Detailed view for MUP045

Basic information

TDR Targets ID: 953021
Mycobacterium ulcerans, beta-ketoacyl synthase-like protein
Source Database / ID:  KEGG  

pI: 5.2906 | Length (AA): 328 | MW (Da): 34719 | Paralog Number: 2

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF08541   3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
PF08545   3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III

Gene Ontology

Mouse over links to read term descriptions.
GO:0004315   3-oxoacyl-[acyl-carrier-protein] synthase activity  
GO:0003824   catalytic activity  
GO:0008152   metabolic process  
GO:0006633   fatty acid biosynthetic process  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 4 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
1 320 3s3l (A) 1 342 34.00 0 1 1.32371 0.06
4 327 3lm6 (B) 13 327 17.00 0 1 1.049 0.37
5 324 4xs9 (A) 10 348 28.00 0 1 1.32281 -0.48
8 165 4z19 (A) 5 166 35.00 0.000000052 1 0.759807 0.46

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_129509)

Species Accession Gene Product
Arabidopsis thaliana AT1G62640   3-ketoacyl-acyl carrier protein synthase III
Chlamydia trachomatis CT_239   oxoacyl-ACP synthase III
Escherichia coli b1091   3-oxoacyl-[acyl-carrier-protein] synthase III
Mycobacterium tuberculosis Rv0533c   3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III)
Mycobacterium ulcerans MUL_3531   3-oxoacyl-ACP synthase
Mycobacterium ulcerans MUL_0632   3-oxoacyl-ACP synthase
Mycobacterium ulcerans MUP045   beta-ketoacyl synthase-like protein
Neospora caninum NCLIV_031900   3-oxoacyl-(acyl-carrier-protein) synthase III family protein, putative
Oryza sativa 4337178   Os04g0643300
Plasmodium berghei PBANKA_0308200   apicoplast beta-ketoacyl-acyl carrier protein synthase III precursor, putative
Plasmodium falciparum PF3D7_0211400   beta-ketoacyl-ACP synthase III
Plasmodium knowlesi PKNH_0409900   beta-ketoacyl-acyl carrier protein synthase III precursor, putative
Plasmodium vivax PVX_002960   beta-ketoacyl-acyl carrier protein synthase III precursor, putative
Schmidtea mediterranea mk4.058575.00  
Wolbachia endosymbiont of Brugia malayi Wbm0614   3-oxoacyl-ACP synthase

Essentiality

MUP045 has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
mtu541 Mycobacterium tuberculosis non-essential nmpdr
b1091 Escherichia coli essential goodall
PBANKA_0308200 Plasmodium berghei Slow plasmo
Show/Hide essentiality data references
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Escherichia coli 3-oxoacyl-[acyl-carrier-protein] synthase III Compounds References
Enterococcus faecalis (strain ATCC 700802 / V583) Beta-ketoacyl-ACP synthase III Compounds References
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) Beta-ketoacyl-ACP synthase III Compounds References
Pseudomonas aeruginosa 2-heptyl-4(1H)-quinolone synthase PqsD Compounds References
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) Beta-ketoacyl-ACP synthase III Compounds References
Plasmodium falciparum beta-ketoacyl-ACP synthase III Compounds References
Staphylococcus aureus subsp. aureus Mu50 Beta-ketoacyl-ACP synthase III Compounds References
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.0354 0.4517 1
0.2955 1 1
0.1259 0.3468 1
0.0718 0.3742 0.374
0.3745 1 0.5
0.4842 0.2981 0.5058
0.2286 0.5 0.5
0.7725 0.835 1
0.8226 1 1
0.0339834 1 0.5
0.0659 1 1
0.6062 1 1
0.0691 0.6027 1
0.4561 0.5932 1
0.3629 1 1
0.1332 1 1
0.4052 1 1
0.4842 0.2981 0.5058
0.075 0.5599 0.5599
0.0368 0.4788 1
0.0633 0.5066 0.4922
0.0383 1 0.5
0.2548 1 1
0.6062 1 1
0.0657 0.8547 1
0.8226 1 1
0.1614 0.6269 1
0.6515 0.5949 0.9007
0.0383 1 0.5
0.037 0.643 1
0.1574 0.2536 0.3257
0.0311 0.3012 1
0.0713 1 1
0.1656 0.2577 0.2574
0.0658 0.7949 1
0.1987 1 0.5
0.0306 0.3646 1
0.3811 0.4714 1
0.0726 0.5691 0.5691
0.3329 0.2526 1
0.0383 1 0.5
0.2309 1 1
0.6653 1 1
0.031 0.643 0.6322
0.0383 0.2936 0.2936
0.0354 0.4455 1
0.0383 0.3349 1
0.1263 0.6296 1
0.2205 1 1
0.1609 0.3543 0.3542
0.0675 1 1
0.0383 0.3335 0.5
0.0622 0.632 1
0.4584 0.4255 0.5845
0.0368 0.4788 1
0.2375 0.2916 1
0.072 1 1
0.0204 0.742 0.5
0.3398 1 1
0.0622 1 0.5
0.0312 0.3127 0.5908
0.0307 1 0.5
0.0974 0.2907 0.2968
0.4842 0.2981 0.5058
0.4842 0.2981 0.5058
0.0315482 0.326332 1
0.119 1 1
0.263 0.5924 0.8317
0.054 1 1
0.8226 1 1
0.6515 0.5949 0.9007
0.0634 0.3438 0.5
0.1322 0.5485 0.5461
0.0661 0.9118 1
0.1899 1 0.5
0.4584 0.4255 0.5845
0.0642 1 1
0.6403 1 0.5
0.064 0.5 0.5
0.0682 1 1
0.0648 1 0.5
0.0383 1 1
0.2285 1 0.5
0.4584 0.4255 0.5845
0.0683 1 1
0.2309 1 1
0.0383 0.3251 1
0.3887 0.8264 1
0.4842 0.2981 0.5058
0.068 0.3141 0.314
0.3982 1 1
0.036 0.4455 1
0.345 1 1
0.1919 1 1
0.0651 0.8934 1
0.0338 0.4629 1
0.0652 1 1
0.0654 0.7347 1
0.5644 0.8356 1
0.2495 0.4807 1
0.2304 0.4952 1
0.0679 0.3358 1
0.385 0.7967 1
0.0672 0.8949 1
0.4842 0.2981 0.5058
0.0663 0.3141 0.3141
0.263 0.5923 0.8317
0.7725 0.835 1
0.0383 1 1
0.1978 0.3218 1
0.0368 0.4788 1
0.4584 0.4255 0.5845
0.1275 0.2534 0.2787
0.0318 0.264 0.2594
0.0315 1 0.5
0.0323 0.3917 1
0.1899 1 0.5
0.0315 1 1
0.2232 1 0.5
0.2501 0.6346 0.5
0.0306 0.5984 1
0.0368 0.4788 1
0.5644 0.8356 1
0.032019 0.5 0.5
0.3719 0.4455 1
0.3281 1 0.5
0.0338 0.4629 1
0.075 0.5604 0.5599
0.0383 0.8715 0.5
0.0739 0.5517 0.5517
0.0308 0.4175 1
0.3787 0.5 0.5
0.1278 1 0.5
0.1261 0.2939 1
0.0674 0.7612 1
0.1719 0.4293 0.4639
0.031 0.8874 1
0.3257 0.5567 1
0.5644 0.8356 1
0.0624 0.2956 1
0.0623 1 1
0.5983 1 1
0.032 0.5317 0.5094
0.0973 1 0.5
0.3327 1 1
0.2324 1 1
0.072 0.7476 0.7476
0.0318 0.3952 1
0.1149 1 1
0.0974 0.2907 0.2968
0.0383 0.5395 1
0.0633 0.5066 0.4922
0.0628 1 1
0.0383 0.5 0.5
0.0383 1 0.5
0.3418 0.5 0.5
0.1606 0.6128 1
0.6515 0.5949 0.9007
0.0369 1 0.5
0.8226 1 1
0.0327 0.4994 0
0.0312 0.41 1
0.0656 1 1
0.263 0.8089 0.8318
0.2506 1 0.5
0.4842 0.2981 0.5058
0.3859 0.7153 0.5
0.0313 0.3081 1
1.0597 0.6539 1
0.1925 1 1
0.1283 0.8159 1
0.0655 1 1
0.2281 0.3989 1
0.0716 0.5597 0.5595
0.6365 1 0.5
0.2433 1 0.5
0.4842 0.2981 0.5058
0.1612 0.2801 0.2796
0.2089 1 0.5
0.4842 0.2981 0.5058
0.8226 1 1
0.031 1 0.5
0.3418 0.5 0.5
0.0658 0.7651 1
0.1514 0.3314 1
0.0309 0.7716 1
0.0383 0.4083 1
0.0726 0.5691 0.5691
0.3541 0.7678 1
0.1034 0.8295 1
0.068 1 0.5
0.0383 0.5 0.5
0.8226 1 1
0.4584 0.4255 0.5845
0.4858 1 0.5
0.2487 1 0.5
0.0684 0.8501 1
0.0383 0.8924 1
0.5854 1 0.5
0.6021 0.5 0.5
0.1961 1 0.5
0.0626 1 1
0.1079 1 1
0.1027 0.5586 0.5
0.0311 0.6539 1
0.0633 0.5066 0.4922
0.0512 0.5112 0.5
0.0376 1 0.5
0.7939 1 1
0.0766 0.3101 1
0.0684 1 0.5
0.0334 0.6484 1
0.0352 0.6669 1
0.5918 1 1
0.1312 0.5244 1
0.6515 0.5949 0.9007
0.263 0.5923 0.8317
0.0719 0.9127 1
0.6316 1 1
0.0229 0.5 0.5
0.031 0.3904 0.5054
0.0719 0.9127 1
0.2548 1 1
0.0629 0.9398 1
0.032019 0.5 0.5
0.0306 0.3621 1
1.1857 1 0.5
0.4749 1 1
0.0613 0.2994 0.2992
0.5644 0.8356 1
0.0638 0.4251 0.5117
0.0689 0.3248 0.3248
0.1612 0.2807 0.2801
0.5062 1 0.5
0.2649 1 0.5
0.0691 1 0.5
0.4584 0.4255 0.5845
0.0383 1 0.5
0.5668 1 0.5
0.0633 0.5066 0.4922
0.0659 0.7833 1
0.1149 1 1
0.0676 0.7613 1
0.2582 0.5 0.5
0.0716 0.5597 0.5595
0.0332 0.3335 0.3298
0.0638 1 1
0.0646 0.4686 0.4686
0.0732 0.3447 1
0.032019 0.5 0.5
0.1034 0.8295 1
0.6515 0.5949 0.9007
0.0318 0.6059 0.4888
0.3061 1 0.5
0.0898 0.9131 1
0.1625 1 1
0.0967 0.5 0.5
0.0624 0.3424 0.3335
0.0715 0.8501 1
0.0697 0.546 0.5456
0.1263 0.6296 1
0.1366 1 1
0.094312 0.414048 0.414048
0.0626 0.2516 1
0.1614 0.6269 1
0.263 0.809 0.8317
0.0307 0.2568 0.2502
0.4584 0.4255 0.5845
0.8226 1 1
0.0766 0.3101 1
0.126 1 0.5
0.0368 0.4788 1
0.3327 1 1
0.0622 1 0.5
0.0999 0.5437 1
0.0383 0.2955 1
0.2156 1 1
0.4584 0.4255 0.5845
0.4842 0.2981 0.5058
0.2966 1 0.5
0.0306 0.3164 0.4972
0.0821 0.5 0.5
0.2369 1 0.5
0.3257 0.5567 1
0.1259 0.3468 1
0.2016 1 1
0.2288 1 0.5
0.5998 0.3308 1
0.1921 0.6398 0.5
0.2106 1 0.5
0.1259 0.3468 1
0.0383 0.4655 1
0.1605 1 0.5
0.1899 1 0.5
0.0369 0.3447 1
0.3557 0.4807 0.5
0.0383 1 1
0.0736 1 1
0.5713 1 0.5
0.0691 0.6027 1
0.0708 0.3728 0.3728
0.1625 1 1
0.0947 0.3579 0.8001
0.3995 1 1
0.1259 0.3468 1
0.0338 0.4758 1
0.3484 0.2563 1
0.0331 1 0.5
0.1393 0.4625 0.4362
0.3995 1 1
0.1276 0.3772 1
0.0675 1 1
0.3916 0.9736 1
0.0338 0.4629 1
0.6214 1 1
0.0365 1 0.5
0.0368 0.278 1
0.1919 1 1
0.0383 0.2936 0.2936
0.1259 0.3468 1
0.1475 1 1
0.549 1 0.5
0.4584 0.4255 0.5845
0.6119 0.3491 1
0.0383 1 0.5
0.0664 0.7613 1
0.6515 0.5949 0.9007
0.1294 0.3834 1
0.032 0.6163 1
0.0383 0.9588 1
0.0354 0.4517 1
0.0383 0.355 0.5
0.0369 0.2876 1
0.3864 0.6673 1
0.0656 0.9252 1
0.0343 0.2793 0.272
0.0309 0.3553 1
0.4842 0.2981 0.5058
0.0383 1 0.5
0.1036 1 0.5
0.4842 0.2981 0.5058
0.3327 1 1
0.2304 0.4952 1
0.1613 0.5 0.5
0.3811 0.4714 1
0.032019 0.5 0.5
0.6515 0.5949 0.9007
0.636 1 0.5
0.0383 0.4186 1
0.0982 0.5 0.5
0.1294 0.3834 1
0.0383 1 1
0.0323 0.7539 1
0.1625 1 1
0.2309 1 1
0.0383 0.5 0.5
0.063 0.7586 1
0.0366 0.2701 0.2692
0.0383 1 1
0.0684 1 0.5
0.0946 0.5777 0.6353
0.6515 0.5949 0.9007
0.0624 1 0.5
0.031 0.9036 0.5
0.1023 1 1
0.136 1 0.5
0.0766 0.7755 1
0.3362 1 0.5
0.3078 1 1
0.4584 0.4255 0.5845
0.0657 1 1
0.2433 1 0.5
0.0383 1 1
0.6062 1 1
0.0633 1 1
0.0314 0.466 0.466
0.6026 1 1
0.1308 0.2682 0.2662
0.6515 0.5949 0.9007
0.0693 0.7961 1
0.0308 0.4175 1
0.2397 1 0.5
0.0716 0.2741 0.559
0.0383 1 0.5
0.4603 1 0.5
0.3608 1 0.5
0.0337 0.269 0.2002
0.5759 1 0.5
0.5834 1 0.5
0.1596 0.3336 0.3327
0.0662 0.3084 0.3084
0.0383 1 0.5
0.0623 0.3173 0.3156
0.0708 0.3228 0.5484
0.0727 1 1
0.0383 0.4219 1
0.1636 0.2678 0.2675
0.0323 0.7539 1
0.0737 0.5126 1
0.7725 0.835 1
0.0973 1 0.5
0.0317 0.913 1
0.1919 1 1
0.5983 1 1
0.6412 1 0.5
0.0349 0.5637 1
0.032 0.6163 1
0.0961 0.2654 0.2374
0.033 0.3735 0.3734
0.1132 0.601 1
0.2245 1 1
0.6515 0.5949 0.9007
0.0383 0.7449 0.5
0.1928 0.7561 1
0.6515 0.5949 0.9007
0.1343 1 0.5
0.1429 0.3393 1
0.263 0.8089 0.8317
0.0942 0.371 0.7975
0.6138 1 0.5
0.0625 1 0.5
0.0383 1 0.5
0.263 0.8089 0.8317
0.0649 0.7943 1
0.0383 0.4247 1
0.4103 1 0.5
0.1018 1 1
0.0643 0.3377 0.871
0.1259 0.3468 1
0.7647 0.3597 1
0.1025 1 1
0.6515 0.5949 0.9007
0.5712 0.5 0.5
0.031 0.9036 0.5
0.0383 0.2743 0.6382
0.263 0.5923 0.8317
0.0989 0.6567 0.6411
0.0697 0.367 0.3668
0.2111 0.3998 1
0.0383 0.32 0.549
0.1064 1 1
0.1632 0.2961 0.2959
0.2607 1 1
0.6062 1 1
0.4842 0.2981 0.5058
0.0661 1 1
0.8226 1 1
0.0383 1 0.5
1.0597 0.6539 1
0.0614 0.6814 1
0.5882 1 0.5
0.0687 1 1
0.0681 0.3899 0.9591
1.0597 0.6539 1
0.0641 0.6547 1
0.0666 1 1
0.0383 1 0.5
0.0308 0.3172 1
0.1245 0.5876 0.5876
0.1272 1 1
0.0495 1 0.5
0.3609 0.7368 1
0.05 0.2693 1
0.263 0.5923 0.8317
0.2451 1 0.5
0.4234 1 0.5
0.0383 0.9198 0.5
0.1293 1 1
0.4584 0.4255 0.5845
0.1637 0.3114 0.4634
0.0345 0.4946 0.4858
0.0315 0.5846 0.5
0.0348 0.7053 1
0.1532 1 1
0.1245 0.5876 0.5876
0.0255 0.6557 1
0.1303 0.4142 0.414
0.1591 0.4043 0.4028
0.3551 0.6747 0.5
0.1619 0.3809 1
0.0672 0.3219 0.3219
0.0383 1 0.5
0.656 1 0.5
0.0358 0.6484 1
0.0306 0.7462 1
0.0719 0.9127 1
0.0994 0.5794 0.5
0.0697 1 1
0.7725 0.835 1
0.0756 0.6312 0.5
0.2955 1 1
0.1369 1 0.5
0.3329 0.2526 1
0.037 0.6484 1
0.0656 0.9252 1
0.0188 0.4313 1
0.8226 1 1
0.0383 0.4767 1
0.6138 1 0.5
0.0315 0.3045 0.5
0.1332 1 1
0.0679 0.3358 1
0.0766 0.7755 1
0.0842 0.2862 1
0.0383 0.5662 1
0.0634 0.4222 0.4186
0.2859 1 0.5
0.1306 0.5421 0.5421
0.0696 0.7618 1
0.0921 1 1
0.263 0.809 0.8317
0.0383 0.7304 1
0.0766 0.3101 1
0.0766 0.835 1
0.0383 1 0.5
0.8277 1 0.5
0.8226 1 1
0.0669728 1 1
0.0999 1 0.5
0.2772 0.6087 1
0.0643 0.3377 0.871
0.0645 1 1
0.263 0.5923 0.8317
0.1269 0.3265 0.3263
0.0368 0.278 1
0.2248 0.8155 1
0.3609 0.7368 1
0.0633 1 1
0.4584 0.4255 0.5845
0.0948 0.6532 0.6524
0.5621 0.6051 1
0.2309 1 1
0.0676 0.3879 1
0.0652 1 1
0.047 0.7761 1
0.0338 0.4629 1
0.2304 0.4952 1
0.0346 0.4438 1
0.0383 0.4145 0.6049
0.0383 1 1
0.0945 0.3163 0.3162
0.0308 0.3587 1
0.1044 0.2993 0
0.0383 1 1
0.263 0.5923 0.8317
0.4575 1 0.5
0.0351 0.3421 1
0.0974 0.2907 0.2968
0.5644 0.8356 1
0.263 0.5923 0.8317
0.0646 0.3048 0.3045
0.0307 0.3477 0.4943
0.0321 0.753 1
0.0627 0.6309 1
0.0315 0.5138 0.4999
0.2224 1 1
0.3811 0.4714 1
0.0383 1 0.5
0.0348 0.6996 1
0.5172 1 0.5
0.4584 0.4255 0.5845
0.0618 0.6246 1
0.0973 1 0.5
0.6119 0.3491 1
0.8226 1 1
0.4842 0.2981 0.5058
0.4602 1 0.5
0.0383 0.2587 0.5
0.0312 0.379 1
0.2304 0.4952 1
0.6515 0.5949 0.9007
0.0255 0.2567 1
0.2539 0.6656 0.5
0.0243 0.4993 1
0.4842 0.2981 0.5058
0.0355 0.2725 1
0.1312 0.3065 0.5
0.0506 0.7293 1
0.0641 0.6481 1
0.5668 1 0.5
0.1304 0.3346 0.3342
0.1312 0.3821 0.3819
0.0937 1 1
0.0534 0.6511 1
0.6515 0.5949 0.9007
0.0654 0.7347 1
0.0368 0.4788 1
0.1679 1 0.5
0.1032 1 0.5
0.0383 0.5 0.5
0.3995 1 1
0.5644 0.8356 1
0.0965 1 0.5
0.0936508 0.277999 0.234045
0.8226 1 1
0.0999 0.5437 1
0.7886 1 0.5
0.1612 0.2801 0.2796
0.0383 0.4956 1
0.4858 1 1
0.0308 0.4175 1
0.147 0.3583 1
0.4842 0.2981 0.5058
0.069 1 0.5
0.031 0.8874 1
0.1273 0.2659 0.2564
0.0671 0.7953 1
0.0676 0.3879 1
0.0383 0.4605 1
0.4842 0.2981 0.5058
0.0737 0.5126 1
0.0696 0.7618 1
0.4584 0.4255 0.5845
0.0313 0.306 1
0.0935 0.2715 1
0.4584 0.4255 0.5845
0.4842 0.2981 0.5058
0.5231 1 1
0.0708 0.367 0.367
0.038 0.9444 1
0.3527 0.9737 1
0.1277 0.7367 1
0.0619 0.7054 1
0.1072 1 0.5
0.1263 0.3232 0.7069
0.0663 0.3221 0.3219
0.1273 0.2659 0.2564
0.5644 0.8356 1
0.5639 1 1
0.0383 1 0.5
0.3326 1 0.5
0.0691 0.6027 1
0.0993 0.5 0.5
0.0636 0.3197 1
0.1625 1 1
0.6515 0.5949 0.9007
0.0663 0.7509 1
0.5983 1 1
0.0368 0.278 1
0.1407 1 1
0.4842 0.2981 0.5058
0.0383 0.4545 0.5
0.3811 0.4714 1
0.2309 1 1
0.3257 0.5567 1
0.3215 1 0.5
0.0328 0.7053 1
0.3811 0.4714 1
0.6122 1 1
0.095 0.2934 0.2929
0.6515 0.5949 0.9007
0.2874 0.6553 1
0.5452 0.4811 0.5
0.1978 0.3218 1
0.0332 0.3562 1
0.0383 1 1
0.0308 0.9274 1
0.2837 1 0.5
0.1309 0.3644 0.3624
0.0696 0.7618 1
0.3739 0.4903 1
0.054 1 1
0.0999 1 0.5
0.0383 1 1
0.0693 0.7958 1
0.0766 0.7124 1
0.1294 0.3834 1
0.01 0.3216 0.5
0.3629 1 1
0.3901 0.7328 1
0.0368 1 0.5
0.031 0.9523 0.952
0.2304 0.4952 1
0.0383 0.4865 1
0.0708446 0.366129 0.34807
0.5062 1 0.5
0.0691 0.6027 1
0.1256 1 1
0.2248 0.8155 1
0.0719 0.9127 1
0.4584 0.4255 0.5845
0.6515 0.5949 0.9007
0.5998 0.3308 1
0.0739 0.5517 0.5517
0.2261 0.6961 1
0.1325 0.8144 1
0.1223 0.3002 1
0.1292 0.4144 0.4142
0.1282 0.3892 0.3884
0.1006 0.4376 1
0.3118 0.5 0.5
0.5452 1 0.5
0.037 0.5382 1
0.3215 0.5754 1
0.1914 0.6788 1
0.0652 0.7718 1
0.5639 1 1
0.164 1 0.5
0.7725 0.835 1
0.4584 0.4255 0.5845
0.0348 0.6996 1
0.0973 1 1
0.0383 1 0.5
0.0383 0.4958 1
0.0671 0.7951 1
0.263 0.5923 0.8317
0.0676 0.3879 1
0.0679 1 0.5
0.5675 1 0.5
0.1259 0.3468 1
0.0685 0.5471 0.5467
0.0614 0.6127 1
0.0664 0.7037 1
0.0354 0.4517 1
0.0368 0.278 1
0.0784 0.7049 1
0.29554 1 0.5
0.0725 1 1
0.0366 0.2935 1
0.4842 0.2981 0.5058
0.4842 0.2981 0.5058
0.1991 1 0.5
0.0331 1 1
0.5337 1 0.5
0.0306 1 0.5
0.0383 0.9588 1
0.0306 0.3628 0.5
0.8226 1 1
0.1429 0.3393 1
0.3304 1 1
0.0953 1 1
0.0306 0.45 1
0.0357 0.4455 1
0.0635 0.3048 0.2697
0.5858 1 1
0.0355 0.2725 1
0.0939 1 1
0.3739 0.4903 1
0.0332 0.3562 1
0.0339 1 0.5
0.3811 0.4714 1
0.3952 1 0.5
0.16 0.315 0.315
0.2304 0.4952 1
0.3629 1 1
0.2108 1 1
0.1917 0.4141 1
0.0633 0.8912 1
0.0989 0.6567 0.6411
0.3811 0.4714 1
0.2548 1 1
0.1634 0.2552 0.255
0.1576 0.3201 0.3188
0.0618 0.5034 0.5034
0.4842 0.2981 0.5058
0.031 0.7616 0.9134
0.0255 0.2567 1
0.0323 0.5 0.5
0.0383 1 1
0.0732 0.3447 1
0.3327 1 1
0.0383 0.6484 1
0.2309 1 1
0.3609 0.7368 1
0.032019 0.5 0.5
0.0343 0.4773 0.4755
0.3982 1 1
0.5078 1 0.5
0.2304 0.4952 1
0.4842 0.2981 0.5058
0.0654 0.3125 0.3125
0.4842 0.2981 0.5058
0.066 0.4897 0.5
0.0368 0.278 1
0.0383 1 0.5
0.0383 0.9692 1
0.3541 0.7682 0.5
0.0317 0.3763 1
0.0383 0.4335 0.5
0.0311 0.4201 1
0.0383 0.4032 1
0.0378 1 0.5
0.5786 1 0.5
0.0681 0.3899 0.9591
0.1612 0.3139 0.3129
0.0308 0.7688 0.5
0.2955 1 1
0.263 0.5923 0.8317
0.0708 0.3228 0.5484
0.3609 0.7368 1
0.0383 0.9588 1
0.0726 0.5691 0.5691
0.0688 1 1
0.0689 0.3211 0.3211
0.0383 0.385 1
0.0323 0.5105 0.9992
0.3609 0.7368 1
0.031 0.9036 0.5
0.037 0.4482 0.5
0.6219 1 0.5
0.4842 0.2981 0.5058
0.0698 0.3665 0.3663
0.093 0.4226 0.4484
0.4251 1 0.5
0.3557 0.6869 1
0.0698 0.5315 0.5311
0.0953 1 1
0.0659 0.2548 1
0.0383 0.9588 1
0.0383 0.2804 0.5
0.0383 1 0.5
0.5742 1 1
0.0705 0.552 0.552
0.0383 0.359 1
0.3327 1 1
0.0696 0.7618 1
0.0966 0.2677 0.2676
0.0622 0.7377 1
0.5636 0.5 0.5
0.3339 0.5 0.5
0.0654 0.7347 1
0.1131 0.2805 1
0.0338 0.4629 1
0.4842 0.2981 0.5058
0.0383 1 1
0.5644 0.8356 1
0.0728 0.5516 0.5516
0.8226 1 1
0.0383 0.9588 1
0.0682 1 0.5
0.0676 1 1
0.0942 1 0.5
0.031 0.5876 1
0.0627 0.6309 1
0.0629 0.9398 1
0.162 0.297 0.297
0.0366 0.3586 0.5
0.0636 0.3197 1
0.0383 0.3701 0.5
0.0496 1 0.5
0.3629 1 1
0.0719 0.9127 1
0.2548 1 1
0.0696 0.7618 1
0.0691 0.6027 1
0.034 0.4493 1
0.0312 0.2517 1
0.0627 1 0.5
0.0657 0.7945 1
0.0708 0.3228 0.5484
0.2487 1 0.5
0.0312 0.41 1
0.5786 1 0.5
0.0496 0.4617 1
0.0313 1 1
0.3428 0.8401 0.5
0.0654 0.5174 0.5174
0.1042 1 1
0.0632 1 0.5
0.4842 0.2981 0.5058
0.0306 0.3778 1
0.0628 0.6075 0.6974
0.024 1 1
0.0383 1 0.5
0.0255 0.6557 1
0.5078 1 0.5
0.0314 0.3088 1
0.0951 0.3024 0.3497
0.2304 0.4952 1
0.8226 1 1
0.4584 0.4255 0.5845
0.7647 0.3597 1
0.0383 1 0.5
0.4842 0.2981 0.5058
0.032 0.9532 1
0.0383 1 1
0.1294 0.3834 1
0.1149 1 1
0.1017 1 1
0.1853 0.4505 1
0.031 0.9523 0.952
0.0383 1 1
0.3025 1 1
0.0383 0.9488 0.5
0.0383 0.5 0.5
0.263 0.5923 0.8317
0.0383 1 1
0.1343 1 0.5
0.0973 1 0.5
0.037 0.643 1
0.0626 0.3026 0.3019
0.1347 1 0.5
0.1665 1 1
0.0368 0.7433 0.6532
0.0383 1 1
0.3327 1 1
0.1428 1 1
0.8226 1 1
0.0348 0.3486 0
0.0653 1 0.5
0.033 0.7053 1
0.0655 0.6958 1
0.0354 0.4517 1
0.6977 1 1
0.1312 0.5244 1
0.1413 0.4622 0.4601
0.1364 1 0.5
0.0667 1 1
0.0255 0.2567 1
0.0656 0.9252 1
0.1034 1 1
0.0979 1 1
0.0335 0.6536 0.6467
0.0619 0.7054 1
0.0624 0.2956 1
0.0969 0.2685 0.2672
0.0316 1 1
0.0331 1 1
0.0312 1 1
0.4842 0.2981 0.5058
0.0383 0.4344 1
0.6119 0.3491 1
0.0338 0.4629 1
0.2324 1 1
0.2548 1 1
0.6119 0.3491 1
0.3557 0.6869 1
0.1638 0.2678 0.2674
0.3557 0.6869 1
0.146 1 0.5
0.0534 0.6511 1
0.4584 0.4255 0.5845
0.1079 1 1
0.0973 1 1
0.1294 0.3834 1
0.0306 0.3164 0.4972
0.6021 0.5 0.5
0.0628 0.6075 0.6974
0.0673 0.7671 1
0.099 0.4733 1
0.0665 0.7613 1
0.0736 1 1
0.0719 0.9127 1
0.187 1 1
0.0376 0.4455 1
0.0935 0.2715 1
0.0534 0.4564 1
0.0646 0.4686 0.4686
0.4842 0.2981 0.5058
0.1626 0.2676 0.2675
0.0311 0.4455 1
0.0999 0.6659 0.6485
0.9741 1 1
0.1919 1 1
0.4842 0.2981 0.5058
0.3315 1 0.5
0.0383 0.8674 1
0.0383 0.5614 0.5
0.0368 0.278 1
0.8226 1 1
0.0716 0.5522 0.5522
0.718 0.3489 0.7085
0.2304 0.4952 1
0.4666 1 1
0.1308 0.2682 0.2662
0.0383 0.4705 1
0.0619 0.7308 1
0.0368 0.278 1
0.1036 1 0.5
0.2304 0.4952 1
0.0633 1 1
0.0981 0.2552 0.2537
0.1131 0.2805 1
0.0383 0.2564 0.5
0.0739 0.5517 0.5517
0.1263 0.3232 0.7069
0.1259 0.3468 1
0.0942 0.371 0.7975
0.0307 0.3822 1
0.6214 1 1
0.8226 1 1
0.5983 1 1
0.6515 0.5949 0.9007
0.6062 1 1
0.0383 0.5281 1
0.0633 1 1
0.073 0.5 0.5
0.3982 1 1
0.0645 0.256 1
0.1003 0.4744 0.4426
0.032 0.6163 1
0.29 0.5 0.5
0.6062 1 1
0.0645 0.3634 0.3627
0.0677 1 1
0.066 0.4897 0.5
0.0365 0.7308 1
0.027 1 1
0.6515 0.5949 0.9007
0.8226 1 1
0.0614 0.6006 1
0.031 1 1
0.3811 0.4714 1
0.8226 1 1
0.3257 0.5567 1
0.0935 0.2715 1
0.0978 1 0.5
0.0307 1 0.5
0.4218 1 0.5
0.0383 0.4713 1
0.16 0.3825 0.3785
0.1278 1 0.5
0.4842 0.2981 0.5058
0.0655 0.7612 1
0.032 0.6163 1
0.345 1 1
0.3327 1 1
0.0637 1 1
0.2955 1 1
0.5231 1 1
0.1259 0.3468 1
0.0309 0.3023 1
0.101 1 0.5
0.7924 1 1
0.0315 0.3938 0.5147
0.0679 0.927 1
0.4584 0.4255 0.5845
0.4261 1 0.5
0.0383 0.3232 0.3132
0.0503 0.3914 1
0.0314 0.4438 1
0.3811 0.4714 1
0.0383 0.7791 1
0.1612 0.2801 0.2796
0.1383 0.4617 0.4247
0.0383 0.5598 0.5
0.2812 1 1
0.0732 0.3447 1
0.062 0.2997 0.2994
0.263 0.5923 0.8317
0.4616 1 0.5
0.0639 1 1
0.0708 0.5532 0.553
0.5097 1 1
0.0351 0.4248 1
0.1684 0.3792 1
0.1006 0.4376 1
0.0939 0.6095 1
0.1601 0.3138 0.3135
0.7289 1 1
0.1261 1 1
0.0369 0.2876 1
0.0654 0.7347 1
0.0383 0.4868 1
0.0956 0.4487 0.4487
0.0652 0.7608 1
0.0351 0.3421 1
0.2634 0.8 1
0.2196 0.5 0.5
0.0655 0.5243 1
0.0996 0.7486 0.7475
0.6122 1 1
0.16 0.6259 1
0.0691 0.6027 1
0.0698 0.3665 0.3665
0.6515 0.5949 0.9007
0.3609 0.7368 1
0.0383 1 0.5
0.1555 1 1
0.0373 1 1
0.1245 0.5876 0.5876
0.0672 0.8949 1
0.0369 0.2876 1
0.8226 1 1
0.641 1 0.5
0.2309 1 1
0.0766 1 0.5
0.0766 0.3101 1
0.0955 1 1
0.0383 1 0.5
0.5644 0.8356 1
0.1023 0.4899 1
0.1667 0.2604 0.2603
0.2501 0.6346 0.5
0.0317 0.4337 1
0.3739 0.4903 1
0.8226 1 1
0.1264 0.2835 0.2824
0.1899 1 0.5
0.0306 1 1
0.1064 1 1
0.0677 1 1
0.3329 0.2526 1
0.0306 0.547 0.5438
0.4584 0.4255 0.5845
0.263 0.5923 0.8317
0.0369 0.5351 1
0.0308 0.382 1
0.0308 0.5725 1
0.0708 0.3228 0.5484
0.2124 1 0.5
0.1036 1 0.5
0.1667 0.2604 0.2603
0.0383 1 1
0.0383 1 1
0.7725 0.835 1
0.0659 0.7833 1
0.5806 1 0.5
0.2156 1 1
0.0659 0.4539 1
0.3697 1 0.5
0.0383 0.4674 1
0.0636 0.3197 1
0.2304 0.4952 1
0.3336 1 0.5
0.5621 0.6051 1
0.1919 1 1
0.263 0.809 0.8317
0.0718 0.6409 0.7224
0.3901 1 1
0.0627 1 1
0.0675 1 0.5
0.0645 0.46 1
0.0626 0.7066 0.7061
0.4584 0.4255 0.5845
0.1312 0.3065 0.5
0.0383 0.435 0.5
0.5644 0.8356 1
0.0327 0.3952 1
0.1589 0.5 0.5
0.5097 1 1
0.0623 0.3173 0.3156
0.0687 1 1
0.0383 1 0.5
0.0634 0.4222 0.4186
0.6122 1 1
0.0318 0.3952 1
0.8226 1 1
0.0357 0.3605 0.5
0.0435171 0.550552 0.542519
0.1941 0.3855 1
0.0383 0.5281 1
0.0656 0.9252 1
0.0705 0.3941 1
0.0614 0.6634 0
0.0383 0.7749 1
0.0284 1 1
0.1017 0.4006 1
0.3982 1 1
0.1637 0.3114 0.4634
0.1259 0.3468 1
0.0684 1 0.5
0.0383 0.4798 1
0.0718 1 1
0.5644 0.8356 1
0.031 0.7616 0.9134
0.3615 1 1
0.4023 1 1
0.0707 0.5537 0.5537
0.0617 1 1
0.8226 1 1
0.0669 0.4892 0.5
0.16 0.3116 0.3115
0.3982 1 1
0.6515 0.5949 0.9007
0.1072 1 0.5
0.3078 1 1
0.0293 1 1
0.031 0.9036 0.5
0.0698 0.2611 0.3234
0.4584 0.4255 0.5845
0.0727 0.5606 0.5606
0.0358 0.6484 1
0.3327 1 1
0.0708 0.3228 0.5484
0.6515 0.5949 0.9007
0.0627 0.7156 0.6975
0.0383 0.4412 1
0.263 0.5923 0.8317
0.0352 0.6669 1
0.391 1 0.5
0.1259 0.3468 1
0.0646 0.3032 0.3032
0.1371 1 0.5
0.1658 0.3034 0.3033
0.3025 1 1
0.5906 1 1
0.0681 1 0.5
0.7292 0.3907 1
0.0631 0.8928 1
0.3061 1 0.5
0.7725 0.835 1
0.0338 0.7632 1
0.0667 0.9259 1
0.4107 0.5 0.5
0.0383 0.6548 1
0.0332 0.3477 0.6674
0.0627 0.5035 0.5035
0.4584 0.4255 0.5845
0.5663 1 0.5
0.0383 0.5 0.5
0.0667 1 1
0.0383 0.9588 1
0.0665 1 1
0.0696 0.7618 1
0.3703 1 0.5
0.0639 1 1
0.2087 1 1
0.6515 0.5949 0.9007
0.0383 0.6834 0.5
0.1335 1 0.5
0.0383 1 0.5
0.062 1 1
0.0368 0.278 1
0.146 1 0.5
0.1625 1 1
0.2356 0.6942 1
0.0352 0.8726 1
0.4842 0.2981 0.5058
0.4842 0.2981 0.5058
0.1277 1 0.5
0.2304 0.4952 1
0.1366 1 1
0.0696 0.5507 0.5503
0.0693 0.7958 1
0.1024 1 1
0.1644 0.7726 1
0.1631 0.3428 0.3414
0.0627 0.9025 1
0.0316 0.4865 0.48
0.3745 1 0.5
0.0345 0.6433 1
0.0383 1 1
0.2304 0.4952 1
0.0357 0.4455 1
0.0317 0.465 1
0.0626 1 1
0.0696 0.5507 0.5503
0.0383 1 0.5
0.0348 0.6996 1
0.0366 1 1
0.0655 0.3056 0.3055
0.2304 0.4952 1
0.0325 0.4747 1
0.0369 0.2876 1
0.4842 0.2981 0.5058
0.0623 0.3129 0.3127
0.1259 0.3468 1
0.0383 0.6255 0.6026
0.0321 0.391 0.9709
0.0383 0.9588 1
0.0708 0.3666 0.3666
0.1791 0.5472 1
0.0766 0.4653 1
0.263 0.809 0.8317
0.0698 0.2611 0.3234
0.1337 1 1
0.2304 0.4952 1
0.0614 0.6814 1
0.1379 1 1

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

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Gene identifier MUP045 (Mycobacterium ulcerans), beta-ketoacyl synthase-like protein
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