Detailed view for Tb927.1.1000

Basic information

TDR Targets ID: 14564
Trypanosoma brucei, developmentally regulated phosphoprotein
Source Database / ID:  TriTrypDB  GeneDB

pI: 6.4926 | Length (AA): 420 | MW (Da): 47207 | Paralog Number: 0

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG5

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF02518   Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PF10436   Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

Gene Ontology

Mouse over links to read term descriptions.
GO:0005524   ATP binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 3 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
45 419 2e0a (A) 20 365 26.00 0 1 1.12076 -0.49
52 419 2e0a (A) 30 365 31.00 0 1 1.06399 0.05
243 339 1vjl (A) 19 131 32.00 0.57 0.41 0.363752 0.51

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

Upregulation Percent Ranking Stage Dataset
Upper 80-100% percentile Procyclic, Bloodstream Form. Siegel TN
Show/Hide expression data references
  • Siegel TN Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites.

Orthologs

Ortholog group members (OG5_127409)

Species Accession Gene Product
Arabidopsis thaliana AT3G06483   pyruvate dehydrogenase kinase
Brugia malayi Bm1_30205   kinase, mitochondrial precursor
Candida albicans CaO19.7281   similar to S. pombe SPAC644.11c predicted pyruvate dehydrogenase kinase
Caenorhabditis elegans CELE_ZK370.5   Protein PDHK-2
Drosophila melanogaster Dmel_CG8808   Pyruvate dehydrogenase kinase
Echinococcus granulosus EgrG_000147400   Pyruvate dehydrogenase lipoamide kinase
Echinococcus multilocularis EmuJ_000147400   Pyruvate dehydrogenase (lipoamide) kinase
Echinococcus multilocularis EmuJ_000136800   Pyruvate dehydrogenase (lipoamide) kinase
Homo sapiens ENSG00000004799   pyruvate dehydrogenase kinase, isozyme 4
Homo sapiens ENSG00000067992   pyruvate dehydrogenase kinase, isozyme 3
Homo sapiens 5163   pyruvate dehydrogenase kinase, isozyme 1
Homo sapiens ENSG00000005882   pyruvate dehydrogenase kinase, isozyme 2
Leishmania braziliensis LbrM.20.4500   developmentally regulated phosphoprotein-like protein
Leishmania donovani LdBPK_200310.1   developmentally regulated phosphoprotein-like protein
Leishmania infantum LinJ.20.0310   developmentally regulated phosphoprotein-like protein
Leishmania major LmjF.20.0280   developmentally regulated phosphoprotein-like protein
Leishmania mexicana LmxM.20.0280   developmentally regulated phosphoprotein-like protein
Loa Loa (eye worm) LOAG_02700   hypothetical protein
Mus musculus ENSMUSG00000035232   pyruvate dehydrogenase kinase, isoenzyme 3
Mus musculus ENSMUSG00000019577   pyruvate dehydrogenase kinase, isoenzyme 4
Mus musculus ENSMUSG00000006494   pyruvate dehydrogenase kinase, isoenzyme 1
Mus musculus ENSMUSG00000038967   pyruvate dehydrogenase kinase, isoenzyme 2
Oryza sativa 4344039   Os07g0637300
Oryza sativa 4332932   Os03g0370000
Schistosoma japonicum Sjp_0206730   ko:K00898 pyruvate dehydrogenase kinase [EC2.7.11.2], putative
Schistosoma japonicum Sjp_0215760   [Pyruvate dehydrogenase [lipoamide]] kinase, mitochondrial precursor, putative
Schistosoma mansoni Smp_068170.1   pyruvate dehydrogenase
Schistosoma mansoni Smp_068170.2   pyruvate dehydrogenase
Schistosoma mansoni Smp_140580   pyruvate dehydrogenase
Schmidtea mediterranea mk4.003066.04  
Schmidtea mediterranea mk4.003066.06   Probable
Schmidtea mediterranea mk4.004229.02  
Schmidtea mediterranea mk4.003066.05  
Schmidtea mediterranea mk4.004229.01  
Trypanosoma brucei gambiense Tbg972.1.380   developmentally regulated phosphoprotein
Trypanosoma brucei Tb927.1.1000   developmentally regulated phosphoprotein
Trypanosoma congolense TcIL3000_1_420   developmentally regulated phosphoprotein, putative
Trypanosoma cruzi TcCLB.511421.110   developmentally regulated phosphoprotein, putative

Essentiality

Tb927.1.1000 has direct evidence of essentiality
Gene/Ortholog Organism Phenotype Source Study
Tb927.1.1000 this record Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb927.1.1000 this record Trypanosoma brucei significant loss of fitness in bloodstream forms (6 days) alsford
Tb927.1.1000 this record Trypanosoma brucei significant loss of fitness in procyclic forms alsford
Tb927.1.1000 this record Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
Show/Hide essentiality data references
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.

Phenotypes and Validation (curated)

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Drugs/Inhibitors
growth (GO:0040007) normal (PATO:0000461) single cell organism (CARO:0000064) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
cell morphogenesis (GO:0000902) normal (PATO:0000461) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
regulation of cell motility (GO:0051270) normal (PATO:0000461) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
cell cycle (GO:0007049) normal (PATO:0000461) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
mitochondrion organization and biogenesis (GO:0007005) normal (PATO:0000461) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
regulation of cell motility (GO:0051270) normal (PATO:0000461) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
endocytosis (GO:0006897) normal (PATO:0000461) bloodstream stage (PLO:0040) inferred from RNAi experiment (ECO:0000019) Trypanosoma brucei brucei No drug identifiers listed for this gene.
Annotator: ts4@sanger.ac.uk. Comment: . References: 16963636
cell proliferation (GO:0008283) normal (PATO:0000461) bloodstream stage trypomastigotes (PLO:0027) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in bloodstream forms (stage 3 days). References: 21363968
cell proliferation (GO:0008283) decreased (PATO:0000468) bloodstream stage trypomastigotes (PLO:0027) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: decreased cell proliferation (significant loss of fitness) in bloodstream forms (stage 6 days). References: 21363968
cell proliferation (GO:0008283) decreased (PATO:0000468) procyclic (PLO:0034) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: decreased cell proliferation (significant loss of fitness) in procyclic forms . References: 21363968
cell proliferation (GO:0008283) normal (PATO:0000461) procyclic (PLO:0034) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in differentiation of procyclic to bloodstream forms . References: 21363968

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Druggability index (range: 0 to 1): 0.6

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Homo sapiens pyruvate dehydrogenase kinase, isozyme 1 Compounds References
Homo sapiens pyruvate dehydrogenase kinase, isozyme 4 Compounds References
Rattus norvegicus Pyruvate dehydrogenase kinase Compounds References
Homo sapiens pyruvate dehydrogenase kinase, isozyme 2 Compounds References
Homo sapiens pyruvate dehydrogenase kinase, isozyme 3 Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.0144 1 0.5
0.1119 1 0.5
0.0144 1 0.5
0.0509 1 1
0.4538 1 1
0.035 0.6999 1
0.2393 1 1
0.1834 1 1
0.5321 1 1
0.2485 1 1
0.1046 0.9313 0.9313
0.0144 1 0.5
0.2349 1 1
0.0611 0.6106 1
0.2061 1 0.5
0.1105 1 1
0.0144 1 0.5
0.7864 1 1
0.0144 1 0.5
0.0481 1 1
0.0575 1 0.5
0.0366 1 1
0.2462 1 0.5
0.0469 0.2902 1
0.328 0.5066 0.9181
0.3556 0.3188 1
0.2435 0.7911 0.5
0.4647 0.6159 1
0.0144 1 0.5
0.0144 0.3918 0.3698
0.0745 1 1
0.0649 1 1
0.0575 1 0.5
0.4896 1 1
0.0447 1 1
0.1515 1 1
0.2973 1 0.5
0.0144 0.2669 0.7062
0.6703 1 1
0.184 0.6424 1
0.3434 1 1
0.0558 1 1
0.2713 0.2533 0.308
0.0144 1 0.5
0.0504 0.252 0.6838
0.9958 1 1
1.1384 1 1
0.1152 1 1
0.2491 0.9218 1
0.3656 1 1
0.4538 1 1
0.0144 1 0.5
0.089 0.656 1
0.0649 1 1
0.0384 0.5974 1
0.552 1 0.5
0.0511 1 1
0.1976 1 1
0.1274 1 1
1.141 1 1
0.1234 1 1
0.554 1 1
0.2266 1 1
0.4879 0.384 1
3.0139 0.29 0.7563
0.0477 1 1
0.0156 0.3002 1
0.0144 1 0.5
0.0123 0.2977 0.5
0.0501 1 1
0.1712 1 1
0.012 0.2506 1
0.197 1 1
0.2439 0.2619 1
0.9953 1 0.5
0.0128 0.3049 1
0.9478 1 1
0.0649 1 1
0.0695 0.3203 1
0.6262 1 1
0.0375 1 0.5
0.0375 0.6697 1
0.2565 1 1
0.0144 1 0.5
0.482 1 1
0.0747 1 1
0.0371 0.3457 0.5
0.2483 1 1
0.4245 1 0.5
0.5704 1 1
0.516 1 1
0.155 1 1
0.184 0.6424 1
0.0741 1 0.5
0.2839 1 0.5
1.141 1 1
0.3103 1 1
0.1304 1 1
0.2713 0.2533 0.308
0.4896 1 1
0.6509 1 1
0.6653 1 1
0.5071 0.3648 1
0.1985 0.6963 1
3.105 0.7133 1
0.0144 1 0.5
0.4881 1 1
0.0667 1 1
0.5395 1 1
0.0545 0.3929 1
0.2569 0.6165 1
0.5321 1 1
0.0837 0.5215 1
0.0144 1 0.5
0.0144 0.7314 0
0.2955 0.9545 0.5
0.0869 0.2833 1
0.3691 0.3254 0.5
0.2895 0.252 0.2943
0.0144 1 0.5
0.098 1 1
0.3357 1 0.5
0.0484 0.7656 1
0.7157 1 0.5
0.1523 0.5544 1
0.2887 0.2527 0.308
0.0266 0.5886 1
1.0858 1 1
0.5071 0.3648 1
0.6144 1 1
0.2809 1 1
0.5279 1 0.5
0.0144 0.9883 1
0.7581 1 1
0.1036 1 1
0.0946 1 1
0.0126 0.7176 1
0.0144 1 0.5
0.328 0.5066 0.9181
0.014 0.741 1
0.0575 1 0.5
0.1481 1 1
0.0202 0.273 0.4809
0.0799 0.5718 1
0.9573 1 0.5
0.328 0.5066 0.9181
0.0543 0.6375 1
0.0341 0.2623 0.6553
0.8767 1 1
0.714 1 1
0.4538 1 1
0.0194 0.3249 0.325
0.0144 1 0.5
0.2494 1 1
0.2531 0.5427 1
0.1508 1 1
0.4297 1 1
0.182 0.2526 0.3074
0.202 0.5902 1
0.194 1 1
0.0527 1 1
0.2252 1 1
0.565 1 1
0.2455 0.7693 1
0.028 0.6352 0.5
0.197 1 1
0.116 1 1
0.3305 1 1
1.141 1 1
0.0116 0.5818 0.5
0.0144 0.7562 1
0.1926 1 1
0.0522 1 0.5
0.0481189 1 0.5
0.5302 1 1
0.0677 1 1
0.1215 1 1
0.1206 1 1
0.1485 1 1
3.3351 0.515 0.5882
0.3151 1 1
0.0543 0.2724 0.2722
0.3421 1 1
0.0144 1 0.5
0.0465 0.559 1
0.172 1 1
0.2809 1 1
0.1963 1 1
0.0105 0.2546 0.3008
0.2955 0.9545 0.5
0.3892 0.2813 1
0.0144 0.3043 1
0.0144 1 0.5
0.0528 0.2528 0.6426
0.6305 1 1
0.7585 1 1
0.1337 0.43 1
0.064 1 0.5
0.0251 0.2736 0.6606
0.2422 1 1
0.0144 1 0.5
0.2908 1 1
0.4076 1 1
0.0502 1 1
0.0144 1 0.5
0.6144 1 1
0.0144 1 0.5
0.3347 1 1
0.5569 1 1
0.2418 1 1
0.0144 1 0.5
1.9365 0.3516 1
0.026 1 1
0.0866 1 1
0.3994 1 1
0.0496 0.2893 1
0.6144 1 1
0.0152 1 1
0.5043 1 0.5
0.1356 1 1
0.5566 1 1
0.6487 1 1
0.0105 0.2546 0.3008
0.1887 0.3676 1
0.0201 0.2916 1
0.0212 1 1
0.0118 0.393 1
0.4369 1 1
0.0477 0.3076 1
0.1134 1 1
0.184 0.6424 1
0.0447 1 1
0.173 1 1
0.0591 1 1
0.1407 1 1
0.2175 1 1
0.2062 1 1
0.2076 1 1
0.4425 1 0.5
0.0653 0.591 1
0.1753 0.96 1
0.3019 1 1
0.5317 1 1
0.0144 1 0.5
0.202 0.5902 1
0.1691 1 1
0.4677 1 1
0.2828 1 1
0.0243 0.5974 1
0.2373 1 1
0.1528 1 1
0.4647 0.6159 1
0.202 0.5902 1
0.4752 1 0.5
0.1478 1 1
0.0481 1 1
0.016 0.5212 1
0.2982 0.2519 0.3067
0.0262 0.8095 1
0.0144 1 0.5
0.0643 0.6497 1
0.0273 1 1
0.3566 1 1
0.0144 1 0.5
0.0144 1 0.5
0.0636 0.6611 1
0.0144 0.5169 1
0.0496 0.2893 1
0.328 0.5066 0.9181
0.1545 1 1
0.1036 1 1
0.5691 1 1
0.5289 1 0.5
0.058 0.3704 1
0.0545 1 1
0.2688 0.9238 1
0.0614 0.6508 1
0.5758 1 0.5
0.149 1 1
0.4328 1 1
4.7154 1 1
0.7567 1 1
0.1215 1 1
0.2017 1 1
0.0928 1 1
0.0144 0.3105 0.2939
0.0144 1 0.5
0.3892 0.2813 1
0.0475 1 1
0.1665 1 1
0.0236 0.2921 1
0.0733 1 1
0.2687 1 1
0.0144 1 0.5
0.4082 1 1
0.0144 1 0.5
0.0144 1 0.5
0.0466 0.6688 1
0.0447 1 1
0.0144 1 0.5
0.5668 1 1
0.0144 1 1
0.0144 0.55 1
0.046 0.4588 1
0.7567 1 1
0.0732 1 1
0.0144 1 0.5
0.0554 0.2611 0.6629
0.0144 1 0.5
0.5359 1 0.5
0.1822 1 1
0.0287 1 0.5
0.2744 0.2527 0.3078
0.4586 1 1
0.2982 0.2519 0.3067
0.0144 1 0.5
0.1004 1 1
0.7694 1 0.5
0.0144 1 0.5
0.0144 1 0.5
0.3151 1 1
0.0507 0.7437 1
0.1607 1 1
0.0495 1 1
0.7582 1 0.5
0.6367 1 0.5
0.0144 1 0.5
0.2979 1 0.5
0.2074 1 1
0.0207 0.3273 0.3295
0.328 0.5066 0.9181
0.0727 1 1
0.0819 0.4926 1
0.0144 1 0.5
0.3305 1 1
0.0369 1 1
0.1835 1 0.5
0.0144 1 0.5
0.0269 1 1
0.3393 1 1
0.0969 1 0.5
0.5541 1 1
0.0618 1 1
0.5131 0.4566 1
0.0486 0.2987 1
0.1337 0.43 1
0.5839 1 1
0.1761 1 1
0.1046 0.9313 0.9313
0.0279 1 1
0.0144 1 0.5
0.134 1 1
0.1938 0.5408 1
0.4814 1 0.5
0.0522 0.4413 1
0.025 1 1
0.3556 0.3188 1
0.023 0.2742 1
0.1677 1 1
0.5592 1 0.5
0.0575 1 0.5
0.0144 1 0.5
0.7567 1 1
0.5597 1 1
0.0413 0.2744 1
0.2062 1 1
0.1571 1 1
0.0618 0.8385 1
0.6296 1 1
0.016 0.378 1
0.1864 1 1
0.0144 0.3521 1
0.2631 1 1
0.0144 1 0.5
0.0123 0.3087 1
0.254 1 1
0.0472 1 1
0.0144 1 0.5
0.3892 0.2813 1
0.3474 1 1
0.0937 1 0.5
0.0144 1 0.5
0.1114 0.604 1
0.4391 1 1
0.087 1 1
0.0522 0.5783 1
0.0144 1 0.5
0.2484 1 1
0.2073 1 1
0.0536 1 1
0.0613 0.6577 1
0.0144 1 0.5
0.0734 1 1
0.1685 1 1
0.0495 1 1
0.0126 0.7176 1
0.0787 1 1
0.1761 1 1
0.0469 0.662 1
0.016 1 1
0.376 1 1
0.1695 1 1
0.3039 1 1
0.0144 1 1
0.0383 0.6244 1
0.2448 1 1
0.0486 0.3172 0.3108
0.0819 0.4926 1
0.2762 1 0.5
0.7476 0.3049 1
0.427 1 1
0.0575 1 0.5
0.0194 0.3624 1
0.2544 1 1
0.0491 0.7206 1
0.016 1 1
0.1539 0.6274 1
0.3629 1 1
0.1716 1 1
0.0636 1 1
0.2326 0.4489 1
0.0144 1 0.5
0.1564 1 1
0.0925 1 1
0.0144 1 0.5
0.2744 0.2527 0.3078
0.0144 1 0.5
0.3924 1 1
0.4671 1 0.5
0.0194 0.3249 0.325
0.5566 1 1
0.0144 1 0.5
0.1305 1 0.5
0.0384 0.3391 1
0.1793 0.5356 1
0.2518 1 0.5
0.0626 0.7865 1
0.0144 0.5408 0.5
0.049 1 1
0.6168 1 1
0.0634 0.2516 1
0.1922 1 1
0.0472 0.314 1
0.1071 1 1
0.6113 0.3464 1
0.1407 1 1
0.5321 1 1
1.989 0.6134 1
0.202 0.5902 1
0.0537 0.3174 0.1443
0.1157 1 1
1.1384 1 1
0.2475 1 1
0.0144 1 0.5
0.9012 1 0.5
0.79 1 1
0.0144 0.5925 1
0.0144 1 0.5
0.1268 1 1
0.2678 1 1
0.5752 1 0.5
0.0144 1 0.5
0.2973 0.2501 0.3034
0.2122 1 1
0.5297 0.8075 0.8577
0.0481 0.5717 1
0.7567 1 1
0.0232 0.3769 0.7821
0.1714 1 1
0.014 0.3941 0.7568
4.7183 1 1
0.2413 1 1
0.5071 0.3648 1
0.1679 1 1
1.086 1 1
0.2982 0.2519 0.3067
0.1157 1 1
0.1694 1 1
0.0356 0.3593 1
0.0144 1 0.5
0.0144 1 0.5
0.4209 1 1
0.0144 1 0.5
0.4444 1 1
0.0144 1 0.5
0.0152 0.4592 0.4592
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0.0359 0.7756 1
0.0759 0.567 1
0.1429 1 0.5
0.1232 1 1
0.4651 1 1
0.2008 1 1
0.0354 1 1
0.1849 1 0.5
0.2955 0.9545 0.5
0.2713 0.2533 0.308
0.5706 1 1
0.016 1 1
0.0616 1 1
0.5712 1 1
0.0144 1 0.5
0.0144 1 0.5
0.0481 1 1
1.0623 1 0.5
0.7996 1 1
0.0287 1 0.5
0.1559 1 1
0.0239 1 1
0.0515 0.9966 1
0.2522 1 1
0.046 0.9952 1
0.0237 0.7527 1
0.2571 1 0.5
0.0997 1 1
0.4209 1 1
0.0266 0.3613 0.3461
0.0602 1 0.5
0.0505881 1 0.5
0.173 1 1
0.0144 1 0.5
0.2336 1 1
0.0496 0.2893 1
0.1241 1 0.5
0.2531 0.5427 1
0.5728 1 1
0.0144 1 0.5
0.3627 1 1
0.3524 1 0.5
0.3485 1 1
0.1006 1 1
0.3831 1 1
0.1623 1 1
0.0946 1 1
0.202 0.5902 1
0.3474 1 1
0.0974 0.291 0.5533
0.3819 1 1
0.35 1 1
0.1127 0.4197 0.6072
0.0273 0.368 1
0.0736 0.8791 1
0.3084 1 0.5
0.0144 0.3475 1
0.3457 1 1
1.1151 1 1
0.5248 1 1
0.1089 0.7607 1
0.3388 1 1
0.0973 0.9936 1
0.3972 1 1
0.0959 1 1
0.9847 1 1
0.3818 1 1
0.2887 0.2527 0.308
0.2535 1 1
0.0144 1 0.5
0.0613 0.7292 1
0.0144 1 0.5
0.6946 1 1
0.0929 1 0.5
0.0742 1 0.5
0.5395 1 1
0.3979 1 1
0.0962 1 1
0.4833 1 1
0.0267 1 1
0.0481 1 1
0.0119 0.2913 1
0.9958 1 1
0.0887 0.4059 1
0.0117 0.3605 1
0.0355 0.6228 1
0.3089 1 1
0.7437 0.9621 1
0.427 1 1
0.5395 1 1
0.6296 1 1
0.1832 1 0.5
0.0575 0.7274 1
0.1737 1 1
0.2761 0.3067 0.3067
0.0777 1 1
0.016 1 1
0.3566 1 1
0.2744 0.2527 0.3078
0.1818 1 1
0.0504 1 1
0.4983 1 1
0.05 0.3095 0.3041
0.0561 0.4102 1
0.0733 1 1
0.2105 1 1
0.0272 0.3336 1
0.1113 1 1
0.1305 1 0.5
0.4647 0.6159 1
0.2425 0.6987 1
0.0512 0.7104 1
0.1429 1 0.5
0.0967 0.7657 1
0.0468 1 1
0.0734 1 0.5
0.3869 1 1
0.5704 1 1
0.0144 1 1
0.6262 1 1
0.1825 1 0.5
0.6974 1 0.5
0.035 0.6999 1
0.554 1 1
0.5395 1 1
0.1342 1 1
0.0479 1 1
0.2608 0.3193 0.3191
0.0501 0.3286 1
0.0118 0.2583 1
0.7582 1 0.5
0.2661 1 0.5
0.2439 0.2619 1
0.3305 1 1
0.5395 1 1
0.0144 1 0.5
0.3863 1 1
0.6168 1 1
0.0144 1 0.5
0.1014 1 0.5
0.0278 1 1
0.0391 0.5307 1
0.0446 1 1
0.0698 0.5316 1
0.0953 1 1
0.403 1 0.5
0.202 0.5902 1
0.0515 0.6307 1
0.0144 1 0.5
0.0337 0.3846 1
0.0144 1 0.5
0.0144 1 0.5
0.3149 1 1
0.0653 0.591 1
0.0144 0.3119 1
0.3079 1 1
0.1556 1 1
0.0144 1 0.5
0.4297 1 1
0.0144 1 0.5
0.3477 1 1
0.5706 1 1
0.3924 1 1
0.0229 0.3643 0.4228
0.0575 1 0.5
0.2688 0.9238 1
0.0378 0.3312 1
0.5664 1 1
0.1118 1 0.5
0.0981 1 0.5
0.016 1 1
0.0877 0.2725 1
0.5252 1 1
0.058 0.3704 1
0.0819 0.4926 1
0.162 1 1
0.0121 0.7128 1
0.0528 0.365 1
0.4043 0.268 1
0.0575 1 0.5
0.2419 1 1
0.0144 1 0.5
0.5297 0.8075 0.8577
0.6113 0.3464 1
0.0491 0.5293 1
0.0144 0.5598 0.5
0.5252 1 1
0.1495 1 1
0.0681 0.3599 0.5
0.4275 1 1
0.0115 0.2701 1
0.0144 1 0.5
0.2691 1 1
0.1046 0.9313 0.9313
0.2185 1 0.5
0.202 0.5902 1
0.0144 1 0.5
0.0249 0.2947 0.5768
0.5576 1 1
0.5071 0.3648 1
0.0144 1 0.5
0.4647 0.6159 1
0.033 0.328 1
0.2932 1 0.5
0.7665 1 0.5
0.014 0.741 1
0.1488 1 1
0.0653 0.591 1
0.2045 1 1
0.5248 1 1
0.1127 0.4197 0.6072
0.1086 0.4417 0.3668
0.4369 1 1
0.0144 0.7916 0
0.0626 0.3699 1
0.039 1 1
0.79 1 1
0.3892 0.2813 1
0.6807 1 1
0.5027 1 1
0.0375 0.6462 1
0.817 1 1
0.7567 1 1
0.1822 1 1
0.0254 0.3276 0.5
0.2114 0.3357 1
0.0295 0.3107 0.3107
0.5138 1 1
0.0144 1 0.5
0.1346 1 0.5
0.0116 0.2633 1
0.1328 1 1
0.0621 0.7901 1
0.0463 0.324 1
0.4188 1 0.5
0.1579 0.3157 1
0.115 1 0.5
0.1686 1 1
0.4843 0.518 1
0.7595 1 1
0.1688 1 1
0.254 1 1
0.0239 0.3751 1
0.0144 1 0.5
0.173 1 1
0.3916 1 1
0.0727 0.5012 1
0.0575 1 0.5
0.051 0.9479 1
0.0144 1 0.5
0.0285 0.8219 0.8219
0.3549 1 1
0.1138 1 0.5
0.0209 0.4357 1
0.714 1 1
0.2418 1 1
0.2026 1 1
0.1234 1 1
0.2685 1 0.5
0.0133 0.2662 1
1.0214 1 1
0.0884 1 1
0.1127 0.4197 0.6072
0.0373 1 1
0.0983 0.5003 1
0.0144 1 0.5
0.0102 0.5474 1
0.2047 1 0.5
0.3892 0.2813 1
0.0118 0.2666 1
0.5071 0.3648 1
0.4778 1 1
0.0634 0.2516 1
0.1539 0.6274 1
0.223 1 1
0.0144 1 0.5
0.7788 0.4871 1
0.1754 1 1
0.0144 1 0.5
0.2114 0.3357 1
0.5569 1 1
0.184 0.6424 1
0.1814 1 1
0.0144 1 1
0.4265 1 1
0.4896 1 0.5
0.3421 1 1
0.0541 0.6008 1
0.4594 1 0.5
0.2569 0.6165 1
0.1262 1 1
0.2491 0.9218 1
0.0144 1 0.5
0.4879 0.384 1
0.16 1 1
0.0666 0.8409 1
0.0513 0.7486 1
0.0734 1 1
0.8478 1 1
0.0144 1 0.5
0.0843 1 1
0.0373 1 1
0.0144 1 0.5
0.526 1 1
0.4043 0.268 1
0.0144 1 0.5
0.7545 0.6361 1
0.086 1 1
0.4305 1 1
0.4976 1 1
0.0543 0.2724 0.2722
0.099 0.3572 0.3554
0.4672 1 0.5
0.0631 0.507 1
0.1136 1 1
0.0144 1 0.5
0.206 1 0.5
0.1336 0.4689 1

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

1 literature reference was collected for this gene.

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Gene identifier Tb927.1.1000 (Trypanosoma brucei), developmentally regulated phosphoprotein
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