Detailed information for compound 568039

Basic information

Technical information
  • TDR Targets ID: 568039
  • Name: 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydrox y-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-c hromen-2-one
  • MW: 340.282 | Formula: C15H16O9
  • H donors: 5 H acceptors: 6 LogP: -0.61 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)[C@@H]([C@H]([C@@H]1O)O)O
  • InChi: 1S/C15H16O9/c16-5-10-12(19)13(20)14(21)15(24-10)23-9-3-6-1-2-11(18)22-8(6)4-7(9)17/h1-4,10,12-17,19-21H,5H2/t10-,12-,13+,14-,15-/m1/s1
  • InChiKey: XHCADAYNFIFUHF-TVKJYDDYSA-N  


Substructure search Similarity search

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Synonyms

  • 7-hydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-1-benzopyran-2-one
  • 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-chromen-2-one
  • 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-coumarin
  • 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
  • Esculin
  • 7-hydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-2-chromenone
  • 531-75-9
  • SPBio_000392
  • ZINC03860441
  • IDI1_000956
  • SMP1_000008
  • Spectrum4_001923
  • Spectrum5_000845
  • Spectrum3_000731
  • SR-01000633930-1
  • BCBcMAP01_000202
  • BSPBio_002282
  • Spectrum2_000576
  • 81320_FLUKA
  • Polychrome solution
  • STOCK1N-51823
  • SDCCGMLS-0066653.P001
  • KBio3_001502
  • KBioSS_000841
  • Spectrum_000361
  • C09264
  • Esculoside
  • SPECTRUM1500901
  • KBioGR_002266
  • KBio2_000841
  • KBio2_003409
  • KBio2_005977
  • DivK1c_000956
  • 2H-1-Benzopyran-2-one, 6-(.beta.-D-glucopyranosyloxy)-7-hydroxy-
  • 6-(.beta.-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
  • AIDS-002655
  • AIDS002655
  • Bicolorin
  • Crataegin
  • Enallachrome
  • Escosyl
  • Esculetin 6-O-glucoside
  • Esculetin 6-b-D-glucoside
  • Esculine
  • Polychrom
  • Polychrome
  • Vitamin C2
  • NINDS_000956
  • KBio1_000956

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens caspase 1, apoptosis-related cysteine peptidase Starlite/ChEMBL No references
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens caspase 7, apoptosis-related cysteine peptidase Starlite/ChEMBL No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens androgen receptor Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Homo sapiens arachidonate 15-lipoxygenase, type B Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis caspase Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni caspase-3 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni caspase-7 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus caspase Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K02187 caspase 3, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K04397 caspase 7, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Echinococcus granulosus caspase 8 caspase 1, apoptosis-related cysteine peptidase 383 aa 312 aa 26.6 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Brugia malayi Cell death protein 3 precursor caspase 7, apoptosis-related cysteine peptidase 303 aa 256 aa 37.1 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0011 0.0013
Brugia malayi MH1 domain containing protein 0.009 0.0036 0.0348
Schistosoma mansoni topbp1 0.0132 0.0058 0.0139
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.007 0.0232
Plasmodium vivax exodeoxyribonuclease III, putative 0.0029 0.0002 0.0047
Brugia malayi follicle stimulating hormone receptor 0.0229 0.0111 0.1073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Toxoplasma gondii phosphoglycerate kinase PGKI 0.019 0.009 0.1357
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.008 0.003 0.0295
Loa Loa (eye worm) hypothetical protein 0.0132 0.0058 0.0564
Loa Loa (eye worm) carboxylesterase 0.01 0.0041 0.04
Loa Loa (eye worm) hypothetical protein 0.0298 0.0149 0.1438
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0011 0.0115
Schistosoma mansoni hypothetical protein 0.0798 0.042 0.1021
Loa Loa (eye worm) hypothetical protein 0.0298 0.0149 0.1438
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0145 0.0065 0.1687
Loa Loa (eye worm) hypothetical protein 0.0754 0.0396 0.383
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0114 0.0049 0.0712
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Entamoeba histolytica pyruvate kinase, putative 0.0073 0.0026 0.0244
Mycobacterium ulcerans hypothetical protein 0.017 0.0079 0.2045
Echinococcus granulosus cathepsin L 0.0033 0.0005 0.0006
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0048 0.0013 0.0123
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0037 0.0007 0.017
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0145 0.0065 0.0217
Trichomonas vaginalis D-aminoacylase, putative 0.0298 0.0149 0.1615
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0003 0.012
Schistosoma mansoni retinoic acid receptor RXR 0.0115 0.0049 0.0117
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0049 0.0013 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Onchocerca volvulus 0.0027 0.0002 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0013 0.0136
Giardia lamblia Kinase, PLK 0.0477 0.0246 0.3674
Onchocerca volvulus 0.0121 0.0053 0.0533
Trichomonas vaginalis replication factor C large subunit, putative 0.0132 0.0058 0.0634
Brugia malayi Steroid receptor seven-up type 2 0.0115 0.0049 0.0477
Plasmodium falciparum acyl-CoA synthetase 0.0368 0.0187 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0242 0.0118 0.0285
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.017 0.0079 0.0763
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0048 0.1531
Schistosoma mansoni lozenge 0.0055 0.0017 0.0038
Schistosoma mansoni hypothetical protein 0.0561 0.0291 0.0707
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Mycobacterium tuberculosis Conserved protein 0.0298 0.0149 0.1455
Loa Loa (eye worm) RNA binding protein 0.0521 0.0269 0.2604
Loa Loa (eye worm) hypothetical protein 0.1075 0.057 0.5513
Giardia lamblia Inositol 5-phosphatase 4 0.0029 0.0002 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.002 0.0192
Brugia malayi Cytochrome P450 family protein 0.0055 0.0017 0.0161
Echinococcus granulosus pyruvate kinase 0.0054 0.0016 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Loa Loa (eye worm) matrixin family protein 0.1842 0.0986 0.954
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0145 0.0065 0.098
Brugia malayi nuclear receptor RXR 0.0061 0.002 0.0192
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Schistosoma mansoni zinc finger protein 0.0054 0.0016 0.0037
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0011 0.0025
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0004 0.0037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0011 0.0036
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0141 0.0064 0.3356
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0048 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0115 0.0049 0.0477
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Entamoeba histolytica thioredoxin reductase, putative 0.0027 0.0002 0.0003
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0004 0.0005
Onchocerca volvulus Huntingtin homolog 0.0135 0.006 0.061
Plasmodium vivax vivapain-1 0.023 0.0112 0.5956
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0141 0.0064 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0005 0.0051
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1251 0.0666 0.2124
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0145 0.0065 0.1643
Echinococcus granulosus cpg binding protein 0.0223 0.0108 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0115 0.0049 0.0477
Chlamydia trachomatis phosphoglycerate kinase 0.019 0.009 0.4776
Leishmania major metacaspase, putative 0.0053 0.0016 0.005
Echinococcus granulosus RUN 0.0121 0.0053 0.0061
Trypanosoma cruzi mitochondrial protein 99, putative 0.0029 0.0002 0.0007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0102 0.0042 0.0133
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0016 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0037 0.0007 0.0064
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0323 0.0162 0.2418
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0141 0.0064 0.3365
Schistosoma mansoni tumor necrosis factor receptor related 0.0044 0.0011 0.0023
Schistosoma mansoni pyruvate kinase 0.0105 0.0044 0.0104
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0145 0.0065 0.0076
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0073 0.0026 0.003
Brugia malayi topoisomerase 0.0132 0.0058 0.0564
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.01 0.0041 0.0098
Loa Loa (eye worm) cytochrome P450 family protein 0.0116 0.005 0.048
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0027 0.0002 0.0002
Onchocerca volvulus 0.0029 0.0002 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0058 0.0634
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0828 0.0436 0.0506
Plasmodium vivax acetyl-CoA synthetase, putative 0.0145 0.0065 0.345
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0743 0.039 1
Schistosoma mansoni ap endonuclease 0.0141 0.0064 0.0152
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0115 0.0049 0.0477
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0011 0.0282
Plasmodium falciparum pyruvate kinase 2 0.0054 0.0016 0.0796
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0029 0.0002 0.0026
Echinococcus granulosus pyruvate kinase 0.0105 0.0044 0.0051
Loa Loa (eye worm) beta-lactamase 0.0298 0.0149 0.1438
Echinococcus granulosus lipoxygenase domain containing protein 0.0121 0.0053 0.0061
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0141 0.0064 0.0622
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0005 0.0014
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0124 0.0054 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0678 0.0355 0.3855
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0115 0.0049 0.0117
Echinococcus multilocularis serine protein kinase ATM 0.0694 0.0363 0.0363
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0042 0.001 0.0011
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0145 0.0065 0.0639
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0027 0.0002 0.0002
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0773 0.0406 0.6092
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.026 0.0128 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.072 0.0378 0.4102
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0074 0.0027 0.0261
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0027 0.0002 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0139
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.005 0.0014 0.0136
Echinococcus multilocularis FTZ F1 alpha 0.0115 0.0049 0.0049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0533 0.0276 0.067
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0053 0.0016 0.0036
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0029 0.0002 0.0026
Mycobacterium ulcerans esterase/lipase LipP 0.0298 0.0149 0.3844
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0005 0.0055
Trypanosoma cruzi polo-like protein kinase, putative 0.0477 0.0246 0.0817
Onchocerca volvulus Pyruvate kinase homolog 0.0105 0.0044 0.0439
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0132 0.0058 0.0634
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Echinococcus granulosus caspase 0.0141 0.0064 0.0074
Leishmania major cathepsin L-like protease 0.01 0.0041 0.013
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0002 0.0004
Schistosoma mansoni lipoxygenase 0.0508 0.0262 0.0637
Echinococcus granulosus lamin 0.011 0.0046 0.0054
Giardia lamblia GTOR 0.1251 0.0666 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0115 0.0049 0.0049
Loa Loa (eye worm) cytochrome P450 0.0037 0.0007 0.0065
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0732 0.0384 0.0445
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0048 0.0013 0.0325
Echinococcus multilocularis cpg binding protein 0.0223 0.0108 0.0108
Brugia malayi Phosphoglycerate kinase 0.007 0.0025 0.0239
Echinococcus multilocularis cathepsin L 0.0033 0.0005 0.0005
Onchocerca volvulus 0.017 0.0079 0.0803
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0048 0.0524
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0115 0.0049 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0298 0.0149 0.1615
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0114 0.0049 0.0476
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0115 0.0049 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0115 0.0049 0.0477
Brugia malayi hypothetical protein 0.0117 0.005 0.0487
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0023
Brugia malayi nuclear hormone receptor family member nhr-6 0.0054 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0161 0.0074 0.0716
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.0005 0.0005
Loa Loa (eye worm) inositol-1 0.0045 0.0011 0.0107
Loa Loa (eye worm) pigment dispersing factor receptor c 0.082 0.0432 0.4177
Mycobacterium ulcerans hydrolase 0.0736 0.0386 1
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0029 0.0002 0.0023
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0037 0.0007 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.1232 0.0656 0.7121
Schistosoma mansoni nuclear hormone receptor 0.0115 0.0049 0.0117
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0011 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Loa Loa (eye worm) matrixin family protein 0.1341 0.0714 0.6909
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0074 0.0027 0.0063
Toxoplasma gondii hypothetical protein 0.0052 0.0015 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0004 0.0013
Toxoplasma gondii patched family protein 0.0117 0.005 0.075
Echinococcus multilocularis tar DNA binding protein 0.0521 0.0269 0.0269
Echinococcus granulosus smad 0.009 0.0036 0.0042
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0004 0.0039
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0042 0.001 0.0021
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0242 0.0118 0.0392
Brugia malayi acetyltransferase, GNAT family protein 0.0177 0.0083 0.0804
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0029 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0368 0.0187 0.1804
Echinococcus multilocularis replication factor c subunit 1 0.0132 0.0058 0.0058
Trypanosoma brucei pyruvate kinase 1 0.0105 0.0044 0.0634
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0044 0.0011 0.0034
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0029 0.0002 0.0026
Schistosoma mansoni hypothetical protein 0.0512 0.0265 0.0643
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0073 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0172
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0145 0.0065 0.0639
Loa Loa (eye worm) hypothetical protein 0.0132 0.0058 0.0564
Brugia malayi Calcitonin receptor-like protein seb-1 0.082 0.0432 0.4177
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0368 0.0187 0.1827
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0242 0.0118 0.6296
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0027 0.0002 0.0005
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0003 0.0029
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0027 0.0002 0.0013
Schistosoma mansoni hypothetical protein 0.0062 0.0021 0.0048
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0012 0.0606
Loa Loa (eye worm) phosphatidylinositol 3 0.1251 0.0666 0.6437
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1251 0.0666 0.2217
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0011 0.0109
Entamoeba histolytica hypothetical protein 0.0694 0.0363 0.3504
Echinococcus granulosus Ankyrin 0.0029 0.0002 0.0003
Echinococcus multilocularis mixed lineage leukemia protein mll 0.006 0.0019 0.0019
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0145 0.0065 0.1687
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0048 0.0013 0.0368
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0011 0.012
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0027 0.0002 0.0002
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0754 0.0396 0.6055
Leishmania major cathepsin L-like protease 0.0043 0.001 0.0032
Leishmania major cytochrome p450-like protein 0.0037 0.0007 0.0021
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0029 0.0002 0.0007
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0288 0.0143 0.1402
Schistosoma mansoni polycystin 1-related 0.0121 0.0053 0.0126
Loa Loa (eye worm) hypothetical protein 0.0135 0.006 0.0583
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0257 0.0126 0.042
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0004 0.0007
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0145 0.0065 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0172
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0114 0.0049 0.2554
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1233 0.0656 0.9849
Loa Loa (eye worm) MH2 domain-containing protein 0.004 0.0009 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0694 0.0363 0.3945
Leishmania major hypothetical protein, unknown function 0.0242 0.0118 0.0376
Loa Loa (eye worm) hypothetical protein 0.1015 0.0537 0.5197
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0132 0.0058 0.0872
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1243 0.0661 0.6394
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0074 0.0027 0.0027
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0145 0.0065 0.1687
Onchocerca volvulus Cell death protein 3 homolog 0.0103 0.0043 0.0431
Onchocerca volvulus 0.0298 0.0149 0.1523
Loa Loa (eye worm) hypothetical protein 0.0082 0.0032 0.0306
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0649 0.0339 0.1129
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Trypanosoma cruzi pyruvate kinase 2, putative 0.0105 0.0044 0.0145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0533 0.0276 0.032
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0221 0.0107 0.1615
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0054 0.0016 0.0016
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0037 0.0007 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0029 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.019 0.009 0.087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Trichomonas vaginalis rotamase, putative 0.0033 0.0005 0.005
Trichomonas vaginalis cyclin B, putative 0.005 0.0014 0.0155
Trichomonas vaginalis alpha-glucosidase, putative 0.0117 0.005 0.0548
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0029 0.0002 0.0011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0694 0.0363 0.3512
Brugia malayi AMP-binding enzyme family protein 0.0145 0.0065 0.0632
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0011 0.0115
Brugia malayi RNA binding protein 0.0521 0.0269 0.2604
Trypanosoma cruzi mitochondrial protein 99, putative 0.0029 0.0002 0.0007
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0002 0.0034
Plasmodium vivax unspecified product 0.023 0.0112 0.5956
Plasmodium vivax pyruvate kinase, putative 0.0105 0.0044 0.2275
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0732 0.0384 0.3713
Brugia malayi MH2 domain containing protein 0.009 0.0036 0.0348
Entamoeba histolytica hypothetical protein 0.0242 0.0118 0.1131
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0011 0.0035
Brugia malayi intermediate filament protein 0.011 0.0046 0.0449
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Schistosoma mansoni patched 1 0.0828 0.0436 0.1061
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0027 0.0002 0.0034
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1243 0.0661 0.0767
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.026 0.0128 0.0128
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0493 0.0254 0.6503
Trichomonas vaginalis mercuric reductase, putative 0.0102 0.0042 0.0456
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0782 0.0411 0.0411
Schistosoma mansoni hypothetical protein 0.2413 0.1296 0.3157
Brugia malayi hypothetical protein 0.0782 0.0411 0.3975
Schistosoma mansoni smad 0.004 0.0009 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0141 0.0064 0.0211
Onchocerca volvulus 0.0117 0.005 0.0509
Echinococcus granulosus survival motor neuron protein 1 0.1459 0.0778 0.0903
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0018 0.0248
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0005 0.0047
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1233 0.0656 0.2092
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0649 0.0339 0.3272
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trypanosoma brucei mitotic cyclin 6 0.005 0.0014 0.0191
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0029 0.0002 0.0007
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0295 0.0147 0.141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0533 0.0276 0.067
Trypanosoma brucei DNA polymerase eta, putative 0.0098 0.004 0.058
Leishmania major cysteine peptidase A (CPA) 0.0043 0.001 0.0032
Leishmania major cathepsin L-like protease 0.0043 0.001 0.0032
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0042 0.001 0.001
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0037 0.0007 0.017
Plasmodium falciparum lipid/sterol:H+ symporter 0.0117 0.005 0.2651
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0017 0.0056
Loa Loa (eye worm) phosphatidylinositol 3 0.0242 0.0118 0.1141
Loa Loa (eye worm) hypothetical protein 0.0818 0.0431 0.4165
Brugia malayi phosphofructokinase 0.0113 0.0048 0.0467
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0011 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Schistosoma mansoni nuclear receptor nhr-48 0.0054 0.0016 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0156 0.1696
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Echinococcus multilocularis caspase 0.0141 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0027 0.0002 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0079 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.001 0.0087
Mycobacterium leprae PROBABLE HYDROLASE 0.0736 0.0386 0.9906
Echinococcus granulosus zinc finger protein 0.0035 0.0006 0.0007
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0005 0.0049
Onchocerca volvulus 0.005 0.0014 0.0135
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0027 0.0002 0.0034
Brugia malayi Glycosyl hydrolases family 31 protein 0.0528 0.0273 0.2643
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0583 0.0303 0.2924
Trypanosoma brucei DNA polymerase IV, putative 0.0094 0.0038 0.0546
Echinococcus granulosus replication factor c subunit 1 0.0132 0.0058 0.0068
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0002 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0037 0.0007 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0132 0.0058 0.0194
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0156 0.1696
Echinococcus multilocularis Smad4 0.009 0.0036 0.0036
Loa Loa (eye worm) nuclear hormone receptor 0.0054 0.0016 0.0158
Schistosoma mansoni loxhd1 0.0121 0.0053 0.0126
Entamoeba histolytica acyl-coA synthetase, putative 0.0493 0.0254 0.2449
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0023
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0027 0.0002 0.0014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0033 0.0005 0.0009
Onchocerca volvulus 0.0242 0.0118 0.1207
Schistosoma mansoni smad1 5 8 and 0.009 0.0036 0.0085
Echinococcus granulosus lysine specific demethylase 5A 0.0132 0.0058 0.0068
Loa Loa (eye worm) hypothetical protein 0.0452 0.0232 0.2244
Loa Loa (eye worm) MH2 domain-containing protein 0.1327 0.0707 0.6838
Schistosoma mansoni hypothetical protein 0.0798 0.042 0.1021
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0037 0.0007 0.0064
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0005 0.0035
Echinococcus multilocularis caspase 3 0.0088 0.0035 0.0035
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0048 0.0455
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0027 0.0002 0.0013
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Schistosoma mansoni steroid hormone receptor ad4bp 0.0115 0.0049 0.0117
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Leishmania major trypanothione reductase 0.0293 0.0146 0.0465
Treponema pallidum phosphoglycerate kinase 0.019 0.009 0.2894
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1202 0.0639 0.2039
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0298 0.0149 0.1438
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0156 0.1696
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0145 0.0065 0.0621
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.002 0.0046
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0361 0.0183 0.1759
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0202 0.1945
Echinococcus multilocularis BC026374 protein (S09 family) 0.0045 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.026 0.0128 0.1391
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.2579 0.1386 0.1386
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0014 0.0189
Schistosoma mansoni tar DNA-binding protein 0.0521 0.0269 0.0654
Onchocerca volvulus 0.0043 0.001 0.0094
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0013
Loa Loa (eye worm) CYP4Cod1 0.0055 0.0017 0.0161
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0012 0.0026
Giardia lamblia Phosphoglycerate kinase 0.019 0.009 0.1331
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0027 0.0002 0.0002
Brugia malayi Cyclin, N-terminal domain containing protein 0.005 0.0014 0.0138
Trichomonas vaginalis cyclin B, putative 0.005 0.0014 0.0155
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0145 0.0065 0.0639
Echinococcus multilocularis mothers against decapentaplegic 6 0.004 0.0009 0.0009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0141 0.0064 0.1642
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0037 0.0007 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0493 0.0254 0.6576
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0005 0.0049
Onchocerca volvulus Pyruvate kinase homolog 0.0105 0.0044 0.0439
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0046 0.0449
Onchocerca volvulus 0.0298 0.0149 0.1523
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0012 0.0038
Loa Loa (eye worm) glutaminase 2 0.0278 0.0138 0.1331
Loa Loa (eye worm) hypothetical protein 0.0463 0.0238 0.2304
Brugia malayi beta-lactamase 0.0298 0.0149 0.1438
Treponema pallidum hypothetical protein 0.0029 0.0002 0.0028
Entamoeba histolytica serine/threonine protein kinase, putative 0.0477 0.0246 0.2365
Schistosoma mansoni synaptojanin 0.0029 0.0002 0.0003
Onchocerca volvulus 0.011 0.0046 0.0468
Brugia malayi mothers against decapentaplegic homolog 3 0.004 0.0009 0.0085
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0732 0.0384 0.0933
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0003 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0521 0.0269 0.0654
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1251 0.0666 1
Onchocerca volvulus 0.0154 0.007 0.0715
Echinococcus multilocularis mothers against decapentaplegic 2 0.004 0.0009 0.0009
Entamoeba histolytica cyclin, putative 0.005 0.0014 0.0126
Brugia malayi Cytochrome P450 family protein 0.0037 0.0007 0.0065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0013 0.0136
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0037 0.0007 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Loa Loa (eye worm) histone methyltransferase 0.0073 0.0026 0.0254
Trichomonas vaginalis D-aminoacylase, putative 0.0298 0.0149 0.1615
Schistosoma mansoni glutaminase 0.0278 0.0138 0.0333
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0016 0.0037
Entamoeba histolytica disulphide oxidoreductase, putative 0.0027 0.0002 0.0003
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0033 0.0005 0.0016
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0102 0.0042 0.0139
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0022 0.0212
Toxoplasma gondii patched family protein 0.0117 0.005 0.075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0437 0.0224 0.2431
Entamoeba histolytica cysteine protease, putative 0.0043 0.001 0.0087
Loa Loa (eye worm) glutathione reductase 0.0293 0.0146 0.1411
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0145 0.0065 0.0639
Plasmodium falciparum phosphoglycerate kinase 0.019 0.009 0.4784
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0481 0.0248 0.371
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0242 0.0118 0.1282
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0061 0.002 0.002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0011 0.012
Leishmania major acetyl-CoA synthetase, putative 0.0145 0.0065 0.0208
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0048 0.0524
Leishmania major phosphatidylinositol 3-kinase, putative 0.0295 0.0147 0.0468
Echinococcus multilocularis protein patched 0.0828 0.0436 0.0436
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0029 0.0002 0.0003
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0009 0.0181
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0298 0.0149 0.1615
Mycobacterium leprae Probable lipase LipE 0.0298 0.0149 0.3787
Schistosoma mansoni alpha glucosidase 0.0117 0.005 0.012
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0177 0.0083 0.02
Loa Loa (eye worm) pyruvate kinase-PB 0.0073 0.0026 0.0256
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0025 0.0082
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0298 0.0149 0.3844
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.007 0.0025 0.0082
Brugia malayi nuclear hormone receptor 0.0115 0.0049 0.0477
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0045 0.0011 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0041 0.0137
Echinococcus granulosus TGF beta signal transducer SmadC 0.009 0.0036 0.0042
Schistosoma mansoni coup transcription factor 0.0115 0.0049 0.0117
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0115 0.0049 0.0497
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0042 0.001 0.0124
Toxoplasma gondii pyruvate kinase PyK1 0.0105 0.0044 0.0646
Echinococcus granulosus death domain containing protein 0.0029 0.0002 0.0003
Loa Loa (eye worm) isocitrate dehydrogenase 0.0114 0.0049 0.0472
Toxoplasma gondii FATC domain-containing protein 0.0694 0.0363 0.5551
Trypanosoma brucei RNA editing exonuclease 2 0.0029 0.0002 0.0013
Toxoplasma gondii cytochrome p450 superfamily protein 0.0037 0.0007 0.0081
Onchocerca volvulus 0.0043 0.001 0.0094
Giardia lamblia hypothetical protein 0.0029 0.0002 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0115 0.0049 0.0117
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0003 0.003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0054 0.0129
Onchocerca volvulus 0.0437 0.0224 0.2302
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Echinococcus granulosus para nitrobenzyl esterase 0.0045 0.0011 0.0013
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0004 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Trypanosoma cruzi PAB1-binding protein , putative 0.0161 0.0074 0.0246
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.006 0.0019 0.0019
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0008 0.0091
Brugia malayi N-terminal motif family protein 0.0183 0.0086 0.0831
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0242 0.0118 0.1788
Loa Loa (eye worm) hypothetical protein 0.0298 0.0149 0.1438
Brugia malayi Protein kinase domain containing protein 0.003 0.0003 0.0031
Echinococcus granulosus cytochrome P450 2K1 0.0037 0.0007 0.0008
Echinococcus multilocularis Ankyrin 0.0029 0.0002 0.0002
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0743 0.039 0.3821
Brugia malayi jmjC domain containing protein 0.0118 0.0051 0.0493
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0054 0.0129
Schistosoma mansoni tar DNA-binding protein 0.0521 0.0269 0.0654
Brugia malayi Pyruvate kinase, M2 isozyme 0.0105 0.0044 0.0422
Echinococcus multilocularis expressed protein 0.0033 0.0005 0.0005
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.001 0.001
Loa Loa (eye worm) acetylcholinesterase 1 0.01 0.0041 0.04
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0242 0.0118 0.1788
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.043 0.022 0.0255
Mycobacterium tuberculosis Conserved hypothetical protein 0.017 0.0079 0.0774
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0102 0.0042 0.1082
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0295 0.0147 0.7858
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0348 0.0176 0.172
Echinococcus multilocularis Niemann Pick C1 protein 0.2758 0.1483 0.1483
Schistosoma mansoni pyruvate kinase 0.0054 0.0016 0.0036
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0048 0.0013 0.0608
Loa Loa (eye worm) hypothetical protein 0.0032 0.0004 0.0039
Onchocerca volvulus 0.0145 0.0065 0.0663
Toxoplasma gondii pyruvate kinase PyKII 0.0054 0.0016 0.0222
Schistosoma mansoni nocturnin 0.0029 0.0002 0.0003
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Schistosoma mansoni cyclin B 0.005 0.0014 0.0032
Echinococcus multilocularis RUN 0.0121 0.0053 0.0053
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0027 0.0002 0.0015
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0012 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0115 0.0049 0.0049
Mycobacterium ulcerans aldehyde dehydrogenase 0.043 0.022 0.5691
Trypanosoma brucei unspecified product 0.0051 0.0014 0.0193
Loa Loa (eye worm) glutaminase 0.0278 0.0138 0.1331
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0102 0.0042 0.4578
Entamoeba histolytica hypothetical protein 0.0132 0.0058 0.0553
Mycobacterium tuberculosis Carboxylesterase LipT 0.0308 0.0154 0.1505
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0295 0.0147 0.0489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0298 0.0149 0.1438
Trichomonas vaginalis PIKK family atypical protein kinase 0.1191 0.0633 0.6875
Echinococcus granulosus expressed conserved protein 0.1813 0.0971 0.1125
Brugia malayi nuclear receptor NHR-67 0.0054 0.0016 0.0158
Onchocerca volvulus 0.0045 0.0011 0.0105
Brugia malayi nuclear receptor NHR-88 0.0115 0.0049 0.0477
Trypanosoma cruzi metacaspase, putative 0.0053 0.0016 0.0052
Onchocerca volvulus Mothers against decapentaplegic homolog 0.004 0.0009 0.0079
Plasmodium falciparum cysteine proteinase falcipain 1 0.023 0.0112 0.5962
Brugia malayi serine/threonine-protein kinase plk-2 0.0477 0.0246 0.2374
Schistosoma mansoni acetyl-CoA synthetase 0.0145 0.0065 0.0157
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0027 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0074 0.0027 0.0694
Brugia malayi MH2 domain containing protein 0.1327 0.0707 0.6838
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0048 0.0048
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0002 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0058 0.0634
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.006 0.0019 0.0022
Toxoplasma gondii patched family protein 0.0117 0.005 0.075
Echinococcus granulosus cathepsin l1 0.0043 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0124 0.0054 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0237 0.0116 0.0279
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0141 0.0064 0.0064
Trichomonas vaginalis helicase, putative 0.0047 0.0013 0.0136
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0114 0.0049 0.2564
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Loa Loa (eye worm) thioredoxin reductase 0.0293 0.0146 0.1411
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0736 0.0386 0.3785
Brugia malayi CXXC zinc finger family protein 0.0209 0.01 0.0969
Echinococcus multilocularis synaptojanin 1 0.0029 0.0002 0.0002
Echinococcus granulosus Polycystic kidney disease protein 0.0121 0.0053 0.0061
Schistosoma mansoni survival motor neuron protein 0.0298 0.0148 0.0359
Loa Loa (eye worm) hypothetical protein 0.0098 0.004 0.0387
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0115 0.0049 0.0117
Loa Loa (eye worm) hypothetical protein 0.064 0.0334 0.323
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1202 0.0639 0.9598
Onchocerca volvulus 0.0045 0.0011 0.0105
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0037 0.0007 0.017
Schistosoma mansoni hypothetical protein 0.026 0.0128 0.0309
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0295 0.0147 0.2232
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0002 0.0016
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0029 0.0002 0.0026
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0027 0.0002 0.0015
Onchocerca volvulus 0.0045 0.0011 0.0105
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0006 0.0006
Schistosoma mansoni cript-related 0.0029 0.0002 0.0003
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0002 0.0002
Plasmodium vivax replication factor C subunit 1, putative 0.0132 0.0058 0.307
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0013
Mycobacterium ulcerans phosphoglycerate kinase 0.019 0.009 0.2323
Toxoplasma gondii ABC1 family protein 0.0298 0.0149 0.2258
Brugia malayi exodeoxyribonuclease III family protein 0.0141 0.0064 0.0615
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0108 0.0045 0.0439
Mycobacterium leprae conserved hypothetical protein 0.0298 0.0149 0.3787
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.019 0.009 0.0879
Mycobacterium ulcerans aldehyde dehydrogenase 0.043 0.022 0.5691
Schistosoma mansoni disulfide oxidoreductase 0.0027 0.0002 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0668 0.035 0.3425
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.082 0.0432 0.4177
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0023
Plasmodium falciparum thioredoxin reductase 0.0102 0.0042 0.2198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0037 0.0007 0.0064
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0073 0.0027 0.0031
Leishmania major phosphatidylinositol 3-kinase, putative 0.1191 0.0633 0.2019
Brugia malayi hypothetical protein 0.0061 0.002 0.0192
Schistosoma mansoni cellular tumor antigen P53 0.064 0.0334 0.0811
Onchocerca volvulus Matrix metalloproteinase homolog 0.1341 0.0714 0.7365
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0005 0.0016
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0042 0.001 0.0021
Echinococcus granulosus pyruvate kinase 0.0105 0.0044 0.0051
Onchocerca volvulus 0.0305 0.0153 0.1563
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0145 0.0065 0.0632
Echinococcus multilocularis dna polymerase kappa 0.0101 0.0041 0.0041
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.001 0.0094
Echinococcus multilocularis neuroligin 0.0045 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0115 0.0049 0.0477
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0118 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.1232 0.0656 0.7121
Echinococcus multilocularis lysosomal alpha glucosidase 0.0528 0.0273 0.0273
Mycobacterium leprae Probable pyruvate kinase PykA 0.0105 0.0044 0.1084
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0019 0.0182
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0033 0.0005 0.0051
Brugia malayi STAT protein, DNA binding domain containing protein 0.0159 0.0073 0.0707
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.017 0.0079 0.019
Schistosoma mansoni hypothetical protein 0.0037 0.0007 0.0014
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0037 0.0007 0.017
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0298 0.0149 0.1455
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Loa Loa (eye worm) hypothetical protein 0.0152 0.0069 0.067
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0003 0.0038
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Onchocerca volvulus 0.0115 0.0049 0.0497
Echinococcus multilocularis lamin 0.011 0.0046 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0726 0.0381 0.0442
Leishmania major phosphatidylinositol kinase, putative 0.0242 0.0118 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Brugia malayi Muscleblind-like protein 0.0152 0.0069 0.067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0115 0.0049 0.0057
Giardia lamblia Pyruvate kinase 0.0105 0.0044 0.0634
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0368 0.0187 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0054 0.0063
Onchocerca volvulus 0.0043 0.001 0.0094
Onchocerca volvulus Serine\/threonine kinase homolog 0.0477 0.0246 0.2524
Echinococcus multilocularis lamin dm0 0.011 0.0046 0.0046
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.005 0.0014 0.0045
Loa Loa (eye worm) hypothetical protein 0.0493 0.0254 0.2458
Echinococcus multilocularis lipoxygenase domain containing protein 0.0121 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0368 0.0187 0.1804
Schistosoma mansoni hypothetical protein 0.0072 0.0026 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0298 0.0149 0.0494
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0037 0.0007 0.017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0132 0.0058 0.0564
Leishmania major pantothenate kinase subunit, putative 0.0049 0.0013 0.0042
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0042 0.001 0.0106
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0295 0.0147 0.1421
Onchocerca volvulus 0.064 0.0334 0.3437
Echinococcus granulosus dna polymerase eta 0.0098 0.004 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0037 0.0007 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0115 0.0049 0.0477
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.001 0.0099
Brugia malayi jmjC domain containing protein 0.0132 0.0058 0.0565
Onchocerca volvulus 0.0054 0.0016 0.0157
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Giardia lamblia Replication factor C, subunit 1 0.0132 0.0058 0.0856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0242 0.0118 0.1282
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0054 0.0129
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0016 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0493 0.0254 0.2458
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0295 0.0147 0.2189
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.003 0.0434
Loa Loa (eye worm) phosphatidylinositol 3 0.1202 0.0639 0.6179
Echinococcus multilocularis Polycystic kidney disease protein 0.0121 0.0053 0.0053
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0013 0.0041
Echinococcus granulosus nibrin 0.0132 0.0058 0.0068
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0512 0.0265 0.2561
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.001 0.001
Loa Loa (eye worm) phosphatidylinositol 3 0.0762 0.04 0.3872
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0298 0.0149 0.1455
Trichomonas vaginalis conserved hypothetical protein 0.0437 0.0224 0.2431
Echinococcus granulosus beta LACTamase domain containing family member 0.0298 0.0149 0.0172
Loa Loa (eye worm) hypothetical protein 0.01 0.0041 0.04
Echinococcus multilocularis Zinc finger, PHD finger 0.0295 0.0147 0.0147
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0029 0.0002 0.0023
Trypanosoma brucei trypanothione reductase 0.0293 0.0146 0.2174
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0029 0.0002 0.0026
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0037 0.0007 0.017
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0042 0.001 0.001
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.155 0.0828 0.2015
Trypanosoma brucei glycosyl hydrolase-like protein 0.0044 0.0011 0.0136
Trypanosoma cruzi metacaspase, putative 0.0053 0.0016 0.0052
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0037 0.0007 0.017
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Brugia malayi CCR4 0.0029 0.0002 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0005 0.0035
Schistosoma mansoni Smad4 0.009 0.0036 0.0085
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0004 0.0007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0002 0.0002
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0043 0.001 0.0099
Loa Loa (eye worm) hypothetical protein 0.004 0.0009 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0058 0.0634
Mycobacterium ulcerans hypothetical protein 0.0298 0.0149 0.3844
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0002 0.0004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0073 0.0027 0.0259
Echinococcus multilocularis ecdysone induced protein 78C 0.0115 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0172
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0045 0.0011 0.0013
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0029 0.0002 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0739 0.0388 0.4211
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Trichomonas vaginalis ap endonuclease, putative 0.0141 0.0064 0.0691
Trypanosoma brucei Aminopeptidase M1, putative 0.0042 0.001 0.0124
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0003 0.0038
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0678 0.0355 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Mycobacterium leprae putative cytochrome p450 0.0037 0.0007 0.0135
Onchocerca volvulus Putative neutral sphingomyelinase 0.0029 0.0002 0.0013
Onchocerca volvulus 0.0043 0.001 0.0094
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0145 0.0065 0.0961
Schistosoma mansoni lamin 0.011 0.0046 0.011
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0027 0.0002 0.0013
Schistosoma mansoni pyruvate kinase 0.0105 0.0044 0.0104
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0004 0.0004
Loa Loa (eye worm) phosphatidylinositol 3 0.0242 0.0118 0.1141
Mycobacterium tuberculosis Probable reductase 0.0668 0.035 0.3425
Loa Loa (eye worm) nuclear receptor NHR-67 0.0054 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0678 0.0355 0.3432
Echinococcus multilocularis geminin 0.2413 0.1296 0.1296
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0004 0.0005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0115 0.0049 0.0057
Entamoeba histolytica hypothetical protein 0.0782 0.0411 0.3967
Brugia malayi Melibiase family protein 0.0082 0.0032 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0172
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0145 0.0065 0.0632
Loa Loa (eye worm) Smad1 0.009 0.0036 0.0348
Onchocerca volvulus 0.005 0.0014 0.0132
Toxoplasma gondii phosphoglycerate kinase PGKII 0.019 0.009 0.1357
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0295 0.0147 0.2232
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0104 0.1128
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1251 0.0666 0.6437
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0011
Brugia malayi Matrixin family protein 0.0605 0.0315 0.3045
Leishmania major hypothetical protein, conserved 0.0029 0.0002 0.0007
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0037 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.193 0.1034 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0086 0.0831
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0013
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0029 0.0002 0.0026
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0521 0.0269 0.2604
Trypanosoma cruzi DNA polymerase eta, putative 0.0098 0.004 0.0133
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0649 0.0339 0.1129
Onchocerca volvulus Matrilysin homolog 0.1811 0.0969 1
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0736 0.0386 0.3737
Brugia malayi jmjC domain containing protein 0.0032 0.0004 0.0039
Onchocerca volvulus 0.0209 0.01 0.1022
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0156 0.1696
Entamoeba histolytica hypothetical protein 0.0782 0.0411 0.3967
Schistosoma mansoni hypothetical protein 0.026 0.0128 0.0309
Loa Loa (eye worm) runx1 0.0055 0.0017 0.0161
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0114 0.0049 0.0162
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0002 0.0013
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0075 0.0027 0.0265
Echinococcus multilocularis lysosomal alpha glucosidase 0.0528 0.0273 0.0273
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0668 0.035 0.3425
Schistosoma mansoni tar DNA-binding protein 0.0521 0.0269 0.0654
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0013 0.0608
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0145 0.0065 0.0632
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0054 0.0016 0.0037
Brugia malayi ecdysteroid receptor 0.0115 0.0049 0.0477
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Brugia malayi AMP-binding enzyme family protein 0.0493 0.0254 0.2458
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.019 0.009 0.2275
Schistosoma mansoni cpg binding protein 0.0223 0.0108 0.026
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0295 0.0147 0.0489
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0029 0.0002 0.0061
Trypanosoma cruzi pyruvate kinase 2, putative 0.0105 0.0044 0.0145
Loa Loa (eye worm) carboxylesterase 0.0045 0.0011 0.011
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Trichomonas vaginalis set domain proteins, putative 0.1721 0.0921 1
Echinococcus multilocularis Protein lozenge 0.0055 0.0017 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0011 0.0115
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Trichomonas vaginalis apoptosis inducing factor, putative 0.0027 0.0002 0.0016
Onchocerca volvulus Matrilysin homolog 0.0605 0.0315 0.324
Loa Loa (eye worm) hypothetical protein 0.01 0.0041 0.04
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0145 0.0065 0.1687
Schistosoma mansoni aldehyde dehydrogenase 0.043 0.022 0.0534
Loa Loa (eye worm) intermediate filament protein 0.011 0.0046 0.0449
Trypanosoma cruzi CYC2-like cyclin, putative 0.005 0.0014 0.0047
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0043 0.001 0.0483
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0048 0.0013 0.1273
Mycobacterium ulcerans acetyl-CoA synthetase 0.0145 0.0065 0.1687
Schistosoma mansoni inositol monophosphatase 0.0045 0.0011 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0114 0.0049 0.0049
Loa Loa (eye worm) CXXC zinc finger family protein 0.0209 0.01 0.0969
Loa Loa (eye worm) hypothetical protein 0.0121 0.0053 0.051
Loa Loa (eye worm) hypothetical protein 0.0132 0.0058 0.0564
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0115 0.0049 0.0477
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0027 0.0002 0.0034
Echinococcus multilocularis para nitrobenzyl esterase 0.0045 0.0011 0.0011
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0133
Brugia malayi Cathepsin L-like precursor 0.0043 0.001 0.0099
Echinococcus multilocularis 0.0037 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0037 0.0007 0.017
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.005 0.0014 0.0136
Onchocerca volvulus 0.0298 0.0148 0.152
Brugia malayi PHD-finger family protein 0.004 0.0009 0.0084
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0019 0.0044
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.059 0.0307 0.296
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0005 0.0047
Echinococcus multilocularis acetylcholinesterase 0.01 0.0041 0.0041
Echinococcus multilocularis carboxylesterase 5A 0.01 0.0041 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0004 0.0038
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0037 0.0007 0.017
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0027 0.0002 0.0016
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0029 0.0002 0.0061
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0145 0.0065 0.0632
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0452 0.0232 0.0772
Trypanosoma cruzi metacaspase 5, putative 0.0053 0.0016 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0348 0.0176 0.172
Trypanosoma cruzi phosphoglycerate kinase, putative 0.019 0.009 0.0299
Loa Loa (eye worm) hypothetical protein 0.0368 0.0187 0.1804
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0145 0.0065 0.098
Trypanosoma brucei phosphoglycerate kinase 0.007 0.0025 0.0349
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0011 0.0115
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0016 0.0018
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0732 0.0384 0.0384
Trichomonas vaginalis antibiotic synthetase, putative 0.0145 0.0065 0.071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0115 0.0049 0.0477
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0013 0.0136
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0743 0.039 0.3821
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0054 0.0054
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.001 0.0087
Echinococcus granulosus cathepsin L cysteine protease 0.0033 0.0005 0.0006
Leishmania major cathepsin L-like protease 0.01 0.0041 0.013
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0002 0.0004
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0037 0.0007 0.017
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0145 0.0065 0.0632
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.007 0.0222
Loa Loa (eye worm) hypothetical protein 0.011 0.0046 0.0449
Leishmania major cathepsin L-like protease 0.01 0.0041 0.013
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0048 0.0467
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0002 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0013 0.029
Brugia malayi AMP-binding enzyme family protein 0.0145 0.0065 0.0632
Brugia malayi nuclear hormone receptor 0.0054 0.0016 0.0158
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.001 0.0022
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0132 0.0058 0.0553
Toxoplasma gondii aldehyde dehydrogenase 0.043 0.022 0.3353
Trichomonas vaginalis PIKK family atypical protein kinase 0.1191 0.0633 0.6875
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Echinococcus granulosus neutral sphingomyelinase 0.0029 0.0002 0.0003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0115 0.0049 0.0477
Brugia malayi CHE-14 protein 0.0828 0.0436 0.4219
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0242 0.0118 0.0392
Loa Loa (eye worm) patched family protein 0.0117 0.005 0.0487
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0145 0.0065 0.0065
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0133
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0029 0.0002 0.0013
Schistosoma mansoni glutamate synthase 0.0027 0.0002 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0242 0.0118 0.1141
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0533 0.0276 0.2667
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0019 0.0182
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0044 0.0011 0.0097
Schistosoma mansoni hypothetical protein 0.0298 0.0148 0.0359
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Echinococcus granulosus phd:f box containing protein 0.0032 0.0004 0.0005
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0132 0.0058 0.0634
Echinococcus granulosus cyclin B 0.005 0.0014 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.1232 0.0656 0.7121
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0348 0.0176 0.172
Schistosoma mansoni cpg binding protein 0.0223 0.0108 0.026
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0694 0.0363 0.5446
Plasmodium vivax vivapain-2 0.0043 0.001 0.0469
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0053 0.0016 0.0154
Entamoeba histolytica hypothetical protein 0.0242 0.0118 0.1131
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0102 0.0042 0.2198
Loa Loa (eye worm) hypothetical protein 0.0152 0.0069 0.067
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0027 0.0002 0.0013
Plasmodium falciparum replication factor C subunit 1, putative 0.0132 0.0058 0.308
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0141 0.0064 0.0064
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0011
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0016 0.0174
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0044 0.0011 0.0012
Trypanosoma brucei Aminopeptidase M1, putative 0.0042 0.001 0.0124
Schistosoma mansoni inositol monophosphatase 0.0045 0.0011 0.0024
Echinococcus granulosus carboxylesterase 5A 0.01 0.0041 0.0048
Brugia malayi hypothetical protein 0.0061 0.002 0.0192
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.0005 0.0006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0009 0.0082
Trypanosoma brucei DNA polymerase IV, putative 0.0101 0.0041 0.0602
Onchocerca volvulus 0.0043 0.001 0.0094
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0011 0.009
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0295 0.0147 0.0355
Leishmania major NADH dehydrogenase, putative 0.0027 0.0002 0.0004
Echinococcus granulosus acetylcholinesterase 0.01 0.0041 0.0048
Leishmania major endonuclease/exonuclease protein-like protein 0.0029 0.0002 0.0007
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Brugia malayi glutamate synthase 0.0027 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0298 0.0149 0.1438
Loa Loa (eye worm) hypothetical protein 0.017 0.0079 0.0763
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0003 0.012
Schistosoma mansoni tar DNA-binding protein 0.0521 0.0269 0.0654
Loa Loa (eye worm) TAR-binding protein 0.0521 0.0269 0.2604
Schistosoma mansoni fkbp-rapamycin associated protein 0.0678 0.0355 0.0863
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0006 0.0007
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0004 0.0004
Echinococcus granulosus phosphoglycerate kinase 1 0.019 0.009 0.0104
Schistosoma mansoni phosphoglycerate kinase 0.019 0.009 0.0216
Echinococcus granulosus apoptotic protease activating factor 1 0.005 0.0014 0.0016
Leishmania major pyruvate kinase 0.0105 0.0044 0.0139
Brugia malayi Cyclin, N-terminal domain containing protein 0.005 0.0014 0.0138
Loa Loa (eye worm) latrophilin receptor protein 2 0.026 0.0128 0.1235
Trypanosoma brucei PAB1-binding protein , putative 0.0161 0.0074 0.1092
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0061 0.002 0.0192
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0027 0.0002 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0141 0.0064 0.0211
Echinococcus multilocularis cysteine protease 0.0043 0.001 0.001
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0005 0.0035
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0008 0.0091
Schistosoma mansoni Smad4 0.004 0.0009 0.0019
Entamoeba histolytica acyl-CoA synthetase, putative 0.0493 0.0254 0.2449
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0132 0.0058 0.1462
Echinococcus granulosus tumor protein p63 0.4371 0.2358 0.2734
Echinococcus granulosus pyruvate kinase 0.0054 0.0016 0.0019
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0102 0.0042 0.0621
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0037 0.0007 0.017
Brugia malayi hypothetical protein 0.0132 0.0058 0.0564
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0105 0.0044 0.0426
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0141 0.0064 0.0615
Trypanosoma brucei metacaspase 5, putative 0.0053 0.0016 0.0216
Mycobacterium tuberculosis Probable exported protein 0.0029 0.0002 0.0021
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0102 0.0042 0.1082
Brugia malayi AMP-binding enzyme family protein 0.0145 0.0065 0.0632
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0818 0.0431 0.0431
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0082 0.0032 0.0074
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0004 0.0007
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.2579 0.1386 0.1607
Mycobacterium ulcerans DNA polymerase IV 0.0101 0.0041 0.1069
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0042 0.001 0.0106
Leishmania major DNA polymerase eta, putative 0.0047 0.0013 0.004
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0102 0.0042 0.2187
Echinococcus multilocularis pyruvate kinase 0.0054 0.0016 0.0016
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0139
Schistosoma mansoni hypothetical protein 0.005 0.0014 0.0031
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0029 0.0002 0.0061
Brugia malayi Hemopexin family protein 0.0768 0.0403 0.39
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0002 0.0004
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0029 0.0002 0.0011
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0016 0.0016
Schistosoma mansoni Smad4 0.004 0.0009 0.0019
Echinococcus granulosus neuroligin 0.0045 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0073 0.0026 0.0256
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0016 0.022
Onchocerca volvulus 0.0043 0.001 0.0094
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0003 0.0038
Treponema pallidum NADH oxidase 0.0102 0.0042 0.1325
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0298 0.0149 0.036
Echinococcus multilocularis TGF beta signal transducer SmadC 0.009 0.0036 0.0036
Echinococcus granulosus Niemann Pick C1 protein 0.193 0.1034 0.1199
Trypanosoma cruzi cysteine proteinase, putative 0.0033 0.0005 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0029 0.0002 0.0007
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0029 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0018 0.0248
Echinococcus multilocularis microtubule associated protein 2 0.7586 0.4103 0.4103
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0005 0.0047
Onchocerca volvulus 0.0117 0.005 0.0509
Echinococcus granulosus Smad4 0.009 0.0036 0.0042
Treponema pallidum DNA ligase (lig) 0.0132 0.0058 0.186
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0048 0.0153
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0029 0.0002 0.0047
Brugia malayi Niemann-Pick C1 protein precursor 0.193 0.1034 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0044 0.0422
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0002 0.0015
Plasmodium falciparum DNase I-like protein, putative 0.0029 0.0002 0.0061
Plasmodium falciparum metacaspase-like protein 0.0053 0.0016 0.0789
Brugia malayi 6-phosphofructokinase 0.0113 0.0048 0.0467
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Onchocerca volvulus 0.0042 0.001 0.0089
Brugia malayi Pre-SET motif family protein 0.0221 0.0107 0.1032
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0242 0.0118 0.0392
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0124 0.0054 0.0054
Mycobacterium tuberculosis Probable hydrolase 0.0298 0.0149 0.1455
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0004 0.0147
Brugia malayi MH1 domain containing protein 0.005 0.0014 0.0136
Mycobacterium ulcerans hypothetical protein 0.0027 0.0002 0.0034
Echinococcus granulosus tar DNA binding protein 0.0521 0.0269 0.0312
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0477 0.0246 0.0783
Mycobacterium tuberculosis Probable lipase LipD 0.0298 0.0149 0.1455
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0027 0.0002 0.0003
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0141 0.0064 0.0935
Trypanosoma brucei polo-like protein kinase 0.0477 0.0246 0.3674
Echinococcus granulosus cysteine protease 0.0033 0.0005 0.0006
Trypanosoma brucei Metacaspase-4 0.0053 0.0016 0.0216
Brugia malayi Latrophilin receptor protein 2 0.026 0.0128 0.1235
Loa Loa (eye worm) patched family protein 0.0117 0.005 0.0487
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0074 0.0027 0.0086
Brugia malayi MH1 domain containing protein 0.005 0.0014 0.0136
Trichomonas vaginalis Phospholipase C precursor, putative 0.0029 0.0002 0.0026
Echinococcus multilocularis L aminoadipate semialdehyde 0.017 0.0079 0.0079
Brugia malayi cytochrome P450 0.0037 0.0007 0.0065
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0046 0.0449
Trichomonas vaginalis cyclin A, putative 0.005 0.0014 0.0155
Brugia malayi Carboxylesterase family protein 0.0045 0.0011 0.011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0298 0.0149 0.036
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0141 0.0064 0.0935
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0012 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0115 0.0049 0.0049
Schistosoma mansoni acetylcholinesterase 0.0045 0.0011 0.0025
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0003 0.0106
Echinococcus granulosus mothers against decapentaplegic 2 0.004 0.0009 0.001
Loa Loa (eye worm) phosphatidylinositol 3 0.0242 0.0118 0.1141
Brugia malayi orphan nuclear receptor NR2E1 0.0054 0.0016 0.0158
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0493 0.0254 0.6576
Mycobacterium ulcerans aminopeptidase N PepN 0.0042 0.001 0.0247
Leishmania major cathepsin L-like protease 0.0043 0.001 0.0032
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0102 0.0042 0.0042
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0074 0.0027 0.0263
Toxoplasma gondii propionate-CoA ligase 0.0145 0.0065 0.098
Plasmodium vivax pyruvate kinase 2, putative 0.0054 0.0016 0.0783
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0029 0.0002 0.0023
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0145 0.0065 0.0639
Trypanosoma cruzi metacaspase, putative 0.0053 0.0016 0.0052
Entamoeba histolytica protein kinase rad3, putative 0.0678 0.0355 0.3424
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0013 0.017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0013 0.0136
Loa Loa (eye worm) hypothetical protein 0.0061 0.002 0.0192
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0042 0.001 0.001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0368 0.0187 0.4826
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0242 0.0118 0.0285
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0048 0.0471
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Leishmania major phosphatidylinositol kinase related protein, putative 0.0257 0.0126 0.0402
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0156 0.1696
Loa Loa (eye worm) hypothetical protein 0.0368 0.0187 0.1804
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0037 0.0007 0.0064
Toxoplasma gondii isocitrate dehydrogenase 0.0114 0.0049 0.0725
Trypanosoma cruzi aminopeptidase, putative 0.0042 0.001 0.0032
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0007
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0011 0.0144
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0221 0.0107 0.0257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0073 0.0027 0.0258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0002 0.0023
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0141 0.0064 0.7026
Trypanosoma brucei DNA polymerase IV, putative 0.0101 0.0041 0.0602
Schistosoma mansoni netrin receptor unc5 0.0029 0.0002 0.0003
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0678 0.0355 0.1182
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0115 0.0049 0.0477
Leishmania major hypothetical protein, conserved 0.0027 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0132 0.0058 0.0564
Brugia malayi hypothetical protein 0.0117 0.005 0.0487
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0361 0.0183 0.1987
Loa Loa (eye worm) oxidoreductase 0.0145 0.0065 0.0632
Loa Loa (eye worm) hypothetical protein 0.0103 0.0043 0.0415
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0025 0.0078
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0533 0.0276 0.0276
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0027 0.0002 0.0002
Schistosoma mansoni glutamate synthase 0.0027 0.0002 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0082 0.0032 0.0074
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0027 0.0027
Leishmania major phosphoglycerate kinase B, cytosolic 0.019 0.009 0.0286
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.043 0.022 0.2154
Leishmania major 4-coumarate:coa ligase-like protein 0.0493 0.0254 0.081
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0005 0.0033
Loa Loa (eye worm) jmjC domain-containing protein 0.0132 0.0058 0.0565
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1243 0.0661 0.2202
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0493 0.0254 0.6576
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0323 0.0162 0.0539
Brugia malayi MH1 domain containing protein 0.009 0.0036 0.0348
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0177 0.0083 0.0083
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0115 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0023
Brugia malayi Nuclear hormone receptor E75 0.0054 0.0016 0.0158
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0115 0.0049 0.0057
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0678 0.0355 0.3432
Brugia malayi Carboxylesterase family protein 0.01 0.0041 0.04
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0029 0.0002 0.0023
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0055 0.0017 0.0425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0796 0.0419 0.4548
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0042 0.001 0.0011
Leishmania major hypothetical protein, conserved 0.58 0.3133 1
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0027 0.0002 0.0001
Trichomonas vaginalis spcc417.12 protein, putative 0.0045 0.0011 0.0123
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Toxoplasma gondii LsmAD domain-containing protein 0.0161 0.0074 0.1113
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0003 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.0298 0.0149 0.1455
Schistosoma mansoni rab6-interacting 0.0121 0.0053 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0139
Brugia malayi ImpB/MucB/SamB family protein 0.0098 0.004 0.0387
Brugia malayi hypothetical protein 0.0054 0.0016 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.01 0.0041 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0054 0.0016 0.0019
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0042 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trypanosoma cruzi cysteine protease, putative 0.0033 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Schistosoma mansoni smad 0.009 0.0036 0.0085
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0044 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.1459 0.0778 0.7528
Loa Loa (eye worm) ctsf protein 0.0043 0.001 0.0099
Brugia malayi hypothetical protein 0.0132 0.0058 0.0564
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0027 0.0002 0.0002
Plasmodium vivax vivapain-2 0.0043 0.001 0.0469
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Mycobacterium ulcerans ferredoxin reductase 0.0027 0.0002 0.0034
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0242 0.0118 0.0392
Brugia malayi Peptidase family M1 containing protein 0.0042 0.001 0.0094
Mycobacterium tuberculosis Probable oxidoreductase 0.0743 0.039 0.3821
Brugia malayi Patched related family protein 12 0.0117 0.005 0.0487
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0361 0.0183 0.1769
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0098 0.0999
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0037 0.0007 0.0064
Mycobacterium ulcerans DNA polymerase IV 0.0101 0.0041 0.1069
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0054 0.0016 0.0157
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0042 0.001 0.003
Schistosoma mansoni thyroid hormone receptor 0.0239 0.0116 0.0281
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0048 0.0455
Onchocerca volvulus Protein ultraspiracle homolog 0.0115 0.0049 0.0497
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0115 0.0049 0.0057
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0463 0.0238 0.0238
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.069 0.0361 0.3483
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.026 0.0128 0.0148
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0013 0.0621
Trichomonas vaginalis phosphoglycerate kinase, putative 0.019 0.009 0.0977
Plasmodium vivax hypothetical protein 0.0242 0.0118 0.6296
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0048 0.0467
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0027 0.0002 0.0034
Onchocerca volvulus 0.0242 0.0118 0.1207
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0045 0.0011 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.1214 0.0646 0.7012
Schistosoma mansoni hypothetical protein 0.0798 0.042 0.1021
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0054 0.0016 0.0016
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Toxoplasma gondii patched family protein 0.0117 0.005 0.075
Leishmania major hypothetical protein, conserved 0.0027 0.0002 0.0004
Echinococcus multilocularis neutral sphingomyelinase 0.0029 0.0002 0.0002
Echinococcus granulosus geminin 0.2413 0.1296 0.1503
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.059 0.0307 0.296
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0103 0.0341
Loa Loa (eye worm) aminopeptidase N 0.0042 0.001 0.0094
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0242 0.0118 0.0118
Entamoeba histolytica cysteine proteinase 2 0.0033 0.0005 0.0035
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.026 0.0128 0.0148
Echinococcus granulosus caspase 2 0.0103 0.0043 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0237 0.0116 0.0279
Loa Loa (eye worm) hypothetical protein 0.0053 0.0016 0.0154
Trypanosoma brucei phosphoglycerate kinase 0.019 0.009 0.1331
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0139
Brugia malayi Glycosyl hydrolases family 31 protein 0.0117 0.005 0.0488
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0649 0.0339 0.3281
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0002 0.0004
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Brugia malayi MH2 domain containing protein 0.004 0.0009 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Brugia malayi jmjC domain containing protein 0.0032 0.0004 0.0039
Schistosoma mansoni aldehyde dehydrogenase 0.043 0.022 0.0534
Giardia lamblia Fructose-bisphosphate aldolase 0.059 0.0307 0.4599
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0145 0.0065 0.0961
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Brugia malayi Bromodomain containing protein 0.0041 0.0009 0.009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0451 0.0231 0.0562
Echinococcus multilocularis thioredoxin glutathione reductase 0.0295 0.0147 0.0147
Loa Loa (eye worm) acetyltransferase 0.0177 0.0083 0.0804
Schistosoma mansoni hypothetical protein 0.0768 0.0403 0.0981
Plasmodium vivax SET domain protein, putative 0.0221 0.0107 0.5685
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0668 0.035 0.3425
Brugia malayi Isocitrate dehydrogenase 0.0114 0.0049 0.0472
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0029 0.0002 0.0047
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0004 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0074 0.0027 0.0694
Schistosoma mansoni synaptojanin 0.0029 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0237 0.0116 0.1119
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0037 0.0007 0.0022
Leishmania major hypothetical protein, conserved 0.0032 0.0004 0.0012
Trypanosoma brucei phosphoglycerate kinase 0.019 0.009 0.1331
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5919 0.8624 0.8624
Brugia malayi Pyruvate kinase, muscle isozyme 0.0105 0.0044 0.0422
Brugia malayi Nuclear hormone receptor E75 0.0054 0.0016 0.0158
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0237 0.0116 0.0116
Onchocerca volvulus 0.0117 0.005 0.0509
Loa Loa (eye worm) patched family protein 0.0117 0.005 0.0487
Mycobacterium ulcerans acyl-CoA synthetase 0.0493 0.0254 0.6576
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Loa Loa (eye worm) MH1 domain-containing protein 0.009 0.0036 0.0348
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0073 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0583 0.0303 0.2924
Onchocerca volvulus 0.0493 0.0254 0.2613
Toxoplasma gondii ATPase, AAA family protein 0.0132 0.0058 0.0872
Echinococcus granulosus cathepsin l cysteine peptidase 0.0043 0.001 0.0012
Brugia malayi Cathepsin L-like precursor 0.0043 0.001 0.0099
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0002 0.0003
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0242 0.0118 0.6301
Trypanosoma brucei phosphoglycerate kinase, putative 0.007 0.0025 0.0349
Echinococcus multilocularis GPCR, family 2 0.026 0.0128 0.0128
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0011 0.012
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0027 0.0002 0.0016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0124 0.0054 0.0129
Loa Loa (eye worm) cysteine protease 0.0043 0.001 0.0099
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0132 0.0058 0.0634
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0512 0.0265 0.0265
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0037 0.0007 0.0064
Trypanosoma cruzi trypanothione reductase, putative 0.0293 0.0146 0.0485
Schistosoma mansoni caspase-7 (C14 family) 0.0141 0.0064 0.0152
Schistosoma mansoni chromosome transmission fidelity factor 0.0132 0.0058 0.0139
Onchocerca volvulus 0.0145 0.0065 0.0663
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0145 0.0065 0.1687
Loa Loa (eye worm) hypothetical protein 0.0037 0.0007 0.0068
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0044 0.0011 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0018 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0493 0.0254 0.2489
Schistosoma mansoni neutral sphingomyelinase 0.0029 0.0002 0.0003
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0029 0.0002 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Echinococcus multilocularis traf and tnf receptor associated protein 0.0029 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0042 0.001 0.0011
Trichomonas vaginalis cyclins, putative 0.005 0.0014 0.0155
Toxoplasma gondii histone lysine methyltransferase SET1 0.041 0.0209 0.319
Loa Loa (eye worm) hypothetical protein 0.0061 0.002 0.0192
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0074 0.0027 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0115 0.0049 0.0477
Entamoeba histolytica aminopeptidase, putative 0.0042 0.001 0.0082
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0512 0.0265 0.0307
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0029 0.0002 0.0061
Mycobacterium ulcerans NADH dehydrogenase 0.0027 0.0002 0.0034
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0029 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0005 0.0048
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0016 0.022
Echinococcus multilocularis nibrin 0.0132 0.0058 0.0058
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0145 0.0065 0.0639
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0054 0.0016 0.0158
Loa Loa (eye worm) carboxylesterase 0.0045 0.0011 0.011
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0054 0.0016 0.0037
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0032 0.0004 0.0039
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0114 0.0049 0.0057
Leishmania major 4-coumarate:coa ligase-like protein 0.0493 0.0254 0.081
Onchocerca volvulus 0.0045 0.0011 0.0105
Toxoplasma gondii cathepsin CPL 0.0043 0.001 0.0133
Loa Loa (eye worm) pyruvate kinase 0.0105 0.0044 0.0422
Echinococcus granulosus Nuclear hormone receptor HR96 0.0054 0.0016 0.0019
Echinococcus multilocularis acetylcholinesterase 0.01 0.0041 0.0041
Trichomonas vaginalis esterase, putative 0.0298 0.0149 0.1615
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0115 0.0049 0.0477
Echinococcus granulosus caspase 3 0.0088 0.0035 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0298 0.0149 0.0494
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0003 0.0021
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0002 0.0001
Plasmodium falciparum glutathione reductase 0.0102 0.0042 0.2198
Brugia malayi isocitrate dehydrogenase 0.0114 0.0049 0.0472
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0037 0.0007 0.0064
Mycobacterium leprae Conserved hypothetical protein 0.0037 0.0007 0.0135
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0054 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.0115 0.1248
Echinococcus granulosus GPCR family 2 0.026 0.0128 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.0115 0.1248
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0828 0.0436 0.4219
Echinococcus granulosus aminopeptidase N 0.0042 0.001 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0242 0.0118 0.6296
Trichomonas vaginalis pyruvate kinase, putative 0.0105 0.0044 0.0474
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0007
Echinococcus multilocularis Niemann Pick C1 protein 0.193 0.1034 0.1034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Echinococcus granulosus Nuclear hormone receptor HR96 0.0054 0.0016 0.0019
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0011 0.1083
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1243 0.0661 0.2202
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0027 0.0002 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0221 0.0107 0.0107
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0145 0.0065 0.0639
Toxoplasma gondii exonuclease III APE 0.0141 0.0064 0.0953
Onchocerca volvulus 0.0117 0.005 0.0509
Brugia malayi jmjC domain containing protein 0.0032 0.0004 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Echinococcus granulosus BC026374 protein S09 family 0.0045 0.0011 0.0013
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0011
Echinococcus granulosus Niemann Pick C1 protein 0.2758 0.1483 0.172
Echinococcus multilocularis pyruvate kinase 0.0105 0.0044 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Echinococcus multilocularis neutral alpha glucosidase AB 0.0117 0.005 0.005
Onchocerca volvulus 0.1721 0.0921 0.9495
Leishmania major cyclin 0.005 0.0014 0.0045
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0013 0.0173
Chlamydia trachomatis DNA ligase 0.0132 0.0058 0.307
Loa Loa (eye worm) hypothetical protein 0.0828 0.0436 0.4219
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.0436 0.4739
Schistosoma mansoni transcription factor LCR-F1 0.0782 0.0411 0.0999
Schistosoma mansoni alpha-glucosidase 0.0454 0.0233 0.0566
Trypanosoma brucei metacaspase MCA3 0.0053 0.0016 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.1214 0.0646 0.7012
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0025 0.0082
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0132 0.0058 0.0855
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0002 0.0004
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0042 0.001 0.0011
Schistosoma mansoni topbp1 0.0132 0.0058 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.069 0.0361 0.3921
Echinococcus granulosus traf and tnf receptor associated protein 0.0029 0.0002 0.0003
Onchocerca volvulus 0.0221 0.0107 0.109
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0279 0.0138 0.2057
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0029 0.0002 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0477 0.0246 0.2667
Loa Loa (eye worm) MH2 domain-containing protein 0.009 0.0036 0.0348
Onchocerca volvulus 0.0043 0.001 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0361 0.0183 0.1987
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0298 0.0148 0.1435
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0295 0.0147 0.0468
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0061 0.002 0.0023
Mycobacterium tuberculosis Probable lipase LipE 0.0298 0.0149 0.1455
Entamoeba histolytica phosphoglycerate kinase, putative 0.019 0.009 0.0858
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0037 0.0007 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.0246 0.0596
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0003 0.0106
Schistosoma mansoni phosphoglycerate kinase 0.019 0.009 0.0216
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0145 0.0065 0.1687
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Trypanosoma cruzi cysteine peptidase, putative 0.01 0.0041 0.0136
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0102 0.0042 0.2187
Trichomonas vaginalis antibiotic synthetase, putative 0.0145 0.0065 0.071
Brugia malayi Thioredoxin reductase 0.0293 0.0146 0.1411
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0037 0.0007 0.0064
Leishmania major hypothetical protein, conserved 0.0161 0.0074 0.0236
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0029 0.0002 0.0007
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0004 0.0007
Trypanosoma cruzi cyclin, putative 0.005 0.0014 0.0047
Leishmania major 4-coumarate:coa ligase-like protein 0.0493 0.0254 0.081
Plasmodium falciparum glutathione reductase 0.0293 0.0146 0.7804
Brugia malayi Pax transcription activation domain interacting protein 0.0132 0.0058 0.0564
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0042 0.001 0.001
Plasmodium vivax unspecified product 0.0209 0.01 0.5332
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.1191 0.0633 0.6875
Leishmania major cathepsin L-like protease 0.0043 0.001 0.0032
Plasmodium vivax JmjC domain containing protein 0.0032 0.0004 0.0133
Loa Loa (eye worm) hypothetical protein 0.0493 0.0254 0.2458
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0029 0.0002 0.0026
Echinococcus multilocularis zinc finger protein 0.0035 0.0006 0.0006
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0005 0.0048
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0002 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0037 0.0007 0.0064
Brugia malayi Carboxylesterase family protein 0.0045 0.0011 0.011
Plasmodium vivax hypothetical protein, conserved 0.0298 0.0149 0.795
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0288 0.0143 0.3703
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0463 0.0238 0.0276
Trypanosoma cruzi cysteine peptidase, putative 0.0043 0.001 0.0033
Brugia malayi hypothetical protein 0.0161 0.0074 0.0716
Loa Loa (eye worm) hypothetical protein 0.0921 0.0487 0.4708
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0011 0.0115
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0048 0.0056
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0007
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0242 0.0118 0.1754
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Schistosoma mansoni niemann-pick C1 (NPC1) 0.196 0.105 0.2558
Echinococcus multilocularis lysine specific demethylase 5A 0.0118 0.0051 0.0051
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0114 0.0049 0.0712
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0003 0.0038
Trypanosoma cruzi cruzipain precursor, putative 0.01 0.0041 0.0136
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0694 0.0363 0.0883
Echinococcus granulosus dnaJ subfamily B 0.2577 0.1385 0.1606
Echinococcus granulosus mixed lineage leukemia protein mll 0.006 0.0019 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.005 0.0167
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0145 0.0065 0.0639
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0102 0.0042 0.0609
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0037 0.0007 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Echinococcus multilocularis caspase 2 0.0103 0.0043 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0013 0.0136
Mycobacterium ulcerans glutamate synthase subunit beta 0.0027 0.0002 0.0034
Brugia malayi Pre-SET motif family protein 0.1513 0.0808 0.781
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.026 0.0128 0.1235
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1243 0.0661 0.1609
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0048 0.0013 0.0325
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0124 0.0054 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.005 0.0167
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Toxoplasma gondii thioredoxin reductase 0.0293 0.0146 0.2216
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0115 0.0049 0.0477
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0117 0.005 0.0476
Schistosoma mansoni caspase-3 (C14 family) 0.0141 0.0064 0.0152
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0013 0.0169
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0102 0.0042 0.0609
Schistosoma mansoni rab6-interacting 0.0121 0.0053 0.0126
Schistosoma mansoni gliotactin 0.0045 0.0011 0.0025
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0027 0.0002 0.0013
Schistosoma mansoni glutamate synthase 0.0027 0.0002 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0027 0.0258
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0102 0.0042 0.2187
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0012 0.0151
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0029 0.0002 0.0002
Onchocerca volvulus 0.0117 0.005 0.0509
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1251 0.0666 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0145 0.0065 0.0639
Toxoplasma gondii melibiase subfamily protein 0.0124 0.0054 0.0806
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0072 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Echinococcus granulosus ecdysone induced protein 78C 0.0115 0.0049 0.0057
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0044 0.0011 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0242 0.0118 0.1141
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0002 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.043 0.022 0.022
Mycobacterium ulcerans glutaminase 0.0278 0.0138 0.3557
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0117 0.005 0.0548
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0477 0.0246 0.2374
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0242 0.0118 0.1754
Brugia malayi hypothetical protein 0.0117 0.005 0.0487
Schistosoma mansoni terminal deoxycytidyl transferase 0.0073 0.0027 0.0062
Trypanosoma brucei pyruvate kinase 1, putative 0.0105 0.0044 0.0634
Onchocerca volvulus 0.0605 0.0315 0.324
Loa Loa (eye worm) hypothetical protein 0.0122 0.0053 0.0511
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0132 0.0058 0.0194
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0114 0.0049 0.0049
Echinococcus granulosus thioredoxin glutathione reductase 0.0295 0.0147 0.017
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0002 0.0003
Brugia malayi Patched protein homolog 1 0.0117 0.005 0.0487
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Schistosoma mansoni thyroid hormone receptor 0.0239 0.0116 0.0281
Schistosoma mansoni zinc finger protein 0.0035 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Treponema pallidum fructose-bisphosphate aldolase 0.059 0.0307 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0037 0.0007 0.017
Leishmania major hypothetical protein, conserved 0.0298 0.0149 0.0474
Echinococcus multilocularis pyruvate kinase 0.0083 0.0032 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0053 0.0016 0.0776
Trichomonas vaginalis alpha-glucosidase, putative 0.0117 0.005 0.0548
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0141 0.0064 0.0074
Entamoeba histolytica deoxycytidyl transferase, putative 0.0073 0.0027 0.0246
Plasmodium vivax phosphoglycerate kinase, putative 0.019 0.009 0.4776
Loa Loa (eye worm) matrix metalloproteinase 0.0605 0.0315 0.3045
Leishmania major hypothetical protein, conserved 0.0029 0.0002 0.0007
Leishmania major cytochrome p450-like protein 0.0037 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0027
Giardia lamblia Hypothetical protein 0.0242 0.0118 0.1754
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0027 0.0002 0.0014
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0102 0.0042 0.0406
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0295 0.0147 0.141
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0003 0.0106
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0075 0.0027 0.0265
Trichomonas vaginalis cyclins, putative 0.005 0.0014 0.0155
Brugia malayi nuclear hormone receptor family member odr-7 0.0054 0.0016 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.1251 0.0666 0.7231
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0002 0.0002
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.012 0.0052 0.0172
Brugia malayi protein C24B5.3 0.0117 0.005 0.0487
Leishmania major acetyl-CoA synthetase, putative 0.0145 0.0065 0.0208
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0007
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0437 0.0224 0.2167
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0115 0.0049 0.0117
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.0086 0.0875
Loa Loa (eye worm) hypothetical protein 0.0061 0.002 0.0192
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0002 0.0003
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0295 0.0147 0.1421
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Brugia malayi Matrixin family protein 0.0605 0.0315 0.3045
Brugia malayi Myosin head containing protein 0.0117 0.005 0.0487
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0012 0.0109
Onchocerca volvulus 0.0029 0.0002 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.5558 0.3002 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Onchocerca volvulus 0.0117 0.005 0.0509
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0025 0.0082
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0132 0.0058 0.1505
Loa Loa (eye worm) STAT protein 0.0159 0.0073 0.0707
Trichomonas vaginalis alpha-glucosidase, putative 0.0117 0.005 0.0548
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0037 0.0007 0.017
Leishmania major phosphoglycerate kinase C, glycosomal 0.019 0.009 0.0286
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0361 0.0183 0.1759
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0141 0.0064 0.0604
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0048 0.0455
Schistosoma mansoni jumonji/arid domain-containing protein 0.0132 0.0058 0.014
Brugia malayi TAR-binding protein 0.0521 0.0269 0.2604
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0017
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0242 0.0118 0.6301
Entamoeba histolytica hypothetical protein 0.0782 0.0411 0.3967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0715 0.0375 0.4074
Brugia malayi photoreceptor-specific nuclear receptor 0.0115 0.0049 0.0477
Loa Loa (eye worm) MH1 domain-containing protein 0.004 0.0009 0.0085
Schistosoma mansoni kinase 0.0242 0.0118 0.0286
Echinococcus multilocularis apoptotic protease activating factor 1 0.005 0.0014 0.0014
Onchocerca volvulus Cathepsin F homolog 0.0043 0.001 0.0094
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0141
Leishmania major cathepsin L-like protease 0.0043 0.001 0.0032
Loa Loa (eye worm) phosphatidylinositol 3 0.0242 0.0118 0.1141
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0037 0.0007 0.017
Onchocerca volvulus 0.0045 0.0011 0.0105
Brugia malayi Matrixin family protein 0.0605 0.0315 0.3045
Onchocerca volvulus Protein patched homolog 0.0117 0.005 0.0509
Brugia malayi jmjC domain containing protein 0.0032 0.0004 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.001 0.0111
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0013 0.0136
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0548 0.0284 0.3085
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0348 0.0176 0.172
Echinococcus granulosus sterol regulatory element binding protein 0.0828 0.0436 0.0506
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0361 0.0183 0.0609
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0103 0.0341
Loa Loa (eye worm) hypothetical protein 0.0132 0.0058 0.0564
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0069 0.0069
Echinococcus multilocularis adam 17 protease 0.155 0.0828 0.0828
Onchocerca volvulus 0.0117 0.005 0.0509
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0141 0.0064 0.0691
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0002 0.0016
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0042 0.001 0.003
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0242 0.0118 0.0285
Schistosoma mansoni nuclear receptor 0.0054 0.0016 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Loa Loa (eye worm) patched family protein 0.0117 0.005 0.0487
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Schistosoma mansoni bromodomain containing protein 0.0077 0.0029 0.0068
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0115 0.0049 0.0057
Trypanosoma brucei hypothetical protein, conserved 0.0213 0.0103 0.1522
Echinococcus multilocularis expressed conserved protein 0.1813 0.0971 0.0971
Brugia malayi Cathepsin L-like precursor 0.0043 0.001 0.0099
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0242 0.0118 0.1141
Loa Loa (eye worm) hypothetical protein 0.005 0.0014 0.0138
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0037 0.0007 0.0064
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0037 0.0007 0.0021
Trichomonas vaginalis cyclin B, putative 0.005 0.0014 0.0155
Loa Loa (eye worm) hypothetical protein 0.0561 0.0291 0.2815
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0002 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0041 0.0137
Brugia malayi hypothetical protein 0.0921 0.0487 0.4708
Echinococcus granulosus nuclear receptor nhr 48 0.0054 0.0016 0.0019
Brugia malayi Peptidase family M1 containing protein 0.0042 0.001 0.0094
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.1075 0.057 0.1387
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0002 0.0015
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0037 0.0007 0.0064
Brugia malayi Smad1 0.009 0.0036 0.0348
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0153 0.007 0.1028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0013 0.0136
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0082 0.0032 0.0344
Brugia malayi Uncoordinated protein 44 0.0029 0.0002 0.0023
Entamoeba histolytica hypothetical protein 0.0048 0.0013 0.0111
Schistosoma mansoni lamin 0.011 0.0046 0.011
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Echinococcus granulosus L aminoadipate semialdehyde 0.017 0.0079 0.0091
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0013 0.004
Trypanosoma brucei metacaspase MCA2 0.0053 0.0016 0.0216
Plasmodium vivax multidomain scavenger receptor, putative 0.0121 0.0053 0.277
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0295 0.0147 0.0355
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0017 0.0161
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0668 0.035 0.3425
Trichomonas vaginalis rotamase, putative 0.0033 0.0005 0.0055
Schistosoma mansoni BC026374 protein (S09 family) 0.0045 0.0011 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Plasmodium falciparum ataxin-2 like protein, putative 0.0161 0.0074 0.3926
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0016 0.0223
Trypanosoma cruzi Aminopeptidase M1, putative 0.0042 0.001 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.1209 0.0643 0.6984
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.0156 0.151
Leishmania major hypothetical protein, conserved 0.0027 0.0002 0.0004
Leishmania major glycosyl hydrolase-like protein 0.0044 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0023
Trichomonas vaginalis cyclins, putative 0.005 0.0014 0.0155
Onchocerca volvulus 0.0145 0.0065 0.0663
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0041 0.0137
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1251 0.0666 0.6433
Onchocerca volvulus Bile acid receptor homolog 0.0115 0.0049 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Schistosoma mansoni carbon catabolite repressor protein 0.0029 0.0002 0.0003
Trichomonas vaginalis cyclins, putative 0.005 0.0014 0.0155
Echinococcus granulosus glutamate synthase 0.0027 0.0002 0.0002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0002 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.1459 0.0778 0.0778
Onchocerca volvulus Huntingtin homolog 0.0135 0.006 0.061
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0179 0.0084 0.0813
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0102 0.0042 0.1082
Trichomonas vaginalis phosphoglycerate kinase, putative 0.019 0.009 0.0977
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0014 0.0189
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0027 0.0002 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0042 0.001 0.001
Brugia malayi DKFZp564C0469 protein 0.0132 0.0058 0.0564
Echinococcus multilocularis caspase 8 0.0053 0.0016 0.0016
Loa Loa (eye worm) fibroinase 0.0043 0.001 0.0099
Brugia malayi SET domain containing protein 0.0026 0.0001 0.0011
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0117 0.005 0.0476
Echinococcus granulosus lipoxygenase domain containing protein 0.0121 0.0053 0.0061
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0045 0.0011 0.0013
Schistosoma mansoni cpg binding protein 0.0209 0.01 0.0241
Plasmodium vivax thioredoxin reductase, putative 0.0293 0.0146 0.78
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0003 0.0106
Echinococcus granulosus mothers against decapentaplegic 6 0.004 0.0009 0.001
Schistosoma mansoni intermediate filament proteins 0.011 0.0046 0.011
Brugia malayi hypothetical protein 0.0437 0.0224 0.2167
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0037 0.0007 0.0064
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1513 0.0808 0.781
Schistosoma mansoni hypothetical protein 0.0242 0.0118 0.0285
Loa Loa (eye worm) hypothetical protein 0.0493 0.0254 0.2458
Trypanosoma cruzi cysteine proteinase, putative 0.0033 0.0005 0.0016
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0011 0.0102
Echinococcus granulosus cathepsin L cysteine proteinase 0.0043 0.001 0.0012
Schistosoma mansoni smad1 5 8 and 0.009 0.0036 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0298 0.0149 0.2216
Brugia malayi hypothetical protein 0.0121 0.0053 0.051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0115 0.0049 0.0477
Trypanosoma cruzi phosphoglycerate kinase, putative 0.019 0.009 0.0299
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0361 0.0183 0.2732
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Loa Loa (eye worm) hypothetical protein 0.0186 0.0088 0.085
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1251 0.0666 0.0772
Echinococcus granulosus dna polymerase kappa 0.0101 0.0041 0.0048
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0242 0.0118 0.1141
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0172
Brugia malayi hypothetical protein 0.0045 0.0011 0.011
Plasmodium vivax vivapain-3 0.0033 0.0005 0.0182
Loa Loa (eye worm) hypothetical protein 0.0044 0.0011 0.0102
Brugia malayi Carboxylesterase family protein 0.01 0.0041 0.04
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0145 0.0065 0.1687
Echinococcus granulosus neutral alpha glucosidase AB 0.0117 0.005 0.0058
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0145 0.0065 0.0208
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0002 0.0047
Plasmodium vivax ataxin-2 like protein, putative 0.0161 0.0074 0.3917
Trichomonas vaginalis glutaminase, putative 0.0278 0.0138 0.1495
Onchocerca volvulus Pyruvate kinase homolog 0.0105 0.0044 0.0439
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.001 0.0111
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0005 0.0053
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0101 0.0041 0.0451
Loa Loa (eye worm) doublecortin family protein 0.0121 0.0053 0.051
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0002 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0117 0.005 0.0548
Echinococcus multilocularis protein dispatched 1 0.0945 0.05 0.05
Plasmodium falciparum ataxin-2 like protein, putative 0.0161 0.0074 0.3926
Mycobacterium ulcerans hypothetical protein 0.0493 0.0254 0.6576
Brugia malayi hypothetical protein 0.0117 0.005 0.0487
Plasmodium falciparum LCCL domain-containing protein 0.0121 0.0053 0.278
Brugia malayi hypothetical protein 0.0135 0.006 0.0583
Brugia malayi FAT domain containing protein 0.0512 0.0265 0.2561
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0003 0.003
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0079 0.0029 0.0097
Leishmania major DNA polymerase kappa, putative 0.008 0.003 0.0096
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.008 0.003 0.0096
Entamoeba histolytica cysteine protease, putative 0.0033 0.0005 0.0035
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0145 0.0065 0.1643
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0102 0.0042 0.2198
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Echinococcus granulosus lamin dm0 0.011 0.0046 0.0054
Echinococcus granulosus FTZ F1 alpha 0.0115 0.0049 0.0057
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0029 0.0002 0.0013
Trypanosoma cruzi FHA domain containing protein, putative 0.0132 0.0058 0.0194
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Brugia malayi latrophilin 2 splice variant baaae 0.0561 0.0291 0.2815
Trichomonas vaginalis sucrase-isomaltase, putative 0.0117 0.005 0.0548
Plasmodium vivax glutathione reductase, putative 0.0293 0.0146 0.78
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0058 0.0634
Schistosoma mansoni TGF-beta signal transducer Smad2 0.009 0.0036 0.0085
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0102 0.0042 0.01
Loa Loa (eye worm) hypothetical protein 0.0736 0.0386 0.3737
Schistosoma mansoni hypothetical protein 0.026 0.0128 0.0309
Brugia malayi Cell death protein 3 precursor 0.0103 0.0043 0.0415
Plasmodium vivax metacaspase 1, putative 0.0053 0.0016 0.0776
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Schistosoma mansoni hypothetical protein 0.2577 0.1385 0.3374
Loa Loa (eye worm) hypothetical protein 0.0145 0.0065 0.0632
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Brugia malayi tailless protein 0.0054 0.0016 0.0158
Mycobacterium ulcerans lipase LipD 0.0298 0.0149 0.3844
Plasmodium vivax patched family protein, putative 0.0117 0.005 0.2641
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0694 0.0363 0.1209
Schistosoma mansoni RAR-like nuclear receptor 0.0115 0.0049 0.0117
Plasmodium falciparum thioredoxin reductase 0.0293 0.0146 0.7804
Echinococcus granulosus intermediate filament protein 0.011 0.0046 0.0054
Schistosoma mansoni neuroligin 3 (S09 family) 0.0045 0.0011 0.0025
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Echinococcus multilocularis tumor protein p63 0.4371 0.2358 0.2358
Plasmodium falciparum metacaspase 1 0.0053 0.0016 0.0789
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0011 0.0011
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0408 0.0208 0.2003
Brugia malayi Inositol-1 0.0045 0.0011 0.0107
Echinococcus multilocularis sterol regulatory element binding protein 0.0828 0.0436 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0715 0.0375 0.4074
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0002 0.0004
Mycobacterium ulcerans beta-lactamase 0.0298 0.0149 0.3844
Echinococcus granulosus histone lysine methyltransferase setb 0.0237 0.0116 0.0134
Echinococcus multilocularis phosphoglycerate kinase 1 0.019 0.009 0.009
Schistosoma mansoni hypothetical protein 0.2413 0.1296 0.3157
Trichomonas vaginalis PIKK family atypical protein kinase 0.1191 0.0633 0.6875
Loa Loa (eye worm) hypothetical protein 0.0298 0.0149 0.1438
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0115 0.0049 0.0117
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0298 0.0149 0.1455
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0208 0.01 0.0116
Trichomonas vaginalis cyclin B, putative 0.005 0.0014 0.0155
Toxoplasma gondii hypothetical protein 0.0117 0.005 0.075
Toxoplasma gondii target of rapamycin (TOR), putative 0.1228 0.0653 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0115 0.0049 0.0477
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1251 0.0666 0.0666
Schistosoma mansoni jumonji domain containing protein 0.0118 0.0051 0.0122
Brugia malayi AMP-binding enzyme family protein 0.0493 0.0254 0.2458
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0016 0.0223
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0048 0.1203
Trichomonas vaginalis PIKK family atypical protein kinase 0.1251 0.0666 0.7231
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0102 0.0042 0.4578
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0037 0.0007 0.0064
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0003 0.003
Loa Loa (eye worm) steroid hormone receptor 0.0115 0.0049 0.0477
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0102 0.0042 0.0609
Brugia malayi Phosphoglycerate kinase 0.019 0.009 0.087
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0043 0.001 0.0483
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0493 0.0254 0.6503
Brugia malayi Death domain containing protein 0.0029 0.0002 0.0023
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.001 0.001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0102 0.0042 0.0409
Echinococcus multilocularis pyruvate kinase 0.0054 0.0016 0.0016
Brugia malayi nuclear receptor NHR-88 0.0054 0.0016 0.0158
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0045 0.0011 0.0011
Trichomonas vaginalis DNA polymerase eta, putative 0.0101 0.0041 0.0451
Brugia malayi AMP-binding enzyme family protein 0.0145 0.0065 0.0632
Loa Loa (eye worm) hypothetical protein 0.0061 0.002 0.0192
Schistosoma mansoni alpha-glucosidase 0.0454 0.0233 0.0566
Schistosoma mansoni lipoxygenase 0.0726 0.0381 0.0926
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0114 0.0049 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0003 0.0038
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0114 0.0049 0.0116
Plasmodium falciparum ferrodoxin reductase-like protein 0.0027 0.0002 0.0014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0033 0.0005 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Echinococcus granulosus caspase 8 0.0053 0.0016 0.0018
Schistosoma mansoni DNA polymerase eta 0.0098 0.004 0.0095
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0533 0.0276 0.2667
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1251 0.0666 0.162
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0102 0.0042 0.0139
Toxoplasma gondii isocitrate dehydrogenase 0.0114 0.0049 0.0725
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.0156 0.151
Brugia malayi protein C24B5.3 0.0117 0.005 0.0487
Leishmania major hypothetical protein, conserved 0.0213 0.0103 0.0327
Plasmodium vivax acyl-CoA synthetase, putative 0.0368 0.0187 1
Schistosoma mansoni microtubule-associated protein tau 0.7586 0.4103 1
Brugia malayi Bromodomain containing protein 0.0089 0.0035 0.0338
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0533 0.0276 0.0276
Loa Loa (eye worm) transcription factor SMAD2 0.1327 0.0707 0.6838
Schistosoma mansoni DNA ligase IV 0.0132 0.0058 0.0139
Schistosoma mansoni hypothetical protein 0.0782 0.0411 0.0999
Loa Loa (eye worm) phosphatidylinositol kinase 0.0242 0.0118 0.1141
Trichomonas vaginalis hypothetical protein 0.0025 0.0001 0.0007
Treponema pallidum exodeoxyribonuclease (exoA) 0.0141 0.0064 0.2034
Trypanosoma brucei cytochrome P450, putative 0.0055 0.0017 0.0227
Brugia malayi Cathepsin L-like precursor 0.0043 0.001 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.1228 0.0653 0.7093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0782 0.0411 0.0477
Trichomonas vaginalis alpha-glucosidase, putative 0.0117 0.005 0.0548
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0001 0.0007
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Mycobacterium tuberculosis Conserved hypothetical protein 0.0242 0.0118 0.1155
Loa Loa (eye worm) hypothetical protein 0.0053 0.0016 0.0151
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0011 0.0115
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0003 0.0021
Echinococcus multilocularis nuclear receptor nhr 48 0.0054 0.0016 0.0016
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.002 0.0192
Brugia malayi hypothetical protein 0.0042 0.001 0.0094
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Loa Loa (eye worm) hypothetical protein 0.082 0.0432 0.4177
Brugia malayi hypothetical protein 0.0104 0.0043 0.0417
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0029 0.0002 0.0007
Brugia malayi Carboxylesterase family protein 0.0045 0.0011 0.011
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0011 0.0109
Schistosoma mansoni hypothetical protein 0.026 0.0128 0.0309
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1251 0.0666 0.2124
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0012 0.0165
Entamoeba histolytica hypothetical protein 0.0782 0.0411 0.3967
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0029 0.0002 0.0013
Trypanosoma cruzi cyclin 6, putative 0.005 0.0014 0.0047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0115 0.0049 0.0477
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0242 0.0118 0.0137
Loa Loa (eye worm) programmed cell death 8 0.0027 0.0002 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0295 0.0147 0.1596
Schistosoma mansoni caspase-7 (C14 family) 0.0103 0.0043 0.0102
Onchocerca volvulus 0.0042 0.001 0.0089
Brugia malayi glutathione reductase 0.0293 0.0146 0.1411
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0029 0.0002 0.0002
Loa Loa (eye worm) DR-78 0.0054 0.0016 0.0158
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0048 0.016
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0649 0.0339 0.3685
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0016 0.022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0132 0.0058 0.0634
Brugia malayi beta-lactamase family protein 0.0298 0.0149 0.1438
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0048 0.0524
Mycobacterium tuberculosis Conserved protein 0.0298 0.0149 0.1455
Loa Loa (eye worm) hypothetical protein 0.0032 0.0004 0.0039
Plasmodium falciparum pyruvate kinase 0.0105 0.0044 0.2286
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0145 0.0065 0.0217
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0242 0.0118 0.6296
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.0017 0.0055
Loa Loa (eye worm) hypothetical protein 0.0135 0.006 0.0583
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0242 0.0118 0.1282
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Brugia malayi steroid hormone receptor 0.0115 0.0049 0.0477
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0115 0.0049 0.0117
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0102 0.0042 0.0049
Schistosoma mansoni cytochrome P450 0.0037 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.005 0.0014 0.0138
Schistosoma mansoni hypothetical protein 0.0121 0.0053 0.0126
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0029 0.0002 0.0026
Toxoplasma gondii NADPH-glutathione reductase 0.0102 0.0042 0.0621
Loa Loa (eye worm) hypothetical protein 0.0605 0.0315 0.3045
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0002 0.0003
Echinococcus granulosus acetylcholinesterase 0.01 0.0041 0.0048
Echinococcus multilocularis glutamate synthase 0.0027 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.1232 0.0656 0.7121
Chlamydia trachomatis pyruvate kinase 0.0105 0.0044 0.2275
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0005 0.0015
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0027 0.0002 0.0013
Echinococcus multilocularis mothers against decapentaplegic 5 0.009 0.0036 0.0036
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.193 0.1034 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.001 0.0111
Echinococcus multilocularis muscleblind protein 0.0152 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Echinococcus multilocularis beta LACTamase domain containing family member 0.0298 0.0149 0.0149
Onchocerca volvulus 0.0054 0.0016 0.0157
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0114 0.0049 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0221 0.0107 0.0257
Loa Loa (eye worm) hypothetical protein 0.0437 0.0224 0.2167
Trypanosoma cruzi cyclin, putative 0.005 0.0014 0.0047
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0828 0.0436 0.1061
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0011 0.0115
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0005 0.0035
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0242 0.0118 0.0137
Echinococcus multilocularis isocitrate dehydrogenase 0.0114 0.0049 0.0049
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0117 0.005 0.0488
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0037 0.0007 0.017
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0114 0.0049 0.0155
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0042 0.001 0.0032
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0242 0.0118 0.0137
Brugia malayi 6-phosphofructokinase 0.0113 0.0048 0.0469
Echinococcus multilocularis 0.0242 0.0118 0.0118
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.0017 0.0055
Trypanosoma cruzi major cysteine proteinase, putative 0.0069 0.0024 0.008
Echinococcus multilocularis cyclin B 0.005 0.0014 0.0014
Echinococcus granulosus mothers against decapentaplegic 5 0.009 0.0036 0.0042
Echinococcus granulosus lysosomal alpha glucosidase 0.0528 0.0273 0.0317
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0037 0.0007 0.017
Trypanosoma cruzi target of rapamycin kinase 3 0.1233 0.0656 0.2183
Mycobacterium ulcerans carboxylesterase, LipT 0.0308 0.0154 0.3976
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Echinococcus granulosus muscleblind protein 0.0152 0.0069 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0493 0.0254 0.6576
Echinococcus multilocularis musashi 0.011 0.0046 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.026 0.0128 0.1235
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0242 0.0118 0.1788
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0011
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0029 0.0002 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0037 0.0007 0.0064
Echinococcus multilocularis pyruvate kinase 0.0054 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1191 0.0633 0.9507
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1905 0.102 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.002 0.0192
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Echinococcus granulosus expressed protein 0.0033 0.0005 0.0006
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0073 0.0027 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0323 0.0162 0.0539
Onchocerca volvulus 0.0768 0.0403 0.4153
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Echinococcus granulosus synaptojanin 1 0.0029 0.0002 0.0003
Trypanosoma cruzi metacaspase 5, putative 0.0053 0.0016 0.0052
Leishmania major pyruvate kinase 0.0105 0.0044 0.0139
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0017
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0132 0.0058 0.6427
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0011
Schistosoma mansoni nuclear receptor 0.0054 0.0016 0.0037
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0528 0.0273 0.2643
Loa Loa (eye worm) hypothetical protein 0.0298 0.0149 0.1438
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0172
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0649 0.0339 0.3685
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0037 0.0007 0.0064
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0477 0.0246 0.0285
Loa Loa (eye worm) patched family protein 0.0117 0.005 0.0487
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0016 0.0172
Brugia malayi hypothetical protein 0.1459 0.0778 0.7528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0715 0.0375 0.4074
Giardia lamblia Phosphatidylinositol 4-kinase 0.0242 0.0118 0.1754
Leishmania major mitochondrial DNA polymerase beta 0.0323 0.0162 0.0517
Mycobacterium ulcerans aldehyde dehydrogenase 0.043 0.022 0.5691
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0132 0.0058 0.0564
Loa Loa (eye worm) hypothetical protein 0.0115 0.0049 0.0477
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0477 0.0246 0.0246
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0308 0.0154 0.2297
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0145 0.0065 0.0639
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0012 0.0026
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0828 0.0436 0.0436
Brugia malayi Matrixin family protein 0.0605 0.0315 0.3045
Trichomonas vaginalis conserved hypothetical protein 0.0512 0.0265 0.2877
Loa Loa (eye worm) hypothetical protein 0.0043 0.001 0.0099
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0145 0.0065 0.0639
Plasmodium falciparum cysteine proteinase falcipain 3 0.0043 0.001 0.0483
Entamoeba histolytica hypothetical protein 0.0242 0.0118 0.1131
Trichomonas vaginalis PIKK family atypical protein kinase 0.1251 0.0666 0.7231
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0029 0.0002 0.0007
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0061 0.002 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0058 0.0634
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1251 0.0666 0.2217
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.0111 0.1073
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Echinococcus granulosus microtubule associated protein 2 0.7586 0.4103 0.4758
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0493 0.0254 0.6576
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Giardia lamblia G2/mitotic-specific cyclin B 0.005 0.0014 0.0191
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0029 0.0002 0.0007
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0102 0.0042 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Loa Loa (eye worm) hypothetical protein 0.0044 0.0011 0.0102
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0004 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0004 0.0039
Echinococcus granulosus adam 17 protease 0.155 0.0828 0.096
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0002 0.0016
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0295 0.0147 0.0147
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0041 0.0137
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0054 0.0016 0.0157
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0145 0.0065 0.0217
Trypanosoma cruzi hypothetical protein, conserved 0.0132 0.0058 0.0194
Loa Loa (eye worm) phosphatidylinositol 3 0.012 0.0052 0.0501
Onchocerca volvulus Cathepsin L homolog 0.0043 0.001 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.1232 0.0656 0.7121
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0013 0.0173
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0029 0.0002 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0013 0.0136
Trypanosoma brucei unspecified product 0.0051 0.0014 0.0193
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0533 0.0276 0.032
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0041 0.0602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0295 0.0147 0.7855
Schistosoma mansoni ap endonuclease 0.0141 0.0064 0.0152
Echinococcus granulosus thyroid hormone receptor alpha 0.0054 0.0016 0.0019
Brugia malayi polk-prov protein 0.005 0.0014 0.0136
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0102 0.0042 0.0609
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0295 0.0147 0.1596
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.011
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0004 0.0005
Trichomonas vaginalis pyruvate kinase, putative 0.0105 0.0044 0.0474
Onchocerca volvulus 0.0121 0.0053 0.0533
Giardia lamblia DINP protein human, muc B family 0.008 0.003 0.0434
Brugia malayi Matrixin family protein 0.1842 0.0986 0.954
Leishmania major phosphatidylinositol 4-kinase, putative 0.0242 0.0118 0.0376
Schistosoma mansoni rotamase 0.0033 0.0005 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0121 0.0053 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0115 0.0049 0.0477
Brugia malayi ecdysone receptor 0.0054 0.0016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0368 0.0187 0.1804
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0668 0.035 0.3425
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0029 0.0002 0.0023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0117 0.005 0.0548
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0242 0.0118 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0005 0.0053
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0145 0.0065 0.1687
Brugia malayi conserved hypotetical protein 0.0054 0.0016 0.0158
Mycobacterium ulcerans acyl-CoA synthetase 0.0145 0.0065 0.1687
Loa Loa (eye worm) hypothetical protein 0.0068 0.0024 0.0232
Brugia malayi MH2 domain containing protein 0.009 0.0036 0.0348
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0361 0.0183 0.0443
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0011 0.0025
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0029 0.0002 0.0011
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0029 0.0002 0.0013
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.043 0.022 0.0701
Brugia malayi beta-lactamase family protein 0.0298 0.0149 0.1438
Brugia malayi hypothetical protein 0.005 0.0014 0.0134
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0016 0.0037
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0054 0.0016 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0037 0.0007 0.0064
Brugia malayi Cytochrome P450 family protein 0.0116 0.005 0.048
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0004 0.0039
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0293 0.0146 0.1428
Onchocerca volvulus 0.0298 0.0149 0.1523
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0118 0.0051 0.0059
Schistosoma mansoni hypothetical protein 0.0798 0.042 0.1021
Giardia lamblia NADH oxidase lateral transfer candidate 0.0102 0.0042 0.0609
Entamoeba histolytica cysteine proteinase 1, putative 0.0033 0.0005 0.0035
Echinococcus multilocularis aminopeptidase N 0.0042 0.001 0.001
Brugia malayi Patched related family protein 4 0.0117 0.005 0.0487
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0104 0.1128
Trypanosoma brucei unspecified product 0.0094 0.0038 0.0546
Trichomonas vaginalis PIKK family atypical protein kinase 0.1202 0.0639 0.6941
Echinococcus multilocularis deoxyribonuclease 1 2 0.0029 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0037 0.0007 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0098 0.1064
Loa Loa (eye worm) pyruvate kinase 0.0105 0.0044 0.0422
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0013 0.0136
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0029 0.0002 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0156 0.1696
Echinococcus granulosus pyruvate kinase 0.0054 0.0016 0.0019
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0001 0.0007
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0668 0.035 0.8958
Mycobacterium tuberculosis Conserved protein 0.0298 0.0149 0.1455
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0115 0.0049 0.0057
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0054 0.0016 0.0016
Brugia malayi Carboxylesterase family protein 0.0045 0.0011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0754 0.0396 0.4302
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0533 0.0276 0.067
Brugia malayi Cytochrome P450 family protein 0.0055 0.0017 0.0161
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0027 0.0002 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Leishmania major RNA-editing complex protein MP100, putative 0.0029 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.005 0.0014 0.0134
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0048 0.0115
Loa Loa (eye worm) nuclear factor I 0.005 0.0014 0.0136
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0037 0.0007 0.017
Loa Loa (eye worm) hypothetical protein 0.0121 0.0053 0.051
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0288 0.0143 0.3647
Loa Loa (eye worm) pyruvate kinase 0.0105 0.0044 0.0422
Brugia malayi RNA recognition motif domain containing protein 0.0521 0.0269 0.2604
Onchocerca volvulus Cathepsin L homolog 0.0043 0.001 0.0094
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0048 0.0467
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Leishmania major alpha glucosidase II subunit, putative 0.0117 0.005 0.016
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0295 0.0147 0.1596
Brugia malayi glutaminase DH11.1 0.0278 0.0138 0.1331
Echinococcus granulosus Protein patched homolog 1 0.0828 0.0436 0.0506
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.001 0.0111
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Brugia malayi Nuclear hormone receptor-like 1 0.0115 0.0049 0.0477
Loa Loa (eye worm) hypothetical protein 0.0054 0.0016 0.0158
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0242 0.0118 0.1131
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0818 0.0431 0.0499
Loa Loa (eye worm) hypothetical protein 0.0117 0.005 0.0487
Entamoeba histolytica acyl-CoA synthetase, putative 0.0493 0.0254 0.2449
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1251 0.0666 0.6433
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.001 0.001
Echinococcus granulosus serine protein kinase ATM 0.0694 0.0363 0.0421
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0002 0.0016
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0072 0.0026 0.0026
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0054 0.0532
Onchocerca volvulus 0.0921 0.0487 0.5015
Echinococcus multilocularis thyroid hormone receptor alpha 0.0239 0.0116 0.0116
Trypanosoma cruzi cysteine peptidase, putative 0.01 0.0041 0.0136
Trypanosoma cruzi polo-like protein kinase, putative 0.0477 0.0246 0.0817
Brugia malayi hypothetical protein 0.0054 0.0016 0.0158
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0044 0.0011 0.0011
Mycobacterium ulcerans monoxygenase 0.0027 0.0002 0.0034
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0042 0.0139
Onchocerca volvulus 0.0132 0.0058 0.0591
Echinococcus multilocularis pyruvate kinase 0.0105 0.0044 0.0044
Trypanosoma brucei metacaspase 0.0053 0.0016 0.0216
Trypanosoma brucei glucosidase, putative 0.0117 0.005 0.0737
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 1.5919 0.8624 1
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0649 0.0339 0.3685
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0242 0.0118 0.6296
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0145 0.0065 0.3459
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0011 0.0036
Trichomonas vaginalis maltase-glucoamylase, putative 0.0117 0.005 0.0548
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0115 0.0049 0.0477
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0029 0.0002 0.0007
Echinococcus multilocularis dnaJ subfamily B 0.2577 0.1385 0.1385
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.001 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0016 0.0019
Trypanosoma cruzi PAB1-binding protein , putative 0.0161 0.0074 0.0246
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0141 0.0064 0.0074
Echinococcus multilocularis smad 0.009 0.0036 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0493 0.0254 0.2489
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0002 0.0002
Schistosoma mansoni smad1 5 8 and 0.009 0.0036 0.0085
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0548 0.0284 0.3085
Giardia lamblia Pyruvate kinase 0.0054 0.0016 0.0218
Echinococcus multilocularis cysteine protease 0.0043 0.001 0.001
Echinococcus multilocularis dna polymerase eta 0.0098 0.004 0.004
Onchocerca volvulus 0.011 0.0046 0.0468
Leishmania major cytochrome p450-like protein 0.0055 0.0017 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0115 0.0049 0.0477
Leishmania major DNA polymerase eta, putative 0.0098 0.004 0.0127
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0278 0.0138 0.0333
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0678 0.0355 0.0412
Schistosoma mansoni jumonji/arid domain-containing protein 0.0132 0.0058 0.014
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0114 0.0049 0.0162
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0145 0.0065 0.1643
Onchocerca volvulus Protein patched homolog 0.0117 0.005 0.0509
Trichomonas vaginalis cyclins, putative 0.0034 0.0006 0.0061
Brugia malayi Patched related family protein 10 0.0117 0.005 0.0487
Leishmania major hypothetical protein, conserved 0.0029 0.0002 0.0007
Brugia malayi Cathepsin L-like precursor 0.0043 0.001 0.0099
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0048 0.0704
Mycobacterium ulcerans dehydrogenase 0.0027 0.0002 0.0034
Trypanosoma cruzi metacaspase, putative 0.0053 0.0016 0.0052
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0726 0.0381 0.0381
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0295 0.0147 0.017
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0361 0.0183 0.1987
Mycobacterium leprae conserved hypothetical protein 0.0242 0.0118 0.2999
Mycobacterium ulcerans pyruvate kinase 0.0105 0.0044 0.1124
Brugia malayi Patched family protein 0.0117 0.005 0.0487
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0011 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0242 0.0118 0.1282
Brugia malayi hypothetical protein 0.0121 0.0053 0.051
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.019 0.009 1
Trichomonas vaginalis glutathione reductase, putative 0.0102 0.0042 0.0456
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0011 0.0095
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0115 0.0049 0.0049
Brugia malayi Doublecortin family protein 0.0121 0.0053 0.051
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0033 0.0005 0.0009
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0016 0.0786
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0003 0.0038
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0002 0.0016
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0002 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.001 0.0099
Brugia malayi nuclear receptor RXR 0.0054 0.0016 0.0158
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0463 0.0238 0.2304
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0048 0.0524
Loa Loa (eye worm) hypothetical protein 0.0605 0.0315 0.3045
Loa Loa (eye worm) hypothetical protein 0.0057 0.0018 0.0174
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0017 0.0161
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0025 0.0082
Trichomonas vaginalis penicillin-binding protein, putative 0.0298 0.0149 0.1615
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1243 0.0661 0.0661
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Brugia malayi Cathepsin L-like precursor 0.0043 0.001 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.01 0.0041 0.0595
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0007 0.0015
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0117 0.005 0.0751
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.001 0.0022
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0048 0.1244
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0027 0.0002 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0115 0.0049 0.0477
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0295 0.0147 0.017
Brugia malayi F/Y-rich N-terminus family protein 0.0074 0.0027 0.0259
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0102 0.0042 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.0307 0.3334
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0493 0.0254 0.6576

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 200 ug ml-1 Inhibition of HIV1 RT ChEMBL. 1710653
Inhibition (binding) = 7 % Compound was tested for its inhibitory effect on MAO-B ( Monoamine Oxidase) at 100 uM ChEMBL. 11123983
Inhibition (binding) = 9 % Compound was tested for its inhibitory effect on MAO-A ( Monoamine Oxidase) at 100 uM ChEMBL. 11123983
Inhibition (binding) = 29.6 % Percentage inhibition was obtained by performing in vitro assay on purified recombinant integrase by 3''-processing method at 100 micro g/mL (experiment 2) ChEMBL. 9083481
Inhibition (binding) < 30 % Inhibition of COX2 at 100 uM by scintillation proximity assay ChEMBL. 12444669
Inhibition (binding) = 34.2 % Percentage inhibition was obtained by performing in vitro assay on purified recombinant integrase by strand transfer method at 100 micro g/mL (experiment 2) ChEMBL. 9083481
Inhibition (binding) = 40.8 % Percentage inhibition was obtained by performing in vitro assay on purified recombinant integrase by 3''-processing method at 100 micro g/mL (experiment 1) ChEMBL. 9083481
Inhibition (binding) = 67.7 % Percentage inhibition was obtained by performing in vitro assay on purified recombinant integrase by strand transfer method at 100 micro g/mL (experiment 1) ChEMBL. 9083481
Potency (functional) = 0.7079 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1476 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent))] ChEMBL. No reference
Potency (functional) 8.1098 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.0993 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 43.3517 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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