcus multilocularis carbonyl reductase 1 0.0096 0.0047 0.0112
Schistosoma mansoni pyruvate kinase 0.0024 0.0008 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.0378 0.0825
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0.001 0.0021
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0004 0.0013
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0002 0.0003
Echinococcus granulosus dnaJ subfamily B 0.0603 0.0324 0.0707
Onchocerca volvulus Pyruvate kinase homolog 0.0024 0.0008 0.0026
Brugia malayi GnHR receptor homolog 0.0702 0.0378 0.0377
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0011 0.0182
Brugia malayi RNA recognition motif domain containing protein 0.027 0.0142 0.0142
Echinococcus multilocularis survival motor neuron protein 1 0.0933 0.0504 0.1201
Loa Loa (eye worm) glutathione reductase 0.0048 0.0021 0.0046
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Schistosoma mansoni smad1 5 8 and 0.0013 0.0002 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.0062 0.0176
Loa Loa (eye worm) phosphofructokinase 0.0077 0.0037 0.008
Toxoplasma gondii hypothetical protein 0.0037 0.0015 0.0183
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0041 0.0017 0.0044
Echinococcus multilocularis beta adrenergic receptor kinase 0.0014 0.0002 0.0005
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0024 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0229 0.012 0.0262
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0038 0.0126
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0022 0.0051
Brugia malayi bHLH-PAS transcription factor 0.0045 0.0019 0.0019
Brugia malayi DNA-binding protein D-ETS-3 0.0013 0.0002 0.0001
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0096 0.0047 0.0133
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0014 0.0003 0.0005
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0003 0.0006
Echinococcus multilocularis retinol dehydrogenase 13 0.0096 0.0047 0.0112
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0096 0.0047 0.0133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0702 0.0378 0.1274
Brugia malayi Liprin-alpha 2 0.004 0.0016 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0041 0.0017 0.0044
Plasmodium falciparum calcium-dependent protein kinase 2 0.0019 0.0005 0.0999
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0016 0.0255
Echinococcus multilocularis Polycystic kidney disease protein 0.0055 0.0025 0.0059
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0008 0.0017
Echinococcus granulosus neuropeptide s receptor 0.0942 0.0508 0.1111
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0014 0.0003 0.0002
Trypanosoma brucei Flagellar Member 6 0.0014 0.0003 0.0004
Giardia lamblia Kinase, CMGC MAPK 0.0027 0.001 0.1817
Echinococcus granulosus 6 phosphofructokinase 0.0077 0.0037 0.0079
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0096 0.0047 0.0586
Echinococcus granulosus carbonyl reductase 1 0.0096 0.0047 0.0103
Brugia malayi G-protein coupled receptor 0.0702 0.0378 0.0377
Echinococcus granulosus neuropeptides capa receptor 0.0702 0.0378 0.0825
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0006 0.0098
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0011 0.0023
Loa Loa (eye worm) AGC/AKT protein kinase 0.0018 0.0005 0.001
Toxoplasma gondii melibiase subfamily protein 0.0078 0.0038 0.0459
Loa Loa (eye worm) oxidoreductase 0.0096 0.0047 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0011 0.0024
Mycobacterium ulcerans dehydrogenase/reductase 0.0096 0.0047 0.0133
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0229 0.012 0.0261
Plasmodium falciparum calcium-dependent protein kinase 3 0.0019 0.0005 0.0999
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0019
Brugia malayi hypothetical protein 0.0702 0.0378 0.0377
Loa Loa (eye worm) MH2 domain-containing protein 0.0189 0.0098 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0006 0.0075
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Schistosoma mansoni ap endonuclease 0.0014 0.0003 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0047
Schistosoma mansoni wnt related 0.0081 0.0039 0.0131
Echinococcus granulosus tar DNA binding protein 0.027 0.0142 0.031
Echinococcus multilocularis cpg binding protein 0.0115 0.0058 0.0137
Mycobacterium ulcerans hypothetical protein 0.0014 0.0003 0.0002
Loa Loa (eye worm) DR-78 0.0023 0.0008 0.0016
Entamoeba histolytica protein kinase, putative 0.0017 0.0004 0.0051
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0096 0.0047 0.0778
Echinococcus granulosus ETS transcription factor Elf 2 0.0013 0.0002 0.0003
Plasmodium falciparum zinc finger protein, putative 0.0014 0.0003 0.0448
Toxoplasma gondii ABC1 family protein 0.0172 0.0089 0.1084
Echinococcus granulosus lipoxygenase domain containing protein 0.0055 0.0025 0.0054
Brugia malayi Regulator of G protein signaling domain containing protein 0.0013 0.0002 0.0002
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0885 0.0477 0.1045
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0013 0.0002 0.0006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0172 0.0089 0.0256
Loa Loa (eye worm) G-protein coupled receptor 0.0702 0.0378 0.0828
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0014 0.0003 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0016 0.0034
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0096 0.0047 0.0778
Brugia malayi coiled-coil like protein 1 0.004 0.0016 0.0016
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0011 0.1262
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0131
Leishmania major hypothetical protein, conserved 0.0096 0.0047 0.0103
Schistosoma mansoni axis inhibition protein axin 0.0013 0.0002 0.0006
Echinococcus granulosus nervana 2 0.0011 0.0001 0.0001
Echinococcus multilocularis oxidoreductase 0.0096 0.0047 0.0112
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0012 0.0001 0.0002
Schistosoma mansoni biogenic amine receptor 0.0702 0.0378 0.1274
Trichomonas vaginalis D-aminoacylase, putative 0.0172 0.0089 0.1465
Echinococcus granulosus alpha 1A adrenergic receptor 0.0702 0.0378 0.0825
Mycobacterium ulcerans transmembrane transport protein 0.0019 0.0005 0.001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0869 0.0468 0.1026
Echinococcus multilocularis protein C ets 2 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0172 0.0089 0.0194
Schistosoma mansoni lar interacting protein (lip)-related protein 0.004 0.0016 0.0055
Echinococcus granulosus pyruvate kinase 0.0024 0.0008 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0022 0.0022
Schistosoma mansoni amine GPCR 0.0702 0.0378 0.1274
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0229 0.012 0.0285
Brugia malayi nuclear receptor RXR 0.0023 0.0008 0.0007
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0004 0.0008
Trypanosoma brucei short-chain dehydrogenase, putative 0.0096 0.0047 0.0101
Brugia malayi MH2 domain containing protein 0.0013 0.0002 0.0002
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0014 0.0003 0.0005
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.001 0.0166
Loa Loa (eye worm) hypothetical protein 0.0082 0.0039 0.0086
Schistosoma mansoni cpg binding protein 0.0115 0.0058 0.0193
Echinococcus multilocularis carbonyl reductase 1 0.0096 0.0047 0.0112
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0003 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.019 0.0099 0.0098
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0096 0.0047 0.0112
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0055 0.0156
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Loa Loa (eye worm) RNA binding protein 0.027 0.0142 0.0311
Mycobacterium tuberculosis Conserved protein 0.0172 0.0089 0.0256
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0004
Trichomonas vaginalis pyruvate kinase, putative 0.0024 0.0008 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0004 0.0008
Leishmania major pyruvate kinase 0.0024 0.0008 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Echinococcus granulosus nuclear factor of activated T cells 5 0.0053 0.0024 0.0051
Schistosoma mansoni myst-related protein 0.0014 0.0003 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0172 0.0089 0.0192
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.5448 0.2964 1
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0511 0.0273 0.0652
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0011 0.0011
Echinococcus granulosus GA binding protein alpha chain 0.0086 0.0042 0.0091
Leishmania major short chain dehydrogenase, putative 0.0096 0.0047 0.0103
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0096 0.0047 0.0586
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0016 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Echinococcus granulosus poly ADP ribose polymerase 1 0.1481 0.0802 0.1753
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0019 0.0005 0.0575
Schistosoma mansoni protein kinase 0.0019 0.0005 0.0017
Leishmania major quinonoid dihydropteridine reductase 0.0096 0.0047 0.0103
Onchocerca volvulus 0.0702 0.0378 0.1274
Loa Loa (eye worm) hypothetical protein 0.2585 0.1404 0.3077
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0019 0.0005 0.0575
Schistosoma mansoni vesicular amine transporter 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Echinococcus granulosus single minded 2 0.0053 0.0024 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0121 0.0061 0.0173
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0039 0.0086
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0096 0.0047 0.0778
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Schistosoma mansoni aldehyde dehydrogenase 0.0043 0.0018 0.0061
Onchocerca volvulus 0.0702 0.0378 0.1274
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0012 0.0041
Trichomonas vaginalis DNA helicase recq1, putative 0.0014 0.0003 0.0038
Echinococcus granulosus lamin dm0 0.0137 0.007 0.0152
Echinococcus granulosus poly adp ribose polymerase 2 0.1135 0.0613 0.1341
Leishmania major cytochrome p450-like protein 0.0041 0.0017 0.0036
Schistosoma mansoni short chain dehydrogenase 0.0096 0.0047 0.0159
Brugia malayi neuropeptide F receptor 0.0702 0.0378 0.0377
Brugia malayi Bloom's syndrome protein homolog 0.0014 0.0003 0.0002
Echinococcus multilocularis carbonyl reductase 1 0.0096 0.0047 0.0112
Onchocerca volvulus 0.0702 0.0378 0.1274
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0004 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0016 0.0268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0022 0.0047
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0096 0.0047 0.0047
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0096 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0096 0.0047 0.0133
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0023 0.0007 0.0014
Echinococcus granulosus oxidoreductase 0.0096 0.0047 0.0103
Echinococcus multilocularis neuropeptides capa receptor 0.0702 0.0378 0.0901
Trypanosoma brucei short-chain dehydrogenase, putative 0.0096 0.0047 0.0101
Schistosoma mansoni wnt related 0.0081 0.0039 0.0131
Leishmania major hypothetical protein, conserved 0.01 0.0049 0.0107
Plasmodium falciparum thioredoxin reductase 0.0017 0.0004 0.0756
Brugia malayi Dopamine receptor protein 1 0.0702 0.0378 0.0377
Echinococcus multilocularis geminin 0.0907 0.0489 0.1166
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0008 0.0016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0038 0.0126
Schistosoma mansoni inositol monophosphatase 0.006 0.0028 0.0092
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Brugia malayi oxidoreductase 0.0096 0.0047 0.0047
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0004 0.0446
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0028 0.001 0.2087
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0013
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0237 0.0124 0.0295
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0013 0.0002 0.0004
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0096 0.0047 0.0103
Echinococcus granulosus Protein Wnt-04 0.0081 0.0039 0.0085
Brugia malayi AKH receptor 0.0702 0.0378 0.0377
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0702 0.0378 0.0825
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0047
Echinococcus granulosus replication factor c subunit 1 0.003 0.0011 0.0024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0041 0.0017 0.0036
Echinococcus granulosus tumor protein p63 0.0176 0.0091 0.0198
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0096 0.0047 0.0577
Brugia malayi neuropeptide F receptor 0.0702 0.0378 0.0377
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0003 0.0008
Schistosoma mansoni hypothetical protein 0.0041 0.0017 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0702 0.0378 0.0901
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0004 0.0756
Echinococcus multilocularis regulator of G protein signaling 3 0.0013 0.0002 0.0004
Onchocerca volvulus 0.0096 0.0047 0.0159
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0025
Schistosoma mansoni hypothetical protein 0.0013 0.0002 0.0005
Brugia malayi CXXC zinc finger family protein 0.0107 0.0053 0.0053
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0077 0.0037 1
Loa Loa (eye worm) hypothetical protein 0.0702 0.0378 0.0828
Onchocerca volvulus 0.0702 0.0378 0.1274
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0229 0.012 0.0285
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0055 0.6111
Mycobacterium ulcerans short chain dehydrogenase 0.0096 0.0047 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0016 0.0268
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0012 0.0026
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0047 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Mycobacterium ulcerans oxidoreductase 0.0096 0.0047 0.0133
Plasmodium vivax pyruvate kinase, putative 0.0024 0.0008 0.0896
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.0378 0.1274
Loa Loa (eye worm) inositol-1 0.006 0.0028 0.006
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0108 0.0054 0.0117
Echinococcus granulosus tankyrase 0.0591 0.0317 0.0693
Loa Loa (eye worm) hypothetical protein 0.0156 0.008 0.0175
Onchocerca volvulus 0.0015 0.0003 0.001
Brugia malayi MH2 domain containing protein 0.0189 0.0098 0.0098
Brugia malayi hypothetical protein 0.004 0.0016 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Echinococcus granulosus cGMP dependent protein kinase 0.0015 0.0003 0.0006
Echinococcus multilocularis Smad4 0.0013 0.0002 0.0004
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0012 0.0002 0.0241
Echinococcus granulosus orexin receptor type 2 0.0702 0.0378 0.0825
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.0108 0.1792
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0237 0.0124 0.0271
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0295 0.0156 0.0371
Echinococcus granulosus nervana 2 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0003
Brugia malayi wnt family protein 0.0081 0.0039 0.0039
Echinococcus multilocularis somatostatin receptor 0.0702 0.0378 0.0901
Trypanosoma cruzi cytochrome P450, putative 0.0075 0.0036 0.0077
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0013 0.0002 0.0226
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.0378 0.0901
Schistosoma mansoni hypothetical protein 0.0014 0.0003 0.0008

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 0.25 uM PubChem BioAssay. Biochemical screen of P. falciparum CDPK1. (Class of assay: confirmatory) ChEMBL. No reference
Inhibition (functional) = -0.85 % ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro ChEMBL. No reference
Inhibition (functional) = -0.27 % ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro ChEMBL. No reference
Inhibition (functional) = -0.01 % ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro ChEMBL. No reference
Inhibition (functional) = 0 % GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM ChEMBL. 20485427
Inhibition (functional) = 50 % GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. ChEMBL. 20485427
Inhibition (functional) = 86 % GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM ChEMBL. 20485427
Inhibition (functional) = 99 % GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM ChEMBL. 20485427
Inhibition frequency index (IFI) (functional) = 5.07 Inhibition Frequency Index (IFI) GSK. 20485427
Percent growth inhibition (functional) = -2 % Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) GSK. 20485427
Percent growth inhibition (functional) = 50 % Percent inhibition of HepG2 growth (at 10 uM) GSK. 20485427
Percent growth inhibition (functional) = 86 % Percent inhibition of P. falciparum Dd2 growth (at 2 uM) GSK. 20485427
Percent growth inhibition (functional) = 99 % Percent inhibition of P. falciparum 3D7 growth (at 2 uM) GSK. 20485427
XC50 (functional) = 6.56 XC50 determination of P. falciparum 3D7 growth GSK. 20485427
XC50 (functional) = 0.27324 uM GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. ChEMBL. 20485427

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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