Detailed information for compound 225204

Basic information

Technical information
  • TDR Targets ID: 225204
  • Name: methyl 3-(4-ethenylphenyl)-8-azabicyclo[3.2.1 ]octane-2-carboxylate
  • MW: 271.354 | Formula: C17H21NO2
  • H donors: 1 H acceptors: 1 LogP: 2.93 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1C2CCC(N2)CC1c1ccc(cc1)C=C
  • InChi: 1S/C17H21NO2/c1-3-11-4-6-12(7-5-11)14-10-13-8-9-15(18-13)16(14)17(19)20-2/h3-7,13-16,18H,1,8-10H2,2H3
  • InChiKey: KHYFCJWXLVZFLY-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • methyl 3-(4-vinylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
  • 3-(4-vinylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Dopamine transporter Starlite/ChEMBL References
Rattus norvegicus Norepinephrine transporter Starlite/ChEMBL References
Rattus norvegicus Serotonin transporter Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis sodium and chloride dependent glycine Norepinephrine transporter   597 aa 507 aa 38.9 %
Onchocerca volvulus Transmembrane protein 120 homolog Norepinephrine transporter   597 aa 577 aa 34.0 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 595 aa 34.0 %
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative Norepinephrine transporter   597 aa 579 aa 22.1 %
Schistosoma mansoni sodium/chloride dependent transporter Norepinephrine transporter   597 aa 534 aa 41.0 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Norepinephrine transporter   597 aa 501 aa 39.7 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Norepinephrine transporter   597 aa 569 aa 24.8 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 522 aa 22.0 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 579 aa 35.1 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Norepinephrine transporter   597 aa 545 aa 41.7 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Norepinephrine transporter   597 aa 551 aa 47.4 %
Echinococcus multilocularis sodium and chloride dependent glycine Norepinephrine transporter   597 aa 529 aa 42.0 %
Schistosoma mansoni sodium/chloride dependent transporter Norepinephrine transporter   597 aa 529 aa 41.6 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 508 aa 32.7 %
Plasmodium knowlesi transporter, putative Serotonin transporter   630 aa 514 aa 20.2 %
Plasmodium vivax hypothetical protein, conserved Serotonin transporter   630 aa 528 aa 21.2 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Norepinephrine transporter   597 aa 513 aa 38.4 %
Echinococcus granulosus sodium and chloride dependent glycine Norepinephrine transporter   597 aa 529 aa 42.5 %
Neospora caninum sodium-dependent transporter, putative Norepinephrine transporter   597 aa 507 aa 30.4 %
Loa Loa (eye worm) hypothetical protein Norepinephrine transporter   597 aa 551 aa 25.0 %
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Norepinephrine transporter   597 aa 549 aa 41.9 %
Echinococcus granulosus sodium and chloride dependent glycine Norepinephrine transporter   597 aa 507 aa 38.9 %
Brugia malayi Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 581 aa 34.6 %
Plasmodium yoelii hypothetical protein Norepinephrine transporter   597 aa 478 aa 19.7 %
Onchocerca volvulus Norepinephrine transporter   597 aa 540 aa 46.3 %
Onchocerca volvulus Norepinephrine transporter   597 aa 548 aa 24.8 %
Onchocerca volvulus Norepinephrine transporter   597 aa 554 aa 38.6 %
Plasmodium vivax amine transporter, putative Norepinephrine transporter   597 aa 483 aa 21.1 %
Onchocerca volvulus Norepinephrine transporter   597 aa 570 aa 38.6 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.002 0.0001 0.0002
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0028 0.0046
Trypanosoma brucei unspecified product 0.0067 0.0091 0.0153
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0003 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.003 0.0021 0.002
Plasmodium falciparum JmjC domain-containing protein, putative 0.0145 0.0239 0.0406
Treponema pallidum exodeoxyribonuclease (exoA) 0.0098 0.0149 0.1392
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.003 0.0021 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Echinococcus multilocularis pyruvate kinase 0.0034 0.0028 0.0028
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0403 0.0726 0.0725
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 0.6797
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0031 0.0022 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.004 0.004
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0002
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0169 0.0284 0.0482
Echinococcus granulosus beta LACTamase domain containing family member 0.0218 0.0377 0.0377
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0036 0.0032 0.0173
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0147 0.0796
Echinococcus multilocularis caspase 2 0.0084 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.1525 0.2849 0.2849
Echinococcus multilocularis fibrillin 1 0.0027 0.0014 0.0014
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0024 0.0009 0.0009
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.003 0.0021 0.0284
Echinococcus granulosus importin subunit beta 1 0.0028 0.0018 0.0018
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0099 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Onchocerca volvulus 0.0702 0.1292 0.6993
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0027 0.0015 0.0025
Schistosoma mansoni immunophilin 0.0169 0.0284 0.0284
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.017 0.0285 0.2826
Schistosoma mansoni sodium/chloride dependent transporter 0.01 0.0153 0.0153
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0047 0.0047
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus granulosus p2X purinoceptor 4 0.0286 0.0504 0.0504
Brugia malayi Protein kinase domain containing protein 0.0082 0.012 0.012
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0197 0.0336 0.0571
Echinococcus granulosus p2X purinoceptor 4 0.0286 0.0504 0.0504
Echinococcus multilocularis dnaJ subfamily B 0.1268 0.2363 0.2363
Echinococcus granulosus retinol dehydrogenase 11 0.003 0.0021 0.0021
Schistosoma mansoni opsin-like receptor 0.0702 0.1292 0.1292
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0083 0.0121 0.0206
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0054 0.009
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0155 0.0155
Echinococcus multilocularis p2X purinoceptor 4 0.0286 0.0504 0.0504
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0027 0.0015 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0218 0.0377 0.0642
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0702 0.1292 0.1292
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0441 0.0799 0.0799
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0405 0.0405
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.003 0.0021 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Mycobacterium leprae conserved hypothetical protein 0.0218 0.0377 0.0375
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.003 0.0021 0.002
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0015 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0702 0.1292 0.1292
Mycobacterium ulcerans ketoacyl reductase 0.003 0.0021 0.0019
Onchocerca volvulus 0.003 0.0021 0.0113
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Loa Loa (eye worm) FolC protein 0.0197 0.0336 0.0336
Echinococcus granulosus allatostatin A receptor 0.0702 0.1292 0.1292
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0015 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0114 0.1132
Brugia malayi G-protein coupled receptor 0.0702 0.1292 0.1292
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.003 0.0021 0.0019
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Mycobacterium ulcerans DNA polymerase IV 0.0074 0.0103 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0021 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Onchocerca volvulus 0.0027 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0018 0.003
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0021 0.0019
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.003 0.0021 0.0035
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0031 0.0022 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0145 0.0239 0.0239
Schistosoma mansoni glutamate synthase 0.0027 0.0015 0.0015
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0021 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0098 0.0149 0.0252
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0029 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0035 0.0035
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0654 0.12 0.1199
Echinococcus granulosus thioredoxin glutathione reductase 0.0291 0.0515 0.0515
Echinococcus multilocularis deoxyribonuclease 1 2 0.002 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0047 0.0461
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0197 0.0336 0.0336
Loa Loa (eye worm) neuropeptide F receptor 0.0702 0.1292 0.1292
Trypanosoma brucei metacaspase 0.0044 0.0047 0.0077
Plasmodium falciparum transporter, putative 0.0099 0.0152 0.0257
Loa Loa (eye worm) hypothetical protein 0.0374 0.0672 0.0672
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.003 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0073 0.0101 0.0101
Brugia malayi cytochrome P450 0.003 0.0021 0.0021
Onchocerca volvulus 0.0119 0.019 0.1027
Brugia malayi Dehydrogenases, short chain protein 30 0.003 0.0021 0.0021
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0009 0.0009
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Mycobacterium tuberculosis Possible ketoacyl reductase 0.003 0.0021 0.0019
Brugia malayi small heat shock protein 0.0569 0.1041 0.1041
Brugia malayi neuropeptide F receptor 0.0702 0.1292 0.1292
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0015 0.0015
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0242 0.0422 0.0422
Giardia lamblia Hypothetical protein 0.005 0.0058 0.0772
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0374 0.0672 0.1146
Brugia malayi beta-lactamase family protein 0.0218 0.0377 0.0377
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0249 0.0436 0.0741
Brugia malayi Tachykinin-like peptides receptor 99D 0.0702 0.1292 0.1292
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0001 0.0001
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0047 0.0079
Trypanosoma cruzi cysteine peptidase, putative 0.0091 0.0135 0.0231
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0028 0.0046
Onchocerca volvulus 0.0027 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Onchocerca volvulus 0.0437 0.079 0.4275
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0066 0.0658
Echinococcus multilocularis neuropeptide receptor 0.0702 0.1292 0.1292
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0015 0.0202
Brugia malayi MAP kinase sur-1 0.0054 0.0066 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0066 0.0658
Echinococcus granulosus regulator of G protein signaling 7 0.0025 0.0012 0.0012
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0015 0.0147
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0023 0.0008 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0234 0.0234
Onchocerca volvulus 0.0024 0.0009 0.0049
Echinococcus granulosus hypothetical protein 0.0702 0.1292 0.1292
Toxoplasma gondii GAF domain-containing protein 0.0079 0.0114 0.0195
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.004 0.004
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0042 0.0068
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0066 0.0066
Onchocerca volvulus 0.0023 0.0007 0.0037
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0249 0.0436 0.4314
Leishmania major dehydrogenase-like protein 0.003 0.0021 0.0035
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0036 0.0033 0.0033
Plasmodium falciparum glutathione reductase 0.0101 0.0155 0.0263
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0015 0.0023
Plasmodium falciparum cysteine proteinase falcipain 3 0.0024 0.0009 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0441 0.0799 0.0799
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0015 0.0025
Leishmania major hypothetical protein, conserved 0.0027 0.0015 0.0024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0076 0.0108 0.0108
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0038 0.0035 0.0059
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0023 0.0008 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0076 0.0108 0.0108
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0076 0.0108 0.0108
Echinococcus granulosus thymidylate synthase 0.0996 0.1847 0.1847
Echinococcus granulosus biogenic amine 5HT receptor 0.0702 0.1292 0.1292
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0098 0.0149 0.0253
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0032 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Onchocerca volvulus 0.0051 0.006 0.0324
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Trypanosoma cruzi metacaspase, putative 0.0044 0.0047 0.0079
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0169 0.0284 0.2658
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0147 0.0251
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.3119 0.5861 1
Mycobacterium leprae Probable lipase LipE 0.0218 0.0377 0.0375
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0169 0.0284 0.2814
Leishmania major DNA polymerase eta, putative 0.0073 0.0101 0.0172
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0099 0.0152 0.0152
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1395 0.2602 0.2601
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0036 0.0032 0.0032
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0101 0.0155 0.0264
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0251 0.044 0.044
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0027 0.0015 0.0015
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0023 0.0008 0.0008
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0169 0.0284 0.0284
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0219
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0258
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0035 0.006
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0145 0.0239 0.0407
Echinococcus granulosus traf and tnf receptor associated protein 0.002 0.0001 0.0001
Trypanosoma cruzi mitochondrial protein 99, putative 0.002 0.0001 0.0002
Echinococcus multilocularis sex peptide receptor 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0089 0.0132 0.0715
Trypanosoma brucei trypanothione reductase 0.0291 0.0515 0.0876
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0038 0.0035 0.0035
Schistosoma mansoni neuropeptide F-like receptor 0.0702 0.1292 0.1292
Treponema pallidum thioredoxin reductase (trxB) 0.0027 0.0015 0.0137
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0022 0.0037
Echinococcus granulosus dihydrofolate reductase 0.5307 1 1
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0021 0.0003 0.0004
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0038 0.0063
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0031 0.0023 0.0039
Plasmodium falciparum phosphodiesterase gamma, putative 0.0031 0.0022 0.0036
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0002
Mycobacterium ulcerans DNA polymerase IV 0.0074 0.0103 0.0102
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0197 0.0336 0.0336
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0027 0.0015 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0209 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0076 0.0108 0.0108
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0038 0.0065
Trichomonas vaginalis DNA helicase recq1, putative 0.0091 0.0135 0.134
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0023 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.005 0.0058 0.0791
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.002 0.0001 0.0014
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Brugia malayi hypothetical protein 0.0126 0.0202 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0022 0.0219
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0023 0.0008 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0054 0.0092
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0209 0.0355
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0098 0.0149 0.0252
Brugia malayi hypothetical protein 0.012 0.0191 0.0191
Giardia lamblia Glutamate synthase 0.0027 0.0015 0.0182
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.0008 0.0092
Onchocerca volvulus Bile acid receptor homolog 0.0076 0.0108 0.0584
Echinococcus granulosus 7tm_1 domain containing protein 0.0702 0.1292 0.1292
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0147 0.0147
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Brugia malayi Cell death protein 3 precursor 0.0084 0.0123 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Onchocerca volvulus 0.003 0.0021 0.0113
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0101 0.0173
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0147 0.0147
Onchocerca volvulus 0.0035 0.003 0.0164
Schistosoma mansoni tar DNA-binding protein 0.0188 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium ulcerans thymidylate synthase 0.0996 0.1847 0.1846
Echinococcus multilocularis fmrfamide receptor 0.0702 0.1292 0.1292
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Onchocerca volvulus 0.0702 0.1292 0.6993
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0378 0.374
Loa Loa (eye worm) retinol dehydrogenase 12 0.0021 0.0003 0.0003
Schistosoma mansoni rab6-interacting 0.0019 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0021 0.0035
Echinococcus multilocularis neuropeptide FF receptor 2 0.0702 0.1292 0.1292
Echinococcus granulosus biogenic amine 5HT receptor 0.0702 0.1292 0.1292
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0434 0.0434
Brugia malayi ORL1-like opioid receptor 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0191 0.0326 0.0326
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0434 0.0434
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0027 0.0015 0.0147
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0037 0.0035 0.0035
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0031 0.0022 0.0022
Mycobacterium ulcerans oxidoreductase 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Onchocerca volvulus 0.0052 0.0062 0.0335
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0209 0.0209
Entamoeba histolytica hypothetical protein, conserved 0.003 0.0021 0.0284
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0101 0.0155 0.0263
Trypanosoma cruzi cysteine peptidase, putative 0.0091 0.0135 0.0231
Schistosoma mansoni transcription factor LCR-F1 0.0261 0.0457 0.0457
Echinococcus granulosus intermediate filament protein 0.0054 0.0066 0.0066
Brugia malayi hypothetical protein 0.012 0.0191 0.0191
Echinococcus multilocularis fmrfamide receptor 0.0702 0.1292 0.1292
Echinococcus granulosus lamin dm0 0.0054 0.0066 0.0066
Trypanosoma cruzi PAB1-binding protein , putative 0.0126 0.0202 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0001 0.0001
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0209 0.2843
Brugia malayi hypothetical protein 0.004 0.004 0.004
Mycobacterium leprae Probable oxidoreductase 0.003 0.0021 0.0019
Echinococcus multilocularis retinol dehydrogenase 11 0.003 0.0021 0.0021
Loa Loa (eye worm) TAR-binding protein 0.0188 0.032 0.032
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0031 0.0023 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0015 0.0147
Onchocerca volvulus 0.0111 0.0175 0.0946
Echinococcus multilocularis conserved hypothetical protein 0.003 0.0021 0.0021
Trypanosoma cruzi short-chain dehydrogenase, putative 0.003 0.0021 0.0035
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0021 0.0003 0.0001
Toxoplasma gondii ABC1 family protein 0.0218 0.0377 0.0643
Leishmania major short chain dehydrogenase-like protein 0.003 0.0021 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0378 0.374
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0169 0.0284 0.0284
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0047 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0022 0.0037
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0022 0.0035
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0076 0.0108 0.0108
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.0197 0.0336 0.0335
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0076 0.0108 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0076 0.0107 0.0107
Mycobacterium leprae putative cytochrome p450 0.003 0.0021 0.0019
Mycobacterium ulcerans glutamate synthase subunit beta 0.0027 0.0015 0.0013
Onchocerca volvulus Folate transporter 1 homolog 0.005 0.0058 0.0314
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Loa Loa (eye worm) fibroinase 0.0024 0.0009 0.0009
Echinococcus multilocularis laminin 0.0027 0.0014 0.0014
Toxoplasma gondii endonuclease IV APN 0.0076 0.0107 0.0182
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0037 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0028 0.0048
Schistosoma mansoni neuropeptide receptor 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0204 0.0203
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0106 0.0106
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.003 0.0021 0.0033
Echinococcus multilocularis glycoprotein Antigen 5 0.0023 0.0007 0.0007
Trichomonas vaginalis fk506-binding protein, putative 0.0023 0.0008 0.0081
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0038 0.0377
Echinococcus multilocularis g-protein coupled receptor 0.0702 0.1292 0.1292
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0249 0.0436 0.0741
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Leishmania major 3-keto-dihydrosphingosine reductase 0.003 0.0021 0.0035
Trichomonas vaginalis helicase, putative 0.0027 0.0015 0.0151
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0702 0.1292 0.6993
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.0204 0.0203
Loa Loa (eye worm) jmjC domain-containing protein 0.0145 0.0239 0.0239
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0098 0.0149 0.2027
Trypanosoma cruzi Vacuolar proton pyrophosphatase 1, putative 0.0331 0.0589 0.1005
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0403 0.0726 0.0726
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.003 0.0021 0.0019
Brugia malayi Serotonin receptor 0.0702 0.1292 0.1292
Echinococcus granulosus sodium and chloride dependent glycine 0.0099 0.0152 0.0152
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.003 0.0021 0.0019
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0021 0.0003 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0702 0.1292 0.1292
Schistosoma mansoni lipoxygenase 0.0054 0.0067 0.0067
Brugia malayi glutaminase DH11.1 0.0537 0.098 0.098
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0076 0.0108 0.0108
Onchocerca volvulus Cell death protein 3 homolog 0.0084 0.0123 0.0668
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0664 0.122 0.1219
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Leishmania major short chain dehydrogenase, putative 0.003 0.0021 0.0035
Mycobacterium ulcerans short-chain dehydrogenase 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0021 0.0003 0.0004
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0027 0.0015 0.0202
Onchocerca volvulus 0.003 0.0021 0.0113
Echinococcus granulosus hypothetical protein 0.003 0.0021 0.0021
Mycobacterium ulcerans ferredoxin reductase 0.0027 0.0015 0.0013
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0101 0.0155 0.0263
Mycobacterium ulcerans beta-lactamase 0.0218 0.0377 0.0375
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0036 0.0032 0.0032
Echinococcus granulosus caspase 2 0.0084 0.0123 0.0123
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0023 0.0008 0.0006
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0007
Brugia malayi dehydrogenases, short chain protein 2 0.003 0.0021 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Leishmania major folylpolyglutamate synthetase 0.0197 0.0336 0.0572
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0702 0.1292 0.1292
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0038 0.0035 0.006
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0021 0.0035
Leishmania major pantothenate kinase subunit, putative 0.002 0.0003 0.0004
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0009 0.0009
Trichomonas vaginalis fk506-binding protein, putative 0.0169 0.0284 0.2814
Schistosoma mansoni amine GPCR 0.0702 0.1292 0.1292
Loa Loa (eye worm) runx1 0.0055 0.0068 0.0068
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Echinococcus multilocularis GPCR, family 2 0.0112 0.0177 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Echinococcus granulosus RUN 0.0019 0.0001 0.0001
Schistosoma mansoni lipoxygenase 0.0019 0.0001 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0702 0.1292 0.1292
Mycobacterium ulcerans hypothetical protein 0.0117 0.0185 0.0183
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0027 0.0015 0.0013
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0031 0.0022 0.0022
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Onchocerca volvulus 0.0099 0.0151 0.082
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Onchocerca volvulus 0.003 0.0021 0.0113
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0197 0.0336 0.0573
Leishmania major DNA polymerase eta, putative 0.004 0.0039 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Echinococcus multilocularis dro:myosuppressin receptor 0.0702 0.1292 0.1292
Echinococcus granulosus caspase 3 0.0072 0.01 0.01
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0031 0.0022 0.0022
Echinococcus multilocularis dna polymerase eta 0.0073 0.0101 0.0101
Toxoplasma gondii exonuclease III APE 0.0098 0.0149 0.0254
Onchocerca volvulus 0.0702 0.1292 0.6993
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0079 0.0114 0.0113
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0021 0.0003 0.0002
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0028 0.0153
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0056 0.0096
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0101 0.0155 0.0264
Leishmania major hypothetical protein, conserved 0.003 0.0021 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.003 0.0021 0.002
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0147 0.0147
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 0.0725
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0035 0.0059
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0031 0.0022 0.0022
Trypanosoma brucei short-chain dehydrogenase, putative 0.003 0.0021 0.0033
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0035 0.0059
Echinococcus multilocularis Protein lozenge 0.0055 0.0068 0.0068
Echinococcus multilocularis sodium and chloride dependent glycine 0.0099 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0101 0.0155 0.0264
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0027 0.0015 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0441 0.0799 0.0799
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0209 0.0209
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Onchocerca volvulus 0.047 0.0853 0.4615
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0023 0.0008 0.0014
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0021 0.0003 0.0005
Trypanosoma cruzi metacaspase, putative 0.0044 0.0047 0.0079
Trypanosoma brucei PAB1-binding protein , putative 0.0126 0.0202 0.0342
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0076 0.0108 0.0108
Echinococcus granulosus neuropeptide receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0015 0.0151
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Plasmodium vivax vivapain-2 0.0024 0.0009 0.0014
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0197 0.0336 0.0572
Echinococcus multilocularis beta LACTamase domain containing family member 0.0218 0.0377 0.0377
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0037 0.0035 0.0035
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0021 0.0003 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.0702 0.1292 0.1292
Giardia lamblia Hypothetical protein 0.003 0.0021 0.0265
Mycobacterium ulcerans NADH dehydrogenase 0.0027 0.0015 0.0013
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0031 0.0022 0.0022
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Leishmania major pyruvate kinase 0.0034 0.0028 0.0047
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0003 0.0001
Schistosoma mansoni immunophilin 0.0146 0.024 0.024
Leishmania major hypothetical protein, conserved 0.002 0.0001 0.0002
Mycobacterium ulcerans carveol-like dehydrogenase 0.003 0.0021 0.0019
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0066 0.0066
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0035 0.035
Echinococcus granulosus Nuclear hormone receptor HR96 0.0036 0.0032 0.0032
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0031 0.0022 0.0036
Schistosoma mansoni nuclear receptor 0.0036 0.0032 0.0032
Echinococcus multilocularis sodium and chloride dependent glycine 0.0099 0.0152 0.0152
Schistosoma mansoni jumonji/arid domain-containing protein 0.0552 0.1008 0.1008
Mycobacterium ulcerans hypothetical protein 0.0023 0.0007 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0021 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0032 0.0032
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.003 0.0021 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0441 0.0799 0.0799
Schistosoma mansoni glutamate synthase 0.0027 0.0015 0.0015
Onchocerca volvulus 0.0849 0.1569 0.8496
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0031 0.0022 0.0022
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0702 0.1292 0.1292
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0076 0.0108 0.0108
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.004 0.004 0.004
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Mycobacterium ulcerans short-chain dehydrogenase 0.003 0.0021 0.0019
Onchocerca volvulus 0.0702 0.1292 0.6993
Brugia malayi Dopamine receptor protein 2 0.0702 0.1292 0.1292
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0036 0.0032 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0702 0.1292 0.1292
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0038 0.0483
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Onchocerca volvulus 0.0218 0.0377 0.2041
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.002 0.0001 0.0001
Echinococcus multilocularis caspase 0.0115 0.0182 0.0182
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0115 0.0182 0.0182
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0738 0.1361 0.1359
Echinococcus multilocularis neuropeptides capa receptor 0.0702 0.1292 0.1292
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0023 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Schistosoma mansoni nuclear receptor 0.0036 0.0032 0.0032
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0031 0.0022 0.0022
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0038 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0041 0.0041 0.0041
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0413 0.0745 0.0745
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0047 0.0079
Schistosoma mansoni carbonyl reductase 0.003 0.0021 0.0021
Loa Loa (eye worm) ctsf protein 0.0024 0.0009 0.0009
Mycobacterium tuberculosis Probable lipase LipE 0.0218 0.0377 0.0376
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0218 0.0377 0.0376
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0076 0.0108 0.0108
Schistosoma mansoni inositol monophosphatase 0.0039 0.0038 0.0038
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Loa Loa (eye worm) DR-78 0.0036 0.0032 0.0032
Brugia malayi Retinol dehydrogenase 12 0.003 0.0021 0.0021
Echinococcus granulosus lysine specific demethylase 5A 0.0552 0.1008 0.1008
Onchocerca volvulus 0.0041 0.0041 0.0222
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0101 0.0155 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.002 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Echinococcus multilocularis lamin dm0 0.0054 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Mycobacterium ulcerans dehydrogenase/reductase 0.003 0.0021 0.0019
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0145 0.0239 0.0407
Echinococcus multilocularis caspase 8 0.0044 0.0047 0.0047
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Onchocerca volvulus Sepiapterin reductase homolog 0.003 0.0021 0.0113
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.003 0.0021 0.0019
Schistosoma mansoni hypothetical protein 0.1268 0.2363 0.2363
Echinococcus multilocularis ecdysone induced protein 78C 0.0076 0.0108 0.0108
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.002 0.0001 0.0001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0702 0.1292 0.1292
Leishmania major cysteine peptidase A (CPA) 0.0024 0.0009 0.0015
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0038 0.0035 0.0035
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0002 0.0002
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0251 0.044 0.044
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0218 0.0377 0.0377
Brugia malayi nuclear receptor NHR-88 0.0036 0.0032 0.0032
Toxoplasma gondii oxidoreductase, putative 0.003 0.0021 0.0035
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0056 0.0071 0.0071
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0027 0.0015 0.0013
Echinococcus granulosus nuclear receptor nhr 48 0.0036 0.0032 0.0032
Toxoplasma gondii hypothetical protein 0.0219 0.0378 0.0644
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0054 0.0091
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0001 0.0001
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0003 0.0001
Schistosoma mansoni protein phosphatase 2C 0.0145 0.0239 0.0239
Leishmania major short chain dehydrogenase, putative 0.003 0.0021 0.0035
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0031 0.0022 0.0035
Echinococcus granulosus FTZ F1 alpha 0.0076 0.0108 0.0108
Mycobacterium ulcerans monoxygenase 0.0027 0.0015 0.0013
Brugia malayi jmjC domain containing protein 0.0145 0.0239 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Echinococcus granulosus carbonyl reductase 1 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.003 0.0021 0.0019
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.003 0.0021 0.0035
Loa Loa (eye worm) glutathione reductase 0.0291 0.0515 0.0515
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0403 0.0726 0.1239
Loa Loa (eye worm) hypothetical protein 0.0272 0.0479 0.0479
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.002 0.0001 0.0002
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0015 0.0013
Schistosoma mansoni hypothetical protein 0.0702 0.1292 0.1292
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0197 0.0336 0.0336
Mycobacterium ulcerans endonuclease IV 0.0076 0.0107 0.0105
Loa Loa (eye worm) melatonin receptor type 1A 0.0702 0.1292 0.1292
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0403 0.0726 0.1238
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.0204 0.0204
Onchocerca volvulus 0.0702 0.1292 0.6993
Onchocerca volvulus 0.0702 0.1292 0.6993
Plasmodium falciparum metacaspase 1 0.0044 0.0047 0.0078
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0035 0.0059
Schistosoma mansoni biogenic amine receptor 0.0702 0.1292 0.1292
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.003 0.0021 0.0245
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0023 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Entamoeba histolytica disulphide oxidoreductase, putative 0.0027 0.0015 0.0202
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0099 0.0152 0.0152
Leishmania major short chain dehydrogenase/reductase, putative 0.003 0.0021 0.0035
Giardia lamblia DINP protein human, muc B family 0.0054 0.0066 0.0883
Leishmania major cytochrome p450-like protein 0.0049 0.0056 0.0095
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) steroid hormone receptor 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Trichomonas vaginalis mercuric reductase, putative 0.0101 0.0155 0.1535
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0169 0.0284 0.0482
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0251 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0023 0.0007 0.0007
Treponema pallidum hypothetical protein 0.002 0.0001 0.0012
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.003 0.0021 0.0019
Trypanosoma cruzi trypanothione reductase, putative 0.0101 0.0155 0.0264
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0027 0.0015 0.0162
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0545 0.0995 0.0995
Leishmania major basic transcription factor 3a, putative 0.0034 0.0029 0.0049
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0115 0.0182 0.0182
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Trypanosoma brucei DNA polymerase IV, putative 0.0074 0.0103 0.0174
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0702 0.1292 0.6993
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0021 0.0003 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Schistosoma mansoni amine GPCR 0.0702 0.1292 0.1292
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Echinococcus granulosus pyruvate kinase 0.0034 0.0028 0.0028
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Trypanosoma brucei NADH dehydrogenase 0.0027 0.0015 0.0023
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0031 0.0022 0.0037
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.011 0.0172 0.1706
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0027 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.003 0.0021 0.002
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0169 0.0284 0.0284
Echinococcus multilocularis expressed protein 0.0368 0.066 0.066
Schistosoma mansoni survival motor neuron protein 0.0048 0.0054 0.0054
Trypanosoma cruzi short chain dehydrogenase, putative 0.003 0.0021 0.0035
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0021 0.0003 0.0003
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Brugia malayi hypothetical protein 0.0027 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Plasmodium vivax importin-beta 2, putative 0.0028 0.0018 0.0029
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.0204 0.0204
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0702 0.1292 0.1292
Brugia malayi Melatonin receptor type 1A 0.0702 0.1292 0.1292
Mycobacterium ulcerans ketoacyl reductase 0.003 0.0021 0.0019
Trypanosoma cruzi mitochondrial protein 99, putative 0.002 0.0001 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0054 0.0092
Brugia malayi G protein-coupled receptor F59B2.13 0.0702 0.1292 0.1292
Mycobacterium ulcerans lipase LipD 0.0218 0.0377 0.0375
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0023 0.0008 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.0702 0.1292 0.1292
Echinococcus granulosus jumonji domain containing 1A 0.0145 0.0239 0.0239
Echinococcus multilocularis thyroid hormone receptor alpha 0.0076 0.0108 0.0108
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.002 0.0001 0.0001
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.003 0.0021 0.0284
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 0.0723
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0054 0.0066 0.0065
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0021 0.0003 0.0004
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0029 0.0048
Brugia malayi Cytochrome P450 family protein 0.0049 0.0056 0.0056
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2573 0.483 0.483
Schistosoma mansoni biogenic amine (5HT) receptor 0.0702 0.1292 0.1292
Echinococcus granulosus thyroid hormone receptor alpha 0.0036 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Brugia malayi exodeoxyribonuclease III family protein 0.0098 0.0149 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Echinococcus multilocularis snurportin 1 0.0303 0.0538 0.0538
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 0.1238
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0255 0.0447 0.0447
Schistosoma mansoni polycystin 1-related 0.0019 0.0001 0.0001
Trypanosoma cruzi cytochrome p450-like protein, putative 0.003 0.0021 0.0036
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.003 0.0021 0.0021
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0028 0.0047
Brugia malayi hypothetical protein 0.0027 0.0016 0.0016
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0047 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Leishmania major peptidylprolyl isomerase-like protein 0.0169 0.0284 0.0484
Entamoeba histolytica hypothetical protein, conserved 0.003 0.0021 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0031 0.0022 0.0022
Brugia malayi FolC bifunctional protein 0.0197 0.0336 0.0336
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.5307 1 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0101 0.0155 0.0262
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0016 0.0087
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0031 0.0022 0.0022
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0035
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0145 0.0239 0.0239
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0054 0.0052
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0038 0.0064
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Onchocerca volvulus 0.003 0.0021 0.0113
Loa Loa (eye worm) hypothetical protein 0.0437 0.079 0.079
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0251 0.044 0.0749
Trypanosoma cruzi short chain dehydrogenase, putative 0.003 0.0021 0.0035
Schistosoma mansoni hypothetical protein 0.0112 0.0177 0.0177
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0076 0.0108 0.0108
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0099 0.0152 0.0149
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0031 0.0022 0.0037
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0249 0.0436 0.0743
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.003 0.0021 0.0019
Entamoeba histolytica hypothetical protein 0.0261 0.0457 0.6228
Onchocerca volvulus 0.0702 0.1292 0.6993
Giardia lamblia hypothetical protein 0.0031 0.0022 0.0282
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0264 0.0464 0.0462
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0147 0.0251
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0051 0.006 0.0102
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0105 0.0163 0.0277
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Brugia malayi AKH receptor 0.0702 0.1292 0.1292
Brugia malayi Cytochrome P450 family protein 0.0091 0.0137 0.0137
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0038 0.0038
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0023 0.0008 0.0075
Echinococcus multilocularis serotonin receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.002 0.0001 0.0014
Mycobacterium tuberculosis Probable dehydrogenase 0.0664 0.122 0.1219
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0091 0.0091
Echinococcus multilocularis muscleblind protein 1 0.0147 0.0243 0.0243
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0037 0.0035 0.0035
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0101 0.0101
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0031 0.0023 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.008 0.008
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0107 0.0181
Brugia malayi nuclear receptor NHR-88 0.0076 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0553 0.101 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0002
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) nuclear receptor NHR-67 0.0036 0.0032 0.0032
Toxoplasma gondii cathepsin CPL 0.0024 0.0009 0.0015
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0101 0.0155 0.0264
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.002
Onchocerca volvulus 0.003 0.0021 0.0113
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.003 0.0021 0.002
Echinococcus granulosus dna polymerase kappa 0.0074 0.0103 0.0103
Leishmania major NADH dehydrogenase, putative 0.0027 0.0015 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0024 0.0024
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.003 0.0021 0.0113
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0155 0.0155
Brugia malayi hypothetical protein 0.004 0.004 0.004
Onchocerca volvulus 0.0702 0.1292 0.6993
Brugia malayi Serotonin receptor 0.0702 0.1292 0.1292
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0031 0.0022 0.0037
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0041 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0018 0.0028
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0219
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0021 0.0003 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Trypanosoma cruzi oxidoreductase-like protein, putative 0.003 0.0021 0.0035
Trichomonas vaginalis ap endonuclease, putative 0.0098 0.0149 0.1474
Onchocerca volvulus 0.003 0.0021 0.0113
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0008 0.0077
Loa Loa (eye worm) norepinephrine transporter 0.0584 0.1068 0.1068
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0081 0.0118 0.1608
Onchocerca volvulus 0.0076 0.0108 0.0584
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0702 0.1292 0.1292
Toxoplasma gondii oxidoreductase, putative 0.003 0.0021 0.0035
Onchocerca volvulus 0.0061 0.008 0.0435
Trypanosoma brucei unspecified product 0.0033 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0218 0.0377 0.0377
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0008 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0047 0.0461
Onchocerca volvulus 0.0023 0.0007 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0084 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0112 0.0177 0.0177
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0021 0.0019
Schistosoma mansoni opsin-like receptor 0.0702 0.1292 0.1292
Mycobacterium ulcerans hypothetical protein 0.0023 0.0008 0.0006
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Brugia malayi ecdysteroid receptor 0.0076 0.0108 0.0108
Onchocerca volvulus 0.0027 0.0016 0.0087
Echinococcus multilocularis muscleblind protein 0.0147 0.0243 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0024 0.0024
Echinococcus multilocularis 0.0023 0.0008 0.0008
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.003 0.0021 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0015 0.0023
Schistosoma mansoni dihydropteridine reductase 0.0021 0.0003 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Brugia malayi hypothetical protein 0.0023 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.003 0.0021 0.0034
Schistosoma mansoni inositol monophosphatase 0.0039 0.0038 0.0038
Plasmodium falciparum ferrodoxin reductase-like protein 0.0027 0.0015 0.0024
Plasmodium vivax peroxiredoxin, putative 0.0084 0.0123 0.0208
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0021 0.0003 0.0001
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.003 0.0021 0.0033
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) TK/ROR protein kinase 0.0082 0.012 0.012
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0098 0.0149 0.0147
Trichomonas vaginalis set domain proteins, putative 0.047 0.0852 0.844
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0218 0.0377 0.0377
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0027 0.0015 0.0015
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0014 0.0014
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0003 0.0002
Onchocerca volvulus 0.003 0.0021 0.0113
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0023 0.0008 0.0014
Leishmania major RNA-editing complex protein MP100, putative 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0233 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0437 0.079 0.079
Brugia malayi Dopamine receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis microtubule associated protein 2 0.1361 0.2537 0.2537
Loa Loa (eye worm) hypothetical protein 0.0584 0.1068 0.1068
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0188 0.032 0.032
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Echinococcus granulosus G protein coupled receptor 139 0.0702 0.1292 0.1292
Plasmodium vivax ferrodoxin reductase, putative 0.0027 0.0015 0.0024
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0031 0.0022 0.0037
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0664 0.122 0.1219
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0015 0.0015
Schistosoma mansoni DNA helicase recq5 0.0037 0.0035 0.0035
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0101 0.0155 0.0155
Schistosoma mansoni tar DNA-binding protein 0.0188 0.032 0.032
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0023 0.0007 0.0007
Brugia malayi Trypsin family protein 0.0023 0.0007 0.0007
Brugia malayi hypothetical protein 0.003 0.0021 0.0021
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable hydrolase 0.0218 0.0377 0.0376
Onchocerca volvulus Arrow homolog 0.0027 0.0014 0.0078
Brugia malayi Dehydrogenases, short chain protein 2 0.003 0.0021 0.0021
Brugia malayi intermediate filament protein 0.0054 0.0066 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0218 0.0377 0.3734
Schistosoma mansoni intermediate filament proteins 0.0054 0.0066 0.0066
Entamoeba histolytica hypothetical protein 0.0261 0.0457 0.6228
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.006 0.0079 0.0134
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0038 0.0035 0.0035
Brugia malayi hypothetical protein 0.0036 0.0033 0.0033
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0403 0.0726 0.0726
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0007
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0031 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0261 0.0457 0.6228
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0209 0.0356
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.003 0.0021 0.002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0015 0.0147
Onchocerca volvulus 0.0218 0.0377 0.2041
Onchocerca volvulus 0.0048 0.0054 0.0293
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0027 0.0015 0.0015
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0023 0.0008 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Chlamydia trachomatis endonuclease IV 0.0076 0.0107 0.0104
Echinococcus multilocularis g protein coupled receptor 0.0702 0.1292 0.1292
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.004 0.004
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0023 0.0008 0.0008
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0031 0.0022 0.0219
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0209 0.0209
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0048 0.0056 0.0094
Trichomonas vaginalis fk506 binding protein, putative 0.0023 0.0008 0.0081
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.011 0.0172 0.0172
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0066 0.0066
Onchocerca volvulus 0.005 0.0058 0.0314
Onchocerca volvulus 0.0584 0.1068 0.5784
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.017 0.0285 0.2826
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Toxoplasma gondii hypothetical protein 0.0036 0.0032 0.0054
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0076 0.0108 0.0108
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0027 0.0015 0.0202
Echinococcus multilocularis G-protein coupled receptor, putative 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0023 0.0008 0.0044
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Echinococcus granulosus Mastin 0.0023 0.0007 0.0007
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0035 0.0035
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0044 0.0073
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.003 0.0021 0.0034
Onchocerca volvulus Putative neutral sphingomyelinase 0.002 0.0001 0.0008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Echinococcus granulosus caspase 0.0115 0.0182 0.0182
Onchocerca volvulus 0.005 0.0058 0.0314
Schistosoma mansoni hypothetical protein 0.0303 0.0538 0.0538
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0044 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Onchocerca volvulus Folate transporter 1 homolog 0.005 0.0058 0.0314
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0076 0.0108 0.0108
Leishmania major cathepsin L-like protease 0.0024 0.0009 0.0015
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Plasmodium vivax amine transporter, putative 0.0099 0.0152 0.0257
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0027 0.0015 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0261 0.0457 0.0457
Brugia malayi Cytochrome P450 family protein 0.003 0.0021 0.0021
Leishmania major cathepsin L-like protease 0.0024 0.0009 0.0015
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0114 0.0113
Mycobacterium tuberculosis Possible oxidoreductase 0.003 0.0021 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0076 0.0108 0.0108
Brugia malayi RNA, U transporter 1 0.0081 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0702 0.1292 0.6993
Brugia malayi Dihydrofolate reductase 0.5307 1 1
Leishmania major hypothetical protein, conserved 0.0027 0.0015 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0014
Toxoplasma gondii V-type H(+)-translocating pyrophosphatase VP1 0.0331 0.0589 0.1005
Schistosoma mansoni hypothetical protein 0.0261 0.0457 0.0457
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0016 0.0016
Schistosoma mansoni neuropeptide receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0038 0.0038
Toxoplasma gondii kringle domain-containing protein 0.0082 0.012 0.0204
Loa Loa (eye worm) hypothetical protein 0.0034 0.0028 0.0028
Mycobacterium ulcerans oxidoreductase 0.0021 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Schistosoma mansoni lamin 0.0054 0.0066 0.0066
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0067 0.0067
Brugia malayi nuclear receptor NHR-67 0.0036 0.0032 0.0032
Schistosoma mansoni retinal dehydrogenase 0.003 0.0021 0.0021
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0015 0.0147
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0702 0.1292 0.1292
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0023 0.0007 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Trypanosoma cruzi vacuolar-type proton translocating pyrophosphatase 1 0.0331 0.0589 0.1005
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0022 0.0219
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.3119 0.5861 1
Schistosoma mansoni cpg binding protein 0.0126 0.0203 0.0203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Leishmania major cathepsin L-like protease 0.0024 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0024 0.0009 0.0009
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0249 0.0436 0.0743
Leishmania major hypothetical protein, conserved 0.0031 0.0022 0.0037
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.003 0.0021 0.0035
Echinococcus granulosus endonuclease exonuclease phosphatase 0.002 0.0001 0.0001
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0291 0.0515 0.0513
Echinococcus multilocularis dna polymerase kappa 0.0074 0.0103 0.0103
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Echinococcus multilocularis thymidylate synthase 0.0996 0.1847 0.1847
Onchocerca volvulus 0.0023 0.0007 0.0037
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0027 0.0015 0.0013
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.003 0.0021 0.0206
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0019 0.0019
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0035
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0031 0.0022 0.0022
Mycobacterium tuberculosis Soluble secreted antigen Mpt53 precursor 0.0021 0.0005 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0702 0.1292 0.1292
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.003 0.0021 0.0033
Brugia malayi beta-lactamase 0.0218 0.0377 0.0377
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0027 0.0014 0.0014
Echinococcus multilocularis FTZ F1 alpha 0.0076 0.0108 0.0108
Echinococcus granulosus tumor protein p63 0.0677 0.1244 0.1244
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0031 0.0022 0.0022
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0002
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0048 0.0056 0.0092
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Onchocerca volvulus 0.0702 0.1292 0.6993
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.0008 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0076 0.0108 0.0108
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Brugia malayi jmjC domain containing protein 0.0145 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Plasmodium falciparum cysteine repeat modular protein 1 0.0082 0.012 0.0202
Brugia malayi nuclear hormone receptor 0.0036 0.0032 0.0032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Leishmania major short chain dehydrogenase/reductase, putative 0.003 0.0021 0.0035
Leishmania major trypanothione reductase 0.0291 0.0515 0.0878
Schistosoma mansoni biogenic amine (5HT) receptor 0.0702 0.1292 0.1292
Schistosoma mansoni cpg binding protein 0.0119 0.019 0.019
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0066 0.0066
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0169 0.0284 0.0484
Echinococcus multilocularis neutral sphingomyelinase 0.002 0.0001 0.0001
Echinococcus multilocularis transmembrane protease serine 3 0.0023 0.0007 0.0007
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0047 0.0054 0.0054
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0054 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0021 0.0003 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0066 0.0113
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0076 0.0108 0.0108
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0076 0.0108 0.0108
Leishmania major cytochrome p450-like protein 0.003 0.0021 0.0035
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.003 0.0021 0.0033
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0112 0.0177 0.0177
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.011 0.0172 0.0172
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0035 0.0035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.003 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0243 0.0424 0.0424
Trichomonas vaginalis penicillin-binding protein, putative 0.0218 0.0377 0.3734
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0054 0.0054
Echinococcus granulosus lamin 0.0054 0.0066 0.0066
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0021 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0021 0.0035
Brugia malayi Trypsin family protein 0.0023 0.0007 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0702 0.1292 0.1292
Schistosoma mansoni P2X receptor subunit 0.0286 0.0504 0.0504
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.003 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0024 0.0024
Loa Loa (eye worm) jmjC domain-containing protein 0.0552 0.1008 0.1008
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.011 0.0172 0.0172
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0355 0.0636 0.0636
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.003 0.0021 0.0019
Plasmodium vivax vivapain-2 0.0024 0.0009 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0074 0.0103 0.0176
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0702 0.1292 0.1292
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0036 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0111 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0146 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0169 0.0284 0.0284
Trypanosoma brucei DNA polymerase IV, putative 0.0074 0.0103 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0147 0.0147
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0139 0.0227 0.2121
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0169 0.0284 0.3869
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0038 0.0035 0.0481
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0036 0.0033 0.0033
Plasmodium falciparum enoyl-acyl carrier reductase 0.0021 0.0003 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Loa Loa (eye worm) hypothetical protein 0.0145 0.0239 0.0239
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0037 0.0035 0.0058
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0038 0.0065
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0015 0.0151
Brugia malayi hypothetical protein 0.0553 0.101 0.101
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.003 0.0021 0.0019
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0702 0.1292 0.1292
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Echinococcus granulosus serotonin transporter 0.0584 0.1068 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0378 0.374
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0038 0.0063
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Plasmodium falciparum thioredoxin reductase 0.0291 0.0515 0.0877
Brugia malayi Nuclear hormone receptor-like 1 0.0076 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0249 0.0436 0.4314
Brugia malayi conserved hypotetical protein 0.0036 0.0032 0.0032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Brugia malayi Cathepsin L-like precursor 0.0024 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0036 0.0032 0.0032
Leishmania major hypothetical protein, conserved 0.0027 0.0015 0.0024
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0031 0.0022 0.0219
Leishmania major hypothetical protein, conserved 0.003 0.0021 0.0035
Schistosoma mansoni ap endonuclease 0.0098 0.0149 0.0149
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0101 0.0155 0.0155
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0027 0.0016 0.0087
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.003 0.0021 0.0034
Onchocerca volvulus 0.0099 0.0152 0.0821
Loa Loa (eye worm) thioredoxin reductase 0.0291 0.0515 0.0515
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0027 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0145 0.0239 0.0239
Schistosoma mansoni RAR-like nuclear receptor 0.0076 0.0108 0.0108
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0036 0.0033 0.0033
Treponema pallidum sodium- and chloride- dependent transporter 0.0584 0.1068 1
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0039 0.0067
Schistosoma mansoni rab6-interacting 0.0019 0.0001 0.0001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0056 0.0071 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0028 0.0281
Loa Loa (eye worm) neuropeptide F receptor 0.0702 0.1292 0.1292
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0027 0.0015 0.0147
Treponema pallidum thioredoxin 0.0021 0.0005 0.0042
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0038 0.0036
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0027 0.0015 0.0013
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0147 0.0147
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0076 0.0108 0.0108
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0028 0.0153
Loa Loa (eye worm) hypothetical protein 0.0053 0.0064 0.0064
Giardia lamblia Fructose-bisphosphate aldolase 0.0407 0.0734 1
Loa Loa (eye worm) dihydrofolate reductase 0.5307 1 1
Mycobacterium ulcerans short-chain type oxidoreductase 0.003 0.0021 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0038 0.0036 0.0061
Mycobacterium ulcerans short-chain dehydrogenase 0.003 0.0021 0.0019
Brugia malayi beta-lactamase family protein 0.0218 0.0377 0.0377
Mycobacterium tuberculosis Probable reductase 0.0664 0.122 0.1219
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0027 0.0015 0.0202
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0082 0.012 0.0647
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0044 0.0074
Loa Loa (eye worm) hypothetical protein 0.0569 0.1041 0.1041
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0139 0.0227 0.0385
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0015 0.0025
Trichomonas vaginalis peroxiredoxin, putative 0.0021 0.0005 0.0046
Brugia malayi Probable ClpP-like protease 0.0403 0.0726 0.0726
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.003 0.0021 0.0036
Brugia malayi GnHR receptor homolog 0.0702 0.1292 0.1292
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0169 0.0284 0.0284
Mycobacterium leprae POSSIBLE MEMBRANE-ANCHORED THIOREDOXIN-LIKE PROTEIN (THIOL-DISULFIDE INTERCHANGE RELATED PROTEIN) 0.0021 0.0005 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Echinococcus multilocularis 0.003 0.0021 0.0021
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0098 0.0149 0.0149
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.017 0.0285 0.0487
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.003 0.0021 0.0019
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0023 0.0008 0.0014
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0027 0.0015 0.0025
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0054 0.0054
Schistosoma mansoni importin beta-1 0.0028 0.0018 0.0018
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0031 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0007
Schistosoma mansoni carbonyl reductase 0.003 0.0021 0.0021
Brugia malayi Inositol-1 0.0039 0.0038 0.0038
Mycobacterium ulcerans short-chain dehydrogenase 0.003 0.0021 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0029 0.029
Echinococcus granulosus orexin receptor type 2 0.0702 0.1292 0.1292
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0076 0.0108 0.0108
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 0.0725
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Echinococcus multilocularis cpg binding protein 0.0126 0.0203 0.0203
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0066 0.0113
Entamoeba histolytica hypothetical protein 0.003 0.0021 0.0284
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0101 0.0155 0.0152
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0038 0.0035 0.0058
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0101 0.0155 0.0262
Schistosoma mansoni carbon catabolite repressor protein 0.002 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0145 0.0239 0.0239
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0028 0.0281
Echinococcus granulosus neuropeptide receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Brugia malayi jmjC domain containing protein 0.0552 0.1008 0.1008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Trypanosoma brucei DNA polymerase eta, putative 0.0073 0.0101 0.0171
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0027 0.0015 0.0024
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0996 0.1847 0.1847
Schistosoma mansoni blooms syndrome DNA helicase 0.0071 0.0099 0.0099
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Echinococcus granulosus tar DNA binding protein 0.0188 0.032 0.032
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0023 0.0007 0.0007
Plasmodium vivax steroid dehydrogenase, putative 0.003 0.0021 0.0034
Schistosoma mansoni transcription factor btf3 0.0034 0.0029 0.0029
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0021 0.0003 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.006 0.0058
Entamoeba histolytica cysteine protease, putative 0.0024 0.0009 0.0124
Loa Loa (eye worm) FKBP5 protein 0.0169 0.0284 0.0284
Echinococcus multilocularis transcription factor btf3 0.0034 0.0029 0.0029
Leishmania major oxidoreductase-like protein 0.0051 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0082 0.012 0.012
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0702 0.1292 0.1292
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0029 0.0048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Trypanosoma brucei oxidoreductase-like protein 0.0051 0.006 0.01
Mycobacterium tuberculosis Possible oxidoreductase 0.003 0.0021 0.0019
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0169 0.0284 0.0484
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.003 0.0021 0.0035
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0027 0.0015 0.0202
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0027 0.0015 0.0025
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.003 0.0021 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0076 0.0108 0.0108
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.002 0.0001 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0002
Echinococcus granulosus neutral sphingomyelinase 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0664 0.122 0.1219
Leishmania major cathepsin L-like protease 0.0091 0.0135 0.023
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.002 0.0001 0.0001
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0031 0.0022 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0377 0.0643
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0015 0.0147
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0441 0.0799 0.0799
Echinococcus multilocularis somatostatin receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Mycobacterium tuberculosis Conserved protein 0.0218 0.0377 0.0376
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0101 0.0155 0.0263
Echinococcus granulosus pyruvate kinase 0.0034 0.0028 0.0028
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0036
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.3119 0.5861 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Schistosoma mansoni biogenic amine receptor 0.0702 0.1292 0.1292
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0702 0.1292 0.1292
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0024 0.0009 0.0009
Echinococcus granulosus dnaJ subfamily B 0.1268 0.2363 0.2363
Brugia malayi dehydrogenases, short chain protein 9 0.003 0.0021 0.0021
Trichomonas vaginalis glutamate synthase, putative 0.0027 0.0015 0.0147
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Mycobacterium leprae Conserved hypothetical protein 0.003 0.0021 0.0019
Treponema pallidum oxidoreductase 0.0027 0.0015 0.0137
Toxoplasma gondii hypothetical protein 0.0079 0.0114 0.0195
Schistosoma mansoni alpha-1 adrenergic receptor 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0024 0.0009 0.0049
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.003 0.0021 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0047 0.0047
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Brugia malayi hypothetical protein 0.0041 0.0041 0.0041
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0027 0.0014 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0222 0.0383 0.0652
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0016 0.0016
Schistosoma mansoni terminal deoxycytidyl transferase 0.0047 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0134 0.0217 0.0217
Trypanosoma cruzi pantothenate kinase subunit, putative 0.002 0.0003 0.0004
Echinococcus multilocularis carbonyl reductase 1 0.003 0.0021 0.0021
Mycobacterium ulcerans dehydrogenase 0.0027 0.0015 0.0013
Echinococcus multilocularis neuropeptide receptor A26 0.1181 0.2198 0.2198
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0023 0.0007 0.0007
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0054 0.0091
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0066 0.0113
Brugia malayi Trypsin family protein 0.0023 0.0007 0.0007
Brugia malayi RNA binding protein 0.0188 0.032 0.032
Echinococcus granulosus transmembrane protease serine 3 0.0023 0.0007 0.0007
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.011 0.0172 0.1706
Echinococcus multilocularis jumonji domain containing 1A 0.0145 0.0239 0.0239
Echinococcus granulosus neuropeptide Y receptor 0.0702 0.1292 0.1292
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.003 0.0021 0.0019
Mycobacterium ulcerans hypothetical protein 0.0218 0.0377 0.0375
Schistosoma mansoni kinase 0.0049 0.0058 0.0058
Brugia malayi steroid hormone receptor 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0702 0.1292 0.1292
Echinococcus granulosus bloom syndrome protein 0.0091 0.0135 0.0135
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.003 0.0021 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0044 0.0432
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0066 0.0113
Echinococcus granulosus peptide allatostatin:somatostatin 0.0702 0.1292 0.1292
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0023 0.0008 0.0008
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0021 0.0003 0.0004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0117 0.0185 0.0183
Mycobacterium ulcerans putative regulatory protein 0.0079 0.0114 0.0113
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.003 0.0021 0.0019
Schistosoma mansoni loxhd1 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0243 0.0424 0.0424
Schistosoma mansoni retinoic acid receptor RXR 0.0173 0.0292 0.0292
Plasmodium vivax SET domain protein, putative 0.0061 0.008 0.0136
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0038 0.0035 0.0035
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0036 0.0033 0.0033
Echinococcus multilocularis nuclear receptor nhr 48 0.0036 0.0032 0.0032
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Schistosoma mansoni thyroid hormone receptor 0.0076 0.0108 0.0108
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0009 0.0124
Plasmodium falciparum metacaspase-like protein 0.0044 0.0047 0.0078
Leishmania major hypothetical protein, conserved 0.003 0.0021 0.0035
Brugia malayi hypothetical protein 0.0233 0.0405 0.0405
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.003 0.0021 0.0021
Echinococcus multilocularis traf and tnf receptor associated protein 0.002 0.0001 0.0001
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0023 0.0008 0.0008
Brugia malayi Trypsin family protein 0.0111 0.0175 0.0175
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0023 0.0008 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.002 0.0001 0.0014
Brugia malayi hypothetical protein 0.0019 0.0001 0.0001
Leishmania major lanosterol 14-alpha-demethylase, putative 0.003 0.0021 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0027 0.0015 0.0013
Schistosoma mansoni coup transcription factor 0.0076 0.0108 0.0108
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0012 0.0012
Echinococcus multilocularis oxidoreductase 0.003 0.0021 0.0021
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0056 0.0094
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0021 0.0019
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Leishmania major pyruvate kinase 0.0034 0.0028 0.0047
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0169 0.0284 0.3869
Schistosoma mansoni jumonji domain containing protein 0.0545 0.0995 0.0995
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0031 0.0022 0.0219
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0021 0.0003 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Toxoplasma gondii hypothetical protein 0.0202 0.0346 0.059
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0023 0.0007 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0054 0.0054
Brugia malayi follicle stimulating hormone receptor 0.141 0.2631 0.2631
Mycobacterium ulcerans hypothetical protein 0.0027 0.0015 0.0013
Toxoplasma gondii hypothetical protein 0.0139 0.0227 0.0387
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0218 0.0377 0.0376
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0407 0.0734 1
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0021 0.0019
Leishmania major hypothetical protein, conserved 0.003 0.0021 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0076 0.0108 0.0108
Brugia malayi CXXC zinc finger family protein 0.0119 0.019 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Plasmodium vivax ataxin-2 like protein, putative 0.0126 0.0202 0.0343
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0035
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.0197 0.0336 0.0334
Echinococcus multilocularis peptidase Clp (S14 family) 0.0264 0.0464 0.0464
Toxoplasma gondii calcium binding egf domain-containing protein 0.0027 0.0014 0.0024
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0037 0.0504
Leishmania major hypothetical protein, conserved 0.0031 0.0022 0.0037
Plasmodium vivax vacuolar-type H+ pumping pyrophosphatase, putative 0.0331 0.0589 0.1004
Brugia malayi CCR4 0.002 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0051 0.0061 0.0061
Echinococcus multilocularis steroid dehydrogenase 0.003 0.0021 0.0021
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.003 0.0021 0.0019
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0047 0.0047
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0101 0.0155 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0081
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.002 0.0001 0.0014
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0027 0.0015 0.0013
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0021 0.0003 0.0002
Brugia malayi hypothetical protein 0.0036 0.0033 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0197 0.0336 0.0573
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0738 0.1361 0.1359
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0024 0.0009 0.0014
Leishmania major hypothetical protein, conserved 0.002 0.0001 0.0002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.0204 0.0348
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.002 0.0001 0.0001
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0035 0.0035
Brugia malayi ecdysone receptor 0.0036 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0076 0.0108 0.0108
Trichomonas vaginalis DNA polymerase eta, putative 0.0074 0.0103 0.1024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0261 0.0457 0.0457
Echinococcus granulosus tm gpcr rhodopsin 0.0702 0.1292 0.1292
Brugia malayi Reduced folate carrier family protein 0.005 0.0058 0.0058
Echinococcus granulosus neuropeptide s receptor 0.1181 0.2198 0.2198
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0015 0.0147
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0024 0.0009 0.0014
Onchocerca volvulus 0.0099 0.0152 0.0821
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0021 0.0003 0.0004
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0027 0.0015 0.0025
Schistosoma mansoni neuropeptide receptor 0.0702 0.1292 0.1292
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Echinococcus multilocularis enteropeptidase 0.0023 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.003 0.0021 0.0019
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0029 0.0029
Echinococcus multilocularis p2X purinoceptor 4 0.0286 0.0504 0.0504
Toxoplasma gondii redoxin domain-containing protein 0.0084 0.0123 0.0209
Trichomonas vaginalis ap endonuclease, putative 0.0098 0.0149 0.1474
Trichomonas vaginalis peroxiredoxin, putative 0.0021 0.0005 0.0046
Echinococcus multilocularis neuropeptide s receptor 0.1181 0.2198 0.2198
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0023 0.0008 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0209 0.0354
Loa Loa (eye worm) latrophilin receptor protein 2 0.0112 0.0177 0.0177
Brugia malayi putative neuropeptide receptor 0.0702 0.1292 0.1292
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0218 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Schistosoma mansoni hypothetical protein 0.0147 0.0243 0.0243
Onchocerca volvulus 0.0702 0.1292 0.6993
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0021 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0076 0.0108 0.0108
Schistosoma mansoni microtubule-associated protein tau 0.1361 0.2537 0.2537
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0028 0.0048
Brugia malayi Cathepsin L-like precursor 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0145 0.0239 0.0239
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0031 0.0022 0.0219
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0027 0.0015 0.0025
Brugia malayi regulator of G-protein signaling egl-10 0.0025 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Trypanosoma brucei DNA polymerase IV, putative 0.0067 0.0091 0.0153
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.002 0.0001 0.002
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0018 0.0018
Leishmania major mitochondrial DNA polymerase beta 0.0222 0.0383 0.0653
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0023 0.0008 0.0112
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0702 0.1292 0.1292
Brugia malayi nuclear receptor RXR 0.0036 0.0032 0.0032
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.003 0.0021 0.0206
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0218 0.0377 0.0375
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0702 0.1292 0.1292
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0054 0.0054
Toxoplasma gondii hypothetical protein 0.0079 0.0114 0.0195
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Echinococcus multilocularis neuropeptide Y receptor 0.0702 0.1292 0.1292
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0066 0.011
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0031 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0007
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0037 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0021 0.0035
Onchocerca volvulus 0.0702 0.1292 0.6993
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0038 0.0377
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Treponema pallidum NADH oxidase 0.0101 0.0155 0.1449
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Echinococcus multilocularis lysine specific demethylase 5A 0.0545 0.0995 0.0995
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.0049 0.0056 0.0056
Schistosoma mansoni pyruvate kinase 0.0034 0.0028 0.0028
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0702 0.1292 0.1292
Brugia malayi G-protein coupled receptor 0.0702 0.1292 0.1292
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0027 0.0015 0.0013
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0029 0.005
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0251 0.044 0.0438
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0027 0.0015 0.0013
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0014
Entamoeba histolytica short chain dehydrogenase family protein 0.003 0.0021 0.0284
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.002 0.0001 0.0014
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0664 0.122 0.1219
Echinococcus granulosus muscleblind protein 0.0147 0.0243 0.0243
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0066 0.0066
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Plasmodium falciparum DNase I-like protein, putative 0.002 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.003 0.0021 0.0019
Leishmania major cAMP-specific phosphodiesterase, putative 0.0031 0.0022 0.0037
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0403 0.0726 0.1239
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0047 0.0461
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0003 0.0003
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0016 0.0087
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0029 0.0399
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0355 0.0636 0.0636
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0152
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0035 0.035
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0074 0.0104 0.0104
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Echinococcus multilocularis lysine specific demethylase 6a 0.0145 0.0239 0.0239
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0025 0.0012 0.0012
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0227 0.0227
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0028 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Loa Loa (eye worm) RecQ helicase 0.0091 0.0135 0.0135
Trypanosoma brucei pteridine reductase 1 0.0479 0.087 0.1482
Schistosoma mansoni P2X receptor subunit 0.0286 0.0504 0.0504
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0009 0.0009
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.003 0.0021 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.003 0.0021 0.0021
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0702 0.1292 0.1292
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0001
Giardia lamblia NADH oxidase lateral transfer candidate 0.0101 0.0155 0.2095
Loa Loa (eye worm) PDE1B protein 0.0031 0.0022 0.0022
Echinococcus granulosus JmjC domain containing protein 4 0.0145 0.0239 0.0239
Brugia malayi TAR-binding protein 0.0188 0.032 0.032
Echinococcus granulosus microtubule associated protein 2 0.1361 0.2537 0.2537
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0355 0.0636 0.0636
Brugia malayi larval opioid receptor 0.0702 0.1292 0.1292
Brugia malayi Cathepsin L-like precursor 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0082 0.012 0.012
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.002 0.0001 0.0002
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0023 0.0008 0.0012
Loa Loa (eye worm) inositol-1 0.0039 0.0038 0.0038
Schistosoma mansoni pyruvate kinase 0.0034 0.0028 0.0028
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0152 0.0252 0.0252
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0036
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0133 0.0216 0.0216
Plasmodium falciparum thioredoxin reductase 0.0101 0.0155 0.0263
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.002 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.003 0.0021 0.0019
Mycobacterium tuberculosis Probable esterase LipL 0.0218 0.0377 0.0376
Mycobacterium tuberculosis Probable lipase LipD 0.0218 0.0377 0.0376
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0041 0.0042 0.0042
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.0204 0.0349
Leishmania major vacuolar-type proton translocating pyrophosphatase 1, putative 0.0331 0.0589 0.1005
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.003 0.0021 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0076 0.0108 0.0108
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.003 0.0021 0.0035
Giardia lamblia Thioredoxin reductase 0.0027 0.0015 0.0182
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0584 0.1068 0.1068
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0702 0.1292 0.1292
Echinococcus granulosus 7TM GPCR rhodopsin 0.0702 0.1292 0.1292
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0155 0.0155
Schistosoma mansoni jumonji/arid domain-containing protein 0.0552 0.1008 0.1008
Entamoeba histolytica short chain dehydrogenase family protein 0.003 0.0021 0.0284
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.003 0.0021 0.0019
Echinococcus multilocularis RUN 0.0019 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Echinococcus granulosus tissue type plasminogen activator 0.0082 0.012 0.012
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0111 0.0175 0.0175
Trichomonas vaginalis immunophilin, putative 0.0169 0.0284 0.2814
Echinococcus granulosus g protein coupled receptor 0.0702 0.1292 0.1292
Leishmania major metacaspase, putative 0.0044 0.0047 0.0079
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0031 0.0022 0.0022
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0038 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.003 0.0021 0.002
Leishmania major pteridine reductase 1 0.0509 0.0926 0.158
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0014
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0145 0.0239 0.0405
Plasmodium vivax hypothetical protein, conserved 0.003 0.0021 0.0034
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0003 0.0002
Brugia malayi Thioredoxin reductase 0.0291 0.0515 0.0515
Echinococcus multilocularis bloom syndrome protein 0.0091 0.0135 0.0135
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0169 0.0284 0.0284
Echinococcus multilocularis thioredoxin glutathione reductase 0.0291 0.0515 0.0515
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0054 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0147 0.0243 0.0243
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0027 0.0015 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0218 0.0377 0.3734
Echinococcus granulosus dna polymerase eta 0.0073 0.0101 0.0101
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0038 0.0038
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0013
Echinococcus multilocularis lamin 0.0054 0.0066 0.0066
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0152 0.0257
Brugia malayi isocitrate dehydrogenase 0.0048 0.0054 0.0054
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0101 0.0155 0.21
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0204 0.0203
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.002 0.0001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Treponema pallidum folylpolyglutamate synthetase (folC) 0.0197 0.0336 0.3143
Brugia malayi Steroid receptor seven-up type 2 0.0076 0.0108 0.0108
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.003 0.0021 0.0019
Echinococcus multilocularis neuropeptide receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.002 0.0001 0.0014
Leishmania major cytochrome p450-like protein 0.003 0.0021 0.0035
Onchocerca volvulus 0.0024 0.0009 0.0049
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Schistosoma mansoni hypothetical protein 0.0112 0.0177 0.0177
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0008 0.0013
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0021 0.0003 0.0005
Echinococcus multilocularis carbonyl reductase 1 0.003 0.0021 0.0021
Mycobacterium ulcerans ketoacyl reductase 0.003 0.0021 0.0019
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0021 0.0003 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0188 0.032 0.032
Onchocerca volvulus 0.0099 0.0152 0.0821
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0105 0.0163 0.0276
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0702 0.1292 0.1292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0702 0.1292 0.1292
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0027 0.0014 0.0014
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.011 0.0172 0.0172
Toxoplasma gondii selenide, water dikinase 0.0027 0.0015 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0222 0.0383 0.0654
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0009 0.0124
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0052 0.0062 0.0062
Schistosoma mansoni peptidase Clp (S14 family) 0.0403 0.0726 0.0726
Echinococcus multilocularis allatostatin A receptor 0.0702 0.1292 0.1292
Brugia malayi folate-like transporter 3 0.005 0.0058 0.0058
Echinococcus granulosus neuropeptide FF receptor 2 0.0702 0.1292 0.1292
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0002 0.0009
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.003 0.0021 0.0284
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0029 0.0048
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Plasmodium falciparum GAF domain-related protein, putative 0.0079 0.0114 0.0194
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.003 0.0021 0.0113
Loa Loa (eye worm) beta-lactamase 0.0218 0.0377 0.0377
Schistosoma mansoni sodium/chloride dependent transporter 0.0099 0.0152 0.0152
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0037 0.0037
Plasmodium vivax hypothetical protein, conserved 0.002 0.0001 0.0001
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0251 0.044 0.044
Brugia malayi nuclear hormone receptor family member nhr-6 0.0036 0.0032 0.0032
Plasmodium falciparum V-type K+-independent H+-translocating inorganic pyrophosphatase 0.0331 0.0589 0.1004
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0702 0.1292 0.1292
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0219
Schistosoma mansoni biogenic amine receptor 0.0702 0.1292 0.1292
Schistosoma mansoni hypothetical protein 0.003 0.0021 0.0021
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0027 0.0015 0.0162
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0146 0.024 0.024
Toxoplasma gondii NADPH-glutathione reductase 0.0101 0.0155 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0008 0.0012
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Brugia malayi hypothetical protein 0.0081 0.0118 0.0118
Toxoplasma gondii hypothetical protein 0.0099 0.0152 0.0258
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0112 0.0177 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0022 0.0037
Brugia malayi RNA recognition motif domain containing protein 0.0188 0.032 0.032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0015 0.0151
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0012
Trypanosoma brucei protein kinase, putative 0.0054 0.0066 0.0111
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0023 0.0008 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0099 0.0152 0.0152
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0249 0.0436 0.0436
Echinococcus granulosus alpha 1A adrenergic receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.008 0.0137
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.003 0.0021 0.0019
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.003 0.0021 0.0019
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Trypanosoma brucei short-chain dehydrogenase, putative 0.003 0.0021 0.0033
Leishmania major C-8 sterol isomerase-like protein 0.0374 0.0672 0.1145
Treponema pallidum fructose-bisphosphate aldolase 0.0407 0.0734 0.6872
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Leishmania major cathepsin L-like protease 0.0091 0.0135 0.023
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0099 0.0168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0218 0.0377 0.3734
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0074 0.0103 0.0176
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0056 0.0056
Echinococcus granulosus enteropeptidase 0.0023 0.0007 0.0007
Trypanosoma brucei Metacaspase-4 0.0044 0.0047 0.0077
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.011 0.0172 0.0172
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni nuclear hormone receptor 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Leishmania major cathepsin L-like protease 0.0024 0.0009 0.0015
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0139 0.0227 0.0385
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.003 0.0021 0.0019
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0079 0.0114 0.0113
Schistosoma mansoni caspase-3 (C14 family) 0.0115 0.0182 0.0182
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0027 0.0015 0.0015
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Echinococcus multilocularis orexin receptor type 2 0.0702 0.1292 0.1292
Plasmodium falciparum ataxin-2 like protein, putative 0.0126 0.0202 0.0343
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0738 0.1361 0.1359
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0066 0.0113
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0147 0.0243 0.0243
Giardia lamblia Hypothetical protein 0.0023 0.0008 0.0092
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0197 0.0336 0.3326
Loa Loa (eye worm) hypothetical protein 0.0147 0.0243 0.0243
Onchocerca volvulus 0.0702 0.1292 0.6993
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0584 0.1068 0.1068
Schistosoma mansoni tar DNA-binding protein 0.0188 0.032 0.032
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0066 0.0066
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0001 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0076 0.0108 0.0108
Echinococcus multilocularis aryl hydrocarbon receptor 0.0052 0.0062 0.0062
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0047 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus multilocularis serotonin transporter 0.0584 0.1068 0.1068
Onchocerca volvulus 0.0027 0.0016 0.0087
Echinococcus granulosus carbonyl reductase 1 0.003 0.0021 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0015 0.0151
Loa Loa (eye worm) cytochrome P450 family protein 0.0091 0.0137 0.0137
Onchocerca volvulus 0.003 0.0021 0.0113
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0027 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0218 0.0377 0.0376
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0054 0.0054
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0054 0.0091
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Plasmodium falciparum exodeoxyribonuclease III, putative 0.002 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.002 0.0001 0.0001
Leishmania major dihydrofolate reductase-thymidylate synthase 0.3119 0.5861 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Loa Loa (eye worm) hypothetical protein 0.0218 0.0377 0.0377
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0027 0.0015 0.0015
Echinococcus granulosus glycoprotein Antigen 5 0.0023 0.0007 0.0007
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0169 0.0284 0.0284
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.004 0.004 0.004
Onchocerca volvulus 0.0023 0.0007 0.0037
Leishmania major hypothetical protein, conserved 0.002 0.0001 0.0002
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0152 0.0252 0.0252
Schistosoma mansoni nocturnin 0.002 0.0001 0.0001
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0169 0.0284 0.0484
Schistosoma mansoni hypothetical protein 0.0048 0.0054 0.0054
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0038 0.0518
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0035 0.0059
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0027 0.0015 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0076 0.0108 0.0108
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0103 0.0103
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0251 0.044 0.0438
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0264 0.0464 0.0462
Echinococcus multilocularis synaptojanin 1 0.002 0.0001 0.0001
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0056 0.0071 0.0071
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0234 0.0234
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0249 0.0436 0.0436
Trypanosoma cruzi NADH dehydrogenase, putative 0.0027 0.0015 0.0025
Schistosoma mansoni opsin-like receptor 0.0702 0.1292 0.1292
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trypanosoma brucei hypothetical protein, conserved 0.0218 0.0377 0.0641
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Loa Loa (eye worm) acetyltransferase 0.0143 0.0234 0.0234
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0107 0.0181
Echinococcus granulosus GPCR family 2 0.0112 0.0177 0.0177
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.002 0.0001 0.0001
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0015 0.0024
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Echinococcus granulosus expressed protein 0.0368 0.066 0.066
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0038 0.0038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0076 0.0108 0.0584
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0249 0.0436 0.0436
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0035 0.006
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0001 0.0001
Trypanosoma cruzi folylpolyglutamate synthetase 0.0197 0.0336 0.0573
Onchocerca volvulus 0.002 0.0001 0.0008
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0027 0.0015 0.0162
Schistosoma mansoni myosin xvIII 0.0702 0.1292 0.1292
Schistosoma mansoni hypothetical protein 0.0702 0.1292 0.1292
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Echinococcus multilocularis JmjC domain containing protein 4 0.0145 0.0239 0.0239
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0003 0.0003
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0027 0.0015 0.0024
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0036 0.0032 0.0032
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0702 0.1292 0.1292
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.008 0.008
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.003 0.0021 0.0019
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0553 0.101 0.1723
Leishmania major biopterin transporter, putative;with=GeneDB:LinJ35_V3.5120 0.0437 0.0791 0.1349
Schistosoma mansoni lozenge 0.0055 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0702 0.1292 0.1292
Schistosoma mansoni caspase-7 (C14 family) 0.0084 0.0123 0.0123
Plasmodium falciparum phosphodiesterase delta, putative 0.0031 0.0022 0.0036
Echinococcus granulosus oxidoreductase 0.003 0.0021 0.0021
Onchocerca volvulus 0.0996 0.1847 1
Onchocerca volvulus 0.0054 0.0066 0.0356
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0052 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Brugia malayi Cathepsin L-like precursor 0.0024 0.0009 0.0009
Plasmodium vivax JmjC domain containing protein 0.0145 0.0239 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0029 0.029
Brugia malayi hypothetical protein 0.0261 0.0457 0.0457
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.003 0.0021 0.0284
Chlamydia trachomatis dihydrofolate reductase 0.5307 1 1
Echinococcus multilocularis carbonyl reductase 1 0.003 0.0021 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Echinococcus granulosus snurportin 1 0.0303 0.0538 0.0538
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.003 0.0021 0.0021
Mycobacterium tuberculosis Conserved protein 0.0218 0.0377 0.0376
Entamoeba histolytica deoxycytidyl transferase, putative 0.0047 0.0054 0.0734
Echinococcus granulosus geminin 0.1525 0.2849 0.2849
Echinococcus granulosus ecdysone induced protein 78C 0.0076 0.0108 0.0108
Trichomonas vaginalis fk506-binding protein, putative 0.0023 0.0008 0.0081
Loa Loa (eye worm) oxidoreductase 0.0021 0.0003 0.0003
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0101 0.0155 0.0155
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0204 0.0204
Trypanosoma brucei short-chain dehydrogenase, putative 0.003 0.0021 0.0033
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Toxoplasma gondii melibiase subfamily protein 0.0101 0.0155 0.0264
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0015 0.0151
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0022 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Brugia malayi prostaglandin transporter 0.0027 0.0016 0.0016
Onchocerca volvulus Neuropeptide F receptor homolog 0.0702 0.1292 0.6993
Echinococcus granulosus neuropeptides capa receptor 0.0702 0.1292 0.1292
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0047 0.0078
Leishmania major hypothetical protein, conserved 0.0218 0.0377 0.0643
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0702 0.1292 0.1292
Onchocerca volvulus 0.002 0.0001 0.0008
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0152
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0021 0.0003 0.0005
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0016 0.0027
Schistosoma mansoni phosphatidylserine receptor 0.0145 0.0239 0.0239
Loa Loa (eye worm) G-protein coupled receptor 0.0702 0.1292 0.1292
Echinococcus granulosus caspase 8 0.0044 0.0047 0.0047
Echinococcus granulosus FK506 binding protein 2 0.0023 0.0008 0.0008
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0009 0.0049
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0015 0.0015
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0664 0.122 0.1219
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0169 0.0284 0.0483
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0091 0.0906
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0169 0.0284 0.2814
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.003 0.0021 0.002
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0028 0.0048
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.003 0.0021 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Toxoplasma gondii calcium binding egf domain-containing protein 0.0027 0.0014 0.0024
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.0538 0.0538
Trypanosoma cruzi short-chain dehydrogenase, putative 0.003 0.0021 0.0035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Schistosoma mansoni amine GPCR 0.0702 0.1292 0.1292
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.011 0.0172 0.1706
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.002
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0035 0.0035
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0027 0.0015 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0076 0.0108 0.0108
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Brugia malayi Dopamine receptor protein 1 0.0702 0.1292 0.1292
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.011 0.0172 0.0172
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0028 0.0153
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.004
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0105 0.0163 0.0275
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Loa Loa (eye worm) serotonin transporter b 0.0584 0.1068 0.1068
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0702 0.1292 0.1292
Schistosoma mansoni hypothetical protein 0.0027 0.0015 0.0015
Schistosoma mansoni neuropeptide f receptor 76f 0.0702 0.1292 0.1292
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium ulcerans thiol peroxidase 0.0021 0.0005 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0702 0.1292 0.1292
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0249 0.0436 0.0743
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0249 0.0436 0.4314
Trypanosoma cruzi DNA polymerase kappa, putative 0.0074 0.0103 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0377 0.0643
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.002 0.0001 0.0001
Onchocerca volvulus 0.005 0.0058 0.0314
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Brugia malayi neuropeptide F receptor 0.0702 0.1292 0.1292
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.008 0.0115 0.0194
Toxoplasma gondii cytochrome p450 superfamily protein 0.003 0.0021 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0076 0.0108 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Leishmania major importin beta-1 subunit, putative 0.0023 0.0008 0.0012
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0139 0.0227 0.0225
Echinococcus granulosus lysine specific demethylase 6a 0.0145 0.0239 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.008 0.008
Schistosoma mansoni tar DNA-binding protein 0.0188 0.032 0.032
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0197 0.0336 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0029 0.029
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0169 0.0284 0.3857
Loa Loa (eye worm) hypothetical protein 0.0079 0.0114 0.0114
Schistosoma mansoni histamine h1 receptor 0.0702 0.1292 0.1292
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0021 0.0004 0.0007
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.3119 0.5861 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0054 0.0054
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0047 0.0054 0.0054
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.002 0.0001 0.002
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0197 0.0336 0.1818
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0076 0.0108 0.0108
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0101 0.0155 0.0262
Brugia malayi Muscleblind-like protein 0.0147 0.0243 0.0243
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0103 0.0103
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Onchocerca volvulus Cathepsin F homolog 0.0024 0.0009 0.0049
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.002 0.0001 0.0002
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0027 0.0015 0.0024
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0081 0.0118 0.1608
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0028 0.0028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0098 0.0149 0.0254
Trichomonas vaginalis DNA helicase recq, putative 0.0091 0.0135 0.134
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0031 0.0022 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Schistosoma mansoni DNA polymerase eta 0.0073 0.0101 0.0101
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0702 0.1292 0.1292
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0218 0.0377 0.0377
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0146 0.024 0.024
Schistosoma mansoni folylpolyglutamate synthase 0.0197 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0101 0.0155 0.0153
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0175 0.0175
Loa Loa (eye worm) CXXC zinc finger family protein 0.0119 0.019 0.019
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0152
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0098 0.0149 0.2016
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0066 0.0113
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0258
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0016 0.0028
Trichomonas vaginalis steroid dehydrogenase, putative 0.003 0.0021 0.0206
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0066 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0702 0.1292 0.1292
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0107 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0015 0.0151
Schistosoma mansoni sodium-dependent amino acid transporter 0.0099 0.0152 0.0152
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0204 0.0203
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0015 0.0151
Chlamydia trachomatis thioredoxin reductase 0.0027 0.0015 0.0012
Leishmania major hypothetical protein, conserved 0.0145 0.0239 0.0407
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0702 0.1292 0.1292
Echinococcus granulosus g-protein coupled receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis retinol dehydrogenase 11 0.003 0.0021 0.0021
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.003 0.0021 0.0035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Onchocerca volvulus 0.0702 0.1292 0.6993
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Schistosoma mansoni P2X receptor subunit 0.0286 0.0504 0.0504
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.002 0.0001 0.0014
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Onchocerca volvulus 0.0702 0.1292 0.6993
Brugia malayi Melibiase family protein 0.0067 0.0091 0.0091
Loa Loa (eye worm) RNA binding protein 0.0188 0.032 0.032
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0009 0.0009
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0048 0.0056 0.0095
Echinococcus granulosus carbonyl reductase 1 0.003 0.0021 0.0021
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0001 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0251 0.044 0.0438
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0066 0.0887
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0027 0.0015 0.0015
Echinococcus multilocularis steroid dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0076 0.0108 0.0108
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0027 0.0015 0.0147
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.0197 0.0336 0.0334
Echinococcus granulosus neuropeptide receptor A26 0.1181 0.2198 0.2198
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.003 0.0021 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Brugia malayi hypothetical protein 0.0099 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium tuberculosis Hypothetical protein 0.0553 0.101 0.1009
Mycobacterium ulcerans short chain dehydrogenase 0.0051 0.006 0.0058
Leishmania major cathepsin L-like protease 0.0024 0.0009 0.0015
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0066 0.0066
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0101 0.0155 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.003 0.0021 0.002
Brugia malayi glutathione reductase 0.0291 0.0515 0.0515
Giardia lamblia Reductase, putative 0.003 0.0021 0.0265
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0051 0.006 0.0058
Brugia malayi jmjC domain containing protein 0.0545 0.0995 0.0995
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0031 0.0022 0.0282
Toxoplasma gondii LsmAD domain-containing protein 0.0126 0.0202 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0047 0.0461
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0031 0.0022 0.0219
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0145 0.0239 0.0407
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.003 0.0021 0.0284
Trichomonas vaginalis peroxiredoxin, putative 0.0021 0.0005 0.0046
Schistosoma mansoni lamin 0.0054 0.0066 0.0066
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0015 0.0015
Entamoeba histolytica recQ family DNA helicase 0.0019 0 0.0002
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0071 0.0071
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0031 0.0022 0.0219
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0076 0.0108 0.0108
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.003 0.0021 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.003 0.0021 0.002
Toxoplasma gondii hypothetical protein 0.0099 0.0152 0.0258
Schistosoma mansoni disulfide oxidoreductase 0.0027 0.0015 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Leishmania major cathepsin L-like protease 0.0091 0.0135 0.023
Onchocerca volvulus 0.0218 0.0377 0.2041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Echinococcus multilocularis cysteine protease 0.0024 0.0009 0.0009
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) glutaminase 2 0.0537 0.098 0.098
Schistosoma mansoni steroid dehydrogenase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.003 0.0021 0.0019
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0023 0.0008 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Schistosoma mansoni sodium/chloride dependent transporter 0.0584 0.1068 0.1068
Brugia malayi tailless protein 0.0036 0.0032 0.0032
Leishmania major quinonoid dihydropteridine reductase 0.003 0.0021 0.0035
Brugia malayi polk-prov protein 0.0041 0.0042 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.012 0.0204
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Schistosoma mansoni cript-related 0.002 0.0001 0.0001
Echinococcus multilocularis phd:f box containing protein 0.0145 0.0239 0.0239
Entamoeba histolytica hypothetical protein 0.0034 0.0029 0.0399
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0035
Loa Loa (eye worm) dehydrogenase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0313 0.0555 0.0555
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0001
Echinococcus granulosus transcription factor btf3 0.0034 0.0029 0.0029
Echinococcus multilocularis tumor protein p63 0.0677 0.1244 0.1244
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0654 0.12 0.1199
Echinococcus multilocularis geminin 0.1525 0.2849 0.2849
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.003 0.0021 0.0206
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0702 0.1292 0.1292
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0047 0.0079
Echinococcus multilocularis folate receptor beta 0.0821 0.1516 0.1516
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0027 0.0014 0.0014
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.3119 0.5861 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0025 0.0012 0.0012
Echinococcus granulosus peptidase Clp S14 family 0.0264 0.0464 0.0464
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0054 0.0054
Leishmania major hypothetical protein, conserved 0.0126 0.0202 0.0343
Onchocerca volvulus 0.0054 0.0066 0.0356
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.003 0.0021 0.0035
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0145 0.0239 0.0407
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.003 0.0021 0.002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0441 0.0799 0.0799
Echinococcus granulosus tachykinin peptides receptor 99D 0.0702 0.1292 0.1292
Loa Loa (eye worm) trypsin family protein 0.0023 0.0007 0.0007
Echinococcus multilocularis fk506 binding protein 0.0169 0.0284 0.0284
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0022 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0021 0.0003 0.0001
Echinococcus granulosus carbonyl reductase 1 0.003 0.0021 0.0021
Giardia lamblia Short-chain dehydrogenase, putative 0.003 0.0021 0.0265
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0702 0.1292 0.1292
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.003 0.0021 0.0265
Echinococcus multilocularis carbonyl reductase 1 0.003 0.0021 0.0021
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0106 0.0106
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0027 0.0015 0.0013
Trypanosoma brucei short-chain dehydrogenase, putative 0.003 0.0021 0.0033
Brugia malayi hypothetical protein 0.1762 0.3296 0.3296
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.003 0.0021 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0001
Brugia malayi Pre-SET motif family protein 0.0413 0.0745 0.0745
Leishmania major hypothetical protein, conserved 0.0082 0.012 0.0203
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0403 0.0726 0.0726
Onchocerca volvulus 0.0023 0.0008 0.0044
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0147 0.2003
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0114 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0023 0.0007 0.0007
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0027 0.0015 0.0025
Onchocerca volvulus Folate transporter 1 homolog 0.005 0.0058 0.0314
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0099 0.0152 0.0152
Plasmodium falciparum ataxin-2 like protein, putative 0.0126 0.0202 0.0343
Onchocerca volvulus 0.0024 0.0009 0.0049
Loa Loa (eye worm) cysteine protease 0.0024 0.0009 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0032 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0066 0.0066
Toxoplasma gondii carbonyl reductase 1, putative 0.003 0.0021 0.0035
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0054 0.0054
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0051 0.006 0.0102
Onchocerca volvulus 0.0024 0.0009 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.003 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor 0.0036 0.0032 0.0032
Brugia malayi putative neuropeptide receptor NPR1 0.0702 0.1292 0.1292
Trichomonas vaginalis glutathione reductase, putative 0.0101 0.0155 0.1535
Brugia malayi beta-NAC-like protein 0.0034 0.0029 0.0029
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0074 0.0104 0.0104
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0036 0.0033 0.0033
Echinococcus granulosus aryl hydrocarbon receptor 0.0052 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Onchocerca volvulus 0.012 0.0191 0.1036
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0021 0.0003 0.0002
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0035
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0098 0.0149 0.0149
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0101 0.0155 0.0262
Echinococcus granulosus hypothetical protein 0.003 0.0021 0.0021
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Brugia malayi hypothetical protein 0.0052 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0027 0.0015 0.0015
Trypanosoma cruzi cruzipain precursor, putative 0.0091 0.0135 0.0231
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Schistosoma mansoni z-protein (S1r protein) 0.0025 0.0012 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0076 0.0108 0.0108
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.002 0.0001 0.0001
Brugia malayi latrophilin 2 splice variant baaae 0.0243 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0545 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0126 0.0202 0.0202
Brugia malayi Calcitonin receptor-like protein seb-1 0.0355 0.0636 0.0636
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Schistosoma mansoni egf-like domain protein 0.0027 0.0014 0.0014
Brugia malayi Bloom's syndrome protein homolog 0.0091 0.0135 0.0135
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0027 0.0015 0.0013
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0101 0.0155 0.0264
Trichomonas vaginalis apoptosis inducing factor, putative 0.0027 0.0015 0.0147
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.003 0.0021 0.0019
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0234 0.0234
Echinococcus granulosus laminin 0.0027 0.0014 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0441 0.0799 0.0799
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0218 0.0377 0.0377
Trypanosoma brucei metacaspase MCA3 0.0044 0.0047 0.0077
Echinococcus granulosus synaptojanin 1 0.002 0.0001 0.0001
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0101 0.0155 0.0153
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0407 0.0734 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Giardia lamblia Kinase, PLK 0.0097 0.0147 0.1987
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0024 0.0024
Mycobacterium ulcerans esterase/lipase LipP 0.0218 0.0377 0.0375
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.002 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Schistosoma mansoni synaptojanin 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0101 0.0155 0.0154
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.002 0.0001 0.0001
Echinococcus multilocularis pyruvate kinase 0.0027 0.0015 0.0015
Onchocerca volvulus 0.005 0.0058 0.0314
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0219
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.003 0.0021 0.0035
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0015 0.0147
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0023 0.0008 0.0013
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0036 0.0033 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0152
Mycobacterium ulcerans oxidoreductase 0.003 0.0021 0.0019
Brugia malayi Latrophilin receptor protein 2 0.0112 0.0177 0.0177
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0054 0.0066 0.0112
Echinococcus multilocularis Tolloid protein 1 0.0027 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Brugia malayi nuclear receptor RXR 0.004 0.004 0.004
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.003 0.0021 0.0021
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0054 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.5307 1 1
Loa Loa (eye worm) thymidylate synthase 0.0996 0.1847 0.1847
Giardia lamblia Hypothetical protein 0.0031 0.0022 0.0282
Loa Loa (eye worm) reduced folate carrier family protein 0.005 0.0058 0.0058
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0036
Schistosoma mansoni immunophilin 0.0169 0.0284 0.0284
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0147 0.025
Schistosoma mansoni neuropeptide receptor 0.0702 0.1292 0.1292
Leishmania major endonuclease/exonuclease protein-like protein 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0001
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0134 0.0217 0.1173
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Plasmodium falciparum steroid dehydrogenase, putative 0.003 0.0021 0.0034
Schistosoma mansoni growth hormone secretagogue receptor 0.0702 0.1292 0.1292
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0047 0.0461
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0028 0.0027
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0169 0.0284 0.3857
Mycobacterium tuberculosis Probable oxidoreductase 0.0738 0.1361 0.1359
Onchocerca volvulus 0.0019 0.0001 0.0005
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0027 0.0015 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0232 0.0402 0.0686
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0027 0.0014 0.0014
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.003 0.0029
Entamoeba histolytica hypothetical protein 0.0261 0.0457 0.6228
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0021 0.0003 0.0003
Schistosoma mansoni adenoreceptor 0.0702 0.1292 0.1292
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.002 0.0001 0.002
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0027 0.0015 0.0013
Echinococcus granulosus phd:f box containing protein 0.0145 0.0239 0.0239
Onchocerca volvulus 0.0021 0.0003 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0061 0.008 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0021 0.0035
Echinococcus multilocularis regulator of G protein signaling 7 0.0025 0.0012 0.0012
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0082 0.012 0.0202
Onchocerca volvulus 0.0036 0.0032 0.0173
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.003 0.0021 0.0035
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0028 0.0028
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis hypothetical protein 0.0021 0.0003 0.0031
Leishmania major DNA polymerase kappa, putative 0.0054 0.0066 0.0112
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0209 0.0209
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0099 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Brugia malayi hypothetical protein 0.0036 0.0032 0.0032
Trypanosoma cruzi metacaspase, putative 0.0044 0.0047 0.0079
Echinococcus multilocularis transient receptor potential cation channel 0.003 0.0021 0.0021
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0023 0.0007 0.0007
Schistosoma mansoni P2X receptor subunit 0.0286 0.0504 0.0504
Schistosoma mansoni amine GPCR 0.0702 0.1292 0.1292
Brugia malayi Trypsin-like protease protein 5 0.0023 0.0007 0.0007
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0028 0.0027
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0003 0.0001
Brugia malayi oxidoreductase 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0441 0.0799 0.0799
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0374 0.0672 0.0672
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.5307 1 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0066 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.003 0.0021 0.002
Plasmodium vivax phosphodiesterase gamma, putative 0.0031 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.1762 0.3296 0.3296
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0016
Echinococcus multilocularis tissue type plasminogen activator 0.0082 0.012 0.012
Brugia malayi Doublecortin family protein 0.0019 0.0001 0.0001
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0031 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Echinococcus granulosus cpg binding protein 0.0126 0.0203 0.0203
Trichomonas vaginalis esterase, putative 0.0218 0.0377 0.3734
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Plasmodium falciparum 1-cys peroxiredoxin 0.0084 0.0123 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0028 0.0028
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.008 0.008
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0112 0.0177 0.0177
Mycobacterium tuberculosis Probable oxidoreductase 0.0051 0.006 0.0058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0001 0.0002
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.003 0.0021 0.0036
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0023 0.0007 0.0007
Plasmodium vivax glutathione reductase, putative 0.0291 0.0515 0.0877
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0008 0.0077
Brugia malayi thymidylate synthase 0.0996 0.1847 0.1847
Schistosoma mansoni synaptojanin 0.002 0.0001 0.0001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0023 0.0007 0.0007
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0081 0.0118 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Schistosoma mansoni sulfide quinone reductase 0.0027 0.0015 0.0015
Plasmodium vivax exodeoxyribonuclease III, putative 0.002 0.0001 0.0001
Loa Loa (eye worm) oxidoreductase 0.003 0.0021 0.0021
Echinococcus granulosus WW domain containing oxidoreductase 0.003 0.0021 0.0021
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.003 0.0021 0.0019
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0003 0.0001
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0169 0.0284 0.0483
Brugia malayi N-terminal motif family protein 0.0134 0.0217 0.0217
Schistosoma mansoni cytochrome P450 0.003 0.0021 0.0021
Schistosoma mansoni short-chain dehydrogenase/reductase 0.003 0.0021 0.0021
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0209 0.0356
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.003 0.0021 0.0021
Schistosoma mansoni jumonji domain containing protein 0.0145 0.0239 0.0239
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0035
Loa Loa (eye worm) glutaminase 0.0537 0.098 0.098
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.0008 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Brugia malayi Kringle domain containing protein 0.0082 0.012 0.012
Brugia malayi hypothetical protein 0.0019 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Mycobacterium tuberculosis Probable dehydrogenase 0.003 0.0021 0.0019
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0098 0.0149 0.0252
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0066 0.0111
Trichomonas vaginalis Phospholipase C precursor, putative 0.002 0.0001 0.0014
Onchocerca volvulus 0.0024 0.0009 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0218 0.0377 0.3734
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0031 0.0022 0.0022
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Mycobacterium tuberculosis Conserved protein 0.0218 0.0377 0.0376
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0008
Echinococcus granulosus sodium and chloride dependent glycine 0.0099 0.0152 0.0152
Giardia lamblia Pyruvate kinase 0.0034 0.0028 0.0367
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0036 0.0032 0.0173
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Echinococcus granulosus sex peptide receptor 0.0702 0.1292 0.1292
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.004 0.004 0.004
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.002 0.0001 0.002
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0036 0.0033 0.0033
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0098 0.0149 0.0254
Echinococcus granulosus folate receptor beta 0.0821 0.1516 0.1516
Brugia malayi Importin beta-1 subunit 0.0028 0.0018 0.0018
Schistosoma mansoni neutral sphingomyelinase 0.002 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Onchocerca volvulus 0.003 0.0021 0.0113
Echinococcus multilocularis serotonin receptor 0.0702 0.1292 0.1292
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0101 0.0155 0.0155
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0001 0.0001
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0027 0.0015 0.0013
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0008 0.0014
Brugia malayi nuclear hormone receptor family member odr-7 0.0036 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0249 0.0436 0.4314
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0038 0.0063
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0003 0.0001
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0101 0.0155 0.0155
Brugia malayi sulfakinin receptor protein 0.0702 0.1292 0.1292
Trypanosoma brucei unspecified product 0.0033 0.0026 0.0042
Echinococcus granulosus Nuclear hormone receptor HR96 0.0036 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0009 0.009
Echinococcus granulosus g protein coupled receptor 0.0702 0.1292 0.1292
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0023 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0055 0.0546
Chlamydia trachomatis pyruvate kinase 0.0034 0.0028 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0015 0.0025
Schistosoma mansoni nuclear receptor nhr-48 0.0036 0.0032 0.0032
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0169 0.0284 0.0484
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0099 0.0152 0.0152
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.002 0.0001 0.0001
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0031 0.0022 0.0022
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0099 0.0152 0.0258
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0036
Schistosoma mansoni carbonyl reductase 0.003 0.0021 0.0021
Echinococcus granulosus glutamate synthase 0.0027 0.0015 0.0015
Brugia malayi jmjC domain containing protein 0.0145 0.0239 0.0239
Mycobacterium ulcerans short chain dehydrogenase 0.003 0.0021 0.0019
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0023 0.0008 0.0014
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0047 0.0079
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.002 0.0001 0.0001
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0061 0.008 0.0135
Entamoeba histolytica recQ family helicase, putative 0.0048 0.0056 0.0757
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Loa Loa (eye worm) hypothetical protein 0.0147 0.0243 0.0243
Echinococcus multilocularis cysteine protease 0.0024 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0702 0.1292 0.1292
Plasmodium vivax thioredoxin reductase, putative 0.0291 0.0515 0.0877
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.003 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.004 0.004 0.004
Echinococcus multilocularis musashi 0.0054 0.0066 0.0066
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0702 0.1292 0.1292
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0996 0.1847 0.1846
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0016 0.0016
Onchocerca volvulus Protein cycle homolog 0.0036 0.0033 0.0176
Plasmodium falciparum V-type H(+)-translocating pyrophosphatase, putative 0.0331 0.0589 0.1004
Toxoplasma gondii ImpB/MucB/SamB family protein 0.004 0.0039 0.0067
Echinococcus granulosus neuropeptides capa receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis retinol dehydrogenase 13 0.003 0.0021 0.0021
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0112 0.0177 0.0177
Toxoplasma gondii thioredoxin reductase 0.0291 0.0515 0.0878
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0101 0.0155 0.0153
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.003 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0021 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0022 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0702 0.1292 0.1292
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0099 0.0152 0.0152
Schistosoma mansoni dihydrofolate reductase 0.5307 1 1
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0079 0.0114 0.0113
Brugia malayi nuclear hormone receptor 0.0076 0.0108 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0012
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0027 0.0015 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0076 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0218 0.0377 0.0377
Schistosoma mansoni DNA helicase recq1 0.0037 0.0035 0.0035
Giardia lamblia Sgs1 DNA helicase, putative 0.0037 0.0035 0.0455
Entamoeba histolytica sphingomyelinase C precursor, putative 0.002 0.0001 0.002
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0584 0.1068 0.1068
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0031 0.0022 0.0036
Echinococcus multilocularis dihydrofolate reductase 0.5307 1 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0044 0.0044
Plasmodium falciparum glutathione reductase 0.0291 0.0515 0.0877
Brugia malayi G protein-coupled receptor 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0036 0.0032 0.0173
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0038 0.0377
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0407 0.0734 0.7271
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0027 0.0015 0.0015
Mycobacterium ulcerans putative regulatory protein 0.0079 0.0114 0.0113
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0264 0.0464 0.0462
Trypanosoma cruzi metacaspase, putative 0.0044 0.0047 0.0079
Trypanosoma brucei C-8 sterol isomerase, putative 0.0374 0.0672 0.1144
Loa Loa (eye worm) cytochrome P450 0.003 0.0021 0.0021
Echinococcus granulosus retinol dehydrogenase 11 0.003 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0032
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0044 0.0432
Loa Loa (eye worm) hypothetical protein 0.0067 0.0091 0.0091
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.003 0.0021 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0009 0.009
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Loa Loa (eye worm) programmed cell death 8 0.0027 0.0015 0.0015
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0027 0.0015 0.0182
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0027 0.0015 0.0024
Schistosoma mansoni short chain dehydrogenase 0.003 0.0021 0.0021
Schistosoma mansoni neuropeptide F-like receptor 0.0702 0.1292 0.1292
Echinococcus granulosus steroid dehydrogenase 0.003 0.0021 0.0021
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.003 0.0021 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Brugia malayi Nuclear hormone receptor E75 0.0036 0.0032 0.0032
Echinococcus multilocularis tar DNA binding protein 0.0188 0.032 0.032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0112 0.0177 0.0177
Brugia malayi hypothetical protein 0.003 0.0021 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.0076 0.0108 0.0108
Plasmodium falciparum amino acid transporter, putative 0.0099 0.0152 0.0257
Plasmodium vivax metacaspase 1, putative 0.0044 0.0047 0.0078
Loa Loa (eye worm) hypothetical protein 0.0218 0.0377 0.0377
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0076 0.0108 0.0108
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0038 0.0062
Onchocerca volvulus Protein ultraspiracle homolog 0.0076 0.0108 0.0584
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0076 0.0108 0.0108
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0047 0.0461
Loa Loa (eye worm) hypothetical protein 0.0036 0.0033 0.0033
Mycobacterium ulcerans dehydrogenase 0.003 0.0021 0.0019
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0036 0.0032 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0066 0.0658
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0111 0.0175 0.0175
Echinococcus granulosus cathepsin L cysteine proteinase 0.0024 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.003 0.0021 0.002
Echinococcus granulosus regulator of G protein signaling 7 0.0025 0.0012 0.0012
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0405 0.0405
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0222 0.0383 0.0654
Leishmania major fk506-binding protein 1-like protein 0.0169 0.0284 0.0484
Onchocerca volvulus 0.0702 0.1292 0.6993
Schistosoma mansoni organic anion transporter 0.0027 0.0016 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.003 0.0021 0.002
Loa Loa (eye worm) solute carrier family 6 member 4 0.0584 0.1068 0.1068
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0021
Brugia malayi RE15519p 0.0702 0.1292 0.1292
Echinococcus granulosus cathepsin l1 0.0024 0.0009 0.0009
Schistosoma mansoni glutaminase 0.0537 0.098 0.098
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Onchocerca volvulus 0.0019 0.0001 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Echinococcus multilocularis p2X purinoceptor 4 0.0286 0.0504 0.0504
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0009 0.0015
Schistosoma mansoni hypothetical protein 0.1525 0.2849 0.2849
Brugia malayi hypothetical protein 0.0036 0.0032 0.0032
Schistosoma mansoni fk506 binding protein 0.0023 0.0008 0.0008
Echinococcus multilocularis G protein coupled receptor 139 0.0702 0.1292 0.1292
Echinococcus granulosus serotonin receptor 0.0702 0.1292 0.1292
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0218 0.0377 0.0377
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0702 0.1292 0.1292
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0036 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0584 0.1068 0.1068
Echinococcus multilocularis glutamate synthase 0.0027 0.0015 0.0015
Echinococcus granulosus cathepsin l cysteine peptidase 0.0024 0.0009 0.0009
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0173 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0091 0.0135 0.0229
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0098 0.0149 0.0149
Brugia malayi Cathepsin L-like precursor 0.0024 0.0009 0.0009
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0054 0.0054
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.006 0.0058
Brugia malayi hypothetical protein 0.0437 0.079 0.079
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0003 0.0001
Schistosoma mansoni organic anion transporter 0.0027 0.0016 0.0016
Echinococcus granulosus Tolloid protein 1 0.0027 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0099 0.0151 0.0151
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0076 0.0108 0.0108
Schistosoma mansoni cercarial elastase (S01 family) 0.0023 0.0007 0.0007
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.141 0.2631 0.2631
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Entamoeba histolytica thioredoxin reductase, putative 0.0027 0.0015 0.0202
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 2, putative 0.0331 0.0589 0.1003
Loa Loa (eye worm) hypothetical protein 0.0112 0.0177 0.0177
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 1 0.0331 0.0589 0.1003
Onchocerca volvulus 0.003 0.0021 0.0113
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0054 0.009
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0009 0.0121
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.003 0.0021 0.0019
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0016 0.0016
Trypanosoma brucei short-chain dehydrogenase, putative 0.003 0.0021 0.0033
Schistosoma mansoni zinc finger protein 0.0036 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0047 0.0461
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0009 0.0049
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0056 0.0056
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0066 0.0113
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0016 0.0087
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0091 0.0091
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0151 0.0151
Mycobacterium ulcerans glutaminase 0.0537 0.098 0.0978
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.003 0.0021 0.002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0098 0.0149 0.2012
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0024 0.0009 0.009
Trypanosoma cruzi trypanothione reductase, putative 0.0291 0.0515 0.0878
Echinococcus granulosus fmrfamide receptor 0.0702 0.1292 0.1292
Echinococcus multilocularis Mastin 0.0023 0.0007 0.0007
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0027 0.0015 0.0023
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0013 0.0013
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0098 0.0149 0.0147
Plasmodium falciparum pyruvate kinase 0.0034 0.0028 0.0047
Schistosoma mansoni hypothetical protein 0.0112 0.0177 0.0177
Echinococcus granulosus somatostatin receptor 0.0702 0.1292 0.1292
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0047 0.0079
Trichomonas vaginalis short-chain dehydrogenase, putative 0.003 0.0021 0.0206
Mycobacterium tuberculosis Probable thiol peroxidase Tpx 0.0021 0.0005 0.0003
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0037 0.0035 0.0035
Trypanosoma cruzi cysteine peptidase, putative 0.0091 0.0135 0.0231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0101 0.0155 0.0264
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0029 0.005
Schistosoma mansoni amine GPCR 0.0702 0.1292 0.1292
Trypanosoma cruzi DNA polymerase kappa, putative 0.0074 0.0103 0.0176
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0054 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0066 0.0658
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0056 0.0056
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0027 0.0015 0.0025
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0702 0.1292 0.1292
Brugia malayi hypothetical protein 0.0702 0.1292 0.1292
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0024 0.0009 0.009
Onchocerca volvulus 0.0024 0.0009 0.0049
Brugia malayi MH2 domain containing protein 0.0249 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0058
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0016 0.0016
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.002 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0147 0.1456
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.003 0.0021 0.0019
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0031 0.0022 0.0036
Leishmania major hypothetical protein, conserved 0.003 0.0021 0.0035
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0197 0.0336 0.0572
Echinococcus granulosus cytochrome P450 2K1 0.003 0.0021 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.003 0.0021 0.0019
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0016 0.0016
Loa Loa (eye worm) dehydrogenase 0.003 0.0021 0.0021
Schistosoma mansoni glutamate synthase 0.0027 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0099 0.0152 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.0145 0.0239 0.0239
Brugia malayi Fibulin-1 precursor 0.0027 0.0014 0.0014
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.008 0.008
Trichomonas vaginalis glutaminase, putative 0.0537 0.098 0.9702
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0099 0.0152 0.0152
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0996 0.1847 0.1846
Plasmodium falciparum importin beta, putative 0.0028 0.0018 0.0029
Brugia malayi Pre-SET motif family protein 0.0061 0.008 0.008
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0702 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0702 0.1292 0.1292
Trypanosoma brucei polo-like protein kinase 0.0097 0.0147 0.0249
Echinococcus granulosus p2X purinoceptor 4 0.0286 0.0504 0.0504
Brugia malayi orphan nuclear receptor NR2E1 0.0036 0.0032 0.0032
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0441 0.0799 0.0799
Brugia malayi glutamate synthase 0.0027 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0101 0.0155 0.21
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0076 0.0108 0.0108
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0204 0.0204
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.003 0.0021 0.002
Schistosoma mansoni phd/f-box containing protein 0.0145 0.0239 0.0239
Onchocerca volvulus 0.0027 0.0015 0.008
Schistosoma mansoni ap endonuclease 0.0098 0.0149 0.0149
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0027 0.0015 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0042 0.0068
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0031 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0103 0.0174
Trichomonas vaginalis DNA helicase recq, putative 0.0048 0.0056 0.0551
Brugia malayi Nuclear hormone receptor E75 0.0036 0.0032 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0024 0.0024
Echinococcus multilocularis pyruvate kinase 0.0034 0.0028 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0055 0.0546
Onchocerca volvulus 0.0023 0.0007 0.0037
Schistosoma mansoni cpg binding protein 0.0126 0.0203 0.0203
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0702 0.1292 0.1292
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.002
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0403 0.0726 0.0723
Loa Loa (eye worm) TYRA-2 protein 0.0702 0.1292 0.1292
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0056 0.0096
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0702 0.1292 0.1292
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0155 0.0155
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0001 0.0001
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Probable conserved lipoprotein DsbF 0.0021 0.0005 0.0003
Plasmodium vivax V-type H(+)-translocating pyrophosphatase, putative 0.0331 0.0589 0.1004
Schistosoma mansoni hypothetical protein 0.0041 0.0041 0.0041
Trypanosoma brucei metacaspase MCA2 0.0044 0.0047 0.0077
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0037 0.0485
Schistosoma mansoni steroid hormone receptor ad4bp 0.0076 0.0108 0.0108
Trypanosoma cruzi PAB1-binding protein , putative 0.0126 0.0202 0.0344
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.003 0.0021 0.0019
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0654 0.12 0.1199
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0021 0.0035
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0074 0.0103 0.1024
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0249 0.0436 0.4314
Schistosoma mansoni caspase-7 (C14 family) 0.0115 0.0182 0.0182
Echinococcus multilocularis caspase 3 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.012 0.0191 0.0191
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0169 0.0284 0.0282

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.73 nM Inhibition of [3H]- WIN 35,428 binding to the dopamine transporter in rat striata. ChEMBL. 8831768
IC50 (binding) = 1.73 nM Inhibition of [3H]- WIN 35,428 binding to the dopamine transporter in rat striata. ChEMBL. 8831768
IC50 (binding) = 2.25 nM Inhibition of [3H]-paroxetine binding to serotonin transporter in rat frontal cortex ChEMBL. 8831768
IC50 (binding) = 2.25 nM Inhibition of [3H]-paroxetine binding to serotonin transporter in rat frontal cortex ChEMBL. 8831768
IC50 (binding) = 14.9 nM Inhibition of [3H]-nisoxatine binding to the norepinephrine transporter in rat midbrain. ChEMBL. 8831768
IC50 (binding) = 14.9 nM Inhibition of [3H]-nisoxatine binding to the norepinephrine transporter in rat midbrain. ChEMBL. 8831768
Ratio (binding) = 0.77 Selectivity for dopamine and serotonin transporters ChEMBL. 8831768
Ratio (binding) = 6.6 Selectivity for norpinephrine and serotonin transporters ChEMBL. 8831768

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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